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Cyclamic Acid and its Na Salts are also used in nutraceutical and dietary supplement products.
Cyclamic Acid and its Na Salts are widely used in many countries, although regulatory approval differs internationally.
Cyclamic Acid and its Na Salts are artificial sweeteners that are 30 to 50 times sweeter than regular sugar.
Cyclamic Acid
CAS Number: 100-88-9
EC Number: 202-898-1
Molecular Formula: C6H13NO3S
Molecular Weight: 179.24 g/mol
Sodium Cyclamate (Cyclamic Acid' Na salts)
CAS Number: 139-05-9
EC Number: 205-348-9
Molecular Formula: C6H12NNaO3S
Molecular Weight: 201.22 g/mol
SYNONYMS:
Cyclamic Acid Synonyms
Cyclamic Acid, Cyclohexylsulfamic Acid, Cyclohexanesulfamic Acid, Cyclamate Acid, Sulfamic Acid Cyclohexyl Ester, Cyclohexanesulfamic acid, Hexamic acid, Cyclohexylsulfamic acid, Sulfamic acid, cyclohexyl-, Cyclohexylamidosulfuric acid, Cyclohexylaminesulfonic acid, N-Cyclohexylsulfamic acid, Sucaryl, Sucaryl acid, Zyklamat, Cyclohexanesulphamic acid, Cyclohexylamidosulphuric acid, Cyclohexylaminesulphonic acid, Cyclohexylsulphamic acid, N-Cyclohexylsulphamic acid, Cyclamate, NSC 220327, Polycat 200, Sulfamic acid, N-cyclohexyl-, Cyclohexylsulfamic acid, Cyclamic Acid, Cyclohexylsulfamic Acid, Cyclohexanesulfamic Acid, Cyclohexylaminosulfonic Acid, N-Cyclohexylsulfamic Acid, Cyclamate Acid, Sulfamic Acid Cyclohexyl Ester, N-Cyclohexylsulfamic Acid, Cyclohexanesulfamic Acid, Cyclohexylamidosulfuric Acid, Cyclohexylaminesulfonic Acid, Hexamic Acid, NSC 220327, Polycat 200, Cyclamate (free acid)
Sodium Cyclamate (Cyclamic Acid' Na salts) Synonyms
Sodium Cyclamate, Sodium Cyclohexylsulfamate, Cyclamate Sodium, Sodium N-Cyclohexylsulfamate, Sodium Cyclohexanesulfamate, E952, INS 952, Cyclohexylsulfamic Acid Monosodium Salt, Acofarinas, Assugrin, Asugryn, Azucrona, Cyclamate Sodium, Cyclohexylsulfamate Sodium, Cyclohexylsulfamic Acid Sodium Salt, Dulzor-Etas, Duplo-Sacarin, Hachi-Sugar, Ibiosuc, N-Cyclohexylsulfamic Acid Sodium Salt, Natreen, Nutter, Sodium Cyclamate, Sodium cyclohexanesulfamate, Sodium cyclohexylaminesulfonate, Sodium Cyclohexylsulfamate, Sodium sucaryl, Sucaryl sodium, Sucrum 7, Suessette, Suestamin, Sugarin, Sugaron, Sulfamic acid, cyclohexyl-, monosodium salt (9CI), Acofarinas, Assugrin, Asugryn, Azucrona, Cyclamate sodium, Cyclohexylsulfamate sodium, Cyclohexylsulfamic acid sodium salt, Dulzor-Etas, Duplo-Sacarin, Hachi-Sugar, Ibiosuc, N-Cyclohexylsulfamic acid sodium salt, Natreen, Nutter, Sodium cyclamate, Sodium cyclohexanesulfamate, Sodium cyclohexylaminesulfonate, Sodium cyclohexylsulfamate, Sodium sucaryl, Sucaryl sodium, Sucrum 7, Suessette, Suestamin, Sugarin, Sugaron, Cyclohexanesulfamic acid, monosodium salt (8CI), aminocyclohexylsulfonic acid, sodium salt, cyclamate sodium, cyclamate, sodium, Cyclamate, Sodium Salt, cyclamic acid sodium salt, cyclohexane sulfamic acid monosodium salt, cyclohexanesulfamic acid sodium salt, cyclohexanesulfamic acid, monosodium salt, cyclohexanesulfamic acid, sodium salt, cyclohexanesulphamic acid, monosodium salt, cyclohexyl sulfamic acid sodium salt, cyclohexylsulfamic acid monosodium salt, cyclohexylsulfamic acid sodium salt, N- cyclohexylsulfamic acid sodium salt, cyclohexylsulfamic acid, sodium salt, cyclohexylsulphamate sodium, cyclohexylsulphamic acid, monosodium salt, hachi-sugar, sodium cyclohexanesulfamate, mono sodium cyclohexyl sulfamate, sodium cyclohexylsulfamate, mono sodium cyclohexylsulfamate, sodium cyclohexylsulphamidate, sodium N-cyclohexylsulfamate, sodium sucaryl, sodiumcyclamate, sucaryl acid sodium salt, sucaryl sodium, sucrum 7, sulfamic acid, cyclohexyl-, monosodium salt, sulfamic acid, cylclohexyl-, monosodium salt, sulfamic acid, N-cyclohexyl-, sodium salt (1:1),
Cyclamic Acid and its Na Salts, with the CAS number 139-05-9, are synthetic sweeteners that are approximately 30 to 50 times sweeter than sucrose (table sugar).
