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2-PHENYLETHANOL

2-Phenylethanol is an aromatic alcohol used as a fragrance and antimicrobial preservative in cosmetic formulations, with a characteristic rose-like odor.
2-Phenylethanol occurs naturally in essential oils like rose, carnation, and geranium, and is widely used in the perfume and flavor industries.
2-Phenylethanol has antimicrobial properties, making it a valuable preservative for cosmetics and personal care products.

CAS Number: 60-12-8
EC Number: 200-456-2
Molecular Formula: C8H10O
Molecular Weight: 122.16

Synonyms: 2-PHENYLETHANOL, Phenethyl alcohol, Phenylethyl alcohol, 60-12-8, Benzeneethanol, Phenylethanol, Benzyl carbinol, Phenethanol, 2-Phenylethyl alcohol, 2-PHENYL-ETHANOL, beta-Phenylethanol, 2-Phenethyl alcohol, Benzylmethanol, 2-Phenylethan-1-Ol, Benzylcarbinol, Methanol, benzyl-, 2-Hydroxyethylbenzene, 1-Phenyl-2-ethanol, Ethanol, 2-phenyl-, FEMA No. 2858, 2-PEA, Benzenethanol, Phenethylalcohol, Phenyl ethyl alcohol, beta-PEA, beta-Phenylethyl alcohol, beta-Hydroxyethylbenzene, Caswell No. 655C, beta-Fenylethanol, FEMA Number 2858, 1321-27-3, beta-Fenethylalkohol, Phenethyl alcohol (natural), beta-Phenethyl alcohol, HSDB 5002, 2-Phenethanol, .beta.-Hydroxyethylbenzene, .beta.-Phenylethyl alcohol, Hydroxyethylbenzene, EINECS 200-456-2, UNII-ML9LGA7468, MFCD00002886, PhenethylAlcohol-d5, EPA Pesticide Chemical Code 001503, NSC 406252, NSC-406252, BRN 1905732, .beta.-Phenylethanol, ML9LGA7468, .beta.-PEA, DTXSID9026342, CHEBI:49000, AI3-00744, (2-Hydroxyethyl)benzene, .beta.-Phenethyl alcohol, Phenylethyl alcohol [USP], .beta.-(hydroxyethyl)benzene, DTXCID206342, EC 200-456-2, 4-06-00-03067 (Beilstein Handbook Reference), NSC406252, NCGC00166215-02, Phenylethyl alcohol (USP), Ethanol, phenyl-, PHENYLETHYL ALCOHOL (II), PHENYLETHYL ALCOHOL [II], PHENETHYL ALCOHOL (MART.), PHENETHYL ALCOHOL [MART.], Phenyl Ethanol(Natural), 2 Phenylethanol, PHENYLETHYL ALCOHOL (USP-RS), PHENYLETHYL ALCOHOL [USP-RS], beta-Fenylethanol [Czech], 2-phenyl ethanol, Carbinol, Benzyl, beta Phenylethanol, CAS-60-12-8, Alcohol, Phenethyl, beta-Fenethylalkohol [Czech], PEL, SMR000059156, PHENYLETHYL ALCOHOL (USP MONOGRAPH), PHENYLETHYL ALCOHOL [USP MONOGRAPH], Alcohol, Phenylethyl, benzene-ethanol, Mellol, phenyl-ethanol, Benzyl-Methanol, 2-PhenyIethanol, phenylethyl-alcohol, .beta.-Phenethanol, HY1, .beta.-Fenylethanol, b-Hydroxyethylbenzene, Benzyl ethyl alcohol, 2-phenyl-1-ethanol, Benzeneethanol, 9CI, 2-phenylethane-1-ol, betaphenylethyl alcohol, .beta.-Fenethylalkohol, 2-Phenylethanol, USP, METHANOL, BENZYL, A-PEA, beta -hydroxyethylbenzene, 2-Phenylethanol, 99%, .beta.-P.E.A., (BETA-PEA), Phenylethyl alcohol, USAN, bmse000659, Phenylethyl, beta- alcohol, 2-(2-Hydroxyethyl)benzene, SCHEMBL1838, WLN: Q2R, MLS001066349, MLS001336026, FEMA NUMBER 2858., PHENETHYL ALCOHOL [MI], Phenethyl alcohol, 8CI, BAN, CHEMBL448500, beta-(HYDROXYETHYL)BENZENE, PHENETHYL ALCOHOL [FCC], PHENYLETHYL, B- ALCOHOL, PHENETHYL ALCOHOL [INCI], BDBM85807, FEMA 2858, HMS2093H05, HMS2233H06, HMS3374P04, Pharmakon1600-01505398, PHENYLETHYL ALCOHOL [FHFI], PHENYLETHYL ALCOHOL [HSDB], PHENETHYL ALCOHOL [WHO-DD], BCP32115, CS-B1821, HY-B1290, NSC_6054, Tox21_113544, Tox21_201322, Tox21_303383, NSC759116, s3703, 2-Phenylethanol, >=99.0% (GC), AKOS000249688, Tox21_113544_1, CCG-213419, DB02192, NSC-759116, CAS_60-12-8, Phenethyl alcohol, >=99%, FCC, FG, NCGC00166215-01, NCGC00166215-03, NCGC00166215-05, NCGC00257347-01, NCGC00258874-01, AC-18484, SBI-0206858.P001, FT-0613332, FT-0673679, P0084, EN300-19347, C05853, D00192, D70868, Phenethyl alcohol, natural, >=99%, FCC, FG, AB00698274_05, A832606, Q209463, SR-01000763553, Phenylethyl alcohol, >=99%, FCC, FG, Phenylethyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material, 19601-20-8.

