PRODUCTS

2-SULFANYLETHANOL

2-Sulfanylethanol is a clear, colorless to pale yellow liquid with a strong, unpleasant thiol odor, fully miscible with water and many organic solvents, and valued for its dual hydroxyl (-OH) and thiol (-SH) functional groups that give it strong nucleophilic and reducing properties.
2-Sulfanylethanol is widely used in biotechnology, pharmaceuticals, and industrial chemistry as a potent reducing agent to cleave disulfide bonds in proteins, maintain sulfhydryl groups in a reduced state, stabilize enzymes, and act as a chain-transfer agent in polymerization processes.
Beyond research, 2-Sulfanylethanol serves in the polymer and rubber industries as a chain-transfer agent, in chemical synthesis as a nucleophile or catalyst, and in specialty applications such as corrosion inhibition, water treatment, and electronics manufacturing.

CAS Number: 60-24-2
EC Number: 200-464-6
Molecular Formula: C2H6OS
Molecular Weight: 78.13 g/mol

Synonyms: 2-mercaptoethanol, Beta-Mercaptoethanol, 60-24-2, Mercaptoethanol, 2-Sulfanylethanol, Thioglycol, Ethanol, 2-mercapto-, 2-Thioethanol, Thiomonoglycol, Thioethylene glycol, 2-Hydroxyethanethiol, 2-Hydroxyethyl mercaptan, 2-Hydroxy-1-ethanethiol, Monothioglycol, 2-Mercapto-1-ethanol, 1-Ethanol-2-thiol, Hydroxyethyl mercaptan, Monothioethylene glycol, 2-Mercaptoethyl alcohol, 2-ME, Ethylene glycol, monothio-, 1-Hydroxy-2-mercaptoethane, 1-Mercapto-2-hydroxyethane, 2-Hydroxyethylmercaptan, Emery 5791, USAF EK-4196, 2-sulfanylethan-1-ol, .beta.-Mercaptoethanol, .beta.-Hydroxyethanethiol, NSC 3723, UNII-14R9K67URN, 2-mercapto ethanol, .beta.-Hydroxyethylmercaptan, 14R9K67URN, DTXSID4026343, CHEBI:41218, 155613-89-1, Mercaptoetanol, Monothioethyleneglycol, 2-Mercaptoethanol, >=99.0%, beta-Hydroxyethanethiol, beta-Hydroxyethylmercaptan, Cuprate(6-), .mu.-2,2-(1-methyl-1,2-ethanediyl)bisimino(6-fluoro-1,3,5-triazine-4,2-diyl)imino(2-hyd, CCRIS 2097, HSDB 5199, EINECS 200-464-6, UN2966, BRN 0773648, 2mercaptoethanol, AI3-07710, b-mercaptoethanol, 2-mercapto-ethanol, 2-sulfanyl-ethanol, beta-sulfanylethanol, hydroxyethyl sulfide, mercaptoethyl alcohol, MFCD00004890, 2-Sulfanylethanol #, 2-hydroxy-ethanethiol, 2-mercaptoethan-1-ol, HSCH2CH2OH, WLN: SH2Q, EC 200-464-6, 4-01-00-02428 (Beilstein Handbook Reference), DivK1c_000784, BDBM7971, CHEMBL254951, HMS502H06, KBio1_000784, NSC3723, NINDS_000784, NSC-3723, Thioglycol [UN2966] [Poison], ZINC8216595, STL482546, 2-Mercaptoethanol, for electrophoresis, AKOS000118900, CCG-231050, DB03345, MCULE-2252943288, UN 2966, IDI1_000784, BP-21398, 2-Mercaptoethanol, for synthesis, 99.0%, DS-014379, M0058, M1948, C00928, 2-Mercaptoethanol, SAJ special grade, >=99.0%, A832651, Q411084, Q-200296, 3-Pyridinecarbonitrile, 4-methyl-2,6-di-5-morpholinyl-, F0001-1577, 2-Mercaptoethanol, for HPLC derivatization, >=99.0% (GC), 2-Mercaptoethanol, BioUltra, for molecular biology, >=99.0% (GC), 2-Mercaptoethanol, for molecular biology, for electrophoresis, suitable for cell culture, BioReagent, 99% (GC/titration), 2-Mercaptoethanol, PharmaGrade, Manufactured under appropriate controls for use as raw material in pharma or biopharmaceutical production., Cuprate(6-), [.mu.-[[2,2'-[(1-methyl-1,2-ethanediyl)bis[imino(6-fluoro-1,3,5-triazine-4,2-diyl)imino[2-(hydroxy-.kappa.O)-5-sulfo-3,1-phenylene](2,1-diazenediyl-.kappa.N2)(phenylmethylene)-2,1-diazenediyl-.kappa.N1]]bis[4-sulfobenzoato-.kappa.O]](10-)]]di-, sodium

2-Sulfanylethanol is a clear, colorless to pale yellow liquid with a strong, unpleasant odor reminiscent of rotten eggs, due to its thiol group.
2-Sulfanylethanol is a low-viscosity, polar compound that is miscible with water and many organic solvents, with a boiling point of about 157 °C and a melting point near −98 °C.

Chemically, 2-Sulfanylethanol contains both a hydroxyl (-OH) and a thiol (-SH) functional group, giving it strong nucleophilic and reducing properties.
2-Sulfanylethanol is widely used in biochemical and molecular biology laboratories as a reducing agent to break disulfide bonds in proteins, maintaining them in their reduced and denatured state during electrophoresis (e.g., SDS-PAGE) and enzyme assays.

2-Sulfanylethanol also serves as an antioxidant in cell culture media, a stabilizer in enzyme preparations, and an intermediate in the synthesis of various chemicals.
Although valuable in research and industrial applications, 2-Sulfanylethanol is toxic by inhalation, ingestion, and skin absorption, and its vapors are irritating to the eyes, skin, and respiratory tract, requiring strict handling precautions, good ventilation, and appropriate personal protective equipment.

2-Sulfanylethanol is a thiol compound, commonly used as a reducing agent in organic reactions.
2-Sulfanylethanol is the chemical compound with the formula HOCH2CH2SH.

2-Sulfanylethanol is commonly abbreviated, is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals (amongst others).
Due to 2-Sulfanylethanol's diminished vapor pressure, its odor, while unpleasant, is less objectionable than related thiols.

2-Sulfanylethanol is a potent reducing agent used in cell culture media to prevent toxic levels of oxygen radicals.
2-Sulfanylethanol is not stable in solution, so most protocols require daily supplementation.

2-Sulfanylethanol is a primary alcohol and an alkanethiol.
2-Sulfanylethanol has a role as a geroprotector.

2-Sulfanylethanol is a water-soluble thiol derived from hydrogen sulfide and ethanol.
2-Sulfanylethanol is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.

2-Sulfanylethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis (typically used in SDS-PAGE sample buffer at 5% concentration).
Also 2-Sulfanylethanol reduces excess oxidative polymerization of catalysts.

Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE.
Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

In solution, 2-Sulfanylethanol is readily oxidized in air to a disulfide, especially at alkaline pH. Because of this property, 2-Sulfanylethanol is widely used to protect proteins, enzymes in particular, from becoming inactive.
An excess of 2-Sulfanylethanol (generally used at 0.01 M) will maintain the protein thiol groups in their reduced state.

2-Sulfanylethanol is a potent reducing agent that effectively cleaves and reduces disulfide bonds.
2-Sulfanylethanol disrupts tertiary and quaternary protein structures and is often used to unfold native proteins.

This property makes 2-Sulfanylethanol a useful reagent for preparing samples in denaturing protein electrophoresis, as well as for inactivating ribonucleases during some RNA isolation procedures.
2-Sulfanylethanol has also been used in mammalian cell culture media to prevent toxic levels of oxygen radicals.

2-Sulfanylethanol is an alternative to dithiothreitol (DTT), but DTT is more popular for use in SDS-PAGE as it is less toxic and less reactive.
2-Sulfanylethanol is not stable in solution, so most protocols require daily supplementation.

2-Sulfanylethanol is a clear, colorless to pale yellow liquid with a low viscosity and a sharp, pungent odor often described as similar to rotten eggs, characteristic of compounds containing a thiol (-SH) group.
2-Sulfanylethanol is fully miscible with water, alcohols, ethers, and many polar organic solvents, with a boiling point around 157 °C, a melting point near −98 °C, and a density of approximately 1.11 g/cm³ at 20 °C.
The molecule contains both a hydroxyl (-OH) and a thiol (-SH) functional group, which confer strong nucleophilic, reducing, and chelating properties.

In the biochemical and molecular biology fields, 2-Sulfanylethanol is best known as a potent reducing agent used to cleave disulfide bonds in proteins, thereby preventing the formation of incorrect intramolecular or intermolecular disulfide bridges during experiments.
2-Sulfanylethanol is routinely employed in sample preparation for sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), Western blotting, and enzyme assays, helping maintain proteins in their denatured and fully reduced forms.

In cell culture applications, 2-Sulfanylethanol is added at low concentrations to maintain a reducing environment, enhance cell viability, and prevent oxidative stress.
Additionally, 2-Sulfanylethanol serves as a stabilizer in enzyme formulations, a chain transfer agent in polymerization processes, and a synthetic intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals.

Market Overview of 2-Sulfanylethanol:
The global 2-Sulfanylethanol market is projected to grow steadily over the next decade, with recent estimates placing its 2024 value between USD 80 million and USD 450 million, depending on the reporting scope, and forecasts reaching up to USD 791.9 million by 2034 at compound annual growth rates ranging from 3% to 5.8%.
Growth is driven primarily by 2-Sulfanylethanol's extensive use in biotechnology and pharmaceutical research as a reducing agent for proteins, as well as its role in polymer and rubber manufacturing as a chain-transfer agent.

High-purity grades (≥99%) dominate demand in applications requiring strict quality standards, including biopharma, electronics, and specialty chemicals.
Asia-Pacific leads the global market with over 40% share, supported by strong industrial and research activity, while North America and Europe maintain steady growth through established biotech, pharmaceutical, and industrial sectors.
Emerging applications in water treatment, cosmetics, and agrochemical synthesis are expected to further support demand, ensuring a positive market outlook despite handling and safety challenges associated with 2-Sulfanylethanol’s toxicity and strong odor.

Applications of 2-Sulfanylethanol:
2-Sulfanylethanol is widely applied in biotechnology, pharmaceuticals, and industrial chemistry due to its strong reducing power and dual functional groups.
In molecular biology and biochemical research, 2-Sulfanylethanol is a key reagent for breaking disulfide bonds in proteins and peptides, ensuring they remain in a reduced or denatured state during techniques such as SDS-PAGE, Western blotting, enzyme assays, and protein purification.

In cell culture, low concentrations help maintain a reducing environment, protect cells from oxidative stress, and enhance viability.
2-Sulfanylethanol also stabilizes enzymes by preventing oxidative degradation of active sites, extending their functional lifespan.

In the polymer and rubber industry, 2-Sulfanylethanol serves as a chain-transfer agent in polymerization processes for latex, synthetic rubbers, and specialty polymers, while in chemical synthesis it acts as a nucleophile, intermediate, or catalyst in producing pharmaceuticals, agrochemicals, and fine chemicals.
Additional uses include corrosion inhibition, water treatment, and selected electronics applications, where controlled reduction is required to achieve desired surface or material properties.

Reducing proteins:
Some proteins can be denatured by 2-Sulfanylethanol, which cleaves the disulfide bonds that may form between thiol groups of cysteine residues.

In the case of excess 2-Sulfanylethanol, the following equilibrium is shifted to the right:
RS–SR + 2 HOCH2CH2SH ⇌ 2 RSH + HOCH2CH2S–SCH2CH2OH

By breaking the S-S bonds, both the tertiary structure and the quaternary structure of some proteins can be disrupted.
Because of its ability to disrupt the structure of proteins, 2-Sulfanylethanol was used in the analysis of proteins, for instance, to ensure that a protein solution contains monomeric protein molecules, instead of disulfide linked dimers or higher order oligomers.

However, since 2-Sulfanylethanol forms adducts with free cysteines and is somewhat more toxic, dithiothreitol (DTT) is generally more used especially in SDS-PAGE.
2-Sulfanylethanol is also a more powerful reducing agent with a redox potential (at pH 7) of −0.33 V, compared to −0.26 V for 2-Sulfanylethanol.

Preventing protein oxidation:
2-Sulfanylethanol and related reducing agents (e.g., DTT) are often included in enzymatic reactions to inhibit the oxidation of free sulfhydryl residues, and hence maintain protein activity.
2-Sulfanylethanol is often used in enzyme assays as a standard buffer component.

Denaturing ribonucleases:
2-Sulfanylethanol is used in some RNA isolation procedures to eliminate ribonuclease released during cell lysis.
Numerous disulfide bonds make ribonucleases very stable enzymes, so 2-Sulfanylethanol is used to reduce these disulfide bonds and irreversibly denature the proteins.
This prevents them from digesting the RNA during 2-Sulfanylethanol's extraction procedure.

Deprotecting carbamates:
Some carbamate protecting groups such as carboxybenzyl (Cbz) or allyloxycarbonyl (alloc) can be deprotected using 2-Sulfanylethanol in the presence of potassium phosphate in dimethylacetamide.