Cyclamic Acid and its Na Salts are a white, crystalline powder that is highly soluble in water, making it suitable for various food and beverage applications.
Cyclamic Acid and its Na Salts are often used in combination with other sweeteners to enhance sweetness and improve flavor profiles.
Cyclamic Acid and its Na Salts are stable under heat and do not undergo significant degradation during cooking or baking, which makes it a popular choice for processed foods.
Cyclamic Acid and its Na Salts are also low in calories, making them appealing for use in diet and low-calorie products.
As with any food additive, Cyclamic Acid and its Na Salts are important to adhere to regulatory guidelines regarding its use and consumption.
Cyclamic Acid and its Na Salts are often blended with saccharin at ratios such as 10:1 because the combination creates sweetness synergy and improves sensory quality.
Cyclamic Acid and its Na Salts became highly popular in low-calorie beverage systems and tabletop sweeteners.
Cyclamic Acid and its Na Salts are highly effective in acidic food matrices because they maintain sweetness stability over time.
Cyclamic Acid and its Na Salts' heat resistance also allows use in thermally processed foods where some other sweeteners may degrade.
Cyclamic Acid and its Na Salts remain important in industrial sweetener technology due to its cost efficiency, functionality, and compatibility with large-scale beverage manufacturing systems.
Cyclamic acid itself is the acidic form, while Cyclamic Acid and its Na Salts are the sodium salt most commonly used commercially because of their improved water solubility and stability.
Cyclamic Acid and its Na Salts provide sweetness with very low caloric value and are frequently combined with other sweeteners such as saccharin or steviol glycosides to improve taste profiles and sweetness synergy.
Cyclamic Acid and its Na Salts are approximately 30–50 times sweeter than sucrose, depending on formulation and application.
Cyclamic Acid and its Na Salts are known for having a relatively clean sweetness profile with less bitterness compared with some other artificial sweeteners.
USES and APPLICATIONS of CYCLAMIC ACID and ITS Na SALTS:
Cyclamic Acid and its Na Salts are used worldwide as a sweetener in a wide selection of products.
Thanks to its heat resistance and flavor-enhancing properties, Cyclamic Acid and its Na Salts are suitable for, among others: Soft drinks and sports drinks; Sugar-free jams, desserts, and chocolate; Fermentable dairy products; Chewing gum, candy, and tablets; Nutritional supplements and diet products; Pharmaceutical formulations such as syrups.
Cyclamic Acid and its Na Salts are extensively used in low-calorie and sugar-free food products.
Cyclamic Acid and its Na Salts are commonly found in carbonated beverages, flavored drinks, tabletop sweeteners, desserts, confectionery, chewing gum, jams, jellies, canned fruits, bakery products, dairy products, and processed foods designed for calorie reduction.
Cyclamic Acid and its Na Salts are synthetic high-intensity sweeteners widely used in the food, beverage, pharmaceutical, and personal care industries.
In the pharmaceutical industry, Cyclamic Acid and its Na Salts is used in syrups, chewable tablets, vitamin supplements, cough medicines, and oral liquid formulations to improve palatability and mask unpleasant tastes.
Cyclamic Acid and its Na Salts are also used in nutraceutical and dietary supplement products.
Cyclamic Acid and its Na Salts are widely used in many countries, although regulatory approval differs internationally.
Cyclamic Acid and its Na Salts are artificial sweeteners that are 30 to 50 times sweeter than regular sugar.
Cyclamic Acid and its Na Salts contain no calories and are widely used in the food industry, especially in low-calorie and sugar-free products such as soft drinks, desserts, dairy, and tablets.
