BORANE-TRIETHYLAMINE

Borane-Triethylamine is a stable, colorless, and highly reactive complex composed of borane (BH₃) coordinated with triethylamine (NEt₃).
Borane-Triethylamine is widely used as a reducing agent in organic synthesis, particularly for hydroboration and selective reduction reactions.
Borane-Triethylamine offers improved handling and storage stability compared to borane gas or other borane complexes, making it safer and more convenient in laboratory and industrial settings.

CAS Number: 13385-18-5
EC Number: 236-118-2
Molecular Formula: C6H18BN
Molecular Weight: 115.02 g/mol

Synonyms: Triethylamine-Borane Complex, Borane Triethylamine Complex, Borane–NEt₃, Borane–TEA, Triethylamine Borane Adduct, BH3·NEt3, Triethylborane Amine Complex, BH₃–Et₃N, Triethylamine Complex of Borane, Organoborane Reducing Agent, Borane–Triethylamine, Triethylamine Borane, TEA‑Borane, TEAB, Borane‑Triethylamine Complex, Triethylamine–Borane, Triethylamine Borane Complex, Borane‐Triethylethanamine, (C₂H₅)₃N·BH₃, Aminoborane, Amine‑Borane Adduct, Boron Hydride Adduct, N‑Triethyl Borazane, Trimethylamine Borane analog, Triethylamide Borane, Borazane Triethylamine Complex, Triethylamine Boron Trihydride, Amine–Borane Stabilized Borane, Lewis Base Borane, Borane Lewis Adduct, BH₃·NEt₃, 1:1 Borane–Triethylamine, Triethylamine–Boron Hydride, NSC 59740, CAS 1722‑26‑5, EC 217‑022‑3, PubChem CID 6330188, UNII WEA26VJ71E, RTECS ?), C₆H₁₈BN, MFCD00012423, Amine Borane TEAB reagent, Reagent‑Grade TEAB, Analytical‑Grade Borane–Triethylamine, ≥95 % Triethylamine Borane, ≥97 % Triethylamine Borane

APPLICATIONS

Borane-Triethylamine is used as a selective reducing agent in organic chemistry to reduce aldehydes, ketones, and acid chlorides to alcohols.
Borane-Triethylamine is employed in hydroboration reactions, where it adds across double and triple bonds in alkenes and alkynes.
Borane-Triethylamine is used for the preparation of boronic esters and other boron-containing intermediates.

Borane-Triethylamine is a key reagent in the synthesis of pharmaceuticals and agrochemicals.
Borane-Triethylamine enables chemoselective reduction steps that are essential for complex molecule construction.
Borane-Triethylamine is included in multi-step synthetic pathways due to its mild reducing power and compatibility with other functional groups.

Borane-Triethylamine is used in peptide synthesis for the reduction of N-protected amino acids or peptide intermediates.
Borane-Triethylamine helps avoid racemization and is valued for its selectivity in reducing sensitive compounds.
Borane-Triethylamine is applied in the synthesis of amino alcohols and related compounds.

Borane-Triethylamine is employed in the polymer industry as a chain transfer or modifying agent in radical polymerizations.
Borane-Triethylamine modifies the molecular weight and branching structure of synthetic polymers.
Borane-Triethylamine enables production of polymers with tailored properties for adhesives and coatings.

Borane-Triethylamine is used in academic and industrial laboratories for reductive amination reactions.
Borane-Triethylamine facilitates the conversion of imines and oximes to corresponding amines with high selectivity.
Borane-Triethylamine is preferred in synthesis protocols that require mild reaction conditions and high yields.

Borane-Triethylamine is involved in the production of specialty boranes and borohydrides.
Borane-Triethylamine is used as a precursor to other organoborane compounds via substitution or transmetallation reactions.
Borane-Triethylamine provides a controlled source of borane for custom reagent development.

Borane-Triethylamine is studied in materials science for its role in forming boron-doped materials and ceramics.
Borane-Triethylamine contributes to the development of boron-based electronic materials.
Borane-Triethylamine is investigated in nanomaterials synthesis for its reductive and boron-donating properties.

Borane-Triethylamine is used in the fragrance and flavor industry to reduce aldehydes in aroma compound synthesis.
Borane-Triethylamine contributes to cleaner, milder synthetic routes for olfactory compounds.
Borane-Triethylamine is chosen when hydrogenation is not suitable due to sensitive groups.

