4,4′-SULFONYLBISPHENOL

4,4′-Sulfonylbisphenol is a synthetic organic compound with the molecular formula C₁₂H₁₀O₄S, consisting of two hydroxyphenyl groups linked by a sulfone (–SO₂–) bridge, which gives it greater thermal and chemical stability compared to bisphenol A (BPA).
4,4′-Sulfonylbisphenol is widely used in the production of polycarbonate plastics, epoxy resins, polysulfones, and thermal paper coatings, and has gained importance as a BPA substitute in “BPA-free” consumer products such as bottles, packaging, and receipts.
Although marketed as a safer alternative, research indicates that 4,4′-Sulfonylbisphenol may also act as an endocrine disruptor, mimicking estrogen and raising concerns about its health and environmental impacts due to its persistence and widespread detection in water, soil, and humans.

CAS Number: 80-09-1
EC Number: 201-250-5
Molecular Formula: C12H10O4S
Molecular Weight: 250.27 g/mol

Synonyms: 4,4′-Sulfonyldiphenol, BPS, 4,4′-sulfonylbisphenol, Bis(4-hydroxyphenyl)sulfone, 4,4'-Sulfonyldiphenol, 80-09-1, Bisphenol S, Bis(4-hydroxyphenyl) sulfone, Phenol, 4,4'-sulfonylbis-, 4-(4-hydroxyphenyl)sulfonylphenol, 4,4'-Dihydroxydiphenyl sulfone, 4-Hydroxyphenyl sulfone, 4,4'-Sulfonylbisphenol, Bis(p-hydroxyphenyl) sulfone, Diphone C, Bis(4-hydroxyphenyl)sulfone, 4,4-Sulfonyldiphenol, Sulphonylbisphenol, 4,4'-Bisphenol S, 1,1'-Sulfonylbis(4-hydroxybenzene), Bis(p-hydroxyphenyl)sulfone, BPS 1, 4,4'-Sulphonyldiphenol, P,P'-Dihydroxydiphenyl sulfone, NSC 8712, PHENOL, 4,4'-SULFONYLDI-, BISPHENOL-S, CCRIS 2647, NSC 683541, EINECS 201-250-5, DHDPhS, BRN 2052954, 3OX4RR782R, DTXSID3022409, CHEBI:34372, AI3-08667, HSDB 8087, NSC-8712, NSC-683541, DTXCID602409, EC 201-250-5, 4-06-00-05809 (Beilstein Handbook Reference), EINECS 247-158-9, 1,1'-Sulfonylbis[4-hydroxybenzene], NSC 57909, BIS(4-HYDROXY(PHENYL))SULFONE, BIS(4-HYDROXY(PHENYL))SULPHONE, 1, 1'-SULFONYLBIS(4-HYDROXYBENZENE), 4,4'Bisphenol S, 4,4'Sulfonylbisphenol, 4,4'Sulphonyldiphenol, Phenol, 4,4'sulfonyldi, Bis(phydroxyphenyl)sulfone, bis(4hydroxyphenyl)sulfone, Phenol, 4,4'sulfonylbis, Bis(phydroxyphenyl) sulfone, bis(4hydroxyphenyl) sulfone, p,p'Dihydroxydiphenyl sulfone, 4,4'dihydroxydiphenyl sulfone, 1,1'Sulfonylbis(4hydroxybenzene), 247-158-9, 4-[(4-hydroxyphenyl)sulfonyl]phenol, MFCD00002350, 4,4'-dihydroxy diphenyl sulfone, NSC8712, 4-(4-hydroxyphenylsulfonyl)phenol, NSC683541, 25641-61-6, CAS-80-09-1, C12H10O4S, bisphenols, UNII-3OX4RR782R, 4,4'-dihydroxydiphenylsulfone, 4,4'-Dihydroxydiphenyl sulphone, 4-(4-hydroxybenzenesulfonyl)phenol, Phenol,4'-sulfonylbis-, 4,4'-sulfonyldiphenol, WLN: QR DSWR DQ, Bisphenol S (4,4'), ChemDiv3_000253, 4,4'-Sulfonylbis[phenol], Cambridge id 5137133, di-(4-Hydroxyphenyl)sulfone, Oprea1_709121, SCHEMBL18838, MLS001195068, BIDD:ER0209, bis(4-hydroxylphenyl) sulfone, SCHEMBL124022, 4,4'-Dihydroxydiphenylsulphone, 4,4'-dihydroxy diphenylsulfone, CHEMBL384441, SCHEMBL2038611, SCHEMBL8632609, 4,4'-Sulfonyldiphenol, 98%, 4,4'-Sulfonyldiphenol (4,4'-Dihydroxydiphenylsulfone), BP_06 (BPS), Bisphenol S, analytical standard, HMS2866C04, Tox21_201743, Tox21_302843, BBL004108, MSK000912, SBB056786, STK267009, AKOS000119535, CS-W012643, DS-5781, FB62571, HY-W011927, IDI1_019571, NCGC00164029-01, NCGC00164029-02, NCGC00256437-01, NCGC00259292-01, AC-11720, SMR000554491, B0495, EU-0066997, NS00010610, ST50308058, EN300-18083, E82999, AB00275288-05, Q418379, Z57158549, F0266-0794, Bisphenol S;4,4'-Dihydroxydiphenyl Sulfone;4,4'-Sulfonyldiphenol, 6JD, InChI=1/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14, Bis (4-hydroxyphenyl) sulfone, Bis (p-hydroxyphenyl) sulfone, 4,4-Bisphenol S, Bisphenol S, BPS 1 p,p-Dihydroxydiphenyl sulfone, 4-Hydroxyphenyl sulfone, Phenol, 4,4-sulfonylbis-, Phenol, 4,4-sulfonyldi-, SDP 1,1-Sulfonylbis (4-hydroxybenzene), Sulfonyl bisphenol, 4,4-Sulfonylbisphenol, 4,4-Sulfonyldiphenol, Phenol, 4,4'-sulfonylbis-, Bisphenol S, Diphone D, BPS-P, Diphone A, D 8, BPS-N, p,p'-Dihydroxydiphenyl sulfone, BS 3 (phenol), BS-PN, 1,1'-Sulfonylbis[4-hydroxybenzene], BPS-H, Ex 1B, 4,4'-Dihydroxydiphenyl sulfone, NSC 8712, Phenol, 4,4'-sulfonyldi- (6CI,8CI), Diphone C, 4,4'-Bisphenol S, BS 3, NSC 683541, Phenol, 4,4'-sulfonylbis-, Bis(p-hydroxyphenyl) sulfone, Dynamar FC 5166, 4-(4-Hydroxyphenylsulfonyl)phenol, Bis(4-hydroxyphenyl) sulfone, 4,4'-Sulfonylbis[phenol], 4-Hydroxyphenyl sulfone, Bisphenol S sulfonic acid ester, BPS 1, 4,4'-Sulfonyldiphenol, 4,4'-Sulphonyldiphenol, Bis(4-hydroxyphenyl)sulfone, 4,4-Dihydroxydiphenylsulfone, Bisphenol S, 4,4′‑sulfonylbisphenol, Bis(4‑hydroxyphenyl)sulfone, dioxydiphenylsulfone, BPS

