PRODUCTS

2,4-DICHLOROTOLUENE

2,4-Dichlorotoluene is also employed in specialty chemical production involving resins, advanced materials, and custom organic synthesis.
2,4-Dichlorotoluene is used primarily as an intermediate in the manufacture of dyes, pigments, pharmaceuticals, crop protection chemicals, and numerous specialty organic compounds.

CAS Number: 95-73-8
EC Number: 202-450-5
Molecular Formula: C₇H₆Cl₂
Molecular Weight: 161.03 g/mol

SYNONYMS:
2,4-DICHLOROTOLUENE, 95-73-8, 2,4-Dichloro-1-methylbenzene, Benzene, 2,4-dichloro-1-methyl-, Toluene, 2,4-dichloro-, DTXSID5040702, 3S32N6LG3X, NSC-8764, DTXCID3020702, RefChem:82400, 202-445-8, 2,4-dichloro-1-methyl-benzene, MFCD00000583, 2 pound not4-Dichlorotoluene, HSDB 2567, NSC 8764, EINECS 202-445-8, 2,4-dichloromethylbenzene, BRN 1931691, UNII-3S32N6LG3X, 2,4-DCT, 2,4-Diclorotoluene, 4,6-dichlorotoluene, 2,4-dichloro-methylbenzene, EC 202-445-8, SCHEMBL28352, SCHEMBL40603, 2,4-Dichlorotoluene, 99%, SCHEMBL152426, Benzene,4-dichloro-1-methyl-, SCHEMBL2006396, SCHEMBL2088340, SCHEMBL2088341, SCHEMBL2347510, SCHEMBL27956761, SCHEMBL29351078, CHEBI:81651, NSC8764, 2,4-Dichloro-1-methylbenzene #, Tox21_302123, SBB061465, AKOS000121198, CAS-95-73-8, MSK005008-1000M, NCGC00164064-01, NCGC00255577-01, PS-11943, DB-024296, NSC 8764; 2,4-dichloro-1-methylbenzene, D0419, NS00002540, ST50406573, EN300-21594, C18300, F046773, 2,4-Dichlorotoluene Solution in Methanol, 1000ug/mL, Q27155532, F0001-2279, InChI=1/C7H6Cl2/c1-5-2-3-6(8)4-7(5)9/h2-4H,1H, 2,4-Dichlorotoluene, 1,3-Dichloro-4-methylbenzene, 2,4-DCT, 2,4-Dichloromethylbenzene, 4-Methyl-1,3-dichlorobenzene, 1,3-Dichloro-4-methylbenzene, 2,4-Dichloro-1-methylbenzene, 2,4-DCT;2,4-dichloro-1-methylbenzene;2,4-Dichlortoluol;4-DCT;2.4-Dichloroto;2,4-Dichlorotoluol;2,4-Dichlortoluene;2,4-DICHLORO TOLUNE;2,4-dichloro-toluen;2,4-DICHLOROTOLUENE, Benzene,2,4-dichloro-1-methyl-;Toluene,2,4-dichloro-;2,4-Dichloro-1-methylbenzene;2,4-Dichlorotoluene;1,3-Dichloro-4-methylbenzene;NSC 8764, 2,4-dichloro-1-methylbenzene, 2,4-dichlorotoluene, benzene, 2,4-dichloro-1-methyl, toluene, 2,4-dichloro, 2,4-dichloro-1-methyl-benzene, unii-3s32n6lg3x, 2,4-dichloromethylbenzene, 2,4-dct, 2,4-diclorotoluene, 4,6-dichlorotoluene, 2,4-dichloro-toluen

2,4-dichlorotoluene is a clear, colorless liquid.
2,4-Dichlorotoluene is a dichlorobenzene.
2,4-Dichlorotoluene is a chlorinated aromatic hydrocarbon consisting of a methyl-substituted benzene ring with chlorine atoms at the 2- and 4-positions.

2,4-dichlorotoluene is a clear, colorless liquid.
2,4-Dichlorotoluene is a dichlorobenzene.
2,4-Dichlorotoluene was used as an oxidant and a solvent during anaerobic catalytic oxidation of secondary alcohols by using an in situ (N-heterocyclic carbene)-Ni(0) system.

2,4-Dichlorotoluene was used as growth supplement in the culture media of Ralstonia sp. strain PS12.
2,4-Dichlorotoluene is a dichlorobenzene.

