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Benzyl cyanide is belongs to the class of organic compounds known as benzyl cyanides.
These are organic compounds containing an acetonitrile with one hydrogen replaced by a phenyl group.
Benzyl cyanide is found, on average, in the highest concentration within kohlrabis and peppermints.
Benzyl cyanide has also been detected, but not quantified, in several different foods, such as cabbages, cauliflowers, garden and cherry tomato.
CAS Number: 140-29-4
EC Number: 205-410-5
IUPAC Name: Phenylacetonitrile
Chemical Formula: C8H7N
Other names: Benzeneacetonitrile, 2-Benzyl cyanide, BENZYL CYANIDE, 140-29-4, Benzyl cyanide, alpha-Tolunitrile, alpha-Cyanotoluene, (Cyanomethyl)benzene, Phenyl acetyl nitrile, benzylcyanide, Benzylnitrile, Acetonitrile, phenyl-, Benzylkyanid, USAF KF-21, Phenyl-acetonitrile, Acetic acid, phenyl-nitrile, 2-phenylethanenitrile, .omega.-Cyanotoluene, Phenacetonitrile, Benzyl cyanide, liquid, omega-Cyanotoluene, .alpha.-Tolunitrile, NSC 118418, UNII-23G40PRP93, .alpha.-Cyanotoluene, 2-phenyl-acetonitrile, Toluene, .alpha.-cyano-, 23G40PRP93, MFCD00001894, WLN: NC1R, Benzylkyanid [Czech], Toluene, alpha-cyano-, CCRIS 4698, HSDB 2103, EINECS 205-410-5, UN2470, enzylcyanide, phenylacetonitile, AI3-04975, phenylacteonitrile, Cyanophenylmethane, alpha -cyano-, alpha -tolunitrile, phenyl acetonitrile, BnCN, alpha -cyanotoluene, benzene acetonitrile, benzene-acetonitrile, alpha-Cyano-Toluene, Ethyl2-Fluoroacrylate, 286425-40-9, A-TOLUNITRILE, N#C[C]c1ccccc1, alpha-Benzyl cyanide, Benzyl cyanide, 98%, PubChem20468, Toluene, alpha -cyano-, Benzeneacetonitrile, 9CI, Benzyl cyanide-[13C2], ACMC-1C0PN, DEA Code 8735, DSSTox_CID_1492, Milnacipran EP Impurity E, benzyl cyanide, >=99%, EC 205-410-5, Benzyl cyanide, liquid [UN2470] [Poison], DSSTox_RID_76184, DSSTox_GSID_21492, SCHEMBL37831, laquo Omegaraquo -cyanotoluene, CHEMBL3560735, DTXSID2021492, CHEBI:25979, NSC3407, OTAVA-BB 1519434, Benzyl cyanide, analytical standard, NSC-3407, Benzyl cyanide (Benzyl Cyanide), ZINC1666748, Tox21_200217, ANW-20559, LABOTEST-BB LT00891699, NSC118418, SBB058386, STL199233, AKOS000118943, AS01366, MCULE-3500109780, NSC-118418, UN 2470, NCGC00090854-01, NCGC00090854-02, NCGC00257771-01, CAS-140-29-4, DB-004016, BB 0304017, FT-0657342, P0128, ST51017243, C16074, Benzyl cyanide, liquid [UN2470] [Poison], A807640, Q425620, J-519675, Z57131036, F0001-0481, Benzyl cyanide; (Cyanomethyl)benzene; 2-Benzyl cyanide; 2-Phenylethanenitrile; Benzeneethanenitrile; Benzyl cyanide
Benzyl cyanide has the chemical formula C6H5CH2CN.
Benzyl cyanide is considered as the aromatic liquid chemical compound type.
Benzyl cyanide has the molar mass of 117.15 g/mol and density of 1.015 g/cm3 .
The melting point of benzyl cyanide is −24 °C or 249 K.
While the boiling point of this compound is 233 to 234 °C or 506 to 507 K.
The characteristic of Benzyl cyanide is colorless, toxic content and oily form.
In the chemical reaction, benzyl cyanide can be used in the hydrolysis reaction and pinner reaction.
In the hydrolysis reaction, benzyl cyanide can yield phenylacetic acid.
