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E354 Calcium tartrate is a by product of the wine industry, prepared from wine fermentation dregs.
E354 Calcium tartrate is the calcium salt of tartaric acid, an acid most commonly found in ripe grapes.
E354 Calcium tartrates solubility decreases with colder temperature, which results in the forming of whitish (in red wine often reddish) crystalline clusters as it precipitates.
CAS Number: 3164-34-9
Molecular Formula: C4H8CaO6
Molecular Weight: 192.18
EINECS Number: 221-621-5
Synonyms: O6I5B26XA7, 3164-34-9, INS NO.354, DTXSID50883961, INS-354, Butanedioic acid, 2,3-dihydroxy-(2R,3R)-, calcium salt (1:1), E-354, RefChem:122914, DTXCID301023438, 221-621-5, Calcium tartrate, calcium d-tartrate, Butanedioic acid, 2,3-dihydroxy-(2R,3R)-, calcium salt (1:1), calcium l-tartrate, calcium l-(+)-tartrate, Calcium tartarate, calcium L(+)-tartrate, Calcium (2R,3R)-2,3-dihydroxybutanedioate, calcium L(+)-tartrate, calcium;(2R,3R)-2,3-dihydroxybutanedioate, Tartaric acid, calcium salt, UNII-O6I5B26XA7, CALCIUM TARTRATE [MI], Butanedioic acid, 2,3-dihydroxy-, calcium salt (1:1), (2R,3R)-rel-, CALCIUM TARTRATE [WHO-DD], EINECS 221-621-5, Tartaric acid, calcium salt (1:1), CALCIUM L-(+)-TARTRATE (1:1), 2,3-Dihydroxybutanedioic acid, calcium salt, EC 221-621-5, Q416767, BUTANEDIOIC ACID, 2,3-DIHYDROXY- (R-(R*,R*))-, CALCIUM SALT (1:1), (+)-CALCIUM L-TARTRATE DIHYDRATE;Calciumtartrat;CALCIUM TARTRATE 2-HYDRATE;L-Calciumtartrate;CALICIUMTARTRATE;2,3-dihydroxy-[ theta-( theta, theta)]-butanedioic aci calcium salt;(+)-Calcium L-tartrate hydrate;(2R,3R)-2,3-Dihydroxybutanedioic acid calcium salt
E354 Calcium tartrate finds use as a food preservative and acidity regulator. Like tartaric acid, calcium tartrate has two asymmetric carbons, hence it has two chiral isomers and a non-chiral isomer (meso-form).
E354 Calcium tartrate of biological origin is the chiral levorotatory (–) isomer.
E354 Calcium tartrate, exactly calcium L-tartrate, is a byproduct of the wine industry, prepared from wine fermentation dregs.
It is the calcium salt of L-tartaric acid, an acid most commonly found in grapes.
Its solubility decreases with lower temperature, which results in the forming of whitish (in red wine often reddish) crystalline clusters as it precipitates.
As E354 Calcium tartrate, it finds use as a food preservative and acidity regulator.
E354 Calcium tartrate has two asymmetric carbons, hence it has two chiral isomers and a non-chiral isomer (meso-form).
E354 Calcium tartrate of biological origin is the chiral levorotatory (–) isomer.
E354 Calcium tartrate is the calcium salt of tartaric acid, formed when tartaric acid reacts with calcium ions, and it is used mainly as an acidity regulator, stabilizer, sequestrant (metal-binding agent), and firming agent in food and industrial applications because it helps control pH, stabilize product structure, and bind metal ions that could otherwise affect color, texture, or chemical stability.
It is related to naturally occurring tartrates found in grapes and wine.
This improves stability and processing control.
E354 Calcium tartrate consists of a tartaric acid backbone (a dicarboxylic acid with hydroxyl groups) combined with calcium ions (Ca²⁺), which makes it sparingly soluble in water and effective in forming stable complexes or controlled precipitation systems depending on conditions.
This low solubility is one reason it is used in stabilization processes.
E354 Calcium tartrate improves controlled crystallization and stability behavior.
