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Diethyl phthalate (DEP) is a phthalate ester.
Diethyl Phthalate (DEP) is a colourless liquid without significant odour but with a bitter disagreeable taste.
Diethyl Phthalate (DEP) finds some use as a specialist plasticiser in PVC, it has also been used as a blender and fixative in perfume.
CAS Number: 84-66-2
Chemical formula: C12H14O4
Molar mass: 222.24 g/mol
Synonyms
1,2-Benzenedicarboxylic Acid 1,2-Diethyl Ester; 1,2-Benzenedicarboxylic Acid Diethyl Ester; Phthalic Acid Diethyl Ester; Anozol; DEP; Diethyl 1,2-Benzenedicarboxylate; Diethyl Phthalate;Ethyl Phthalate; NSC 8905; Neantine; Palatinol A; Phthalol; Placidol E; Solvanol; Unimoll DA; o-Benzenedicarboxylic Acid Diethyl Ester;
Diethyl Phthalate (DEP) acts as a fixative and plasticizer.
Diethyl Phthalate (DEP) is diethyl ester of phthalic acid and is slightly denser than liquid water.
Recommended for the manufacturing of attars, fragrances and perfumes.
Diethyl Phthalate (DEP) can be used as a camphor substitute.
Diethyl Phthalate (DEP) is KOSHER, HALAL, REACH, ISO 9001 and HACCP certified.
The shelf life of Diethyl Phthalate (DEP) is 24 months.
Diethyl phthalate is an organic compound that is used in wastewater treatment.
Diethyl Phthalate (DEP) has been shown to have a matrix effect on analytical methods, such as gas chromatography and liquid chromatography.
Diethyl Phthalate (DEP) is not commonly found in the environment because it does not hydrolyze readily in water.
However, Diethyl Phthalate (DEP) can be detected in maternal blood and breast milk due to its ability to cross the placenta and mammary gland barrier.
Diethyl Phthalate (DEP) has a reactive nature and may be carcinogenic.
Diethyl Phthalate (DEP) has been shown to cause DNA damage in vitro assays with human cells, but not with rat cells or bacteria.
Diethyl Phthalate (DEP) may also cause cell lysis when exposed to water, which may lead to death of aquatic organisms.
Diethyl Phthalate (DEP) is a colorless liquid that has a bitter, disagreeable taste.
This synthetic substance is commonly used to make plastics more flexible.
Products in which Diethyl Phthalate (DEP) is found include toothbrushes, automobile parts, tools, toys, and food packaging.
Diethyl Phthalate (DEP) can be released fairly easily from these products, as Diethyl Phthalate (DEP) is not part of the chain of chemicals (polymers) that makes up the plastic.
Diethyl Phthalate (DEP) is also used in cosmetics, insecticides, and aspirin.
Diethyl Phthalate (DEP) appears as a clear, colorless liquid without significant odor. More dense than water and insoluble in water.
Hence sinks in water.
Primary hazard is to the environment. Spread to the environment should be immediately stopped. Easily penetrates soil, contaminates groundwater and nearby waterways.
Flash point 325 °F.
Severely irritates eyes and mildly irritates skin.
Used in the manufacture of perfumes, plastics, mosquito repellents and many other products.
Diethyl Phthalate (DEP) is the diethyl ester of benzene-1,2-dicarboxylic acid.
Diethyl Phthalate (DEP) has a role as a teratogenic agent, a neurotoxin and a plasticiser.
Diethyl Phthalate (DEP) is a phthalate ester, a diester and an ethyl ester.
Diethyl Phthalate (DEP) is a member of the group of esters of phthalic acid known as phthalates, used ubiquitously as solvents and plasticisers worldwide.
Diethyl Phthalate (DEP) can increases the flexibility of plastics.
Diethyl Phthalate (DEP) is also contained in deodorant formulations, perfumes, emollients and insect repellents.
Diethyl Phthalate (DEP) can cross react with dimethyl phtalate.
A clear, colorless liquid without significant odor.
More dense than water and insoluble in water.
Hence sinks in water. Primary hazard is to the environment.
Spread to the environment should be immediately stopped.
Easily penetrates soil, contaminates groundwater and nearby waterways.
Flash point 325°F.
Severely irritates eyes and mildly irritates skin.
Used in the manufacture of perfumes, plastics, mosquito repellents and many other products.
Chemical Properties
Diethyl Phthalate (DEP) is a clear, colorless, oily liquid.
Diethyl Phthalate (DEP) is practically odorless, or with a very slight aromatic odor and a bitter, disagreeable taste.
Diethyl Phthalate (DEP) is miscible with ethanol and ethyl ether.
Diethyl Phthalate (DEP) is soluble in acetone, benzene, carbon tetrachloride, alcohols, ketones, esters, and aromatic hydrocarbons and partly miscible with aliphatic solvents.
Diethyl Phthalate (DEP), when exposed to heat, decomposes and emits acrid smoke and irritating fumes.
Diethyl Phthalate (DEP) is incompatible with strong oxidisers, strong acids, nitric acid, permanganates, and water and attacks some forms of plastics.
Diethyl Phthalate (DEP) is produced in the reaction of phthalic anhydride with ethanol in the presence of concentrated sulphuric acid catalyst.
Physical properties
Clear, colorless, oily liquid with a mild, chemical odor.
Bitter taste.
Virtually odorless when pure ("Perfumery grade" of commercial Diethyl phthalate).
Very bitter taste in weak hydro-alcoholic solution.
Bitter taste perceptible below 20 ppm.
Uses
Diethyl Phthalate (DEP) is a Plasticizer for cellulose ester plastic films and sheets; in molded plastics; manufacturing varnishes; cosmetics.
Diethyl Phthalate (DEP) is an intermediate of the rodenticides dimouse, murine, and chlorpyrone, and is also an important solvent.
Diethyl Phthalate (DEP) is used as a plasticizer for plastics.
Diethyl Phthalate (DEP) is used as an analytical reagent, a gas chromatography stationary solution, a solvent for cellulose and esters, a plasticizer and a lubricant.
Diethyl Phthalate (DEP) is used as plasticizer, solvent, lubricant, fixative, foaming agent for colored or rare metal mine flotation, gas chromatography fixative, alcohol denaturant, spray insecticide.
Diethyl Phthalate (DEP)t is mixed with cellulose acetate, cellulose acetate butyrate, polyvinyl acetate, nitrocellulose, ethyl cellulose, polymethyl methacrylate, polystyrene, polyvinyl butyral, vinyl chloride-vinyl acetate Most resins such as copolymers have good compatibility.
Diethyl Phthalate (DEP) is mainly used as a plasticizer for cellulose resin, but the product has high volatility, which limits its wide application.
Diethyl Phthalate (DEP) has been used as a substitute for camphor in the manufacture of celluloid, as a solvent for cellulose acetate in the manufacture of varnishes and dopes, as a ftxative for perfumes, and for denaturing ethanol.
Pharmaceutical Applications
Diethyl Phthalate (DEP) is used as a plasticizer for film coatings on tablets, beads, and granules at concentrations of 10–30% by weight of polymer.
Diethyl Phthalate (DEP) is also used as an alcohol denaturant and as a solvent for cellulose acetate in the manufacture of varnishes and dopes.
In perfumery, Diethyl Phthalate (DEP) is used as a perfume fixative at a concentration of 0.1–0.5% of the weight of the perfume used.
Production Methods
Diethyl Phthalate (DEP) is produced by the reaction of phthalic anhydride with ethanol in the presence of sulfuric acid.
Reactivity Profile
Diethyl Phthalate (DEP) is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Can generate electrostatic charges.
