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CAS NO:7558-79-4
EC NO:231-448-7
Disodium phosphate anhydrous (DSP), or disodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na2HPO4.
Disodium phosphate anhydrous is one of several sodium phosphates. The salt is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates. All are water-soluble white powders; the anhydrous salt being hygroscopic.
The pH of disodium hydrogen phosphate water solution is between 8.0 and 11.0, meaning it is moderately basic:
HPO42− + H2O ⇌ H2PO4− + OH−
Production and reactions
Disodium phosphate anhydrous can be generated by neutralization of phosphoric acid with sodium hydroxide:
H3PO4 + 2 NaOH → HNa2PO4 + 2 H2O
Industrially Disodium phosphate anhydrous is prepared in a two-step process by treating dicalcium phosphate with sodium bisulfate, which precipitates calcium sulfate:
CaHPO4 + NaHSO4 → NaH2PO4 + CaSO4
In the second step, the resulting solution of monosodium phosphate is partially neutralized:
NaH2PO4 + NaOH → HNa2PO4 + H2O
Uses
Disodium phosphate anhydrous is used in conjunction with trisodium phosphate in foods and water softening treatment. In foods, it is used to adjust pH.
Disodium phosphate anhydrous presence prevents coagulation in the preparation of condensed milk. Similarly, it is used as an anti-caking additive in powdered products.
Disodium phosphate anhydrous is used in desserts and puddings, e.g. Cream of Wheat to quicken cook time, and Jell-O Instant Pudding for thickening. In water treatment, it retards calcium scale formation.
Disodium phosphate anhydrousis also found in some detergents and cleaning agents.
Heating solid disodium phosphate gives the useful compound tetrasodium pyrophosphate:
2 HNa2PO4 → Na4P2O7 + H2O
Laxative
Monobasic and dibasic sodium phosphate are used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.
Properties
Chemical formula Na2HPO4
Molar mass 141.96 g/mol (anhydrous)
177.99 g/mol (dihydrate)
268.07 g/mol (heptahydrate)
Appearance White crystalline solid
Odor odorless
Density 1.7 g/cm3
Melting point 250 °C (482 °F; 523 K) decomposes
Solubility in water 7.7 g/100 ml (20 °C)
11.8 g/100 mL (25 °C, heptahydrate)
Solubility insoluble in alcohol
log P -5.8
Acidity (pKa) 2.15, 6.82, 12.35
Magnetic susceptibility (χ) −56.6·10−6 cm3/mol
Refractive index (nD) 1.35644..1.35717 at 20°C
Disodium phosphate anhydrous, dibasic appears as a colorless to white crystalline solid. Soluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit spread to the environment. Used as a fertilizer, in pharmaceuticals, in food processing, and for many other uses.
Disodium phosphate anhydrous is a sodium phosphate.
Industry Uses
Corrosion inhibitors and anti-scaling agents
Fillers
Intermediates
Laboratory chemicals
Oxidizing/reducing agents
Paint additives and coating additives not described by other categories
Plating agents and surface treating agents
Processing aids, not otherwise listed
Consumer Uses
Air care products
Cleaning and furnishing care products
Fabric, textile, and leather products not covered elsewhere
Food packaging
Laboratory Use
Metal products not covered elsewhere
Non-TSCA use
Water treatment products
USES
-For Disodium phosphate (USEPA/OPP Pesticide Code: 076403) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
-The active ingredient is no longer contained in any registered pesticide products ... "cancelled."
-Alone or combined with monosodium phosphate is used to make starch for instant puddings and pie fillings.
-Emulsifier (processed cheese, quick-cook cereals, pharmaceuticals); metal phosphatising/electroplating reagent); pottery glazes/porcelain/enamels; scale inhibitor (boiling water treatment); textile/leather auxiliary.
Disodium phosphate anhydrous is sodium salt of phosphoric acid and occurs as a white powder which is highly water soluble and hygroscopic.
Disodium phosphate anhydrous is obtained when a solution of phosphoric acid is reacted with caustic soda, until the higher PH is obtained.
