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Disodium salt is an inorganic sodium salt with the formula Na2S2O3 composed of a 2:1 mixture of sodium and thiosulfate ions.
Disodium salt appears as a bright white colourless crystal or even in powder form.
Disodium salt is used in gold mining, water treatment, analytical chemistry, the development of silver-based photographic film and prints, and medicine.
CAS Number: 7772-98-7
EC Number: 231-867-5
Chemical Formula: Na2S2O3
Molar Mass: 158.11 g/mol
Disodium salt is an inorganic compound with the formula Na2S2O3·xH2O, where x indicates the number of water molecules in Disodium salt.
Typically Disodium salt is available as the white or colorless pentahydrate, Na2S2O3·5H2O.
The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water.
Disodium salt is used in gold mining, water treatment, analytical chemistry, the development of silver-based photographic film and prints, and medicine.
The medical uses of Disodium salt include treatment of cyanide poisoning and pityriasis.
Disodium salt is on the World Health Organization's List of Essential Medicines.
Disodium salt also called as thiosulfuric acid or Sodium thiosulfate is an inorganic salt that is also available in the pentahydrates.
Disodium salt has a chemical formula of Na2S2O3.
Disodium salt appears as a bright white colourless crystal or even in powder form.
Disodium salt is known to possess Alkaline nature when decomposed to sulphide and sulfate in the air.
Disodium salt readily dissolves in water giving thiosulfate ions, one of the useful reducing agents.
The Copper (II) sulfate dissolves to give the cupric ion; in regard to a redox reaction with the thiosulfate, the cupric particles act like oxidizing agents.
Disodium salt is an inorganic sodium salt composed of sodium and thiosulfate ions in a 2:1 ratio.
Disodium salt has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug.
Disodium salt contains a thiosulfate(2-).
Disodium salt is an industrial chemical which also has a long medical history.
Disodium salt was originally used as an intravenous medication for metal poisoning.
Disodium salt has since been approved for the treatment of certain rare medical conditions.
These include cyanide poisoning, calciphylaxis, and cisplatin toxicity.
In vitro assays have demonstrated that Disodium salt is an anti-inflammatory and neuroprotective agent.
Disodium salt therefore has potential for treating neurodegenerative diseases such as Alzheimer disease and Parkinson disease.
NaSH has similar properties and is somewhat more powerful than Disodium salt in these in vitro assays.
However Disodium salt has already been approved as an orally available treatment.
Disodium salt may therefore be a readily available candidate for treating neurodegenerative disorders such as Alzheimer disease and Parkinson disease.
Disodium salt is an industrial compound which has a long history of medical use.
Since Disodium salt is employed as a food preservative, the general population is widely exposed to this non-toxic compound.
For example, Disodium salt is typically added to table salt at less than 0.1% and to alcoholic beverages at less than 0.0005%.
Disodium salt is generally available as a non-prescription oral product.
Disodium salt is an inorganic sodium salt with the formula Na2S2O3 composed of a 2:1 mixture of sodium and thiosulfate ions.
The uses of Disodium salt are numerous, in particular as a fixing agent or to neutralize the effect of biocides such as dichlor, iodine and other oxidants, also, Disodium salt has a role as an antidote to cyanide poisoning, nephroprotective agent and antifungal.
Disodium salt is usually added to table salt at less than 0.1% and to alcoholic beverages at less than 0.0005%.
Disodium salt is usually available as an oral product without a prescription.
Disodium salt solutions are almost exclusively used to standardize Iodine solutions or as back-titrants in titrations using Iodine.
Solutions of Disodium salt are most commonly standardized with Potassium Dichromate or Potassium Iodate solutions, which generate Iodine from Iodide.
Starch indicator is typically used.
The reaction with Iodine is:
I3- + 2 S2O32- → 3 I- + S4O62- (Dithionite ion)
Titrations with standard Disodium salt solution are best conducted in the pH 5 - 9 range.
Since this is not always possible, the titrations should be conducted rapidly and with adequate stirring to insure rapid reaction of the Thiosulfate, thus minimizing any acid-accelerated decomposition.
This will also minimize the acid-catalyzed oxidation of Iodide (usually present in a titration involving Thiosulfate) to Iodate, which could lead to decreased accuracy.