Cyclamic Acid and its Na Salts are the sodium salt form of cyclamic acid and are widely applied due to their sugar-like taste, good solubility, and high stability when heated or stored for extended periods.
In personal care and oral hygiene products, Cyclamic Acid and its Na Salts may be incorporated into toothpaste, mouthwash, and flavored oral products due to their sweetening capability and stability.
Industrial food manufacturers frequently use Cyclamic Acid and its Na Salts in combination with saccharin because the blend produces a more sugar-like sweetness profile and reduces bitter or metallic aftertastes.
Cyclamic Acid and its Na Salts are especially useful in products requiring heat processing because it retains sweetness during pasteurization and baking.
-Cosmetics uses of Cyclamic Acid and its Na Salts:
Fragrance.
Cyclamic Acid and its Na Salts play a decisive and important role in the formulation of cosmetic products, as it provides the possibility of enhancing, masking, or adding fragrance to the final product, increasing its marketability.
Cyclamic Acid and its Na Salts are able to create a perceptible pleasant odour, masking a bad smell.
The consumer always expects to find a pleasant or distinctive scent in a cosmetic product.
WHAT CYCLAMIC ACID and ITS Na SALTS ARE USED FOR AND WHERE
Cyclamic Acid and its Na Salts are commonly used in foods and beverages as a sugar substitute to reduce calorie intake.
Cyclamic Acid and its Na Salts are particularly popular in diet and diabetic products.
However, the use of Cyclamic Acid and its Na Salts is subject to regulation and restrictions in some countries due to safety concerns.
Food
Cyclamic Acid and its Na Salts are used as a non-nutritive sweetener with a sweetening capacity of 30 to 50 times more than sugar in a wide variety of food products: Bakery products, Desserts, Cakes, Jellies, Confectionery, Biscuits, Compound condiments, Table sweeteners, Fruit preserves, Jams and marmalades, Chewing gum, Pickled vegetables, Preserved fruit, etc.
Cyclamic Acid and its Na Salts are labelled with the number E959 in the list of European food additives.
BENEFITS of CYCLAMIC ACID and ITS Na SALTS:
Low-calorie sweetening agent
Suitable for sugar-reduced formulations
Good thermal stability
Stable in acidic beverages
Economical compared with many alternative sweeteners
Synergistic effect with other sweeteners
Clean sweetness profile
Long shelf life
Effective in pharmaceutical flavor masking
Suitable for diabetic-oriented products
Good water solubility for beverage systems
CHARACTERISTICS of CYCLAMIC ACID and ITS Na SALTS:
Cyclamic Acid and its Na Salts are valued because they provide sweetness with minimal caloric contribution.
Cyclamic Acid and its Na Salts have a smoother and less metallic taste compared with saccharin, making it suitable for blended sweetener systems.
Cyclamic Acid and its Na Salts exhibit excellent heat stability and are appropriate for cooking, pasteurization, baking, and long shelf-life products.
Cyclamic Acid and its Na Salts demonstrate strong synergistic effects when combined with other sweeteners.
This allows manufacturers to reduce the concentration of individual sweeteners while achieving balanced sweetness profiles and masking undesirable aftertastes.
Cyclamic Acid and its Na Salts are economically attractive because they are inexpensive compared with many newer high-intensity sweeteners and maintain stable sweetness in acidic beverages and processed foods.
CYCLAMIC ACID AND ITS NA SALTS FOR DIABETICS AND LOW-CALORIE CONCEPTS:
An important advantage of Cyclamic Acid and its Na Salts is that it does not affect blood sugar levels and are therefore safe for people with diabetes.
The body absorbs only a limited amount of the substance and excretes most of it unchanged via urine or feces.
As a result, Cyclamic Acid and its Na Salts provide no calories and causes no insulin spikes.
PRODUCTION of CYCLAMIC ACID and ITS Na SALTS:
Cyclamic Acid and its Na Salts are produced by chemical synthesis with cyclohexane and sulphamic acid as raw materials.
The name describes the structure of the molecule
Sodium indicates the presence of sodium ions (Na).
In the context of sweeteners, sodium is used to form salts with organic compounds.
Cyclamate is an organic compound known for its sweetening properties that is many times sweeter than table sugar (sucrose) but has a lower calorie contribution.
Raw materials used in production.
Cyclohexane - Cyclohexane is a cyclic hydrocarbon used as a raw material in the synthesis of Cyclamic Acid and its Na Salts.
Sulfamic Acid - Sulfamic acid is a chemical substance used in the synthesis reaction to produce Cyclamic Acid and its Na Salts.