Disodium phosphate anhydrous is used as a food enhancer to quicken cooking time; it is used along with trisodium phosphate in boilers; in the medical field, it is used as a laxative, Used in Water Treatment.
Disodium phosphate anhydrous is used in foods as a sequestrant, emulsifier, buffering agent, absorbent, pH control agent, protein modifier, source of alkalinity, stabiliser and nutrient supplement Disodium hydrogen phosphate (Na2HPO4) is a sodium salt of phosphoric acid.
Disodium phosphate anhydrous is a white powder that is highly hygroscopic and water soluble.
Disodium phosphate anhydrous is therefore used commercially as an anti-caking additive in powdered products.
Disodium phosphate anhydrous is also known as disodium hydrogen orthophosphate, sodium hydrogen phosphate or sodium phosphate dibasic.
Disodium phosphate anhydrous is commercially available in both the hydrated and anhydrous forms.
Sources/Uses
Used as emulsifier and buffer in foods and pharmaceuticals, metal phosphatising/electroplating reagent, scale inhibitor (boiling water treatment), textile/leather auxiliary, sequestrant, mordant in dyeing, fireproofing agent, reagent and buffer in analytical chemistry, cathartic, and veterinary laxative; Also used for weighting silk and in pottery glazes/porcelain/enamels, tanning, and soldering/brazing (instead of borax); [HSDB] Used in fertilizers, galvanoplastics, and as a dietary supplement; [Hawley]
Applications
Disodium phosphate anhydrous is used in food and water treatment in conjunction with trisodium phosphate.
Disodium phosphate anhydrous is used as an emulsifier and buffer in foods and pharmaceuticals, anti-caking additive in powdered products, dietary supplement, scale inhibitor, reagent and buffer in analytical chemistry.
Disodium phosphate anhydrous finds application in detergents, cleaning agents, textile, leather auxiliary, fertilizers and galvanoplastics. Further, it is used as a saline laxative to treat constipation.
Disodium phosphate anhydrous inhibits the calcium scale formation in water treatment plants.
Disodium Phosphate is listed within the feed material catalogue ( Regulation (EC) 68/2013. The product complies with the general principles of regulation (EC) 178/2002 and the requirements for feed hygiene according to regulation (EC) 183/2005.
Applications
Feed
Food
Disodium Phosphate Anhydrous Use: Application for food such as emulsifiers, thickening agents, leavening agents.
Appearance: White Oudorless Powder
Assay: 98.0% Min
Specifications - Water Insoluble, %: ≤ 0.2; Arsenic as As, ppm: ≤ 3; Heavy Metal, as Pb: ≤ 10; Lead as Pb, ppm: ≤ 4; Fluoride as F, ppm: ≤ 50; Loss on drying, %: ≤ 5.0.
Disodium Phosphate Anhydrous in Food
Disodium Phosphate Anhydrous’s very common in processed and packaged foods. Some of the purposes it serves in the manufacturing process are:
Emulsifier. This is a chemical that helps to bind fats and water together. Fats don’t mix with many other liquids without help. (Think about oil and vinegar.) Emulsifiers have a chemical structure that helps them mix.
Disodium phosphate is a helpful emulsifier for dairy products and other foods. Cheese, whipped cream, milk, and other dairy products have unique textures and consistencies because of disodium phosphate.
Preservative. Both sodium and phosphorus can help extend foods’ shelf life. Some of the first instances of preserving and curing food used salt.
Disodium phosphate is also helpful in canning food since it prevents metal from rusting.
Flavor enhancer. Processed foods often have additives that strengthen their flavor and make them more savory. Many foods have sodium-containing additives to enhance their flavor.
pH control. A food’s pH level (or level of acidity) can affect its nutritional value, color, and other characteristics. Canning or using jars can alter foods’ pH levels. Disodium phosphate can help control a food’s pH level throughout the production process.
Some common foods that have disodium phosphate are:
Whipped cream
Cheese
Ice cream
Milk
Yogurt
Seafood
Meat
Pasta
Soda
Gelatin powder
Formula: Na₂HPO₄
MW: 141.96 g/mol
Melting Pt: 250 °C
Density: 1.53 g/cm³ (20 °C)
Storage Temperature: Ambient
Disodium Phosphate Anhydrous Granular & Powder is a white, odorless, free flowing powder.