2-Phenylethanol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.
The molecule of 2-Phenylethanol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).

2-Phenylethanol is an aromatic alcohol used as a flavoring agent in the cosmetic, perfume, and food industries.
2-Phenylethanol, also known as beta-phenylethyl alcohol, is a colorless liquid with a floral, rose-like scent.

2-Phenylethanol is a primary alcohol and belongs to the class of compounds known as phenols.
The chemical formula for 2-Phenylethanol is C8H10O.

2-Phenylethanol is a kind of edible spices, and naturally exists in neroli, rose oil, geranium oil and other oils, because 2-Phenylethanol has a soft, pleasant and persistent rose fragrance and is widely used in various kinds of flavors and cigarette flavor.
2-Phenylethanol is dispensing rose scent, food additives, the main raw material for rose scent flavor, stable on alkali, which are widely used in soap fragrance, is essence blending all rose scent series of spices, because 2-Phenylethanol does not dissolve in water, it is often used in the making up water, soap and orange flower, purple, etc.

2-Phenylethanol is also used in the blending of flavor.
Because the 2-Phenylethanol has a good antibacterial efficiency, 2-Phenylethanol can be used in the ophthalmic solution.

2-Phenylethanol has a characteristic rose-like odor and an initially slightly bitter taste, then sweet and reminiscent of peach.
2-Phenylethanol, an aromatic alcohol with rose-like odor, is commonly used as a food flavoring and fragrance ingredient.

2-Phenylethanol is the main flavor volatile of tomato and blue cheese.
2-Phenylethanol is a clear, colorless liquid with an odor of rose oil.

2-Phenylethanol has a burning taste that irritates and then anesthetizes mucous membranes.
2-Phenylethanol is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations.

2-Phenylethanol is active at pH 6 or less and is inactivated by nonionic detergents including polysorbate-80.
2-Phenylethanol is also a widely used fragrance material that imparts a rose character to perfume compositions.

Almost all rose fragrances and other floral-type perfumes contain 2-Phenylethanol, and 2-Phenylethanol is used extensively for many other fragrance applications because 2-Phenylethanol blends ell.
2-Phenylethanol is metabolized to phenylacetic acid in mammals.
In humans, 2-Phenylethanol is excreted in urine as the conjugate phenylacetylglutamine.

2-Phenylethanol is a clear, colorless liquid with a floral fragrance that is commonly used in cosmetics and personal care products as a preservative.
2-Phenylethanol is chemical formula is C8H10O, and 2-Phenylethanol is naturally derived from plants such as rose and jasmine.

2-Phenylethanol is effective against bacteria, fungi, and viruses, making 2-Phenylethanol a popular alternative to synthetic preservatives.
2-Phenylethanol is soluble in both oil and water, which allows 2-Phenylethanol to be easily incorporated into a wide range of cosmetic formulations.

