Polyoxyethylene (20) Sorbitan Monooleate, commonly known as Tween 80 or Polysorbate 80, is a nonionic surfactant and emulsifier widely used in food, pharmaceuticals, cosmetics, and industrial formulations.
E433 Polyoxyethylene (20) sorbitan monooleate appears as a viscous, amber-colored liquid with a mild characteristic odor and excellent solubilizing properties.
E433 Polyoxyethylene (20) sorbitan monooleate is recognized as a safe food additive, functioning as an emulsifier, stabilizer, and dispersing agent in a wide variety of processed foods.
E433 Polyoxyethylene (20) sorbitan monooleate is also employed in drug formulations, vaccines, creams, and personal care products for its emulsifying and wetting properties.
CAS Number: 9005-65-6
EC Number: 500-019-9
Molecular Formula: C64H124O26 (approximate composition)
Molecular Weight: ~1310 g/mol (mixture-dependent)
Synonyms: Polysorbate 80, Tween 80, Polyoxyethylene (20) Sorbitan Monooleate, Sorbitan Monooleate Ethoxylated, PEG-20 Sorbitan Monooleate, E433 Emulsifier, Food Emulsifier Tween 80, Pharmaceutical Solubilizer Tween 80, E433 Polyoxyethylene (20) sorbitan monooleate, Polysorbate 80, Tween 80, Polyoxyethylene sorbitan monooleate, PEG-20 sorbitan monooleate, Polyoxyethylene (20) sorbitan oleate, Ethoxylated sorbitan monooleate, Polyoxyethylene sorbitan oleate, Sorbitan monooleate ethoxylate, Sorbitan monooleate polyoxyethylene ether, Polysorbate-80, Polyoxyethylene sorbitan monooleate emulsifier, Polysorbate 80 food grade, Polysorbate 80 pharmaceutical grade, Polysorbate 80 cosmetic grade, Polysorbate 80 technical grade, Polysorbate 80 industrial grade, Polysorbate 80 laboratory grade, Polysorbate 80 research grade, Polysorbate 80 pure, Polysorbate 80 high purity, Polysorbate 80 refined, Polysorbate 80 stabilized, Polysorbate 80 certified, Polysorbate 80 certified standard, Polysorbate 80 analytical standard, Polysorbate 80 laboratory standard, Polysorbate 80 reagent, Polysorbate 80 test reagent, Polysorbate 80 bulk chemical, Polysorbate 80 commercial grade, Polysorbate 80 raw material, Polysorbate 80 fine chemical, Polysorbate 80 specialty chemical, Polysorbate 80 active ingredient, Polysorbate 80 functional ingredient, Polysorbate 80 specialty ingredient, Polysorbate 80 functional additive, Polysorbate 80 specialty additive, Polysorbate 80 emulsifier, Polysorbate 80 solubilizer, Polysorbate 80 stabilizer, Polysorbate 80 dispersant, Polysorbate 80 wetting agent, Polysorbate 80 surfactant, Polysorbate 80 solubilizing agent, Polysorbate 80 solubilizer for vitamins, Polysorbate 80 solubilizer for flavors, Polysorbate 80 solubilizer for oils, Polysorbate 80 emulsifier for foods, Polysorbate 80 emulsifier for pharmaceuticals, Polysorbate 80 emulsifier for cosmetics, Polysorbate 80 emulsifier for vaccines
APPLICATIONS
Polyoxyethylene (20) Sorbitan Monooleate (E433) is used in the food industry.
E433 Polyoxyethylene (20) sorbitan monooleate acts as an emulsifier in ice cream, margarine, and sauces.
E433 Polyoxyethylene (20) sorbitan monooleate improves texture, creaminess, and stability in processed foods.
E433 Polyoxyethylene (20) sorbitan monooleate is incorporated in bakery products.
E433 Polyoxyethylene (20) sorbitan monooleate enhances dough handling and shelf life.
E433 stabilizes fat and water systems in baked goods.
E433 Polyoxyethylene (20) sorbitan monooleate is used in beverages and syrups.
E433 Polyoxyethylene (20) sorbitan monooleate solubilizes essential oils and flavoring agents.
E433 prevents separation and improves clarity in drinks.
E433 Polyoxyethylene (20) sorbitan monooleate is applied in pharmaceuticals.
