2-Dimethylaminoethanol is used as pharmaceutical raw materials, intermediates for the manufacture of dyes, fiber treatment agents, anti-corrosion additives, etc.
2-Dimethylaminoethanol can be used as water-soluble paint base materials, synthetic resin solvents, etc.
2-Dimethylaminoethanol is used as dye intermediates, fabric dye assistants and preservatives, and also used in the pharmaceutical industry.
CAS Number: 108-01-0
EC Number: 203-542-8
MDL number: MFCD00002846
Linear Formula: (CH3)2NCH2CH2OH
Molecular Formula: C₄H₁₁NO
Molecular Weight: 89.14 g/mol
SYNONYMS:
2-(Dimethylamino)ethan-1-ol, Deanol, Dimethyl ethanolamine, Dimethylaminoethanol, N,N-Dimethylaminoethanol, N,N-Dimethylethanolamine, N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, Jeffcat DMEA, (2-Hydroxyethyl)dimethylamine, (CH3)2NCH2CH2OH, (Dimethylamino)ethanol, (N,N-dimethylamino)ethanol, .beta.-(dimethylamino)ethanol, .beta.-dimethylaminoethyl alcohol, .beta.-hydroxyethyldimethylamine, 2-(Dimethylamino)-1-ethanol, 2-(Dimethylamino)ethanol, 2-(N,N-Dimethylamino)ethanol, 2-(dimethylamino)ethyl alcohol, 2-dimethylaminoethanol, 67-48-1, Amietol M 21, Bimanol, DMAE, DMEA, Dabco DMEA, Deanol, Dimethyl(2-hydroxyethyl)amine, Dimethyl(hydroxyethyl)amine, Dimethylaethanolamin, Dimethylaminoaethanol, Dimethylethanolamine, Dimethylmonoethanolamine, Ethanol, 2-(dimethylamino)-, Kalpur P, Liparon, N,N'-Dimethylethanolamine, N,N-Dimethyl(2-hydroxyethyl)amine, N,N-Dimethyl-2-aminoethanol, N,N-Dimethyl-N-(2-hydroxyethyl)amine, N,N-Dimethyl-N-(«beta»-hydroxyethyl)amine, N,N-Dimethyl-N-(«beta»-hydroxyethyl)amine, N,N-Dimethyl-«beta»-hydroxyethylamine, N,N-Dimethyl-«beta»-hydroxyethylamine, N,N-Dimethylethanolamine, N,N-dimethyl-.beta.-hydroxyethylamine, N,N-dimethyl-2-hydroxyethylamine, N,N-dimethyl-N-(.beta.-hydroxyethyl)amine, N-(2-Hydroxyethyl)dimethylamine, N-(Dimethylamino)ethanol, NSC 2652, Norcholine, Propamine A, Tegoamin DMEA, Texacat DME, UN 2051, Varesal, ethanolamine, N,N-dimethyl-, «beta»-(Dimethylamino)ethanol, «beta»-(Dimethylamino)ethyl alcohol, «beta»-Hydroxyethyldimethylamine, «beta»-(Dimethylamino)ethanol, «beta»-(Dimethylamino)ethyl alcohol, «beta»-Hydroxyethyldimethylamine, 2-(dimethylamino)ethanol, N,n-dimethylethanolamine, 108-01-0, Dimethylaminoethanol, Dimethylethanolamine, 2-dimethylaminoethanol, 2-dimethylamino ethanol, n,n-dimethylethanolamine, deanol, dimethylaminoethanol, dimethylethanolamine, norcholine, dmae, dmea, bimanol, liparon, N,N-Dimethyl-2-hydroxyethylamine, 2-Dimethylaminoethanol, DMAE, Dimethylaminoethanol, N,N-Dimethylaminoethanol, 2-Hydroxy-N,N-dimethylethylamine, Dimethylamino-2-ethanol, Dimethylaminoethanolum, 2-(Dimethylamino)ethanol, (2-Hydroxyethyl)dimethylamine, (Dimethylamino)ethanol, (N,N-Dimethylamino)ethanol, 2-(Dimethylamino)ethanol, 2-(Dimethylamino)ethyl alcohol, 2-(N,N-Dimethylamino)ethanol, Amietol M 21, Aminoalcohol 2mabs, Bimanol, DMAE, DMEA, Dabco DMEA, Deanol, DeuAdd MA 95, Dimethol, Dimethyl(2-hydroxyethyl)amine, Dimethyl(hydroxyethyl)amine, Dimethylethanolamine, Dimethylmonoethanolamine, Jeffcat