With 2-Phenylethanol natural origin and broad-spectrum antimicrobial properties, 2-Phenylethanol is a good choice for those looking for safe and effective preservatives.
2-phenylethanol is a primary alcohol that is ethanol substituted by a phenyl group at position 2.

2-Phenylethanol has a role as a fragrance, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Aspergillus metabolite and a plant growth retardant.
2-Phenylethanol is a primary alcohol and a member of benzenes.

2-Phenylethanol, is a primary aromatic alcohol of high boiling point, having a characteristic rose-like odor.
2-Phenylethanol presents organoleptic properties and impacts the quality of the wine, distilled beverages, and fermented foods.

2-Phenylethanol shows its presence in fresh beer and is responsible for the rose-like odor of well-ripened cheese.
2-Phenylethanol is commercially and industrially an important flavor and is a component of a variety of foodstuffs such as ice cream, gelatin, candy, pudding, chewing gum, and non-alcoholic beverages.

2-Phenylethanol is formed by yeasts during fermentation of alcohols either by decomposition of L-phenylalanine or metabolism of sugar substrates.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
2-Phenylethanol is prepared commercially via two routes.

Most common is the Friedel-Crafts reaction between benzene and ethylene oxide in the presence of aluminium trichloride.
C6H6 + CH2CH2O + AlCl3 → C6H5CH2CH2OAlCl2 + HCl

The reaction affords the aluminium alkoxide that is subsequently hydrolyzed to the desired product.

The main side product is 2-Phenylethanol, which can be avoided by use of excess benzene.
2-Phenylethanol of styrene oxide also affords 2-Phenylethanol.

2-Phenylethanol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
2-Phenylethanol is also an autoantibiotic produced by the fungus Candida albicans.

2-Phenylethanol is therefore a common ingredient in flavors and perfumery, particularly when the odor of rose is desired.
2-Phenylethanol is used as an additive in cigarettes.

2-Phenylethanol is also used as a preservative in soaps due to 2-Phenylethanol stability in basic conditions.
2-Phenylethanol is of interest due to its antimicrobial properties.

2-Phenylethanol a colorless liquid used in small amounts as a so-called masking ingredient, meaning 2-Phenylethanol can hide the natural not-so-nice smell of other cosmetic ingredients.
2-Phenylethanol has a nice rose-like scent and can be found in several essential oils such as rose, neroli or geranium.

2-Phenylethanol also has some antimicrobial activity and can boost the performance of traditional preservatives.
2-Phenylethanol is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations.

2-Phenylethanol is an aromatic chemical, usually appearing as a clear oily liquid with a sweet rose scent.

2-Phenylethanol can be synthesized for industry through the use of yeast strains or by reacting benzene and ethylene oxide with a catalyst.
2-Phenylethanol is naturally present in grapes and wines, and is also found in the essential oils of many plants such as ylang ylang, hyacinth and carnation.

2-Phenylethanol is the dominant odour in fresh roses such as Rosa multiflora, however is mostly lost during essential oil production as 2-Phenylethanol separates, with only a fraction remaining in rose oil.
2-Phenylethanols are a large class of important cosmetic ingredients but only ethanol needs to be denatured to prevent 2-Phenylethanol from being redirected from cosmetic applications to alcoholic beverages.

2-Phenylethanol is a colorless, transparent, slightly viscous liquid.
In cosmetics and personal care products, 2-Phenylethanol is used in the formulation of eye area makeup, makeup products, skin care products, shampoos and perfumes and colognes.

2-Phenylethanol is a primary alcohol that is ethanol substituted by a phenyl group at position 2.
2-Phenylethanol has a role as a fragrance, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Aspergillus metabolite and a plant growth retardant.

2-Phenylethanol is a primary alcohol and a member of benzenes.
2-Phenylethanol is a water soluble fragrance agent with rose like scent and good antimicrobial activity.

Perfect suitable for water based products and colour cosmetics.
The combination with boosting agents is in emulsions recommendable, the performance is pH independent.

