PRODUCTS

E460 CELLULOSE

E460 Cellulose is commonly used in powdered and granulated products to prevent clumping and ensure free-flowing properties.
E460 Cellulose acts as a thickener in sauces, soups, and other liquid products, providing the desired viscosity without altering flavor.
As a natural, plant-derived ingredient, E460 Cellulose is suitable for vegetarian and vegan products.

CAS Number: 9004-34-6
EC Number: 232-674-9
MDL number: MFCD00081512
Molecular Formula: (C6H10O5)n, “n” represents the number of repeating glucose units.
Molecular Weight: Varies depending on the degree of polymerization, typically ~36,000 to 100,000 g/mol (average range)

SYNONYMS:
Cotton linters, Cellulose crystalline, Cellulose regenerated, Cellulose, powder, Cellulose, powdered, Hydroxycellulose, Powdered cellulose, Pyrocellulose, Rayon, MCC, Avicel, Solka-Floc, α-Cellulose, Cellulose powder, Arbocel, Microcrystalline Cellulose, Cellulose, Microcrystalline, Cellulose Regenerated, OP1R32D61U, Avicel PH, CCRIS 6600, CELLULOSE MICROCRYSTALLINE, CELLULOSE, MICROCRYSTALLINE (EP MONOGRAPH), CELLULOSE, MICROCRYSTALLINE (II), CELLULOSE, MICROPOROUS, CELLULOSE,MICROCRYSTALLINE, CELLULOSUM MICROCRYSTALLINUM, CP-305, Cellulose Powders, Celphere CP-305, Cephere, DISPERSIBLE CELLULOSE, EINECS 232-674-9, Ethispheres250, MICROCRYSTALLINE CELLULOSE (E460), MICROCRYSTALLINE CELLULOSE (MART.), MICROCRYSTALLINE CELLULOSE (USP-RS), MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 101, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 102, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 102 SCG, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 103, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 105, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 112, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 200, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 200 LM, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 301, MICROCRYSTALLINE CELLULOSE IN FDA INACTIVE INGREDIENTS INCLUDES MICROCRYSTALLINE CELLULOSE 302, NSC 225105, PHARMACEL, Rayon flock, Sentry aq mardel clout, UNII-5XDI2TS1EZ, UNII-7T9FYH5QMK, UNII-91B875MM4H, UNII-C8DF2GF8L2, UNII-HHJ82DN6MJ, UNII-KO5GYV0DCB, UNII-L5EC3P45R8, UNII-OP1R32D61U, UNII-PNR0YF693Y, UNII-SMD1X3XO9M, UNII-VG6UJI79NF, UNII-W7YXH6D4BD, UNII-X7XJ6RM9Q2, Wood pulp, bleached, Cellulose, Microcrystalline Cellulose, Powdered Cellulose, Purified Cellulose, Plant Cellulose, Wood Cellulose, Cotton Cellulose, Alpha-Cellulose, Fibrous Cellulose, Cellulose Fiber, β-Cellulose, Microcrystalline Powdered Cellulose, MCC, Avicel, Alphacel, Solka-Floc, Arbocel, Vitacel, E460, Cellulose Gum Base, Natural Cellulose Polymer, MCC, Microcrystalline Cellulose, E460 / INS 460, Microcrystalline Plant Fiber (for technical use),

E460 Cellulose is a plant-based polysaccharide used extensively in the food industry.
E460 Cellulose serves various functions, including as a food additive, stabilizer, thickener, and anti-caking agent.
E460 Cellulose is a naturally occurring polymer consisting of glucose units linked by 1-4 beta glycosidic bonds.

E460 Cellulose is a valuable additive across industries such as pharmaceuticals, food, cosmetics, and others.
E460 Cellulose's suitability for different applications is determined by various properties including particle size, density, compressibility index, angle of repose, powder porosity, hydration swelling capacity, moisture sorption capacity, moisture content, crystallinity index, crystallite size, as well as mechanical properties like hardness and tensile strength.

E460 Cellulose is a white powder derived from the Cellulose manufacturing process using high-quality wood pulp.
Registered under CAS number 9004-34-6, it exhibits rapid disintegration in water.
Widely employed in medicine and food, E460 Cellulose functions as an emulsifier, stabilizer, and binding agent in tablet formulations.

