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E333 Calcium Citrates are calcium salts of citric acid used in food and beverage applications as acidity regulators, buffering agents, chelating agents, and calcium sources, and E333 Calcium Citrates are valued for providing calcium with good compatibility in many formulations.
E333 Calcium Citrates help control acidity by forming citrate buffer systems with citric acid and by binding metal ions, and E333 Calcium Citrates are used to stabilize flavor, improve processing tolerance, and support consistent product quality in many foods.
E333 Calcium Citrates are typically supplied as white powders in different hydrate forms and salt types, and E333 Calcium Citrates performance depends on the specific citrate form, solubility behavior, dosage, and the overall acid-salt balance in the formulation.
CAS Number: 813-94-5 (Calcium citrate, common) / 5785-44-4 (Calcium citrate tetrahydrate, common)
EC Number: 212-391-7 (calcium citrate, common)
Molecular Formula: Ca3(C6H5O7)2 (common representation) / Ca3(C6H5O7)2·4H2O (tetrahydrate, common)
Molecular Weight: 498.43 g/mol (anhydrous, common representation) / 570.49 g/mol (tetrahydrate, common)
Synonyms: E333 Calcium Citrates, Calcium Citrate, Tricalcium Citrate, Calcium Citrate Tetrahydrate, Calcium Citrate Food Grade, Calcium Citrate Buffer, Calcium Citrate Chelating Agent, E333, Calcium Citrates Acidity Regulator, Calcium Citrates pH Buffer, Calcium Salt of Citric Acid, Calcium Citrate Fortification Salt, E333 Calcium Citrates, Calcium Citrates, Calcium Citrate, Tricalcium Citrate, Tricalcium Dicitrate, Tricalcium 2-Hydroxypropane-1,2,3-tricarboxylate, Tricalcium 2-Hydroxy-1,2,3-propanetricarboxylate, Citric Acid Calcium Salts, Calcium Salts of Citric Acid, Calcium Citrate Salts, Monocalcium Citrate, Dicalcium Citrate, Tricalcium Citrate Tetrahydrate, Calcium Citrate Tetrahydrate, Calcium Citrate Anhydrous, Calcium Hydrogen Citrate, Dicalcium Hydrogen Citrate, Monocalcium Dihydrogen Citrate, Tricalcium Citrate FCC, Tricalcium Citrate USP, Tricalcium Citrate BP, Tricalcium Citrate EP, Tricalcium Citrate JP, Tricalcium Citrate NF, Calcium Citrate FCC, Calcium Citrate USP, Calcium Citrate BP, Calcium Citrate EP, Calcium Citrate JP, Calcium Citrate NF, Calcium Citrates Food Grade, Calcium Citrates Technical Grade, Calcium Citrates Pharmaceutical Grade, Calcium Citrates Industrial Grade, Calcium Citrates Reagent Grade, Calcium Citrates Analytical Grade, Calcium Citrates Laboratory Grade, Calcium Citrates High Purity, Calcium Citrates Pure, Calcium Citrates Powder
APPLICATIONS
E333 Calcium Citrates are used in calcium-fortified foods and beverages to provide calcium in compatible formulations.
E333 Calcium Citrates are incorporated into powdered beverages to provide mineral fortification with good stability.
E333 Calcium Citrates are used in nutrition products to support calcium claims and mineral balance.
E333 Calcium Citrates are used in dietary supplements and nutraceutical products as a calcium source with good handling in powders and tablets.
E333 Calcium Citrates are incorporated into chewable supplements to provide calcium with acceptable taste in compatible systems.
E333 Calcium Citrates are used in effervescent tablets to provide calcium in compatible acid-base systems.
E333 Calcium Citrates are used in dairy products and dairy desserts to support calcium fortification and maintain pH stability.
E333 Calcium Citrates are incorporated into flavored milk drinks to improve mineral balance and buffering in compatible formulations.
E333 Calcium Citrates are used in processed cheese systems in selected applications to support mineral balance and texture design.
E333 Calcium Citrates are used in jams, jellies, and fruit preparations to control pH and improve gel stability in compatible systems.
E333 Calcium Citrates are incorporated into fruit fillings to reduce excessive sharpness while maintaining target acidity.
E333 Calcium Citrates are used in confectionery to buffer acid systems and improve taste balance.
E333 Calcium Citrates are used in sauces and condiments to stabilize pH and improve flavor consistency over shelf life.
E333 Calcium Citrates are incorporated into salad dressings to provide buffering and chelation support in acid systems.