2-Sulfanylethanol has a broad range of applications across research, industrial, and specialty chemical sectors, owing to its strong reducing properties and dual functional groups (thiol and hydroxyl):

Biotechnology & Molecular Biology:
2-Sulfanylethanol reduces disulfide bonds in proteins and peptides to maintain them in a denatured or fully reduced state during SDS-PAGE, Western blotting, enzyme assays, and protein purification.

Cell Culture:
Added in low concentrations to culture media to maintain a reducing environment, improve cell viability, and protect against oxidative stress.

Enzyme Stabilization:
2-Sulfanylethanol prevents oxidation of sensitive enzyme active sites, prolonging shelf life and maintaining catalytic activity.

Polymer & Rubber Industry:
2-Sulfanylethanol serves as a chain-transfer agent in polymerization processes for latex, synthetic rubber, and specialty polymers.

Chemical Synthesis:
Functions as a nucleophile, intermediate, or catalyst in the production of pharmaceuticals, agrochemicals, and fine chemicals.

Water Treatment & Corrosion Inhibition:
2-Sulfanylethanol is used in certain formulations for controlling oxidation and corrosion processes.

Electronics Industry:
Applied in cleaning and etching solutions where controlled reduction is required.

Uses of 2-Sulfanylethanol:
2-Sulfanylethanol is commonly used to reduce disulfide bridges present in proteins and can play a role as a biological antioxidant.
2-Sulfanylethanol is also used because of its hydroxyl group, which makes it miscible in water and reduces the volatility (and therefore the odor) of thiol.

2-Sulfanylethanol is a powerful reducing agent used in cell culture media to prevent toxic levels of oxygen radicals.
2-Sulfanylethanol is widely used because the hydroxyl group confers solubility in water and lowers the volatility

Solubilizes proteins by reducing disulfide linkages 2-Sulfanylethanol is used in the preparation of nano-graphene for cellular imaging and drug delivery as well as multifunctional polymeric micelle.
2-Sulfanylethanol acts as a reducing agent used in electrophoresis, amino acid detection, and distinguishing ssDNA/dsDNA.

2-Sulfanylethanol is also employed as a standard buffer.
2-Sulfanylethanol is also used in the preparation of PVC heat stabilizers and as a chain transfer agent in the manufacture of PVC.

Further, 2-Sulfanylethanol is used in some RNA isolation procedures to eliminate ribonuclease.
2-Sulfanylethanol is utilized as a corrosion inhibitor and ore floatation agent.
In biochemistry, 2-Sulfanylethanol is useful to study the activity of the immune system.

Benefits of 2-Sulfanylethanol:
2-Sulfanylethanol offers several benefits that make it valuable in both research and industrial applications.
2-Sulfanylethanol's potent reducing capability enables efficient cleavage of disulfide bonds in proteins and peptides, making it indispensable in molecular biology workflows such as SDS-PAGE and protein purification.

2-Sulfanylethanol’s dual functional groups (thiol and hydroxyl) provide both nucleophilicity and hydrogen-bonding potential, giving it versatility in chemical synthesis and polymer modification.
In cell culture, 2-Sulfanylethanol's antioxidant properties help maintain a reducing environment, improve cell viability, and protect against oxidative stress.

As an enzyme stabilizer, 2-Sulfanylethanol prevents oxidation of sensitive active sites, prolonging shelf life and maintaining activity.
In polymerization, 2-Sulfanylethanol's role as a chain-transfer agent allows control over molecular weight and polymer structure, enhancing material performance.
Additionally, 2-Sulfanylethanol's broad solubility in water and organic solvents ensures compatibility across diverse formulations, from biopharmaceuticals to industrial coatings, making it a multifunctional reagent in numerous fields.

Production of 2-Sulfanylethanol:
Industrial production of 2-Sulfanylethanol is typically carried out by the reaction of ethylene oxide with hydrogen sulfide (H₂S) in the presence of an acid or base catalyst.
In the most common process, gaseous ethylene oxide is introduced into a reactor containing hydrogen sulfide under controlled temperature and pressure conditions.

The reaction proceeds via nucleophilic ring-opening of ethylene oxide by hydrogen sulfide, producing 2-hydroxyethyl mercaptan (2-Sulfanylethanol) as the primary product.
Catalysts such as sodium hydroxide or acidic ion-exchange resins can be used to enhance reaction rates and selectivity.