2-Phenylethanol is an organic compound with the chemical formula C6H5CH2CH2OH.
2-Phenylethanol is a colourless liquid with a pleasant floral odor.

2-Phenylethanol occurs widely in nature, being found in a variety of essential oils.
2-Phenylethanol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.

The molecule of 2-Phenylethanol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).
2-Phenylethanol, extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water.

2-Phenylethanol has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans.
2-Phenylethanol is used as an additive in cigarettes and also used as a preservative in soaps due to 2-Phenylethanol stability in basic conditions.
2-Phenylethanol, extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid.

2-Phenylethanol occurs naturally in some essential oils, such as rose oil, carnation oil, and geranium oil, contributing to their pleasant fragrance.
2-Phenylethanol is commonly used in the perfume and flavor industries due to 2-Phenylethanol floral aroma.

Additionally, 2-Phenylethanol has antimicrobial properties, which makes 2-Phenylethanol useful in various cosmetic and personal care products as a preservative.
2-Phenylethanol occurs naturally in various plants, including roses, carnations, geraniums, and other flowers.

2-Phenylethanol is extracted from these sources for use in the fragrance industry.
One of the primary uses of 2-Phenylethanol is in the fragrance and perfume industry.
2-Phenylethanol is pleasant, floral scent, reminiscent of roses, makes 2-Phenylethanol a popular choice for adding a sweet and rosy note to perfumes and cosmetic products.

In addition to its use in perfumery, 2-Phenylethanol is sometimes used as a flavoring agent in the food industry, providing a sweet and floral taste to certain products.
2-Phenylethanol has antimicrobial properties, and as such, 2-Phenylethanol is employed as a preservative in various cosmetic and personal care products.

2-Phenylethanol helps extend the shelf life of these products by inhibiting the growth of bacteria and fungi.
2-Phenylethanol can be synthesized chemically through various methods, including the reduction of phenylacetic acid or the hydration of styrene.

Synthetic 2-Phenylethanol is often used in the fragrance industry when a cost-effective and consistent source is needed.
2-Phenylethanol can act as a solvent for various substances, which adds to 2-Phenylethanol versatility in different industrial applications.

2-Phenylethanol is generally considered safe for use in cosmetics and personal care products when used in accordance with regulations.
However, like any chemical, 2-Phenylethanol should be handled with care, and 2-Phenylethanol concentration in formulations should comply with safety guidelines.

2-Phenylethanol is the main component of rose oils obtained from rose blossoms.
2-Phenylethanol occurs in smaller quantities in neroli oil, ylang-ylang oil, carnation oil, and geranium oils.
Since the alcohol is rather soluble in water, losses occur when essential oils are produced by steam distillation.

2-Phenylethanol is a colorless liquid with a mild rose odor.
2-Phenylethanol can be dehydrogenated catalytically to phenylacetaldehyde and oxidized to phenylacetic acid (e.g.,with chromic acid).

2-Phenylethanol is fatty acid esterswith lowermolecularmass, as well as some alkyl ethers, are valuable fragrance and flavor substances.
Phenylethyl Alcohol is found in almond.

2-Phenylethanol is a component of ylang-ylang oil.
2-Phenylethanol is a flavouring ingredient.

2-Phenylethanol is also called P-2-Phenylethanol, p-phenyl ethyl alcohol, 2-phenyl ethanol, Phenethyl alcohol, benzyl carbinol, and p-hydroxyethylben.
2-Phenylethanol is a colorless, transparent, slightly viscous liquid with a sharp, burning taste.

2-Phenylethanol has a floral odor with a rose.
The molecular weight of 2-Phenylethanol is 122.1 7.

2-Phenylethanol has a specific gravity of 1.0202 at 20°C (compared with water at 4°C) and a specific gravity of 1.01 7 to 1.01 9 at 25°C (compared with water at 25°C).
The boiling point of 2-Phenylethanol at 750 mm Hg is 219 to 221"C, at 14 mm Hg is 104"C, at 12 mm Hg is 98 to 1 OO"C, and at 10 mm Hg is 97.4"C.

The freezing point of 2-Phenylethanol is -27°C.
The alcohol is combustible, and 2-Phenylethanol flash point is 102.2"C.