E460 Cellulose is obtained from wood, sunflower stalks, or cotton waste (not from recycled paper!).
E460 Cellulose is a filler and water binder, and the main component of paper tissues.
As microcrystalline E460 Cellulose, it increases the melting stability of ice cream or serves as a fat substitute.

E460 Cellulose is also used as a filler in pastes and sauces, an anti-caking agent for grated cheese, and an opaque agent for confectionery.
E460 Cellulose is produced from wood, cotton, or other Cellulose-containing plants.
After lignin removal, E460 Cellulose is treated with caustic soda and then undergoes crystallization processing.

The distinctive feature of additive E460(i) is the precisely controlled size of its crystalline particles, which gives the substance high stability and unique properties.
Additive E460(i) is insoluble in water but forms stable colloidal suspensions.
Stabilizer E460(i) is widely used in the production of yoghurts, desserts, and creams to stabilize texture and ensure product quality.

E460 Cellulose, the main component is a linear polysaccharide substance bound by β-1,4-glucoside bonds, which is natural E460 Cellulose hydrolyzed by dilute acid to the limit degree of polymerization ( LOOP) free-flowing very fine short rod-like or powder-like porous particles, composed of white, odorless, tasteless crystalline powder.
In general plant fibers, E460 Cellulose accounts for about 70%, and the other 30% is amorphous.

Different particle size and water content of E460 Cellulose have different characteristics and application ranges.
It is a purified, partially depolymerised E460 Cellulose powder derived from plant fibres.
E460 Cellulose is widely used in pharmaceutical, food, and cosmetic applications for its compressibility, binding, and bulking properties.

E460 Cellulose is a naturally occurring polysaccharide and one of the most abundant organic polymers on Earth.
E460 Cellulose is the primary structural component of plant cell walls and is obtained mainly from wood pulp, cotton fibers, and other plant materials.
E460 Cellulose is composed of linear chains of β(1→4) linked D-glucose units that form highly ordered fibrous structures through extensive hydrogen bonding.

Because of this strong intermolecular bonding, E460 Cellulose possesses high mechanical strength, chemical stability, and resistance to many solvents.
E460 Cellulose is insoluble in water and most organic solvents but can absorb water and swell.
E460 Cellulose is biodegradable, renewable, non-toxic, odorless, tasteless, and environmentally friendly.

Approved within the European Union as a thickener, stabilizer or emulsifier, microcrystalline E460 Cellulose was granted the E number E460(i) with basic E460 Cellulose given the number E460.
Different properties of E460 Cellulose are measured to qualify its suitability to such utilization, namely particle size, density, compressibility index, angle of repose, powder porosity, hydration swelling capacity, moisture sorption capacity, moisture content, crystallinity index, crystallite size, and mechanical properties such as hardness and tensile strength.

E460 Cellulose is highly versatile because its structure can be chemically modified to produce many derivatives such as carboxymethyl E460 Cellulose, hydroxypropyl methylE460 Cellulose, methylE460 Cellulose, and E460 Cellulose acetate, each possessing specialized industrial functions.
E460 Cellulose is used to reduce the use of fat in foods, to control the growth of ice crystals, to suspend solid particles, to provide creamy texture and opacity, and to help release texture and flavor.

E460 Cellulose is mostly used in reduced-fat ice cream, frozen desserts, bakery, chocolate drinks, confectionery, salad dressings and fillings.
E460 Cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production.
The most common form of E460 Cellulose is used in vitamin supplements or tablets.

E460 Cellulose is a natural substance that forms the primary structural component of plant cell walls.
E460 Cellulose belongs to the group of polysaccharides and consists of glucopyranose units linked by β-1,4-glycosidic bonds.
E460 Cellulose is the most abundant organic compound on Earth.
Natural E460 Cellulose is derived from wood, cotton, flax, and other plants.

There are two forms of food additive E460:
E460(i) — Microcrystalline E460 Cellulose (E460 Cellulose gel)
E460(ii) — Powdered E460 Cellulose.
They differ in particle size but share similar properties and the same origin.

