PRODUCTS

ZPT ZINC PYRITHIONE

ZPT Zinc Pyrithione also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
ZPT Zinc Pyrithione’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.
ZPT Zinc Pyrithione react with cationic and non-ionic surfactants forming insoluble precipitate, unstable in the light and oxidizer, when at higher temperatures ,ZPT Zinc Pyrithione is not stable to acids and bases.

CAS Number: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 317.7
EINECS Number: 236-671-3

Synonyms:Zinc pyrithione, 13463-41-7, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, biokera, shampoo, bis(N-oxopyridine-2-thionato)zinc (II), Balancing, Chevance, Dandrene, Elementz, Medaclear, Treatment, Vanicream, Zincopan, Zolidyne, classic control, LuckyClassic, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Bioxsine Series, Dandruff Detox, Everyday Clean, Pyrithion-Zink, Pyrithionr Zinc, Pyrithions Zinc, Pyritione Zinc, Royal Dandruff, Zinc-pyrion, American Crew, CCRIS 4894, Classic Clean, Zinc Therapy, HairQ, Zinc soap, Zn-pyrion, Clean Apple, CyzoneBe Sexy, Four Season, Happy Cappy, Head Remedy, Itchy Scalp, LuckyDry Hair, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Shiny and Sleek, Dry Scalp, Free and Clear, Blue Cap, Crawford Dandruff, HSDB 4498, Vanicream Z-Bar, Zinc 1-hydroxy-2-pyridinethione, Blue Cap Cream, Dry Scalp Care, Smooth and glossy, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, LIFECELL Womens, Dry Scalp Dandruff, Lucky2in1 Classic, FSB 8332, Pyrithionum zincicum, EpochAva Puhi Moni, 2 in 1 Dandruff, 2-Pyridinethiol-1-oxide, zinc salt, Antidandruff Shampoo, Dandruff 2 in 1, EINECS 236-671-3, EquateEveryday Clean, Fresh Mint Dandruff, LIFECELL Mens, Vegetability Natural, 2-Mercaptopyridine 1-oxide zinc salt, 2-mercaptopyridine-1-oxide zinc salt, HEAD AND SHOULDERS CONDITIONER, Aloe Coal 01, ANTIDANDRUFF, Divine Dandrene 1%, Divine Dandrene 2%, FRUITOPIA, HEBDANDRUFF, Pyrithione Zinc 1%, REVOX, SAFEWAYDANDRUFF, AxeFeeze AntiDandruff, GKhair Anti-Dandruff, MOJELIM Dr, Sulfur 8 Aqua Blue, WeCare Anti-Dandruff, Anti-Dandruff Shampoo, Bis(2-pyridylthio)zinc 1,1'-dioxide, Control Anti-Dandruff, EPA Pesticide Chemical Code 088002, LEudine Anti-dandruff, Nioxin Scalp Recovery, NSC 290409, Simply Clean Dandruff, AxeFreeze AntiDandruff, DAMOAE THERAPY, PYRITHIONE ZINE, SHIKATRI CLASS, Vancide ZP Dispersion, 2 in 1 Antidandruff, BALLVIC SEBO, REBIRTH HAIR, Pert Plus 2 in 1, pyrithione zinc shampoo, SELEX DNA, X FOLATE, AxeAntiDandruff Styling, Everyday Clean Dandruff, Satinique Anti Dandruff, dandruff therapy shampoo, Equaline DandruffRefresh, HAIRJOY MSM HAIR, Personal CAREDry