PRODUCTS

3-BROMO-PROPEN

3-bromo-propen is used as a precursor for the preparation of allyliczinc bromide by reacting it with zinc.
3-bromo-propen is also used in the preparation of allylethers like allyl decyl ether, allyl benzyl ether, and allyl geranyl ether.
3-bromo-propen is also used in the preparation of R enantiomer of allyl phenyl carbinol (APC), such as 1-phenyl-3-butene, which is a valuable intermediate for drugs and agro-chemicals.

CAS Number: 106-95-6
EC Number: 203-446-6
Hill Formula:C₃H₅Br
Chemical Formula:BrCH₂CH=CH₂
Molar Mass: 120.98 g/mol

SYNONYMS:
Allyl bromide, 3-Bromo-1-propene, Allyl bromide, 3-BROMOPROPENE, 3-BROMO-1-PROPENE, 3-bromopropane, 3-BROMOPROPYLENE, Allylbromid, BROMALLYLENE, 3-Brompropen, 3-bromo-prop-1-ene, CH2=CHCH2Br, ALLYL BROMIDE, Propene, 3-bromo-, Allyl bromide, 1-Bromo-2-propene, 2-Propenyl bromide, 3-Bromo-1-propene, 3-Bromopropene, 3-Bromopropylene, CH2=CHCH2Br, Bromallylene, UN 1099, NSC 7596, 3‑Bromo‑1‑propene, 3‑Bromopropene, 3‑Bromopropylene, 2‑Propenyl bromide, bromoallylene, allyl bromide, propene,3‑bromo‑, BROMALLYLENE, ALLYLBROMIDE, Allyl bromide, ALLYL BROMIDE, 3-Bromopropene, 3-BROMOPROPENE, 3-Bromo Propene, 3-bromopropylene, 3-BROMOPROPYLENE, Propene, 3-bromo-, 3-BROMO-1-PROPENE, 3-bromoprop-1-ene, 3-Bromo-1-propene, 2-PROPENYL BROMIDE, 3-Bromoprop-1-ene, Allyl bromide, 3-Bromopropene, 3-Bromopropylene, 3-Bromo-1-propene, Bromoallylene, 2-Propenyl bromide, ALLYL BROMIDE, 106-95-6, 3-Bromopropene, 3-Bromo-1-propene, 3-Bromopropylene, Bromallylene, 2-Propenyl bromide, 1-Bromo-2-propene, Propene, 3-bromo-, NSC 7596, CCRIS 9049, HSDB 622, UNII-FXQ8X2F74Z, EINECS 203-446-6, FXQ8X2F74Z, BRN 0605308, DTXSID8024442, AI3-52208, NSC-7596, DTXCID204442, EC 203-446-6, 203-446-6, 3-bromoprop-1-ene, 1-Propene, 3-bromo-, allylbromide, MFCD00000244, Allyl Bromide (Stabilized with Propylene Oxide), UN1099, allylbromid, allyl bromine, allyl-bromide, 3-bromo-propene, 1-brom-2-propene, 3-bromo-1-propen, UN 1099, 3-bromo-prop-1-ene, CH2=CHCH2Br, SCHEMBL411, ALLYL BROMIDE [MI], 3-Bromopropene Allyl bromide, SCHEMBL26132, ALLYL BROMIDE [HSDB], WLN: E2U1, SCHEMBL299368, SCHEMBL887973, SCHEMBL5494851, CHEMBL1429506, NSC7596, STR00178, Tox21_200801, BR1119, SBB059929, STL199163, AKOS000118756, NCGC00091515-01, NCGC00091515-02, NCGC00258355-01, Allyl bromide, purum, >=98.0% (GC), BP-13477, CAS-106-95-6, Allyl bromide, puriss., >=99.0% (GC), B0643, NS00008702, ST51046196, Allyl bromide [UN1099] [Flammable liquid], EN300-19278, InChI=1/C3H5Br/c1-2-3-4/h2H,1,3H, Q223062, F2190-0178, Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide, Allyl bromide, reagent grade, 97%, contains <=1000 ppm propylene oxide as stabilizer, Allyl bromide, ReagentPlus(R), 99%, contains <=1000 ppm propylene oxide as stabilizer, 3-bromo-1-propene, 106-95-6, 3-bromo-prop-1-ene, 3-bromoprop-1-ene, 3-bromprop-1-en

3-bromo-propen is an organic halide.
3-bromo-propen is an alkylating agent used in synthesis of polymers, pharmaceuticals, perfumes, and other organic compounds.
3-bromo-propen is a colorless liquid, although commercial samples appear yellow or brown.