Disodium salt solutions are subject to bacterial decomposition and chemical deterioration.
Disodium salt solutions decompose in acid solution resulting in the evolution of Sulfur Dioxide gas and precipitation of elemental Sulfur.
Contact with Carbon Dioxide in the air can produce the acidity leading to this decomposition, which is faster in more dilute Thiosulfate solutions.
Disodium salt, also known as sodium hydrosulfite, is used as an antidote to cyanide poisoning, but several studies have demonstrated that Disodium salt efficacy in some pathological conditions is related to ectopic calcification.
The mechanisms of action, by which Disodium salt exerts Disodium salt inhibitory effect on vascular mineralization, are not yet clear.
Disodium salt has been postulated that Disodium salt: (i) forms with calcium a more soluble complex than calcium phosphate and calcium oxalate, (ii) has antioxidant activity improving endothelial function, (iii) has acidosis properties.
However, O'Neil and Hardcastle demonstrated that the inhibitor effect of Disodium salt seems to be independent on calcium interactions or on pH, but could be due to a direct extracellular effect on calcification induced by cellular injury releasing cell debris and matrix vesicles.
Nevertheless, Disodium salt is used to treat calciphylaxis, kidney stones, uremic vascular calcification and coronary artery calcification.
Recently, intravenous Disodium salt has been used in a young boy with several deleterious mutations in ABCC6, ENPP1 and HBB genes and, over a period of 6 months, calcific stenosis of celiac and mesenteric arteries was not anymore detectable on arterial ultrasonography.
Follow-up evidenced a temporary efficacy of Disodium salt.
Two clinical trials highlight that Disodium salt treatment can be safe and can reduce the rate of coronary artery calcification progression in hemodialysis patients.
Disodium salt may be used to lessen some of the side effects of cisplatin (a cancer medicine).
Disodium salt is also used with another medicine in the emergency treatment of cyanide poisoning.
Disodium salt is also used to reduce the risk of hearing loss in children 1 month of age and older who are receiving medicines (eg, cisplatin) for cancer that have not spread throughout the body.
This medicine is to be given only by or under the immediate supervision of your doctor.
Disodium salt is available in the following dosage forms:
Solution
Applications of Disodium salt:
We find various applications of Disodium salt in different fields such as medicine, photography, gold extraction and many other areas.
The other uses of Disodium salt are below;
Disodium salt is used in the manufacture of patinas
In industries, the chemical is used for the dechlorination of small water bodies like ponds, aquariums, etc
In photography, the chemical is used as a fixing agent to dissolve the silver salts from the negatives
The chemical can be utilized as a cleansing agent when dissolved in a vast quantity of warm water
Disodium salt is well-used as an antidote agent concerning the cyanide poisoning
In the medical field, Disodium salt is employed in the pharmaceutical preparations such as anionic surfactant aiding in dispersion
Apart from the above uses, the chemical substance also finds Disodium salt applications in the water treatment, leather tanning, neutralizing bleach, gold extraction, photographic film processing, and also in chemical heating pads.
Uses of Disodium salt:
Disodium salt is used predominantly in industry. For example, Disodium salt is used to convert dyes to their soluble colorless forms, which are called leuco.
Disodium salt is also used to bleach "wool, cotton, silk, ...soaps, glues, clay, sand, bauxite, and... edible oils, edible fats, and gelatin."
Disodium salt is added in small quantities to ammonium thiosulfate, which is used as a photographic fixing salt.
The hydrated salt is used as an anti-chlorine in bleaching, in wastewater purification, for reduction of dichromate in chromed leather production, and as a solvent for silver chloride in the chloride roasting of silver-containing minerals.
Disodium salt is used in paper bleaching, photography (fixer), silver extraction, dyeing textiles (mordant), and leather manufacturing.
Disodium salt is also used as an antidote for cyanide poisoning and in vet medicine for bloat and ringworm.
The action of Disodium salt is multifactorial since Disodium salt is a chelating agent of divalent cations, which also has antioxidant and vasodilator properties.
Disodium salt is used to treat cyanide poisoning.
Disodium salt is also used to reduce the side effects of the cancer drug cisplatin.
