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E462 Ethyl cellulose is used in adhesives, ceramics, electronics, and as a rheology modifier in various formulations.
E462 Ethyl cellulose serves as a lubricant in chromatography and a stabilizer in emulsions and suspensions.
E462 Ethyl cellulose is majorly utilized used as a thin-film coaterial.
CAS Number: 9004-57-3
EC Number: 618-384-9
Molecular Formula: Variable polymer structure; commonly represented as [C6H7O2(OC2H5)3−x(OH)x]n
x = degree of ethyl substitution
n = polymerization degree
Molecular Weight: Variable depending on degree of polymerization and substitution
~45,000 – 250,000 g/mol
Some industrial grades may exceed this range.
SYNONYMS:
Cellulose, ethyl ether, ethylated cellulose, ethylcellulose, E462, Ethyl Cellulose, Ethylcellulose, Cellulose Ethyl Ether, Ethocel, E462, Ethylated Cellulose, Ethyl Hydroxy Cellulose, Ethyl Ether of Cellulose, Modified Cellulose Ether, EC Polymer, Cellulose Ethylate, Ethylated Polysaccharide, Food Additive E462, ampacet E/C, aquacoat, aquacoat ECD 30, aqualon ethylcellulose, cellulose ethyl, cellulose ethyl ether, cellulose ethylate, cellulose, ethyl ester, cellulose, ethyl ether, 2-[4,5- diethoxy-2-(ethoxymethyl)-6-methoxyoxan-3-yl]oxy-6-(hydroxymethyl)-5-methoxyoxane-3,4-diol, ethocel, ethocel 150, ethocel MED, ethocel STD, ethyl cellulose FCC, ethylcellulose, nixon e/c, surelease, triethyl cellulose, Ethylcellulose, 618-384-9, Aquacoat ecd, Cellulose ethyl, Cellulose, ethyl ether, DTXSID0049608, Ethyl Cellulose, Ethylcellulose, Unspecified, RefChem:596575, SPT 50 cps, ethyl-cellulose, ethylcellulosum, etilcelulosa, 7Z8S9VYZ4B, 9004-57-3, Cellulose ethyl ether, Cellulose, ethyl ester, E-462, Ethocel, Ethylcelluloses, INS-462, Ampacet E/C, Cellulose ethylate, Cellulose, triethyl ether, Ethocel 150, Ethocel 890, Ethocel MED, Ethocel STD, G 200, Nixon E/C, SPT 50CPS, T 100, Triethyl cellulose, 19B35R0C0W, 3DYK7UYZ62, 589D1IWM11, 6I475159RA, Aquacoat ECD 30, Aquacoat ECD 30FMC, B8GRN8XBC5, BJG0S321QY, ET 100 (cellulose derivative), ETS (Polysaccharide), Ethocel E50, Ethocel E7, Ethocel N10, Ethocel N200, Ethocel N7, G 200 (polysaccharide), G 50 (Polysaccharide), HZJ2V81RYU, KC5472WRJK, MX37N1DUF3, T 100 (Polysaccharide), V7AD894FAZ, YV4VDW9SQS
E462 Ethyl cellulose is a derivative of cellulose in which some of the hydroxyl groups on the repeating glucose units are converted into ethyl ether groups.
The number of ethyl groups might not be exactly the same.
E462 Ethyl cellulose depend on different producer’s technology.
E462 Ethyl cellulose is one of few non-toxic films and thickeners which are not water soluble.
This is a good property which finds E462 Ethyl cellulose's application in safeguarding ingredients from water.
The ethyl groups of E462 Ethyl cellulose and its mixed ethers have stronger hydrophobicity than the methyl groups of mE462 Ethyl cellulose series substances.
Thus, E462 Ethyl cellulose is in the industry a typical cellulose ether soluble in organic solvents but insoluble in water.
When the degree of substitution of ethyl is about 0.7-1.7, E462 Ethyl cellulose is soluble in water; while it is higher than 1.5, E462 Ethyl cellulose can be soluble in organic solvents.
The DS value of E462 Ethyl cellulose manufactured in different places is a little different.
E462 Ethyl cellulose is soluble in the mixed solvent of hydrocarbon and a lower alcohol, ketones, and ethers with low molecular weight.
E462 Ethyl cellulose is usually white or slightly yellow.
In order to prevent the ethoxy from autoxidation reaction and producing peroxides when irradiated by light, antioxidants are often added as stabilizers.
Under normal conditions, E462 Ethyl cellulose doesn’t dissolve in water.
How ever E462 Ethyl cellulose is soluble in many organic solvents are utilized as tablets, granules of the adhesive, is able to increase the hardness of tablets to reduce friability tablets.
E462 Ethyl cellulose could be applied as film-forming agent to improve the appearance of tablets, isolated taste, to avoid the failure of water-sensitive drugs to prevent the influx of metamorphic change agents, promoting the safe storage of tablets, but also is able be utilized as reinforcing material for sustained release tablets.
E462 Ethyl cellulose is a hydrophobic cellulose ether derived from natural cellulose in which hydroxyl groups are partially substituted with ethoxy groups.
E462 Ethyl cellulose is water-insoluble but soluble in many organic solvents.