4,4′-Sulfonylbisphenol is an organic compound with the molecular formula C₁₂H₁₀O₄S, belonging to the bisphenol family of synthetic phenolic compounds.
Structurally, 4,4′-Sulfonylbisphenol consists of two hydroxyphenyl groups linked by a sulfone (–SO₂–) bridge, which imparts greater thermal and chemical stability compared to its analogue bisphenol A (BPA).

4,4′-Sulfonylbisphenol typically appears as a white crystalline solid, soluble in organic solvents and moderately soluble in water.
4,4′-Sulfonylbisphenol is widely used in the production of polycarbonate plastics, epoxy resins, thermal paper coatings, and other polymeric materials, often marketed as a replacement for BPA in "BPA-free" products. 

However, scientific studies have shown that 4,4′-Sulfonylbisphenol can also exhibit endocrine-disrupting activity, mimicking estrogen and interfering with hormone signaling, raising concerns about its safety in food-contact materials, receipts, and consumer products.
Despite these concerns, 4,4′-Sulfonylbisphenol remains in use due to its high resistance to heat, light, and biological degradation, making it valuable in applications requiring long-lasting stability and durability.

4,4′-Sulfonylbisphenol is an organic compound with the formula (HOC6H4)2SO2.
4,4′-Sulfonylbisphenol has two phenol functional groups on either side of a sulfonyl group.
4,4′-Sulfonylbisphenol is commonly used in curing fast-drying epoxy resin adhesives.

