BLACK COHOSH EXTRACT

Black Cohosh extract comes from the roots of the black cohosh plant (Actaea racemosa), also known as Cimicifuga racemosa. 
Black Cohosh extract has been used traditionally in herbal medicine, especially for women's health issues.
Black Cohosh extract, a member of the buttercup family, is a perennial plant native to North America. 

CAS Number: 84776-26-1
Molecular Formula: C5H10O5
Molecular Weight: 150.1299
EINECS Number: 283-951-6

Synonyms: 84776-26-1, BLACK COHOSH, POWDERED BLACK COHOSH EXTRACT (1.5 G);blackcohoshextract,snakerootextract;Actaea racemosa;Bugbane, black;Cimicifuga;Cohosh, black;Blach Cohosh Extract;Triterpenoid Saponins

Black Cohosh extract is a woodland herb native to North America. 
The root is used as medicine and is often used for estrogen-related conditions.
In some parts of the body, black cohosh might increase the effects of estrogen. 

Other, mostly historical, names for this herb include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. 
Black Cohosh extract has a long history of use. Native Americans used it, for example, to treat musculoskeletal pain, fever, cough, pneumonia, sluggish labor, and menstrual irregularities. 
European settlers used black cohosh as a tonic to support women’s reproductive health.

In other parts of the body, black cohosh might decrease the effects of estrogen. 
Black Cohosh extract should not be thought of as an "herbal estrogen" or a substitute for estrogen.
People commonly use Black Cohosh extract for symptoms of menopause, premenstrual syndrome (PMS), painful menstruation, weak and brittle bones, and many other conditions, there is no good scientific evidence to support most of these uses.

Black Cohosh extract, a member of the buttercup family, grows in North America. 
Native Americans traditionally used black cohosh for a variety of ailments and introduced it to European colonists.
Currently, Black Cohosh extract is promoted as a dietary supplement for hot flashes and other menopausal symptoms. 

Black Cohosh extract’s also been promoted for other conditions, including menstrual cramps and premenstrual syndrome, and to induce labor.
The part of the black cohosh plant used in herbal preparations is the root or rhizome (underground stem).
Black Cohosh extract has been studied for menopause symptoms in people. 

Most of the older studies were not of the highest quality. 
More recent studies have been of higher quality, but they have differed in the formulation, plant species, or dose used, so it’s difficult to know the herb’s effects with any certainty. 
Black Cohosh extract has not been studied as much for conditions other than menopause.

For centuries, the roots of the North American black cohosh plant have been used for various ailments. 
Black Cohosh extract is now a popular remedy for the symptoms of menopause. 
This has been especially true since the risks of a standard treatment for menopause hormone therapy were publicized more than a decade ago.

If menopause has all hot and bothered, may have heard that taking black cohosh can help reduce vasomotor symptoms (more commonly known as hot flashes and night sweats). 
This herbal supplement has been used since ancient times, but only recently has it come to be known as a possible combatant of this common and uncomfortable symptom of menopause.
Black Cohosh extract, a member of the buttercup family, is a perennial plant which native to North America. 

Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. 
Black Cohosh extract has a long history of use. 
Native Americans used Black Cohosh extract for its purported benefits in treating musculoskeletal pain, fever, cough, pneumonia, sluggish labor, and menstrual irregularities. 

European settlers were said to use Black Cohosh extract as a tonic to support female reproductive health.
Hormone replacement therapy (HRT) is the standard treatment for early symptoms in post-menopausal women, however, increases the risk of stroke, heart diseases, as well as breast cancer in older women. Various studies have shown that the number of post-menopausal women using hormone replacement therapy is currently low and that the effects of hormone replacement therapy in reducing menopausal symptoms are not as positive as expected. 

For these reasons, there has been a trend toward using alternative therapies to relieve menopausal symptoms.
Black Cohosh extract has been associated with serious safety concerns.
Results from studies suggest that C. racemosa possesses a central activity instead of a hormonal effect.

The American College of Obstetrics and Gynecology guidelines on the use of botanicals, such as Black Cohosh extract, for the management of menopausal symptoms the use of for up to six months, especially in treating the symptoms of sleep and mood disturbance, and hot flushes.
Black Cohosh extract is provided as delivered and specified by the issuing Pharmacopoeia. 
All information provided in support of Black Cohosh extract, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.
These are believed to have estrogenic effects and may influence hormonal activity.
Phytoestrogens that can mimic estrogen in the body.