Disodium Phosphate AnhydrousThis product is known for its alkalinity and is used as a buffering agent, protein modifier, stabilizer, and emulsifying agent.
Disodium Phosphate Anhydrous is commonly used during production of spray dried cheese and nonfat milk powders.
Disodium Phosphate Anhydrous protects the milk proteins from heat dehydration allowing the proteins to remain dispersed during the spray drying process, which assists in the solubility of the powders upon reconstitution with water.
Disodium Phosphate Anhydrous also stabilizes the emulsion to enhance flavor, body, and appearance of the final product.
Disodium Phosphate Anhydrous is a sodium salt of phosphoric acid.
Disodium Phosphate Anhydrous is a white powder that is highly hygroscopic and water soluble.
Disodium Phosphate Anhydrous has been used for preparing phosphate buffer which in turn is utilized in X-gal staining.
Used as a pH buffer, stabilizer and emulsifier in processed cheese, condensed milk, instant pudding and other food applications.
Disodium Phosphate Anhydrous is the inorganic compound with the formula Na2HPO4.
Disodium Phosphate Anhydrous is one of several sodium phosphates. The salt is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates. All are water-soluble white powders; the anhydrous salt being hygroscopic.
Disodium Phosphate Anhydrous is a reagent with very high buffering capacity.
Disodium Phosphate Anhydrous is widely used in molecular biology, biochemistry and chromatography.
Disodium Phosphate Anhydrous is highly hygroscopic and water soluble. Sodium Phosphate, Dibasic is especially useful in conjunction with Sodium Phosphate, Monobasic (sc-202342, sc-215883 or sc-251042) in the preparation of biological buffers.
Disodium Phosphate Anhydrous can be used in many applications including the purification of antibodies.
Chemical Properties
The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SDisodium Phosphate Anhydrous insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.
Uses
Disodium Phosphate Anhydrous is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers.
Disodium Phosphate Anhydrous is used therapeutically as a cathartic.
Preparation
Disodium Phosphate Anhydrous is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4
About this substance
Helpful information
Disodium Phosphate Anhydrous is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Disodium Phosphate Anhydrous is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
Disodium Phosphate Anhydrous is used in the following products: cosmetics and personal care products, fertilisers, plant protection products and pharmaceuticals.
Other release to the environment of Disodium Phosphate Anhydrous is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Article service life
Other release to the environment of Disodium Phosphate Anhydrous is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Disodium Phosphate Anhydrous can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery) and plastic (e.g. food packaging and storage, toys, mobile phones).
Widespread uses by professional workers
Disodium Phosphate Anhydrous is used in the following products: metal surface treatment products, pH regulators and water treatment products, fertilisers, fillers, putties, plasters, modelling clay, water treatment chemicals and laboratory chemicals.
Disodium Phosphate Anhydrous is used in the following areas: agriculture, forestry and fishing, municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and formulation of mixtures and/or re-packaging.
Disodium Phosphate Anhydrous is used for the manufacture of: metals, fabricated metal products, mineral products (e.g. plasters, cement), textile, leather or fur, pulp, paper and paper products and chemicals.
Other release to the environment of Disodium Phosphate Anhydrous is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Formulation or re-packing
Disodium Phosphate Anhydrous is used in the following products: pH regulators and water treatment products, pharmaceuticals, cosmetics and personal care products, fillers, putties, plasters, modelling clay, fertilisers, metal surface treatment products, water treatment chemicals, leather treatment products and metal working fluids.
Release to the environment of Disodium Phosphate Anhydrous can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance and in the production of articles.
Other release to the environment of Disodium Phosphate Anhydrous is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Uses at industrial sites
Disodium Phosphate Anhydrous is used in the following products: pH regulators and water treatment products, metal surface treatment products, water treatment chemicals, fertilisers, leather treatment products and metal working fluids.
