PRODUCTS

CETANOL H

CAS Number: 36653-82-4
EC Number: 253-149-0
Molecular Formula: C16H34O

DESCRIPTION:
Cetanol h /ˈsiːtəl/, also known as hexadecan-1-ol and palmityl alcohol, is a C-16 fatty alcohol with the formula CH3(CH2)15OH.
At room temperature, Cetanol h takes the form of a waxy white solid or flakes.
The name cetyl derives from the whale oil (cetacea oil, from Latin: cetus, lit. 'whale', from Ancient Greek: κῆτος, romanized: kētos, lit. 'huge fish') from which it was first isolated

Cetanol h, also known as 1-hexadecanol or n-hexadecyl alcohol, is a 16-C fatty alcohol with the chemical formula CH3(CH2)15OH.
Cetanol h can be produced from the reduction of palmitic acid.

Cetanol h is present in a waxy white powder or flake form at room temperature, and is insoluble in water and soluble in alcohols and oils.
Discovered by Chevrenl in 1913, Cetanol h is one of the oldest known long-chain alcohol.
Cetanol h may be contained in cosmetic and personal care products such as shampoos, creams and lotions.

Mainly Cetanol h is used as an opacifier, emulsifier, and thickening agent that alter the thickness of the liquid, and increase and stabilize the foaming capacity.
Due to its water-binding property, Cetanol h is commonly used as an emollient that prevents drying and chapping of the skin.

According to the FDA Code of Federal Regulations, Cetanol h is a safe synthetic fatty acid in food and in the synthesis of food components under the condition that it contain not less than 98 percent of total alcohols and not less than 94 percent of straight chain alcohols.
Cetanol h is also listed in the OTC ingredient list as a skin protectant for skin irritations caused by poison ivy, oak, sumac, and insect bites or stings.

Cetanol h is reported to be a mild skin or eye irritant.
Cetanol h is a synthetic, solid, fatty alcohol and nonionic surfactant.
Cetanol h is used as an emulsifying agent in pharmaceutical preparations.
1-Hexadecanol is a natural product found in Mikania cordifolia, Cichorium endivia, and other organisms with data available.

Cetanol h is one of the most common ingredients found in cosmetic, skin care, and hair care products.
Cetanol h is a white and waxy ingredient that acts as a thickening agent in products.
Cetanol h also binds the ingredients together and prevents them from separating.

Apart from this, Cetanol h has moisturizing properties and is non-comedogenic, that is, Cetanol h does not clog pores.
The chemical formula of Cetanol h is C16H34O.
What is Cetanol h used for?

Cetanol h is found in numerous cosmetic and skin care products - moisturizers, makeup, shampoos, soap, etc. This is owing to the variety of benefits offered:

For Skin:
Cetanol h acts as a moisturizing agent and an opacifier.
Cetanol h makes the skin hydrated and soft without clogging the pores or causing acne.
Cetanol h is good for the skin and is used in a range of products

For Hair:
Cetanol h acts as a thickening agent and allows hair care products to be applied easily on the shafts without the product being too flowy.
Moreover, Cetanol h is an emollient that keeps the ingredient from separating in a formulation

In Cosmetics, since Cetanol h is a waxy ingredient, Cetanol h greatly enhances the texture of cosmetic products and improves the spreadability of the formulations. In products like lipsticks, Cetanol h is the ingredient that helps the color adhere to the lips
Origin of Cetanol h:

Cetanol h is a natural ingredient that is extracted from vegetable, coconut, or palm oil.
Cetanol h was first discovered by a French chemist - Michael Chevreul - in 1817.
He obtained this thick and waxy ingredient from sperm whale oil but today Cetanol h is mainly produced by many other natural sources.
What does Cetanol h do in a formulation?
•   Emollient
•   Moisturising
•   Opacifying
•   Viscosity controlling

SAFETY PROFILE OF CETANOL H:
Cetanol h is largely safe for use in cosmetic and skin care products.
However, some people might experience allergies such as inflamed or red skin.
Therefore, a patch test is recommended prior to full usage.
Cetanol h is safe for pregnant women too.

CAS Number: 36653-82-4
EC Number: 253-149-0
Molecular Formula: C16H34O

PREPARATION OF CETANOL H:
Cetanol h was discovered in 1817 by the French chemist Michel Chevreul when he heated spermaceti, a waxy substance obtained from sperm whale oil, with caustic potash (potassium hydroxide).
Flakes of Cetanol h were left behind on cooling.
Modern production is based around the reduction of palmitic acid, which is obtained from palm oil.

USES OF CETANOL H:
Cetanol h is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions.

