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Diethylamine is an organic compound with the formula (CH3CH2)2NH. Diethylamine is a secondary amine. Diethylamine is a flammable, weakly alkaline liquid that is miscible with most solvents. Diethylamine is a colorless liquid, but commercial samples often appear brown due to impurities. Diethylamine has a strong ammonia-like odor.
CAS NUMBER: 109-89-7
SYNONYM:
Diethylamine; N-Ethylethanamine; 109-89-7; N,N-Diethylamine; Ethanamine, N-ethyl-; Diethamine; Diaethylamin; Dwuetyloamina; Dietilamina; diethyl amine; Diethylamin; Diethyl-amine; Diaethylamin; Dietilamina; Dwuetyloamina; UNII-B035PIS86W; CCRIS 4792; HSDB 524; Et2NH; (C2H5)2NH; EINECS 203-716-3; MFCD00009032; UN1154; AI3-24215; B035PIS86W; CHEBI:85259; N-Ethyl-Ethanamine; Diethylamine, 99+%, extra püre; Diethylamine, 99.5%, for analysis; Diethylamine, 99.5%, extra pure, redistilled; dietylamine; di-ethylamine; N,N-diethyl amine; diethylamine (DEA); Diethylamine, 98%; Diethylamine Anhydrous; Diethylamine, BioXtra; HNEt2; PubChem17237; C[C]NCC; ACMC-1BS8V; DSSTox_CID_1909; EC 203-716-3; Diethylamine, >=99.5%; CHEMBL1189
Diethylamine is a colourless, strongly alkaline, fish odour liquid, and highly inflammable. Diethylamine has an ammonia-like odour and is completely soluble in water. On burning, diethylamine releases ammonia, carbon monoxide, carbon dioxide, and nitrogen oxides. Diethylamine is incompatible with several chemical substances such as strong oxidisers, acids, cellulose nitrate, some metals, and dicyanofuroxan. N-nitrosamines, many of which are known to be potent carcinogens, may be formed when diethylamine comes in contact with nitrous acid, nitrates, or atmospheres with high nitrous oxide concentrations. The applications of Diethylamine are numerous. Diethylamine is used in the production of pesticides. Diethylamine is used in a mixture for the production of DEET which goes into the repellents that are found readily in supermarkets for general use. Diethylamine is also mixed with other chemicals to form Diethylaminoethanole, which is used mainly as a corrosion inhibitor in water treatment facilities as well as production of dyes, rubber, resins, and pharmaceuticals. Diethylamine is also used in manufacture of basic chemicals and pharmaceuticals.
Diethylamine is made by the alumina-catalyzed reaction of ethanol and ammonia. Diethylamine is obtained together with ethylamine and triethylamine. Annual production of three ethylamines was estimated in 2000 to be 80,000,000 kg. Diethylamine is used in the production of corrosion inhibitor N,N-diethylaminoethanol, by reaction with ethylene oxide. Diethylamine is also a precursor to a wide variety of other commercial products. Diethylamine is also sometimes used in the illicit production of LSD. Diethylamine is the smallest and simplest molecule that features a supramolecular helix as its lowest energy aggregate. Other similarly sized hydrogen-bonding molecules favor cyclic structures. Diethylamine has low toxicity, but the vapor causes transient impairment of vision.
Diethylamine appears as a clear colorless liquid with an ammonia-like odor. Density 5.9 lb / gal. Flash point -15°F. A respiratory irritant. Corrosive to the eyes and skin. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. Diethylamine is a secondary aliphatic amine where both N-substituents are ethyl. Diethylamine is a conjugate base of a diethylammonium. Diethylamine has been used to constitute the extraction solvent mixture for the gas chromatography-mass spectrometric (GC-MS) analysis of melamine and related compounds. Diethylamine has been also been used as a bond breaking agent in a novel ELISA technique to measure the avidity index (AI) of IgG-anti-PT (Immunoglobulin G-anti-pertussis toxin) antibodies. Diethylamine is a corrosive skin and eye irritant and severe respiratory tract irritant.