E460 Cellulose is a multi-functional ingredient commonly used as an anticaking agent, binder, thickener or stabilizer.
The European food additive number for E460 Cellulose is E460(i).
E460 Cellulose is a purified, partially depolymerised it prepared by treating alpha-E460 Cellulose, obtained as a pulp from strains of fibrous plant material, with mineral acids.

The degree of polymerisation (DP) is typically less than 400.
E460 Cellulose is a natural constituent of all plant fibers.
E460 Cellulose is insoluble and indigestible, having a detoxifying role for the digestive tract.

E460 Cellulose is a plant-based food additive derived from cellulose, used as a bulking agent, anti-caking agent, and stabilizer in food products.
E460 Cellulose is considered safe and approved by the EFSA.
Things worth knowing about "E460 Cellulose"

In the food industry, E460 Cellulose is used as an additive and is divided into two subtypes:
E460 Cellulose i – Microcrystalline E460 Cellulose (E460 Cellulose): A purified and compacted form of cellulose produced by acid hydrolysis.
E460 Cellulose ii – Powdered E460 Cellulose: A mechanically milled, fibrous form of cellulose.

E460 Cellulose is a linear polymer composed of repeating beta-D-glucopyranosyl units linked via (1,4) glycosidic bonds.
E460 Cellulose is a naturally non-caloric indigestible dietary fiber that is widely used in food, cosmetics and pharmaceutical industries.
E460 Cellulose's primary purpose is as an anticaking agent in food and pharmaceutical processing.

E460 Cellulose is a food additive classified as halal.
E460 Cellulose refers to a group of food additives consisting of E460 Cellulose(i) Microcrystalline E460 Cellulose and E460 Cellulose(ii) Powdered E460 Cellulose.
These substances are obtained from purified plant cellulose and serve multiple functions in the food industry as thickeners, stabilizers, anti-caking agents, binders, and texture modifiers.

E460 Cellulose refers to a group of food additives consisting of E460 Cellulose(i) Microcrystalline E460 Cellulose and E460 Cellulose(ii) Powdered E460 Cellulose.
These substances are derived from purified plant cellulose and serve multiple functions in the food industry as thickeners, stabilizers, anti-caking agents, binders, and texture modifiers.

E460 Cellulose is commonly found in baked goods, dairy products, sauces, soups, spreads, ice cream, nutritional supplements, and pharmaceutical tablets, cellulose improves texture and prevents clumping.
E460 Cellulose is recognized as safe for consumption by major food safety authorities, including the FDA, EFSA, and JECFA.
E460 Cellulose provides a homogeneous texture even at low doses, improves free flow, and limits clumping caused by moisture.

USES and APPLICATIONS of E460 CELLULOSE:
Food Additive: E460 Cellulose is used to enhance the texture and stability of various food products, ensuring consistency and quality.
Dietary Fiber: As a source of insoluble fiber, E460 Cellulose adds bulk to food, aiding in digestion and promoting a healthy digestive system.
Stabilizer: E460 Cellulose helps stabilize emulsions and prevent ingredients from separating, maintaining the desired consistency of food products.

Anti-Caking Agent: E460 Cellulose is commonly used in powdered and granulated products to prevent clumping and ensure free-flowing properties.
Thickening Agent: E460 Cellulose acts as a thickener in sauces, soups, and other liquid products, providing the desired viscosity without altering flavor.
Plant-Based: As a natural, plant-derived ingredient, E460 Cellulose is suitable for vegetarian and vegan products.

Texturizer: E460 Cellulose improves the mouthfeel and texture of various food products, making them more appealing to consumers.
In cosmetics, E460 Cellulose serves multiple purposes including abrasiveness, absorption, anti-caking, viscosity enhancement in aqueous solutions, bulking, stabilization of emulsions, adjustment of slip, and texturizing.

These functionalities make E460 Cellulose a common ingredient in various hair care, skin care, and makeup products.
Pharmaceutical Formulations: E460 Cellulose is used as a binder, filler, and disintegrant in tablets and capsules due to its excellent compressibility and flow characteristics.
Food and Beverage Products: E460 Cellulose serves as a fat replacer, stabiliser, and texturiser in low-fat and processed foods (E460).