Disodium salt is used to treat, under certain conditions, calciphylaxis, kidney stones, uremic vascular calcification and coronary artery calcification.
Disodium salt would promote the healing of skin ulcerations, especially when treatment with hyperbaric oxygen therapy is applied concurrently.
Disodium salt is added in small amounts to ammonium thiosulfate, which is used as a photographic fixing salt.
Hydrated salt is used as an anti-chlorine in bleaching, Disodium salt simply reacts and forms sodium hydrogen sulfate or sodium bisulfate which is an inactive salt.
Medical uses:
Disodium salt is used in the treatment of cyanide poisoning.
Other uses include topical treatment of ringworm and tinea versicolor and treating some side effects of hemodialysis and chemotherapy.
In September 2022, the U.S. Food and Drug Administration (FDA) approved Disodium salt under the trade name Pedmark to lessen the risk of ototoxicity and hearing loss in infant, child, and adolescent cancer patients receiving the chemotherapy medication cisplatin.
Photographic processing:
Silver halides, e.g., AgBr, typical components of photographic emulsions, dissolve upon treatment with aqueous thiosulfate.
This application as a photographic fixer was discovered by John Herschel.
Disodium salt is used for both film and photographic paper processing; the Disodium salt is known as a photographic fixer, and is often referred to as 'hypo', from the original chemical name, hyposulphite of soda.
Ammonium thiosulfate is typically preferred to Disodium salt for this application.
Neutralizing chlorinated water:
Disodium salt is used to dechlorinate tap water including lowering chlorine levels for use in aquariums, swimming pools, and spas (e.g., following superchlorination) and within water treatment plants to treat settled backwash water prior to release into rivers.
The reduction reaction is analogous to the iodine reduction reaction.
In pH testing of bleach substances, Disodium salt neutralizes the color-removing effects of bleach and allows one to test the pH of bleach solutions with liquid indicators.
The relevant reaction is akin to the iodine reaction: thiosulfate reduces the hypochlorite (the active ingredient in bleach) and in so doing becomes oxidized to sulfate.
The complete reaction is:
4 NaClO + Na2S2O3 + 2 NaOH → 4 NaCl + 2 Na2SO4 + H2O
Similarly, Disodium salt reacts with bromine, removing the free bromine from the solution.
Solutions of Disodium salt are commonly used as a precaution in chemistry laboratories when working with bromine and for the safe disposal of bromine, iodine, or other strong oxidizers.
Industry Uses:
Agricultural chemicals (non-pesticidal)
Chain transfer agent
Cleaning agent
Corrosion inhibitor
Intermediate
Intermediates
Laboratory chemicals
Not Known or Reasonably Ascertainable
Other (specify)
Oxidizing/reducing agents
Processing aids not otherwise specified
Processing aids, not otherwise listed
Processing aids, specific to petroleum production
Reducing agent
Solids separation agents
Solvents (for cleaning or degreasing)
Surface modifier
Tanning agents not otherwise specified
Consumer Uses:
Cleaning agent
Not Known or Reasonably Ascertainable
Processing aids, not otherwise listed
Solvents (for cleaning or degreasing)
Industrial Processes with risk of exposure:
Pulp and Paper Processing
Sewer and Wastewater Treatment
Leather Tanning and Processing
Photographic Processing
Textiles (Printing, Dyeing, or Finishing)
Metal Extraction and Refining
Activities with risk of exposure:
Applying metallic patinas
Properties of Disodium salt:
Disodium salt is a colorless monoclinic crystal or white crystalline powder, odorless and salty.
The relative density for this is 1.667.
Water-soluble, Disodium salt solubility at 100°C is 231 g/100 ml of vapour.
Disodium salt salt decomposes at high temperatures to give sodium sulfate with sodium polysulfide.
Disodium salt dissociates in water and some other polar solvents.
When exposed to dilute acids such as dilute hydrochloric acid, Disodium salt salt undergoes a decomposition reaction to yield sulfur with sulfur dioxide.
Disodium salt possesses various chemical and physical properties as given below;
Disodium salt appears as a white translucent colourless crystal and is an inorganic compound.
Disodium salt is water-soluble substance and is also soluble in oil of turpentine but not in the alcohol.
Disodium salt has a melting point of about 48 to 52 C.