Contribute to the plant’s anti-inflammatory and antioxidant properties.
Compounds that may have various physiological effects.
Black Cohosh extract is commonly used to alleviate hot flashes and night sweats associated with menopause.

May help reduce mood swings, irritability, and other emotional symptoms related to menopause.
Can help manage symptoms of vaginal dryness by supporting hormonal balance.
Used to ease symptoms of PMS, including cramps, mood swings, and irritability.

May help regulate menstrual cycles and alleviate symptoms of menstrual discomfort.
Some studies suggest black cohosh might have benefits for bone health and help prevent osteoporosis, particularly in postmenopausal women.
Black Cohosh extract may help with symptoms of arthritis due to its anti-inflammatory properties.

Sometimes used for relief from muscle and joint pain.
There is some evidence that black cohosh may have a mild effect on lowering blood pressure.
Black Cohosh extracts potential calming effects might help with stress and anxiety, although evidence is limited.

Standardized extracts in pill form, typically containing 20-40 mg of black cohosh per dose.
Liquid extracts that can be taken directly or mixed with water.
Herbal teas made from black cohosh root.

Dosages can vary based on the specific product and concentration. 
Commonly, doses range from 20-40 mg of standardized extract daily, often divided into two or three doses. 
Always follow the product’s dosage instructions or a healthcare provider’s advice.

May cause dizziness or lightheadedness in some individuals.
Rarely, some individuals might experience skin rash or itching.
Black Cohosh extract may have estrogen-like effects, which could be problematic for individuals with hormone-sensitive conditions such as breast cancer or endometriosis.

Not recommended during pregnancy due to potential hormonal effects and lack of safety data.
Limited information on safety during breastfeeding; consult a healthcare provider before use.
May interact with medications that affect hormonal balance, such as birth control pills or hormone replacement therapy.

Potential interactions with anticoagulants or antiplatelet medications.
Rare cases of liver toxicity have been reported with black cohosh use. 
Individuals with liver conditions should use it cautiously and consult a healthcare provider.

Always consult with a healthcare provider before starting black cohosh, especially if have underlying health conditions, are pregnant or breastfeeding, or are taking other medications.
Pay attention to how your body responds to black cohosh and discontinue use if any adverse effects occur.
Ensure the black cohosh supplement is from a reputable manufacturer and is standardized for quality and efficacy.

Black Cohosh extract may help balance hormones and regulate the menstrual cycle, especially in cases of irregular periods or amenorrhea (absence of menstruation).
Some women use black cohosh to help alleviate pain and other symptoms associated with endometriosis, although evidence is limited and more research is needed.
Black Cohosh extract may be used to help manage symptoms associated with uterine fibroids, such as heavy bleeding or pelvic pain.

There is some evidence suggesting that Black Cohosh extract might help improve sleep quality and reduce insomnia related to menopause.
Some studies suggest that Black Cohosh extract might have immune-modulating effects, potentially supporting overall immune function.
Research indicates that black cohosh can be effective in reducing hot flashes and other menopausal symptoms, though results vary between studies. 

Some clinical trials show significant improvement, while others show minimal effects.
Black Cohosh extract studies comparing black cohosh to HRT suggest that while black cohosh may offer some symptom relief, it generally does not have the same level of effectiveness as HRT for severe symptoms.
Black Cohosh extract’s effects are believed to be related to its estrogen-like activity, which may influence estrogen receptors and hormone pathways, though the exact mechanisms are not fully understood.

Most studies focus on short-term use. Long-term safety data is limited, so it is advisable to use black cohosh under medical supervision if taken for extended periods.
The quality and potency of black cohosh supplements can vary significantly. 
Standardized extracts that contain specific concentrations of active ingredients are generally preferred to ensure consistent effects.

There have been isolated reports of liver damage associated with black cohosh use, though such cases are rare. 
Individuals with liver disease or those taking medications that affect the liver should exercise caution.
Allergic reactions to black cohosh are uncommon but possible. 

Black Cohosh extract may interact with other herbal supplements that affect hormonal balance, such as dong quai or ginseng. 
Be cautious when combining supplements and consult a healthcare provider.
Due to its estrogenic effects, black cohosh should be used cautiously or avoided by individuals with hormone-sensitive conditions, such as breast cancer or endometrial cancer.

There is some evidence suggesting potential interactions with antidepressant medications. 
Consult a healthcare provider if are on such medications.
Black Cohosh extract is important to adhere to recommended dosages and avoid exceeding the suggested amount to reduce the risk of adverse effects.