Cosmetic and Personal Care: E460 Cellulose acts as a bulking agent and consistency enhancer in creams, powders, and personal care formulations.
Laboratory and Industrial Applications: E460 Cellulose is used in formulation development and quality control processes where excipient-grade E460 Cellulose is required.
Uses of E460 Cellulose: Anti-caking agents, emulsifiers, binders, disintegrating agents, dispersants, organization modifiers, non-nutrient leavening agents, emulsion stabilizers, thermal stabilizers, carriers for fast drying, finely dispersing agents and tableting agents.

E460 Cellulose E460 Cellulose is widely used in pharmaceutical, cosmetics, food and other industries.
E460 Cellulose has extremely broad industrial applications because of its physical strength, stability, biodegradability, and functional versatility.
In the food industry, E460 Cellulose is commonly used as a bulking agent, anti-caking agent, stabilizer, emulsifier, thickener, fat replacer, and texture enhancer.

E460 Cellulose improves consistency and mouthfeel in processed foods while contributing little or no calories.
In bakery products, E460 Cellulose improves texture, increases fiber content, and enhances moisture retention.
E460 Cellulose is widely used in breads, cakes, pastries, cookies, and gluten-free products to improve structure and shelf life.

In low-fat and reduced-calorie foods, E460 Cellulose acts as a fat substitute by providing creamy texture and volume.
In dairy and frozen dessert products such as ice cream, E460 Cellulose helps stabilize emulsions and prevents ice crystal formation.
E460 Cellulose is also used in sauces, dressings, soups, instant noodles, processed meats, and beverage products to improve stability and consistency.

In pharmaceuticals, microcrystalline E460 Cellulose is one of the most important tablet excipients used worldwide.
E460 Cellulose functions as a binder, filler, disintegrant, and compression aid in tablet manufacturing.
Its excellent compressibility and flowability make E460 Cellulose ideal for direct compression processes.

E460 Cellulose is also used in capsules, powders, suspensions, controlled-release formulations, and dietary supplements.
In cosmetics and personal care products, E460 Cellulose derivatives are used in creams, lotions, shampoos, toothpaste, makeup products, and gels as stabilizers, thickeners, absorbents, and texture modifiers.

The paper industry is one of the largest consumers of E460 Cellulose.
E460 Cellulose provides structural strength, durability, and printability in paper and cardboard products.
In textiles, E460 Cellulose from cotton and regenerated fibers is essential for producing fabrics, rayon, viscose, and industrial fibers.

E460 Cellulose is also widely used in filtration materials, construction products, biodegradable plastics, paints, adhesives, ceramics, batteries, medical dressings, food packaging, and agricultural formulations.
Due to increasing environmental concerns, E460 Cellulose-based biodegradable materials are becoming increasingly important as alternatives to petroleum-derived plastics.

E460 Cellulose has use in cosmetics as an abrasive, absorbent, anti-caking agent, aqueous viscosity increasing agent, binder, bulking agent, emulsion stabilizer, slip modifier, and texturizer, which can be found in various hair and skin care products as well as makeup.
The E460 Cellulose is a valuable additive in pharmaceutical, food, cosmetic and other industries.

Due to these characteristics, E460 Cellulose has major applications in food, pharmaceuticals, cosmetics, paper, textiles, construction materials, filtration systems, paints, plastics, and many industrial products.
In the food industry, E460 Cellulose used as a food additive, including powdered E460 Cellulose and microcrystalline E460 Cellulose.

E460 Cellulose is widely used because of its excellent bulking, stabilizing, anti-caking, thickening, emulsifying, and texturizing properties.
E460 Cellulose is also used in plaque assays for counting viruses, as an alternative to carboxymethyl Cellulose.
E460 Cellulose is used food additive with thickening, filling, anti-caking and emulsifying role.

For industrial use E460 Cellulose is obtained from wood, cotton etc.
E460 Cellulose comes in the form of E 460(i) – microcrystalline E460 Cellulose or E 460(ii) – powdered E460 Cellulose.
E460 Cellulose is used as a substance-support for other food additives.

E460 Cellulose is used in the quantities on the recipes in dairy products, in sweets, creams, emulsified fat spreads with or without flavors, sauces, snacks, ice creams, processed, preserved fruits and vegetables, meat products, fish, eggs, spices, soups, broths, edible membranes, vegetable protein products, nutritional supplements, mustard, alcoholic and non-alcoholic beverages, dietetic products etc.