The index of refraction for 2-Phenylethanol at 20°C for sodium light is 1.530 to 1.534.(2~4-6)
2-Phenylethanol is very soluble in alcohol and ether.

2-Phenylethanol is also soluble in fixed oils, glycerol, and propylene glycol and is slightly soluble in mineral oil.
A 2-ml sample of 2-Phenylethanol will dissolve in 100 ml of water after thorough Exposure to air may cause a slight oxidation of 2-Phenylethanol.
2-Phenylethanol can be oxidized by acids and other oxidants, and oxidation in the presence of air is accelerated by heat.

2-Phenylethanol is stable in colorless glass ampules at room temperature or in full opaque containers stored at 4 to 27°C for up to 1 year.
2-Phenylethanol is absorbed by polyethylene c~ntainers.

2-Phenylethanol occurs naturally in the environment.
2-Phenylethanol is produced by microorganisms, plants, and animals.

2-Phenylethanol has been found as the free alcohol oresterified in a number of natural essential oils, and in food, spices, and tobacco.
2-Phenylethanol is used as a preservative ingredient in some soaps, and is also used in cosmetics, personal care products and food production for creating floral-rose fragrances and flavours.

2-Phenylethanol can be produced through various methods, including chemical synthesis and natural extraction from plants such as rose and jasmine.
The most common method involves the reduction of benzaldehyde with sodium borohydride in the presence of a catalyst.

The resulting product is then purified to obtain 2-Phenylethanol.
2-Phenylethanol is a 2-Phenylethanol that prevents or retards bacterial growth, and thus protects cosmetics and personal care products from spoilage.

2-Phenylethanol is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence.
2-Phenylethanol is a natural and multifunctional ingredient with a pleasant floral odor.

Due to 2-Phenylethanol excellent antimicrobial properties 2-Phenylethanol is used in cosmetics as a preservative booster to reduce traditional preservative use.
Contrarily to organic salt preservatives which require a low pH for optimum action, 2-Phenylethanol is pH independent.

2-Phenylethanol is efficient in a broad pH range and heat stable.
For this reason, 2-Phenylethanol can be used in all kinds of products in cosmetics and perfumery, as a deodorant active and for alternative preservation.

2-Phenylethanol is soluble in water and in most organic solvents.
2-Phenylethanol is the organic compound that consists of a phenethyl group group attached to OH.

2-Phenylethanol is a colourless liquid that is slightly soluble in water, but miscible with most organic solvents.
Incompatible with oxidizing agents and protein, e.g. serum.

2-Phenylethanol is partially inactivated by polysorbates, although this is not as great as the reduction in antimicrobial activity that occurs with parabens and polysorbates.
Purify the ethanol by shaking 2-Phenylethanol with a solution of ferrous sulfate, and the alcohol layer is washed with distilled water and fractionally distilled.

2-Phenylethanol was not mutagenic in bacterial assays, nor did 2-Phenylethanol increase the number of sister chromatid exchanges in human lymphocytes.

2-Phenylethanol can also be prepared by the reaction between phenylmagnesium bromide and ethylene oxide:
C6H5MgBr + CH2CH2O → C6H5CH2CH2OMgBr
C6H5CH2CH2OMgBr + H+ → C6H5CH2CH2OH + MgBr+

2-Phenylethanol can also be produced by biotransformation from L-phenylalanine using immobilized yeast Saccharomyces cerevisiae.
2-Phenylethanol is also possible to produce 2-Phenylethanol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF.

2-Phenylethanol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
2-Phenylethanol is also used as a preservative in soaps due to 2-Phenylethanol stability in basic conditions.

2-Phenylethanol is of interest due to its antimicrobial properties.
Besides being found in essential oils of plants, 2-Phenylethanol is a natural component of some fruits.

2-Phenylethanol contributes to the characteristic aroma of certain fruits like apples and strawberries.
There is ongoing research into the potential therapeutic properties of 2-Phenylethanol.

Some studies suggest that 2-Phenylethanol may have anti-inflammatory and antioxidant effects.
However, more research is needed to fully understand 2-Phenylethanol potential medical applications.

2-Phenylethanol is used in various industrial processes.
For example, 2-Phenylethanol can be utilized as a precursor in the synthesis of other chemicals, including pharmaceuticals and agrochemicals.