Disodium Phosphate Anhydrous is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and formulation of mixtures and/or re-packaging.
Disodium Phosphate Anhydrous is used for the manufacture of: chemicals, metals, fabricated metal products, textile, leather or fur, pulp, paper and paper products, plastic products and mineral products (e.g. plasters, cement).
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, of substances in closed systems with minimal release and as processing aid.
Manufacture
Release to the environment of Disodium Phosphate Anhydrous can occur from industrial use: manufacturing of the substance and formulation of mixtures.
IUPAC names
Agent FG14
CAS: 7758-79-4
Di Sodium Hydrogen Phosphate
di-Sodio Hidrógeno Fosfato 12-hidrato
di-Sodium hydrogen phosphate
di-Sodium hydrogen phosphate 12-hydrate
disodium hydrogen orthophosphate
Disodium hydrogen phosphate
disodium hydrogen phosphate
DISODIUM HYDROGENORTHOPHOSPHATE
Disodium hydrogenorthophosphate
disodium hydrogenorthophosphate
Disodium hydrogenorthophosphate
disodium hydrogenorthophosphate
Disodium hydrogenorthophosphate heptahydrate
disodium hydrogenphosphate
Disodium orthophosphate dihydrate
DISODIUM PHOSPHATE
Disodium Phosphate
Disodium phosphate
disodium phosphate
Disodium Phosphate, Dibasic Sodium Phosphate
Disodium phosphate, Sodium hydrogen phosphate
disodium;hydrogen phosphate
Disodiumhydrogenphosphate
DSP
Phosphoric acid, disodium salt
sec-Sodium phosphate, Disodium hydrogen phosphate, Disodium phosphate, Sodium hydrogenphosphate, Sodium phosphate dibasic
Sodium hydrogen phosphate
Sodium Phosphate Dibasic
Sodium phosphate dibasic
sodium phosphoric acid
SYNONYMS:
231-448-7 [EINECS]
7558-79-4 [RN]
anhydrousdibasicsodium phosphate
Dinatriumhydrogenphosphat [German] [ACD/IUPAC Name]
Disodium hydrogen phosphate [ACD/IUPAC Name]
Disodium hydrogenorthophosphate
disodium hydrogenphosphate
Disodium phosphate [Wiki]
Disodiumhydrogenorthophosphate
Hydrogénophosphate de disodium [French] [ACD/IUPAC Name]
MFCD00003496 [MDL number]
Na2HPO4 [Formula]
Phosphoric acid disodium salt
secondary Sodium phosphate
sodium hydrogen phosphate (2:1:1)
Sodium hydrogenphosphate
Sodium monohydrogen phosphate
Sodium phosphate dibasic
Sodium Phosphate dibasic anhydrous
BUFFER CONCENTRATE I FROM DI-SODIUM HYDROGEN PHOSPHATE
BUFFER CONCENTRATE II FROM DI-SODIUM HYDROGEN PHOSPHATE
BUFFER SOLUTION
BUFFER SOLUTION, PH 2.5
BUFFER SOLUTION, PH 7.0
DIBASIC SODIUM PHOSPHATE
DINATRII PHOSPHAS ANHYDRICUS
DINATRII PHOSPHAS DIHYDRICUS
DI-SODIUM HYDROGEN ORTHOPHOSPHATE
DI-SODIUM HYDROGEN ORTHOPHOSPHATE 2H2O
DI-SODIUM HYDROGEN ORTHOPHOSPHATE 2-HYDRATE
DI-SODIUM HYDROGEN ORTHOPHOSPHATE DIBASIC
DI-SODIUM HYDROGEN ORTHOPHOSPHATE DIHYDRATE
DISODIUM HYDROGEN PHOSPHATE
DI-SODIUM HYDROGEN PHOSPHATE 2H2O
DI-SODIUM HYDROGEN PHOSPHATE-2-HYDRATE
DI-SODIUM HYDROGEN PHOSPHATE CONCENTRATE I
DI-SODIUM HYDROGEN PHOSPHATE CONCENTRATE II
DI-SODIUM HYDROGEN PHOSPHATE DIHYDRATE