4,4′-Sulfonylbisphenol is classified as a bisphenol, and a close molecular analog of bisphenol A (BPA).
4,4′-Sulfonylbisphenol differs from BPA in possessing a sulfone group (SO2) as the central linker in the molecule instead of the dimethylmethylene group (C(CH3)2) of bisphenol A.

4,4′-Sulfonylbisphenol is a sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
4,4′-Sulfonylbisphenol has a role as a metabolite and an endocrine disruptor.

4,4′-Sulfonylbisphenol is a sulfone and a bisphenol.
4,4′-Sulfonylbisphenol is functionally related to a diphenyl sulfone.

4,4′-Sulfonylbisphenol is part of the group of Other Bisphenols.
4,4′-Sulfonylbisphenol is part of the group of p,p'-Bisphenols.

4,4′-Sulfonylbisphenol, related to its chemical cousin Bisphenol A (BPA), is an organic compound used to make hard plastic and synthetic fibers.
4,4′-Sulfonylbisphenol is commonly used as a replacement for BPA in some types of paper receipts, can be used to lengthen color life in fabrics, and is a food packaging preservative.

4,4′-Sulfonylbisphenol is part of polyethersulfone (PES) plastic, which is used to make hard plastic items and synthetic fibers for clothing and other textiles.
4,4′-Sulfonylbisphenol is a chemical that some manufacturers are using as a replacement for Bisphenol A (BPA) due to its perceived lower potential for harm.

4,4′-Sulfonylbisphenol was developed as a safe substitution for BPA and is regulated by governments.
However, recent research suggests that 4,4′-Sulfonylbisphenol may be just as harmful as BPA.
Some manufacturers have opted for 4,4′-Sulfonylbisphenol as a substitute for BPA in their products.

4,4′-Sulfonylbisphenol is an organic compound that belongs to the class of bisphenols.
4,4′-Sulfonylbisphenol is structurally similar to Bisphenol A (BPA) but contains a sulfonyl group instead of the carbonyl group found in BPA.

4,4′-Sulfonylbisphenol is typically used as a substitute for BPA in the production of polycarbonate plastics and epoxy resins, particularly in applications where BPA's estrogenic activity is a concern.
4,4′-Sulfonylbisphenol is a white crystalline solid at room temperature and is soluble in organic solvents but has limited solubility in water.

4,4′-Sulfonylbisphenol exhibits similar thermal and chemical stability to BPA, making it suitable for various industrial applications.
However, concerns have been raised regarding its potential endocrine-disrupting properties, as 4,4′-Sulfonylbisphenol can mimic estrogen and may affect hormonal functions in living organisms.

As a result, 4,4′-Sulfonylbisphenol's use is being scrutinized, and research continues to evaluate its safety and environmental impact.
Overall, while 4,4′-Sulfonylbisphenol serves as a BPA alternative, its biological effects warrant careful consideration.

4,4′-Sulfonylbisphenol is a synthetic organic compound with the molecular formula C₁₂H₁₀O₄S, classified as a member of the bisphenol family of diphenylmethane derivatives.
4,4′-Sulfonylbisphenol's structure consists of two hydroxyphenyl rings connected by a central sulfone (–SO₂–) bridge, which distinguishes it from the more widely known bisphenol A (BPA), where the link is an isopropylidene group.

This sulfone linkage gives 4,4′-Sulfonylbisphenol higher thermal stability, oxidative resistance, and chemical durability, making it attractive for industrial use.
In its pure form, 4,4′-Sulfonylbisphenol appears as a white crystalline solid, with good solubility in organic solvents such as ethanol and acetone and moderate solubility in water.

4,4′-Sulfonylbisphenol has been used since the 1960s as a reactive monomer in the production of polycarbonate plastics, epoxy resins, phenolic resins, and polysulfones, and it is also employed in flame retardants, curing agents, and polymer additives.
One of 4,4′-Sulfonylbisphenol's most common modern applications is in thermal paper coatings, such as those used for receipts, tickets, and labels, where it acts as a color developer.
Following widespread restrictions on BPA due to its endocrine-disrupting properties, 4,4′-Sulfonylbisphenol gained commercial importance as a BPA substitute and is now frequently found in “BPA-free” consumer products including bottles, containers, medical devices, and packaging materials.