While using the pinner reaction, benzyl cyanide is able to produce phenylacetic acid esters.
The benzyl cyanide compound can also form an active methylene unit on the carbon between the aromatic ring and the nitrilefunctional group.
The active carbon named nitrile anion is a great reactive intermediate in the making of new carbon carbon bonds.
Benzyl cyanide is a colorless oily aromatic liquid and an important precursor to numerous compounds in organic chemistry.
Benzyl cyanide is a useful precursor to numerous drugs with recreational use potential.
Benzyl cyanide can be produced via Kolbe nitrile synthesis between benzyl chloride and sodium cyanide and by oxidative decarboxylation of phenylalanine.
Hydrolysis of benzyl cyanide gives phenylacetic acid.
Sulfuric acid is often used as catalyst, usually as 70% concentration.
Benzyl cyanide is a colorless liquid, immiscible with water, but miscible with other organic solvents.
Benzyl Cyanide, C6H5CH2CN, is used in organic synthesis for dyes, perfumes, pesticides, and pharmaceuticals, especially penicillin precursors.
Benzyl cyanide is used in organic synthesis; as a chemical intermediate for pharmaceutical drugs; with esters for perfumes and flavors; in the synthesis of optical bleaches for fibers; in the production of insecticides
Benzyl Cyanide is colorless to pale yellow, oily, aromatic liquid organic compound that is produced by the reaction of benzyl chloride with sodium cyanide.
Benzyl cyanide (abbreviated BnCN) is an organic compound with the chemical formula C6H5CH2CN.
Benzyl cyanide is an important precursor to numerous compounds in organic chemistry.
Benzyl cyanide can be produced via Kolbe nitrile synthesis between benzyl chloride and sodium cyanide and by oxidative decarboxylation of phenylalanine.
Benzyl cyanides can also be prepared by arylation of silyl-substituted acetonitrile.
Benzyl cyanide undergoes many reactions characteristic of nitriles.
Benzyl cyanide can be hydrolyzed to give phenylacetic acid or it can be used in the Pinner reaction to yield phenylacetic acid esters.
Hydrogenation gives β-phenethylamine.
Benzyl cyanide contains an "active methylene unit".
Bromination occurs gives PhCHBrCN.
A variety of base-induced reactions result in the formation of new carbon-carbon bonds.
Benzyl cyanide is used as a solvent and as a starting material in the synthesis of fungicides, fragrances (phenethyl alcohol), antibiotics, and other pharmaceuticals.
The partial hydrolysis of BnCN results in 2-phenylacetamide, a known anticonvulsant.
Benzyl cyanide is synthesized by reaction of benzyl chloride with potassium cyanide or sodium cyanide .
The nitrile is a natural constituent of plants and is a constituent of foods, particularly citrus fruits, papaya, cabbage, mushrooms, roasted onions, tomatoes, cocoa, tea, roasted peanuts and cauliflower .
The benzyl cyanide, at least in part, is formed by breakdown of benzylglucosinolate in the plant material.
Benzeneacetonitrile, also known as alpha-cyanotoluene or alpha-tolunitrile, belongs to the class of organic compounds known as benzyl cyanides.
These are organic compounds containing an acetonitrile with one hydrogen replaced by a phenyl group.
Benzeneacetonitrile exists in all living organisms, ranging from bacteria to humans.
Benzeneacetonitrile is found, on average, in the highest concentration within kohlrabis and peppermints (Mentha X piperita).
Benzeneacetonitrile has also been detected, but not quantified in, several different foods, such as garden tomato, blackberries, garden tomatoes, cherry tomatoes, and cauliflowers.
This could make benzeneacetonitrile a potential biomarker for the consumption of these foods.
Benzeneacetonitrile is a secondary metabolite.
Secondary metabolites are metabolically or physiologically non-essential metabolites that may serve a role as defense or signalling molecules.
In some cases they are simply molecules that arise from the incomplete metabolism of other secondary metabolites.
Based on a literature review a significant number of articles have been published on Benzeneacetonitrile.
Benzyl cyanide is used in organic synthesis for dyes, perfumes, pesticides, pharmaceuticals, especially penicillin precursors.
Benzyl cyanide is a nitrile that is acetonitrile where one of the methyl hydrogens is substituted by a phenyl group.