E354 Calcium tartrate appears as a white crystalline or powdery solid, and it has low solubility in water, meaning it does not dissolve easily but instead remains stable in solid form within formulations or natural systems.
It is stable under normal storage conditions and non-volatile.
E354 Calcium tartrate improves handling and storage stability.
E354 Calcium tartrate acts mainly as a stabilizing and regulating agent, helping control acidity, prevent unwanted precipitation reactions, and stabilize product structure, especially in systems containing natural acids or metal ions.
It is often used where controlled mineral balance is important.
This improves product consistency and chemical control.
E354 Calcium tartrate is best described as a poorly water-soluble calcium salt of tartaric acid used to regulate acidity, stabilize formulations, bind metal ions, and control crystallization processes in food, beverage, pharmaceutical, and industrial systems.
E354 Calcium tartrate is also important in natural crystallization chemistry of fruit systems, because it forms when tartaric acid (naturally present in grapes and other fruits) reacts with calcium ions during ripening, processing, or storage, and this makes it a key compound in understanding how mineral–organic acid interactions affect clarity and stability in fruit-derived products.
E354 Calcium tartrates formation is strongly influenced by temperature, pH, and calcium concentration.
This improves understanding of natural food chemistry and stability behavior.
In wine stabilization science, calcium tartrate is particularly relevant because it can slowly precipitate over time, especially at low temperatures, and this can create visible crystals in bottled wine even though the product is not spoiled, which is why winemakers use stabilization techniques to control its formation before bottling.
This is part of quality assurance in beverage production.
This improves product clarity and consumer acceptance.
In cold storage behavior of beverages, calcium tartrate is important because refrigeration can increase crystal formation, and this is why some drinks may develop harmless sediment after being stored at low temperatures for long periods.
This is a physical–chemical rather than microbial change.
This improves understanding of storage-induced changes.
In food processing of grape and fruit concentrates, calcium tartrate formation can affect filtration and clarification steps, because its low solubility can lead to deposits that must be removed to ensure smooth texture and clear appearance in final products.
This makes filtration and stabilization steps more important in production.
This improves processing efficiency and product clarity.
E354 Calcium tartrate is used as a model compound to study how organic acids interact with metal ions to form crystals, helping scientists understand nucleation, growth rate, and solubility behavior in aqueous systems.
Its predictable crystallization makes it useful for research.
E354 Calcium tartrate improves material science and crystallization modeling.
Melting point: decomposes [CRC10]
alpha: [α]D20 +5.0～+8.0゜ (c=5, dil. HCl)
Density: 1.878 [at 20℃]
vapor pressure: 0 Pa at 25℃
solubility: soluble in dilute acid solutions; slightly soluble in ethanol
form: powder
color: white
Water Solubility: g/100g H2O: 0.026 (0°C), 0.034 (20°C), 0.130 (80°C) [LAN05]; soluble dilute HCl, HNO3 [MER06]
Merck: 13,1714
Cosmetics Ingredients Functions: SKIN CONDITIONING
LogP: -3.6 at 20℃
E354 Calcium tartrate is an organic calcium salt and a tartrate salt.
E354 Calcium tartrate is strongly associated with winemaking and grape-derived systems, where it naturally forms as a crystalline precipitate during wine aging when tartaric acid reacts with calcium present in grapes or winery equipment, and this behavior is actually used as part of stabilization techniques to prevent unwanted crystal formation in bottled wine.
E354 Calcium tartrates controlled precipitation is important for clarity and visual quality.
This improves beverage stability and product appearance.
In food processing systems, calcium tartrate can help stabilize acidity in products derived from fruit processing, especially grape-based or tartaric-acid-rich systems, where controlling mineral balance is important to prevent instability or unwanted crystallization.
It helps maintain consistent texture and appearance.
E354 Calcium tartrate improves product uniformity and quality control.
E354 Calcium tartrate plays a role in preventing or controlling tartaric acid-related crystallization issues that can cause sediment or haze in bottled drinks, particularly wines and fruit-based beverages that undergo long storage or cooling.