Diethylamine is a primary skin irritant and is an irritant to the eyes and mucous membranes. The dermal LD50 in rabbits was 580 mg kg−1. An inhalation LC50 of 4000 ppm in rats was reported for a 4 h exposure. The oral LD50 in rats has been reported to be 540 mg kg−1. Intraperitoneal injection in rats resulted in a moderate inhibitory effect with respect to liver function and monoamine oxidase activity. Diethylamine is a severe skin and eye irritant. Eye exposure to diethylamine can cause edema of the corneal epithelium, generally without pain and causing colored halos around lights. This effect generally clears within 24 h. Intense eye exposures cause blurring, photophobia, and discomfort from the roughness of the corneal epithelium. Direct contact with skin has a corrosive effect, causing erythema and blistering. Respiratory tract irritation is expected from inhalation exposures. Ingestion of diethylamine causes severe burns to the oral tissues, with emesis, abdominal pain, and diarrhea. Diethylamine is a severe skin and eye irritant. Eye exposure to diethylamine can cause burning discomfort, spasmodic blinking or involuntary closing of the eyelids, redness, tearing, blue/gray hazy vision, halos, and edema of the corneal epithelium, generally without pain and clearing within a day. Five to 25 ppm exposures result in slight visual disturbances.
More intense eye exposures cause blurring, photophobia, and discomfort from the roughness of the corneal epithelium which clears in several days. Conjunctival hemorrhages, corneal opacities, and keratitis may occur with exposure to higher concentrations and may result in permanent damage and impairment of vision. Diethylamine is a secondary amine which belongs to the class of dialkylamines and is produced from Bio-Ethanol, a renewable resource. Diethylamine is a verstile intermediate for synthesis reactions. Diethylamine is used for the production of DEET, a very well known insect repellent. As a neutralizating agent, Diethylamine is used to neutralise and solubilise a variety of resins for water-soluble paints. Diethylamine is a versatile intermediate for synthesis reactions. Diethylamine is utilised in the production of rubber chemicals, for example, tetraethyl thiuram disulphide. Diethylamine is used for the production of Diethylaminoethanol, a product used mainly in water treatment as corrosion inhibitor. Diethylamine is a secondary amine with the molecular structure CH3CH2NHCH2CH3. Diethylamine is a flammable, strongly alkaline liquid. Diethylamine is miscible with water and ethanol. Diethylamine is a colorless liquid which often appears brown due to impurities. Diethylamine is volatile and has a strong unpleasant odor.
IUPAC NAME:
DEA; Diethylamine; diethylamine; Diethylamine; N,N-DIETHYLAMINE; N-ethylethanamine, N-ethylethanamine; n-etiletanamina
TRADE NAME:
DEA; Diethylamin; Diethylamine; Diethylamine (8CI); ethanamine, N-ethyl-; Ethanamine, N-ethyl- (9CI); N,N-Diethylamine
OTHER NAME:
109-89-7; 1637232-73-5; 612-003-00-X
Colorless liquid with a fishy, ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 60 μg/m3 (20 ppbv) and 180 μg/m3 (60 ppbv), respectively. Diethylamine is a very strong base in aqueous solution (pKb = 3.0). Diethylamine is chemistry is governed by the unshared electron pair on the nitrogen, thus Diethylamine tends to react with acids to form salts. Diethylamine occurs in low concentrations in food and other biological materials. Concentrations (in p.p.m.) in fresh products include: spinach, apples, butterbeans, shelled peas, bean salad and red cabbage. Pickled vegetables contain p.p.m. diethylamine while concentrations in other materials include herring, barley, hops, boiled beef, tobacco leaf and cigarette smoke concentrate. Interest in the occurrence of diethylamine in foods arises in part because of its possible formation of a carcinogenic N-nitroso derivative. Diethylamine has been reported in the exhaust from a gasoline engine. In flotation agents, resins, dyes, resins, pesticides, rubber chemicals, and pharmaceuticals; selective solvent; polymerization and corrosion inhibitors; petroleum chemicals; electroplating; organic synthesis.
Diethylamine is manufactured by heating ethyl chloride and alcoholic ammonia under pressure or by hydrogenation of aziridines in the presence of catalysts. Diethylamine is used as a solvent, as a rubber accelerator, in the organic synthesis of resins, dyes, pesticides, and pharmaceuticals, in electroplating, and as a polymerization inhibitor. Other applications include uses as a corrosion inhibitor. Diethylamine was reported noneffective as a skin depigmentator. Diethylamine is produced using the three methods also used for the manufacture of ethylamine with very slight modification. The most widely used method is the passing of ammonia and ethanol over a catalyst such as alumina or silica. Diethylamine can be separated from the mixture by selective distillations and extractions. This secondary amine can also be produced by the other two methods which involve: 1) passing ammonia, ethanol, and hydrogen over a dehydrogenation catalyst; and 2) passing ammonia and an aldehyde or ketone and hydrogen over a hydrogenation catalyst. U.S. production in 1984 is estimated at 19.7 million pounds.