Scalp, Shampoo plus Conditioner, Control Dandruff Therapy, Pert Plus Dandruff Plus, AffirmCare Scalp Therapy, AI3-62421, HEAD AND SHOULDER, MEDECEAN SEBORRHEA, DR. SCALP ACTIVE, modesa 2 in 1 dandruff, Shelo NABEL Anti Caspa, Apex Crown Anti Dandruff, Daylogic Refresh Dandruff, Dermaharmony Zinc Therapy, Royal Dandruff Dry Scalp, Sereve Professional Scalp, Zincon Medicated Dandruff, Head and Shoulders 2in1, MSM HAIR SIGNATURE, Personal CAREDaily Clean, ZENOTRI Scalp Shampoo., Balmers Cooling Zone 31, Pyrithione Zinc 0.22%, Dermaharmony Tea Tree Bar, Dermaharmony Unscented Bar, Equate Dry Scalp Dandruff, Aloe Coal 02 Conditioner, BYE-BYE CRADLE CAP, CVS PHARMACYDANDRUFF, DG BODYSIMPLY CLEAN, Natural 17 Anti-Dandruff, P.O.V. Classic Dandruff, SAFEWAY CAREDANDRUFF, URBAN WASH DANDRUFF, Dermaharmony Face and Body, Dry Scalp CareDandruff MD, Head and Shoulders Coconut, Daylogic 2 in 1 Dandruff, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, EQUALINECLASSIC CLEAN, ESIKAMen Effective Control, Head and Shoulders Grooming, Head and Shoulders Scalp X, MOISTURIZING DANDRUFF, OREAD BLUE Anti-Dandruff, SuaveMen 2 in 1 Dandruff, ZENOTRI Follicle Shampoo., Classic Control Antidandruff, Daylogic Dry Scalp Dandruff, Dermaharmony Pyrithione Zinc, LBELHOMME ANTIDANDRUFF, UNII-R953O2RHZ5, 2in1Dandruff and Conditioner, Australian Gold Defense Zone, Hair and Scalp anti-dandruff, Marcs Everyday Care Dandruff, Sebastian Purist Antidandruff, Selsun Blue Itchy Dry Scalp, P.O.V. Dry Scalp Dandruff, Sulfur 8 Kids Anti-Dandruff, 2 in 1, Head and Shoulders Dual Pack, Head and ShouldersGreen Apple, Head and ShouldersItchy Scalp, BLADE HOWLANTI-DANDRUFF, Equaline DandruffClassic Clean, Equate Everyday Clean Dandruff, Halsa Pyrithione Zinc Dandruff, Head and ShouldersVolume Boost, Hyvee Care Dry Scalp Dandruff, Leader Dandruff Everyday Clean, Marcs Dry Scalp Care Dandruff, Mizani Scalp Care Antidandruff, Modesa Dandruff Everyday Clean, Royal Dandruff Dry Scalp Care, AxeArmor AntiDandruff 2 in 1, Head and Shouldersmenthol fresh, SIMPLY BODYCARE DANDRUFF, ClearComplete Care AntiDandruff, Daylogic Dandruff Classic Clean, First Aid Beauty Anti-Dandruff, Head and Shoulders Coconut Kit, Head and Shoulders Shea Butter, Head and Shoulders Styling Gel, Head and ShouldersClassic Clea, 1-HYDROXY-2-PYRIDINE THIONE, ZN SALT;1-HYDROXYPYRIDINE-2-THIONE ZINC;Pyrithione zincique;Bis[(1-oxylatopyridinium)-2-ylthio] zinc;Bis[(1-oxylatopyridinium-2-yl)thio]zinc;Bis[[(pyridine 1-oxide)-2-yl]thio] zinc salt;Bis(2-pyridylthio) Zinc 1,1'-Dioxide 1-Hydroxypyridine-2-thione Zinc Salt 2-Pyridinethiol 1-Oxide Zinc Salt Zinc Pyrithione;zincpolyanemine

