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2-Ethylhexanol appears as a dark brown liquid with an aromatic odor. Insoluble in water and less dense than water. Flash point between 140 - 175°F. 2-Ethylhexanol is a versatile solvent featuring excellent reactivity as a chemical intermediate. 2-Ethylhexanol serves as a chain terminator in synthesizing condensation polymers and as an intermediate for plasticizers.
CAS NUMBER: 104-76-7
SYNONYMS:
2-Ethylhexan-1-ol; 2-Ethylhexanol; 2-ETHYL-1-HEXANOL; 1-Hexanol, 2-ethyl-; 2-Ethyl-1-hexanol; 2-Aethylhexanol; 2-Ethyl-1-hexanol; 2-Ethyl-1-hexanol; 2-ethylhexan-1-ol; 2-Ethylhexanol; 2-EH (=2-ethyl hexanol); 2-EH alcohol; 2-ethyl 2-hexan-1-ol; 2-ethyl hexanol; 2-ethyl hexyl alcohol; 2-ethylhexan-1-ol; 2-Ethylhexanol; alcohol C8; EXXAL 8; isooctanol (=2-ethyl-1-hexanol); octyl alcohol(2-EH)(=2-ethyl-1-hexanol); 2-Etil Hegzanol; 2ETİLHEGZANOL; 2,etilhekzanol; 2-etilhexanol
2-Ethylhexanol has low volatility and enhances the flow and gloss of baking enamels. 2-Ethylhexanol is also used as dispersing agent for pigment pastes.2-Ethylhexanol (abbreviated 2-EH) is a branched, eight-carbon chiral alcohol.2-Ethylhexanol is a colorless liquid that is poorly soluble in water but soluble in most organic solvents.2-Ethylhexanol is produced on a massive scale (>2,000,000,000 kg/y) for use in numerous applications such as solvents, flavors, and fragrances and especially as a precursor for production of other chemicals such as emollients and plasticizers 2-Ethylhexanol is encountered in natural plant fragrances, and the odor has been reported as "heavy, earthy, and slightly floral" for the R enantiomer and "a light, sweet floral fragrance" for the S enantiomer.
The branching in 2-Ethylhexanol inhibits its crystallization due to packing disruption; this results in a very low freezing point. Esters of 2-Ethylhexanol are similarly affected and it therefore finds application as a feedstock in the production of plasticizers and lubricants, where its presence helps reduce viscosity and lower freezing points. Almost all 2-Ethylhexanol manufactured is used as a precursor for the synthesis of the diester bis, a plasticizer. Because it is a fatty alcohol, its esters tend to have emollient properties. 2-Ethylhexanol is also commonly used as a low volatility solvent.2-Ethylhexanol is an eight-carbon branched chain oxo alcohol having a high boiling point and slow evaporation rate. 2-Ethylhexanol is a primary alcohol that is hexan-1-ol substituted by an ethyl group at position 2. 2-Ethylhexanol has a role as a volatile oil component and a plant metabolite.2-Ethylhexanol is an important organic compound that is primarily used as a plasticizer. It can be used to help manufacturers defoam varnishes, paints, and ceramics, and be used as a low volatility solvent in the production of coatings and lacquer.
2-Ethylhexanol is used as a plasticizer, defoaming agent, wetting agent, solvent (nitrocellulose, paints, lacquers, and baking finishes), and textile finishing compound; Also used in inks, rubber, paper, lubricants, photography, and dry cleaning. 2-Ethylhexanol is used in the preparation of succinate-based plasticizers for replacing phthalate plasticizers. Also used in the preparation of polymeric plasticizers.Current opinion holds that there are no safety concerns regarding BCSA under the present levels of use and exposure. The common characteristic structural elements of the alcohols with saturated branched chain are one hydroxyl group per molecule, a C4-C12 carbon chain with one or several methyl side chains. Two members of the group, 2-ethyl-1-butanol and 2-Ethylhexanol, contain an ethyl side chain. One member contains a methoxy group. Metabolism studies are lacking for this compound, however, a methoxy group is enzymatically not readily cleaved and if it were so, another primary alcohol group would be formed.The standard air monitoring method for 2-Ethylhexanol is based on sorbent tube sampling. A reference air monitoring method for 2-Ethylhexanol was developed tested and reported by OSHA.