In the food industry, wood-derived E460 Cellulose is typically used, obtained by purifying wood pulp from lignin and other impurities through chemical or mechanical treatment.
Food: Food-grade E460 Cellulose is commonly used in combination with CMC, or methylE460 Cellulose.
Also, E460 Cellulose is together with starch to improve thickening.

-Suggested Uses of E460 Cellulose:
Spice & Powder Blends: Free flow and clump control.
Baked Goods & Gluten-Free: Crumb structure, volume, and moisture management.
Confectionery & Gum: Powder coating and texture enhancement.
Dairy Desserts & Ice Cream: Fat substitution, mouthfeel, and melting behavior control.
Beverage Powders & Premixes: Pourability and dosage repeatability.

FUNCTIONS AND APPLICATIONS of E460 CELLULOSE:
E460 Cellulose serves several technological functions in food products:

Bulking agent:
E460 Cellulose increases the volume of food products without adding calories.

Anti-caking agent:
E460 Cellulose prevents food particles from clumping together, for example in grated cheese or spice powders.

Stabilizer and emulsifier:
E460 Cellulose improves texture and consistency in processed foods.

Water retention agent:
E460 Cellulose binds moisture in baked goods and processed meat products.

Calorie-reducing filler:
E460 Cellulose is used in low-calorie or high-fiber food products.

Typical food products containing E460 Cellulose include: pharmaceutical tablets and capsules (as an excipient), grated cheese, baked goods, diet products, dietary supplements, and meat products.

PROPERTIES of E460 CELLULOSE:
E460 Cellulose is a white fine crystalline powder, odorless and tasteless, made from free-flowing non-fibrous particles and compressed by its self-adhesion effects.
E460 Cellulose can be rapidly dispersed in water into the tablet, but insoluble in water, dilute acid or alkali solution, solution and most organic solvents, and can absorb water to swell.

KEY FEATURES of E460 CELLULOSE:
E460 Cellulose is partially depolymerized E460 Cellulose prepared by treating alpha-E460 Cellulose, obtained as a pulp from fibrous plant material, with mineral acids, and it appears as a fine white to off-white powder.
E460 Cellulose is used as a texturizer, an anti-caking agent, emulsifier in pasteurized cream, fermented milk, cheese, processed fruit, dried vegetables, etc.

INSTRUCTIONS FOR USE & PROCESS TIPS of E460 CELLULOSE:
E460 Cellulose is typically evenly distributed in the dry premix and dispersed into the water phase.
Particle size and surface properties are critical for the final mouthfeel and flow.
Shear and hydration time should be optimized for stability.
Anti-caking performance can be improved with silica or fatty acid salts (e.g., Mg stearate).

PROCESS COMPATIBILITY & STABILITY of E460 CELLULOSE:
Heat:
Chemically stable at typical process temperatures.
pH:
Inert over a wide pH range; partial hydrolysis may occur with prolonged treatment in strong acids/bases.
Shear:
Suspension stability increases at high shear; particle fracture is limited at extreme shear.

ORIGIN AND PRODUCTION of E460 CELLULOSE:
E460 Cellulose is the most abundant organic polymer on Earth and the primary structural component of plant cell walls.
For use as a food additive, E460 Cellulose is primarily sourced from wood pulp or cotton fibers, which are then refined to achieve a high level of purity.

STRUCTURE OF E460 CELLULOSE:
A naturally occurring polymer, it is composed of glucose units connected by a 1-4 beta glycosidic bond.
These linear cellulose chains are bundled together as microfibril spiralled together in plant cell walls.

Each microfibril exhibits a high degree of three-dimensional internal bonding resulting in a crystalline structure that is insoluble in water and resistant to reagents.
There are, however, relatively weak segments of the microfibril with weaker internal bonding.

These are called amorphous regions; some[citation needed] argue that they are more accurately called dislocations, because of the single-phase structure of microfibrils.
The crystalline region is isolated to produce microcrystalline cellulose.

SYNTHESIS OF E460 CELLULOSE:
E460 Cellulose is pure partially depolymerized cellulose synthesized from α-cellulose precursor.
E460 Cellulose can be synthesized by different processes such as reactive extrusion, enzyme mediated, mechanical grinding, ultrasonication, steam explosion and acid hydrolysis.