Cetanol h is also employed as a lubricant for nuts and bolts, and is the active ingredient in some "liquid pool covers" (forming a non-volatile surface layer to reduce water evaporation, related latent vaporization heat loss, and thus to retain heat in the pool).
Moreover, Cetanol h can also be used as a non-ionic co-surfactant in emulsion applications

CAS Number: 36653-82-4
EC Number: 253-149-0
Molecular Formula: C16H34O

CHEMICAL AND PHYSICAL PROPERTIES OF CETANOL H:
Chemical formula:   C16H34O
Molar mass:   242.447 g•mol−1
Appearance:   White crystals or flakes
Odor:   Very faint, waxy
Density:   0.811 g/cm3
Melting point:   49.3 °C (120.7 °F; 322.4 K)
Boiling point:   344 °C (651 °F; 617 K)
Solubility in water:   Insoluble
Solubility:
Very soluble in ether, benzene, and chloroform.
Soluble in acetone.
Slightly soluble in alcohol.
log P:   7.25[2]
Acidity (pKa):   16.20
Magnetic susceptibility (χ):   −183.5•10−6 cm3/mol
Refractive index (nD):   1.4283 (79 °C)
Viscosity:   53 cP (75 °C)
Flash point:   185 °C (365 °F; 458 K)
Molecular Weight:   242.44
XLogP3:   7.3
Hydrogen Bond Donor Count:   1
Hydrogen Bond Acceptor Count:   1
Rotatable Bond Count:   14
Exact Mass:   242.260965704
Monoisotopic Mass:   242.260965704
Topological Polar Surface Area:   20.2 Å²
Heavy Atom Count:   17
Formal Charge:   0
Complexity:   123
Isotope Atom Count:   0
Defined Atom Stereocenter Count:   0
Undefined Atom Stereocenter Count:   0
Defined Bond Stereocenter Count:   0
Undefined Bond Stereocenter Count:   0
Covalently-Bonded Unit Count:   1
Compound Is Canonicalized:   Yes

SAFETY INFORMATION ABOUT CETANOL H:
First-aid measures:
Description of necessary first-aid measures:
If inhaled:

Move the victim into fresh air.
If breathing is difficult, give oxygen.
If not breathing, give artificial respiration and consult a doctor immediately.
Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact:
Take off contaminated clothing immediately.
Wash off with soap and plenty of water.
Consult a doctor.

Following eye contact:
Rinse with pure water for at least 15 minutes.
Consult a doctor.

Following ingestion:
Rinse mouth with water. Do not induce vomiting.
Never give anything by mouth to an unconscious person.
Call a doctor or Poison Control Center immediately.

Fire-fighting measures:
Suitable extinguishing media:
Use dry chemical, carbon dioxide or alcohol-resistant foam.

Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.

Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Avoid dust formation.
Avoid breathing mist, gas or vapours.
Avoid contacting with skin and eye.

Use personal protective equipment.
Wear chemical impermeable gloves.
Ensure adequate ventilation.
Remove all sources of ignition.
Evacuate personnel to safe areas.
Keep people away from and upwind of spill/leak.

Environmental precautions:
Prevent further spillage or leakage if it is safe to do so.
Do not let the chemical enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Collect and arrange disposal.

Keep the chemical in suitable and closed containers for disposal.
Remove all sources of ignition.
Use spark-proof tools and explosion-proof equipment.
Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

Handling and storage:
Precautions for safe handling:
Handling in a well ventilated place.

Wear suitable protective clothing.
Avoid contact with skin and eyes.
Avoid formation of dust and aerosols.
Use non-sparking tools.
Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities:
Store the container tightly closed in a dry, cool and well-ventilated place.
Store apart from foodstuff containers or incompatible materials.

Appropriate engineering controls:
Ensure adequate ventilation.
Handle in accordance with good industrial hygiene and safety practice.
Set up emergency exits and the risk-elimination area.

Individual protection measures, such as personal protective equipment (PPE):
Eye/face protection:
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection:
Wear fire/flame resistant and impervious clothing.
Handle with gloves.

Gloves must be inspected prior to use.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection:
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

SYNONYMS OF CETANOL H:
MESH ENTRY TERMS:
1-hexadecanol
cetanol
cetyl alcohol
cetyl alcohol, 14C-labeled
cetyl alcohol, aluminum salt
hexadecan-1-ol
n-hexadecanol