2-Ethylhexanol can also be used as a cetane number booster when reacted with nitric acid. It also used to react with epichlorohydrin and sodium hydroxide to produce the glycidyl ether of the molecule which is used as an epoxy reactive diluent in various coatings, adhesives and sealants applications. 2-Ethylhexanol is produced industrially by the aldol condensation of n-butyraldehyde, followed by hydrogenation of the resulting hydroxyaldehyde. About 2,500,000 tons are prepared in this way annually. The n-butyraldeheyde is made by hydroformylation of propylene, either in a self-contained plant or as the first step in a fully integrated facility. Most facilities make n-butanol and isobutanol in addition to 2-Ethylhexanol. Alcohols prepared in this way are sometimes referred to as oxo alcohols.
The overall process is very similar to that of the Guerbet reaction, by which it may also be produced.2-Ethylhexanol exhibits low toxicity in animal models, with LD50 ranging from 2-3 g/kg (rat).Although isooctanol (and the derived isooctyl prefix) is commonly used in industry to refer to 2-Ethylhexanol and its derivatives, IUPAC naming conventions dictate that this name is properly applied to another isomer of octanol, 6-methylheptan-1-ol. 2-Ethylhexanol is a primary alcohol that is hexan-1-ol substituted by an ethyl group at position 2. It has a role as a volatile oil component and a plant metabolite. 2-Ethylhexanol is found in alcoholic beverages2-Ethylhexanol occurs in corn, olive oil, tobacco, tea, rice, tamarind, grapes, blueberries etc. 2-Ethylhexanol is an eight-carbon branched chain oxo alcohol having a high boiling point and slow evaporation rate. It is a versatile solvent featuring excellent reactivity as a chemical intermediate. It serves as a chain terminator in synthesizing condensation polymers and as an intermediate for plasticizers.
2-Ethylhexanol has low volatility and enhances the flow and gloss of baking enamels. It is also used as dispersing agent for pigment pastes. 2-Ethyl-1-hexanol is suitable for use in a study to compare its susceptibilities of dynamic heat capacity and dielectric polarization under isothermal conditions. 2-Ethylhexanol may be used to study lipase-catalyzed transesterification (alcoholysis) of rapeseed oil and 2-Ethylhexanol in the absence of solvent. 2-Ethylhexanol may be used in broadband dielectric spectroscopy studies of the polyalcohols- glycerol, xylitol and sorbitol. 2-Ethylhexanol may be used in the preparation of porous beads. 2-Ethylhexanol is a colorless liquid that is poorly soluble in water but soluble in most organic solvents. It is produced on a massive scale for use in numerous applications such as solvents, flavors, and fragrances and especially as a precursor for production of other chemicals such as emollients and plasticizers. Solvent used below 10% in organic coating formulations when a late evaporating polar tail solvent is required. Also called isooctanol or isooctyl alcohol.Reported found 2-Ethylhexanol in papaya, peach, pear, blackberry, strawberry, cabbage, Parmesan and mozzarella cheese, butter, roasted chicken, cognac, sherry, grape wines, tea, avocado, kiwifruit, crab and clam.
2-Ethylhexanol is the most important C8 alcohol and is used mainly in manufacturing plasticizers. Other minor uses include the manufacturing of 2-ethylhexyl acrylate, as a dispersing agent and wetting agent, as a solvent for gums and resins, as a cosolvent for nitrocellulose, and in ceramics, paper coatings, rubber latex, textiles, and fragrances.2-Ethylhexanol is a dark brown liquid with an aromatic odor. Insoluble in water and less dense than water. Flash point between 140 - 175°F. Freezing point: -76 °C . Standard heat of formation = -103.46 kcal/mol at 25 °C. Storage conditions: Keep container tightly closed. Stored in a well-ventilated area. Keep cold. Separated from strong oxidants and strong bases. Store in an area without drain or sewer access. Ventilation along the floor.2-Ethylhexanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
2-Ethylhexanol is incompatible with strong oxidizing agents and strong acids. High-boiling point, low-volatility solvent for fats, waxes, dyes and insecticides. Starting material for the manufacture of plasticizers, lubricants and other chemical products such as raw materials for paints and coatings.Reactivity with Water No reaction.Stability During Stable; Neutralizing Agents for Acids and Caustics: Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.2-Ethylhexanol is a clear, mobile and neutral liquid with a characteristic odour. It is miscible with most common organic solvents but its miscibility with water is very limited. 2-Ethylhexanol enters into the reactions that are typical of primary alcohols. For instance, it readily forms esters with various acids.
2-Ethylhexanol is not widely used as a solvent. Its main application is as a feedstock in the manufacture of low-volatility esters, the most important of which is di-(2-ethylhexyl) phthalate, which is an all-purpose plasticizer for PVC and vinyl chloride copolymers.