USES and APPLICATIONS of 2,4-DICHLOROTOLUENE:
2,4-Dichlorotoluene is primarily used as an industrial intermediate in the manufacture of dyes, pigments, pharmaceuticals, agrochemicals, and specialty organic chemicals.
Due to the presence of both methyl and chlorine substituents, 2,4-Dichlorotoluene exhibits useful chemical reactivity for electrophilic substitution, oxidation, and nucleophilic substitution reactions, making it an important building block in organic synthesis.

2,4-Dichlorotoluene is generally handled in closed industrial systems because of its toxicity and potential environmental hazards.
Although 2,4-Dichlorotoluene has limited direct consumer applications, it remains a valuable intermediate in fine chemical and specialty chemical production.
2,4-Dichlorotoluene is used primarily as an intermediate in the manufacture of dyes, pigments, pharmaceuticals, crop protection chemicals, and numerous specialty organic compounds.

2,4-Dichlorotoluene's chlorinated aromatic structure provides an excellent starting material for synthesizing more complex molecules through oxidation, amination, nitration, halogenation, and catalytic substitution reactions.
2,4-Dichlorotoluene serves as a feedstock for the production of chlorinated benzoic acids, aromatic amines, herbicide intermediates, and pharmaceutical building blocks.

2,4-Dichlorotoluene is widely utilized in fine chemical manufacturing where selective substitution on the aromatic ring is required to obtain high-value specialty chemicals.
In research laboratories, 2,4-dichlorotoluene functions as a reference compound and synthetic intermediate for developing new catalysts, reaction pathways, and aromatic derivatives.

2,4-Dichlorotoluene is also employed in specialty chemical production involving resins, advanced materials, and custom organic synthesis.
Although its direct use as a commercial solvent is relatively limited compared with other aromatic hydrocarbons, 2,4-Dichlorotoluene may be used in certain specialized industrial formulations where chlorinated aromatic solvents provide desirable solvency and chemical stability.
2,4-Dichlorotoluene was used as an oxidant and a solvent during anaerobic catalytic oxidation of secondary alcohols by using an in situ (N-heterocyclic carbene)-Ni(0) system.

2,4-Dichlorotoluene was used as growth supplement in the culture media of Ralstonia sp. strain PS12.
2,4-Dichlorotoluene was used to develop a sensitive method based on solid-phase microextraction followed by gas chromatography-tandem mass spectrometry for the analysis of chlorotoluenes in water samples.

BENEFITS of 2,4-DICHLOROTOLUENE:
2,4-Dichlorotoluene offers several technical advantages in industrial chemistry:
Valuable intermediate for specialty organic synthesis
Excellent precursor for dyes and pigments
Important raw material for pharmaceutical intermediates
Useful building block for agrochemical manufacturing
High chemical stability during storage
Good thermal stability under normal processing conditions
Compatible with numerous organic solvents
Suitable for selective aromatic substitution reactions
Useful feedstock for chlorinated aromatic derivatives
Moderate volatility allows controlled industrial processing
High purity grades are commercially available
2,4-Dichlorotoluene supports production of numerous value-added specialty chemicals

CHARACTERISTICS of 2,4-DICHLOROTOLUENE:
Chlorinated aromatic hydrocarbon
Methyl-substituted benzene derivative
Colorless to pale yellow liquid
Mild aromatic odor
Combustible liquid
Low water solubility
Good organic solvent compatibility
Moderate lipophilicity
Chemically stable
Reactive toward electrophilic substitution reactions
Industrial chemical intermediate
High boiling aromatic compound
Suitable for fine chemical synthesis
Important precursor for chlorinated aromatic products

PROPERTIES of 2,4-DICHLOROTOLUENE:
2,4-Dichlorotoluene is a chemically stable chlorinated aromatic compound possessing both electron-withdrawing chlorine atoms and an electron-donating methyl group.
This combination provides balanced reactivity, allowing 2,4-Dichlorotoluene to undergo a wide variety of industrial organic synthesis reactions.
Compared with toluene, chlorination increases its density, boiling point, and chemical resistance while reducing its water solubility.

2,4-Dichlorotoluene demonstrates excellent compatibility with many nonpolar organic solvents and remains stable during storage under recommended conditions.
2,4-Dichlorotoluene exhibits relatively low volatility compared with lighter aromatic hydrocarbons, allowing improved process control during chemical manufacturing.

The aromatic ring serves as an excellent platform for further chlorination, nitration, sulfonation, oxidation, and substitution reactions, making 2,4-dichlorotoluene an important precursor for numerous value-added chemical products.

Because of its hydrophobic nature and relatively high partition coefficient, 2,4-Dichlorotoluene preferentially distributes into organic phases rather than aqueous environments.
This property contributes both to 2,4-Dichlorotoluene's usefulness in organic synthesis and to the need for careful environmental management.