Disodium salt is highly stable in nature and is said to be incompatible with some strong oxidizing agents and strong acids.
Thiosulfate anion readily reacts with the dilute acids producing sulphur, sulphur dioxide and also water.
The chemical has a density measuring about 1.667 g/mL.
Structure of Disodium salt:
Two polymorphs are known as pentahydrate.
The anhydrous salt exists in several polymorphs.
In the solid state, the thiosulfate anion is tetrahedral in shape and is notionally derived by replacing one of the oxygen atoms by a sulfur atom in a sulfate anion.
The S-S distance indicates a single bond, implying that the terminal sulfur holds a significant negative charge and the S-O interactions have more double-bond character.
Disodium salt has a chemical formula of Na2S2O3 and the molar mass of about 158.11 g/mol.
Disodium salt well exists in the form of pentahydrate salts (Na2S2O3.5H2O), having a molar mass measuring about 248.18 g/mol.
The Disodium salt is an ionic compound which consists of two cations of sodium atom (Na+) and a negatively charged anion of thiosulfate (S2O3-).
Here the central atom consisting of sulphur bonds to the three oxygen atoms and also another atom of sulphur, all these through a single and also double bonds possessing resonance character.
The solid also exists in a monoclinic crystalline structure.
The thiosulfate anion is usually a tetrahedral structure and, is obtained by the replacement of one of the atoms of oxygen by the use of sulfur atom in the sulfate anion.
Manufacturing Methods of Disodium salt:
By-product liquor from sodium sulfide production is reacted with sulfur dioxide to yield Disodium salt; or organic nitro compounds are boiled with sodium polysulfide solution to yield a leach liquor of Disodium salt, which is then purified, concentrated and crystallized
By dissolving sulfur in sodium sulfite soln & then crystallizing.
Disodium salt is also prepared from waste liquors obtained in prodn of sodium sulfide, liquors containing sodium carbonate & small amt of sodium sulfite & sodium sulfate in addn to sulfide.
General Manufacturing Information of Disodium salt:
Industry Processing Sectors:
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Fabricated Metal Product Manufacturing
Machinery Manufacturing
Mining (except Oil and Gas) and support activities
Miscellaneous Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Paper Manufacturing
Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Petrochemical Manufacturing
Petroleum Refineries
Photographic Film, Paper, Plate, and Chemical Manufacturing
Services
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Synthetic Dye and Pigment Manufacturing
Textiles, apparel, and leather manufacturing
Transportation Equipment Manufacturing
Utilities
Wholesale and Retail Trade
Production of Disodium salt:
On an industrial scale, Disodium salt is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture.
In the laboratory, this salt can be prepared by heating an aqueous solution of sodium sulfite with sulfur or by boiling aqueous sodium hydroxide and sulfur according to this equation:
6 NaOH + 4 S → 2 Na2S + Na2S2O3 + 3 H2O
Principal reactions of Disodium salt:
Upon heating to 300 °C, Disodium salt decomposes to sodium sulfate and sodium polysulfide:
4 Na2S2O3 → 3 Na2SO4 + Na2S5
Thiosulfate salts characteristically decompose upon treatment with acids.
Initial protonation occurs at sulfur.
When the protonation is conducted in diethyl ether at −78 °C, H2S2O3 (thiosulfuric acid) can be obtained.
Disodium salt is a somewhat strong acid with pKas of 0.6 and 1.7 for the first and second dissociations, respectively.
Under normal conditions, acidification of solutions of this salt excess with even dilute acids results in complete decomposition to sulfur, sulfur dioxide, and water:
8 Na2S2O3 + 16 HCl → 16 NaCl + S8 + 8 SO2 + 8 H2O
Coordination chemistry:
Thiosulfate is a potent ligand for soft metal ions.
A typical complex is [Pd(S2O3)2(ethylenediamine)]2−, which features a pair of S-bonded thiosulfate ligands.
Disodium salt and ammonium thiosulfate have been proposed as alternative lixiviants to cyanide for extraction of gold.
The advantages of this approach are that (i) thiosulfate is far less toxic than cyanide and (ii) that ore types that are refractory to gold cyanidation (e.g. carbonaceous or Carlin-type ores) can be leached by thiosulfate.
