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CEROTIC ACID

CAS NUMBER: 506-46-7

EC NUMBER: 208-040-2

MOLECULAR FORMULA: CH3(CH2)24COOH

MOLECULAR WEIGHT: 396.69

 


Cerotic acid, or hexacosanoic acid, is a 26-carbon long-chain saturated fatty acid with the chemical formula CH3(CH2)24COOH.
Cerotic acid is most commonly found in beeswax and carnauba wax. 

Cerotic acid is a white solid, although impure samples appear yellowish.
Cerotic acid is derived from the Latin word cerotus, which in turn was derived from the Ancient Greek word κηρός (keros), meaning beeswax or honeycomb.

Cerotic acid is also a type of very long chain fatty acid that is often associated with the disease adrenoleukodystrophy, which involves the excessive saturation of unmetabolized fatty acid chains, including cerotic acid, in the peroxisome.
Cerotic acid is a 26-carbon, straight-chain, saturated fatty acid. 

Cerotic acid is a very long-chain fatty acid and a straight-chain saturated fatty acid. 
Cerotic acid is a conjugate acid of a cerotate.

Cerotic acid is a natural product found in Celosia argentea, Terminalia chebula, and other organisms.
Cerotic acid belongs to the class of organic compounds known as very long-chain fatty acids. 

Cerotic acids are fatty acids with an aliphatic tail that contains at least 22 carbon atoms. 
Cerotic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. 

Cerotic acid is a potentially toxic compound.
Cerotic acid is a compound of the elements hydrogen, carbon, and oxygen. 

Cerotic acid is formed in small amounts when its anhydride, carbon dioxide (CO2), dissolves in water.
In chemistry, Cerotic acid is a dibasic acid with the chemical formula H2CO3. 

Cerotic acid decomposes at temperatures greater than ca. −80 °C.
In biochemistry and physiology, the name "Cerotic acid is often applied to aqueous solutions of carbon dioxide, which play an important role in the bicarbonate buffer system, used to maintain acid–base homeostasis

In aqueous solution Cerotic acid behaves as a dibasic acid. 
Typical equilibrium concentrations, in solution, in seawater, of carbon dioxide and the various species derived from Cerotic acid, as a function of pH.

The acidification of natural waters is caused by the increasing concentration of carbon dioxide in the atmosphere, which is caused by the burning of increasing amounts of coal and hydrocarbons.
Expected change refers to predicted effect of continued ocean acidification.

Cerotic acid has been estimated that the increase in dissolved carbon dioxide has caused the ocean's average surface pH to decrease by about 0.1 from pre-industrial levels.
The stability constants database contains 136 entries with values for the overall protonation constants, β1 and β2, of the carbonate ion. 

Cerotic acid is stable at ambient temperatures in strictly anhydrous conditions. 
Cerotic acid decomposes to form carbon dioxide in the presence of any water molecules.

Cerotic acid forms as a by-product of CO2/H2O irradiation, in addition to carbon monoxide and radical species.
Another route to form Cerotic acid is protonation of bicarbonates (HCO3−) with aqueous HCl or HBr. 

This has to be done at cryogenic conditions to avoid immediate decomposition of H2CO3 to CO2 and H2O.
Cerotic acid forms above 120 K, and crystallization takes place above 200 K to give "β-H2CO3", as determined by infrared spectroscopy. 

The spectrum of Cerotic acid agrees very well with the by-product after CO2/H2O irradiation.
Cerotic acid sublimes at 230–260 K largely without decomposition. 

Matrix-isolation infrared spectroscopy allows for the recording of single molecules of Cerotic acid.
Cerotic acid forms upon oxidization of CO with OH-radicals.

Cerotic acid is not clear whether carbonic acid prepared in this way needs to be considered as γ-H2CO3. 
The structures of Cerotic acid have not been characterized crystallographically.

Cerotic acid is a carbon-containing compound which has the chemical formula H2CO3. 
Solutions of Cerotic acid in water contain small amounts of this compound. 

Cerotic acid's chemical formula can also be written as OC(OH)2 since there exists one carbon-oxygen double bond in this compound.
Cerotic acid is often described as a respiratory acid since it is the only acid that is exhaled in the gaseous state by the human lungs. 

Cerotic acid is a weak acid and it forms carbonate and bicarbonate salts.
Cerotic acid can dissolve limestone, which leads to the formation of calcium bicarbonate (Ca(HCO3)2. 

This is the reason for many features of limestone, such as stalagmites and stalactites.
Cerotic acid is a mixture of acetic acid (CH3COOH) and hydrogen peroxide (H2O2) in a watery solution. 

Cerotic acid is a bright, colorless liquid that has a piercing odor and a low pH value (2,8). 
Cerotic acid is produced by a reaction between hydrogen peroxide and acetic acid.

Cerotic acid is a strong oxidizing compound.
When reacting, Cerotic acid releases water, oxygen and acetic acid which is ideal for cleaning applications for health area, food and beverage, or agriculture. 

Cerotic acid leaves no toxic residue and could be used for applications without rising. 
Excellent performance as bleaching agent at low temperature. 