2-Phenylethanol is present in trace amounts in wine and is considered one of the volatile compounds that contribute to the overall aroma and flavor profile of the wine.
In perfumery, 2-Phenylethanol is often used in combination with other aromatic compounds to create complex and well-balanced fragrances.

2-Phenylethanol is mild and floral scent makes 2-Phenylethanol a versatile ingredient in fragrance formulations.
The use of 2-Phenylethanol is subject to regulations and guidelines set by regulatory authorities in different countries.

2-Phenylethanol is important for industries to comply with these regulations to ensure the safety and proper labeling of products containing this compound.
2-Phenylethanol is relatively stable, but like many chemicals, 2-Phenylethanol can degrade over time, especially when exposed to light and air.

Proper storage conditions, such as keeping 2-Phenylethanol in a cool and dark place, are important to maintain 2-Phenylethanol quality.
The environmental impact of 2-Phenylethanol depends on factors such as 2-Phenylethanol source (natural or synthetic) and the specific application.
In general, when used responsibly and in accordance with regulations, 2-Phenylethanol impact on the environment is considered minimal.

Uses of 2-Phenylethanol:
2-Phenylethanol is qualitatively and quantitatively one of the most important fragrance substances that belongs to the class of araliphatic alcohols.
2-Phenylethanol is used frequently and in large amounts as a fragrance material.

2-Phenylethanol is a popular component in rose-type compositions, but 2-Phenylethanol is also used in other blossom notes.
2-Phenylethanol is stable to alkali and, therefore, ideally suited for use in soap perfumes.

2-Phenylethanol is used to mask odor and also as a preservative.
2-Phenylethanol may be employed in the pharmaceutical industry as an ingredient in certain drug formulations.

2-Phenylethanol is antimicrobial properties can contribute to the stability and preservation of pharmaceutical products.
The mild and pleasant scent of 2-Phenylethanol makes it suitable for use in insect repellents.

2-Phenylethanol can be included in formulations to improve the overall fragrance of these products.
2-Phenylethanol is sometimes used in the production of scented candles and air fresheners to impart a floral fragrance, enhancing the ambiance of living spaces.

Beyond cosmetics, 2-Phenylethanol is often included in various personal care products such as shampoos, conditioners, and body lotions for 2-Phenylethanol fragrance and preservative properties.
Due to 2-Phenylethanol solvent properties, 2-Phenylethanol can be used in the textile industry for processes like dyeing and finishing fabrics.

2-Phenylethanol may be found in a range of household products, including cleaning solutions, fabric softeners, and laundry detergents, where 2-Phenylethanol antimicrobial properties contribute to product preservation.
In microbiology labs, 2-Phenylethanol is sometimes used as a disinfectant or as part of media formulations for culturing microorganisms.

2-Phenylethanol's antimicrobial properties make it a potential candidate for use in food packaging materials to inhibit the growth of microorganisms and extend the shelf life of packaged foods.
2-Phenylethanol can be found in hair care products such as shampoos, conditioners, and styling products due to 2-Phenylethanol pleasing fragrance and preservative properties.

2-Phenylethanol is sometimes used in the production of herbal extracts and tinctures, contributing to the overall aroma of the final product.
The antimicrobial properties of 2-Phenylethanol make it a suitable ingredient in liquid soaps and body washes, helping to keep the products free from harmful microorganisms.

2-Phenylethanol may be included in some mouthwashes and oral care products for 2-Phenylethanol antimicrobial effects and to enhance 2-Phenylethanol's overall scent.
Some pet grooming products, such as shampoos and conditioners, may contain 2-Phenylethanol for its fragrance and preservative qualities.

2-Phenylethanol can be found in floral waters and hydrosols, contributing to the aromatic properties of these products.
2-Phenylethanol is used in the formulation of room sprays and air fresheners to provide a pleasant and long-lasting fragrance.

In niche and artisanal perfumery, where unique and specialized fragrances are crafted, 2-Phenylethanol is valued for its floral and versatile characteristics.
In the production of botanical extracts used in skincare and cosmetic formulations, 2-Phenylethanol may be employed for its aromatic qualities.