Uses Of Black Cohosh extract:
Black Cohosh extract helps reduce the frequency and intensity of hot flashes experienced during menopause.
Alleviates night sweats, which can disrupt sleep.
May help stabilize mood and reduce irritability associated with menopause.

Black Cohosh extract addresses symptoms of vaginal dryness and discomfort.
Black Cohosh extract is used to alleviate PMS symptoms such as cramps, bloating, and mood swings.
Can help manage irregular menstrual cycles and ease menstrual discomfort.

Some studies suggest that black cohosh may help maintain bone density and reduce the risk of osteoporosis, especially in postmenopausal women.
May help with symptoms of arthritis and other inflammatory conditions due to its anti-inflammatory properties.
Potential mild effects on lowering blood pressure, though evidence is limited.

May help with stress and anxiety due to its calming properties, although research is less conclusive in this area.
Potential immune-modulating effects that could support overall immune function.
Sometimes used to manage symptoms associated with uterine fibroids and endometriosis, such as pelvic pain and heavy bleeding.

Black Cohosh extract may help improve sleep quality and reduce insomnia related to menopausal symptoms.
Commonly available as standardized extracts in pill form.
Liquid extracts that can be taken directly or mixed with water.

Black Cohosh extract herbal teas made from black cohosh root.
Commonly dosed between 20-40 mg per day, often divided into two or three doses.
Always follow the product’s dosage instructions or the advice of a healthcare provider.

Black Cohosh extract may help relieve menstrual cramps and dysmenorrhea (painful menstruation) by reducing muscle contractions and inflammation in the pelvic area.
Black Cohosh extract can be used to alleviate pelvic pain not only from menstruation but also from conditions like pelvic inflammatory disease or chronic pelvic pain.
Some women use black cohosh to help manage joint pain associated with menopause. 

Its anti-inflammatory properties may provide symptomatic relief.
May be used to support uterine health and function, potentially benefiting conditions like uterine fibroids or endometrial hyperplasia, though evidence is not conclusive.
There is some evidence suggesting black cohosh may support thyroid function, particularly in the context of hormonal balance, though more research is needed in this area.

Research comparing Black Cohosh extract to HRT shows mixed results. While black cohosh can be effective for some symptoms, it may not provide the same level of relief as HRT for severe menopausal symptoms.
Black Cohosh extract is believed to act on estrogen receptors in the body, though its effects are less well-understood compared to other phytoestrogens. 
Black Cohosh extract may have a selective estrogenic effect, influencing some estrogen receptors while not affecting others.

Most studies focus on short-term use, and long-term safety data is limited. 
Ongoing research aims to better understand the long-term effects and potential risks of prolonged Black Cohosh extract use.
Black Cohosh extract is sometimes used in combination with other herbal remedies, such as red clover or dong quai, to enhance its effects on menopausal symptoms. 

However, the efficacy and safety of these combinations require more research.
Black Cohosh extract may help manage symptoms during perimenopause, the transition phase before menopause, by stabilizing hormone levels and reducing symptoms like irregular periods and mood swings.
Black Cohosh extract might interact with or affect the efficacy of these treatments.

Individuals with liver conditions or those taking medications that affect liver function should monitor liver health regularly while using black cohosh.
Black Cohosh extract have a history of allergies to herbal supplements or plants, consider doing a patch test or consulting with a healthcare provider before using black cohosh.
Always consult with a healthcare provider to determine if black cohosh is appropriate for your specific health needs and to establish the right dosage and duration of use.

Safety Profile Of Black Cohosh extract:
Black Cohosh extract some users may experience nausea or an upset stomach.
Can cause bloating, cramping, or general abdominal discomfort.
Headaches are a reported side effect, which may occur in some individuals.

Some people may experience dizziness or lightheadedness.
Black Cohosh extract rarely, users may develop a rash, itching, or hives.
In very rare cases, severe allergic reactions can occur, including swelling or difficulty breathing. 

Due to its estrogen-like effects, black cohosh should be used cautiously by individuals with hormone-sensitive conditions such as breast cancer, endometrial cancer, or other estrogen-related cancers.
Prolonged use might disrupt hormonal balance, especially in those with existing hormonal issues.
There have been rare reports of liver damage or hepatotoxicity associated with black cohosh use. 

Individuals with liver conditions or those taking medications that affect liver function should use it with caution.
Black Cohosh extract those using black cohosh long-term should have regular liver function tests to monitor for potential liver issues.