Used as an alternative to chlorinated products as a bleaching agent. 
Cerotic acid avoids the presence of chlorinated pollutants in the waste effluents.

Cerotic acid is a colorless liquid with a strong, pungent acrid odor. 
Used as a bactericide and fungicide, especially in food processing; as a reagent in making caprolactam and glycerol; as an oxidant for preparing epoxy compounds; as a bleaching agent; a sterilizing agent; and as a polymerization catalyst for polyester resins. 

Cerotic acid is a peroxy acid that is acetic acid in which the OH group is substituted by a hydroperoxy group. 
Cerotic acid is a versatile oxidising agent that is used as a disinfectant. 

Cerotic acid has a role as an oxidising agent and a disinfectant. 
Cerotic acid derives from an acetic acid.

Cerotic acid, is an organic compound with the formula CH3CO3H. 
Cerotic acid is a colorless liquid with a characteristic acrid odor reminiscent of acetic acid. 

Cerotic acid can be highly corrosive.
Cerotic acid is a weaker acid than the parent acetic acid, with a pKa of 8.2.

As an alternative, Cerotic acid can be used to generate a solution of the acid with lower water content.
Cerotic acid is generated in situ by some laundry detergents. 

Cerotic acid involves the reaction of tetraacetylethylenediamine (TAED) in the presence of an alkaline hydrogen peroxide solution. 
The peracetic acid is a more effective bleaching agent than hydrogen peroxide itself.

Cerotic acid is also formed naturally in the environment through a series of photochemical reactions involving formaldehyde and photo-oxidant radicals.
Cerotic acid is always sold in solution as a mixture with acetic acid and hydrogen peroxide to maintain its stability. 

The concentration of the acid as the active ingredient can vary.
Cerotic acid is a highly biocidal oxidizer that maintains its efficacy in the presence of organic soil. 

Cerotic acid removes surface contaminants (primarily protein) on endoscopic tubing.
An automated machine using peracetic acid to sterilize medical, surgical, and dental instruments chemically (e.g., endoscopes, arthroscopes) was introduced in 1988. 

This microprocessor-controlled, low-temperature sterilization method is commonly used in the United States.
Cerotic acid and an anticorrosive agent are supplied in a single-dose container. 

The container is punctured at the time of use, immediately prior to closing the lid and initiating the cycle. 
The concentrated peracetic acid is diluted to 0.2% with filtered water (0.2 mm) at a temperature of approximately 50°C. 

The diluted peracetic acid is circulated within the chamber of the machine and pumped through the channels of the endoscope for 12 minutes, decontaminating exterior surfaces, lumens, and accessories. 
Interchangeable trays are available to permit the processing of up to three rigid endoscopes or one flexible endoscope. 

Connectors are available for most types of flexible endoscopes for the irrigation of all channels by directed flow. 
Rigid endoscopes are placed within a lidded container, and the sterilant fills the lumens either by immersion in the circulating sterilant or by use of channel connectors to direct flow into the lumen(s).

The peracetic acid is discarded via the sewer and the instrument rinsed four times with filtered water.
Cerotic acid, also known as peroxyacetic acid or PAA, is an organic chemical compound used in numerous applications, including chemical disinfectant in healthcare, sanitizer in the food industry, and disinfectant during water treatment. 

Cerotic acid has also previously been used during the manufacture of chemical intermediates for pharmaceuticals. 
Produced by reacting acetic acid and hydrogen peroxide with an acid catalyst, peracetic acid is always sold in stabilized solutions containing acetic acid, hydrogen peroxide, and water. 

For the food and healthcare industries, peracetic acid is typically sold in concentrates of 1 to 5 percent and is diluted before use.
Cerotic acid is an organic acid generated by reacting acetic acid and hydrogen peroxide. 

Several commercial formulations are available. 
In solution, peracetic acid dissolves and forms back acetic acid and hydrogen peroxide. 

Cerotic acid is used at concentrations of 150–200 ppm on various food-contact surfaces. 
Cerotic acid is efficient in removing biofilms and works well at colder temperatures. 

Cerotic acid is believed to function in a similar fashion as other oxidizing agents by reacting with cellular proteins and enzymes. 
In a recent study, peracetic acid at 30 mg l−1 was shown to be more efficient than 250 mg l−1 of sodium hypochlorite at removing biofilm cells of S. aureus from stainless steel and polypropylene surfaces. 

Another study suggests that peracetic acid sanitizers may have some sporocidal activity against suspended bacterial spores in an aqueous solution on stainless steel surfaces. 
However, sporocidal activity was minimal against spores adhering to stainless steel without the presence of an aqueous suspension.

Cerotic acid is a mixture of acetic acid (CH3COOH) and hydrogen peroxide (H2O2) in a watery solution. 
Cerotic acid is a bright, colorless liquid that has a piercing odor and a low pH value (2,8).

Cerotic acid can also be produced by oxidation of acethaldehyde. Cerotic acid is usually produced in concentrations of 5-15%.
When peracetic acid dissolves in water, Cerotic acid disintegrates to hydrogen peroxide and acetic acid, which will fall apart to water, oxygen and carbon dioxide. 