Some problems with this alternative process include the high consumption of thiosulfate, and the lack of a suitable recovery technique, since [Au(S2O3)2]3− does not adsorb to activated carbon, which is the standard technique used in gold cyanidation to separate the gold complex from the ore slurry.
Iodometry:
In analytical chemistry, the most important use comes because the thiosulfate anion reacts stoichiometrically with iodine in aqueous solution, reducing Disodium salt to iodide as the thiosulfate is oxidized to tetrathionate:
2 S2O2−3 + I2 → S4O2−6 + 2 I−
Due to the quantitative nature of this reaction, as well as because Na2S2O3·5H2O has an excellent shelf-life, Disodium salt is used as a titrant in iodometry.
Na2S2O3·5H2O is also a component of iodine clock experiments.
This particular use can be set up to measure the oxygen content of water through a long series of reactions in the Winkler test for dissolved oxygen.
Disodium salt is also used in estimating volumetrically the concentrations of certain compounds in solution (hydrogen peroxide, for instance) and in estimating the chlorine content in commercial bleaching powder and water.
Aluminium cation reaction:
Disodium salt is used in analytical chemistry.
Disodium salt can, when heated with a sample containing aluminium cations, produce a white precipitate:
2 Al3+ + 3 S2O2−3 + 3 H2O → 3 SO2 + 3 S + 2 Al(OH)3
Organic chemistry:
Alkylation of Disodium salt gives S-alkylthiosulfates, which are called Bunte salts.
The alkylthiosulfates are susceptible to hydrolysis, affording the thiol.
This reaction is illustrated by one synthesis of thioglycolic acid:
ClCH2CO2H + Na2S2O3 → Na[O3S2CH2CO2H] + NaCl
Na[O3S2CH2CO2H] + H2O → HSCH2CO2H + NaHSO4
Pharmacology and Biochemistry of Disodium salt:
MeSH Pharmacological Classification:
Chelating Agents:
Chemicals that bind to and remove ions from solutions.
Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.
Antioxidants:
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions.
They counteract the damaging effects of oxidation in animal tissues.
Antitubercular Agents:
Drugs used in the treatment of tuberculosis.
They are divided into two main classes:
"First-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Stability and Reactivity of Disodium salt:
Reactivity:
Not normally reactive
Chemical Stability:
Normally stable.
Possibility of Hazardous Reactions:
Reacts with acids to form toxic and irritating sulfur dioxide gas.
Reacts with strong oxidizers to cause vigorous exothermic reactions.
Conditions to Avoid:
Avoid elevated temperatures.
Incompatibilities:
Strong oxidizers:
Causes vigorous exothermic reactions.
Acids:
Releases sulfur dioxide and/or hydrogen sulfide gas.
Hazardous Decomposition Products:
Sulfur dioxide gas, hydrogen sulfide gas and sodium sulfide residue.
Handling and Storage of Disodium salt:
Precautions For Safe Handling:
Avoid contact with skin, eyes and clothing.
Do not breathe dust or mist.
Use with adequate ventilation.
Wash thoroughly after handling.
If dissolving and mixing solutions:
With anhydrous material, the reaction is exothermic and the solution will retain heat; with the hydrate (crystal) material, the reaction is endothermic and the solution will cool.
Conditions For Safe Storage, Including Any Incompatibilities:
Store in a cool, dry, well-ventilated area away from acids and oxidizing agents.
Keep container closed when not in use and protect from physical damage.
First Aid Measures of Disodium salt:
SKIN:
Wash skin with plenty of soap and water.
Get medical attention if irritation persists.
Launder contaminated clothing before reuse.
EYES:
Flush eyes immediately with water for at least 15 minutes.
Remove contact lenses if present after the first 5 minutes if you can do so easily and continue flushing.
Get medical attention if irritation occurs and persists.
INHALATION:
Promptly remove to fresh air.
Get immediate medical attention if signs of suffocation, irritation or other symptoms develop.
INGESTION:
If conscious, immediately rinse mouth with water and give 1 glass of water to drink.
Do not induce vomiting unless directed to do so be medical personnel.
Get immediate medical attention.
MOST IMPORTANT SYMPTOMS/EFFECTS, ACUTE AND DELAYED:
May irritate the skin.