Main use of 2-ethyl hexanol is that of an intermediate under strictly controlled conditions. Apart from this it is used in various products and processes as functional fluid, process chemical, cleaning agent and other purposes.2-Ethylhexanol is used to make plasticizers for polyvinyl chloride. Reaction with phthalic anhydride gives bis(2-ethyl hexyl) phthalate (DOP, DEHP). Reaction with adipic acid gives bis(2-ethyl hexyl) adipate. Moreover, esterification with acrylic acid gives 2-ethyl hexyl acrylate for use in adhesives and paints. On the other hand,because 2-Ethylhexanol can dissolve many organic materials well, 2-Ethylhexanol is widely used as a low-volatility solvent.
IUPAC NAME:
2-Ethylhexanol; 2-Ethylhexanol, ethoxylated; 2-Ethylhexyl alcohol; Ethyl hexyl alcohol; Ethylhexanol; ETHYLHEXANOL-2; Isooctyl alcohol, Isooctanol, 2-Ethyl-1-; Octanol
TRADE NAME:
1-Ethyl-1-hexanol; 1-Hexanol, 2-ethyl- (8CI, 9CI); 2-EH; 2-Ethyl-1-hexanol; 2-Ethyl-hexanol-1; 2-Ethylhexan-1-ol; 2-Ethylhexanol; 2-Ethylhexanol iso-Octanol; 2-Ethylhexanol-1; 2-Ethylhexanol; 2-Ethylhexylalcohol; Isooctanol; Octylalcohol; 2-EH; 2-Ethylhexanol; Ethylhexano; 2-Ethylhexyl alcohol; 2-Ethylhexylalkohol; 2-Etil esanolo; 2-Ethylhexanol (2-EH); Ethylhexanol; Ethylhexyl alcohol; Hexanol, 2-ethyl-; Isooctanol; Octanol; Octyl alcohol; alcol 2-etilesilic; isoottanolo; Octyl alcohol
OTHER NAME:
104-76-7; 111675-57-1
The features of this plasticizer are its low volatility, excellent gelling power, its great resistance to high and low temperatures and to water, and its outstanding dielectric properties. Other plasticizers that can be used to obtain specific properties are the corresponding esters of 2-Ethylhexanol and adipic acid para hydroxybenzoic acid ,sebacic acid, azelaic acid, trimellitic acid, stearic acid, terephthalic acid, phosporic acid. Additionally, phthalate plasticizers can be obtained from mixtures of 2-Ethylhexanol and other alcohols.Low-volatility solvent. For examples, resins, waxes, animal fats, vegetable oils and petroleum derivatives. Low-volatility ingredient in solvent blends for the dyestuffs and coatings industry. Flow and gloss improver in baking finishes.
Feedstock for the manufacture of ethoxylates (products of reaction between 2-Ethylhexanol and ethylene oxide). Feedstock in the manufacture of herbicides. Feedstock in the manufacture of extractants . In the production of the corresponding diester of maleic acid for use as a starting material for surfactants. Feedstock in the manufacture 2-Ethylhexanol sulphate which is used as a surfactant for electrolytes. In the production of 2-Ethylhexanol esters of trialkyl phosphites which can serve as a thermal stabilizer and antioxidant in plastics. In the manufacture of particularly pure grades of DOP which act as polychlorinated biphenyl substitutes in heavy-duty capacitors. In antifoams for almost all aqueous systems.
2-Ethylhexanol is a combustible and flammable liquid. In contact with strong oxidizers may cause fire. Unsuitable extinguishing media: Do not use a solid stream of water (water jet), since the stream will scatter and spread the fire. Use water spray to isolate the hazard area and to keep fire-exposed tanks cool.2-Ethylhexanol is a combustible and flammable liquid. In contact with strong oxidizers may cause fire. Vapor/air mixtures are explosive above 750C. Vapor may flow along surface to distant ignition sources and flash back. Carbon monoxide and dioxide may form when heated to decomposition. In case of large fire and remove the containers if this it is possible. Hazardous combustion products: Carbon monoxide and carbon dioxide.
Fire-fighters should wear appropriate protective equipment and selfcontained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. Clothing for firefighters (including helmets, protective boots and gloves) conforming to European standard EN 469 will provide a basic level of protection for chemical incidents.Environmental precautions: Prevent from contamination the ground and the surface water by isolating the hazard area. Contain and recover liquid when possible. Keep closed containers and dispose according to all applicable federal, state or local environment regulations .
