CRYOFLUORANE

Cryofluorane is a fully halogenated chlorofluorocarbon historically used as a refrigerant, aerosol propellant, heat-transfer fluid, solvent, foam-blowing agent, dielectric fluid, and fire-suppression material.
Cryofluorane is normally handled as a colorless, nonflammable liquefied compressed gas that becomes gaseous above its boiling point of approximately 3.6°C.
Cryofluorane is now subject to severe production, import, emission, and use restrictions because CFC-114 is a Class I ozone-depleting substance with substantial long-term climate impact.

CAS Number: 76-14-2
EC Number: 200-937-7
Molecular Formula: C2Cl2F4
Molecular Weight: 170.92 g/mol

Synonyms: Cryofluorane, Cryofluoran, CFC-114, CFC 114, Refrigerant 114, Refrigerant R-114, R-114, R114, Freon 114, Freon® 114, Genetron 114, Genetron® 114, Genetron 316, Arcton 114, Arcton 33, Frigen 114, Frigiderm, Fluorocarbon 114, FC-114, F-114, FKW 114, Ucon 114, Ledon 114, Isotron 114, Propellant 114, Halocarbon 114, Halon 242, Fluorane 114, 1,2-Dichloro-1,1,2,2-tetrafluoroethane, 1,1,2,2-Tetrafluoro-1,2-dichloroethane, 1,2-Dichlorotetrafluoroethane, sym-Dichlorotetrafluoroethane, s-Dichlorotetrafluoroethane, Ethane 1,2-dichloro-1,1,2,2-tetrafluoro-, Ethane 1,2-dichlorotetrafluoro-, Dichlorotetrafluoroethane, Tetrachlorodifluoroethane, CClF2CClF2, ClF2C-CClF2, CAS 76-14-2, EC 200-937-7, PubChem CID 6429, RTECS KI1101000, Class I Ozone-Depleting Substance, Fully Halogenated Chlorofluorocarbon, CFC Refrigerant, Historical Aerosol Propellant, Historical Centrifugal-Chiller Refrigerant, Historical Fire-Suppression Agent, Historical Foam-Blowing Agent, Historical Dielectric Fluid

APPLICATIONS

Cryofluorane was historically used as a refrigerant.
Cryofluorane was historically designated Refrigerant R-114.
Cryofluorane was historically used in mechanical vapor-compression refrigeration systems.
Cryofluorane was historically selected for systems requiring a comparatively high-boiling chlorofluorocarbon refrigerant.

Cryofluorane was historically used in centrifugal refrigeration compressors.
Cryofluorane was historically used in selected large refrigeration machines.
Cryofluorane was historically used in specialized chillers and cooling equipment.
Cryofluorane was historically used where its nonflammability and chemical stability were important design characteristics.

Cryofluorane was historically used in industrial cooling systems.
Cryofluorane was historically used as a process coolant.
Cryofluorane was historically used as a heat-transfer medium in specialized installations.
Cryofluorane was historically circulated in closed systems designed for liquefied refrigerant service.

Cryofluorane was historically used in special air-conditioning equipment.
Cryofluorane was historically used in selected heat-pump systems.
Cryofluorane was historically used in cooling loops requiring operating characteristics different from those of CFC-11 or CFC-12.
Cryofluorane legacy equipment may now require conversion, retirement, or servicing with lawfully recovered refrigerant.

Cryofluorane may remain present in old refrigeration equipment.
Cryofluorane may remain present in historical industrial cooling installations.
Cryofluorane may remain present in stored cylinders recovered from decommissioned equipment.
Cryofluorane must be recovered rather than deliberately released during maintenance or disposal.

Cryofluorane may be reclaimed for lawful servicing of compatible legacy equipment where regulations permit.
Cryofluorane may be recycled from existing systems using approved refrigerant-recovery equipment.
Cryofluorane may be transferred to an authorized reclamation facility for purification and analysis.
Cryofluorane reclaimed material must meet the applicable purity and regulatory requirements before reuse.

Cryofluorane was historically used as an aerosol propellant.
Cryofluorane was historically used alone or in propellant mixtures.
Cryofluorane was historically used to create pressure and atomization in pressurized dispensers.
Cryofluorane nonessential aerosol uses were discontinued because of ozone-layer protection requirements.