DMEA, Kalpur P, Lupragen N 101, MA 95, N,N-Dimethyl(2-hydroxyethyl)amine, N,N-Dimethyl-2-aminoethanol, N,N-Dimethyl-2-ethanolamine, N,N-Dimethyl-N-(ß-hydroxyethyl)amine, N,N-Dimethyl-ß-hydroxyethylamine, N,N-Dimethylethanolamine, N-(2-Hydroxyethyl)-N,N-dimethylamine, N-(2-Hydroxyethyl)dimethylamine, NSC 2652, Niax DMEA, Norcholine, PC CAT DMEA, Propamine A, Rexolin, T 80, Tegoamin DMEA, Texacat DME, Texacat DMEA, Thancat DME, ß-(Dimethylamino)ethanol, ß-Dimethylaminoethyl alcohol, ß-Hydroxyethyldimethylamine, N,N Dimethylethanolamine, 2-Dimethylaminoethanol, Dimethyl MEA, DMEA, DMAE, DMEOA, Deanol, (2-Hydroxyethyl)dimethylamine, 2-(Dimethylamino)-1-ethanol, 2-(N,N-Dimethylamino)ethanol, 2-Dimethylaminoethanol, 2-Dwumetyloaminoetanolu [Polish], Amietol M 21, Bimanol, DMAE, DMEA, Deanol, Dimethyl(2-hydroxyethyl)amine, Dimethyl(hydroxyethyl)amine, Dimethylaethanolamin [German], Dimethylaminoaethanol [German], Dimethylaminoethanol, Dimethylethanolamine, Dimethylmonoethanolamine, Ethanol, 2-(dimethylamino)-, Kalpur P, Liparon, N,N-Dimethyl-2-aminoethanol, N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethyl-N-(2-hydroxyethyl)amine, N,N-Dimethyl-N-(beta-hydroxyethyl)amine, N,N-Dimethylaminoethanol, N,N-Dimethylethanolamine, N-(2-Hydroxyethyl)dimethylamine, N-Dimethylaminoethanol, Norcholine, Propamine A, Texacat DME, Varesal, beta-Dimethylaminoethyl alcohol, beta-Hydroxyethyldimethylamine, [ChemIDplus] UN2051, UN2920, N,N-Dimethyl-2-aminoethanol, Deanol, Varesal, Bimanol, Ethanol, 2-(dimethylamino)-, β-(Dimethylamino)ethanol, β-(Dimethylamino)ethyl alcohol, β-Hydroxyethyldimethylamine, (Dimethylamino)ethanol, (2-Hydroxyethyl)dimethylamine, Dimethyl(hydroxyethyl)amine, Dimethyl(2-hydroxyethyl)amine, Dimethylethanolamine, Dimethylmonoethanolamine, DMAE, Kalpur P, Liparon, N-(2-Hydroxyethyl)dimethylamine, N,N-Dimethyl(2-hydroxyethyl)amine, N,N-Dimethyl-N-(β-hydroxyethyl)amine, N,N-Dimethyl-N-(2-hydroxyethyl)amine, N,N-Dimethylethanolamine, Norcholine, Propamine A, 2-(Dimethylamino)ethanol, 2-(N,N-Dimethylamino)ethanol, (CH3)2NCH2CH2OH, Amietol M 21, Dimethylaminoaethanol, N-(Dimethylamino)ethanol, 2-(Dimethylamino)-1-ethanol, Dimethylaethanolamin, UN 2051, N,N-Dimethyl-β-hydroxyethylamine, Dabco DMEA, N,N'-Dimethylethanolamine, Tegoamin DMEA, Texacat DME, DMEA, NSC 2652, 67-48-1, N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, Jeffcat DMEA, dimethylaminoethanol, DMAE, DMEA, deanol (substance), norcholine, amietol, M 21, n,n dimethyl 2 hydroxyethylamine, astyl, deanol, deanol acetamidobenzoate, 2-(Dimethylamino)ethanol, beta-(Dimethylamino)ethanol, 2-(Dimethylamino)ethyl alcohol, 2-(N,N-Dimethylamino)ethanol, Dimethyl(2-hydroxyethyl)amine, Dimethy(hydroxyethl)amine, Dimethylethanolamine, N,N-Dimethyl(2-hydroxyethyl)amine, N,N-Dimethyl-beta-hydroxyethylamine, N,N-Dimethylethanolamine, N,N-Dimethyl-N-(beta-hydroxyethyl)amine, Norcholine
2-Dimethylaminoethanol, also known as dimethylethanolamine, is a versatile organic compound with a unique dual-functional structure combining an alcohol group and a tertiary amine.