E462 Ethyl cellulose is a biodegradable polymer derived from cellulose that possesses non-toxic properties and is insoluble in water.
E462 Ethyl cellulose is a synthetically processed additive made from cellulose, the main structural substance in plants and wood.
E462 Ethyl cellulose is commercially extracted from wood or other plant fibers and subsequently chemically ethylated.
The result is a white powder without odor or taste.
Although the base is natural, the end product is therefore indeed chemically processed.
E462 Ethyl cellulose is generated by converting a variable number of hydroxyl groups on the repeating glucose units to ethyl ether groups
E462 Ethyl cellulose is obtained directly from plant fibers (pulp, cotton) and then chemically modified.
Cellulose, a mixture of many individual components, forms the supporting structure of plant cells and is therefore found in all plants.
Cellulose is indigestible for the human body.
The food industry constantly seeks ingredients that can improve texture, enhance stability, and extend the shelf-life of products.
E462 Ethyl cellulose (CAS 9004-57-3) has proven to be a valuable food additive (E462) due to its versatile functional properties.
E462 Ethyl cellulose's ability to act as an emulsifier, thickener, and stabilizer makes it a sought-after ingredient in a wide range of food products.
E462 Ethyl cellulose's non-toxic nature and water-insolubility are particularly advantageous, allowing it to safeguard ingredients from moisture and improve the overall structure and mouthfeel of foods.
Whether you are developing baked goods, confectionery, or processed foods, incorporating E462 Ethyl cellulose can lead to noticeable improvements in product consistency and appeal.
E462 Ethyl cellulose is insoluble in water but soluble in organic solvents such as ethanol, acetone, and chloroform.
E462 Ethyl cellulose forms films and is resistant to moisture, making it useful as a coating and controlled-release agent.
E462 Ethyl cellulose's main functions as a food additive are as a thickener, stabilizer, emulsifier, and coating agent.
In the European Union, E462 Ethyl cellulose was authorized as a food additive after evaluations by EFSA (European Food Safety Authority) and WHO (World Health Organization).
It is important to note that although E462 Ethyl cellulose is a cellulose derivative, it is not considered a natural additive but a semi-synthetic one.
E462 Ethyl cellulose (EC) is a white to off-white, free-flowing powder derived from cellulose, where some hydroxyl groups on the repeating glucose units are substituted with ethyl ether groups.
E462 Ethyl cellulose is a non-toxic, hydrophobic polymer that is insoluble in water but soluble in various organic solvents.
The food additive E462, known as E462 Ethyl cellulose, is a semi-synthetic derivative of cellulose, the most abundant polysaccharide in nature.
E462 Ethyl cellulose is obtained by reacting cellulose with ethyl chloride under alkaline conditions, introducing ethyl groups into the cellulose structure.
Industrially, cellulose is extracted from wood or cotton, purified, and treated with sodium hydroxide to form alkali cellulose, which then reacts with ethyl chloride.
The final product, E462 Ethyl cellulose is a white or slightly yellowish powder, odorless and tasteless.
E462 Ethyl cellulose is a chemically modified form of cellulose, a natural polymer derived from plant fibers.
E462 Ethyl cellulose is essentially a chemically modified form of cellulose.
E462 Ethyl cellulose is synthesised by reacting cellulose with ethylated alcohol in the presence of sulphuric acid as a catalyst.
E462 Ethyl cellulose is a non-toxic, biologically inert, white or off-white powder.
E462 Ethyl cellulose is almost insoluble in water, but soluble in many organic solvents.
E462 Ethyl cellulose is a derivative of cellulose.
E462 Ethyl cellulose is a chemically modified cellulose derivative produced by reacting purified cellulose with ethyl chloride under alkaline conditions.
E462 Ethyl cellulose belongs to the cellulose ether family and is widely used in food, pharmaceutical, coating, cosmetic, printing, and industrial applications because of its excellent film-forming ability, water resistance, stability, and thermoplastic properties.
Unlike many other cellulose derivatives, E462 Ethyl cellulose is insoluble in water but soluble in various organic solvents.
This hydrophobic behavior makes E462 Ethyl cellulose especially useful in protective coatings, controlled-release pharmaceutical systems, flavor encapsulation, printing inks, adhesives, and moisture-resistant films.
E462 Ethyl cellulose forms tough, flexible, transparent films with excellent mechanical strength and chemical stability.
Because of its low toxicity, biodegradability, and compatibility with many materials, E462 Ethyl cellulose is considered one of the most versatile cellulose-based polymers used in industrial formulations.
E462 Ethyl cellulose is an approved food additive used as a carrier, binder, and filler in food supplements and pharmaceutical products.
E462 Ethyl cellulose is an approved food additive used as a carrier, binder, and filler in food supplements and pharmaceutical products.
E462 is the European designation for E462 Ethyl cellulose, a semi-synthetic additive derived from natural cellulose.
Cellulose is a plant-based dietary fibre found in the cell walls of plants.
During the production of E462 Ethyl cellulose, the hydroxyl groups of cellulose are replaced with ethyl groups, resulting in a water-insoluble, thermoplastic polymer.
In the food industry, E462 Ethyl cellulose is primarily used as a carrier substance, binder, and filler.