Absorb spills with dry sand, earth or similar non-combustible absorbent material then collect into drums for later disposal. For large spills, dike and pump into suitable containers for disposal. Use water spray to reduce vapors and flush area with water. Resulted waste water will be treated in biological treatment plant. Dispose of under valid legal waste regulations. Do not use combustible materials, such as saw dust to absorb the spills. Do not flush to sewer. Use only non sparkling tools and equipment.Protective measures: Protect containers from physical damage. Use non sparkling tools, electric equipment and venting system. Sources of ignition such as smoking and open flames are prohibited when 2-Ethylhexanol is handled. Bounding and grounding are important to prevent the accumulation of static electricity and provide for its safe discharge. Bounding and grounding are required for all equipment. Do not use compressed air or oxygen for filling, discharging or handling. The personel which handling the product must wear protective equipment.
Store in a tightly closed containers in a cool, dry, well ventilated area away from sources of heat and incompatible substances. Drums must be equipped with self-closing valves, nitrogen blanket. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid). Incompatible materials: Strong oxidizers and acids. Incompatible materials for storage: Tanks constructed from normal steel are reliable for storing 2- ethylhexanol. If severe demands are imposed on the quality of the product, the tanks should be constructed of stainless steel.2-Ethylhexanol will slowly evaporate from the water surface into the atmosphere. 2-Ethylhexanol is readily biodegradable in water.The log Pow of 2.9 for 2-Ethylhexanol indicates a low potential for bioaccumulation. Low values for Koc calculated with a QSAR tool also point to low absorption to soil. In addition the substance is readily biodegradable.
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.2-Ethyl Hexanol is used for in numerous application such as fragrances, flavours and solvents. Most commonly it is used in the production of other chemicals. 2-Ethyl hexanol is an 8-carbon higher alcohol species. It is used to make the vinyl chloride plasticizer, bis(2-ethyl hexyl) phthalate. It is also used to make 2-ethyl hexyl acrylate for adhesives and paints. 2-Ethyl hexanol has very low-level impurities and may be used as a raw material for a wide variety of chemicals.Industrial uses of 2-Ethylhexanol: Distribution and formulation of the substance. Use in coatings. Examples, paints, inks, adhesives. Use in functional fluids e.g. cable oils, transfer oils, coolants, insulators, refrigerants, hydraulic fluids. Use in oil and gas field drilling. Use in laboratories including pilot plants.Use 2-Ethylhexanol in coatings (paints, inks, adhesives). Use 2-Ethylhexanol in functional fluids, cable oils, transfer oils, coolants, insulators, refrigerants, hydraulic fluids. Use in oil and gas field drilling. Use in dilutions of a concentrate to prepare various end use mixtures at dedicated and non-dedicated facilities. Use as a component of cleaning products.
The generation of waste should be avoided or minimized wherever possible. Disposal of this product, solutions and any by-products should comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with the requirements of all authorities with jurisdiction.Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and 2-Ethylhexanol is container must be disposed of in a safe way. Care should be taken when handling empty containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues. Vapor from product residues may create a highly flammable or explosive atmosphere inside the 2-Ethylhexanol container. Do not cut, weld or grind used containers unless they have been cleaned thoroughly internally.
Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers 2-Ethylhexanol is produced in the plant of Oxochimie in Lavera (France) by hydrogenation of 2-Ethylhexanol, that is obtained by aldocrotonisation of n-butyraldehyde, itself obtained by “oxo” reaction on propylene (hydroformylation). The main uses of 2-Ethylhexanol are solvent and intermediate for the manufacture of other chemicals.2-Ethylhexanol recycle distillation. Take it to an authorized incinerator for energy recovery solvents.Obtain the approval of pollution control authorities before discharging to wastewater treatment.In the production of: low-volatility esters which are then used as plasticisers in plastics; additives which improve thermal stability and oxidation resistance of plastics; surface active agents; anti-foaming agents for the textile and paper-making industries; solvents for extraction processes; brake fluids; fuel improvers (2-ethylhexyl nitrate); 2-Ethylhexanol acrylate; ethoxylated mixes (ethylene oxide derivatives); auxiliaries for agriculture; components for fire-retardant formulations (brominated derivatives); cosmetics; and pharmaceuticals.