This colorless to pale yellow liquid, 2-Dimethylaminoethanol, characterized by a faint ammonia-like odor, is highly soluble in water and organic solvents.
Synthesized through the reaction of ethylene oxide with dimethylamine, 2-Dimethylaminoethanol serves as a critical intermediate in chemical manufacturing.
Its reactivity and ability to act as a pH adjuster, catalyst, or surfactant make 2-Dimethylaminoethanol indispensable in industries ranging from pharmaceuticals to coatings.
2-Dimethylaminoethanol exemplifies the synergy of functionality and adaptability in industrial chemistry.
2-Dimethylaminoethanol's role in enhancing product performance—from durable coatings to advanced pharmaceuticals—underscores its irreplaceable value.
As industries prioritize sustainability, innovations in 2-Dimethylaminoethanol recycling and greener synthesis methods will further solidify its position as a responsible choice for modern manufacturing.
With ongoing research into novel applications, 2-Dimethylaminoethanol continues to pave the way for efficient, high-performance solutions across global markets.
2-Dimethylaminoethanol is a clear, viscous liquid with an amine-like odor that is widely used in the water treatment industry as a polyurethane catalyst, as an intermediate in textile chemicals, ion exchange resins and emulsifying agents and also in a wide range of coatings applications.
2-Dimethylaminoethanol, with the chemical formula C4H11NO , is an organic compound that is a colorless to pale yellow transparent liquid at room temperature.
2-dimethylaminoethanol appears as a clear colorless liquid with a fishlike odor.
Flash point of 2-Dimethylaminoethanol is 105 °F.
2-Dimethylaminoethanol is less dense than water.
2-Dimethylaminoethanol's vapors heavier than air.
2-Dimethylaminoethanol is a tertiary amine that is ethanolamine having two N-methyl substituents.
2-Dimethylaminoethanol has a role as a radical scavenger and a curing agent.
2-Dimethylaminoethanol is a member of ethanolamines and a tertiary amine.
2-Dimethylaminoethanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).
2-Dimethylaminoethanol holds tertiary amine and primary alcohol groups as functional groups.
2-Dimethylaminoethanol is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
2-Dimethylaminoethanol is a colorless viscous liquid.
The bitartrate salt of 2-Dimethylaminoethanol, i.e. N,N-dimethylethanolamine bitartrate, is sold as a dietary supplement.
2-Dimethylaminoethanol is a white powder providing 37% DMAE.
2-Dimethylaminoethanol (DMAE), also known as deanol or dimethylethanolamine (DMEA), is an amino alcohol.
2-Dimethylaminoethanol is formed as the main product in the amination of ethylene glycol by dimethylamine on alumina supported copper in a continuous fixed-bed reactor.
2-Dimethylaminoethanol is considered a putative precursor of acetylcholine and has been extensively studied for its effects as a skin-firming and anti-wrinkle agent.
2-Dimethylaminoethanol has also been investigated for its organic additive properties, particularly in relation to deposition and anti-reflective properties of porous CaF2.
In terms of its chemical properties, 2-Dimethylaminoethanol has a clear colorless liquid appearance with a fishlike odor.
2-Dimethylaminoethanol has a flash point of 105°F and is less dense than water, with vapors heavier than air.
Combustion of 2-Dimethylaminoethanol produces toxic oxides of nitrogen.
2-Dimethylaminoethanol serves as a precursor in the production of various other chemicals.
2-Dimethylaminoethanol belongs to the class of organic compounds called 1,2-aminoalcohols, characterized by an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
2-Dimethylaminoethanol exists primarily as a solid and is highly soluble in water.