Since E462 Ethyl cellulose is neither digested nor absorbed by the human body, it is considered a calorie-free dietary fibre.
In the European Union, E462 Ethyl cellulose is approved for specific applications under Regulation (EC) No. 1333/2008.
E462 Ethyl cellulose, or ethylcellulose, also known as its abbreviation EC.
E462 Ethyl cellulose is made from cellulose and commonly used as a coating in pharmaceutical formulations.
The European food additive number for E462 Ethyl cellulose is E462.
E462 Ethyl cellulose is an ether of cellulose Or it is a water insoluble polymer derived from cellulose where some of the hydroxyl groups are replaced by ethyl ether groups.
E462 Ethyl cellulose, also designated as E462, is one of the food additives used mainly as a thickener, stabilizer and gelling agent.
E462 Ethyl cellulose is a substance obtained from cellulose, a naturally occurring polysaccharide present in the cell walls of plants.
E462 Ethyl cellulose is in the form of a white powder and is virtually odorless and tasteless, making it an ideal ingredient for many food products.
E462 Ethyl cellulose is a derivative of cellulose in which some of the hydroxyl groups on the repeating glucose units are converted into ethyl ether groups.
The number of ethyl groups can vary depending on the manufacturer.
Food grade E462 Ethyl cellulose is one of few non-toxic films and thickeners which are not water-soluble.
This property allows it to be used to safeguard ingredients from water.
E462 Ethyl cellulose is a semisynthetic food additive, with emulsifying, stabilizing, diluent for other colorants and food additives and thickening role, obtained from cellulose.
E462 Ethyl cellulose is used as a substance-support for other food additives.
E462 Ethyl cellulose is insoluble and indigestible, having a detoxifying role for the digestive tract.
E462 Ethyl cellulose is a powder, insoluble in water, but soluble in some organic solvents, which is used in the quantities on the recipes in dairy products, in sweets, creams, emulsified fat spreads with or without flavors, sauces, snacks, ice creams, processed, preserved fruits and vegetables, meat products, fish, eggs, spices, soups, broths, salads, edible membranes, vegetable protein products, nutritional supplements, mustard, alcoholic and non-alcoholic beverages, dietetic products etc.
E462 Ethyl cellulose is a derivative of cellulose in which some of the hydroxyl groups of the cellulose chain have been replaced with ethyl groups.
This modification gives E462 Ethyl cellulose unique properties, such as being insoluble in water but soluble in certain organic solvents.
E462 Ethyl cellulose is widely used in the food, pharmaceutical, and cosmetic industries as a thickening agent, stabilizer, film-former, and coating agent.
E462 Ethyl cellulose is also valued for its ability to control the release of active ingredients in pharmaceutical applications.
USES and APPLICATIONS of E462 ETHYL CELLULOSE:
As a cellulose ether, E462 Ethyl cellulose finds widespread utilization across multiple industries.
E462 Ethyl cellulose is extensively used in pharmaceutical formulations, particularly for controlled-release coatings of tablets and capsules.
E462 Ethyl cellulose acts as a rate-controlling membrane, allowing gradual release of active ingredients.
In the food industry, E462 Ethyl cellulose is used as a coating agent, stabilizer, and texturizer, although its use is more limited compared to other cellulose derivatives due to its insolubility in water.
In coatings and paints, E462 Ethyl cellulose is used as a binder and film former, providing durability, adhesion, and resistance to environmental factors.
E462 Ethyl cellulose is also widely used in inks, varnishes, and printing formulations.
In cosmetics, E462 Ethyl cellulose functions as a thickener, film former, and stabilizer in products such as nail polishes, hair sprays, and creams.
In industrial applications, E462 Ethyl cellulose is used in adhesives, ceramics, electronics, and as a rheology modifier in various formulations.
In scientific research, E462 Ethyl cellulose demonstrates remarkable versatility.
E462 Ethyl cellulose serves as a lubricant in chromatography and a stabilizer in emulsions and suspensions.
E462 Ethyl cellulose is majorly utilized used as a thin-film coaterial.
E462 Ethyl cellulose can be applied as a food additive too.
E462 Ethyl cellulose can also be mainly utilized as a thin-film coating material for coating paper, vitamin and medical pills, and for thickeners in cosmetics and in industrial processes.
E462 Ethyl cellulose is widely used in pharmaceuticals, coatings, food applications (as E462), and industrial formulations due to its film-forming and barrier properties.
E462 Ethyl cellulose is primarily used in dietary supplements and encapsulated flavorings.
E462 Ethyl cellulose acts as a binder, filler, and protective coating.
E462 Ethyl cellulose also stabilizes water-oil mixtures.
E462 Ethyl cellulose is used as a thickener, bulking agent, emulsifier, stabilizer, and anti-caking agent.
E462 Ethyl cellulose is found in various processed foods, but it is primarily used as a coating and binding agent in pharmaceutical products and dietary supplements (think of tablet coatings).
In principle, E462 Ethyl cellulose may be used in all food and beverages in the food industry (quantum satis, or: as much as is necessary), but in practice, it is used in relatively few food products.
Food Additive: E462 Ethyl cellulose is used to improve the texture, stability, and appearance of various food products.
