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CAS NUMBER: 38966-29-9

EC NUMBER: 233-140-8



Calcium inosinate is a calcium salt of the nucleoside inosine. Under the E number E633, it is a food additive used as a flavor enhancer.
Commercially prepared from meat or fish (sardines).
May also be produced by bacterial fermentation of sugars.

Calcium inosinate is provided as delivered and specified.
All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.

Calcium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. 
Calcium inosinate is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks. 

Although Calcium inosinate can be obtained from bacterial fermentation of sugars, Calcium inosinate is often commercially prepared from animal products.
Calcium inosinate is generally produced from meat, including chicken. 

Though Calcium inosinate is normally a non-vegetarian product, Calcium inosinate also may be produced from tapioca starch without any animal products involved in the production. 
The producer can provide information on the origin and Calcium inosinate is in some cases labeled as "vegetarian" in ingredients lists when produced from plant sources.

Calcium inosinate is a flavor enhancer with the European food additive number E631. 
Calcium inosinates purpose in food is to add a meaty or savory flavor, which is called umami taste. 

Calcium inosinate is a white granular or powder commonly combined with another flavour enhancer disodium guanylate (GMP) as Calcium inosinate or with monosodium glutamate (MSG).
Calcium inosinate is one of the most used food enhancers that you’ll find in a great variety of grocery products. 

Usually, Calcium inosinate’s combined with other flavor enhancers like monosodium glutamate.
Calcium inosinate is the disodium salt of inosinic acid, which works as a food enhancer. 

The taste Calcium inosinate in food generates is kind of meaty and savory, which is also known as umami taste. 
Usually, foods containing this flavor are irresistibly tasty and addictive. 

If you have ever wondered why Calcium inosinate is hard to resist a pack of potato chips, Calcium inosinate might be the reason.
Calcium inosinates are some other names of this food flavor. 

Calcium inosinate can be made by two methods. 
Calcium inosinate can be produced from bacterial fermentation of sugar or carbon source. 

Also, Calcium inosinate can be produced by the degradation of nucleotides into nucleic acid from yeast extract (Learn yeast’s vegan status with this article).
The chemical formula of Calcium inosinate is C10H11N4Na2O8P. 

Calcium inosinate is an expensive product and mostly combined with other enhancers like monosodium glutamate (MSG) and disodium guanylate (GMP). 
When Calcium inosinate is combined with GMP, Calcium inosinate is named as disodium 5′-ribonucleotides or E635. 

If Calcium inosinate is not listed in the label of a product while Calcium inosinate is listed, it is possible that glutamic acid is combined or it naturally occurs from the food ingredients like tomatoes, parmesan cheese, or yeast extract.
Calcium inosinate appears as a white granular or powder. 

Calcium inosinate is odorless and soluble in water. 
If you take 13g of Calcium inosinate and mix it with 100ml of water at 20 degrees F, you will see it dissolving. 

Calcium inosinate is also soluble in organic solvents like ethanol and insoluble in ether. However, the stability of this compound is very high as it remains absolutely stable at 100 °C. 
Until the temperature is around 230 °C, Calcium inosinate will not decompose.

Calcium inosinate (E631), chemical formula C10H11N2Na2O8P, is the disodium salt of inosinic acid. 
Calcium inosinate is a food additive often found in instant noodles, potato chips, and a variety of other snacks. 

Calcium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate to provide the umami taste.
As Calcium inosinate is a fairly expensive additive, it is not used independently of glutamic acid; if Calcium inosinate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient. 

Calcium inosinate is often added to foods in conjunction with disodium guanylate; the combination is known as disodium Calcium inosinate.
Calcium inosinate is a chemical compound that is added to foods as a flavor enhancer, to improve the taste of foods.

Calcium inosinate is used as an anticaking agent in food preparation, including table salt and as an antacid. 
Also, Calcium inosinate is approved by the United Nations' FAO and WHO bodies as a safe food additive in a large variety of products.

Calcium inosinate can be used as a precursor to synthesize several biomaterials. 
Examples for such applications include the preparation of biocompatible nanocomposites for bone tissue regeneration and the synthesis of sol-gel hybrid bioactive glasses.