2-Dimethylaminoethanol is weakly acidic, essentially neutral based on its pKa value.
Within cells, 2-Dimethylaminoethanol is predominantly found in the cytoplasm.
2-Dimethylaminoethanol is worth noting that dimethylethanolamine is potentially toxic.
One of the key benefits of 2-Dimethylaminoethanol is its excellent solubility in both water and many organic solvents, which allows it to be easily incorporated into a wide range of chemical systems.
Its moderate basicity makes 2-Dimethylaminoethanol an efficient neutralizing agent without being excessively reactive, providing controlled pH adjustment in sensitive formulations.
2-Dimethylaminoethanol also exhibits relatively low bioaccumulation potential and is readily biodegradable under aerobic conditions, which can be advantageous from an environmental management perspective when handled properly.
From a functional standpoint, 2-Dimethylaminoethanol is characterized by its hygroscopic nature, strong amine odor, and high chemical reactivity with acids and electrophilic compounds.
2-Dimethylaminoethanol demonstrates good mobility in aqueous environments and can form stable salts with acids, which is particularly useful in formulation chemistry.
Its volatility compared to heavier amines enables 2-Dimethylaminoethanol to be effective in applications requiring vapor-phase protection, such as corrosion inhibition in closed systems.
Overall, 2-Dimethylaminoethanol’s combination of chemical reactivity, solubility, and functional flexibility makes it a valuable component in industrial chemistry, especially in formulations requiring both amine and alcohol functionalities within a single molecule.
2-Dimethylaminoethanol is miscible with water, alcohol, ether, acetone and benzene.
2-Dimethylaminoethanol is incompatible with strong oxidizers and strong acids.
USES and APPLICATIONS of 2-DIMETHYLAMINOETHANOL:
In the coatings and paints industry, 2-Dimethylaminoethanol functions as a neutralizing agent for acidic components in waterborne coatings, improving stability and dispersion of resins.
2-Dimethylaminoethanol is also used in the production of resins, polymers, and polyurethane systems, where it can serve as a catalyst or intermediate, contributing to improved reaction control and product performance.
In the textile and dye sectors, 2-Dimethylaminoethanol plays a role in dye synthesis and finishing processes, enhancing dye solubility and interaction with fibers.
Additionally, 2-Dimethylaminoethanol is utilized in the manufacture of emulsifiers, surfactants, and personal care intermediates due to its ability to modify surface activity and improve formulation compatibility.
2-Dimethylaminoethanol is a highly versatile alkanolamine widely used across multiple industrial sectors due to its dual functional structure, which contains both a tertiary amine and a primary alcohol group.
This unique chemical composition enables 2-Dimethylaminoethanol to act as a reactive intermediate, a neutralizing agent, and a corrosion inhibitor in various formulations.
In industrial water treatment systems, 2-Dimethylaminoethanol is commonly applied as a corrosion inhibitor and pH adjuster, particularly in boiler and condensate systems, where its volatility allows it to protect metal surfaces effectively throughout the system.
2-Dimethylaminoethanol is used as pharmaceutical raw materials, intermediates for the manufacture of dyes, fiber treatment agents, anti-corrosion additives, etc.
2-Dimethylaminoethanol can be used as water-soluble paint base materials, synthetic resin solvents, etc.
2-Dimethylaminoethanol is used as dye intermediates, fabric dye assistants and preservatives, and also used in the pharmaceutical industry.
2-Dimethylaminoethanol is used in ion exchange resins, polyurethane catalysts, medicine (local anesthetic tetracaine hydrochloride, antihistamines, antispasmodics and antihypertensive drugs, etc.), emulsifiers, textile auxiliaries, corrosion inhibitors, anti-scaling agent, dye and paint solvent, synthetic 763 resin and its curing agent, etc.
2-Dimethylaminoethanol is also used as fuel oil additive, as an acrylic acid derivative and used as a flocculant in urban water purification plants.
In Japan, 50% of 2-Dimethylaminoethanol is used for ion exchange resins, 13.8% is used for polyurethane catalysts, and coatings account for 11.2%.
2-Dimethylaminoethanol is used as anti-inhibitors, dye intermediates, fabric dyeing aids, preservatives in the pharmaceutical industry, and resin raw materials.