Stabilizer: E462 Ethyl cellulose helps stabilize emulsions and suspensions, ensuring uniformity and preventing separation of ingredients.
Thickener:E462 Ethyl cellulose acts as an effective thickening agent in sauces, soups, and other food products, providing the desired consistency without altering taste.
Coating Agent: E462 Ethyl cellulose is used as a coating agent in the food industry to provide a protective layer, enhancing the shelf life and appearance of food products.
Film Former: E462 Ethyl cellulose is used in the production of edible films and coatings, providing a barrier against moisture and oxygen.
Sustained Release: In the pharmaceutical industry, E462 Ethyl cellulose is used in controlled release formulations to modulate the release rate of active ingredients.
Gluten-Free: E462 Ethyl cellulose is naturally gluten-free, making it suitable for gluten-free food products.
E462 Ethyl cellulose's use is permitted in a wide variety of foods, especially those requiring texture or coating.
E462 Ethyl cellulose is widely used as a film-former, binder, thickener, and stabilizer in pharmaceutical, food, cosmetic, and industrial applications.
Pharmaceuticals: E462 Ethyl cellulose is used Tablet coatings, controlled-release matrices
Food Industry: E462 Ethyl cellulose, protective coating for ingredients
Cosmetics: E462 Ethyl cellulose is used thickener in nail polish, hair products
Industrial: E462 Ethyl cellulose is used binder in ceramics, coatings for paper, inks, adhesives
Specialty Coatings: E462 Ethyl cellulose is used hot-melt adhesives, transfer inks
E462 Ethyl cellulose is widely used in the food and pharmaceutical industries due to its versatile functional properties.
Moreover, E462 Ethyl cellulose acts as a binder in tablet and capsule manufacturing, a protective coating for food products, and a binding agent in adhesive production.
In pharmaceuticals, E462 Ethyl cellulose is highly valued because it enables precise control of drug release profiles.
E462 Ethyl cellulose can significantly improve stability, taste masking, and protection of sensitive active compounds.
Its low toxicity, odorless nature, and broad regulatory acceptance make E462 Ethyl cellulose suitable for food, cosmetic, and pharmaceutical applications.
Because it is derived from cellulose, E462 Ethyl cellulose is also partially renewable and more environmentally favorable than many petroleum-based polymers.
E462 Ethyl cellulose is mainly used as a thin-film coating material for coating paper, vitamin and medical pills, and for thickeners in cosmetics and in industrial processes.
Food grade E462 Ethyl cellulose is one of few non-toxic films and thickeners which are not water soluble.
This property allows E462 Ethyl cellulose to be used to safeguard ingredients from water.
E462 Ethyl cellulose is also used as a food additive as an emulsifier.
E462 Ethyl cellulose is used as a stabiliser and thickener for foods and diluent in food marking inks.
E462 Ethyl cellulose is widely used in various industries due to its unique properties.
E462 Ethyl cellulose is most commonly used as a stabilizer, thickener, release agent and film former in the pharmaceutical industry.
In the food industry, E462 Ethyl cellulose is used as an additive in food to increase its stability, consistency and shelf life.
E462 Ethyl cellulose is also a component of some cosmetic products and toiletries.
In addition, E462 Ethyl cellulose is found in products such as paints, varnishes, coatings, adhesives, printing inks and many others.
Notably, E462 Ethyl cellulose also serves as a stabilizing agent in the production of emulsion polymers and as a film-forming agent for medical device coatings.
E462 Ethyl cellulose is widely used in pharmaceutical applications because of its controlled-release and film-forming properties.
E462 Ethyl cellulose is commonly used in tablet coatings, sustained-release drug delivery systems, microencapsulation technologies, and protective pharmaceutical films.
Its water-insoluble nature allows E462 Ethyl cellulose to control drug release rates and improve stability of active ingredients.
In the food industry, E462 Ethyl cellulose functions as a coating agent, stabilizer, thickener, binder, and encapsulating material.
E462 Ethyl cellulose is used in flavor encapsulation, confectionery coatings, chewing gum bases, edible films, and moisture-resistant food coatings.
E462 Ethyl cellulose can improve texture stability and protect sensitive ingredients from moisture and oxidation.
In printing inks, paints, and coatings, E462 Ethyl cellulose serves as a binder, viscosity modifier, film former, and rheology control agent.
E462 Ethyl cellulose improves adhesion, durability, flexibility, and solvent resistance in industrial coatings and specialty printing systems.
E462 Ethyl cellulose is also extensively used in adhesives, lacquers, varnishes, and specialty plastics because of its thermoplastic properties and compatibility with hydrophobic systems.
In cosmetics and personal care products, E462 Ethyl cellulose is used in nail polishes, hair sprays, creams, lotions, and film-forming cosmetic products.
E462 Ethyl cellulose contributes to texture improvement, durability, and moisture resistance.
Industrial applications of E462 Ethyl cellulose include: protective coatings, flexible packaging, ceramic binders, electronic materials, battery technologies, specialty membranes, filtration systems, 3D printing materials, controlled-release agricultural formulations.
While the exact mechanism of action of E462 Ethyl cellulose remains not entirely elucidated, its effectiveness is attributed to its ability to form hydrogen bonds with water molecules.