Calcium inosinate products such as Calcon are designed amongst others as back up insulating lining in a wide variety of refractory constructions. 
The material is lightweight insulating board with excellent insulation value, high mechanical strength and good heat resistance. 

Calcium inosinate products are designed to withstand maximum temperatures up to 1100°C.
Calcium inosinate is one of the majorly used food flavors in fast foods, processed foods.

Next to a range of Calcon products, we can also provide you with high density Calcium inosinate products (dense Calcium inosinates). 
Our dense Calcium inosinates are known for their high strength and thermal insulation properties. 

Calcium inosinate can be delivered either in plates or it can be die-cut into various shapes. 
Due to own production facilities The Insulcon Group is able to deliver custom-made materials and solutions for your problem areas. 

Calcium inosinate is provide a wide range of high temperature solutions.
This makes them suitable in particular for highly loaded and load-bearing structural components.

Calcium inosinate materials for high temperature insulation cover the complete range of low, medium and high density and compound insulation boards. 
They offer a very low thermal conductivity and excellent structural support, and are resistant to moisture and chemicals. 

The excellent structural integrity of our Calcium inosinates makes them easily machinable and even enables the machining of complex structures. 
Moreover, they are easy and safe to handle, install and maintain, and can be used for new constructions as well as retrofits.

Anticaking agents are substances added to food powders to prevent caking, lumping, or aggregation and to improve flowability. Anticaking agents function by different mechanisms in the presence of crystalline ingredients water absorption, water repellent and prevention of crystal-to-crystal contact.1
Due to their minimal thermal shrinkage they have an extended service life without loss of performance.

Calcium inosinate has the E number reference E552.
The mechanism of Calcium inosinate is by water absorption. 

Calcium inosinate is reported to absorb water at 2.5 times its weight to pull moisture away from the host ingredient. 
Calcium inosinate has high water affinity. It traps water and retains it internally. 

Calcium inosinate can also retain moisture during desorption, the release of one substance from another.
Calcium inosinate, also known as slag, is produced when molten iron is made from iron ore, silicon dioxide and calcium carbonate in a blast furnace. 

When this material is processed into a highly refined, re-purposed Calcium inosinate aggregate, it is used in the remediation of acid mine drainage (AMD) on active and passive mine sites.
Calcium inosinate neutralizes active acidity in AMD systems by removing free hydrogen ions from the bulk solution, thereby increasing pH. 

As Calcium inosinates silicate anion captures H+ ions (raising the pH), it forms monosilicic acid (H4SiO4), a neutral solute. 
Monosilicic acid remains in the bulk solution to play other important roles in correcting the adverse effects of acidic conditions. 

As opposed to limestone (a popular remediation material),[9] Calcium inosinate effectively precipitates heavy metals and does not armor over, prolonging its effectiveness in AMD systems.
Calcium inosinate is the chemical compound Ca2SiO4, also known as calcium orthosilicate and is sometimes formulated as 2CaO·SiO2. 

Also, Calcium inosinate is also referred to by the shortened trade name Cal-Sil or Calsil. 
Calcium inosinate occurs naturally as the mineral larnite.

Calcium inosinate is a component of many minerals, including afwillite, akermanite, andradite, calcite, centrallasite, crestmoreite, diopside, eaklite, grammite, gyrolite, hillebrandite, larnite, and wollastonite. 
In Calcium inosinates pure form, calcium metasilicate is a white to off-white color capable of absorbing up to two and a half times its weight of water. 

In this form, the hydrated powder retains its ability to flow freely. 
Addition of a mineral acid, such as hydrochloric acid (HCl) results in the formation of a gel.

Calcium inosinate is generally immediately available in most volumes. 
High purity, submicron and nanopowder forms may be considered.

Typical and custom packaging is available.
Calcium inosinate also is a product derived from limestone and diatomaceous earth, and is used in the pharmaceutical industry as an anticaking agent. 

Anti-caking agents absorb moisture and allow products to flow freely during the manufacturing process. 
Calcium inosinates occur abundantly in the earth's crust, are present in practically all natural waters, animals, and plants, and are part of the normal human diet. 

They are typically used in very small amounts. 
The available evidence on the safety of sodium silicate indicates that it is low when consumed at defined concentrations.