Borane-Triethylamine is used in fuel chemistry for hydrogen storage and boron hydride fuel components.
Borane-Triethylamine provides a compact hydrogen source in specialized propulsion or fuel systems.
Borane-Triethylamine research supports innovation in alternative energy and energy-dense fuels.

Borane-Triethylamine is widely used as a reducing agent in organic synthesis.
Borane-Triethylamine is employed in the reduction of carboxylic acids to primary alcohols.
Borane-Triethylamine is effective in reducing esters and lactones under mild conditions.

Borane-Triethylamine is used in hydroboration reactions of alkenes.
Borane-Triethylamine serves as a key reagent in hydroboration-oxidation protocols.

Borane-Triethylamine is utilized in reducing amides to amines.
Borane-Triethylamine is applied in the selective reduction of ketones.

Borane-Triethylamine is used in pharmaceutical synthesis where mild reducing conditions are essential.
Borane-Triethylamine is suitable for reducing nitriles to primary amines.

Borane-Triethylamine enables clean conversion of aldehydes to alcohols.
Borane-Triethylamine is used to prepare organoboranes in research labs.
Borane-Triethylamine is employed in reductive amination reactions.

Borane-Triethylamine plays a role in the synthesis of chiral compounds.
Borane-Triethylamine is favored in reactions requiring high functional group tolerance.

Borane-Triethylamine is used in carbohydrate chemistry for sugar modifications.
Borane-Triethylamine assists in the reduction of oximes to amines.

Borane-Triethylamine is used in agrochemical compound development.
Borane-Triethylamine is applied in fine chemical production.

Borane-Triethylamine is utilized for the synthesis of borinic acids.
Borane-Triethylamine is used in fragrance intermediate synthesis.
Borane-Triethylamine is a common reagent in medicinal chemistry laboratories.

Borane-Triethylamine is used in bioconjugation for selective reductions.
Borane-Triethylamine is compatible with various solvents, enhancing reaction versatility.

Borane-Triethylamine is employed in polymer precursor functionalization.
Borane-Triethylamine is used in converting alkynes to cis-alkenes via hydroboration.

Borane-Triethylamine allows selective reduction of unsaturated aldehydes.
Borane-Triethylamine helps reduce sulfoxides to sulfides.

Borane-Triethylamine is used in the transformation of enones.
Borane-Triethylamine is used in nanomaterial surface chemistry for reduction steps.
Borane-Triethylamine is involved in the preparation of borohydride intermediates.

Borane-Triethylamine is suitable for hydrogenation catalyst preparation.
Borane-Triethylamine is used to synthesize boron-containing heterocycles.

Borane-Triethylamine enables reductions without affecting sensitive functional groups.
Borane-Triethylamine is chosen for chemoselective transformations in drug development.

Borane-Triethylamine is employed in asymmetric synthesis using chiral auxiliaries.
Borane-Triethylamine assists in the formation of alcohols from epoxides.

Borane-Triethylamine is used in synthesis workflows for vitamins and cofactors.
Borane-Triethylamine is used in peptide chemistry to reduce carboxylic side chains.

Borane-Triethylamine contributes to environmental-friendly reduction alternatives.
Borane-Triethylamine is used in reaction sequences requiring anhydrous reducing agents.
Borane-Triethylamine is used in the synthesis of ligands for transition metal complexes.

Borane-Triethylamine plays a role in the functionalization of olefins.
Borane-Triethylamine is used in reducing azides to amines under mild conditions.
Borane-Triethylamine is applied in surface modification of polymers.
Borane-Triethylamine is used in chemical vapor deposition precursor modifications.

Borane-Triethylamine is used in solid-phase organic synthesis.
Borane-Triethylamine is used in enantioselective reduction of ketones.
Borane-Triethylamine aids in the conversion of imines to amines.

Borane-Triethylamine is chosen for reductions in microwave-assisted synthesis.
Borane-Triethylamine is useful for educational demonstration of hydroboration chemistry.

DESCRIPTION

Borane-Triethylamine is a clear, colorless to slightly yellowish liquid with a characteristic amine odor.
Borane-Triethylamine is typically supplied as a solution in tetrahydrofuran (THF) or dimethyl ether for stability and handling.