E462 Ethyl cellulose is a powder, insoluble in water, but soluble in some organic solvents, which is used in the quantities on the recipes in dairy products, in sweets, creams, emulsified fat spreads with or without flavors, sauces, snacks, ice creams, processed, preserved fruits and vegetables, meat products, fish, eggs, spices, soups, broths, salads, edible membranes, vegetable protein products, nutritional supplements, mustard, alcoholic and non-alcoholic beverages, dietetic products etc.
This capability enables the creation of a protective layer around active ingredients, safeguarding them from degradation and extending the product′s shelf life.
Food Industry: E462 Ethyl cellulose (E462) is used as an emulsifier, thickening agent and stabilizer in certain food products.
Its water-insoluble nature allows E462 Ethyl cellulose to be used in coatings for food products, such as in the production of encapsulated flavors or vitamins.
Pharmaceuticals: In the pharmaceutical industry, E462 Ethyl cellulose is widely used as a film-forming agent in controlled-release tablets and capsules.
E462 Ethyl cellulose is also used as a binder in tablet formulations and to improve the stability of drug suspensions.
Cosmetics: In cosmetics, E462 Ethyl cellulose is used as a film-former and thickening agent in products such as lotions, creams, and hair gels.
E462 Ethyl cellulose helps to improve product texture and stabilize emulsions.
Additionally, E462 Ethyl cellulose acts as a barrier between the active ingredients and the environment, shielding them from moisture and other detrimental external factors.
In food, E462 Ethyl cellulose can be used for binding, emulsifying, film forming and flavor fixatives.
Mostly E462 Ethyl cellulose is used in pharmaceuticals as a coating in the formulations of tablets and capsules as it can help mask the non-desirable taste, protect the active ingredients and control the drug release.
E462 Ethyl cellulose is also used as a food additive as an emulsifier.
E462 Ethyl cellulose is mainly used as a thin-film coating material for coating paper, vitamin and medical pills, and for thickeners in cosmetics and in industrial processes.
E462 Ethyl cellulose is commonly used as a coating material for tablets and capsules, as it provides a protective barrier that prevents the active ingredients from being released too quickly in the digestive system.
E462 Ethyl cellulose is also used as a binder, thickener, and stabilizer in a variety of food, cosmetic, and pharmaceutical products.
Cosmetics uses of E462 Ethyl cellulose: Per “European Commission database for information on cosmetic substances and ingredients”, E462 Ethyl cellulose can work as a binding, film forming, and viscosity controlling agent in cosmetic and personal care products.
-E462 Ethyl cellulose is widely used in the food industry.
E462 Ethyl cellulose can be used in products such as:
Sauces:
The addition of E462 Ethyl cellulose helps maintain the homogeneous consistency of sauces and prevents ingredients from separating.
Fruit mousses:
E462 Ethyl cellulose allows fruit mousses to have a smooth and creamy texture.
Jellies:
E462 Ethyl cellulose acts as a thickener and stabilizer in the production of jellies, giving them the right texture.
Puddings:
E462 Ethyl cellulose is often used to gel puddings, giving them the right texture and consistency.
-Food uses of E462 Ethyl cellulose:
Some approved uses are listed by the FDA and EFSA as follows:
FDA
When evaluated the safety of EC from Dow Wolff Cellulosics (Dow) in food in 2013, the FDA approved the uses in viscosity modification, thickening, film-forming, stabilization, acting as a filler, and for thermal gelation in following foods at levels ranging from 0.0075 to 5%:
Grain products
Vegetables
Fruits
Milk and milk products
Legumes
Nuts and seeds
Fats and oils
Sugars and sweets
Beverages
EFSA
E462 Ethyl cellulose can be used as a coating agent for solid dietary food supplements and as a micro-encapsulating agent for fixing colours and flavouring agents.
-Use of E462 Ethyl cellulose in Food and Dietary Supplements:
Capsule shells:
E462 Ethyl cellulose is used as a shell material for hard capsules in dietary supplements.
Tablet coatings:
In the pharmaceutical industry, E462 Ethyl cellulose serves as a film coating for tablets to protect the active ingredient from moisture or to enable delayed release.
Binder and filler:
E462 Ethyl cellulose improves the consistency and processability of foods and supplements.
Fat replacer:
Research is exploring E462 Ethyl cellulose as a structuring agent for vegetable oils (so-called oleogels) to replace saturated fats.
-Sustained-release Dosage uses of E462 Ethyl cellulose:
E462 Ethyl cellulose is commonly used as a film coating in sustained-release dosage formulations as it does not swell and impedes drug release when in contact with water due to its water insoluble property.
E462 Ethyl cellulose helps release the drug slowly, therefore it increases the duration of drug action and decreases dosing frequency of some water-soluble drugs, and maintain a more uniform drug level in the human body.
In this way, E462 Ethyl cellulose improves treatment efficacy and a lower incidence of adverse reactions caused by a more uniform drug level.
Water-soluble coating cannot be used in some applications because of the processing problems or water sensitivity of the active ingredient.
-Pharmaceuticals use of E462 Ethyl cellulose:
E462 Ethyl cellulose is a semi-synthetic polymer material which has good thermal stability, biocompatibility and biodegradability in vivo, and has good film-forming properties.