Low-volatility solvent for vegetable oils, animal fats, resins; waxes and petrochemical products; component of low-volatility solvent systems which are used in the dye industry and/or in the paint and lacquer industry; additive which improves plastic formability and gloss of thermosetting plastics and hot-laid linings; dispersing and wetting agent in colour pastes.2-Ethylhexanol is available in bulk shipments, in steel rail tank cars, in tank-containers, in road tankers or flexitanks. Other types of containers are also allowable, if they protect the product sufficiently to maintain its quality, and if they provide safety in transport, storage, handling and use. In that case,submit the valid certificate which permits the use of that type of containers in storage and transport, or his own statement in writing on the subject. Place marking on the containers, in accordance with applicable regulations. 2-Ethylhexanol may not be transported together with strong oxidisers and acids.
Local exhaust ventilation systems and general ventilation systems in rooms to remove vapors from emission locations. Protection against accumulation of static electricity. Ignition of organic vapours may be initiated by any static discharge. Sprinkler systems, to cool down tanks/containers with water spray in case of fire. Liquid-impervious floors which make it possible to collect the spilled material and prevent its entry to the sewage system. Ex-proof wiring, lighting and ventilation systems. The storage rooms should be cool and dry.Storage for 2-Ethylhexanol conditions Keep away from ignition sources. Keep container tightly closed, in cool (0 to 49°C; 32 to 120°F) and well ventilated places. Handle and open containers with care. Containers and tanks must be properly marked. Containers and tanks must be made of the materials which are resistant to the product attack.
2-Ethylhexanol is transported in rail tankers, in road tankers, in tank-containers and/or flexitanks. The rail tankers, road tankers and tank-containers must be checked for cleanness before loading by a person who permits them to be loaded. They need to have washing/ cleaning certificates and their approval documents need to be valid.The main uses for 2-Ethylhexanol are in the production of plasticizers, coatings, adhesives and other specialty chemicals. 2-Ethylhexanol is used in the formulation of substances and mixtures such as cleaning agents, in oil field drilling and production operations, and as a flavoring additive in some foods.Environmental exposure to 2-Ethylhexanol is possible via the manufacturing process of this substance or when the substance is used in formulation under industrial settings – for example, while formulating into mixtures for inks, lubricant additives, lubricants or greases. In professional settings its use as a non-reactive processing aid also presents the potential for environmental exposure.
2-Ethylhexanol in case of skin contact Immediately wash skin with plenty of water and wash skin with soapy water for at least 5-10 minutes. Use lukewarm water if possible. Remove contaminated clothing and shoes. Rash If not, seek medical attention.Use 2-Ethylhexanol if possible, only in closed system. Avoid breathing vapors or mists. Contact with skin, eyes, or clothing Avoid it. Use personal protection as recommended in Section 8. Make sure that the work area is well ventilated. From heat, sparks, flames, and other sources of ignition (e.g. beacons, electric motors, and static electricity) keep away.2-Ethylhexanol is a clear, colourless liquid with an odour described as sweet, floral, intense, and unpleasant.2-Ethylhexanol occurs naturally in food and is also added as flavouring to foods. This compound is formulated by petrochemical synthesis and used predominately in the production of plasticizers for PVC resins, hexyl esters, and arylates. 2-Ethylhexanol is also used in textiles and as a solvent and wetting agent.
In the atmosphere, 2-Ethylhexanol occurs in the vapour phase and will undergo atmospheric degradation via photochemically produced hydroxyl radicals. It is only moderately soluble in water, from which it will volatilize or undergo biodegradation. This compound is unlikely to adsorb to sediments or soil. Plants, including a variety of fruits, are a natural source of 2-Ethylhexanol emissions. Anthropogenic emission sources of 2-Ethylhexanol include those resulting from its manufacturing and use as a solvent.2-Ethylhexanol is also released in the manufacturing of plasticizers, plastics, coatings, cetane improvers, lubricant additives, and surfactants. 2-Ethylhexanol is formed from combustion of PVC plastics and disinfection of water and wastewater using chlorine dioxide. In indoor environments, 2-Ethylhexanol is emitted from some carpeting.
