Quick Search
E1518 Triacetin, also known as glyceryl triacetate, is a colorless, odorless, and viscous liquid that serves as a triester of glycerol and acetic acid.
E1518 Triacetin's chemical formula is C9H14O5, and it is characterized by its high solubility in organic solvents and low solubility in water.
E1518 Triacetin is commonly used as a plasticizer in the production of plastics and as a solvent in various applications, including food and pharmaceuticals.
CAS: 102-76-1
MF: C9H14O6
MW: 218.2
EINECS: 203-051-9
Synonyms
TRIACETIN;TRIACETIN (C2:0);Triacetyl glycerin;GLYCERIN TRIACETATE;1,3-Diacetyloxypropan-2-yl acetate;propane-1,2,3-triyl triethanoate;Glyceryl triacetate,1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glycerol triacetate, Triacetin;Triacetin, 99%, extra pure, Ph Eur, USP, BP
E1518 Triacetin is recognized for its ability to enhance the flexibility and durability of materials.
Additionally, E1518 Triacetin is utilized in the food industry as a flavoring agent and humectant, contributing to moisture retention in food products.
E1518 Triacetin's low toxicity profile makes it suitable for use in consumer products.
In terms of stability, E1518 Triacetin is relatively stable under normal conditions but can undergo hydrolysis in the presence of water and heat, leading to the formation of glycerol and acetic acid.
Overall, E1518 Triacetin is valued for its multifunctional properties across various industrial and commercial applications.
E1518 Triacetin, also known as 1,2,3-propanetriol triacetate or glyceryl triacetate, is the triester of glycerin and acetic acid.
E1518 Triacetin can be prepared by heating glycerin with acetic anhydride alone or in the presence of finely divided potassium hydrogen sulfate.
E1518 Triacetin can also be prepared by the reaction of oxygen with a liquid-phase mixture of allyl acetate and acetic acid using a bromide salt as a catalyst.
E1518 Triacetin is the organic compound with the formula C3H5(OCOCH3)3.
E1518 Triacetin is classified as a triglyceride, i.e., the triester of glycerol with acetic acid.
E1518 Triacetin is a colorless, viscous, and odorless liquid with a high boiling point and a low melting point.
E1518 Triacetin has a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations.
E1518 Triacetin is one of the glycerine acetate compounds.
Triacetin is an excipient used in pharmaceutical formulations.
E1518 Triacetin is a triglyceride that acts as a plasticizer, solvent, and humectant in various pharmaceutical products, enhancing the consistency and stability of the formulations.
Triacetin is the triester of glycerol.
E1518 Triacetin is a colorless, viscous and odorless liquid at room temperature. Triacetin is used in food and cosmetic products.
E1518 Triacetin’s high solvency power and high volatility make it a good solvent and fixative for flavors and fragrances.
Two grades are available: 99,5% purity for flavor & fragrance and a technical grade for industrial applications.
E1518 Triacetin is an organic compound with the molecular formula C9H14O6 and CAS 102-76-1.
E1518 Triacetin is a colorless and odorless oily liquid with a light fruity and sweet meaty aroma, and a slight bitterness at low concentrations.
Can be miscible with organic solvents such as ethanol, ether, benzene, chloroform, etc., soluble in acetone, insoluble in mineral oil.
Slightly soluble in water, with a solubility of 5.9g/100ml at 25 ℃.
Soluble in ethanol, ether, benzene, chloroform, and castor oil, insoluble in flaxseed oil.
E1518 Triacetin can dissolve nitrocellulose, cellulose acetate, acrylic resin, polyvinyl acetate, etc.
E1518 Triacetin also has a certain dissolving effect on natural rosin, but it is not miscible with polyvinyl chloride, polystyrene, and chlorinated rubber.
E1518 Triacetin can be used in daily chemical essence formula, mainly as fixative.
E1518 Triacetin Chemical Properties
Melting point: 3 °C(lit.)
Boiling point: 258-260 °C(lit.)
density: 1.16 g/mL at 25 °C(lit.)
vapor density: 7.52 (vs air)
vapor pressure: 0.00248 mm Hg @ 250C
refractive index: n25/D 1.429-1.431(lit.)
FEMA: 2007 | (TRI-)ACETIN
Fp: 300 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in water, miscible with ethanol (96 per cent) and toluene.
form: Liquid
color: Clear colorless
PH: 5.0-6.0 (20°C, 50g/L in H2O)
Odor: Characteristic odour
explosive limit: 1.05%, 189°F
biological source: synthetic
Odor Type: fruity
Water Solubility: 64.0 g/L (20 ºC)
Merck: 14,9589
JECFA Number: 920
BRN: 1792353
Henry's Law Constant: 8.0×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Dielectric constant: 7.2（20℃）
Stability: Stable. Incompatible with strong oxidizing agents. Combustible.
Major Application: flavors and fragrances
Cosmetics Ingredients Functions: PLASTICISER SOLVENT FILM FORMING FRAGRANCE ANTIMICROBIAL
InChI: 1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3
InChIKey: URAYPUMNDPQOKB-UHFFFAOYSA-N
LogP: 0.25
CAS DataBase Reference: 102-76-1(CAS DataBase Reference)
NIST Chemistry Reference: E1518 Triacetin(102-76-1)
EPA Substance Registry System: E1518 Triacetin (102-76-1)
Uses
As a plasticizer and fragrance fixative, ink solvent, also used in medicine and dye synthesis.
As a chromatographic fixative, solvent, toughener and fragrance fixative.
Humectants; carrier solvents; plasticizers; E1518 Triacetin can absorb carbon dioxide from the natural gas.
In the production of cosmetics, pharmaceuticals and dyes, plasticizers for cigarette filter rods, and so on.
Applied in cosmetics, casting, medicine, dyes and other industries.
E1518 Triacetin is non-toxic, non-irritating.
As the substrate for the determination of lipase, perfume fixative, solvent, gas chromatographic fixative (maximum temperature of 85 ℃, solvent: methanol, chloroform), separation of gas and aldehyde analysis.
E1518 Triacetin is a common food additive, for instance as a solvent in flavorings, and for its humectant function, with E number E1518 and Australian approval code A1518.
E1518 Triacetin is used as an excipient in pharmaceutical products, where it is used as a humectant, a plasticizer, and as a solvent.
Potential uses
The plasticizing capabilities of E1518 Triacetin have been utilized in the synthesis of a biodegradable phospholipid gel system for the dissemination of the cancer drug paclitaxel (PTX).
In the study, E1518 Triacetin was combined with PTX, ethanol, a phospholipid and a medium chain triglyceride to form a gel-drug complex.
This complex was then injected directly into the cancer cells of glioma-bearing mice.
The gel slowly degraded and facilitated sustained release of PTX into the targeted glioma cells.
E1518 Triacetin can also be used as a fuel additive as an antiknock agent for gasoline, and to improve low-temperature viscosity properties of biodiesel.
E1518 Triacetin has been considered as a possible source of food energy in artificial food regeneration systems on long space missions.
E1518 Triacetin is believed to be safe to get over half of one's dietary energy from triacetin.