Applications of 2-Dimethylaminoethanol: Coatings, Paints, Water Treatment, Chemical Intermediate, Ion exchange resins, Emulsifying agent.
2-Dimethylaminoethanol is used as corrosion inhibitor, anti-scaling agent, paint additive, coating additive and solids separation agent.
2-Dimethylaminoethanol is also used as an intermediate for active pharmaceutical ingredients and dyes.
2-Dimethylaminoethanol serves as a curing agent for polyurethanes and epoxy resins.
Further, 2-Dimethylaminoethanol is used as an additive to boiler water.
In addition to this, 2-Dimethylaminoethanol is used therapeutically as a CNS stimulant.
2-Dimethylaminoethanol is used catalyst/intermediate in: Polyurethane production, Resin and polymer synthesis, Additive in coatings, paints, and emulsifiers, Textile and dye manufacturing, Gas treatment / neutralizing agent (amine-based systems).
2-Dimethylaminoethanol is used to make other chemicals.
2-Dimethylaminoethanol has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.
2-Dimethylaminoethanol has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.
2-Dimethylaminoethanol is an organic compound with the formula (CH3)2NCH2CH2OH.
2-Dimethylaminoethanol is used in skin care products for improving skin tone and also taken orally as a nootropic.
2-Dimethylaminoethanol is used as a curing agent for polyurethanes and epoxy resins.
2-Dimethylaminoethanol is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
2-Dimethylaminoethanol is used as a flocculating agent.
Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams.
2-Dimethylaminoethanol is widely used as: Corrosion inhibitor in water treatment systems, Intermediate in pharmaceuticals.
-Industrial applications of 2-Dimethylaminoethanol:
2-Dimethylaminoethanol is used as a curing agent for polyurethanes and epoxy resins.
2-Dimethylaminoethanol is also used extensively in water treatment.
2-Dimethylaminoethanol is also used in the synthesis of dyes, textile auxiliaries, pharmaceuticals, emulsifiers, and corrosion inhibitors, paint removers, and boiler water additives.
Some of its salts have melting points below room temperature (ionic liquids), such as 2-Dimethylaminoethanol's acetate and octanoate, and are used to replace some conventional solvents.
2-Dimethylaminoethanol is widely used in pharmaceutical manufacturing.
KEY INDUSTRIAL APPLICATIONS of 2-DIMETHYLAMINOETHANOL:
2-Dimethylaminoethanol’s multifunctional properties drive its use across diverse sectors:
As a key component in corrosion inhibitors, 2-Dimethylaminoethanol neutralizes acidic contaminants and protects metal surfaces in industrial cooling systems.
2-Dimethylaminoethanol is utilized in synthesizing anticholinergic drugs and local anesthetics, while its cholinergic properties support neurological research.
In cosmetics, 2-Dimethylaminoethanol stabilizes formulations, enhances skin firmness, and acts as an antioxidant in anti-aging products.
2-Dimethylaminoethanol accelerates epoxy resin curing and improves adhesion in paints, ensuring durable finishes.
As a dye-fixing agent, 2-Dimethylaminoethanol enhances color fastness and reduces wastewater toxicity.
CHARACTERISTICS of 2-DIMETHYLAMINOETHANOL:
2-Dimethylaminoethanol is a clear, colorless liquid with amine-like odor
2-Dimethylaminoethanol is miscible in water
2-Dimethylaminoethanol is soluble in most organic solvents
BIOCHEMISTRY of 2-DIMETHYLAMINOETHANOL:
2-Dimethylaminoethanol may be a biochemical precursor of the neurotransmitter acetylcholine, but this conclusion has been controversial.
2-Dimethylaminoethanol is generally believed that the methylation of dimethylethanolamine to produce choline occurs in the brain, but this may not be the case.
2-Dimethylaminoethanol is processed into choline in the liver, but choline cannot cross the blood-brain barrier.
PROPERTIES of 2-DIMETHYLAMINOETHANOL:
*Dual functional groups → high chemical versatility
*Strong basicity → efficient neutralization agent
*Good solubility → easy formulation in aqueous systems
*Low bioaccumulation potential → environmentally manageable
*Hygroscopic liquid
*Strong amine odor
*High mobility in soil (cationic form dominates)
*Readily biodegradable under aerobic conditions
METHODS OF MANUFACTURING of 2-DIMETHYLAMINOETHANOL:
The ethylene oxide method is obtained by amination of dimethylamine and ethylene oxide through distillation, rectification and dehydration.