After synthesis, the crude product is separated from unreacted feedstocks and by-products (such as ethylene glycol or dihydroxyethyl sulfide) through distillation, often under reduced pressure to prevent decomposition.
Modern plants use continuous processing systems to maintain high yields, minimize impurities, and reduce occupational exposure to toxic hydrogen sulfide gas.

An alternative route involves the addition of hydrogen sulfide to ethylene chlorohydrin, but this method is less common today due to the handling hazards and waste disposal challenges associated with chlorinated intermediates.
The ethylene oxide–hydrogen sulfide process remains the industry standard because of 2-Sulfanylethanol's high efficiency, relatively simple purification, and ability to produce material in both industrial and high-purity grades suitable for biochemical applications.

History of 2-Sulfanylethanol:
The history of 2-Sulfanylethanol dates back to the mid-20th century, when advances in organosulfur chemistry and large-scale petrochemical synthesis created demand for multifunctional thiol compounds.
2-Sulfanylethanol's development was closely tied to the expansion of ethylene oxide chemistry in the 1940s and 1950s, as manufacturers explored ways to produce value-added derivatives from inexpensive ethylene feedstocks.

Early synthetic methods, such as the reaction of ethylene chlorohydrin with hydrogen sulfide, were used in laboratory settings but proved inefficient and generated significant waste.
By the 1950s, the ethylene oxide–hydrogen sulfide catalytic process was established, offering a cleaner, higher-yield route that quickly became the industrial standard.

Initially, 2-Sulfanylethanol found niche applications as a chemical intermediate and polymer additive, particularly in the rubber and plastics industries where it served as a chain-transfer agent.
2-Sulfanylethanol's breakthrough into the biochemical field came in the 1960s and 1970s, when researchers discovered its effectiveness as a reducing agent for disulfide bonds in proteins, enabling major improvements in protein electrophoresis, enzyme stabilization, and molecular biology techniques.
As life sciences expanded in the late 20th century, demand for high-purity grades of 2-Sulfanylethanol increased sharply, cementing its role in biotechnology, pharmaceutical R&D, and academic research.

Today, while 2-Sulfanylethanol's basic manufacturing route remains largely unchanged from the processes refined in the mid-20th century, production is carried out in modern, closed-loop systems with enhanced safety, environmental controls, and high-purity refining methods, reflecting decades of technological and regulatory evolution.

Handling and Storage of 2-Sulfanylethanol:

Handling:
Use only in a well-ventilated area or chemical fume hood to avoid inhalation of vapors.
Avoid all contact with skin, eyes, and clothing.

Prevent inhalation of vapors or mist.
Keep away from heat, sparks, open flames, and sources of ignition.
Do not eat, drink, or smoke when handling.

Storage:
Store in tightly closed, corrosion-resistant containers in a cool (2–8 °C), dry, well-ventilated location.
Keep away from oxidizing agents, acids, and strong bases.
Protect from moisture and direct sunlight.

Stability and Reactivity of 2-Sulfanylethanol:

Chemical Stability:
Stable under recommended storage conditions.

Possible Hazardous Reactions:
No hazardous polymerization expected.

Conditions to Avoid:
Heat, flames, sparks, prolonged exposure to air (oxidation), and incompatible chemicals.

Incompatible Materials:
Strong oxidizers (e.g., nitric acid, hydrogen peroxide), strong bases, acids, and metal salts.

Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, sulfur oxides, and other toxic sulfur compounds.

First Aid Measures of 2-Sulfanylethanol:

Inhalation:
Remove to fresh air immediately.
If breathing is difficult, administer oxygen.
Seek medical attention promptly.

Skin Contact:
Remove contaminated clothing and wash skin with soap and plenty of water for at least 15 minutes.
Seek medical advice if irritation occurs.

Eye Contact:
Rinse cautiously with water for several minutes, removing contact lenses if present and easy to do.
Continue rinsing for at least 15 minutes and get immediate medical attention.

Ingestion:
Rinse mouth with water.
Do not induce vomiting.
Seek immediate medical attention.

Firefighting Measures of 2-Sulfanylethanol:

Suitable Extinguishing Media:
Use water spray, foam, dry chemical, or carbon dioxide.

Specific Hazards:
Vapors are flammable and heavier than air, may form explosive mixtures with air.
Combustion releases toxic sulfur-containing fumes.

Protective Equipment for Firefighters:
Wear self-contained breathing apparatus (SCBA) and full protective gear.
Cool fire-exposed containers with water spray.

Accidental Release Measures of 2-Sulfanylethanol:

Personal Precautions:
Evacuate area.
Use PPE including gloves, goggles, and respirator.
Avoid inhalation of vapors.