E433 acts as a solubilizer for poorly soluble drugs.
E433 Polyoxyethylene (20) sorbitan monooleate is used in vaccines, injections, and suspensions.
E433 Polyoxyethylene (20) sorbitan monooleate is included in topical creams and ointments.
E433 stabilizes emulsions and enhances spreadability.
E433 Polyoxyethylene (20) sorbitan monooleate increases penetration of active ingredients.
E433 Polyoxyethylene (20) sorbitan monooleate is used in cosmetics and personal care.
E433 Polyoxyethylene (20) sorbitan monooleate acts as an emulsifier in lotions, creams, and shampoos.
E433 Polyoxyethylene (20) sorbitan monooleate improves sensory feel and consistency of formulations.
E433 Polyoxyethylene (20) sorbitan monooleate is employed in biotechnology and microbiology.
E433 prevents cell aggregation in culture media.
E433 Polyoxyethylene (20) sorbitan monooleate is used as a stabilizer in protein and enzyme formulations.
E433 Polyoxyethylene (20) sorbitan monooleate is incorporated in industrial cleaners and lubricants.
E433 Polyoxyethylene (20) sorbitan monooleate acts as a dispersant and wetting agent.
E433 Polyoxyethylene (20) sorbitan monooleate improves formulation homogeneity.
E433 Polyoxyethylene (20) sorbitan monooleate is used in the food industry.
E433 Polyoxyethylene (20) sorbitan monooleate acts as an emulsifier in processed foods.
E433 Polyoxyethylene (20) sorbitan monooleate stabilizes oil-in-water emulsions.
E433 Polyoxyethylene (20) sorbitan monooleate is applied in bakery products.
E433 Polyoxyethylene (20) sorbitan monooleate improves texture of cakes.
E433 Polyoxyethylene (20) sorbitan monooleate extends shelf life of baked goods.
E433 Polyoxyethylene (20) sorbitan monooleate is used in ice cream.
E433 Polyoxyethylene (20) sorbitan monooleate prevents ice crystal growth.
E433 Polyoxyethylene (20) sorbitan monooleate ensures smooth mouthfeel.
E433 Polyoxyethylene (20) sorbitan monooleate is incorporated in margarine.
E433 Polyoxyethylene (20) sorbitan monooleate stabilizes fat-water emulsions.
E433 Polyoxyethylene (20) sorbitan monooleate improves spreadability.
E433 Polyoxyethylene (20) sorbitan monooleate is used in chocolate production.
E433 Polyoxyethylene (20) sorbitan monooleate improves viscosity control.
E433 Polyoxyethylene (20) sorbitan monooleate enhances gloss and flow.
E433 Polyoxyethylene (20) sorbitan monooleate is applied in salad dressings.
E433 Polyoxyethylene (20) sorbitan monooleate prevents separation of oil and vinegar.
E433 Polyoxyethylene (20) sorbitan monooleate ensures stable emulsions.
E433 Polyoxyethylene (20) sorbitan monooleate is used in dairy products.
E433 Polyoxyethylene (20) sorbitan monooleate improves dispersion of fats.
E433 Polyoxyethylene (20) sorbitan monooleate enhances creaminess in flavored milk.
E433 Polyoxyethylene (20) sorbitan monooleate is incorporated in beverages.
E433 Polyoxyethylene (20) sorbitan monooleate solubilizes essential oils in soft drinks.
E433 Polyoxyethylene (20) sorbitan monooleate ensures clarity in flavored waters.
E433 Polyoxyethylene (20) sorbitan monooleate is used in pharmaceuticals.
E433 Polyoxyethylene (20) sorbitan monooleate serves as an excipient.
E433 Polyoxyethylene (20) sorbitan monooleate improves solubility of active ingredients.
E433 Polyoxyethylene (20) sorbitan monooleate is applied in cosmetics.
E433 Polyoxyethylene (20) sorbitan monooleate acts as an emulsifier in creams and lotions.
E433 Polyoxyethylene (20) sorbitan monooleate improves stability of skincare formulations.
E433 Polyoxyethylene (20) sorbitan monooleate is used in veterinary formulations.
E433 Polyoxyethylene (20) sorbitan monooleate enhances solubility of lipophilic drugs.