As a widely used drug carrier, E462 Ethyl cellulose plays a protective role in the prevention of pollution and destruction during the preservation, transportation and release rate of drugs.
Protection
E462 Ethyl cellulose can be used to coat ingredients to prevent them from reacting with other materials.
E462 Ethyl cellulose can prevent discoloration of easily oxidizable substances such as ascorbic acid, allowing granulations for easily compressed tablets and other dosage forms.
BENEFITS AND CHARACTERISTICS of E462 ETHYL CELLULOSE:
One of the major advantages of E462 Ethyl cellulose is its excellent water resistance combined with strong film-forming capability.
This makes it highly valuable in controlled-release systems and protective coatings where moisture protection is essential.
E462 Ethyl cellulose produces durable, flexible, transparent films with good mechanical strength and chemical stability.
Its hydrophobic behavior allows it to act as an effective moisture barrier and oxygen barrier in packaging and coating systems.
Another important characteristic is E462 Ethyl cellulose's thermoplastic nature, allowing easy processing into films, coatings, fibers, and molded structures.
E462 Ethyl cellulose also demonstrates excellent compatibility with many organic solvents, resins, oils, waxes, and plasticizers.
PRODUCTION of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose is produced by treating cellulose with ethyl chloride, resulting in the substitution of some of the hydroxyl groups with ethyl groups.
This modification enhances E462 Ethyl cellulose's solubility in organic solvents and imparts unique functional properties.
ORIGIN AND PRODUCTION of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose is produced industrially by reacting alkali cellulose with chloroethane (ethyl chloride).
The raw material, cellulose, is typically sourced from wood pulp or cotton linters.
The final product, E462 Ethyl cellulose, is a white to off-white powder or granule that is insoluble in water but soluble in various organic solvents.
PHYSICAL AND CHEMICAL PROPERTIES of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose appears as a white to light tan, odorless, tasteless powder or granules.
E462 Ethyl cellulose is insoluble in water but readily soluble in organic solvents such as ethanol, methanol, chloroform, and ethyl acetate.
This hydrophobic nature distinguishes E462 Ethyl cellulose from many other cellulose derivatives.
It does not have a true melting point; instead, E462 Ethyl cellulose softens and decomposes when heated, typically above 160–200°C depending on grade.
E462 Ethyl cellulose has excellent thermal stability compared to other cellulose ethers.
E462 Ethyl cellulose forms strong, flexible, and transparent films, making it highly suitable for coating applications.
E462 Ethyl cellulose is chemically stable, non-ionic, and resistant to acids and alkalis within a moderate pH range.
E462 Ethyl cellulose shows good compatibility with plasticizers, resins, and other polymers.
The viscosity of E462 Ethyl cellulose solutions depends on molecular weight and substitution degree.
E462 Ethyl cellulose has low moisture absorption and provides excellent barrier properties against oxygen, oils, and moisture.
CHARACTERISTICS AND FUNCTIONAL PROPERTIES of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose has several defining characteristics:
*Water insolubility (hydrophobic polymer)
*Solubility in organic solvents
*Excellent film-forming capability
*Strong binding and coating properties
*Good thermal stability
*Low permeability to moisture and gases
*Non-ionic and chemically stable
*Good mechanical strength and flexibility
PERFORMANCE PROPERTIES of E462 ETHYL CELLULOSE:
Film Formation:
E462 Ethyl cellulose forms tough, flexible, transparent films with good barrier properties.
Solubility:
E462 Ethyl cellulose is soluble in organic solvents like alcohols, ethers, and chlorinated hydrocarbons; insoluble in water, glycerin, and propylene glycol.
Thermal Stability:
Thermoplastic, stable up to ~150°C; burns out cleanly in high-temperature applications (e.g., ceramics).
Adhesion:
Excellent adhesion to substrates like paper, plastic, and metal foils.
Hydrophobicity:
E462 Ethyl cellulose protects moisture-sensitive materials in coatings and encapsulates.
FUNCTIONAL ROLES OF E462 ETHYL CELLULOSE IN FOOD PRODUCTS:
The applications of E462 Ethyl cellulose in the food industry are diverse and impactful:
Thickener and Stabilizer:
E462 Ethyl cellulose helps to increase the viscosity of liquid-based food products, preventing separation and maintaining a smooth, consistent texture.
This is particularly useful in sauces, dressings, and dairy products.
Businesses looking to improve product texture can confidently buy E462 Ethyl cellulose from our extensive supply.
Emulsifier:
E462 Ethyl cellulose aids in the formation and maintenance of emulsions, ensuring that oil and water phases remain uniformly dispersed in products like mayonnaise and salad dressings.
Binder:
E462 Ethyl cellulose can act as a binder in processed foods, helping to hold ingredients together, especially in products like meat alternatives or snack bars.
Coating Agent:
Similar to its pharmaceutical applications, E462 Ethyl cellulose can be used as a protective coating for certain food items, such as confectionery or dried fruits, to prevent moisture ingress and maintain crispness.
PRODUCTION PROCESS of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose is produced by reacting cellulose, typically derived from wood pulp or cotton, with ethyl chloride under alkaline conditions.