A clear colorless liquid with an ammonia-like odor. Density 5.9 lb / gal. Flash point -15°F. A respiratory irritant. Corrosive to the eyes and skin. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. Highly flammable. Soluble in water. Sensitive to heat. May be sensitive to prolonged exposure to air. Diethylamine is a colourless, strongly alkaline, fish odour liquid, and highly inflammable. Diethylamine has an ammonia-like odour and is completely soluble in water.Causes ignition on contact with cellulose nitrate. Explodes on contact with dicyanofurazan or dicyanofuroxan. Attacks some forms of plastics, rubber and coatings. On burning, diethylamine releases ammonia, carbon monoxide, carbon dioxide, and nitrogen oxides. Diethylamine is incompatible with several chemical substances such as strong oxidisers, acids, cellulose nitrate, some metals, and dicyanofuroxan. N-nitrosamines, many of which are known to be potent carcinogens, may be formed when diethylamine comes in contact with nitrous acid, nitrates, or atmospheres with high nitrous oxide concentrations.
Diethylamine can be harmful if Diethylamine is inhaled, swallowed, or in contact with skin. Vapors can irritate the eyes and cause irritation of the respiratory tract, leading to coughing and chest pain. Liquid diethylamine can cause severe burns to the eyes and skin. Vision became misty and halos appeared several hours after workmen were exposed to the vapors of amines such as diethylamine. The edema of the corneal epithelium, which is principally responsible for the disturbances in vision, clears after one or more days, depending on the severity of exposure. Photophobia and discomfort from roughness of the corneal surface also can occur after greater exposure to the amine. Diethylamine, like many of the other short chain aliphatic amines, has achieved widespread industrial use as an intermediate in the manufacture of a number of commercial products. Among these are included insecticides, pharmaceuticals, textile finishing agents, and corrosion inhibitors. Diethylamine is used as a polymerization inhibitor and/or catalyst in the polymer industry and in the manufacture of surfactants and rubber processing accelerators.
This amine also is useful as a depilatory agent for animal skins, as a selective solvent for the removal of impurities from oils, fats, and waxes, and as a flotation agent in the petroleum industry. Moderately toxic by ingestion, inhalation, and skin contact. A skin and severe eye irritant. Exposure to strong vapor can cause severe cough and chest pains. Contact with liquid can damage eyes, possibly permanently; contact with skin causes necrosis and vesciculation. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Explodes on contact with dicyanofurazan. Violent reaction with sulfuric acid. Ignites on contact with cellulose nitrate of sufficiently high surface area. When heated to decomposition Diethylamine emits toxic fumes of NOx. No evidence of mutagenicity was seen in Ames bacterial assays.8 Diethylamine has an ammonia-like odor that is detectable at 0.13ppm. The 2003 ACGIH threshold limit valuetime- weighted average (TLV-TWA) for diethylamine is 5ppm (15mg/m3) with a short-term excursion limit of 15ppm (45mg/m3) and an A4-not classifiable as a human carcinogen designation; there is a notation for skin absorption.
Diethylamine reacted with NOx in the dark forming diethylnitrosamine. In an outdoor chamber, photooxidation by natural sunlight yielded the following products: diethylnitramine, diethylformamide, diethylacetamide, ethylacetamide, ozone, acetaldehyde, and peroxyacetyl nitrate. Little information is available regarding the metabolism of diethylamine. The amine can be readily absorbed from the respiratory and gastrointestinal tract. Diethylamine has been reported that following oral administration of diethylamine hydrochloride to humans, much of the amine was recovered in the urine (Beard and Noe 1978). This suggests that Diethylamine is not readily metabolized and, therefore, may not be a substrate for monoamine oxidase. When administered intraperitoneally to rats, Diethylamine was moderately inhibitory with respect to liver monoamine oxidase (Valiev 1974). Diethylamine may serve as a precursor for the formation of the reportedly carcinogenic N-nitrosoamines and, indeed, when a diethylamine containing liquid was examined for nitrosation reactions under simulated conditions of the human stomach, N-nitrosodiethylamine was formed.