The chloroethanol method is saponified from chloroethanol and alkali to generate ethylene oxide, and then synthesized with dimethylamine to obtain 2-Dimethylaminoethanol.
Industrial product 2-Dimethylaminoethanol, purity ≥95%.
Raw material consumption quota: chloroethanol (32%) 5500kg/t, dimethylamine (40%) 2200kg/t.
During production, chloroethanol can also be directly added dropwise to dimethylamine, with a yield of 85%.
PHYSICAL and CHEMICAL PROPERTIES of 2-DIMETHYLAMINOETHANOL:
Chemical Name: N,N-Dimethylethanolamine
IUPAC Name: 2-(Dimethylamino)ethanol
CAS Number: 108-01-0
EC Number: 203-542-8
MDL Number: MFCD00002846
Beilstein Number: 1209235 / 04, 276
PubChem CID: 7902
ChEBI ID: CHEBI:271436
UNSPSC Code: 12352100
InChI Key: UEEJHVSXFDXPFK-UHFFFAOYSA-N
SMILES: CN(C)CCO
Physical and Chemical Properties
Molecular Formula: C₄H₁₁NO
Molecular Weight: 89.14 g/mol
Formula Weight: 89.14 g/mol
Linear Formula: HOCH₂CH₂N(CH₃)₂
Physical State: Liquid
Appearance: Clear, colorless to pale yellow liquid
Odor: Ammoniacal, fishy
Color: Colorless to yellow
Specific Gravity: 0.888
Density: 0.89 g/cm³ at 20°C (also reported: 0.886 g/cm³)
Refractive Index (nD): 1.4290–1.4300
Surface Tension: 28.2 mN/m at 20°C
Thermal Properties
Melting Point: −59°C (also reported: −70°C)
Boiling Point: 134–136°C (lit.)
Flash Point: ~40°C (Seta closed cup, DIN 51755 Part 1)
Autoignition Temperature: 230°C at 1.013 hPa (DIN 51794)
Decomposition Temperature: Not available
Solubility
Water Solubility: Miscible at 20°C
Other Solubilities: Miscible with alcohol and ether
Partition and Vapor Data
log P: −0.25
log Pow: −0.55 at 23°C (no bioaccumulation expected)
Vapor Pressure: 816 Pa at 20°C
6.12 hPa at 20°C
~3.5 mmHg at 25°C
Relative Vapor Density: 3.03 (air = 1.0)
Acidity/Basicity & pH
pKa: 9.23 at 20°C
pKb: 4.77 at 20°C
pH: 10.5–11 (100 g/L solution at 20°C), alkaline in water
Viscosity
Kinematic Viscosity: ~3.58 mm²/s at ~21.6°C
Dynamic Viscosity: ~3.8–3.85 mPa·s at 20°C
Flammability: No solid/gas data available
Flash Point: ~40°C
Upper Explosion Limit: 12.2% (V)
Lower Explosion Limit: 1.4% (V)
Explosive Properties: No data available
Oxidizing Properties: None
Purity and Packaging
Percent Purity: 99%
Infrared Spectrum: Authentic
Molecular Weight:89.14 g/mol
XLogP3-AA:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:89.084063974 Da
Monoisotopic Mass:89.084063974 Da
Topological Polar Surface Area:23.5 Ų
Heavy Atom Count:6
Formal Charge:0
Complexity:28.7
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Molecular Formula / Molecular Weight:C4H11NO = 89.14
Physical State (20 deg.C):Liquid
Storage Temperature:Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN:108-01-0
Reaxys Registry Number:1209235
PubChem Substance ID:87567293
SDBS (AIST Spectral DB):2189
Merck Index (14):2843
MDL Number: MFCD00002846
Linear Formula:(CH3)2NCH2CH2OH
CAS Number:108-01-0
Molecular Weight:89.14
UNSPSC Code:12352100
NACRES:NA.22
PubChem Substance ID:24870734
EC Number:203-542-8
Beilstein/REAXYS Number:1209235
MDL number:MFCD00002846
Assay:≥99.5%
Chemical formula:C4H11NO
Molar mass:89.138 g·mol−1
Appearance:Colourless liquid
Odor:Fishy, ammoniacal
Density:890 mg mL−1
Melting point:−59.00 °C; −74.20 °F; 214.15 K
Boiling point:134.1 °C; 273.3 °F; 407.2 K
log P:−0.25