Cryofluorane was historically used in pharmaceutical aerosol systems.
Cryofluorane was historically used as a propellant component in some metered-dose inhalers.
Cryofluorane was historically used in combination with other CFC propellants.
Cryofluorane pharmaceutical propellant use was progressively replaced by non-CFC technologies.

Cryofluorane was historically used in epinephrine inhaler manufacture under essential-use arrangements.
Cryofluorane essential-use production allowances were limited and specifically regulated.
Cryofluorane should not be regarded as a generally available pharmaceutical propellant.
Cryofluorane is not an active pharmaceutical ingredient or inhaled anesthetic.

Cryofluorane was historically used in topical cooling aerosols.
Cryofluorane was historically used in cold-spray and freezing applications.
Cryofluorane was historically marketed under names associated with refrigeration and localized cooling.
Cryofluorane direct skin application can cause frostbite and is not appropriate outside an authorized formulated product.

Cryofluorane was historically used in dental cold-testing products.
Cryofluorane was historically used to cool applicators used in dental pulp-vitality assessment.
Cryofluorane was replaced in many dental products by non-ozone-depleting refrigerants.
Cryofluorane-containing historical dental cylinders require controlled recovery and disposal.

Cryofluorane was historically used in aerosol tire-inflation products.
Cryofluorane was historically blended with other CFCs in pressurized inflator formulations.
Cryofluorane was historically used in small refrigeration-system refill aerosols.
Cryofluorane use in such nonessential pressurized products is now restricted or prohibited.

Cryofluorane was historically used as a foam-blowing agent.
Cryofluorane was historically used to generate cellular structures in selected polymer foams.
Cryofluorane was historically incorporated into processes where vaporization created gas-filled cells.
Cryofluorane foam-blowing use was phased out because of ozone depletion.

Cryofluorane was historically used in specialized insulation-foam development.
Cryofluorane was historically evaluated for rigid and flexible foam processing.
Cryofluorane was historically selected where low flammability of the blowing agent was important.
Cryofluorane-containing old foam systems may continue to release trapped CFC during demolition or disposal.

Cryofluorane was historically used as a solvent.
Cryofluorane was historically used in specialized cleaning and degreasing processes.
Cryofluorane was historically used to dissolve or remove compatible oils and processing residues.
Cryofluorane solvent use was limited by its low boiling point and environmental impact.

Cryofluorane was historically used in precision-cleaning research.
Cryofluorane was historically evaluated for cleaning components requiring a nonflammable volatile medium.
Cryofluorane was historically used in closed vapor or liquid cleaning equipment.
Cryofluorane should not be introduced into new solvent-cleaning processes.

Cryofluorane was historically used as a degreasing agent.
Cryofluorane was historically used for selected metal and electrical components.
Cryofluorane was historically used where rapid evaporation and low residue were required.
Cryofluorane degreasing applications have been replaced by alternative solvents and aqueous processes.

Cryofluorane was historically used as a dielectric fluid.
Cryofluorane was historically used in specialized electrical and electronic equipment.
Cryofluorane was historically selected because the molecule is electrically nonconductive and chemically stable.
Cryofluorane dielectric applications require recovery from obsolete equipment rather than atmospheric venting.

Cryofluorane was historically used in electrical-insulation research.
Cryofluorane was historically used in equipment combining cooling and dielectric functions.
Cryofluorane was historically evaluated in high-voltage or electronic thermal-management systems.
Cryofluorane has been replaced in new designs by substances and technologies with lower environmental impact.

Cryofluorane was historically used as a fire-extinguishing material.
Cryofluorane was historically used because it is nonflammable.
Cryofluorane was historically evaluated for suppression of selected fires in enclosed or specialized environments.
Cryofluorane fire-suppression applications were discontinued or restricted because of ozone depletion and occupational-exposure concerns.

Cryofluorane was historically used as a component in specialized fire-control systems.
Cryofluorane was historically referred to as Halon 242 in some records.
Cryofluorane was historically used where residue-free extinguishing behavior was desirable.
Cryofluorane should not be substituted into modern fire-suppression systems without legal and engineering authorization.

