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3,5-Dimethylpyrazole is a heterocyclic organic compound consisting of a five-membered pyrazole ring substituted with two methyl groups at the 3 and 5 positions.
3,5-Dimethylpyrazole is widely used as an intermediate in the synthesis of agrochemicals, pharmaceuticals, corrosion inhibitors, and polymer additives.
3,5-Dimethylpyrazole is known for its nucleophilic properties and ability to form stable complexes with metals.
CAS Number: 67-51-6
EC Number: 200-650-8
Molecular Formula: C5H8N2
Molecular Weight: 96.13 g/mol
Synonyms: 3,5-Dimethylpyrazole, 1H-Pyrazole, 3,5-dimethyl-, Dimethylpyrazole, DMP, Pyrazole, 3,5-dimethyl-, 3,5-Dimethyl-1H-pyrazole, DMPZ, Pyrazole Dimethyl Substituted, Agrochemical Intermediate DMP, 3,5-Dimethylpyrazole Monomer, Pyrazole Derivative, 3,5-Dimethyl-Pyrazole
APPLICATIONS
3,5-Dimethylpyrazole is used in the manufacture of plant protection agents such as nitrification inhibitors for fertilizers.
3,5-Dimethylpyrazole is employed in the synthesis of triazole-based fungicides and herbicides.
3,5-Dimethylpyrazole is found in crop protection products where it slows the conversion of ammonium to nitrate in soil.
3,5-Dimethylpyrazole is used in pharmaceutical intermediates for the development of anti-inflammatory and antitumor agents.
3,5-Dimethylpyrazole is incorporated into drug discovery pipelines as a scaffold for heterocyclic synthesis.
3,5-Dimethylpyrazole is applied in the production of pyrazole-based ligands for coordination chemistry.
3,5-Dimethylpyrazole is used as a corrosion inhibitor in industrial metal protection systems.
3,5-Dimethylpyrazole is used in water treatment and oilfield applications to inhibit metal oxidation and degradation.
3,5-Dimethylpyrazole is found in metalworking fluids to prolong tool life and reduce corrosion.
3,5-Dimethylpyrazole is used as a building block in the synthesis of polymerization catalysts.
3,5-Dimethylpyrazole is used as a stabilizer in polyurethane foams and resins.
3,5-Dimethylpyrazole is found in specialty coatings and adhesives for enhanced thermal stability.
3,5-Dimethylpyrazole is employed in the synthesis of energetic materials and advanced propellant formulations.
3,5-Dimethylpyrazole is applied in analytical chemistry as a reagent or complexing agent.
3,5-Dimethylpyrazole is used in dye and pigment synthesis for introducing nitrogen-rich functional groups.
3,5-Dimethylpyrazole is found in research laboratories for organic synthesis and heterocycle development.
3,5-Dimethylpyrazole is used in experimental medicinal chemistry to evaluate biological activity in enzyme inhibitors.
3,5-Dimethylpyrazole is applied in polymer science to modify crosslinking behavior.
3,5-Dimethylpyrazole is used as a blocking agent in polyurethane systems to control reaction timing.
3,5-Dimethylpyrazole is employed in the synthesis of agrochemicals for its heterocyclic structure.
3,5-Dimethylpyrazole is used as an intermediate in the production of pharmaceuticals.
3,5-Dimethylpyrazole is utilized in corrosion inhibitors for industrial coatings.
3,5-Dimethylpyrazole is used in research as a ligand in coordination chemistry.
3,5-Dimethylpyrazole is incorporated into the formulation of controlled-release fertilizers.
3,5-Dimethylpyrazole is applied in gas-phase reactions as a nitrogen-containing building block.
3,5-Dimethylpyrazole is used in the synthesis of dyes and colorants.
3,5-Dimethylpyrazole is utilized as a stabilizer in specialty resins.
3,5-Dimethylpyrazole is used in the design of herbicides and plant growth regulators.
3,5-Dimethylpyrazole is incorporated into analytical reagents for chemical detection.
3,5-Dimethylpyrazole is used in the formulation of fungicides for crop protection.
3,5-Dimethylpyrazole is employed in catalyst systems for polymerization reactions.
3,5-Dimethylpyrazole is used in the development of flame retardant additives.
3,5-Dimethylpyrazole is added to paints and coatings for enhanced chemical resistance.
3,5-Dimethylpyrazole is used as a raw material for heterocyclic compound libraries.
3,5-Dimethylpyrazole is applied in the electronics industry in anti-static materials.
3,5-Dimethylpyrazole is used in the development of specialty lubricants and greases.
3,5-Dimethylpyrazole is included in industrial adhesives for enhanced durability.
3,5-Dimethylpyrazole is used in rubber processing aids to improve vulcanization.
3,5-Dimethylpyrazole is employed in solvent formulations for niche industrial applications.
3,5-Dimethylpyrazole is used in fragrance intermediates for specialty aroma compounds.
3,5-Dimethylpyrazole is incorporated into anti-aging additives for polymers.
3,5-Dimethylpyrazole is used in metal complexation studies for new material development.