2- Ethylhexanol is currently not a reportable substance for Environment Canada’s National Pollutant Release Inventory. In humans and animals, toxicity endpoints associated with acute 2-Ethylhexanol inhalation include irritation of eyes and throat, headaches, cough, dizziness, and fatigue. There is limited evidence to suggest acute, reversible neurotoxicity. No chronic effects were reported in either animal or human studies. Animal studies have concluded that 2-Ethylhexanol is neither genotoxic nor carcinogenic. No data was identified for the effects of 2-Ethylhexanol on terrestrial vegetation. In algae (Chlorella emersonii), 50 and 100 mg dm3 2-Ethylhexanol added to growth medium severely inhibited algal growth rate. The standard method for monitoring 2-Ethylhexanol in air employs the use of charcoal solid sorbent tubes. Reference air monitoring methods were limited to one method developed, tested and reported by the Occupational Safety and Health Administration (OSHA). Ambient air quality guidelines or objectives were developed for 2-Ethylhexanol by only 5 of the 22 agencies evaluated. These agencies included: Ontario, Texas, Oklahoma, Michigan, and Vermont. Where reported, the basis for the guideline or objective was odour. No guidelines were developed based on occupational exposure criteria as there were no occupational criteria for 2-Ethylhexanol.
The physical and chemical properties identified for 2-Ethylhexanol include chemical structure, molecular weight, melting and boiling points, water solubility, density, vapor density, organic carbon partition coefficient, octanol water partition coefficient, vapor pressure, Henry's Law constant, bioconcentration factor, and odour threshold. A discussion of the behaviour of 2- ethylhexanol in the environment was also presented. Existing and potential natural and anthropogenic sources of 2-Ethylhexanol emissions in Alberta were examined. The chemical is currently not a reportable substance on Environment Canada’s National Pollutant Release Inventory.Scientific information about the effects of 2-Ethylhexanol on humans, animals, and vegetation were identified. Limited data on effects in animals and humans was available from toxicity and epidemiology studies cited in peer reviewed evaluations by the World Health Organization and listed on Toxline and Medline databases. Information on the effects of 2-Ethylhexanol on vegetation were limited to one study.
Wear boots, gloves, lab coat, apron or appropriately to avoid skin contact with 2-Ethylhexanol. Wear waterproof protective clothing, including overalls. 2-Ethylhexanol overexposure headache, muscle weakness, nausea, dizziness, ataxia and may cause nervous system depression. Skin irritation may be present after prolonged or repeated exposure to 2-Ethylhexanol; this can result in some type of contact dermatitis (non-allergic). Dermatitis is usually characterized by progressive skin redness (erythema) and swelling (edema). swelling (vesiculation), scaling and thickening of the epidermis. It can be intercellular at the microscopic level edema of the spongy layer of the skin (spongiosis) and intracellular edema of the epidermis.
2-Ethylhexanol although recovery following overexposure is generally complete, cerebral micro-haemorrhage of focal post-inflammatory scarring may produce epileptiform seizures some months after the exposure. Pulmonary episodes may include chemical pneumonitis with oedema and haemorrhage.2-Ethylhexanol is readily biodegradable and has low potential for bioaccumulation. It has high solubility in water and, if accidentally released to soil or water, moderate volatilization to the atmosphere can be anticipated. 2-Ethylhexanol is not expected to adsorb to suspended solids and sediment. Volatilization from moist soil surfaces is expected to be an important fate process.Under the Globally Harmonized System for classification and labeling (GHS), substances are classified according to their physical, health, and environmental hazards. The hazards are communicated via specific labels and the SDS. GHS attempts to standardize hazard communication so that the intended audience (workers, consumers, transport workers, and can better understand the hazards of the chemicals in use.2-Ethylhexanol is used as a chemical intermediate and will not result in consumer exposures. Consumer exposure will be limited to low levels present within household product formulations such as washing and cleaning products. When handled responsibly, the potential for toxicity can be minimized, allowing consumers and workers to use materials containing 2-Ethylhexanol safely.
2-Ethylhexanol is a colorless liquid. It is a branched eight-carbon oxo alcohol that has excellent reactivity as a chemical intermediate. 2-Ethylhexanol is a low to moderate hazard material and the risk of adverse health effects associated with both occupational and consumer use of this chemical is anticipated to be low.In industrial settings, 2-Ethylhexanol is manufactured and handled in closed processes as much as possible, which ensures that worker exposure to 2-Ethylhexanol is minimized. The proper use of personal protective equipment during loading, unloading, sampling or during maintenance operations will further minimize potential exposures to 2-Ethylhexanol.2-Ethylhexanol is an important organic compound that is primarily used as a plasticizer. It can be used to help manufacturers defoam varnishes, paints, and ceramics, and be used as a low volatility solvent in the production of coatings and lacquers.Industrial: Production of substances. Formulation and (repackaging) of substances and mixtures. Distribution and storage. Usage in coatings, functional fluids, Cleaning agents and in oil and gas field drilling. As an intermediate product not related to Controlled Conditions use of the substance.