This is important for maintaining consumer acceptance.
E354 Calcium tartrate improves clarity and storage stability.
E354 Calcium tartrate is sometimes relevant in controlled mineral systems because calcium interactions with organic acids are important in understanding absorption, stability, and formulation behavior of calcium-containing compounds.
It is not a primary active ingredient but a related mineral system component.
E354 Calcium tartrate improves formulation understanding and mineral chemistry control.
E354 Calcium tartrate is used in processes where controlled precipitation of calcium salts is needed, particularly in systems that require removal or stabilization of calcium ions in aqueous solutions.
Its low solubility makes it useful for separation processes.
E354 Calcium tartrate improves ion control and process efficiency.
E354 Calcium tartrate can indirectly contribute to firmness or stabilization in certain fruit-based gels or processed fruit products by influencing calcium availability and acid–base balance in the system.
This helps maintain structural integrity of some formulations.
E354 Calcium tartrate improves texture stability and product consistency.
In analytical chemistry and laboratory studies, E354 Calcium tartrate is sometimes used as a reference compound in studying tartaric acid behavior, crystallization kinetics, and calcium–organic acid interactions in aqueous environments.
This helps researchers model real food and beverage systems.
E354 Calcium tartrate improves scientific understanding of crystallization and mineral interactions.
E354 Calcium tartrates are considered relatively biodegradable, and calcium tartrate itself is environmentally stable but not highly persistent, making it part of naturally cycling organic acid–mineral systems in soil and water environments.
This links it to natural biogeochemical cycles.
This improves environmental compatibility understanding.
In material science and crystallization research, E354 Calcium tartrate is studied for its crystal formation behavior, including how temperature, pH, and ion concentration affect its precipitation, which is useful in understanding broader mineral crystallization processes.
This is relevant in both food and industrial systems.
E354 Calcium tartrate improves crystallization control and material insight.
E354 Calcium tartrate is important because managing calcium tartrate formation helps prevent unexpected crystal deposits in bottled wine, which can be mistaken for spoilage by consumers even though it is harmless.
Proper stabilization techniques reduce this risk.
E354 Calcium tartrate improves product perception and quality assurance.
E354 Calcium tartrate is relevant because it demonstrates how calcium ions can be “locked” into insoluble organic complexes, which is important in both food systems and biological environments where calcium availability affects texture, stability, and reactivity.
This principle is widely applied in food formulation science.
E354 Calcium tartrate improves mineral interaction understanding and formulation control.
E354 Calcium tartrate can be used to study ion pairing and precipitation thresholds, especially in systems where researchers need to model how calcium behaves in the presence of organic acids like tartaric acid.
It helps define solubility limits and equilibrium conditions.
E354 Calcium tartrate improves experimental accuracy and chemical modeling.
E354 Calcium tartrate is part of natural organic matter cycling, especially in plant-rich environments where organic acids interact with soil minerals, contributing to slow mineral transformation processes in ecosystems.
It is not persistent and is part of natural biochemical turnover.
E354 Calcium tartrate improves environmental chemistry understanding.
E354 Calcium tartrate can serve as an example of scale-like precipitation behavior, helping engineers understand how organic acid salts may form deposits under certain pH and mineral conditions in pipes or processing equipment.
This helps design better anti-scaling strategies.
E354 Calcium tartrate improves industrial process control and maintenance planning.
E354 Calcium tartrate is important because its crystal formation can be mistaken by consumers for contamination, so understanding its behavior helps producers design clearer labeling and better stabilization techniques to avoid confusion.
This is a key part of consumer-facing quality control.
E354 Calcium tartrate improves product perception and market acceptance.
Uses:
E354 Calcium tartrate is mainly used as a stabilizer, acidity-related mineral control agent, and crystallization regulator because it helps manage tartaric acid systems and calcium interactions in food and beverage processing.
In wine and beverage production, it is used to control and prevent unwanted crystal formation and improve clarity.
E354 Calcium tartrate improves visual quality and storage stability.