3-bromo-propen is an irritant and a potentially dangerous alkylating agent.
3-bromo-propen is more reactive but more expensive than allyl chloride, and these considerations guide its use.
3-bromo-propen appears as a clear colorless to light yellow liquid with an irritating unpleasant odor.

Flash point of 3-bromo-propen is 30 °F.
3-bromo-propen is denser than water and slightly soluble in water.
3-bromo-propen is an alkyl bromide.

3-bromo-propen has been described as an insecticidal fumigant used in crop protection.
Physically, 3-bromo-propen is a clear liquid with an intense, acrid, and persistent smell.
3-bromo-propen appears as a clear colorless to light yellow liquid with an irritating unpleasant odor.

Flash point of 3-bromo-propen is30 °F.
3-bromo-propen is denser than water and slightly soluble in water.
3-bromo-propen is slightly soluble in water.

USES and APPLICATIONS of 3-BROMO-PROPEN:
3-bromo-propen is used as an alkylating agent in the synthesis of pharmaceuticals, polymers, adhesives, perfumes, biochemicals, and other allylic compounds.
3-bromo-propen is used as a precursor for the preparation of allyliczinc bromide by reacting it with zinc.

3-bromo-propen is also used in the preparation of allylethers like allyl decyl ether, allyl benzyl ether, and allyl geranyl ether.
3-bromo-propen is also used in the preparation of R enantiomer of allyl phenyl carbinol (APC), such as 1-phenyl-3-butene, which is a valuable intermediate for drugs and agro-chemicals.

3-bromo-propen is primarily used as a starting material/chemical intermediate in organic synthesis.
3-bromo-propen is also used as an intermediate in the manufacture of polymers/resins, synthetic perfumes, pharmaceuticals, agricultural chemicals, and other allyl compounds.

3-bromo-propen has been described as an insecticidal fumigant used in crop protection.
3-bromo-propen is used as an alkylating agent in the synthesis of pharmaceuticals, polymers, adhesives, perfumes, biochemicals, and other allylic compounds.

3-bromo-propen is also used in the preparation of R enantiomer of allyl phenyl carbinol (APC), such as 1-phenyl-3-butene, which is a valuable intermediate for drugs and agro-chemicals.
Organic synthesis & alkylation: 3-bromo-propen serves as an electrophilic alkylating agent and a key intermediate in preparing allylic derivatives (e.g., pharmaceuticals like methohexital, secobarbital, polymers, and perfumes)

Grignard reagent precursor: 3-bromo-propen converts to allyl‑magnesium bromide for carbon–carbon bond formation
Polymer research: 3-bromo-propen is used in advanced materials applications, including photo‑regulated adsorption systems
3-bromo-propen is used as a pharmaceutical intermediate

3-bromo-propen is used in organic synthesis such as synthetic dyes, fragrances
3-bromo-propen is used in the pharmaceutical industry for the manufacture of cicatriasis
3-bromo-propen is used agricultural use as a soil fumigant

Organic synthesis, pharmaceutical synthesis intermediates, 3-bromo-propen can be used for the synthesis of the West of barbiturates, dyes, spices
3-bromo-propen is used agriculture for soil fumigation

3-bromo-propen is also used as an intermediate for resin modification and fragrance synthesis, household chemicals, emulsion modifiers, silicon products, etc.
3-bromo-propen has been reported that the polymer that can be polymerized with plasma to form reverse osmosis wax is used in a sealed manned.