Depositor-Supplied Synonyms:
1-Hexadecanol
cetyl alcohol
Hexadecan-1-ol
36653-82-4
HEXADECANOL
Cetanol
Palmityl alcohol
Hexadecyl alcohol
N-Hexadecanol
n-1-Hexadecanol
n-Cetyl alcohol
Cetaffine
Cetylol
Cetal
Ethal
Ethol
Cetylic alcohol
n-Hexadecyl alcohol
Loxanwachs SK
Crodacol C
Loxanol K extra
1-Hexadecyl alcohol
Elfacos C
Loxanol K
Crodacol-CAS
Crodacol-CAT
Siponol wax-A
Atalco C
Cetalol CA
Siponol CC
Lanol C
1-Cetanol
Hyfatol 16
Cachalot C-50
Cachalot C-51
Cachalot C-52
Alcohol C-16
Product 308
Aldol 54
Dytol F-11
Adol
palmitic alcohol
Cyclal cetyl alcohol
Alfol 16
Lorol 24
Adol 52
Adol 54
Adol 52 NF
Hyfatol
Epal 16NF
1-Hexadecyl alc
16-Hexadecanol
C16 alcohol
Adol 520
n-Hexadecan-1-ol
Cetylalkohol
Isocetyl alcohol
1-Hexanedecanol
FEMA No. 2554
Isohexadecyl alcohol
cetylalcohol
SSD RP
Normal primary hexadecyl alcohol
CO-1670
CO-1695
Cetyl alchol
Lipocol C
Fancol CA
Cetyl alcohol NF
Crodacol C70
Rita CA
1-Hydroxyhexadecane
Cetanol (TN)
Lanette 16
Philcohol 1600
Cetyl alcohol (NF)
Cetyl alcohol [NF]
Lorol C16
LorolL 24
Cachalot C-50 NF
Adol 52NF
Alcohols, C14-18
NSC-4194
936JST6JCN
67762-30-5
CHEBI:16125
NSC4194
NCGC00159368-02
NCGC00159368-05
DSSTox_CID_7991
DSSTox_RID_78633
DSSTox_GSID_27991
Hexadecanol (VAN)
Fatty alcohol(C16)
Caswell No. 165D
FEMA Number 2554
Hexadecyl alcohol, normal
CAS-36653-82-4
HSDB 2643
NSC 4194
EINECS 253-149-0
UNII-936JST6JCN
EPA Pesticide Chemical Code 001508
Cetyl alcohol (hexadecanol)
BRN 1748475
hexadecylalcohol
AI3-00755
Hexadecanol NF
Alcohol cetylicus
Ceraphyl ICA
Crodacol C95NF
Dehydag wax 16
Eutanol G16
Crodacol C95 NF
Laurex 16
MFCD00004760
Alfol 16RD
SSD (Salt/Mix)
Cetanol (JP17)
Epal 16
Hyfatol 16-95
Kalcol 6098
Loxiol VPG 1743
1-Hexadecanol, 95%
SSD RP (Salt/Mix)
CETANOL [JAN]
bmse000487
CHEMBL706
Michel XO-150-16
EC 253-149-0
Fatty alcohols(c12-16)
1-Hexadecanol, >=99%
CETYL ALCOHOL [II]
CETYL ALCOHOL [MI]
SCHEMBL3381
CETYL ALCOHOL [HSDB]
CETYL ALCOHOL [INCI]
124-29-8
4-01-00-01876 (Beilstein Handbook Reference)
1-HEXADECANOL [FHFI]
CETYL ALCOHOL [VANDF]
CETYL ALCOHOL [MART.]
CETYL ALCOHOL [USP-RS]
CETYL ALCOHOL [WHO-DD]
CETYL ALCOHOL [WHO-IP]
DTXSID4027991
AMY6070
Cetyl alcohol, analytical standard
Cetyl alcohol, puriss., 95.0%
HMS3652H05
CS-D1348
HY-B1465
ZINC8214519
EINECS 252-964-9
Tox21_111609
Tox21_300325
CETYL ALCOHOL [EP MONOGRAPH]
LMFA05000061
s4173
STL283943
UNII-1800H64066
AKOS005287456
Tox21_111609_1
1-Hexadecanol, ReagentPlus(R), 99%
CCG-266894
DB09494
ALCOHOL CETYLICUS [WHO-IP LATIN]
NCGC00159368-03
NCGC00159368-04
NCGC00159368-06
NCGC00254286-01
BS-16666
Cetyl alcohol, puriss., >=99.0% (GC)
FT-0701357
FT-0707360
H0071
SW219201-1
Cetyl alcohol, SAJ special grade, >=98.0%
Cetyl alcohol, Selectophore(TM), >=99.0%
EN300-19351
1-Hexadecanol, Vetec(TM) reagent grade, 94%
C00823
D00099
AB01566915_01
Q161632
SR-01000944409
SR-01000944409-1
1800H64066
810F139F-C57E-4DF1-916A-A320AD0DAF4D
F0001-1047
Cetyl alcohol, European Pharmacopoeia (EP) Reference Standard
Cetyl alcohol, United States Pharmacopeia (USP) Reference Standard
Cetyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material