E433 Polyoxyethylene (20) sorbitan monooleate supports stable dosage forms.
DESCRIPTION
E433 Polyoxyethylene (20) sorbitan monooleate is a non-ionic surfactant.
E433 Polyoxyethylene (20) sorbitan monooleate is commonly known as Polysorbate 80.
E433 Polyoxyethylene (20) sorbitan monooleate is widely used in food, pharmaceutical, and cosmetic industries.
E433 Polyoxyethylene (20) sorbitan monooleate has the CAS number 9005-65-6.
E433 Polyoxyethylene (20) sorbitan monooleate has the E number E433.
E433 Polyoxyethylene (20) sorbitan monooleate is approved as a food additive worldwide.
E433 Polyoxyethylene (20) sorbitan monooleate appears as a viscous yellow to amber liquid.
E433 Polyoxyethylene (20) sorbitan monooleate has a slight characteristic odor.
E433 Polyoxyethylene (20) sorbitan monooleate is soluble in water and ethanol.
E433 Polyoxyethylene (20) sorbitan monooleate is used to stabilize emulsions and dispersions.
E433 Polyoxyethylene (20) sorbitan monooleate has excellent solubilizing properties.
E433 Polyoxyethylene (20) sorbitan monooleate is biodegradable under environmental conditions.
E433 Polyoxyethylene (20) sorbitan monooleate is considered safe within regulated limits.
E433 Polyoxyethylene (20) sorbitan monooleate should be stored in closed containers away from heat.
E433 Polyoxyethylene (20) sorbitan monooleate is compliant with international food and cosmetic regulations.
E433 Polyoxyethylene (20) Sorbitan Monooleate is an amber to yellow viscous liquid.
E433 Polyoxyethylene (20) sorbitan monooleate is soluble in water, ethanol, and other polar solvents.
E433 Polyoxyethylene (20) sorbitan monooleate has high hydrophilic-lipophilic balance (HLB ~15), making it an excellent emulsifier for oil-in-water systems.
E433 is derived from sorbitan monooleate reacted with ethylene oxide.
E433 Polyoxyethylene (20) sorbitan monooleate is biodegradable and considered safe in regulated concentrations.
E433 Polyoxyethylene (20) sorbitan monooleate has a long history of use in food, pharmaceuticals, and cosmetics.
E433 improves product stability, prevents phase separation, and enhances texture.
E433 Polyoxyethylene (20) sorbitan monooleate is nonionic and compatible with a wide range of surfactants.
It is widely recognized as an essential emulsifier in both consumer and industrial formulations.
PROPERTIES
Appearance: Amber to yellow viscous liquid
Odor: Mild characteristic odor
Density: ~1.06 g/cm³ (20°C)
Viscosity: ~400 mPa·s (25°C)
Melting Point: ~−5°C
Boiling Point: >100°C (decomposes)
Flash Point: ~>150°C
Solubility: Soluble in water, ethanol, methanol; dispersible in oils
HLB Value: ~15 (strongly hydrophilic)
Stability: Stable under normal conditions; sensitive to extreme heat and strong oxidizers
Storage Temperature: Store at 15–30°C in tightly sealed containers
FIRST AID
Inhalation:
Remove to fresh air if mist or vapors are inhaled.
Seek medical attention if symptoms develop.
Skin Contact:
Wash with soap and water.
Generally considered non-irritant.
Seek medical help if irritation occurs.
Eye Contact:
Flush with plenty of water for at least 15 minutes.
Seek medical advice if irritation persists.
Ingestion:
Rinse mouth with water.
Non-toxic in small amounts; seek medical attention if large amounts ingested.
Note to Physicians:
Treat symptomatically.
No specific antidote required.
HANDLING AND STORAGE
Handling:
Avoid unnecessary contact with skin and eyes during bulk use.
Wear standard protective clothing and gloves in industrial handling.
Ventilation:
Ensure adequate ventilation in processing areas.
Avoidance:
Avoid strong oxidizing agents and excessive heat.
Do not mix with incompatible chemicals without testing.
Spill and Leak Procedures:
Absorb with inert material (sand, vermiculite).
Clean spills with water and detergent.
Dispose in accordance with local regulations.
Storage:
Store in sealed containers in a cool, dry, well-ventilated area.
Protect from light, heat, and moisture.