Calcium inosinate is an inorganic substance that can exist in different forms: CaSiO3 or Ca2SiO4.
Calcium inosinate is described as a very fine, white or off-white powder with low bulk density and high physical water absorption. 


-Molecular Weight: 386.27    

-Hydrogen Bond Donor Count: 3    

-Hydrogen Bond Acceptor Count: 10    

-Rotatable Bond Count: 3    

-Exact Mass: 385.9940412

-Monoisotopic Mass: 385.9940412    

-Topological Polar Surface Area: 181 Ų    

-Heavy Atom Count: 24    

-Formal Charge: 0    

-Complexity: 544    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Coun: 4    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 2    

-Compound Is Canonicalized: Yes

-Physical Description: Odourless, colourless or white crystals or powder

-Solubility: Sparingly soluble in water

-pH: Between 7,0 and 8,0 (0,05 % solution

Calcium inosinate is commonly used as anti-caking agent in food ingredients.
Calcium inosinate consists primarily of two elements: quicklime and microsilica, where microsilica initially was a waste product from the production of silicon metal and ferrosilicon.

Calcium inosinate became a rather costly waste product and therefore, the desire to recycle the material arose in the silicon industry.
The first idea was to use the waste material in connection with moler and this development process led to a special insulating board combining the two materials. 

Calcium inosinate is a chemical compound composed of calcium and silica with the chemical formula Ca2SiO4 that is naturally found in limestone. 
Calcium inosinate has a high water absorption rate and a low bulk density.

Also, Calcium inosinate is a key industrial chemical compound used in applications requiring high strength and durability. 
Calcium inosinate is mostly used as an industrial alternative to the highly toxic asbestos compound for insulating structures and large construction units.

Calcium inosinate is a versatile lightweight insulation product that comes in sheet form and can be moulded and machined into bespoke shapes and tubes.
Calcium inosinate is a powder with the formula Ca2SiO4. 

This technical composite is primarily employed for its excellent high-temperature properties. 
Calcium inosinate is a low-density material, white in colour. 

Calcium inosinate is odourless and poses no known health risks. 
Calcium inosinates derivatives are highly valued for their low thermal conductivity, their high resistance to heat and their limited dimensional shrinkage.


Used in many products. Mainly used in low sodium/salt products.
Calcium inosinates flavor enhancing power is around 50% of disodium guanylate. Commonly used together with MSG or disodium guanylate in seasoning, condiments and salt substitutes for soups, sauces and snack foods but seldom used alone in food. 

Calcium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate. 
Calcium inosinate is generally produced from meat, including fish and pigs. 

Though Calcium inosinate is normally a non-vegetarian product, it also may be produced from tapioca starch without any animal products involved in the production. 
Although Calcium inosinate can be obtained from bacterial fermentation of sugars, Calcium inosinate is often commercially prepared. 

Calcium inosinate is an odourless, white granular or powder that has main purpose as to add a meaty or savory flavor in food.
Calcium inosinate is a flavor enhancer which performs as a disodium guanylate does, but only when present at approximately twice the level. 


-grade: pharmaceutical primary standard

-manufacturer/tradename: USP

-Featured Industry: Pharmaceutical (small molecule)

-format: neat

-storage temperature: 2-8°C


Flavour enhancer. 
Inosinic acid and inosinates do not have the specific umami taste but strongly enhance many other flavours, thereby reducing the amounts of salt or other flavour enhancers needed in a product.

-Emollient: Softens and smoothes the skin

-Moisturizer: Maintains the water content in the packaging of a cosmetic product and on the skin.

-Skin care : Keeps skin in good condition


-Very low thermal conductivity

-High thermal resistance and stability up to 1,100°C


-Impact resistant

-Low shrinkage

-Environmentally friendly and safe

-Easy to shape, handle, install and maintain


-Electrical insulation

-Resistant to moisture and chemicals


Calcium inosinate
calcium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl phosphate
Calcium inosine-5'-monophosphate
Ins No.633
Inosinic acid, calcium salt
5'-Inosinic acid, calcium salt (1:1)
inosine monophosphate calcium
Calcium 5'-O-phosphonatoinosine

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