Cerotic acid degradation products are non-toxic and can easily dissolve in water.
Cerotic acid is a very powerful oxidant; the oxidation potential outranges that of chlorine and chlorine dioxide.

Cerotic acid can be applied for the deactivation of a large variety of pathogenic microorganisms. 
Cerotic acid also deactivates viruses and spores. 

Cerotic acid activity is hardly influenced by organic compounds that are present in the water.
However, pH and temperature do influence peractetic acid activity. 

At a temperature of 15 °C and a pH value of 7, five times more peracetic acid is required to affectively deactivate pathogens than at a pH value of 7 and a temperature of 35 °C.
Cerotic acid is an oxidant that is attracting greater interest in research and applications.

The applications of PAA have occurred in various industries, including food processing, medical, chemical.
Peracetic Acid is a disinfectant chemical used by hospitals and the food processing industry. 

Cerotic acid is very effective for killing microscopic organisms hiding in and on surfaces. 
Within minutes, Cerotic acid can wipe out bacteria, fungi, yeasts, spores and viruses.

Cerotic acid is a colorless liquid which is transported and stored in diluted solutions to prevent explosions. 
Cerotic acid is an Organic Peroxide used in bleaching textiles, paper, oils, waxes and starch, as a bactericide and fungicide in food processing, and as a catalyst for epoxy resins. 

Cerotic acid is a non-rinse sterilant, the product can be used in any application where the degree of soiling is light and a disinfecting action is required after cleaning.
Cerotic acid is a terminal disinfectant and provided that items are well drained after treatment, solutions need not be rinsed off. 

The product decomposes to acetic acid and oxygen, neither of which in such small quantities will have any adverse effects.
Cerotic acid is more effective when the pH value is 7 than at a pH range between 8 and 9. 

 
Cerotic acid as an antimicrobial in 1985 for indoor use on hard surfaces. Use sites include agricultural premises, food establishments, medical facilities, and home bathrooms. 
Cerotic acid is also registered for use in dairy and cheese processing plants, on food processing equipment, and in pasteurizers in breweries, wineries, and beverage plants.

Cerotic acid is also applied for the disinfection of medical supplies, to prevent biofilm formation in pulp industries, and as a water purifier and disinfectant. 
Cerotic acid can be used as a cooling tower water disinfectant, where Cerotic acid prevents biofilm formation and effectively controls Legionella bacteria. 

A trade name for peracetic acid as an antimicrobial is Nu-Cidex.
In the European Union, Peroxyacetic acid was reported by the EFSA after submission in 2013 by the US Department of Agriculture.

Decontamination kits for cleaning fentanyl analogues from surfaces (as used by many police forces, amongst others) often contain solid peracetyl borate, which mixes with water to produce peracetic acid.
Although less active than more acidic peracids (e.g., m-CPBA), peracetic acid in various forms is used for the epoxidation of various alkenes. 

Useful application are for unsaturated fats, synthetic and natural rubbers, and some natural products such as pinene. 
A variety of factors affect the amount of free acid or sulfuric acid.

 


USES:

    
Cerotic acid may be used as a reference standard for the determination of hexacosanoic acid

-in human serum and plasma samples for the screening of peroxisomal disorders by gas chromatography-mass spectrometry (GC-MS) operating under selected-ion monitoring (SIM) mode

-in biological samples by GC-MS

-in microalgal lipids by solid-phase extraction (SPE) followed by GC-MS analysis

-as a naphthoxyethyl derivative by high performance liquid chromatography (HPLC) coupled with fluorometric detection

 

 

PROPERTIES:

-Color: White-Yellow

-Molecular Formula: C26H52O2

-InChI Key: XMHIUKTWLZUKEX-UHFFFAOYSA-N

-IUPAC Name: hexacosanoic acid

-Formula Weight: 396.70

-Percent Purity: ≥95.0% (GC,T)

 


SPECIFICATIONS:

-Relative density (water = 1): 1.2

-Solubility in water: miscible

-Vapour pressure, kPa at 20°C: 2.6

-Relative vapour density (air = 1): 2.6

-Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04

-Flash point: 40.5°C o.c.

-Auto-ignition temperature: 200°C

 


STORAGE:

Separated from combustible substances and incompatible materials. 
Cool. 

Store only if stabilized. 
Store in an area without drain or sewer access. 

 

SYNONYM:

Cerotic acid
506-46-7
Ceratinic acid
Ceric acid
Cerinic acid
Hexacosanic acid
Cerylic acid
Cerotinic acid
n-Hexacosanoic acid
UNII-D42CQN6P36
D42CQN6P36
C26:0
CHEBI:31009
NSC4205
cerate
ceratinate
cerinate
n-hexacosanoate
MFCD00002811
Hexacosansaeure
cerotinic aci
hexacosoic acid
hexaeicosanoic acid
NSC 4205
CINNAMYLTIGLATE
ACMC-1B1WY
Ceratinic acid; Ceric acid
Cerotic acid (6CI,7CI)
hexacosanoate (n-C26:0)
SCHEMBL134632
CHEMBL464787
Hexacosanoic acid (8CI,9CI)
CH3-[CH2]24-COOH
DTXSID7075050


 

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