Vapor pressure:816 Pa (at 20 °C)
Acidity (pKa):9.23 (at 20 °C)
Basicity (pKb):4.77 (at 20 °C)
Refractive index (nD):1.4294
Chemical name (IUPAC): 2-(Dimethylamino)ethanol
CAS Number: 108-01-0
EC (EINECS) Number: 203-542-8
Molecular formula: C₄H₁₁NO
Molecular weight: 89.14 g/mol
Structure type: Alkanolamine (contains both amine and alcohol functional groups)
Physical state: Liquid
Color: Colorless to pale yellow
Odor: Strong amine-like odor
Melting point: −59 °C
Boiling point: ~134 °C
Density: ~0.89 g/cm³ (20–21 °C)
Vapor pressure: ~100 mmHg at 55 °C
Viscosity: ~3.6 mPa·s (21.6 °C)
pH: 10.5–11 (basic solution)
Log Kow: −0.55 (low bioaccumulation potential)
Solubility:
Miscible with water and alcohol
Reactivity:
Reacts with acids → forms salts
Reacts with oxidizers, acid chlorides, isocyanates (hazardous)
Chemical nature: Medium-strength organic base
Flash point: ~40 °C
Autoignition temperature: ~230 °C
Physical state:liquid
Color:clear, colorless
Odor:amine-like
Melting point/freezing point:Melting point/range:-70 °C - lit.
Initial boiling point and boiling range:134 - 136 °C - lit.
Flammability (solid,gas):No data available
Upper/lower flammability or explosive limits:Upper explosion limit:12,2 %(V)
Lower explosion limit:1,4 %(V)
Flash point:40 °C - Seta closed cup - DIN 51755 Part 1
Autoignition temperature:230 °C at 1.013 hPa - DIN 51794
Decomposition temperature:No data available
pH:10,5 - 11 at 100 g/l at 20 °C
Viscosity:Viscosity,kinematic:ca.3,58 mm2/s at ca.21,6 °C
Viscosity,dynamic:3,85 mPa.s at 20 °C
Water solubility at 20 °C:soluble
Partition coefficient:n-octanol/water log Pow:-0,55 at 23 °C - Bioaccumulation is not expected.
Vapor pressure:6,12 hPa at 20 °C
Density:0,886 g/cm3 at 20 °C - lit.
Relative density:No data available
Relative vapor density:No data available
Particle characteristics:No data available
Explosive properties:No data available
Oxidizing properties:none
Other safety information:Surface tension 28,2 mN/m at 20 °C
Relative vapor density:3,03 - (Air = 1.0)
CAS:108-01-0
IUPAC Name:2-(dimethylamino)ethan-1-ol
Molecular Formula:C4H11NO
InChI Key:UEEJHVSXFDXPFK-UHFFFAOYSA-N
SMILES:CN(C)CCO
Molecular Weight (g/mol):89.14
Appearance (Color):Clear colorless to pale yellow
Form:Liquid
Assay (GC):≥99.0%
Identification (FTIR):Conforms
Water Content (Karl Fischer Titration):≤0.5%
Refractive Index:1.4285-1.4310 @ 20°C
CAS No.:108-01-0
Molecular Formula:C4H11NO
Molecular Weight:89.14
Application:Precursor for [11C]Choline / Precursor for [18F]Fluoroalkylcholine
Presentation:Packaged in amber vials or amber screw-cap vials with teflon-coated stoppers under argon atmosphere
Storage and Stability:Store the product at -20 ℃, protected from light. Short-term storage at higher temperatures does not affect product quality.
FIRST AID MEASURES of 2-DIMETHYLAMINOETHANOL:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of 2-DIMETHYLAMINOETHANOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of 2-DIMETHYLAMINOETHANOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of 2-DIMETHYLAMINOETHANOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of 2-DIMETHYLAMINOETHANOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of 2-DIMETHYLAMINOETHANOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available