The latter process can be done using mineral acids such as H2SO4, HCl and HBr as well as ionic liquids.
The role of these reagents is to destroy the amorphous regions leaving the crystalline domains.
The degree of polymerization is typically less than 400.

E460 Cellulose particles with size lower than 5 μm must not be more than 10%.
Thermogravimetric analysis (TGA) and differential thermal analysis (DTA) or differential scanning calorimetry (DSC) are also important to predict the thermal behavior of the E460 Cellulose upon heat stresses.

PROPERTIES of E460 CELLULOSE:
Appearance
E460 Cellulose is a fine, white or almost white, odourless, free flowing crystalline powder.

Particle Size
Not less than 5 μm (not more than 10% of particles of less than 5 μm)

Solubility
In water
E460 Cellulose is insoluble in water, but can swell in water, dilute alkali and acids, and in most organic solvents.
Practically insoluble or insoluble in sodium hydroxide solution (concentration: 50 g NaOH/L)
E460 Cellulose forms colloidal solutions at the concentration below 1%, and generate thixotropic gels at the concentration above 1%.

In organic Solvents
E460 Cellulose is insoluble in ethanol, ether and dilute mineral acids.

PRODUCTION of E460 CELLULOSE:
E460 Cellulose is derived from plant sources, typically wood pulp or cotton.
The extraction process involves breaking down the plant material to isolate the E460 Cellulose fibers, which are then purified and processed into a fine, white powder.

SOURCE of E460 CELLULOSE:
E460 Cellulose is entirely plant-derived.
E460 Cellulose is produced by the controlled hydrolysis of high-purity alpha-cellulose obtained from natural sources, primarily wood pulp and cotton fibers.
The production process involves treating the fibrous plant material with dilute mineral acids to separate the acid-resistant microcrystalline portion from the amorphous regions.
Although the production process involves chemical modification (technically making it "processed"), the raw material originates entirely from plant cell walls.
No animal-derived components are used in the production of E460 Cellulose, making it suitable for vegetarian and vegan diets.

PHYSICAL AND CHEMICAL PROPERTIES
There are many specifications for E460 Cellulose, namely, Avicel PH101, PH102, PH103, PH 105, and their differences are the particle size and the moisture content level.
Of them, PH 102 has the largest particle, with an average particle diameter of 62μm; while PH 105 has the smallest particle, with an average particle size of 25μm.
And PH103 has a less moisture content.

USAGE AND DOSAGE of E460 CELLULOSE:
E460 Cellulose is widely used as the excipient of tablets are two specifications—PH 101 and PH 102, with good compressibility as well as adhesion, flow aid, disintegration and other effects.
They are especially suitable for the direct compression process.
The compressed tablets have good hardness and are easy to disintegrate.
E460 Cellulose presents the plastic deformation during pressurization.
Combined with the capillary action, E460 Cellulose is easy to draw water inside to destroy the binding force between particles, and to promote the disintegration of tablets.

BENEFITS and FUNCTIONS of E460 CELLULOSE:
Let’s see E460 Cellulose's benefits and functions in food categories.
Beverage
E460 Cellulose stabilizes the liquid, adds viscosity, improves texture, and increases dietary fiber content in beverages, like fruit beverages, soft drinks, nutrition drinks and instant drinks.

Bakery
E460 Cellulose retains water longer, reduces oil absorption, and strengthens dough structure while softens the dough structure.
And therefore prolong the shelf-life of donuts, bakery & pastries.
Also, E460 Cellulose ensures the smoothness of the glaze by creating networks between liquid and sugar in glazings, icings, and fillings.

Dairy
Generally, E460 Cellulose stabilizes emulsions and foam, adds creaminess, replaces fats and oils, acts as an anti-caking agent and flavor carrier, improves flowability and prevents ice crystal growth in frozen desserts, whipped toppings, chocolate milk, cheese, ice cream and so on.

Culinary
E460 Cellulose provides emulsion stability, forms gels, improves adhesion (icing), enables fat reduction, adds creaminess, modifies texture- thickens with favorable mouth feel in dressing, sauces, dips, soups.