May cause irritation to the eyes.
May irritate the respiratory tract.
Reacts with acids to form toxic and irritating sulfur dioxide gas.
INDICATION OF IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT, IF NEEDED:
Treat symptomatically.
Fire Fighting Measures of Disodium salt:
Suitable (And Unsuitable) Extinguishing Media:
Material is not flammable.
Use extinguishing media appropriate for material in surrounding fire.
Special Protective Equipment And Precautions For Fire-fighting:
Wear NIOSH-approved self-contained breathing apparatus to protect against any release of toxic and/or irritating fumes.
Skin and eye protection should also be provided.
Use water-spray to keep fire-exposed containers cool, and to knock down vapors and gases.
Accidental Release Measures of Disodium salt:
Personal Precautions, Protective Equipment, And Emergency Procedures:
Wear appropriate personal protective equipment.
Environmental Precautions:
Spills and releases may have to be reported to Federal and/or local authorities.
Methods And Materials For Containment And Cleaning Up:
Promptly sweep up material with minimum dusting and shovel into an empty container with a cover.
Clean spill area with plenty of water.
Identifiers of Disodium salt:
CAS Number:
7772-98-7
(pentahydrate): 10102-17-7
ChEBI: CHEBI:132112
ChEMBL: (pentahydrate): ChEMBL2096650
ChemSpider: 22885
ECHA InfoCard: 100.028.970
EC Number: 231-867-5
E number: E539 (acidity regulators, ...)
PubChem CID: 24477
RTECS number: XN6476000
UNII:
L0IYT1O31N
(pentahydrate): HX1032V43M
CompTox Dashboard (EPA): DTXSID9042417
InChI: InChI=1S/2Na.H2O3S2/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
Key:
AKHNMLFCWUSKQB-UHFFFAOYSA-L
InChI=1/2Na.H2O3S2/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
Key:
AKHNMLFCWUSKQB-NUQVWONBAM
(pentahydrate): InChI=1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2
Key: PODWXQQNRWNDGD-UHFFFAOYSA-L
SMILES:
[Na+].[Na+].[O-]S([O-])(=O)=S
(pentahydrate): O.O.O.O.O.O=S([O-])([O-])=S.[Na+].[Na+]
CAS: 10102-17-7, 7732-18-5
Molecular Formula: H10Na2O8S2
Molecular Weight (g/mol): 248.172
InChI Key: PODWXQQNRWNDGD-UHFFFAOYSA-L
PubChem CID: 61475
ChEBI: CHEBI:32150
IUPAC Name: disodium;dioxido-oxo-sulfanylidene-$l^{6}-sulfane;pentahydrate
SMILES: O.O.O.O.O.[O-]S(=O)(=S)[O-].[Na+].[Na+]
CAS number: 7772-98-7
EC number: 231-867-5
Hill Formula: Na₂O₃S₂
Molar Mass: 158.10 g/mol
HS Code: 2832 30 00
Quality Level: MQ200
Synonyms: Sodium thiosulfate
Linear Formula: Na2S2O3
CAS Number: 7772-98-7
Molecular Weight: 158.11
Properties of Disodium salt:
Chemical formula: Na2S2O3
Molar mass: 158.11 g/mol (anhydrous)
248.18 g/mol (pentahydrate)
Appearance: White crystals
Odor: Odorless
Density: 1.667 g/cm3
Melting point: 48.3 °C (118.9 °F; 321.4 K) (pentahydrate)
Boiling point: 100 °C (212 °F; 373 K) (pentahydrate, - 5H2O decomposition)
Solubility in water: 70.1 g/100 mL (20 °C)
231 g/100 mL (100 °C)
Solubility: negligible in alcohol
Refractive index (nD): 1.489
Density: 1.667 g/cm3 (20 °C)
Melting Point: 48 °C
pH value: 6.0 - 9.5 (50 g/l, H₂O, 20 °C)
Bulk density: 1350 kg/m3