Some agricultural products, such as certain plant-based insecticides or repellents, may utilize 2-Phenylethanol for its pleasant scent.
In the production of natural and organic cosmetic and personal care products, 2-Phenylethanol is sometimes favored for its natural origin and pleasant fragrance.

Some niche and specialty food and beverage products may incorporate 2-Phenylethanol for its unique floral and sweet aroma.
2-Phenylethanol can be found in nail polishes, nail polish removers, and other nail care products due to 2-Phenylethanol fragrance and potential antimicrobial benefits.

2-Phenylethanol is used in both aqueous and alcoholic perfume formulations, contributing to the fragrance stability in various types of perfumes.
In the formulation of biodegradable and environmentally friendly cleaners, 2-Phenylethanol may be used for its cleaning properties and mild scent.

Some lotions and moisturizers may include 2-Phenylethanol as part of their formulation for its preservative properties and fragrance.
Due to its antimicrobial properties, 2-Phenylethanol may be found in antiseptic solutions used for skin disinfection.

In certain industrial applications, 2-Phenylethanol can be used as a solvent in UV-curable coatings, contributing to the coating's formulation and properties.
2-Phenylethanol might be included in grooming sprays for pets to provide a pleasant scent and potentially help in controlling odors.

Some dental products, such as mouth rinses and dental gels, may contain 2-Phenylethanol for its potential antimicrobial effects and fragrance.
Beyond 2-Phenylethanol use as a flavoring agent in the food industry, 2-Phenylethanol is sometimes employed in the creation of floral and fruity flavorings for various food products.

In some culinary applications, 2-Phenylethanol might be used to enhance the aroma and flavor of specific dishes or desserts.
2-Phenylethanol is used as a preservative in cleansers, toners, moisturizers, and other cosmetic formulations.
2-Phenylethanol helps in extending the shelf life of products and protects against harmful microorganisms.

Additionally, the skin conditioning properties of 2-Phenylethanol make it a popular ingredient in moisturizers and other skincare products

Cosmetic products:
Apart from acting as a preservative, 2-Phenylethanol is commonly used as a fragrance ingredient, adding a floral scent to cosmetic products.
2-Phenylethanol can be found in a wide range of cosmetics, including foundations, blushes and eye shadows.

2-Phenylethanol is used in food flavors, especially in honey, bread, apple, rose flavor and so on.
2-Phenylethanol is used in tobacco flavors.

2-Phenylethanol is used for blending rose essential oil and all kinds of fragrance, such as jasmine, lilac, and orange blossom fragrance, etc.
2-Phenylethanol is used as an additive in cigarettes.

2-Phenylethanol is a common ingredient in the fragrance and perfume industry.
2-Phenylethanol is sweet, floral scent, reminiscent of roses, makes 2-Phenylethanol a popular choice for adding a rosy note to perfumes and personal care products.

In the food industry, 2-Phenylethanol is used as a flavoring agent to impart a sweet and floral taste to certain products.
2-Phenylethanol can be found in various food and beverage items.

Due to 2-Phenylethanol antimicrobial properties, 2-Phenylethanol is used as a preservative in cosmetics, skincare products, and toiletries.
2-Phenylethanol helps prevent the growth of bacteria and fungi, extending the shelf life of these products.

2-Phenylethanol serves as a solvent in industrial processes, contributing to 2-Phenylethanol versatility.
2-Phenylethanol can be used in the synthesis of various chemicals, including pharmaceuticals and agrochemicals.

While still being explored, research suggests that 2-Phenylethanol may have potential therapeutic properties.
2-Phenylethanol has been studied for its anti-inflammatory and antioxidant effects, but more research is needed to confirm these findings.

Natural 2-Phenylethanol found in some fruits contributes to the characteristic aroma and flavor of certain foods, including apples and strawberries.
2-Phenylethanol is present in trace amounts in wine and contributes to 2-Phenylethanol overall aroma and flavor profile.

2-Phenylethanol is considered one of the volatile compounds influencing the sensory characteristics of wine.
The antimicrobial properties of 2-Phenylethanol make it a suitable ingredient in some household cleaning products, detergents, and disinfectants.