Benzyl cyanide has a role as a pheromone and an animal metabolite.
Benzyl cyanide is a nitrile and a member of benzenes.
Benzyl cyanide derives from an acetonitrile.
Physical Description:
Benzyl cyanide, liquid appears as a colorless oily liquid with an aromatic odor.
Insoluble in water and slightly denser than water.
Used to make other chemicals.
USES:
Benzyl cyanide is employed as a chemical intermediate for the synthesis of amphetamine, phenobarbital and methyl phenidylacetate.
Benzyl cyanide is also used for perfumes and flavors and is, therefore, added to soaps, detergents, creams and lotions.
Benzyl cyanide is used in organic synthesis, especially of penicillin precursors.
Benzyl cyanide is used as a chemical intermediate for amphetamines, phenobarbital; the stimulant, methyl phenidylacetate; esters as perfumes and flavors.
Benzyl Cyanide, C6H5CH2CN, is used in organic synthesis for dyes, perfumes, pesticides, and pharmaceuticals, especially penicillin precursors.
Benzyl Cyanide is an important intermediate for a variety of useful, and sometimes dangerous, compounds.
Benzyl cyanide is used in the production of phenobarbital, methylphenidate, and other amphetamines.
Benzyl cyanide is also used to make methadone, pethidine, and ketobemidone if further substituted.
In organic synthesis, benzyl chloride is used for the introduction of the benzyl protecting group for alcohols, yielding the corresponding benzyl ether, and carboxylic acids, yielding the corresponding benzyl ester.
Benzyl Cyanide or BnCN is the type of organic compound which is made by the reaction of benzyl chloride and sodium cyanide.
Benzyl cyanide has the chemical formula C6H5CH2CN.
This compound is toxic, colorless (sometimes pale yellow) and oily.
Benzyl cyanide is also included in the aromatic liquid compound category.
The main use of benzyl cyanide is as precursor to varied compounds, both useful compound in organic chemistry.
You can see benzyl uses in some fields including production of chemicals like phenobarbital, methylphenidate, and some other amphetamines.
Aside from its uses in certain chemical production, benzyl cyanide is also useful for other applications like organic synthesis of dyes, perfume, pesticides and pharmaceuticals.
You can find the important uses of benzyl cyanide in as the penicillin precursors.
The popular uses of this colorless compound is for the making of methylphenidate, phenobarbital, and other amphetamines.
Benzyl cyanide can be used as the starting material and as solvent in the fungicides’ synthesis process, antibiotics and some pharmaceutical purposes.
Benzyl cyanide is also important in fragrances production which is used to produce phenethyl alcohol.
The partial hydrolysis reaction of benzyl cyanide can make the anticonvulsant ot 2-phenylacetamide.
In the pharmaceutical industries, benzyl cyanide has the broad uses as a precursor for some popular pharmaceutical products.
Some of the benzyl cyanide uses in the pharmaceutical field are as follow:
In Anorectics, as an example in production of sibutramine
In production of analgesics, including ethoheptazine, ketobemidone, pethidine, and phenoperidine
In making of Antiarrhythmics like disopyramide and others
In the Antidepressants production
In production of Antihistamines, such as levocabastine and chlorphenamine
Used in the production of antimalarial medications, like pyrimethamine
For antitussives such as isoaminile, oxeladin, butethamate, pentapiperide, pentoxyverine and some more
For Diuretics, like triamterene
For Hypnotics cure like alonimid and phenobarbital
For production of Spasmolytics, including pentapiperide and drofenine
For stimulants like methylphenidate
For Azatadine production
Extraction solvent for fatty acids, oils and unsaturated hydrocarbons
Solvent for spinning and casting and extractive distillation based on its selective miscibility with organic compounds.
Removing agent of colouring matters and aromatic alcohols
Non-aqueous solvent for titrations and for inorganic salts
Recrystallization of steroids
Parent compound for organic synthesis
Solvent or chemical intermediate in biochemistry ( pesticide sequencing and DNA synthesis)
High-pressure liquid chromatographic analysis
Catalyst and component of transition-metal complex catalysts
Stabilizer for chlorinated solvents
Chemical intermediate and solvent for perfumes and pharmaceuticals