This reaction replaces hydroxyl groups in the cellulose with ethyl groups, producing E462 Ethyl cellulose.
The resulting material is purified and processed into a fine powder or granules suitable for industrial use.
Extraction of Cellulose:
Cellulose is extracted from plant sources such as wood or cotton.
This process may include maceration and chemical treatment with alkaline solutions to remove lignin and hemicellulose.
Chemical Modification:
The extracted cellulose is then subjected to an ethylation process, where ethyl groups (-C₂H₅) are added to the cellulose using an ethylation reagent such as ethyl chloride in the presence of a solvent, typically an alcohol.
This process transforms cellulose into ethylcellulose, altering its physical and chemical properties.
Purification:
The produced ethylcellulose is purified to remove any impurities and chemical residues.
This may involve washing and filtration to ensure the quality of the final product.
Drying and Milling:
Once purified, the ethylcellulose is dried and milled into a fine powder to facilitate its use in formulations.
Quality Control and Packaging:
Finally, ethylcellulose undergoes quality control checks to verify its purity and functional properties.
After analysis, E462 Ethyl cellulose is packaged for distribution and use.
BENEFITS of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose offers significant advantages due to its hydrophobic and film-forming nature.
E462 Ethyl cellulose provides excellent moisture resistance, making it ideal for protective coatings.
In pharmaceuticals, E462 Ethyl cellulose enables precise control over drug release profiles.
E462 Ethyl cellulose improves product stability, enhances mechanical strength, and protects sensitive ingredients from environmental degradation.
Its non-toxic and inert nature makes E462 Ethyl cellulose suitable for use in food, pharmaceutical, and cosmetic applications.
E462 Ethyl cellulose is also biodegradable to some extent and derived from renewable cellulose sources.
CHEMICAL COMPOSITION AND STRUCTURE of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose is formed by the chemical reaction of cellulose with ethyl chloride in the presence of an alkaline catalyst.
This process replaces the hydroxyl groups (-OH) in the cellulose with ethyl groups (-C₂H₅).
The degree of ethyl substitution determines its solubility and performance in different applications.
E462 Ethyl cellulose's structure makes it non-ionic, which enhances its stability in various formulations.
E462 ETHYL CELLULOSE AND ITS FUNCTIONS IN FOODS:
As a food additive, E462 Ethyl cellulose plays a key role in ensuring the consistency, stability and quality of many food products.
Its versatile properties make E462 Ethyl cellulose a popular ingredient in the food industry, enabling manufacturers to create products with desirable organoleptic properties and a long shelf life.
PHYSICAL PROPERTIES of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose is typically a white to off-white powder or granules, odorless and tasteless.
E462 Ethyl cellulose is insoluble in water but soluble in organic solvents such as ethanol, toluene, and ethyl acetate.
Its hydrophobic nature allows E462 Ethyl cellulose to form films and coatings that provide barriers to moisture and gases.
E462 Ethyl cellulose also acts as a thickening agent in oil-based formulations.
INCI FUNCTIONS of E462 ETHYL CELLULOSE:
Binder agent.
E462 Ethyl cellulose that is used in cosmetic, food and pharmaceutical products as an anti-caking agent with the function of making the product in which it is incorporated silky, compact and homogenous.
The binder, either natural such as mucilage, gums and starches or chemical, may be in the form of a powder or liquid.
Film-forming agent.
E462 Ethyl cellulose produces, upon application, a very thin continuous film with an optimal balance of cohesion, adhesion and stickiness on skin, hair or nails to counteract or limit damage from external phenomena such as chemicals, UV rays and pollution.
Viscosity control agent.
E462 Ethyl cellulose controls and adapts, Increasing or decreasing, viscosity to the required level for optimal chemical and physical stability of the product and dosage in gels, suspensions, emulsions, solutions.
PROPERTIES of E462 ETHYL CELLULOSE:
E462 Ethyl cellulose has several important properties that make it an attractive food additive:
Thickening:
E462 Ethyl cellulose can be used to thicken a variety of foods, including sauces, mousses, jellies and other products, giving them the right texture.
Stabilization:
E462 Ethyl cellulose acts as a stabilizer, preventing the separation of ingredients in products such as sauces, mayonnaise and yogurts.
Gelling agent:
E462 Ethyl cellulose can be used to gel various substances, which is useful in the production of jellies, puddings and other products with a gel-like consistency.
PROPERTIES of E462 ETHYL CELLULOSE:
Appearance
E462 Ethyl cellulose is slightly hygroscopic white to off-white, odourless and tasteless powder.
Degree of Substitution (DS)
The average number of hydroxyl groups substituted per glucopyranose unit is known as the degree of substitution (DS).
The DS would be 3 if with a complete substitution.
It is required by the EU and the FDA, that for the food grade E462 E462 Ethyl cellulose, “the content of ethoxyl groups (-OC2H5) should not less than 44 % and not more than 50 % of on the dried basis, that’s equivalent to not more than 2.6 ethoxyl groups per anhydroglucose unit.”
Solubility
In water
Practically insoluble in water and E462 Ethyl cellulose is the only modified cellulose not soluble in water but soluble in ethanol.