Cryofluorane was historically used as a resin-processing aid.
Cryofluorane was historically used in the manufacture or processing of selected fluorinated and polymeric materials.
Cryofluorane was historically used as a volatile process medium.
Cryofluorane process use is now subject to controlled-substance rules and approved process-agent provisions.

Cryofluorane may be used as a chemical feedstock only under applicable controlled-substance regulations.
Cryofluorane may be transformed chemically into substances that are not ozone-depleting.
Cryofluorane transformation operations require reporting, containment, and emission controls.
Cryofluorane transformed in this manner must be chemically consumed rather than merely transferred into another mixture.

Cryofluorane may be used in narrowly defined laboratory and analytical procedures under applicable exemptions.
Cryofluorane laboratory use must qualify under current ozone-depleting-substance rules.
Cryofluorane laboratory purchases require appropriate documentation and recordkeeping.
Cryofluorane laboratory emissions must be minimized and recovered where technically feasible.

Cryofluorane is used as an analytical reference standard.
Cryofluorane is used to develop gas-chromatography methods.
Cryofluorane is used in mass-spectrometry identification and calibration research.
Cryofluorane is used in infrared-spectroscopy and atmospheric-analysis studies.

Cryofluorane is used in refrigerant-identification laboratories.
Cryofluorane is used to verify analytical separation from other CFCs and refrigerants.
Cryofluorane is used to calibrate instruments that measure refrigerant composition.
Cryofluorane reference standards must be stored and used in closed gas-handling systems.

Cryofluorane is used in environmental-monitoring research.
Cryofluorane is used as a target analyte in atmospheric CFC measurements.
Cryofluorane is used to study long-lived halocarbon concentrations.
Cryofluorane is used to evaluate historical and current emissions of ozone-depleting substances.

Cryofluorane is used in stratospheric-chemistry research.
Cryofluorane is used to study transport of stable CFC molecules into the upper atmosphere.
Cryofluorane is used to investigate chlorine release following ultraviolet degradation.
Cryofluorane is used to model effects of CFC emissions on stratospheric ozone.

Cryofluorane is used in climate research.
Cryofluorane is used as a long-lived greenhouse-gas analyte.
Cryofluorane is used to compare radiative effects of historical refrigerants.
Cryofluorane has been assigned a representative 100-year global-warming potential near 10,000 in older EPA reference data.

Cryofluorane is used in ozone-depletion-potential research.
Cryofluorane is used as a Class I controlled CFC with a Montreal Protocol ozone-depletion potential of 1.
Cryofluorane is used in environmental models comparing CFC emissions and ozone-layer effects.
Cryofluorane release prevention is important because of its high atmospheric stability.

Cryofluorane is used in thermophysical-property research.
Cryofluorane is used to evaluate vapor pressure, phase behavior, enthalpy, and heat capacity.
Cryofluorane is used in refrigerant-equation-of-state development.
Cryofluorane is used to validate historical refrigeration-system calculations.

Cryofluorane is used in gas-phase thermochemistry research.
Cryofluorane is used in condensed-phase thermochemistry studies.
Cryofluorane is used in Henry’s-law and gas-solubility measurements.
Cryofluorane is used in gas-phase ionization and reaction-kinetics research.

Cryofluorane is used in occupational-exposure method development.
Cryofluorane is used to validate air-sampling and gas-analysis procedures.
Cryofluorane is included in NIOSH Method 1018 for selected halogenated hydrocarbons.
Cryofluorane workplace measurements are compared with the applicable time-weighted exposure limit.

Cryofluorane is used in toxicology research involving halogenated hydrocarbons.
Cryofluorane is used to investigate acute inhalation effects.
Cryofluorane is used to study cardiac sensitization and arrhythmia risk.
Cryofluorane is used only in appropriately contained experimental systems.

Cryofluorane is used in asphyxiation-hazard research.
Cryofluorane is used to model oxygen displacement by dense refrigerant gases.
Cryofluorane is used in confined-space ventilation studies.
Cryofluorane is used to evaluate gas-detection and oxygen-monitoring procedures.

Cryofluorane is used in refrigerant-recovery training with controlled legacy equipment.
Cryofluorane is used to demonstrate recovery of Class I refrigerants without venting.
Cryofluorane is used to evaluate leak-tight transfer and cylinder-management procedures.
Cryofluorane training use must comply with refrigerant-handling and environmental regulations.

Cryofluorane is used in reclamation facilities as a recovered material requiring analysis.
Cryofluorane is separated from mixed refrigerant streams where technically feasible.
Cryofluorane is tested for identity, moisture, acidity, noncondensable gases, and other contaminants.
Cryofluorane is reused, transformed, or destroyed according to its analytical quality and legal status.

Cryofluorane is used as a target compound in refrigerant-bank inventories.
Cryofluorane is included when estimating CFC quantities remaining in old equipment.
Cryofluorane is included in planning for controlled recovery and destruction.
Cryofluorane inventories support prevention of future ozone-depleting emissions.

Cryofluorane is used in destruction-efficiency testing.
Cryofluorane is used to assess technologies intended to destroy controlled CFCs.
Cryofluorane destruction requires verified conversion into stable non-ozone-depleting products.
Cryofluorane destruction facilities must control hydrogen halides and other decomposition products.

Cryofluorane is used in transformation-process verification.
Cryofluorane is used to demonstrate conversion into useful non-ODS chemical products.
Cryofluorane transformation requires complete accounting of feed, product, emissions, and residues.
Cryofluorane transformation does not permit uncontrolled atmospheric release.

Cryofluorane is not recommended for new refrigeration designs.
Cryofluorane is not recommended for new aerosol formulations.
Cryofluorane is not recommended for new solvent, foam, fire-suppression, or dielectric applications.
Cryofluorane alternatives must be selected through current safety, climate, regulatory, and engineering assessments.

DESCRIPTION

Cryofluorane is the historical or regulatory name for CFC-114.
Cryofluorane is chemically 1,2-dichloro-1,1,2,2-tetrafluoroethane.
Cryofluorane is a fully halogenated chlorofluorocarbon.
Cryofluorane contains two carbon atoms, two chlorine atoms, and four fluorine atoms.

Cryofluorane has the molecular formula C2Cl2F4.
Cryofluorane has a molecular weight of approximately 170.92 g/mol.
Cryofluorane has CAS number 76-14-2.
Cryofluorane has EC number 200-937-7.

Cryofluorane has the condensed structural formula CClF2CClF2.
Cryofluorane has the InChIKey DDMOUSALMHHKOS-UHFFFAOYSA-N.
Cryofluorane has a symmetrical ethane-based molecular structure.
Cryofluorane contains no hydrogen atoms.

Cryofluorane should not be confused with cryoflurane as a hypothetical anesthetic-style name.
Cryofluorane is not isoflurane, sevoflurane, desflurane, or another modern volatile anesthetic.
Cryofluorane is principally an historical refrigerant and aerosol propellant.
Cryofluorane’s name reflects cooling and fluorocarbon use rather than anesthetic pharmacology.

Cryofluorane is a colorless gas under ordinary room conditions.
Cryofluorane has a faint ether-like odor at high concentrations.
Cryofluorane is a liquid below approximately 38°F or 3.3–3.6°C at atmospheric pressure.
Cryofluorane is shipped as a liquefied compressed gas.

Cryofluorane has a boiling point near 38°F.
Cryofluorane has a freezing point near −137°F.
Cryofluorane has a representative water solubility of approximately 0.01%.
Cryofluorane has a vapor pressure of approximately 1.9 atmospheres at 70°F.

Cryofluorane has a relative gas density of approximately 5.93 compared with air.
Cryofluorane vapor can collect in low areas.
Cryofluorane can displace breathable air in pits, tanks, basements, and confined spaces.
Cryofluorane releases may create an asphyxiation hazard without producing a strong warning odor.

Cryofluorane is nonflammable under ordinary test conditions.
Cryofluorane has no applicable lower explosive limit.
Cryofluorane has no applicable upper explosive limit.
Cryofluorane cylinders can nevertheless rupture violently if heated or exposed to fire.