Diethylamine should be protected from physical damage. Diethylamine should be kept stored in a cool, dry, well-ventilated location, away from incompatible chemical substances and away from fi re hazard and smoking areas. The containers should be bonded and grounded for transfer to avoid static sparks. Storage and use areas should be no smoking areas. Dry diethylamine with LiAlH4 or KOH pellets. Reflux with, and distil Diethylamine from, BaO or KOH. Convert Diethylamine to the p-toluenesulfonamide and crystallise to constant melting point from dry pet ether (b 90-120o), then hydrolyse with HCl, excess NaOH is added, and the amine is passed through a column of activated alumina. Redistil the amine and dry Diethylamine with activated alumina before use polystyrene diethylaminomethyl supported version is commercially available. Occupational workers and users should be very careful during the use and chemical management of diethylamine. Workers should wear impervious protective clothing, including boots, gloves, a laboratory coat, apron or coveralls, as appropriate, to prevent skin contact. The chemical is very hazardous, corrosive, and harmful, and is a very flammable liquid and vapor. Exposures to vapor may cause flash fire.
Diethylamine causes burns and adverse effects to the cardiovascular system. Workers should use chemical safety goggles and a full-face shield to avoid splashing of the chemical substance. An eye-wash fountain and quickdrench facilities in the work area should be maintained by the chemical management unit. Diethylamine is an organic compound with the formula (CH3CH2) 2NH. Diethylamine is a secondary amine. Diethylamine is a flammable, weakly alkaline liquid that can be mixed with most solvents. Diethylamine is a colorless liquid, but commercial samples often appear brown due to impurities. Diethylamine has a strong odor similar to ammonia. Diethylamine is a secondary amine belonging to the dialkylamine class and produced from Bio-Ethanol, a renewable source. Diethylamine is a secondary amine whose molecular structure is CH3CH2NHCH2CH3. Diethylamine is a flammable, strongly alkaline liquid. Miscible with water and ethanol. Diethylamine is a colorless liquid that often appears brown due to impurities. Diethylamine is volatile and has a strong unpleasant odor.
Diethylamine is made by the reaction of diethylamine, ethanol and ammonia catalyzed by alumina. Diethylamine is obtained together with ethylamine and triethylamine. In 2000, the annual production of three ethylamines was estimated to be 80,000,000 kg. Diethylamine is used in the production of corrosion inhibitor N, N-diethylaminoethanol by reacting with ethylene oxide. Diethylamine is also a precursor to a wide variety of other commercial products. Diethylamine is also sometimes used in the illegal production of LSD. Diethylamine is the smallest and simplest molecule that has a supramolecular helix as its lowest energy aggregate. Other hydrogen-bonding molecules of similar size support cyclic structures. Diethylamine has low toxicity, but vapor causes temporary visual impairment. Diethylamine is a secondary amine with molecular structure CH3CH2NHCH2CH3 and belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups attached to the amino nitrogen
. Diethylamine is a colorless liquid that is miscible with water and ethanol. Diethylamine is a powerful basic compound. Diethylamine has a volatile, unpleasant odor and an ammonia and fishy flavor. Diethylamine is found in the highest concentrations in barley and apples and has also been found in common grape, corn, and spinach leaves. This could make diethylamine a potential biomarker for consumption of these foods. Diethylamine appears as a clear colorless liquid with an ammonia-like odor. Density 5.9 lb / gal. Flash point -15 ° F. Irritating to respiratory tract. Diethylamine corrodes eyes and skin. Vapors heavier than air. Toxic nitrogen oxides formed during combustion. Diethylamine is a secondary aliphatic amine in which both N-substituents are ethyl. Diethylamine is a conjugate base of a diethylammonium. Diethylamine, also known as DEA or (C2H5) 2nh, belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups attached to the amino nitrogen. Diethylamine is a colorless liquid that often appears brown due to impurities.