PREPARATION of 2,4-DICHLOROTOLUENE:
2,4-Dichlorotoluene is synthesized by diazotization and chlorination with 2,4-diaminotoluene as raw material.
First, hydrochloric acid and water into the reaction pot, heated to 50°C, stirring under the dissolution of 2,4-diaminotoluene, then hydrochloric acid and cuprous chloride into the pot, the 1% sodium nitrite solution evenly added, the temperature is maintained at about 60°C, resting stratification, the lower layer of crude product washed with water to neutral, add alkali to alkaline, and then water to remove the alkali, divided 2,4-dichlorotoluene crude product, water distillation of finished products.

CHEMICAL PROPERTIES of 2,4-DICHLOROTOLUENE:
2,4-Dichlorotoluene is a clear colorless liquid that is insoluble in water but can be mixed with ethanol, ether, and benzene.
2,4-Dichlorotoluene is primarily used as a pesticide and pharmaceutical intermediate, but also serves as a solvent.

PHYSICAL and CHEMICAL PROPERTIES of 2,4-DICHLOROTOLUENE:
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild aromatic, chlorinated odor
Physical State: Liquid at room temperature
Molecular Formula: C₇H₆Cl₂
Molecular Weight: 161.03 g/mol
Density: Approximately 1.24–1.25 g/cm³ (20°C)
Melting Point: Approximately −14°C
Boiling Point: Approximately 196–198°C

Flash Point: Approximately 79–82°C (closed cup)
Autoignition Temperature: Approximately 520°C
Vapor Pressure: Approximately 0.5–0.7 hPa (20°C)
Vapor Density: Approximately 5.6 (air = 1)
Relative Density: Approximately 1.25
Refractive Index: Approximately 1.545
Water Solubility: Very slightly soluble (less than 200 mg/L at 25°C)
Solubility: Soluble in ethanol, benzene, toluene, ether, chloroform, acetone, and many organic solvents

Log Kow: Approximately 4.0
Partition Coefficient: Moderately lipophilic
Viscosity: Low
Surface Tension: Moderate
Volatility: Low to moderate
Chemical Stability: Stable under normal storage conditions
Reactivity: Reacts with strong oxidizing agents; participates in aromatic substitution and oxidation reactions
Flammability: Combustible liquid
Explosion Hazard: Vapors may form combustible mixtures with air at elevated temperatures
Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, and chlorinated organic vapors

Corrosivity: Not corrosive under normal conditions
Biodegradability: Slow to moderate
Environmental Mobility: Moderate; tends to adsorb to soils containing organic matter
Bioaccumulation Potential: Moderate due to its hydrophobic character
Molecular Weight: 161.03 g/mol
XLogP3: 4.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 0

Exact Mass: 159.9846556 Da
Monoisotopic Mass: 159.9846556 Da
Topological Polar Surface Area: 0 Å²
Heavy Atom Count: 9
Formal Charge: 0
Complexity: 92.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical Name: 2,4-Dichlorotoluene
Common Name: 2,4-DCT
CAS Number: 95-73-8
EC Number: 202-450-5
Molecular Formula: C₇H₆Cl₂
Molecular Weight: 161.03 g/mol
Linear Formula: CH3C6H3Cl2

CAS Number: 95-73-8
Molecular Weight: 161.03
UNSPSC Code: 12352100
NACRES: NA.22
PubChem Substance ID: 24848696
EC Number: 202-445-8
Beilstein/REAXYS Number: 1931691
MDL number: MFCD00000583
Assay: 99%
Form: liquid

CBNumber: CB2854706
Molecular Formula: C7H6Cl2
Molecular Weight: 161.03
MDL Number: MFCD00000583
MOL File: 95-73-8.mol
Melting point: -14 °C
Boiling point: 200 °C (lit.)
Density: 1.246 g/mL at 25 °C (lit.)
vapor pressure: 4 hPa (50 °C)
refractive index: n20/D 1.546(lit.)