Solubility: 701 g/l
Molecular Weight: 158.11 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 157.90842477 g/mol
Monoisotopic Mass: 157.90842477 g/mol
Topological Polar Surface Area: 104Ų
Heavy Atom Count: 7
Complexity: 82.6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Specifications of Disodium salt:
Assay (iodometric): ≥ 97.0 %
Identity: passes test
pH-value (5 %; water): 6.0 - 9.5
Sulphide (S): ≤ 0.002 %
Fe (Iron): ≤ 0.005 %
Heavy metals (as Pb): ≤ 0.005 %
Boiling Point: 100°C
Melting Point: 48.3°C
Physical Form: Liquid
Quantity: 1 L
Solubility Information: Soluble in water
Formula Weight: 248.18g/mol
Concentration or Composition (by Analyte or Components): 0.1mol/L
Density: 1.00g/mL
Chemical Name or Material: Sodium Thiosulfate Pentahydrate
Structure of Disodium salt:
Crystal structure: monoclinic
Related compounds of Disodium salt:
Other cations:
Thiosulfuric acid
Lithium thiosulfate
Potassium thiosulfate
Names of Disodium salt:
IUPAC name:
Sodium thiosulfate
Other names:
Sodium hyposulphite
Hyposulphite of soda
Hypo
Synonyms of Disodium salt:
SODIUM THIOSULFATE
7772-98-7
sodiumthiosulfate
Disodium thiosulfate
Hypo
Chlorine Control
Thiosulfuric acid, disodium salt
Sodium thiosulfate, anhydrous
disodium sulfurothioate
MFCD00003499
Na2S2O3
L0IYT1O31N
Thiosulfuric acid (H2S2O3), disodium salt
Sodothiol
sodium sulfothioate
Sodothiol; Sulfactol; Sulfothiorine
Chlorine Cure
Declor-It
Hypo (VAN)
HSDB 592
EINECS 231-867-5
Na2O3S2
UNII-L0IYT1O31N
AI3-01237
sodium thiosulfat
sodium thio-sulfate
Sodium oxide sulfide
Hypo alcohol, in ethanol
anhydrous sodium thiosulfate
EC 231-867-5
DISODIUM THIOSULPHATE
sodium thiosulfate (anhydrous)
SODIUM THIOSULFATE [MI]
CHEMBL3753202
DTXSID9042417
SODIUM THIOSULFATE [HSDB]
CHEBI:132112
Sodium thiosulfate, AR, >=98%
Sodium thiosulfate, LR, >=97%
SODIUM THIOSULFATE [WHO-DD]
Sodium thiosulfate, p.a., 98.0%
AKOS015856704
AKOS016372312
SODIUM THIOSULFATE ANHYDROUS [II]
BP-21059
Sodium thiosulfate, ReagentPlus(R), 99%
FT-0696570
O0522
D78333
Sodium thiosulfate, SAJ first grade, >=90.0%
disodium;dioxido-oxo-sulfanylidene-lambda6-sulfane
Q339866
Sodium thiosulfate, >=99.99% trace metals basis
Sodium thiosulfate, Vetec(TM) reagent grade, 99%
Thiosulfuric acid (H2S2O3), sodium salt (1:2)
Sodium thiosulfate, anhydrous, Trace metals grade 99.99%
Sodium thiosulfate, purum p.a., anhydrous, >=98.0% (RT)
Sodium thiosulfate [JAN] [USAN] [Wiki]
Sodium hyposulfite
231-791-2 [EINECS]
231-867-5 [EINECS]
7772-98-7 [RN]
Dinatriumsulfurothioat [German] [ACD/IUPAC Name]
Disodium sulfurothioate [ACD/IUPAC Name]
Disodium thiosulfate
Hypo alcohol
MFCD00003499 [MDL number]
sodium thiosulphate
Sulfurothioate de disodium [French] [ACD/IUPAC Name]
Thiosulfuric acid disodium salt
Thiosulfuric acid, disodium salt
anhydrous sodium thiosulfate
antichlor
Declor-It
disodium sulfanesulfite
DISODIUM SULFANIDESULFONATE
DISODIUM THIOSULPHATE
disodium;dioxido-oxo-sulfanylidene-λ6-sulfane
Hypo
S-Hydril
sodium oxide sulfide
Sodium oxide sulfide (Na2S2O3 )
Sodium thiosulfate (Na2 S2 O3 )
Sodium thiosulfatemissing
Sodothiol
Sulfothiorine