Despite being marketed as a safer alternative, toxicological studies suggest that 4,4′-Sulfonylbisphenol may also exhibit endocrine-disrupting activity, mimicking estrogen and interfering with normal hormone regulation in animals and humans.
Research indicates that 4,4′-Sulfonylbisphenol can affect reproductive, developmental, and metabolic processes, raising similar concerns to those associated with BPA.
Additionally, 4,4′-Sulfonylbisphenol is more environmentally persistent due to its resistance to biodegradation, leading to its detection in surface waters, sediments, and even human urine samples, signaling widespread exposure.

In industry, however, 4,4′-Sulfonylbisphenol is valued for its stability under heat, light, and chemical stress, which makes it suitable for high-performance applications where long-lasting durability is required.
4,4′-Sulfonylbisphenol is also less prone to leaching under certain conditions compared to BPA, though its environmental impact remains under evaluation.
Because of this balance between industrial utility and health concerns, 4,4′-Sulfonylbisphenol is considered both a critical industrial chemical and a compound of emerging concern in environmental and public health studies.

Market Overview of 4,4′-Sulfonylbisphenol:
The global market for 4,4′-Sulfonylbisphenol has grown significantly in recent decades, primarily as a response to increasing regulatory restrictions and consumer demand for alternatives to bisphenol A (BPA).
4,4′-Sulfonylbisphenol is widely marketed as a “BPA-free” substitute, particularly in consumer goods, packaging, and thermal papers, making it a key player in the bisphenol derivatives market.
4,4′-Sulfonylbisphenol's adoption has been strongest in industries where high thermal stability, oxidative resistance, and durability are required, such as plastics, epoxy resins, coatings, and specialty polymers.

A major driver of demand is the thermal paper industry, where 4,4′-Sulfonylbisphenol is used as a color developer in receipts, tickets, and labels.
As many countries restrict BPA in thermal papers, 4,4′-Sulfonylbisphenol has become the dominant replacement, accounting for a substantial share of global consumption.
Beyond paper, 4,4′-Sulfonylbisphenol is increasingly used in the production of polycarbonates, polysulfones, and epoxy resins for applications in electronics, automotive, construction, and consumer packaging.

Regionally, Asia-Pacific (especially China and Japan) dominates production and consumption due to 4,4′-Sulfonylbisphenol's large-scale chemical manufacturing and strong demand from packaging, electronics, and textile sectors.
North America and Europe represent significant markets as well, driven by regulatory shifts away from BPA but also tempered by rising public and scientific concerns over 4,4′-Sulfonylbisphenol’s own potential health risks.
Growing detection of 4,4′-Sulfonylbisphenol in the environment and in human biological samples has led to increased scrutiny, with some regulatory bodies considering restrictions similar to those applied to BPA.

Overall, the 4,4′-Sulfonylbisphenol market is characterized by steady but cautious growth: 4,4′-Sulfonylbisphenol benefits from its role as a critical industrial substitute for BPA, yet its long-term market trajectory will depend on regulatory developments, advances in safer alternatives, and increasing consumer awareness regarding potential endocrine-disrupting effects.

Uses of 4,4′-Sulfonylbisphenol:
4,4′-Sulfonylbisphenol is used across multiple industries as a reactive monomer, polymer additive, and functional substitute for bisphenol A (BPA).
4,4′-Sulfonylbisphenol's most prominent application is in thermal paper coatings (receipts, tickets, labels), where it serves as a color developer replacing BPA after regulatory bans, making up one of the largest global markets for 4,4′-Sulfonylbisphenol.

Beyond paper, 4,4′-Sulfonylbisphenol is a critical building block in the manufacture of polycarbonate plastics, epoxy resins, phenolic resins, and polysulfones, imparting high thermal and chemical stability to end products.
In the plastics and coatings industry, 4,4′-Sulfonylbisphenol is employed to enhance durability, hardness, and resistance to oxidation, which is especially valuable in automotive, electronics, and construction materials.

4,4′-Sulfonylbisphenol is also used in the formulation of flame retardants, curing agents, and stabilizers that improve the performance of high-strength polymers.
In consumer products, 4,4′-Sulfonylbisphenol is found in “BPA-free” goods such as food containers, water bottles, medical devices, and packaging films, where it acts as a replacement plasticizer or hardener.

