1-BROMO-4-IODOBENZENE, 98%

1-Bromo-4-Iodobenzene, 98% is a reagent used to prepare aminomethyl-piperidones which are potential DPPY-IV inhibitors and has antidiabetic ativities.
1-Bromo-4-Iodobenzene, 98% refers to a chemical compound with the formula C6H4BrI, containing both bromine and iodine atoms attached to a benzene ring in the para-position. 
1-Bromo-4-Iodobenzene, 98% is a high-purity chemical compound characterized by its molecular formula C6H4BrI, in which a bromine atom and an iodine atom are substituted on a benzene ring at opposite (para) positions.

CAS Number: 589-87-7
Molecular Formula: C6H4BrI
Molecular Weight: 282.9
EINECS Number: 209-662-7

Synonyms: 1-Bromo-4-iodobenzene, 589-87-7, 4-BROMOIODOBENZENE, p-Bromoiodobenzene, Benzene, 1-bromo-4-iodo-, p-Iodobromobenzene, 4-bromo-1-iodobenzene, 4-iodobromobenzene, p-Bromophenyl iodide, 4-bromophenyl iodide, MFCD00001051, 4-iodo-1-bromobenzene, 1-bromo-4-iodo-benzene, R9LDG2XS7C, NSC 8033, NSC-8033, EINECS 209-662-7, AI3-09032, DTXSID5060433, 1-Bromo-4-iodobenzene-[13C6], pBromoiodobenzene, pIodobromobenzene, NSC8033, pBromophenyl iodide, p-bromo iodobenzene, 4-bromo iodobenzene, 4-bromo-iodobenzene, 4-iodo bromobenzene, 4-iodo-bromobenzene, para-bromoiodobenzene, 4-bromo-iodo-benzene, Benzene, 1bromo4iodo, 1-bromo-4-iodobezene, 1-Iodo-4-Brombenzene, 1-iodo-4-bromobenzene, 1-bromo-4-iodo benzene, 1-iodo-4-bromo-benzene, 4-bromo-1-iodo-benzene, UNII-R9LDG2XS7C, 1-Bromo-4-iodobenzene-d4, SCHEMBL24146, 1-bromanyl-4-iodanyl-benzene, 1-Bromo-4-iodobenzene, 98%, DTXCID6042496, AC-174, MFCD30717990, AKOS000185502, CS-W008977, GS-3007, BP-13428, SY005124, SY099344, DB-027383, B0604, NS00034056, EN300-71276, A832097, J-504447, Z299596184, benzene,1-broMo-4-iodo-;1-BroMo-4-iodobenzene, 98% 25GR;1-Brom-4-iodobenzene;4-Bromoiodobenzene 99+%;4-BroMoiodobenzene, 97+%;4-BroMoiodoben;The broMine iodobenzene;4-Bromoiodobenzene p-Bromoiodobenzene

1-Bromo-4-Iodobenzene, 98% is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone. 
1-Bromo-4-Iodobenzene, 98% is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids).
Vapour pressure as a function of temperature for 1-Bromo-4-Iodobenzene, 98% has been studied using a diaphragm manometer and torsion mass-loss effusion.

The "98%" indicates its purity level, signifying that the product is composed of at least 98% of this specific compound, with impurities making up the remaining 2%.
The "98%" designation indicates that the compound has a high level of chemical purity, meaning that at least 98% of the material consists of 1-Bromo-4-Iodobenzene, while the remaining 2% consists of minimal impurities. 
This makes it highly suitable for precision applications, particularly in sensitive chemical reactions and advanced material synthesis.

The molecular formula C6H4BrI indicates the presence of one bromine atom, one iodine atom, and a benzene ring as its core structure, giving it a molecular weight of approximately 282.90 g/mol.
Typically, 1-Bromo-4-Iodobenzene, 98% exists as a crystalline solid, which can range in color from white to a pale yellow, depending on specific storage conditions and the level of residual impurities.
The melting point of 1-Bromo-4-Iodobenzene, 98% usually falls in the range of 62–64 °C, while its boiling point is around 250 °C, making it thermally stable under a wide range of conditions.