E333 Calcium Citrates are used in mayonnaise-type products to help manage pH and maintain stable texture.
E333 Calcium Citrates are used as chelating agents to bind metal ions, improving color and flavor stability in sensitive products.
E333 Calcium Citrates are incorporated into beverages to reduce metal-catalyzed oxidation and off-flavor development.
E333 Calcium Citrates are used in oils and emulsions to improve oxidative stability in compatible systems.
E333 Calcium Citrates are used as firming and texture-support ingredients in some fruit and vegetable processing applications.
E333 Calcium Citrates are incorporated into processed fruits to support firmness and reduce softening in compatible designs.
E333 Calcium Citrates are valued because E333 Calcium Citrates provide buffering, chelation, and calcium fortification benefits that support stable flavor, improved processing tolerance, and consistent product quality across many food categories.
E333 Calcium citrates are used in dairy products to support calcium fortification in some formulations.
E333 Calcium citrates support consistent calcium content in yogurts and fermented dairy desserts.
E333 Calcium citrates help maintain smooth texture when properly dispersed.
E333 Calcium citrates are used in plant-based beverages to provide calcium fortification in some formulations.
E333 Calcium citrates support mineral enrichment of oat, soy, and nut beverages.
E333 Calcium citrates help improve nutrition labeling while managing sensory quality.
E333 Calcium citrates are used in bakery products as calcium fortification ingredients in some recipes.
E333 Calcium citrates support mineral enrichment in breads, cakes, and biscuits.
E333 Calcium citrates help improve nutritional labeling while maintaining acceptable taste.
E333 Calcium citrates are used in cereal products and nutrition bars to add calcium in some formulations.
E333 Calcium citrates support calcium fortification in snacks and breakfast items.
E333 Calcium citrates help improve mineral content while keeping processing manageable.
E333 Calcium citrates are used in dietary supplements as calcium sources in tablets, capsules, and powders.
E333 Calcium citrates support calcium delivery in supplement formulations.
E333 Calcium citrates help provide a well-recognized citrate-form calcium option in many markets.
E333 Calcium citrates are used in effervescent tablets and drink mixes as calcium sources in some formulations.
E333 Calcium citrates support mineral contribution while managing acid–base taste balance.
E333 Calcium citrates help improve palatability compared with some mineral salts in effervescent products.
E333 Calcium citrates are used in chewable calcium supplements for improved taste and mouthfeel in some designs.
E333 Calcium citrates support consumer-acceptable flavoring and reduced harsh mineral notes.
E333 Calcium citrates help improve compliance in calcium supplementation products.
E333 Calcium citrates are used in gummies as calcium sources in some supplement products.
E333 Calcium citrates support mineral enrichment while maintaining chew texture.
E333 Calcium citrates help reduce gritty texture when properly formulated.
E333 Calcium citrates are used in confectionery as mineral fortification ingredients in some products.
E333 Calcium citrates support calcium enrichment of candies and chews in some concepts.
E333 Calcium citrates help balance acidity and mineral content in fortified sweets.
E333 Calcium citrates are used as firming support salts in fruit and vegetable processing.
E333 Calcium citrates support calcium crosslinking of pectin in plant tissues.
E333 Calcium citrates help improve firmness and reduce softening in processed produce.
E333 Calcium citrates are used in fresh-cut fruit to maintain firmness and reduce browning in some applications.
E333 Calcium citrates support tissue integrity during refrigerated storage.
E333 Calcium citrates help improve texture of fresh-cut apples, melons, and similar fruits in some systems.
E333 Calcium citrates are used in fresh-cut vegetables to improve crispness and shelf life in some treatments.
E333 Calcium citrates support calcium uptake that strengthens cell wall structure.
E333 Calcium citrates help reduce softening and improves bite in some produce packs.
E333 Calcium citrates are used in pickling and brining to support texture retention in some recipes.
E333 Calcium citrates support firming of pickled cucumbers and other vegetables in some formulations.
E333 Calcium citrates help reduce mushiness while maintaining acceptable flavor.
E333 Calcium citrates are used in jams and fruit spreads to support gelation in some formulations.
E333 Calcium citrates support calcium-activated pectin systems where used.
E333 Calcium citrates help improve set and reduce weeping in some jams.
E333 Calcium citrates are used in bakery fillings and fruit fillings to stabilize texture in some products.
E333 Calcium citrates support pectin gel strength in fruit preparations.