Fried and Processed Food
E460 Cellulose can reduce oil intake and fat absorption by adding it to fried food.
In meat, E460 Cellulose enhances the mouth-feel and texture by providing a fat-like mouthfeel; also, it acts as an emulsifying, stabilizing and binding agent used together with hydrocolloids like sodium alginate and carrageenan.

Tablets
E460 Cellulose can be used as a binder in tablet manufacturing to increase tablet hardness & also improves the flow properties, such as in vitamin supplement tablets.

Cosmetics
Per the “European Commission database for information on cosmetic substances and ingredients”, E460 Cellulose acts as an absorbent, anticaking, bulking, emulsion stabilising, opacifying, stabilising, and viscosity controlling agent in cosmetics and personal care products.

Pharmaceuticals
E460 Cellulose is an excipient in the pharmaceutical industry as an adsorbent, suspending agent, diluent, disintegrating agent or binder in pills, tablets, capsules and etc.
E460 Cellulose can be used in both wet-granulation and direct-compression processes.

HOW IS E460 CELLULOSE MADE?
Generally, it is produced by the controlled hydrolysis of highly purified alpha-E460 Cellulose made from naturally occurring wood E460 Cellulose.

The following are the simple manufacturing process:
Step 1: Alpha-E460 Cellulose production
Alpha E460 Cellulose is the highest degree of polymerization and is the most stable among the three classes of E460 Cellulose: alpha, beta and gamma.
It is the major component of wood and paper pulp.
Three types of E460 Cellulose all have the same chemical structure but differ in DP: alpha-E460 Cellulose DP > 200; beta-E460 Cellulose DP 30-200; gamma-E460 Cellulose DP 10-30.
Alpha type can be separated from the other components by treating with 17.5% solution of sodium hydroxide as beta and gamma types are soluble while alpha is not.

Step 2: Hydrolysis
In plant fibers, microcrystalline E460 Cellulose accounts for about 70% (acid-insoluble), and the rest 30% is amorphous regions of E460 Cellulose (acid-soluble fraction).

When treated alpha-E460 Cellulose with a dilute mineral acid, e.g. hydrochloric acid to reduce the degree of polymerization, the acid-soluble fraction can be completely hydrolyzed and subsequently obtain the tiny, acid-resistant microcrystalline E460 Cellulose.

BENEFITS AND CHARACTERISTICS of E460 CELLULOSE:
E460 Cellulose offers many important advantages across industrial sectors.
One of its greatest benefits is that E460 Cellulose is a natural, renewable, biodegradable, and sustainable material derived from plants.
Unlike many synthetic polymers, E460 Cellulose has low environmental impact and contributes to the development of eco-friendly products.
Its high structural strength and chemical stability make E460 Cellulose valuable in both food and industrial systems.

In foods, E460 Cellulose improves texture, stability, and fiber content while reducing calorie density.
E460 Cellulose provides bulk and viscosity without significantly affecting flavor or odor.
In pharmaceuticals, E460 Cellulose demonstrates excellent tablet binding and disintegration performance.
Its compatibility with active pharmaceutical ingredients and low toxicity make E460 Cellulose one of the safest and most widely accepted excipients.

Another important characteristic is E460 Cellulose's resistance to digestion in the human gastrointestinal system.
Because it behaves as insoluble dietary fiber, E460 Cellulose can support digestive health and intestinal function.
E460 Cellulose also contributes to satiety and may help improve stool bulk.

BENEFITS of E460 CELLULOSE:
E460 Cellulose is a dietary fiber that is not digested by the human body but plays an important role in maintaining gastrointestinal health.
E460 Cellulose improves intestinal peristalsis, prevents constipation, and helps maintain healthy cholesterol levels.
Studies have shown that microcrystalline and powdered E460 Cellulose are partially fermented by the gut microbiota in the large intestine, which can have a positive impact on the microbiome balance.

TYPES of E460 CELLULOSE:
E460(i): Microcrystalline E460 Cellulose
E460(ii): Powdered E460 Cellulose
Microcrystalline E460 Cellulose is produced through partial depolymerization of E460 Cellulose using mineral acids, while powdered E460 Cellulose is mechanically processed purified E460 Cellulose.