3,5-Dimethylpyrazole is used in laboratory research for synthesis of functionalized pyrazoles.
3,5-Dimethylpyrazole is utilized in UV-curable coatings as a nitrogen donor.
3,5-Dimethylpyrazole is found in epoxy systems to tailor reactivity and curing profiles.
3,5-Dimethylpyrazole is used in hydrogel chemistry as a crosslinking agent.
3,5-Dimethylpyrazole is applied in textile auxiliaries for finishing treatments.
3,5-Dimethylpyrazole is used in anti-foaming agents for polymer emulsions.
3,5-Dimethylpyrazole is a heterocyclic compound with the formula C5H8N2.
3,5-Dimethylpyrazole appears as a white to off-white crystalline powder with a characteristic odor.
3,5-Dimethylpyrazole is a substituted pyrazole with two methyl groups at positions 3 and 5.
3,5-Dimethylpyrazole exhibits moderate polarity and is soluble in organic solvents.
3,5-Dimethylpyrazole is thermally stable and often used in applications requiring high heat resistance.
3,5-Dimethylpyrazole can act as a nitrogen donor ligand in organometallic chemistry.
3,5-Dimethylpyrazole is known for its blocking ability in isocyanate-based systems.
3,5-Dimethylpyrazole is relatively low in toxicity but should be handled with proper protection.
DESCRIPTION
3,5-Dimethylpyrazole is a white to off-white crystalline solid with a faint aromatic or amine-like odor.
3,5-Dimethylpyrazole is a pyrazole derivative containing two methyl groups that influence its electron density and steric properties.
3,5-Dimethylpyrazole exhibits weak basicity and participates in hydrogen bonding due to its N-H group.
3,5-Dimethylpyrazole is soluble in organic solvents such as ethanol, methanol, acetone, and chloroform.
3,5-Dimethylpyrazole is moderately soluble in water and forms clear solutions under standard conditions.
3,5-Dimethylpyrazole can undergo electrophilic substitution and nucleophilic addition reactions.
3,5-Dimethylpyrazole is thermally stable under ambient storage but may degrade under strong oxidative conditions.
3,5-Dimethylpyrazole shows low volatility and has a relatively high melting point for a heterocycle of its size.
3,5-Dimethylpyrazole is not classified as a hazardous material under normal use but should be handled with care.
3,5-Dimethylpyrazole reacts with acylating and alkylating agents to form derivatives useful in medicinal chemistry.
3,5-Dimethylpyrazole is structurally rigid and offers a good platform for the development of functionalized molecules.
3,5-Dimethylpyrazole is often used in conjunction with other nitrogen-containing heterocycles in synthetic applications.
3,5-Dimethylpyrazole is a versatile intermediate for pharmaceuticals and industrial chemistry.
3,5-Dimethylpyrazole has a melting point of approximately 108–110°C and a molecular weight of 96.13 g/mol.
PROPERTIES
Chemical Formula: C5H8N2
Molecular Weight: 96.13 g/mol
Common Name: 3,5-Dimethylpyrazole
Appearance: White to off-white crystalline powder
Odor: Mild, aromatic or amine-like
Melting Point: ~108–110°C
Boiling Point: ~233°C
Flash Point: ~110°C (closed cup)
Solubility: Soluble in organic solvents; slightly soluble in water
Density: ~1.05 g/cm³
pKa: ~13.5 (for NH group)
Reactivity: Reacts with acids, electrophiles, and metal salts
Storage Conditions: Store in a cool, dry, well-ventilated area
Stability: Stable under recommended storage; avoid strong oxidizers
FIRST AID
Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory symptoms persist.
Avoid inhaling powders or fumes.
Skin Contact:
Wash affected area with soap and water.
Remove contaminated clothing and rinse skin.
Seek medical attention if irritation develops.
Eye Contact:
Flush eyes with water for at least 15 minutes.
Remove contact lenses if present.
Seek medical attention for persistent redness or pain.
Ingestion:
Rinse mouth thoroughly with water.
Do not induce vomiting unless instructed by a healthcare professional.
Seek medical advice if large amounts are swallowed.
Note to Physicians:
Treat symptomatically based on clinical presentation.
No specific antidote known.
Supportive care is recommended for large exposures.
HANDLING AND STORAGE
Handling:
Wear protective gloves, goggles, and appropriate clothing.
Avoid inhalation of dust and contact with skin and eyes.
Do not eat, drink, or smoke while handling the material.
Ventilation:
Use in a well-ventilated area or under fume hood.
Minimize airborne dust generation.
Storage:
Store in tightly sealed containers in a cool, dry, well-ventilated area.
Avoid heat, moisture, and direct sunlight.
Keep away from incompatible substances such as strong oxidizers.
Spill and Leak Procedures:
Sweep up and collect spilled material in a dry container.
Avoid raising dust during cleanup.
Dispose of according to local environmental regulations.
Handling Precautions:
Label containers properly and keep them sealed when not in use.
Ensure emergency eyewash stations and safety showers are accessible.
Follow standard laboratory hygiene and safety procedures.