3-bromo-propen can also be used as a corrosion inhibitor, catalyst and solvent
3-bromo-propen is used in organic synthesis, and can be used as synthetic dyes and spices
The pharmaceutical industry is used for the preparation of the drug "ceobarbitone"

3-bromo-propen is used agriculture is used as a soil fumigant
3-bromo-propen is used for organic synthesis, can be used for synthetic dyes, spices
Pharmaceutical industry, 3-bromo-propen is used for the preparation of "Western barbiturates" drugs

3-bromo-propen is used agriculture used as soil fumigant
3-bromo-propen is used as pharmaceutical intermediates
3-bromo-propen is used as an alkylating agent in the synthesis of pharmaceuticals, polymers, adhesives, perfumes, biochemicals and other allylic compounds.

3-bromo-propen is used as a precursor for the preparation of allylic zinc bromide by reacting it with zinc.
3-bromo-propen is also used in the preparation of allyl ethers like allyl decyl ether, allyl benzyl ether and allyl geranyl ether.
3-bromo-propen is also used in the preparation of R enantiomer of allyl phenyl carbinol (APC) such as 1-phenyl-3-butene, which is a valuable intermediate for drugs and agro-chemicals.

3-bromo-propen can be used as a reagent to prepare: Allyl ketones by Barbier-type allylation of various nitriles in the presence of Lewis acid.
Homoallylic alcohols by reacting with aldehydes or ketones using zinc dust as a catalyst.
1,5-hexadiene by reductive C–C bond coupling using silver hydride cluster.

REACTIONS AND USES OF 3-BROMO-PROPEN:
3-bromo-propen is an electrophilic alkylating agent.
3-bromo-propen reacts with nucleophiles, such as amines, carbanions, alkoxides, etc., to introduce the allyl group:
CH₂=CHCH₂Br + Nu⁻ → CH₂=CHCH₂Nu + Br⁻ (Nu⁻ is a nucleophile)

3-bromo-propen is used in the synthesis of compounds containing the allyl functionality, such as the pharmaceuticals methohexital, secobarbital, and thiamylal.
3-bromo-propen reacts with magnesium metal in dry ether to form allylmagnesium bromide, a Grignard reagent:
CH₂=CHCH₂Br + Mg → CH₂=CHCH₂MgBr

BENEFITS & CHARACTERISTICS OF 3-BROMO-PROPEN:
Highly reactive allyl donor – ideal for introducing allylic functionality into organic molecules
Versatile intermediate in pharmaceutical, agrochemical, fragrance and materials synthesis
Precursor to Grignard reagents: valuable in carbon–carbon bond-forming reactions

USAGE & SAFETY RECOMMENDATIONS OF 3-BROMO-PROPEN:
Use 3-bromo-propen only in well‑ventilated chemical fume hoods; vapors heavier than air can accumulate at floor level.
Wear PPE: chemical-resistant gloves (Viton), goggles/face shield, flame-resistant lab coat.
Use full‑face respirators if airborne levels exceed TLVs.

Control exposure: monitor TLVs, ensure local exhaust ventilation, avoid ignition sources.
Waste disposal: treat as hazardous chemical waste—do not discharge to drains; consult local regulations.

Emergency response: for spills, extinguish ignition sources, ventilate, absorb and collect waste.
In case of fire, use CO₂, dry powder, foam; avoid high-pressure water jets.

SOLUBILITY OF 3-BROMO-PROPEN:
3-bromo-propen is slightly miscible with water.

NOTES OF 3-BROMO-PROPEN:
3-bromo-propen is Moisture and light sensitive.
3-bromo-propen is incompatible with oxidizing agents, alkali metals, alkaline earth metals, amides, amines, and powdered metals.

CHEMICAL PROPERTIES OF 3-BROMO-PROPEN:
3-bromo-propen is a flammable liquid with an intense, acrid, persistent smell.
3-bromo-propen is insoluble in water but soluble in alcohol, ether, acetone, carbon tetrachloride, and chloroform.
3-bromo-propen is used to synthesize other allyl compounds, to synthesize dyestuff and spice, and as a curative in the medicine industry.

3-bromo-propen has a very high mobility in soil.
3-bromo-propen is also used as a soil fumigant and as a contact poison.
3-bromo-propen induces unscheduled DNA synthesis in HeLa cells.

STORAGE OF 3-BROMO-PROPEN:
3-bromo-propen should be stored separate from oxidizing materials and alkalis in a cool, dry, well-ventilated location in tightly closed containers.

PURIFICATION METHODS OF 3-BROMO-PROPEN:
Wash 3-bromo-propen the bromide with NaHCO₃ solution then distilled water, dry (CaCl₂ or MgSO₄), and fractionally distil.
Protect 3-bromo-propen from strong light.

STABILITY & REACTIVITY OF 3-BROMO-PROPEN:
Stable under normal conditions in airtight containers
Incompatible with: strong oxidizers, bases, acids (H₂SO₄), boron trifluoride, aluminum chloride — may cause exothermic polymerization

PREPARATION OF 3-BROMO-PROPEN:
Hydrohalogenation
3-bromo-propen is produced commercially from allyl alcohol and hydrobromic acid:
CH₂=CHCH₂OH + HBr → CH₂=CHCH₂Br + H₂O

3-bromo-propen can also be prepared by the halogen-exchange reaction between allyl chloride and hydrobromic acid.
3-bromo-propen can also be prepared by the allylic bromination of propene.

SYNTHESIS OF 3-BROMO-PROPEN:
Allyl alcohol was synthesized from glycerol and formic acid under inert atmosphere, hydrolysed with NaOH and fractionally distilled to yield the 73% allyl alcohol water azeotrope.

This was then reacted with 48% hydrobromic acid and sulfuric acid and the 3-bromo-propen distilled as per the conventional method.
3-bromo-propen was then redistilled with 3A molecular sieves drying agent to yield the final product which is stored over additional 3A molecular sieves.

PRODUCTION METHOD OF 3-BROMO-PROPEN:
Obtained by bromination of allyl alcohol: hydrobromic acid was fed into a reaction tank, and sulfuric acid and allyl alcohol were added under stirring.

The temperature was heated to reflux for 2 h, and the distillate was distilled off when heated to 8 °C, and the 68–73 °C fraction was collected.
After washing with water, dehydration with anhydrous sodium sulfate and filtration, allyl bromide was obtained.
Bromination of propylene.

REACTIVITY PROFILE OF 3-BROMO-PROPEN:
3-bromo-propen decomposes upon heating and exposure to light, forming HBr (a strong reducing agent).
3-bromo-propen reacts violently with oxidizing agents.

3-bromo-propen can react exothermically with reducing agents to release hydrogen gas.
In the presence of various catalysts (such as acids) or initiators, 3-bromo-propen may undergo exothermic addition polymerization reactions.

PHYSICAL and CHEMICAL PROPERTIES of 3-BROMO-PROPEN:
Molecular formula: C₃H₅Br; Molecular weight: 120.98 g/mol
Appearance: Colorless to light yellow liquid with a pungent, irritating odor
Density: ~1.398 g/cm³ (20 °C); 1.428–1.432 g/cm³ (20 °C, Sigma)
Melting point: −119 °C
Boiling point: ~70–72 °C at 1 atm
Vapor pressure: ~18.6 kPa at 20 °C; ~153 mmHg (~20 kPa)
Solubility in water: ~0.38 g/100 g H₂O (≈3.8 g/L)
Refractive index: 1.4697 (589 nm, 20 °C)

Viscosity: ~0.471 cP
Log P₀ (octanol/water): ~1.56–1.79
Dipole moment: ~1.9 D
Heat of vaporization: ~32.7 kJ/mol
Heat of formation: ΔH_f⁰ (liquid) ~12–20 kJ/mol; (gas) ~45–47 kJ/mol
Critical temperature: ~540–544 K
Flash point: −2 to −1 °C (CC)
Auto‑ignition temperature: ~280–295 °C
Explosive limits: 4.3–7.3 % (v/v in air)

Color: colorless
Odor: No data available
Melting point/freezing point: Melting point: -119 °C
Initial boiling point and boiling range: 71.3 °C at 1.013,25 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 7.3 %(V)

Lower explosion limit: 4.4 %(V)
Flash point: -1 °C - closed cup - c.c.
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: 3.84 g/l at 25 °C
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1.42 g/cm³ at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.

Oxidizing properties: none
Other safety information: No data available
CAS number: 106‑95‑6
EC (EINECS) number: 203‑446‑6
PubChem CID: 7841
ChemSpider: 7553
Compound Canonicalized: Yes

CAS No.: 106‑95‑6
EC No.: 203‑446‑6
Mol. Formula: C₃H₅Br
Mol. Weight: 120.98
Boiling pt.: ~70–72 °C
Density (20 °C): ~1.40 g/m³
Solubility: ~3.8 g/L water
Flash point: –2 to –1 °C

TLV: 0.1 ppm
CAS: 106‑95‑6
EINECS: 203‑446‑6
InChI: InChI=1/C3H5Br/c1-2-3-4/h2H,1,3H2
InChIKey: BHELZAPQIKSEDF-UHFFFAOYSA-N
Molecular Formula: C₃H₅Br
Molar Mass: 120.98
Density: 1.398 g/mL at 25 °C (lit.)
Melting Point: -119 °C
Boiling Point: 70–71 °C (lit.)

Flash Point: 28 °F
Water Solubility: Insoluble
Vapor Pressure: 18.66 kPa at 25 °C
Vapor Density: 4.2 (vs air)
Appearance: Liquid
Specific Gravity: 1.398
Color: Clear colorless to slightly colored
Odor: Unpleasant

Exposure Limit: ACGIH: TWA 0.1 ppm; STEL 0.2 ppm (Skin)
Merck: 14,288
BRN: 605308
Storage Condition: 2–8 °C
Stability: Stable. Flammable. Incompatible with strong oxidizing agents.
Sensitive: Light Sensitive
Explosive Limit: 4.3–7.3 %(V)
Refractive Index: n20/D 1.469 (lit.)

Physical and Chemical Properties
Boiling Point: 70–71 °C
Melting Point: –119 °C
Density: 1.39
Chemical Formula: C₃H₅Br
Molar Mass: 120.977 g·mol⁻¹
Appearance: Clear to light yellow liquid
Odor: Unpleasant, irritating, pungent
Density: 1.398 g/cm³

Melting Point: −119 °C (−182 °F; 154 K)
Boiling Point: 71 °C (160 °F; 344 K)
Solubility in Water: 0.38 g/100 g H₂O
log P: 1.79
Vapor Pressure: 18.6 kPa
Magnetic Susceptibility (χ): −58.6·10⁻⁶ cm³·mol⁻¹
Refractive Index (nD): 1.4697 (20 °C, 589.2 nm)
Viscosity: 0.471 cP

Dipole Moment: ≈1.9 D
Thermochemistry
Std Enthalpy of Formation (ΔfH⦵298): 12.2 kJ·mol⁻¹ (liquid),
45.2 kJ·mol⁻¹ (gas)
Enthalpy of Vaporization (ΔfHvap): 32.73 kJ·mol⁻¹
Molecular Weight: 120.98 g/mol
XLogP3: 1.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0

Rotatable Bond Count: 1
Exact Mass: 119.95746 Da
Monoisotopic Mass: 119.95746 Da
Topological Polar Surface Area: 0 Å²
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 17.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular Formula / Molecular Weight: C₃H₅Br = 120.98
Physical State (20 °C): Liquid
Storage Temperature: Refrigerated (0–10 °C)

Store Under Inert Gas: Store under inert gas
Condition to Avoid: Light Sensitive, Air Sensitive, Heat Sensitive
CAS RN: 106‑95‑6
Reaxys Registry Number: 605308
PubChem Substance ID: 87563650
SDBS (AIST Spectral DB): 315
Merck Index (14): 288
MDL Number: MFCD00000244

FIRST AID MEASURES of 3-BROMO-PROPEN:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of 3-BROMO-PROPEN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of 3-BROMO-PROPEN:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of 3-BROMO-PROPEN:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of 3-BROMO-PROPEN:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of 3-BROMO-PROPEN:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available