In fruit-based food systems, E354 Calcium tartrate is used to stabilize acidity and mineral balance.
This improves texture and product consistency.
In food processing, it is used to support stabilization of acid–calcium systems.
E354 Calcium tartrate improves product quality control.
In industrial chemical systems, it is used for controlled calcium ion precipitation and stabilization.
This improves process control and separation efficiency.
In analytical and research applications, E354 Calcium tartrate is used to study crystallization and mineral interactions.
This improves scientific understanding of calcium–acid systems.
E354 Calcium tartrate is mainly used as a stabilizing and crystallization-related compound because it helps control tartaric acid–calcium interactions in food, beverage, and research systems.
In wine and beverage production, E354 Calcium tartrate is involved in controlling crystal formation and improving clarity.
This improves visual quality and stability.
In fruit-based food processing, it is used to understand and manage mineral–acid stability.
E354 Calcium tartrate improves texture and consistency control.
In industrial crystallization research, it is used as a model compound for studying precipitation.
This improves scientific understanding of crystal formation.
E354 Calcium tartrate is used to study calcium–organic acid interactions.
This improves chemical modeling accuracy.
In food quality control systems, it is used as a reference for preventing unwanted sediment formation.
E354 Calcium tartrate improves product consistency and consumer perception.
E354 Calcium tartrate is mainly used as a crystallization-related stabilizing compound and reference material, because it forms from natural tartaric acid and calcium interactions and helps explain, control, or manage crystal formation processes in food, beverage, and research systems.
E354 Calcium tartrate is involved in controlling tartrate crystal formation, which helps improve product clarity and prevents the appearance of visible crystals in bottled wine during storage or cooling.
E354 Calcium tartrate improves visual quality and consumer acceptance.
In fruit juice and grape-based products, it is used as part of stability control strategies to manage mineral–acid interactions that can otherwise lead to sediment or haze formation over time.
E354 Calcium tartrate improves appearance and storage stability.
In food processing systems, it is used to understand and control calcium–tartaric acid reactions, especially in products containing natural fruit acids where crystallization may occur during processing or storage.
E354 Calcium tartrate improves consistency and quality control.
In industrial crystallization and process engineering, it is used as a model compound to study precipitation behavior, solubility limits, and crystal growth mechanisms in aqueous systems.
E354 Calcium tartrate improves process optimization and material understanding.
E354 Calcium tartrate is used as a reference substance for studying calcium–organic acid interactions and equilibrium behavior in solution systems.
E354 Calcium tartrate improves experimental accuracy and chemical modeling.
In food quality control and product development, it is used indirectly as a reference for designing stabilization methods that prevent unwanted crystal formation in finished beverages and processed fruit products.
E354 Calcium tartrate improves product reliability and consumer perception.
Safety Profile:
E354 Calcium tartrate is generally considered a low hazard compound, especially because it is a naturally occurring salt formed in food systems like wine, but it can still cause mild irritation in concentrated handling situations.
The main hazard is mild irritation of skin, eyes, and respiratory system, especially from dust exposure during industrial processing.
Protective equipment and ventilation are recommended.
E354 Calcium tartrate improves workplace safety.
Skin contact is usually low risk, though prolonged exposure to dust may cause mild irritation or dryness.
Washing with water is sufficient.
Eye contact may cause moderate irritation, especially from powder exposure.
Protective eyewear is recommended.
Inhalation of dust may cause temporary respiratory irritation, particularly in poorly ventilated environments.
Dust control measures are recommended.
E354 Calcium tartrate is not flammable and is chemically stable under normal storage conditions.
This improves handling safety.
From a toxicological perspective, calcium tartrate is considered low risk due to its occurrence in natural food systems and low solubility, which limits absorption.
However, industrial exposure should still be controlled.
This requires standard hygiene practices.
E354 Calcium tartrate is considered low risk and naturally compatible with biological systems, since tartrate compounds are part of natural plant and fermentation chemistry.
This improves environmental safety and biodegradability understanding.