PHYSICAL and CHEMICAL PROPERTIES of E460 CELLULOSE:
Appearance: A fine white or almost white odorless powder
Particle size: 98% pass 120 mesh
Assay (as α- cellulose, dry basis): ≥97%
Water-soluble matter: ≤ 0.24%
Sulphated ash: ≤ 0.5%
pH (10% solution): 5.0- 7.5
Molecular Formula: (C12H20O10)n
EINECS: 232-674-9
Appearance:
White Powder

CAS No.: 9004-34-6
Appearance: A fine white or almost white odorless powder
Particle size: 98% pass 120 mesh
Assay (as α- cellulose, dry basis): ≥97%
Water-soluble matter: ≤ 0.24%
Sulphated ash: ≤ 0.5%
pH (10% solution): 5.0- 7.5
Molecular Formula: (C6H10O5)n, “n” represents the number of repeating glucose units.
Molecular Weight: Varies depending on the degree of polymerization,
typically ~36,000 to 100,000 g/mol (average range)

Chemical Name: Cellulose
Food Additive Number: E460
CAS Number: 9004-34-6
EC Number: 232-674-9
Molecular Formula: (C6H10O5)n
Molecular Weight: Variable polymer; repeating unit approximately 162.14 g/mol
Chemical Class: Polysaccharide, natural biopolymer
Appearance: White or almost white powder, fibrous material, or granules
Odor: Odorless
Taste: Tasteless

Origin: Plant-derived natural polymer
Appearance: White to off-white powder, granules, or fibrous solid
Odor: Odorless and tasteless
Solubility in Water: Insoluble in water
Solubility in Organic Solvents: Insoluble in most organic solvents
Water Behavior: Swells in water without dissolving
Hygroscopicity: Hygroscopic to a limited extent
Mechanical Strength: High mechanical strength

Tensile Strength: High tensile strength due to hydrogen bonding
Biodegradability: Biodegradable and renewable material
Toxicity: Non-toxic and environmentally friendly
Stability: Stable under normal conditions
Chemical Behavior: Chemically inert in many applications
Resistance to Oils and Fats: Resistant to oils and fats
Bulking and Texturizing Properties: Excellent bulking and texturizing properties
Compressibility: Good compressibility for tablet manufacturing

Anti-Caking Performance: Excellent anti-caking performance
Density: Low density material
Crystallinity: High crystallinity depending on source and processing
Microbial Resistance: Resistant to microbial degradation under dry conditions
Hydrolysis: Can be hydrolyzed by strong acids
Thermal Behavior: Decomposes before melting at high temperatures
Thermal Decomposition: Generally begins above 260°C
Adsorption Capability: Good adsorption capability

Surface Area: High surface area in microcrystalline grades
Flow Properties: Good flow properties in powdered form
Compatibility: Compatible with many pharmaceutical excipients and food ingredients
Binding Capability: Excellent binding capability
Moisture Retention Properties: Good moisture retention properties
Viscosity Control: Provides viscosity control in suspensions
Dietary Fiber Source: Insoluble dietary fiber source

Digestive Resistance: Resistant to digestive enzymes in humans
pH Behavior: Neutral pH behavior
Suspension Stabilization Properties: Good suspension stabilization properties
Caloric Contribution: Low caloric contribution in foods
Allergenic Properties: Non-allergenic in most applications
Chemical Resistance: Resistant to weak alkalis and dilute acids
Degree of Polymerization: Varies depending on source and processing
Crystallinity Index: May vary significantly

Morphology: Fibrous morphology contributes to structural reinforcement properties
Function: Bulking agent, texture regulator, stabilizer, anti-caking agent, oil substitute.
Chemical Name: Microcrystalline Cellulose (MCC)
E Code / INS: E460 / INS 460
CAS No: 9004-34-6
Appearance: White, odorless, fine powder.
Resolution: It is insoluble in water; it disperses in water to form a suspension.
Particle Size: Depending on the application, there are different d 50 classes (which affect flow and mouth sensation).
Typical Dosage Range: Volume/texture: 0.3–3.0% • Anti-caking/flow: 0.2–1.0% • Oil substitute: 0.5–2.0%

FIRST AID MEASURES of E460 CELLULOSE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of E460 CELLULOSE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of E460 CELLULOSE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of E460 CELLULOSE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of E460 CELLULOSE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of E460 CELLULOSE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available