Cryofluorane has an ionization potential of approximately 12.20 eV.
Cryofluorane has low water solubility.
Cryofluorane has high chemical stability in the lower atmosphere.
Cryofluorane stability contributes both to useful refrigerant behavior and prolonged environmental persistence.

Cryofluorane is incompatible with chemically active metals.
Cryofluorane NIOSH incompatibility information includes sodium, potassium, and calcium.
Cryofluorane NIOSH incompatibility information also includes powdered aluminum, zinc, and magnesium.
Cryofluorane should also be separated from acids and acid fumes.

Cryofluorane can decompose when exposed to severe heat, flame, or reactive surfaces.
Cryofluorane thermal decomposition can generate toxic and corrosive halogen-containing fumes.
Cryofluorane should not be exposed deliberately to welding arcs, red-hot metal, or open flames.
Cryofluorane fire response requires supplied-air respiratory protection where decomposition products may be present.

Cryofluorane exposure occurs principally through inhalation.
Cryofluorane liquid exposure can occur through leaking cylinders, valves, hoses, and transfer connections.
Cryofluorane rapidly evaporating liquid can freeze exposed skin and eyes.
Cryofluorane contact with liquid therefore presents a cryogenic-type frostbite hazard.

Cryofluorane inhalation can irritate the respiratory system.
Cryofluorane high concentrations can cause oxygen-deficiency asphyxia.
Cryofluorane high concentrations can cause cardiac arrhythmias.
Cryofluorane severe exposure can result in cardiac arrest.

Cryofluorane target organs include the respiratory system.
Cryofluorane target organs include the cardiovascular system.
Cryofluorane exposure symptoms may develop rapidly after a major leak.
Cryofluorane-exposed persons require prompt removal from the contaminated atmosphere.

Cryofluorane has a NIOSH recommended exposure limit of 1,000 ppm as an eight-hour time-weighted average.
Cryofluorane has an OSHA permissible exposure limit of 1,000 ppm as a time-weighted average.
Cryofluorane has a conversion factor of approximately 6.99 mg/m³ per ppm.
Cryofluorane’s corresponding listed mass concentration is approximately 7,000 mg/m³.

Cryofluorane has a NIOSH immediately dangerous to life or health concentration of 15,000 ppm.
Cryofluorane unknown or potentially IDLH atmospheres require positive-pressure supplied breathing equipment.
Cryofluorane confined-space entry requires atmospheric testing and a formal entry procedure.
Cryofluorane air-purifying respirators do not supply oxygen and cannot protect against oxygen deficiency.

Cryofluorane is a Class I ozone-depleting substance.
Cryofluorane has a Montreal Protocol ozone-depletion potential of 1.
Cryofluorane undergoes limited degradation in the lower atmosphere.
Cryofluorane can reach the stratosphere, where ultraviolet radiation ultimately releases ozone-depleting chlorine.

Cryofluorane has a very long atmospheric lifetime.
Cryofluorane older EPA reference data report an atmospheric lifetime of approximately 190 years.
Cryofluorane older EPA reference data report a 100-year global-warming potential near 10,000.
Cryofluorane emissions therefore create both ozone-layer and climate concerns.

Cryofluorane production and import for ordinary uses were phased out in the United States.
Cryofluorane belongs to the CFC group covered by the January 1, 1996 Class I phaseout.
Cryofluorane limited exemptions may apply to qualifying laboratory, analytical, transformation, or other specifically authorized uses.
Cryofluorane regulatory status must be checked in the destination country before purchase, import, export, use, or disposal.

Cryofluorane existing stocks should be recovered, recycled, reclaimed, transformed, or destroyed.
Cryofluorane should not be deliberately vented during maintenance or disposal.
Cryofluorane recovered from obsolete equipment must remain in approved pressure containers.
Cryofluorane cylinder and refrigerant-bank management should preserve traceability.

Cryofluorane technical specifications can differ between virgin historical material and reclaimed refrigerant.
Cryofluorane reclaimed material may contain moisture, air, oil, acids, and other refrigerants.
Cryofluorane identity cannot be confirmed reliably from cylinder markings alone.
Cryofluorane recovered material requires analytical confirmation before reuse or destruction.

Cryofluorane container pressure changes significantly with temperature.
Cryofluorane cylinders require protection from excessive heat.
Cryofluorane liquid expansion can create dangerous hydraulic pressure in completely filled isolated sections.
Cryofluorane systems require correctly rated pressure-relief devices.

Cryofluorane leaks can produce cold fog or condensation.
Cryofluorane visible fog may result from cooling and condensation of atmospheric moisture.
Cryofluorane gas itself can remain difficult to see.
Cryofluorane leak response should rely on detection equipment and oxygen monitoring rather than visibility or odor.

Cryofluorane may be detected using suitable refrigerant leak detectors.
Cryofluorane may be measured by gas chromatography.
Cryofluorane may be measured using NIOSH Method 1018.
Cryofluorane analytical procedures require gas-tight sampling and calibrated standards.

Cryofluorane is not normally transported as an unpressurized room-temperature liquid.
Cryofluorane is transported in pressure-rated containers as a liquefied gas.
Cryofluorane NIOSH information lists DOT identification number 1958.
Cryofluorane exact shipping name, hazard class, labels, and packing requirements must be taken from current transport regulations and the product SDS.

Cryofluorane grade selection is now principally a question of recovered-material quality and lawful intended use.
Cryofluorane analytical-grade standards require controlled purity and traceability.
Cryofluorane reclaimed refrigerant requires specification testing before legacy-equipment service.
Cryofluorane material intended for destruction requires secure identification and inventory documentation.

PROPERTIES

Chemical Name: 1,2-Dichloro-1,1,2,2-tetrafluoroethane
Product Name: Cryofluorane
Common Refrigerant Name: CFC-114
Refrigerant Designation: R-114
Chemical Family: Chlorofluorocarbons
Regulatory ODS Class: Class I ozone-depleting substance
CAS Number: 76-14-2
EC Number: 200-937-7
PubChem CID: 6429
RTECS Number: KI1101000
NIST InChIKey: DDMOUSALMHHKOS-UHFFFAOYSA-N
Molecular Formula: C2Cl2F4
Condensed Structural Formula: CClF2CClF2
Molecular Weight: 170.92 g/mol
Physical State at Room Temperature: Gas
Transport Form: Liquefied compressed gas
Appearance: Colorless
Odor: Faint ether-like odor at high concentrations
Representative Boiling Point: Approximately 38°F or 3.3–3.6°C
Representative Freezing Point: Approximately −137°F or −94°C
Representative Water Solubility: Approximately 0.01%
Representative Vapor Pressure: Approximately 1.9 atm at 70°F
Relative Gas Density: Approximately 5.93
Air Behavior: Heavier than air and capable of collecting in low areas
Ionization Potential: Approximately 12.20 eV
Flammability: Nonflammable under ordinary conditions
Flash Point: Not applicable
Lower Explosive Limit: Not applicable
Upper Explosive Limit: Not applicable
Primary Historical Function: Refrigerant
Other Historical Functions: Aerosol propellant, solvent, fire-suppression agent, foam-blowing agent, dielectric fluid, and heat-transfer medium
Principal Historical Refrigeration Application: Centrifugal and specialized refrigeration equipment
Current General Use Status: Phased out for ordinary new production and import
Current Potential Uses: Lawful legacy-equipment service using recovered material, qualifying laboratory and analytical use, chemical transformation, reclamation, and destruction
Montreal Protocol Ozone-Depletion Potential: 1
Representative Atmospheric Lifetime: Approximately 190 years in older EPA data
Representative 100-Year Global-Warming Potential: Approximately 10,000 in older EPA data
NIOSH REL: 1,000 ppm TWA
OSHA PEL: 1,000 ppm TWA
Mass Exposure Equivalent: Approximately 7,000 mg/m³
NIOSH IDLH: 15,000 ppm
Conversion Factor: 1 ppm equals approximately 6.99 mg/m³
Primary Exposure Route: Inhalation
Liquid Exposure Routes: Skin and eye contact
Primary Acute Hazards: Respiratory irritation, asphyxia, cardiac arrhythmia, cardiac arrest, and frostbite
Target Organs: Respiratory and cardiovascular systems
Thermal-Decomposition Hazard: Toxic and corrosive halogen-containing fumes
Incompatible Materials: Sodium, potassium, calcium, powdered aluminum, zinc, magnesium, acids, and acid fumes
DOT Identification Listed by NIOSH: 1958
Transport Classification: Liquefied gas; exact current classification is jurisdiction dependent
Environmental Hazard: Ozone depletion and long-term greenhouse effect
Disposal Requirement: Authorized recovery, reclamation, transformation, or destruction
Storage Conditions: Cool, dry, ventilated storage in approved pressure containers
Storage Protection: Protect from heat, fire, physical damage, incompatible materials, and unauthorized release
Shelf Life: Container integrity, purity, corrosion, storage conditions, and supplier dependent
Regulatory Suitability: Use, possession, production, import, export, reclamation, transport, and disposal are jurisdiction dependent