Environmental Precautions:
Prevent spills from entering drains, waterways, or soil.
Notify authorities in case of large releases.

Spill Cleanup:
Contain and absorb with inert materials (e.g., vermiculite, sand).
Collect in suitable labeled containers for disposal.
Ventilate area after cleanup.

Exposure Controls / Personal Protective Equipment of 2-Sulfanylethanol:

Engineering Controls:
Use chemical fume hood or local exhaust ventilation to keep airborne concentrations below exposure limits (OSHA TWA: 0.2 ppm; ACGIH TLV: 0.2 ppm).

Respiratory Protection:
If exposure limits may be exceeded, use NIOSH-approved respirator with organic vapor cartridges.

Hand Protection:
Wear chemical-resistant gloves (e.g., nitrile, neoprene).

Eye Protection:
Safety goggles or full face shield.

Skin/Body Protection:
Lab coat or chemical-resistant suit, with closed footwear.

Hygiene Measures:
Wash hands thoroughly after handling.
Remove and wash contaminated clothing before reuse.

Identifiers of 2-Sulfanylethanol:
Molecular Formula: C₂H₆OS
Molecular Weight: 78.13 g/mol
CAS Number: 60-24-2
EC Number (EINECS): 200-464-6
PubChem CID: 1567
ChemSpider ID: 1502

InChI: InChI=1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
InChI Key: LQEXIORDWJAHNM-UHFFFAOYSA-N
Canonical SMILES: C(CS)O

Chemical Name: 2-Sulfanylethanol
Molecular Formula: C₂H₆OS
Molecular Weight: 78.13 g/mol
CAS Number: 60-24-2
EC Number (EINECS): 200-464-6
PubChem CID: 1567
ChemSpider ID: 1502
Beilstein Registry Number: 1098253
RTECS Number: KL5600000
Merck Index Number: 6106

InChI: InChI=1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
InChI Key: LQEXIORDWJAHNM-UHFFFAOYSA-N
Canonical SMILES: C(CS)O
Isomeric SMILES: C(CS)O

Properties of 2-Sulfanylethanol:
Chemical Name: 2-Sulfanylethanol
Molecular Formula: C₂H₆OS
Molecular Weight: 78.13 g/mol
Appearance: Clear, colorless to pale yellow liquid
Odor: Strong, unpleasant odor (rotten eggs/garlic-like, typical of thiols)
Taste: Not applicable (toxic)

Density: 1.114 g/cm³ at 20 °C
Melting Point: −98 °C
Boiling Point: ~157 °C at 1013 hPa
Flash Point: 74 °C (closed cup)
Autoignition Temperature: ~295 °C
Vapor Pressure: ~0.11 hPa at 25 °C
Refractive Index (n²⁰D): ~1.493–1.495
Viscosity: ~5.0 mPa·s at 25 °C
pKa: ~9.64 (thiol group)
Odor Threshold: Extremely low (~0.0002 ppm; detectable at trace levels)

Chemical Name: 2-Sulfanylethanol
Molecular Formula: C₂H₆OS
Molecular Weight: 78.13 g/mol
Appearance: Clear, colorless to pale yellow liquid
Odor: Strong, unpleasant “rotten egg” or garlic-like odor (thiol)
Molar Volume: ~70.1 cm³/mol
Molar Refractivity: ~26.3 cm³

Density: 1.114 g/cm³ at 20 °C
Melting Point: −98 °C
Boiling Point: ~157 °C at 101.3 kPa
Flash Point: 74 °C (closed cup)
Autoignition Temperature: 295 °C
Vapor Pressure: 0.11 hPa at 25 °C
Viscosity: ~5.0 mPa·s at 25 °C
Surface Tension: ~45.2 mN/m at 20 °C
Refractive Index (n²⁰D): 1.493–1.495
Odor Threshold: ~0.0002 ppm (extremely low detection level)

Molecular Weight: 78.14
XLogP3-AA: -0.2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 78.01393598
Monoisotopic Mass: 78.01393598
Topological Polar Surface Area: 21.2 Å²
Heavy Atom Count: 4
Complexity: 10
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Color/Form: Water-white mobile liquid
Odor: Strong disagreeable odor
Henry's Law constant = 1.3X10-7 atm-cu m/mol at 25 °C (est)
Autoignition Temperature: 295 °C
Decomposition: When heated to decomposition it emits highly toxic fumes of /sulfur oxides/.
Viscosity: 3.43 cP