E333 Calcium citrates help reduce syneresis and improve sliceability in fillings.
E333 Calcium citrates are used in dairy desserts to stabilize acidity and mineral balance in some products.
E333 Calcium citrates support controlled tartness in fruit yogurts and dairy gels.
E333 Calcium citrates help stabilize pH and reduce mineral-driven instability in some systems.
E333 Calcium citrates are used in processed cheese and cheese sauces to adjust calcium balance in some formulations.
E333 Calcium citrates support texture tuning and melt behavior in selected systems.
E333 Calcium citrates help maintain stable product body when calcium balance is controlled.
E333 Calcium citrates are used in beverage processing as buffering and sequestrant salts in some formulations.
E333 Calcium citrates support control of pH and complexation in selected systems.
E333 Calcium citrates help reduce instability caused by metal ions in some beverages.
E333 Calcium citrates are used as sequestrants to bind metal ions and improve stability in some foods.
E333 Calcium citrates support reduction of oxidation and off-flavor formation in some formulations.
E333 Calcium citrates help improve stability of flavors and colors by moderating metal-catalyzed reactions.
E333 Calcium citrates are used in pharmaceuticals as calcium sources and citrate salts in some formulations.
E333 Calcium citrates support electrolyte and mineral contribution in oral solutions and solids.
E333 Calcium citrates help maintain formulation stability when compatible.
E333 Calcium citrates are used in medical nutrition products to increase calcium content in some formulas.
E333 Calcium citrates support balanced mineral profiles in specialized nutrition products.
E333 Calcium citrates help improve labeling without excessive chalkiness when designed well.
E333 Calcium citrates are used in oral care products as calcium-containing ingredients in some formulations.
E333 Calcium citrates support mineral presence in mouthwashes and dental gels in some systems.
E333 Calcium citrates help improve product positioning for mineral support in oral products where appropriate.
E333 Calcium citrates are used in cosmetics as mineral salts in some skin care products.
E333 Calcium citrates support formulation electrolyte balance in certain systems.
E333 Calcium citrates help support stability and sensory feel in some products.
E333 Calcium citrates are used in laboratory media as calcium sources for microbial and cell culture in some applications.
E333 Calcium citrates support controlled calcium availability in culture systems.
E333 Calcium citrates help maintain reproducible nutrient conditions in research.
E333 Calcium citrates are used in water treatment and industrial processes to chelate metals and manage hardness in some systems.
E333 Calcium citrates support scale control strategies under defined conditions.
E333 Calcium citrates help stabilize water chemistry in selected industrial applications.
E333 Calcium citrates are used in cleaning products as chelating salts in some formulations.
E333 Calcium citrates support improved detergent performance in hard water.
E333 Calcium citrates help reduce soap scum formation and improve rinse clarity.
E333 Calcium citrates are used in product development to tune calcium level, buffering, and stability in fortified foods.
E333 Calcium citrates support achieving target mineral content with acceptable sensory profile.
E333 Calcium citrates help optimize dispersion and reduce sediment in fortified beverages.
E333 Calcium citrates are used in manufacturing troubleshooting to address sedimentation in fortified beverages.
E333 Calcium citrates support improved mineral dispersion through correct processing and stabilizer selection.
E333 Calcium citrates help reduce gritty texture and settling in finished products.
E333 Calcium citrates are used in quality control to verify calcium content, solubility behavior, and impurity limits.
E333 Calcium citrates support consistent fortification performance across batches.
E333 Calcium citrates help ensure correct labeling and stable finished product outcomes.
E333 Calcium citrates are used in education and training as examples of citrate chemistry, chelation, and mineral fortification.
E333 Calcium citrates support teaching about solubility, complexation, and buffering.
E333 Calcium citrates help illustrate how calcium salts affect taste, stability, and texture.
E333 Calcium citrates are used in export products to support stable mineral fortification during long logistics chains.
E333 Calcium citrates support consistent quality during distribution and storage.
E333 Calcium citrates help reduce returns caused by sedimentation or texture defects when properly formulated.
E333 Calcium citrates are used in R&D to compare calcium salts for solubility, taste, and processing performance.
E333 Calcium citrates support selection of best calcium source for a target product.
E333 Calcium citrates help optimize formulation performance while maintaining acceptable sensory quality.
E333 Calcium citrates are used in chewable antacid-type products in some markets where citrate salts are used for mineral contribution.
E333 Calcium citrates support mild taste profile compared with some alkaline salts in certain formulations.