FIRST AID

Inhalation:
Immediately move the affected person to fresh air without exposing rescuers to the contaminated atmosphere.
Provide respiratory support or oxygen through trained personnel and obtain emergency medical attention after significant exposure.

Skin Contact with Liquid:
Remove contaminated clothing only when it is not frozen to the skin.
Warm the frostbitten area gradually with lukewarm water and obtain prompt medical attention.

Eye Contact with Liquid:
Immediately flush the eyes with lukewarm water for at least 15 minutes.
Do not rub the eyes and obtain urgent ophthalmic or emergency medical evaluation.

Ingestion:
Ingestion is unlikely because the product is gaseous at ordinary temperatures.
Obtain immediate medical attention if liquefied material has entered the mouth or digestive tract.

Note to Physicians:
Treat symptomatically and provide respiratory and cardiovascular support.
Monitor cardiac rhythm because significant inhalation exposure can produce arrhythmias or cardiac arrest.

HANDLING AND STORAGE

Handling:
Use closed refrigerant-recovery, transfer, and charging equipment.
Do not deliberately vent Cryofluorane into the atmosphere.

Engineering Controls:
Provide effective general ventilation and local extraction at valves, hoses, recovery machines, sampling points, and cylinder connections.
Use oxygen monitoring in enclosed or below-grade areas where a large release could displace air.

Personal Protection:
Wear safety goggles or a face shield and thermally insulated chemical-resistant gloves during liquid transfer.
Wear protective clothing capable of limiting contact with rapidly evaporating liquid.

Respiratory Protection:
Use positive-pressure self-contained breathing apparatus for emergency response, unknown concentrations, oxygen-deficient atmospheres, or IDLH conditions.
Do not rely on air-purifying respirators where oxygen displacement is possible.

Cylinder Handling:
Keep cylinders upright, secured, correctly labeled, and protected from impact.
Use valves, hoses, gauges, and recovery equipment rated for the refrigerant pressure.

Storage:
Store in an approved cool and well-ventilated compressed-gas area.
Protect cylinders from direct sunlight, fire, excessive heat, corrosion, physical damage, and incompatible reactive materials.

Fire and Heat:
Cool exposed cylinders from a protected position when this can be done safely.
Withdraw immediately if a cylinder becomes discolored, deformed, or exposed to uncontrolled fire.

Spill and Leak Procedures:
Evacuate unnecessary personnel and isolate low-lying or enclosed areas.
Ventilate the area, monitor oxygen, and stop the release only when this can be done safely.

Environmental Precautions:
Recover leaking material with approved equipment whenever technically possible.
Do not discharge Cryofluorane into drains, water, soil, or the atmosphere.

Maintenance:
Recover refrigerant before opening, cutting, welding, dismantling, or disposing of equipment.
Verify that equipment has been evacuated and tested before hot work.

Disposal:
Send recovered Cryofluorane to an authorized refrigerant reclaimer, transformation facility, or approved destruction facility.
Maintain records required for controlled ozone-depleting substances.

Handling Precautions:
Do not use Cryofluorane in a new product merely because old stock is available.
Follow the current safety data sheet, pressure-equipment rules, refrigerant regulations, Montreal Protocol controls, and national ozone-layer legislation.