Diethylamine is a very strong basic compound (with respect to pKa). Diethylamine is volatile and has a strong unpleasant odor. Diethylamine is an ammoniacal and fish-flavored compound. Outside of the human body, Diethylamine is found on average in barley and apples at the highest concentration. Diethylamine has also been detected, but has not been measured in a few different foods such as common grapes, corn, and spinach. This could make diethylamine a potential biomarker for consumption of these foods. Diethylamine is a potentially toxic compound. Miscible with water and ethanol. Diethylamine is a secondary amine whose molecular structure is CH3CH2NHCH2CH3. Diethylamine is a flammable, strongly alkaline liquid. Diethylamine is a serious skin and eye irritant Diethylamine is a secondary aliphatic amine in which both N substituents are ethyl. Diethylamine is a secondary aliphatic amine. Diethylamine is the conjugate base of diethylammonium. N- (trimethylsilyl) diethylamine has a functional parent diethylamine. Diethylammonium is the conjugate acid of diethylamine. Diethylamine is used as a corrosion inhibitor and in the production of rubber, textiles, resins, electroplating, paints and pharmaceuticals. Diethylamine is also commonly found in many insecticides.
Diethylamine is a verstile intermediate for synthesis reactions. Diethylamine is used in the production of DEET, a well-known insect repellent. As a neutralizing agent, Diethylamine is used to neutralize and dissolve various resins for water-soluble paints. Diethylamine is a versatile intermediate for synthesis reactions. Diethylamine is used in the production of rubber chemicals such as tetraethyl thiuram disulfide. Diethylamine is mainly used in the production of Diethylaminoethanol, a product used as a corrosion inhibitor in water treatment. Diethylamine is a colorless, viscous liquid organic chemical compound that is both a secondary amine and a dialcol. The compound is suspected of being a carcinogen to humans, according to the International Research Agency. Hydrophilic liquid is used as a surfactant and a corrosion inhibitor. Diethylamine is also used to remove natural gas from hydrogen sulfide.
Diethylamine is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat developed per mole of amine in neutralization is largely independent of the strength of the amine as a base. Diethylamine may be incompatible with amines, isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides and acid halides. Combustible gaseous hydrogen is produced by amines in combination with strong reducing agents such as hydrates. This compound is hygroscopic. Exposure to air and light can be sensitive. This compound can react with oxidizing agents, acids, CO2, copper alloys, aluminum, zinc, galvanized iron and copper. Diethylamine is used in the preparation of morpholine and diethanolamides, an active ingredient in cosmetics and shampoos. Diethylamine acts as a surfactant and a corrosion inhibitor. Diethylamine is used for the removal of hydrogen sulphide and carbon dioxide from natural gas. Diethylamine is also an intermediate used in rubber chemicals, as a moisturizing and softening agent, and as an emulsifier and dispersant in agricultural chemicals. In addition, Diethylamine is used to cut oils, cleansers, soaps, polishers and medicines.
Acute inhalation exposure to dietuanolamine in humans may cause irritation to the nose and throat, and skin exposure may cause skin irritation. Animal studies show that exposure to diethanolamine via intravenous injections can cause increased blood pressure, dilatation of the pupil and salivation. Sedation and coma may occur in animals at very high doses. Acute animal studies have shown that dermal exposure to diethanolamine can burn the skin and eye contact with the chemical can impair vision. Acute animal tests in rats have shown diethanolamine to be of moderate acute toxicity from oral exposure. After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.
There is no information about the chronic effects of Diethylamine in humans. Animal studies have reported the effects of liver, kidney, blood, and CNS from chronic oral exposure to dietary ethanolamine. Skin lesions were observed in mice following daily topical administration Diethylamine of. EPA did not establish a Reference Concentration (RfC) or a Reference Dose (RfD) for diethanolamine. The California Environmental Protection Agency (CalEPA) has established a chronic reference exposure level of 0.02 milligrams per cubic meter (mg / m) for diethanolamine based on effects on blood in rats. The reference exposure level for TheCalEPA is one or lower concentration at which adverse health effects are unlikely to occur. This is not a direct risk estimator, but a reference point for measuring potential impacts. At lifetime exposure, the potential for adverse health effects increases with exposure more and more than the reference exposure level.
There is no information about the reproductive or developmental effects of Diethylamine in humans. Animal studies have reported reduced testicular degeneration and sperm motility and exposure to Diethylamine orally. Diethylamine can cause necrosis to the skin. Rabbits exposed to 100 ppm, 7 hours/day, 5 days/week for 6 weeks have bronchopneumonia; If left on clothing, can cause reddening of skin; Corrosive to skin; Causes liver damage in high-dose animal studies; A corrosive substance that can cause pulmonary edema.
Diethylamine can be used as a better template for the crystallization of the silicoaluminophosphate molecular sieves with high purity and crystallinity as compared to other templates. Diethylamine can react with furfural and cyanoacetic ester to form bicyclo octanes. Diethylamine can also be used as an amino functionalized monomer which can interact with chitosan to synthesize hydrogel with potential applications in drug delivery systems.