E333 Calcium citrates help improve consumer acceptance when correctly formulated.
E333 Calcium citrates are used in fortified foods to support calcium claims in approved markets.
E333 Calcium citrates support nutritional positioning and mineral enrichment strategies.
E333 Calcium citrates help maintain product quality while improving nutrient profile.
DESCRIPTION
E333 Calcium Citrates are salts of citric acid, and E333 Calcium Citrates function as buffering agents by balancing citrate and citric acid forms to maintain stable pH.
E333 Calcium Citrates reduce harsh sourness by moderating free acid levels, and this helps improve palatability in beverages and acidic foods.
E333 Calcium Citrates bind metal ions such as iron and copper, and this chelation helps reduce oxidative discoloration and off-flavor development in sensitive products.
E333 Calcium Citrates provide calcium, and this makes E333 Calcium Citrates useful for fortification, but calcium salts can influence clarity and texture at higher dosages, so formulation testing is important.
E333 Calcium Citrates have lower water solubility than sodium or potassium citrates, and solubility depends on hydration state, particle size, and acid balance.
E333 Calcium Citrates should be used according to applicable food additive regulations and good manufacturing practices for the target market.
E333 Calcium Citrates are typically supplied as white powders in different hydrate forms, and grade selection affects solubility, handling, and fortification performance.
E333 Calcium Citrates should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and caking.
E333 Calcium Citrates should be handled with good hygiene and dust control practices during bulk powder processing.
E333 Calcium citrates are calcium salts of citric acid and are used as food additives and calcium sources.
E333 Calcium citrates are typically white powders with limited water solubility compared with some other calcium salts.
E333 Calcium citrates provide calcium ions for fortification and citrate ions that can contribute buffering and chelation effects.
E333 Calcium citrates are widely used in dietary supplements and fortified foods because citrate forms are often perceived as well tolerated.
E333 Calcium citrates can also influence texture in pectin-containing systems by providing calcium for ionic crosslinking.
E333 Calcium citrates can chelate metal ions, which can improve stability of flavors and colors in some formulations.
E333 Calcium citrates performance depends on grade, particle size, hydration state, and dispersion conditions.
E333 Calcium citrates should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and caking.
E333 Calcium citrates are valued for calcium delivery, citrate functionality, and broad usefulness across food and nutrition applications.
PROPERTIES
Chemical Formula: Ca3(C6H5O7)2 (common) / Ca3(C6H5O7)2·4H2O (tetrahydrate)
Molecular Weight: 498.43 g/mol / 570.49 g/mol
Common Name: E333 Calcium Citrates
Chemical Type: Citrate salts; acidity regulator; buffering agent; chelating agent; calcium source
Appearance: White powder
Odor: Odorless
Taste: Mild salty with citrate note; relatively neutral compared with some calcium salts
Solubility: Slightly soluble to moderately soluble in water (grade and pH dependent)
Buffering Range: Effective in acidic to near-neutral pH systems depending on citrate-to-acid ratio
Chelation: Binds metal ions to improve stability and reduce oxidation
Thermal Stability: Stable under typical food processing conditions
Hygroscopicity: Low to moderate (grade dependent)
Storage Temperature: 15–30°C, tightly closed, dry
Shelf Life: Typically 24–60 months in original sealed packaging (supplier dependent)
FIRST AID
Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during powder handling.
Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.
Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a large amount is swallowed.
Never give anything by mouth to an unconscious person.
Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care as needed.
HANDLING AND STORAGE
Handling:
Use appropriate PPE including gloves and safety glasses for bulk handling.
Avoid generating dust and avoid inhalation of fine powder.
Maintain good hygiene and clean-up practices in handling areas.
Ventilation:
Use general ventilation for normal handling.
Use local exhaust where dust may be generated during powder transfer.
Minimize airborne particulate accumulation in enclosed areas.
Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain free-flowing behavior.
Keep containers properly labeled and protected from contamination.
Spill and Leak Procedures:
Sweep up spilled powder and avoid dust generation.
Collect into suitable containers for reuse or disposal according to local regulations.
Clean residues with water if needed and dry the area to prevent slip hazards.
Handling Precautions:
Balance E333 Calcium Citrates with E330 Citric Acid to achieve target pH and buffering behavior because calcium citrate solubility and performance are strongly pH dependent.
Evaluate clarity and texture impact in beverages because calcium salts can increase turbidity at higher dosages.
Rotate stock using FIFO practices to maintain consistent quality and predictable buffering, chelation, and fortification performance.