Step-by-step summary of industrial chemical synthesis process
Preparation of Raw Materials - Cyclohexane and sulfamic acid are prepared and purified as raw materials.
Synthesis of Cyclamic Acid and its Na Salts - Cyclohexane and sulfamic acid are reacted in a controlled chemical reaction to produce Cyclamic Acid and its Na Salts.
This chemical reaction involves the formation of a bond between sulfamic acid and cyclohexane, creating the chemical structure of Cyclamic Acid and its Na Salts.
Crystallization and Purification - The resulting Cyclamic Acid and its Na Salts are crystallized and purified to remove impurities and obtain the final product.
Cyclamic Acid and its Na Salts are typically available in the form of white crystals or powder.
COMBINATION of CYCLAMIC ACID and ITS Na SALTS WITH OTHER SWEETENERS:
Cyclamic Acid and its Na Salts are often combined with sweeteners such as saccharin, sucralose, or acesulfame-K.
Not because Cyclamic Acid and its Na Salts' sweetness (30–50 times sweeter than sugar) is insufficient, but mainly to improve the taste profile.
These combinations create a sweetness and mouthfeel that are even closer to regular sugar, often without the bitter aftertaste that some sweeteners can have individually.
SAFETY AND REGULATION of CYCLAMIC ACID and ITS Na SALTS:
Cyclamic Acid and its Na Salts (E952) is approved for use in over 50 countries.
Cyclamic Acid and its Na Salts' safety has been extensively evaluated by independent scientific bodies such as the Scientific Committee on Food (SCF) and JECFA.
The acceptable daily intake (ADI) is set at 7 mg/kg body weight per day.
For a small group of people (7–11%) who partially convert cyclamate into cyclohexylamine, extra attention is required during formulation, but when the ADI is observed, its use is safe.
PHYSICAL and CHEMICAL PROPERTIES of CYCLAMIC ACID and ITS Na SALTS:
CYCLAMIC ACID
Appearance: White crystalline powder
Odor: Odorless
Taste: Sweet
Physical State: Solid
Solubility: Slightly soluble in water
Melting Point: Approximately 168–170°C
Density: Approximately 1.37 g/cm³
Hygroscopicity: Low
Stability: Stable under normal storage conditions
Chemical Class: Sulfamic acid derivative
Functional Groups:
Sulfamate group
Cyclohexyl ring
Acidity: Weak acid
Reactivity: Low under normal conditions
Volatility: Non-volatile
Flammability: Non-flammable under standard conditions
CAS Number: 100-88-9
EC Number: 202-898-1
Molecular Formula: C6H13NO3S
Molecular Weight: 179.24 g/mol
Sodium Cyclamate (Cyclamic Acid' Na salts)
Appearance: White crystalline powder or crystals
Odor: Odorless
Taste: Intensely sweet with clean flavor profile
Sweetness Intensity: Approximately 30–50 times sweeter than sucrose
Solubility: Highly soluble in water
Physical State: Solid
Bulk Density: Variable depending on grade
Thermal Stability: Good heat stability
pH Stability: Stable over broad pH ranges
Hygroscopicity: Slightly hygroscopic
Decomposition Temperature: Above normal food processing temperatures
Chemical Class: Sulfamate sweetener salt
Ionic Character: Sodium salt of cyclamic acid
Stability: Chemically stable in dry conditions
Compatibility: Compatible with many food ingredients
Synergistic Sweetening: Often used with saccharin and aspartame
Hydrolysis Resistance: Good resistance under moderate processing conditions
Oxidation Stability: Stable during standard manufacturing processes
ECHA EINECS - REACH Pre-Reg: 205-348-9
FDA UNII: 1I6F42RME1
Nikkaji Web: J813C
Beilstein Number: 4166868
MDL: MFCD00003827
Molecular Weight: 201.22100928
Formula: C6 H12 N Na O3 S
Appearance: white crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 0.979 (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)
Insoluble in: alcohol
CAS Number: 139-05-9
EC Number: 205-348-9
Molecular Formula: C6H12NNaO3S
Molecular Weight: 201.22 g/mol
FIRST AID MEASURES of CYCLAMIC ACID and ITS Na SALTS:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of CYCLAMIC ACID and ITS Na SALTS:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of CYCLAMIC ACID and ITS Na SALTS:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of CYCLAMIC ACID and ITS Na SALTS:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
HANDLING and STORAGE of CYCLAMIC ACID and ITS Na SALTS:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of CYCLAMIC ACID and ITS Na SALTS:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available:
