D-XYLOSE

D-Xylose is used in the D‑xylose absorption test to assess small‑intestinal mucosal absorption; reduced urinary excretion indicates malabsorption (e.g. celiac disease, bacterial overgrowth)
D-Xylose is used raw material for furfural production via acid‑catalyzed degradation of hemicellulose; furfural is a precursor for polymers and solvents
D-Xylose is used as a low‑calorie sweetener, especially for diabetics; contains ~2.4 kcal/g (about half of glucose)

CAS Number: 58-86-6
EC Number: 200-022-8
MDL number: MFCD00064360
Chemical Formula: C5H10O5
Molecular Weight: 150.13 g/mol

SYNONYMS:
D-Xylose, Wood Sugar, Xylo-aldose, (+)-Xylose, Xylo-Pentose, Aldopentose, d-(+)-Xylose, Beta-D-Xylose, D-xylose, xylose, D-xylopyranose, XYLOPYRANOSE, D-Xyl, xylopyranoside, d-xylopyranoside, XYL, Xyloside, (3R,4S,5R)-oxane-2,3,4,5-tetrol, 7261-26-9, Wood sugar, D-xylopentose, 10257-31-5, CHEBI:53455, 50855-32-8, Xylopyranose (6CI,7CI,8CI,9CI), Xylomed, DTXCID903745, DTXSID0023745, Xylo-Pfan, (3R,4S,5R)-tetrahydro-2H-pyran-2,3,4,5-tetrol, D(+)-XYLOSE, rel-(3R,4S,5R)-Tetrahydro-2H-pyran-2,3,4,5-tetraol, Xylose, pure, D-(+)-Xylose, >=99%, (3R,4S,5R)-Tetrahydro-2H-pyran-2,3,4,5-tetraol, D Xylose, xylo-pentose, BRN 1562108, AI3-19010, Xylose (USP), Xylo-Pfan (TN), Epitope ID:114701, SCHEMBL39891, MLS001361339, CHEMBL502135, cid_135191, BDBM16234, CHEBI:18222, CHEBI:65327, SRBFZHDQGSBBOR-IOVATXLUSA-N, D-(+)-Xylose, analytical standard, Tox21_302055, MFCD00064360, AKOS025401342, D-(+)-Xylose, BioXtra, >=99%, D-(+)-Xylose, puriss., 98.5%, CAS-58-86-6, D-(+)-Xylose, 99%, natural sourced, NCGC00165998-01, NCGC00255319-01, AC-11300, AS-11757, SMR000857378, CS-0083551, C00181, D06346, EN300-118961, G72648, SBI-0633477.0002, D-(+)-Xylose, SAJ special grade, 98.0-101.0%, F8887-9207, WURCS=2.0/1,1,0/(a212h-1x_1-5)/1/, Xylose, European Pharmacopoeia (EP) Reference Standard, Z1255356270, Xylose, United States Pharmacopeia (USP) Reference Standard, D-(+)-Xylose, BioUltra, >=99.0% (sum of enantiomers, HPLC), D-Xylose; Xylose, d-; (+)-Xylose; Xylo-Pfan; D-(+)-Xylose; Wood sugar, DL-Xylose, 58-86-6, (2R,3S,4R)-2,3,4,5-tetrahydroxypentanal, 25990-60-7, aldehydo-D-xylose, (D)-XYLOSE, (+)-Xylose, D-xylo-pentose, Xylose (VAN), 41247-05-6, Xylose, D-, A1TA934AKO, CHEBI:15936, MFCD00151475, (+-)-Xylose, D-(+)-Xylose;(+)-Xylose;Wood sugar, Xylose (Standard), MFCD00198055, ()-Xylos, D-Xylose,(S), XYLOSE [VANDF], XYLOSE [HSDB], XYLOSE [WHO-DD], XYLOSE [MI], DL-Xylose, >=99%, SCHEMBL15776, XYLOSE [ORANGE BOOK], GTPL4724, CHEMBL1236821, HY-N0537R, DTXSID101333192, Pharmakon1600-01300048, HY-N0537, NSC760130, s2124, AKOS015893065, CCG-231055, CS-4824, D-Xylose 1000 microg/mL in Methanol, DB09419, DS-7921, NSC-760130, DB-220423, DB-230291, (2R,3S,4R)-2,3,4,5-tetrahydroxypentana, NS00071570, SW220286-1, X0019, X0020, C74347, EN300-107152, X-7910, X-7950, AB00375890_02, SR-05000002382, D-xylose (open structure, complete stereochemistry), J-520430, SR-05000002382-1, W-202083, BRD-K10759144-001-03-5, BRD-K10759144-001-04-3, Q27077130, Z1255438834, 25702-75-4, D-Xylose, Xylose, d-, (+)-Xylose, Xylo-Pfan, D-(+)-Xylose, Wood sugar, D‑Xylose, (+)-Xylose, aldehydo‑D‑xylose, wood sugar, D‑Xyl, D‑Xylopyranose, D‑Xylulose (occasionally misused), Pentose, Xylose, Xylo‑Pfan

D-Xylose (cf.Ancient Greek: ξύλον, xylon, "wood") is a sugar first isolated from wood, and named for it.
D-Xylose is classified as a monosaccharide of the aldopentose type, which means that it contains five carbon atoms and includes an aldehyde functional group.

D-Xylose is derived from hemicellulose, one of the main constituents of biomass.
Like most sugars, D-Xylose can adopt several structures depending on conditions.
With its free aldehyde group, D-Xylose is a reducing sugar.

D-xylopyranose is d-Xylose in its pyranose form.
D-Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group.
D-Xylose is a sugar isolated from wood.

D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage.
D-Xylose has also been used as a diagnostic agent to observe malabsorption.
Reduction of D-Xylose by catalytic hydrogenation produces the common food additive sweetener substitute xylitol.

The dextrorotary form of xylose, D-xylose, refers usually to the endogenously occurring form of the sugar in living things.
The levorotary form, L-xylose, can refer to the form that is synthesized.
Nevertheless, xylose by itself may not necessarily serve many purposes immediately - but its metabolism results in a variety of substrates that can serve important nutritional and biological purposes.

D-Xylose is a metabolite found in or produced by Escherichia coli.
D-Xylose has been reported in Malus, Elliottia paniculata, and other organisms with data available.
D-Xylose  is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group.

D-Xylose is a sugar isolated from wood.
D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage.
D-Xylose is soluble in water.

D-Xylose is classified as a monosaccharide of the aldopentose type.
D-Xylose , With its free aldehyde group, it is a reducing sugar.
D-Xylose is a five-carbon sugar and includes an aldehyde functional group that contributes to lignocellulose in plants.

D-Xylose is predominantly found in hardwoods and agricultural residues.
D-xylose absorption is a laboratory test to check how well the intestines absorb a simple sugar (D-xylose).
The test helps detect if nutrients are being properly absorbed.

D-Xylose is a form of sugar that comes from woody substances such as straw, corn cobs, pecan shells, and cottonseed hulls.
There are a number of benefits to using D-Xylose instead of regular table sugar.
D-Xylose is safe, healthy, toxin-free, and allows people to indulge their appetites for sweet food without weight gain and other issues commonly associated with sugar.

The sweetener may help fight infections, restore hormonal imbalances, and treat other health problems.
D-Xylose substitute became popular in Japan and throughout Europe in the 1960s.
D-Xylose was successfully introduced in the United States upon approval by the FDA in 1963.

Since that time, D-Xylose has served as both a food sweetener and as a remedy for certain health problems.
As a sweetener, D-Xylose provides a much healthier alternative to regular sugar.

The rate at which the body absorbs table sugar is much higher than the rate of D-Xylose absorption.
People can consume far more of D-Xylose without any ill effects.

USES and APPLICATIONS of D-XYLOSE:
Applications of D-Xylose: Chemicals: The acid-catalysed degradation of hemicellulose gives furfural, a precursor to synthetic polymers and to tetrahydrofuran.
D-Xylose is used to prepare furfural by acid catalyzed degradation reaction, which acts as a solvent as well as a precursor to synthetic polymers.

D-Xylose is a useful animal medicine involved in the treatment of malabsorption.
D-Xylose finds application in the production of sugar substitute xylitol by subjecting xylose to calyticl hydrogenation process.
D-Xylose is found that it undergoes an atmospheric-pressure enzyme (polyphosphate xylulokinase) driven process to get hydrogen.

D-Xylose has also been used as a diagnostic agent to observe malabsorption.
Reduction of xylose by catalytic hydrogenation produces the common food additive sweetener substitute xylitol Xylitol.
The dextrorotary form of xylose, D-xylose, refers usually to the endogenously occurring form of the sugar in living things.

The levorotary form, L-xylose, can refer to the form that is synthesized.
Nevertheless, xylose by itself may not necessarily serve many purposes immediately - but its metabolism results in a variety of substrates that can serve important nutritional and biological purposes.

D-Xylose is used to prepare furfural by acid catalyzed degradation reaction, which acts as a solvent as well as a precursor to synthetic polymers.
D-Xylose is a useful animal medicine involved in the treatment of malabsorption.

D-Xylose finds application in the production of sugar substitute xylitol by subjecting xylose to calyticl hydrogenation process.
D-Xylose is found that it undergoes an atmospheric-pressure enzyme (polyphosphate xylulokinase) driven process to get hydrogen.
Diagnostic: D-Xylose is used in the D‑xylose absorption test to assess small‑intestinal mucosal absorption; reduced urinary excretion indicates malabsorption (e.g. celiac disease, bacterial overgrowth)

Industrial: D-Xylose is used raw material for furfural production via acid‑catalyzed degradation of hemicellulose; furfural is a precursor for polymers and solvents
Food: D-Xylose is used as a low‑calorie sweetener, especially for diabetics; contains ~2.4 kcal/g (about half of glucose)

Biotechnology: D-Xylose is used to stimulate microbial growth, biofilm formation, screening substrates, or in microbial fermentation to produce xylitol or ethanol
Pharmaceutical & medical research: D-Xylose is used as intermediate, in absorption studies, in veterinary/animal diagnostics

-Human consumption of D-Xylose:
D-Xylose is metabolised by humans, although it is not a major human nutrient and is largely excreted by the kidneys.
Humans can obtain D-Xylose only from their diet.
An oxidoreductase pathway is present in eukaryotic microorganisms.

Humans have enzymes called protein xylosyltransferases (XYLT1, XYLT2) which transfer D-Xylose from UDP to a serine in the core protein of proteoglycans.
D-Xylose contains 2.4 calories per gram (lower than glucose or sucrose, approx. 4 calories per gram).

-Animal medicine uses of D-Xylose:
In animal medicine, D-Xylose is used to test for malabsorption by administration in water to the patient after fasting.
If D-Xylose is detected in blood and/or urine within the next few hours, it has been absorbed by the intestines.

High D-Xylose intake on the order of approximately 100 g/kg of animal body weight is relatively well tolerated in pigs, and in a similar manner to results from human studies, a portion of the D-Xylose ingested is excreted in urine unmodified.

ADDITIONAL NOTES & BENEFITS of D-XYLOSE:
*Low‑calorie sweetener: 
~2.4 kcal/g vs ~4 kcal/g for glucose or sucrose; useful in diabetic or low‑sugar applications

*Diagnostic value: 
non‑enzymatic absorption allows evaluation of mucosal health independently of pancreatic function

*Biotechnological potential: 
microbial conversion to xylitol or biofuels; engineering yeast or bacteria to ferment xylose for renewable chemicals

*Environmentally relevant: 
derived from plant biomass (hemicellulose), making it a sustainable feedstock for industrial biochemical processes