While it is insoluble in water, it readily dissolves in a variety of organic solvents such as acetone, diethyl ether, ethanol, and chloroform, which makes it versatile for organic synthesis applications.
1-Bromo-4-Iodobenzene, 98% is a specialized organic compound with the chemical formula C6H4BrI, where a benzene ring is functionalized with one bromine atom and one iodine atom located at para positions relative to each other. 
The "98%" purity label ensures that the product is of high quality, with only minimal impurities (2% or less), making it particularly suitable for use in precision chemical applications, advanced research, and industrial processes requiring consistent performance and reliability. 

The dual halogen functionality of 1-Bromo-4-Iodobenzene, 98% makes it a versatile intermediate in organic synthesis, enabling a wide range of reactions and molecular designs.
The molecular structure of 1-Bromo-4-Iodobenzene, 98% consists of a benzene ring with bromine and iodine substituents positioned opposite to each other, giving it symmetrical properties. 
Its molecular formula, C6H4BrI, reflects this dual-halogen substitution, and its molecular weight is approximately 282.90 g/mol.

1-Bromo-4-Iodobenzene, 98% is widely employed as an intermediate in the synthesis of complex organic molecules, particularly those requiring halogenated aromatic rings as core structures.
It is a key starting material in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Stille reactions, which are essential for forming biaryl compounds and other multi-functionalized aromatic systems.

In the pharmaceutical industry, 1-Bromo-4-Iodobenzene, 98% is used as a precursor for designing molecules with potential therapeutic applications. 
Its halogen substitutions influence molecular reactivity, sterics, and electronic properties, enabling the creation of drug candidates with tailored activity and improved pharmacokinetics.
1-Bromo-4-Iodobenzene, 98% plays a crucial role in the development of advanced materials, such as liquid crystals for display technologies, semiconducting polymers for electronic devices, and other materials requiring halogenated aromatic structures for enhanced physical properties.

In academic and industrial research laboratories, 1-Bromo-4-Iodobenzene, 98% is often used to study the reactivity of halogenated benzenes and to develop new methodologies for halogen-exchange reactions, aromatic substitutions, or functional group transformations.
The combination of bromine and iodine groups allows selective chemical reactivity, where one halogen can be targeted for specific reactions while retaining the other for further functionalization. 
This makes it an ideal reagent for stepwise synthetic strategies.

Store the compound in an airtight container, away from moisture, direct sunlight, and heat sources, in a cool and dry place to ensure its stability and maintain its high purity level. 
A desiccator or a nitrogen-filled glovebox can be used for long-term storage.
Always handle this compound in a well-ventilated environment, such as a fume hood, to avoid inhalation of vapors or dust.

Personal protective equipment (PPE), including gloves, goggles, and a lab coat, should be worn to prevent contact with the skin or eyes. 
In case of exposure, follow proper safety protocols to minimize any risk.
1-Bromo-4-Iodobenzene, 98% is chemically stable under standard conditions but should not be exposed to oxidizing agents, strong acids, or high temperatures to avoid unwanted decomposition or reactions.

1-Bromo-4-Iodobenzene, 98% is a critical reagent in constructing complex organic frameworks through palladium-catalyzed cross-coupling reactions like Suzuki-Miyaura, Stille, Heck, and Sonogashira reactions. 
These methodologies are essential for forming carbon-carbon and carbon-heteroatom bonds in high-value molecules.
Its halogen atoms act as functional handles for stepwise chemical modifications, enabling the synthesis of multi-functionalized aromatic systems critical in drug discovery, agrochemical development, and material research.

In drug development, 1-Bromo-4-Iodobenzene, 98% is often employed as a precursor for designing pharmacologically active molecules. 
The dual halogenation influences the molecular properties, such as binding affinity, metabolic stability, and solubility, crucial for therapeutic activity.
1-Bromo-4-Iodobenzene, 98% plays a pivotal role in synthesizing intermediates for cancer therapeutics, antimicrobial agents, and anti-inflammatory drugs.