ZPT Zinc Pyrithione is not compatible with EDTA, non-ionic surfactants make it partially deactivated.
When with the presence of heavy metals, chelation or anti-sequestration will occur, and these chelates are insoluble in water.
EEC and GB7916-87 provide that maximum allowable concentration of mass fraction of ZPT Zinc Pyrithione on cosmetics is 0.5%, only for cleaning after using products.

General concentration 250~1000mg/kg (active), ZPT Zinc Pyrithione can be used in gels, creams, lotions, talcum powder and antidandru shampoo, deodorant and also for disinfecting articles.
In solution, however, the dimers dissociate via scission of one Zn-O bond.
ZPT Zinc Pyrithione was first described in the 1930s.

ZPT Zinc Pyrithione is white to yellow crystalline powder.
ZPT Zinc Pyrithione react with cationic and non-ionic surfactants forming insoluble precipitate, unstable in the light and oxidizer, when at higher temperatures, it is not stable to acids and bases.
ZPT Zinc Pyrithione is not compatible with EDTA, non-ionic surfactants make it partially deactivated.

When with the presence of heavy metals, chelation or anti-sequestration will occur, and these chelates are insoluble in water.
EEC and GB7916-87 provide that maximum allowable concentration of mass fraction of ZPT Zinc Pyrithione on cosmetics is 0.5%, only for cleaning after using products.
General concentration 250~1000mg/kg (active), ZPT Zinc Pyrithione can be used in gels, creams, lotions, talcum powder and anti-dandruff shampoo, deodorant and also for disinfecting articles.

ZPT Zinc Pyrithione is a coordination complex of zinc that is widely used for its antifungal and antibacterial properties.
It is a fine, powdery substance that can range in color from white to orange or green, depending on its formulation and purity.
ZPT Zinc Pyrithione is well known for its effectiveness in treating dandruff and seborrheic dermatitis, which is why it is commonly found in medicated shampoos and skincare products.

ZPT Zinc Pyrithione is a coordination complex of zinc.
ZPT Zinc Pyrithione has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
ZPT Zinc Pyrithione is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent.

ZPT Zinc Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.
ZPT Zinc Pyrithione is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Experiments conducted under sterile conditions with a light:dark cycle of 12:12 hours have shown that, under exposure to light, the concentration of ZPT Zinc Pyrithione in pH 9 buffer was reduced to 33% of the radioactivity added in 15 min.

ZPT Zinc Pyrithione is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.
ZPT Zinc Pyrithione works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Additionally, ZPT Zinc Pyrithione aids in controlling sebum production, contributing to a healthier scalp environment.

The chemical formula of ZPT Zinc Pyrithione is C10H8N2O2S2Zn.
ZPT Zinc Pyrithione is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
However,their efficacy has not been substantiated by controlled studies.

There is also some evidence that shampoos with antifungal agents (e.g.ketoconazole)can have a beneficial effect on scalp conditions.
Data from this study also demonstrated that less than 5% of the 14C added occurred as zinc pyrithione after 1 hour of exposure to light.
Similar results have been achieved when photolysis of zinc pyrithione was investigated by use of artificial seawater.

In this study, the parent compound constituted 45% of the radioactivity added after 15 min while, after 24 hours, 1.3% of the added dose occurred as zinc pyrithione.
The estimated half-lives of the photolytic transformation of zinc pyrithione was 13 min in pH 9 buffer and 17.5 min in artificial seawater.
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.

In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.
Primarily utilized in cleansing formulations like shampoos and soap, this ingredient effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

ZPT Zinc Pyrithione and shampoos with selenium sulide have been reported to be effective in the treatment of scalp psoriasis.
ZPT Zinc Pyrithione should be noted, however, that the effectiveness of these shampoos is much smaller than these containing tars, corticosteroids or keratolytics.
ZPT Zinc Pyrithione is very rapidly transformed by photolysis.

Melting point: approximate 240℃
Density: 1.782 g/cm³ (Temp: 25 °C)
Vapor pressure: 0 Pa at 25℃
Storage temp.: Sealed in dry, Room Temperature
Solubility: almost transparency in Pyridine
Form: Powder
Color: White to Orange to Green
Odor: Mild Characteristic
Water Solubility: Insoluble (<0.1 g/100 mL at 21 ºC)
Merck: 14,7994
InChI: InChI=1S/2C5H5NOS.Zn/c27-6-4-2-1-3-5(6)8;/h21-4,8H;/q;;+2/p-2
InChIKey: OTPSWLRZXRHDNX-UHFFFAOYSA-L
SMILES: C1(C=CC=C[N+]=1[O-])S[Zn]SC1C=CC=C[N+]=1[O-]
LogP: 0.9 at 25℃ and pH 7.5-7.7
Surface tension: 73 mN/m at 7.22 mg/L and 20℃

ZPT Zinc Pyrithione is the active ingredient in several shampoos used to control dandru and seborrheic dermatitis and is also eective in the therapy of tinea versicolor.
ZPT Zinc Pyrithione remains unclear whether the benecial eects are caused by an antiproliferative or antimicrobial eect or both.
ZPT Zinc Pyrithione is substantive to the hair, allowing continued therapeutic eect after washing.

ZPT Zinc Pyrithione is a coordination complex of zinc.
ZPT Zinc Pyrithione has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandru.
ZPT Zinc Pyrithione is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.

ZPT Zinc Pyrithione is an active ingredient designed to treat dandru, seborrheic dermatitis, and various fungal infections of the skin and scalp.
ZPT Zinc Pyrithione works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce akiness, itching, and irritation.
Additionally, ZPT Zinc Pyrithione aids in controlling sebum production, contributing to a healthier scalp environment.

The chemical formula of ZPT Zinc Pyrithione is C10H8N2O2S2Zn.
ZPT Zinc Pyrithione is an eective antimicrobial to fungi and bacteria, which can eectively kill the fungi that cause dandru.
ZPT Zinc Pyrithione has long been used as anti-dandru agent and widely used in various popular shampoos.

ZPT Zinc Pyrithione is supplied as a powder or as a 50% water suspension emulsion.
The ne particle size of ZPT Zinc Pyrithione can eectively prevent precipitation and double the antimicrobial eect.
ZPT Zinc Pyrithione is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.

It has long been used as anti-dandruff agent and widely used in various popular shampoos.
ZPT Zinc Pyrithione is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of ZPT Powder can effectively prevent precipitation and double the antimicrobial effect.

ZPT Zinc Pyrithione also serves as a biocide in paints, coatings, and industrial applications to prevent the growth of fungi and bacteria.
It has low water solubility, making it effective for long-lasting protection in various environments.
Despite its benefits, the use of ZPT Zinc Pyrithione has been restricted in some regions due to concerns about its potential environmental impact, particularly its toxicity to aquatic life.

ZPT Zinc Pyrithione is known to exhibit antibacterial activity by disrupting cell membrane integrity and essential metabolic functions in bacteria.
ZPT Zinc Pyrithione is synthesized through a multistep chemical process.
Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.

ZPT Zinc Pyrithione undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
The product is then filtered, washed, and dried to obtain a fine powder.
ZPT Zinc Pyrithione is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.

ZPT Zinc Pyrithione is active against the bacteria E. coli, S. aureus, K. pneumoniae, A. baumannii, P. aeruginosa, E. faecium, E. faecalis, and E. cloacae (MICs = 1-4 μg/ml) and the fungus P. ovale when used at concentrations ranging from 0.01 to 10 μg/ml.
ZPT Zinc Pyrithione reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg/kg per week for six weeks.
Formulations containing zinc pyrithione have been used in the treatment of dandruff.

ZPT Zinc Pyrithione is the active ingredient in several shampoos used to control dandruff and seborrheic dermatitis and is also effective in the therapy of tinea versicolor.
It remains unclear whether the beneficial effects are caused by an antiproliferative or antimicrobial effect or both.
ZPT Zinc Pyrithione is substantive to the hair, allowing continued therapeutic effect after washing.

Organometallics, such as ZPT Zinc Pyrithione, are reactive with many other groups.
Incompatible with acids and bases.
Organometallics are good reducing agents and therefore incompatible with oxidizing agents.

Often reactive with water to generate toxic or flammable gases.
ZPT Zinc Pyrithione antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.
A study from 2011 showed that antifungal effects of Zinc pyrithione work by copper toxicity mechanism that targets critical iron–sulphur proteins.

ZPT Zinc Pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several anti-dandruff shampoos and body wash gels.
In its industrial forms and strengths, it may be harmful by contact or ingestion.
ZPT Zinc Pyrithione can in the laboratory setting trigger a variety of responses, such as DNA damage in skin cells.

Use of zinc pyrithione is prohibited within cosmetic products in the European Union since December 2021.
The substance was considered safe for use in rinse-off and leave-in products of different tested concentrations, but due to potential environmental toxicity consideration of the use of zinc pyrithione was made against potential alternative substance ingredients.
Due to no industry submission to the regulators supporting the continued use of zinc pyrithione and/or an absence of indications that there were no suitable alternatives to the substance: the use of zinc pyrithione became automatically prohibited within cosmetic products as an intended ingredient.

This was as a consequence of ZPT Zinc Pyrithione addition to the Cosmetic Product Regulation (EC) No 1223/2009 Annex II list.
ZPT Zinc Pyrithione concentration of up to 2% is allowed for products when they are formulated to be applied and then washed off after brief exposure.
Alternatively, up to 0.25 percent when formulated to be left on the skin or scalp.

A large Swedish study shows that it is broken down in wastewater plants and does not release into waterways.
A Danish study shows that it biodegrades quickly, but that a risk of continuous leaching from boat paint may cause environmental toxicity.
ZPT Zinc Pyrithione is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent.

At room temperature ZPT Zinc Pyrithione is white to yellow crystalline powder. Slight characteristic odor.
ZPT Zinc Pyrithione shampoos (in concentrations between 1 to 2%) and shampoos with selenium sulide have been reported to be eective in the treatment of scalp psoriasis.
However,their ecacy has not been substantiated by controlled studies.

There is also some evidence that shampoos with antifungal agents (e.g.ketoconazole)can have a benecial eect on scalp conditions.
ZPT Zinc Pyrithione should be noted, however, that the eectiveness of these shampoos is much smaller than these containing tars, corticosteroids or keratolytics.

Uses Of ZPT Zinc Pyrithione:
ZPT Zinc Pyrithione also alleviates symptoms like itching, aking, and redness on the scalp and skin.
ZPT Zinc Pyrithione’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, oering consumers relief from common dermatological issues with proven ecacy.

One of the most common uses of ZPT Zinc Pyrithione is in medicated shampoos to treat dandruff and seborrheic dermatitis.
ZPT Zinc Pyrithione works by reducing the growth of Malassezia, a yeast-like fungus that contributes to dandruff.
Skincare Products: ZPT is sometimes included in creams and lotions to treat fungal skin conditions such as athlete’s foot and eczema.

Its antibacterial properties help control odor-causing bacteria.
ZPT Zinc Pyrithione is used as an antifungal and antibacterial additive in paints, coatings, and sealants to prevent mold and mildew growth on surfaces.
It is incorporated into plastic materials and fabrics to inhibit microbial contamination and prolong product lifespan.

Some prescription creams and ointments use ZPT Zinc Pyrithione to treat fungal infections of the skin.
While not common, certain pharmaceutical formulations may use ZPT for its antimicrobial effects.
Some antibacterial soaps and body washes contain ZPT Zinc Pyrithione to help combat skin infections and bacteria.

ZPT Zinc Pyrithione is occasionally added to detergents to help remove bacteria and fungi from clothing.
ZPT Zinc Pyrithione is used in marine paints to prevent algae, barnacle, and fungal growth on ships and underwater structures.
It is sometimes included in water treatment solutions to prevent microbial contamination.

Shampoo for dandruff,zinc pyrithione can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.
ZPT Zinc Pyrithione is also used as a cosmetic preservative, oil, paint biocide.
ZPT Zinc Pyrithione has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff.

ZPT Zinc Pyrithione is a preservative against bacteria, fungi, and yeast.
It is unstable in light and in the presence of oxidizing agents.
ZPT Zinc Pyrithione is useful in gels, creams, heavy lotions, and talcum powder.

Reactions may lead to photosensitive eczema and actinic reticuloid syndrome.
ZPT Zinc Pyrithione is used as antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.
ZPT Zinc Pyrithione is directly cytotoxic and has antimicrobial effects. Zinc pyrithione is found in many shampoos (DHS-Zinc, Head and Shoulders) and should be applied for 5 minutes daily for 2 weeks.

ZPT Zinc Pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor,[9][8] and vitiligo.

Because of its low solubility in water (8 ppm at neutral pH), ZPT Zinc Pyrithione is suitable for use in outdoor paints and other products that protect against mildew and algae.
ZPT Zinc Pyrithione is an algaecide.
It is chemically incompatible with paints relying on metal carboxylate curing agents.

When it is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
ZPT Zinc Pyrithione is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.
ZPT Zinc Pyrithione is an antibacterial treatment for household sponges, as used by the 3M Corporation.

A process to apply zinc pyrithione to cotton with washable results was patented in the United States in 1984.
ZPT Zinc Pyrithione is used to prevent microbe growth in polyester.[13] Textiles with applied zinc pyrithione protect against odor-causing microorganisms.
ZPT Zinc Pyrithione is a common anti-dandruff ingredient that has been used for more than 60 years.

Many well-known brands of anti-dandruff shampoo products contain this ingredient, including Headshoulders and Clear, etc.
Shampoo for dandru, ZPT Zinc Pyrithione can inhibit Gram positive and negative bacteria and mold growth,Care hair Eectively, delay hair aging ,control white hair and hair loss generation.
ZPT Zinc Pyrithione is also used as a cosmetic preservative, oil, paint biocide.

ZPT Zinc Pyrithione has a strong killing power on fungi and bacteria so that it can eectively kill dandru fungus,playing a role in dandru.
ZPT Zinc Pyrithione is a preservative against bacteria, fungi, and yeast.
ZPT Zinc Pyrithione is unstable in light and in the presence of oxidizing agents.

ZPT Zinc Pyrithione is useful in gels, creams, heavy lotions, and talcum powder.
Reactions may lead to photosensitive eczema and actinic reticuloid syndrome.
ZPT Zinc Pyrithione is used as antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.

ZPT Zinc Pyrithione is directly cytotoxic and has antimicrobial eects.
ZPT Zinc Pyrithione is found in many shampoos (DHS-Zinc, Head and Shoulders) and should be applied for 5 minutes daily for 2 weeks.
ZPT Zinc Pyrithione is the active ingredient in several shampoos used to control dandru and seborrheic dermatitis and is also eective in the therapy of tinea versicolor.

ZPT Zinc Pyrithione remains unclear whether the benecial eects are caused by an antiproliferative or antimicrobial eect or both.
ZPT Zinc Pyrithione is substantive to the hair, allowing continued therapeutic eect after washing.

ZPT Zinc Pyrithione is a benecial compound owing to its antimicrobial properties and nds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, ZPT Zinc Pyrithione eectively targets dandru, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Safety Profile Of ZPT Zinc Pyrithione:
When heated to decomposition it emits very toxic fumes of NOx, SOx, and ZnO, is used as an anti- dandruff agent in shampoos.
The toxicity of the active substance zinc pyrithione has been investigated in standard laboratory tests with a number of aquatic organisms living in fresh water (the green alga Selenastrum capricornutum, the crustacean Daphnia magna, the fish rainbow trout (Oncorhynchus mykiss) and fathead minnow (Pimephales promelas)) and in seawater (the crustacean Mysidopsis bahia, the fish sheepshead minnow (Cyprinodon variegatus) and the oyster.

While generally safe for topical use, ZPT Zinc Pyrithione may cause mild side effects such as skin irritation, redness, or dryness, especially in individuals with sensitive skin.
Prolonged or excessive use can exacerbate these symptoms.
Additionally, some people may experience allergic reactions characterized by itching or swelling.

ZPT Zinc Pyrithione is advisable to perform a patch test before widespread application and discontinue use if adverse reactions occur.
Poison by ingestion, skin contact, intraperitoneal, and intravenous routes.
Moderately toxic by subcutaneous route, an experimental teratogen, experimental reproductive effects.