2-Phenylethanol's pleasant scent makes it suitable for use in aromatherapy products, such as essential oil blends or diffuser oils.
2-Phenylethanol is used in research and development laboratories, often as a reference compound or as a starting material in chemical synthesis.

2-Phenylethanol is used as an antimicrobial preservative in nasal, ophthalmic, and otic formulations at 0.25–0.5% v/v concentration; 2-Phenylethanol is generally used in combination with other preservatives.
2-Phenylethanol has also been used on its own as an antimicrobial preservative at concentrations up to 1% v/v in topical preparations.

At this concentration, mycoplasmas are inactivated within 20 minutes, although enveloped viruses are resistant.
2-Phenylethanol is also used in flavors and as a perfumery component, especially in rose perfumes.

Production of 2-Phenylethanol:

Many syntheticmethods are known for preparing 2-Phenylethanol; the following are currently of industrial importance:

1) Friedel–Crafts reaction of benzene and ethylene oxide:

In the presence of molar quantities of aluminum chloride, ethylene oxide reacts with benzene to give an addition product, which is hydrolyzed to phenylethyl alcohol:
Friedel–Crafts reaction of benzene and ethylene oxide.
Formation of by-products, such as 1,2-diphenylethane, is largely avoided by using an excess of benzene at low temperature.
Special purification procedures are required to obtain a pure 2-Phenylethanol that is free of chlorine and suitable for use in perfumery.

2) Hydrogenation of styrene oxide:
Excellent yields of 2-Phenylethanol are obtainedwhen styrene oxide is hydrogenated at low temperature, using Raney nickel as a catalyst and a small amount of sodium hydroxide.

Storage of 2-Phenylethanol:
2-Phenylethanol is stable in bulk, but is volatile and sensitive to light and oxidizing agents.
2-Phenylethanol is reasonably stable in both acidic and alkaline solutions.

Aqueous solutions may be sterilized by autoclaving.
If stored in low-density polyethylene containers, 2-Phenylethanol may be absorbed by the containers.

Losses to polypropylene containers have been reported to be insignificant over 12 weeks at 30°C.
The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.

Safety Profile of 2-Phenylethanol:
Moderately toxic by ingestion and skin contact.
2-Phenylethanol a skin and eye irritant.

Experimental teratogenic effects.
Other experimental reproductive effects.

Causes severe central nervous system injury to experimental animals.
Combustible when exposed to heat or flame; can react with oxidzing materials.

When heated to decomposition 2-Phenylethanol emits acrid smoke and irritating fumes
2-Phenylethanol is generally regarded as a nontoxic and nonirritant material.

However, at the concentration used to preserve eye-drops (about 0.5% v/v) or above, eye irritation may occur.
2-Phenylethanol can be produced through various methods, including chemical synthesis and natural extraction from plants such as rose and jasmine.

The most common method involves the reduction of benzaldehyde with sodium borohydride in the presence of a catalyst.
The resulting 2-Phenylethanol is then purified to obtain 2-Phenylethanol.

Identifiers of 2-Phenylethanol:
CAS Number: 60-12-8
Molecular Formula: C8H10O
Molecular Weight: 122.16
EINECS Number: 200-456-2

Merck: 14,7224
JECFA Number: 987
BRN: 1905732
Stability: Stable. Substances to be avoided include strong acids and strong oxidizing agents. Combustible.
InChIKey: WRMNZCZEMHIOCP-UHFFFAOYSA-N
LogP: 1.50

Properties of 2-Phenylethanol:
Melting point: -27 °C (lit.)
Boiling point: 219-221 °C/750 mmHg (lit.)
Density: 1.020 g/mL at 20 °C (lit.)
vapor density: 4.21 (vs air)
vapor pressure: 1 mm Hg ( 58 °C)
refractive index: n20/D 1.5317(lit.)
FEMA: 2858 | 2-Phenylethanol
Flash point: 216 °F
storage temp.: Store below +30°C.
solubility: Miscible with chloroform.
form: Liquid
pka: 15.17±0.10(Predicted)
color: Clear colorless
Odor: floral odor of roses
PH: 6-7 (20g/l, H2O, 20℃)
explosive limit 1.4-11.9%(V)
Odor Type: floral
Water Solubility: 20 g/L (20 ºC)
Dielectric constant: 13.0（20℃）