Flash point: 175 °F
storage temp.: Store below +30°C.
form: Liquid
color: Clear colorless
Water Solubility: immiscible
BRN: 1931691
Henry's Law Constant: 2.7×10-3 mol/(m3Pa) at 25℃, Schwardt et al. (2021)
InChI: 1S/C7H6Cl2/c1-5-2-3-6(8)4-7(5)9/h2-4H,1H3
InChIKey: FUNUTBJJKQIVSY-UHFFFAOYSA-N

SMILES: Cc1ccc(Cl)cc1Cl
CAS DataBase Reference: 95-73-8(CAS DataBase Reference)
EWG's Food Scores: 2
FDA UNII: 3S32N6LG3X
NIST Chemistry Reference: Benzene, 2,4-dichloro-1-methyl-(95-73-8)
EPA Substance Registry System: 2,4-Dichlorotoluene (95-73-8)
UNSPSC Code: 12352100
NACRES: NA.22
Physical state: liquid
Colour: No data available

Odour: No data available
Melting point: No data available
Boiling point/boiling range: 200 °C
Method: lit.
Flammability: No data available
Upper explosion limit / Upper flammability limit: No data available
Lower explosion limit / Lower flammability limit: No data available
Flash point: 79 °C
Autoignition temperature: > 450 °C
Decomposition temperature: No data available

pH: No data available
Viscosity, dynamic: No data available
Viscosity, kinematic: No data available
Flow time: No data available
Water solubility: No data available
Partition coefficient: noctanol/water: No data available
Vapour pressure: No data available
Relative density: No data available
Density: 1,246 g/mL (25 °C)
Method: lit.
Relative vapour density: No data available
Explosives: Not classified as explosive.

Oxidizing properties: none
Burning rate: No data available
Evaporation rate: No data available
Molecular weight: 161,03 g/mol
Molecular Formula / Molecular Weight: C7H6Cl2 = 161.03
Physical State (20 deg.C): Liquid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN: 95-73-8
Reaxys Registry Number: 1931691
PubChem Substance ID: 87567099
SDBS (AIST Spectral DB): 2182
MDL Number: MFCD00000583

Physical state : liquid
Colour : No data available
Odour : No data available
Melting point : No data available
Boiling point/boiling range : 200 °C
Method: lit.
Flammability : No data available
Upper explosion limit /
Upper flammability limit: No data available
Lower explosion limit / Lower flammability limit: No data available

Flash point : 79 °C
Autoignition temperature : > 450 °C
Decomposition temperature: No data available
pH : No data available
Viscosity, dynamic : No data available
Viscosity, kinematic : No data available
Flow time : No data available
Water solubility : No data available
Partition coefficient: noctanol/water : No data available

Vapour pressure : No data available
Relative density : No data available
Density : 1,246 g/mL (25 °C)
Method: lit.
Relative vapour density : No data available
Explosives : Not classified as explosive.
Oxidizing properties : none
Burning rate : No data available
Evaporation rate : No data available
Molecular weight : 161,03 g/mol

CAS Min %: 98.5
CAS Max %: 100.0
Melting Point: -14.0°C
Color: Colorless
Density: 1.2400g/mL
Boiling Point: 200.0°C
Flash Point: 79°C
Infrared Spectrum: Authentic
Assay Percent Range: 98.5% min. (GC)
Refractive Index: 1.5450 to 1.5470
Linear Formula: CH3C6H3Cl2
Beilstein: 05, 295

Specific Gravity: 1.24
Solubility Information: Solubility in water: immiscible.
Other solubilities: soluble in alcohol,ether and acetone
Formula Weight: 161.03
Percent Purity: 99%
Physical Form: Liquid
Chemical Name or Material: 2, 4-Dichlorotoluene, 99%
CAS: 95-73-8
Molecular Formula: C7H6Cl2
Molecular Weight (g/mol): 161.03

MDL Number: MFCD00000583
InChI Key: FUNUTBJJKQIVSY-UHFFFAOYSA-N
PubChem CID: 7254
ChEBI: CHEBI:81651
IUPAC Name: 2,4-dichloro-1-methylbenzene
SMILES: CC1=C(C=C(C=C1)Cl)Cl
Linear Formula: C7H6Cl2
CAS Number: 95-73-8
Molecular Weight: 161.03
MDL number: MFCD00000583
Physical state: liquid
Colour: No data available

Viscosity, dynamic: No data available
Viscosity, kinematic: No data available
Flow time: No data available
Water solubility: No data available
Partition coefficient: noctanol/water: No data available
Vapour pressure: No data available
Relative density: No data available
Density: 1,246 g/mL (25 °C)
Method: lit.
Relative vapour density: No data available
Explosives: Not classified as explosive.
Oxidizing properties: none
Burning rate: No data available
Evaporation rate: No data available
Molecular weight: 161,03 g/mol

FIRST AID MEASURES of 2,4-DICHLOROTOLUENE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of 2,4-DICHLOROTOLUENE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of 2,4-DICHLOROTOLUENE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of 2,4-DICHLOROTOLUENE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of 2,4-DICHLOROTOLUENE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of 2,4-DICHLOROTOLUENE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available