Borane-Triethylamine forms a stable donor-acceptor complex between borane and triethylamine.
Borane-Triethylamine is a complex formed by the coordination of borane with triethylamine.

Borane-Triethylamine is a colorless to pale yellow liquid with a strong amine-like odor.
Borane-Triethylamine provides a safer and more stable alternative to gaseous diborane.
Borane-Triethylamine is moisture-sensitive and must be stored under inert atmosphere.

Borane-Triethylamine is commonly supplied as a 1M or 2M solution in tetrahydrofuran.
Borane-Triethylamine is soluble in ether-based solvents and hydrocarbons.

Borane-Triethylamine is thermally sensitive and may decompose upon heating.
Borane-Triethylamine reacts violently with water and oxidizing agents.

Borane-Triethylamine is used extensively in organic laboratories and pilot-scale synthesis.
Borane-Triethylamine provides high selectivity and efficiency in reduction reactions.

Borane-Triethylamine is air-sensitive and reacts exothermically with water, alcohols, and acids.
Borane-Triethylamine decomposes upon exposure to moisture, releasing hydrogen gas and boric acid derivatives.
Borane-Triethylamine is pyrophoric in its pure form and must be handled under inert atmosphere.

Borane-Triethylamine is more stable than borane-THF complex and less volatile than diborane gas.
Borane-Triethylamine allows safer transport and storage of borane for laboratory use.
Borane-Triethylamine reacts readily with carbonyl groups and unsaturated bonds, allowing rapid reaction times.

Borane-Triethylamine is widely used in academic research and industrial R&D for its versatility and ease of handling.
Borane-Triethylamine can be regenerated or neutralized using peroxide solutions or alcohol quenching methods.
Borane-Triethylamine offers improved shelf life when stored properly in sealed containers under inert gas.

PROPERTIES

Chemical Formula: C6H18BN
Molecular Weight: 115.02 g/mol
Appearance: Colorless to light yellow liquid (often in solution)
Odor: Amine-like
Density: ~0.75–0.78 g/cm³ (depending on solution)
Boiling Point: ~100–125°C (complex, varies with solvent)
Solubility: Soluble in organic solvents (THF, ether); reacts with water
Vapor Pressure: Low to moderate (depends on solvent)
Flash Point: ~0–15°C (varies by formulation)
Stability: Stable under inert atmosphere; decomposes with moisture
Reactivity: Reacts with water, acids, oxidizers
Storage: Store under nitrogen or argon in tightly sealed containers
Shelf Life: Several months if unopened and moisture-free

FIRST AID

Inhalation:
Remove person to fresh air immediately.
If symptoms persist, seek medical attention.
Administer oxygen if breathing is difficult.

Skin Contact:
Flush affected area with water for at least 15 minutes.
Remove contaminated clothing and wash skin thoroughly with soap.
Seek medical advice if irritation develops.

Eye Contact:
Immediately rinse eyes with water for at least 15 minutes.
Lift eyelids and continue flushing.
Seek urgent medical attention.

Ingestion:
Do not induce vomiting.
Rinse mouth and seek immediate medical help.
Do not give anything by mouth if the person is unconscious.

Note to Physicians:
Treat symptomatically.
Borane complexes can cause delayed symptoms.
Monitor for respiratory or gastrointestinal effects.

HANDLING AND STORAGE

Handling:
Use only in well-ventilated fume hoods.
Avoid contact with air, water, or oxidizing agents.
Wear flame-resistant gloves, eye protection, and lab coat.
Use inert gas blanket when opening or transferring.

Storage:
Store in tightly sealed containers under dry inert gas (e.g., nitrogen).
Keep away from water, heat, sparks, and incompatible materials.
Maintain at 2–8°C in a secure, ventilated chemical storage area.
Label clearly and store separately from oxidizers and acids.

Spill and Leak Procedures:
Evacuate area and ventilate.
Absorb spills with inert material (vermiculite, dry sand).
Do not use water to clean.
Collect and dispose in accordance with local regulations.

Disposal:
Neutralize with alcohols or peroxide solutions under controlled conditions.
Dispose of in hazardous waste facilities according to chemical safety laws.
Do not pour into drains or waterways.