Diethylamine is a secondary amine that is a flammable, strongly alkaline liquid. Diethylamine is also very soluble, and can be mixed to form a solution with water and ethanol. Diethylamine is a clear liquid which may appear brown because of it's impurities. Diethylamine is volatile and has a strong nasty smell. Diethylamine can also be made from ethanol and ammonia and is obtained together with ethylamine and triethylamine. One of it's main uses is that of a corrosion inhibitor. Diethylamine is also used in the production of dyes, resins, rubber and pharmaceuticals. This chemical is also used in the production of pesticides. Diethylamine is used for the production of DEET, which can be found in many insect repellents that are sold in supermarkets and stores. Diethylamine is also an extremely corrosive chemical. If Diethylamine comes into contact with bare skin it will likely end up as a major burn or skin irritation.
The primary mechanism of diethylamine responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). Diethylamine also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diethylamine has a low to moderate preference to block the COX2-isoenzyme (approximately 10-fold) and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin. Diethylamine is an organic compound with the formula (CH3CH2)2NH. Diethylamine is a secondary amine. Diethylamine is a flammable, weakly alkaline liquid that is miscible with most solvents. Diethylamine is a colorless liquid, but commercial samples often appear brown due to impurities. Diethylamine has a strong ammonia-like odor. Diethylamine is manufactured by the alumina-catalyzed reaction of ethanol and ammonia.
Diethylamine is obtained together with ethylamine and triethylamine. Diethylamine is used in the production of corrosion inhibitor N,N-diethylaminoethanol, by reaction with ethylene oxide. Diethylamine is also a precursor to a wide variety of other commercial products.
Direct contact with skin has a corrosive effect, causing erythema and blistering. If the skin is wet or moist, contact with the gas or vapor can cause burning pain, inflammation, blisters, and ulceration. The estimated fatal dermal dose of diethylamine for a human is 20 g.
Diethylamine is an organic chemical compound which is both a secondary amine and a di-alcohol. It is di-alcohol because it has two hydroxyl groups in its molecule. Like other amines, Diethylamine acts as a weak base. Diethanolamine is widely used in the preparation of salts of long-chain fatty acids that are formulated into soaps and surfactants used in cosmetics, shampoos, and hair conditioners. Its primary role in most skincare formulations is as a pH adjuster where Diethylamine is used increased the pH of the formulation.
Diethylamine is used in a variety of cosmetic and personal care products, including cosmetics, make-up bases and foundations, as well as in fragrances, hair care products, hair dyes, wave sets, shaving products, sunscreens, and skin care and skin cleansing products. A related compound, Diethylamine is often found in skincare formulations and has similar uses to Diethylamine. Diethylamine is indicated for use in the treatment of pain and inflammation from varying sources including inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and akylosing spondylitis, as well as injury-related inflammation due to surgery and physical trauma. Diethylamine is often used in combination with misoprostol as a gastro-protective agent in patients with high risk of developing NSAID-induced ulcers. Diethylamine reduces inflammation and by extension reduces nociceptive pain and combats fever. Diethylamine also increases the risk of developing a gastrointestinal ulcer by inhibiting the production of protective mucus in the stomach.
Diethylamine, also known as DEA, is a secondary amine with the molecular structure CH3CH2NHCH2CH3 and belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen. Diethylamine is a colorless liquid that is miscible with water and ethanol. Diethylamine is a strong basic compound. It is volatile with a strong unpleasant odor and an ammoniacal and fishy taste. Diethylamine is found in highest concentrations in barley and apples and has also been detected in common grapes, corn, and spinach leaves. This could make diethylamine a potential biomarker for the consumption of these foods. Diethylamine are present in many consumer products ranging from cosmetics, personal care products and household cleaning products. Both have been linked to liver tumors. The European Commission prohibits diethanolamine (Diethylamine) in cosmetics, to reduce contamination from carcinogenic nitrosamines.
Diethylamine is used as a corrosion inhibitor. Diethylamine is also used in the production of rubber, resins, dyes and pharmaceuticals. Diethylamine is also used to cook lysergic acid diethylamide (LSD) and is strictly watched by Drug Enforcement Administration (Diethylamine). Miscible with water, alcohol, ether, chloroform and carbon terachloride.