In addition, 4,4′-Sulfonylbisphenol is incorporated into textiles, adhesives, and printing inks as a performance additive.
4,4′-Sulfonylbisphenol's sulfone bridge structure ensures long-term resistance to heat and UV degradation, which is why 4,4′-Sulfonylbisphenol is preferred in applications requiring durable, long-lasting performance under harsh conditions.

4,4′-Sulfonylbisphenol is used Monomer in polysulfone, polyethersulfone (PES), polycarbonate, epoxy, phenolic resins.
4,4′-Sulfonylbisphenol is used Thermal paper developer (e.g., receipts, tickets), paint/color fixer, leather tanning, plating dispersant, flame‑retardant resins.

4,4′-Sulfonylbisphenol is used Linker in fast-drying epoxy adhesives and anticorrosive coatings.
4,4′-Sulfonylbisphenol is used Transfer resistant to heat and light—analogous BPA substitute.

4,4′-Sulfonylbisphenol is a precursor to the polyethersulfone called Victrex.
4,4′-Sulfonylbisphenol is also used as an anticorrosive agent in epoxy glues.

4,4′-Sulfonylbisphenol may also be used to make colors last longer in some fabrics.
4,4′-Sulfonylbisphenol is a common replacement for BPA in some types of paper receipts, and is also in protective coatings inside some food cans.

4,4′-Sulfonylbisphenol is part of polyethersulfone (PES) plastic, which is used to make hard plastic items and synthetic fibers for clothing and other textiles.
4,4′-Sulfonylbisphenol may also be used to make colors last longer in some fabrics.
4,4′-Sulfonylbisphenol is a common replacement for BPA in some types of paper receipts, and is also in protective coatings inside some food cans.

Benefits of 4,4′-Sulfonylbisphenol:
4,4′-Sulfonylbisphenol offers several advantages that explain its widespread adoption as both an industrial material and a substitute for bisphenol A (BPA).
One of 4,4′-Sulfonylbisphenol's most significant benefits is its enhanced thermal and chemical stability; the presence of a sulfone (–SO₂–) bridge between its phenolic groups makes 4,4′-Sulfonylbisphenol more resistant to heat, light, and oxidative degradation than BPA.
This stability ensures that products containing 4,4′-Sulfonylbisphenol maintain their performance and structural integrity under demanding industrial conditions, such as in automotive parts, electronics, and high-performance coatings.

Another benefit is 4,4′-Sulfonylbisphenol's versatility as a reactive monomer and additive.
4,4′-Sulfonylbisphenol can be polymerized into polycarbonates, epoxy resins, polysulfones, and phenolic resins, producing plastics and coatings with high strength, transparency, and resistance to mechanical and environmental stress.
In the thermal paper industry, 4,4′-Sulfonylbisphenol functions effectively as a color developer, offering reliable print quality and durability, which is why it has become the dominant replacement for BPA in receipts and labels.

4,4′-Sulfonylbisphenol is also valued for its compatibility with existing production processes.
Manufacturers can substitute 4,4′-Sulfonylbisphenol for BPA in many formulations with minimal modifications, reducing transition costs while complying with BPA restrictions.
4,4′-Sulfonylbisphenol's ability to enhance hardness, flame resistance, and UV stability further extends its application in construction materials, adhesives, and consumer packaging.

From a regulatory perspective, 4,4′-Sulfonylbisphenol gained traction because it allowed companies to market products as “BPA-free”, meeting consumer demand for safer alternatives.
Although concerns about 4,4′-Sulfonylbisphenol’s own endocrine-disrupting potential are growing, its low volatility, durability, and broad functionality continue to make it a preferred choice in many industries.

Production and Use of 4,4′-Sulfonylbisphenol:
4,4′-Sulfonylbisphenol is the reaction product of two phenol molecules with one molecule of sulfuric acid.
2,4’-sulfonyldiphenol is often formed as a side product.
4,4′-Sulfonylbisphenol or its derivatives are used in the production of polyethersulfones, polysulfones, and epoxy resins, water-soluble and thermosetting resins, heat-sensitive developers, photographic chemicals, polyphthalate carbonates, polymer modifiers, and brominated flame retardants.

4,4′-Sulfonylbisphenol continuously finds application in synthetic polymers such as poly(ethylene terephthalate), poly(butylene terephthalate), polyurethanes, and epoxy resins.
In 2000, the Scientific Committee on Food (SCF) stated that 4,4′-Sulfonylbisphenol is used as comonomer for kitchen utensils, mainly for repeated use.
Polyethersulfone is one of the materials replacing bisphenol A (BPA)-based polycarbonate in baby bottles.

4,4′-Sulfonylbisphenol also substituted BPA in many thermal papers by now.
4,4′-Sulfonylbisphenol was found in high concentrations in receipts (up to 22 mg/g) and also detected in recycled food carton and food packaging paper, and in the lining of cans.

History of 4,4′-Sulfonylbisphenol:
4,4′-Sulfonylbisphenol was first synthesized in the early 20th century as part of broader research into phenolic compounds for use in plastics and resins.
Although bisphenol A (BPA) quickly became the dominant industrial bisphenol due to its cost-effectiveness and ease of large-scale production, 4,4′-Sulfonylbisphenol was recognized early on for its greater thermal and oxidative stability, derived from its sulfone bridge.

Initially, 4,4′-Sulfonylbisphenol found niche applications in high-performance polymers such as polysulfones and epoxy resins, where superior resistance to heat and chemicals was required.
However, 4,4′-Sulfonylbisphenol's large-scale industrial relevance began only in the late 20th and early 21st centuries, when concerns about BPA’s endocrine-disrupting properties led regulators, manufacturers, and consumers to seek alternatives.

By the 2000s, 4,4′-Sulfonylbisphenol had emerged as a prominent BPA substitute, especially in the thermal paper industry, where it was used as a developer for receipts, tickets, and labels after BPA was restricted or banned in many regions.
Around the same time, 4,4′-Sulfonylbisphenol began appearing in “BPA-free” consumer products, including water bottles, food containers, toys, and medical devices, marketed as safer alternatives despite limited toxicological research.
With growing regulatory pressure on BPA in the European Union, United States, Japan, and other markets, 4,4′-Sulfonylbisphenol gained commercial importance and became a mainstream component of the global bisphenol derivatives market.

In recent years, scientific studies have raised concerns that 4,4′-Sulfonylbisphenol, like BPA, may exhibit endocrine-disrupting activity, challenging the initial perception of it as a harmless substitute.
As a result, 4,4′-Sulfonylbisphenol is now regarded as both a critical industrial chemical and a compound of emerging regulatory concern, with ongoing research into its long-term effects on human health and the environment. 
Despite this scrutiny, 4,4′-Sulfonylbisphenol continues to play a major role in manufacturing due to its unique balance of stability, durability, and functional compatibility with existing polymer systems.

Handling and Storage of 4,4′-Sulfonylbisphenol:
Handle 4,4′-Sulfonylbisphenol in well-ventilated areas, avoiding inhalation of dust or direct contact with skin and eyes.
Use appropriate protective equipment including gloves, goggles, and lab coats. Eating, drinking, and smoking should be prohibited in work areas.

Store in tightly closed containers in a cool, dry, and well-ventilated place, away from heat sources, direct sunlight, and incompatible chemicals such as strong oxidizers.
Keep containers sealed to minimize dust formation.

Stability and Reactivity of 4,4′-Sulfonylbisphenol:
4,4′-Sulfonylbisphenol is stable under normal handling and storage conditions.
4,4′-Sulfonylbisphenol is resistant to hydrolysis and oxidation due to its sulfone bridge, but decomposition may occur at elevated temperatures, producing irritating fumes such as carbon oxides (CO, CO₂) and sulfur oxides (SOₓ).
4,4′-Sulfonylbisphenol should not be mixed with strong oxidizing agents or strong acids/bases, as these can trigger unwanted reactions.

First Aid Measures of 4,4′-Sulfonylbisphenol:

Inhalation:
Move the affected person to fresh air.
Seek medical attention if symptoms such as coughing or difficulty breathing occur.

Skin contact:
Wash thoroughly with soap and water.
Remove contaminated clothing.
Get medical advice if irritation develops.

Eye contact:
Rinse cautiously with water for at least 15 minutes.
Remove contact lenses if present and easy to do.
Seek immediate medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Do not induce vomiting unless directed by medical personnel.
Seek medical assistance promptly.

Firefighting Measures of 4,4′-Sulfonylbisphenol:
4,4′-Sulfonylbisphenol is not highly flammable but may burn under fire conditions.
Suitable extinguishing media include water spray, dry chemical, carbon dioxide (CO₂), or foam.

Firefighters should wear self-contained breathing apparatus (SCBA) and full protective gear.
Thermal decomposition or combustion may release toxic gases including carbon oxides and sulfur oxides.
Cool containers exposed to fire with water spray.

Accidental Release Measures of 4,4′-Sulfonylbisphenol:
Avoid raising dust during cleanup.
Evacuate non-essential personnel and ensure adequate ventilation.

Wear suitable personal protective equipment.
Sweep up or vacuum spilled material and place 4,4′-Sulfonylbisphenol in a suitable container for disposal.

Prevent release into drains or waterways.
Clean contaminated surfaces with water and detergent.
Dispose of waste according to local regulations.

Exposure Controls / Personal Protective Equipment of 4,4′-Sulfonylbisphenol:

Engineering Controls:
Use local exhaust ventilation or fume hoods to minimize dust exposure.

Respiratory Protection:
If ventilation is insufficient, wear an approved respirator suitable for dust.

Skin Protection:
Wear chemical-resistant gloves (nitrile, neoprene) and protective clothing.

Eye Protection:
Use safety goggles or face shields.

Hygiene Measures:
Wash hands, face, and exposed skin thoroughly after handling.
Avoid eating, drinking, or smoking during use.

Identifiers of 4,4′-Sulfonylbisphenol:
Abbreviation: BPS
CAS Number: 80-09-1
EC Number (EINECS): 201-250-5
PubChem CID: 6626
ChemSpider ID: 6382
ChEBI ID: 5253
UNII (FDA): 1N03ZK8642
Beilstein Registry Number: 1854456
Merck Index: 14, 1361

Molecular Formula: C₁₂H₁₀O₄S
Molecular Weight: 250.27 g/mol
Exact Mass: 250.030 g/mol
Elemental Composition: C (57.6%), H (4.0%), O (25.6%), S (12.8%)

InChI: InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H
InChI Key: AOAHWZROJZQKDW-UHFFFAOYSA-N
Canonical SMILES: C1=CC(=CC=C1O)S(=O)(=O)C2=CC=C(C=C2)O
Isomeric SMILES: OC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)O

Formula: C₁₂H₁₀O₄S
InChI: InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H
InChI Key: VPWNQTHUCYMVMZ-UHFFFAOYSA-N
SMILES: O=S(=O)(C1=CC=C(O)C=C1)C2=CC=C(O)C=C2
CAS number: 80‑09‑1
EC (EINECS) number: 201‑250‑5
PubChem CID: 6626
ChemSpider ID: 6374
IUPAC name: 4,4′‑Sulfonyldiphenol
Chemical formula: C₁₂H₁₀O₄S; Molar mass: ~250.27g/mol

Properties of 4,4′-Sulfonylbisphenol:
Chemical formula: C₁₂H₁₀O₄S
Molar mass: 250.27 g·mol⁻¹
Appearance: White colorless solid; forms needle shaped crystals in water
Density: 1.3663 g/cm³
Melting point: 245 to 250 °C (473 to 482 °F; 518 to 523 K)
Solubility in water: 1100 mg/L
Solubility: Soluble in ethanol

Molecular Weight: 250.27 g/mol
XLogP3: 1.9
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 250.02997997 Da
Monoisotopic Mass: 250.02997997 Da
Topological Polar Surface Area: 83 Ų
Heavy Atom Count: 17
Complexity: 302
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting Point: 215–247°C
Molecular weight: 250.28
Solubility: alcohol, acetone, ether, alkali
Linear Formula: O₂S(C₆H₄OH)₂
CAS Number: 80-09-1
Molecular Weight: 250.27
Beilstein: 2052954
EC Number: 201-250-5
MDL number: MFCD00002350
UNSPSC Code: 85151701

Density: 1.43 g/cm³
Oxidizing properties: None
Other safety information
Dissociation constant: 8 at 22°C
Molecular form: C₁₂H₁₀O₄S

Appearance: NA
Mol. Weight: 250.27
Storage: 2–8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA
Formula: C₁₂H₁₀O₄S
CAS No.: 80‑09‑1
EC No.: 201‑250‑5