1-Bromo-4-Iodobenzene, 98% contributes to the design of advanced functional materials, such as conducting polymers, liquid crystals, and organic light-emitting diodes (OLEDs), where halogenated aromatic structures enhance physical properties like thermal stability, conductivity, and optical characteristics.
1-Bromo-4-Iodobenzene, 98% is used in the development of halogen-rich molecules for applications in semiconductors and photovoltaic devices, where its reactivity allows precise tailoring of electronic and optical features.

In academic and industrial laboratories, 1-Bromo-4-Iodobenzene, 98% is a model compound for studying aromatic halogenation, regioselectivity in reactions, and advanced coupling strategies.
Researchers utilize it to explore new methodologies for halogen-metal exchange and to develop innovative catalysts and reaction conditions.

1-Bromo-4-Iodobenzene, 98% is used in synthesizing halogenated derivatives for electronic materials, including insulators, thin-film transistors, and energy storage devices. 
1-Bromo-4-Iodobenzene, 98%s role in creating unique halogen-rich frameworks aids in optimizing device performance.

Melting point: 89-91 °C(lit.)
Boiling point: 120-122 °C14 mm Hg(lit.)
Density: 2.2236 (rough estimate)
refractive index: 1.6618 (estimate)
Flash point: 120-122°C/14mm
storage temp.: Store below +30°C.
solubility: 0.008g/l
form: Crystalline Powder, Crystals or Needles
color: White to brown
Water Solubility: Insoluble in water.
Sensitive: Light Sensitive

1-Bromo-4-Iodobenzene, 98% is as raw material, by diazotization, iodo-synthesis of bromo iodobenzene. 
Preferred synthesis conditions: firstly 0.02mol parabromoaniline is dissolved in a mass fraction of 20% sulfuric acid medium, then reacts with 0.021molNaNO2 to generate bromophenyl diazonium sulfate at-10℃, and then chloroform and 0.021molKI is added into solution to process iodination reaction, after simple treatment bromo-iodobenzene crude product (which the bromo-iodobenzene HPLC purity 98.4%) is obtained, total yield after purification is 80%, increases by 15% than before improved. 

1-Bromo-4-Iodobenzene, 98% processes structural characterization by IR and 1HNMR. 
The improved method can greatly improve the purity of the crude product, this avoids the trouble of going through the column, this method is safe and easy to operate, easy to control the process, cost is lower, it is more suitable for the preparation of 1-Bromo-4-iodobenzene.
1-Bromo-4-Iodobenzene, 98% is typically a solid at room temperature, with a crystalline texture and a color that can vary from white to pale yellow, depending on the presence of trace impurities or storage conditions.

1-Bromo-4-Iodobenzene, 98% exhibits a melting point between 62–64 °C, which is relatively low for aromatic halides, and a boiling point around 250 °C, demonstrating excellent thermal stability under standard laboratory and industrial conditions.
While it is insoluble in water, 1-Bromo-4-Iodobenzene, 98% dissolves readily in a variety of organic solvents, such as chloroform, ethanol, diethyl ether, and acetone. 
This solubility in nonpolar and polar aprotic solvents makes it convenient to handle in organic synthesis and facilitates its use in complex reaction setups.

1-Bromo-4-Iodobenzene, 98% is a highly specialized compound used in the fields of organic chemistry, material science, and pharmaceutical research due to its unique dual-halogenated aromatic structure. 
Its molecular formula, C6H4BrI, represents a benzene ring functionalized with bromine and iodine atoms at para positions, which gives it symmetrical and predictable reactivity.
The "98%" designation guarantees high purity, ensuring the compound's consistent performance in sophisticated chemical reactions and industrial applications.

The molecule is designed with a bromine atom (Br) and an iodine atom (I) bonded directly to the benzene ring, creating a para-disubstituted aromatic compound. 
This arrangement provides selective reactivity during chemical processes and opens the possibility for stepwise functionalization.
1-Bromo-4-Iodobenzene, 98%s molecular weight is 282.90 g/mol, and its structural formula is often depicted as a benzene ring with halogens at opposite ends, ensuring clarity in its representation for chemical modeling and synthesis.

Typically found as a crystalline solid, its color ranges from off-white to pale yellow, depending on storage conditions and trace impurities.
With a melting point of approximately 62–64 °C and a boiling point around 250 °C, this compound demonstrates stability under standard reaction conditions.
1-Bromo-4-Iodobenzene, 98%s thermal properties make it easy to manipulate in laboratory and industrial settings without degradation.

1-Bromo-4-Iodobenzene, 98%s relatively high density, a result of halogen substitutions, is characteristic of brominated and iodinated aromatic compounds, contributing to its distinct handling and application requirements.
Insoluble in water, 1-Bromo-4-Iodobenzene, 98% dissolves effectively in organic solvents such as dichloromethane, acetone, and toluene, making it highly versatile in various chemical environments.
The dual-halogen substitution offers selective reactivity, where either bromine or iodine can be activated independently in reactions like nucleophilic substitutions, coupling reactions, or halogen-metal exchange.

Store in a cool, dry place away from moisture and light to maintain its purity and stability. 
Airtight containers are recommended, with inert atmosphere storage (e.g., nitrogen) for extended periods.
Personal protective equipment (PPE), including gloves, safety goggles, and a lab coat, should be worn during handling.

In case of skin or eye contact, wash thoroughly with water and seek medical advice if irritation persists.
1-Bromo-4-Iodobenzene, 98% is chemically stable under standard conditions but should be protected from extreme heat and strong oxidizing environments to avoid decomposition or hazardous reactions.

Uses Of 1-Bromo-4-Iodobenzene, 98%:
1-Bromo-4-Iodobenzene, 98% is increasingly used in the development of nanotechnology and electronic materials, particularly in the creation of functionalized materials with enhanced properties for use in advanced electronic devices. 
The presence of halogens such as bromine and iodine can increase the thermal stability, electrical conductivity, and optical properties of these materials. 
This makes them suitable for a wide range of applications in fields like organic photovoltaics, flexible electronics, and printed circuit boards.

Due to the high reactivity of the iodine and bromine atoms, 1-Bromo-4-Iodobenzene, 98% is often used in the preparation of nano-sized materials or quantum dots, which are employed in cutting-edge research related to electronic components and nanoelectronics.
1-Bromo-4-Iodobenzene, 98% is used for organic synthesis.
1-Bromo-4-Iodobenzene, 98% is used as substrate for copper-free Sonogashira coupling reaction in aqueous acetone.

1-Bromo-4-Iodobenzene, 98% is used as a building block in the synthesis of complex organic molecules.
Common in Suzuki-Miyaura and Stille cross-coupling reactions to create biaryl compounds or other derivatives.
Intermediate in the production of pharmaceuticals, particularly in medicinal chemistry to design bioactive molecules.

Precursor for the synthesis of functional materials, including liquid crystals and conducting polymers.
1-Bromo-4-Iodobenzene, 98% is used in academic and industrial research to study halogenated aromatic compounds.
The bromine and iodine groups provide selective reactivity, allowing chemists to tailor reactions for specific outcomes.

1-Bromo-4-Iodobenzene, 98% is widely utilized as a versatile building block in organic chemistry, where it acts as a halogenated intermediate for the preparation of more complex molecular structures.
Its bromine and iodine substituents allow for selective reactivity, making it highly useful in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura or Stille coupling processes. 
These reactions enable the formation of biaryl compounds, which are essential in pharmaceuticals, agrochemicals, and advanced material applications.

In the pharmaceutical sector, 1-Bromo-4-Iodobenzene, 98% serves as a critical intermediate for synthesizing biologically active compounds. 
Its unique halogen substitution pattern can introduce electronic and steric effects that are crucial for the pharmacological activity of target molecules.
1-Bromo-4-Iodobenzene, 98% finds application in the development of functional materials, such as liquid crystals used in display technologies or polymers with enhanced electrical or optical properties. 

The presence of bromine and iodine enhances the reactivity and tuning of the material properties during synthesis.
1-Bromo-4-Iodobenzene, 98% is frequently employed in academic and industrial research settings as a model molecule to explore halogenated aromatic chemistry, as well as in the study of reaction mechanisms involving aryl halides.
Its bromine and iodine groups allow for controlled reactivity, where one halogen can be selectively replaced or retained depending on the reaction conditions. 

This makes it ideal for designing stepwise synthetic pathways.
1-Bromo-4-Iodobenzene, 98% plays a crucial role in several key organic reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. 
In cross-coupling reactions, 1-Bromo-4-Iodobenzene, 98% serves as a starting material for various types of reactions such as Suzuki-Miyaura, Stille, Heck, and Sonogashira coupling. 

These reactions, which are often catalyzed by palladium or other transition metals, allow the creation of complex organic molecules with precise molecular structures. 
The presence of both bromine and iodine atoms enables the selective activation of one halogen at a time, facilitating a controlled process for creating functionalized aromatic compounds. 
In these reactions, 1-Bromo-4-Iodobenzene, 98% is particularly valuable for the synthesis of biaryl compounds, which are used in a range of chemical applications including pharmaceuticals, agrochemicals, and materials.

The selective functionalization enabled by the different halogen atoms in 1-Bromo-4-Iodobenzene, 98% is particularly important. 
The iodine atom is typically more reactive and can be selectively replaced in reactions that are sensitive to the iodine-bromine distinction. This allows chemists to selectively introduce other functional groups, making 1-Bromo-4-Iodobenzene, 98% a versatile intermediate in multi-step organic synthesis.

In pharmaceutical research, 1-Bromo-4-Iodobenzene, 98% is utilized as an intermediate in the synthesis of bioactive compounds. 
The halogen atoms influence the electronic properties of the compound, which can be fine-tuned to improve the interaction with biological targets. 
This makes it a useful precursor for designing drugs with improved potency, selectivity, and bioavailability. 

1-Bromo-4-Iodobenzene, 98% is particularly used in the development of anti-cancer, anti-inflammatory, and antimicrobial agents, where halogenation can enhance the pharmacological properties of drug candidates.
The halogens, iodine and bromine, both increase the lipophilicity of the molecules, which can improve the ability of these drugs to penetrate cell membranes and reach their target sites. 
Additionally, they can enhance the molecular stability and half-life of drugs, ensuring their effectiveness over time. 

1-Bromo-4-Iodobenzene, 98%, in drug development, halogenation often contributes to improving the metabolic stability of pharmaceuticals, making them more resistant to breakdown by enzymes.
In material science, 1-Bromo-4-Iodobenzene, 98% is used as a precursor for the synthesis of functional materials such as organic semiconductors, conductive polymers, and liquid crystals. 
These materials have a variety of applications in the field of organic electronics. 

For example, 1-Bromo-4-Iodobenzene, 98% can be used in the development of organic light-emitting diodes (OLEDs), which are essential for display technologies, as well as thin-film transistors (TFTs) used in flexible electronic devices.
The iodine and bromine atoms in 1-Bromo-4-Iodobenzene, 98% can also influence the electronic properties of these materials, improving their efficiency and performance. 
As these materials are increasingly used in next-generation solar cells, light-emitting diodes, and other electronic devices, the versatility of 1-Bromo-4-Iodobenzene as a synthetic building block plays a significant role in advancing the field of organic electronics.

In the realm of chemical research, 1-Bromo-4-Iodobenzene, 98% is used extensively as a model compound to study various aspects of halogen chemistry, including halogen-metal exchange reactions and reactivity in cross-coupling processes. 
The distinct nature of bromine and iodine halogens allows for the development of new catalytic systems and methods for selective halogenation. 
This is crucial for improving the efficiency and selectivity of reactions that involve halogenated compounds.

Researchers also use this compound to optimize reaction conditions for complex organic reactions. 
The ability to manipulate the reactivity of 1-Bromo-4-Iodobenzene, 98% allows for a deeper understanding of reaction mechanisms and catalyst development, which can be applied to a wide range of reactions in organic chemistry.

Safety Profile Of 1-Bromo-4-Iodobenzene, 98%:
1-Bromo-4-Iodobenzene, 98% should be stored in a tightly sealed container, away from moisture, direct sunlight, and sources of heat, in a cool and dry location to maintain its stability and purity over time.
It is essential to handle this compound in a well-ventilated environment, such as a fume hood, to avoid inhalation of any dust or vapors. 
Proper personal protective equipment (PPE), including gloves, safety goggles, and lab coats, should be worn to minimize the risk of exposure to the skin or eyes.