In organic Solvents
E462 Ethyl cellulose is insoluble in glycerol and in propane-1,2-diol.
Its solubility in varying proportions in certain organic solvents depending upon the ethoxyl content:
Less than 46–48%: freely soluble in tetrahydrofuran, in methyl acetate, in chloroform and in aromatic hydrocarbon ethanol mixtures.
46–48% or more: freely soluble in ethanol, in methanol, in toluene, in chloroform and in ethyl acetate.
Viscosity
E462 Ethyl cellulose's viscosity depending on the concentration, temperature, degree of polymerization (DP), and the presence of salts or other additives.
Food
E462 Ethyl cellulose is suggested by China manufacturer, Shandong Head, that the viscosity (5% toluene ethanol solution, 25˚C) varies from 4-100 (mPa.s) when used in food and feed.
Pharma
The viscosity is advised from 4 to 300 (mPa.s) in pharmaceuticals applications such as for coating, release control, granulation, binding, micro-encapsulation.
HOW IS E462 ETHYL CELLULOSE MADE?
E462 Ethyl cellulose is a naturally occurring polymer produced from wood pulp or cotton by treatment with alkali and then ethylation of the alkali cellulose with ethyl chloride.
Following are the simple manufacturing process, details please see that of mE462 Ethyl cellulose, as both methods are very similar.
Step 1: Alkalinization
Cell-OH+NaOH →Cell•O-Na+ +H2O
Step 2: Etherification
Cell•O-Na+ +ClCH2CH3 →Cell-OCH2CH3 +NaCl
Different EC grade can be produced by controlling the substitution of ethoxyl groups.
PHYSICAL and CHEMICAL PROPERTIES of E462 ETHYL CELLULOSE:
Chemical Name: Ethyl Cellulose
Food Additive Number: E462
CAS Number: 9004-57-3
EC Number: 618-384-9
Molecular Formula: Variable polymer structure; commonly represented as [C6H7O2(OC2H5)3−x(OH)x]n
Molecular Weight: Variable depending on degree of polymerization and substitution
Chemical Class: Cellulose ether, modified polysaccharide
Appearance: White to off-white powder or granules
Odor: Odorless
Taste: Tasteless
Origin: Semi-synthetic cellulose derivative
Physical State: Solid powder or granular material
Appearance: White to slightly yellowish powder
Odor: Odorless
Taste: Tasteless
Chemical Nature: Non-ionic cellulose ether
Chemical Class: Hydrophobic cellulose derivative
Solubility in Water: Insoluble
Solubility in Organic Solvents: Soluble in ethanol, methanol, toluene, chloroform, ethyl acetate, and other organic solvents
Hydrophobicity: Strong hydrophobic and water-resistant behavior
Film-Forming Ability: Excellent film-forming properties
Thermoplastic Behavior: Thermoplastic polymer
Density: Approximately 1.07–1.18 g/cm³
Viscosity: Available in multiple viscosity grades
Thermal Stability: Good thermal stability under normal processing conditions
Melting Behavior: Softens gradually upon heating rather than showing a sharp melting point
Moisture Resistance: Excellent moisture barrier properties
Chemical Stability: Stable under normal storage conditions
pH Stability: Stable over a broad pH range
Mechanical Strength: Produces strong and flexible films
Transparency: Forms transparent coatings and films
Volatility: Non-volatile polymer
Hygroscopicity: Low hygroscopicity
Oxidation Resistance: Good resistance to oxidation
Light Stability: Good UV and light stability
Surface Activity: Limited surface-active behavior
Compatibility: Compatible with many resins, waxes, oils, and polymers
Biodegradability: Slowly biodegradable cellulose derivative
Electrical Properties: Good electrical insulating properties
Adhesion Properties: Good adhesive and binding capability
Barrier Properties: Effective oxygen and moisture barrier
Flexibility: Produces flexible and durable coatings
Hydrolysis Resistance: Resistant to hydrolysis under neutral conditions
Processing Performance: Easily processed into coatings and films
Combustibility: Combustible organic polymer
Shelf-Life Stability: Good long-term stability under dry storage conditions
Other(deleted CASRN): 11097-03-3
ECHA Reach Pre-Reg: 618-384-9
FDA UNII: 7Z8S9VYZ4B
MDL: MFCD00131037
XlogP3-AA: -1.50 (est)
CAS Number: 9004-57-3
EC Number: 618-384-9
Molecular Formula: Variable polymer structure; commonly represented as [C6H7O2(OC2H5)3−x(OH)x]n
Molecular Weight: Variable depending on degree of polymerization and substitution
~45,000 – 250,000 g/mol
Some industrial grades may exceed this range.
Appearance: white to tan powder (est)
Assay: 94.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in: water, 0.006149 mg/L @ 25 °C (est)
Insoluble in: water, glycerol
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Hygroscopic
CAS RN: 9004-57-3
PubChem Substance ID: 87569384
Merck Index (14): 3781
MDL Number: MFCD00131037
Physical state: powder
Color: beige
Odor: No data available
Melting point/freezing point: Melting point/range: 240 - 255 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity: Viscosity, kinematic: No data available
Viscosity, dynamic: 22 mPa.s at 20 °C
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,14 g/mL at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
FIRST AID MEASURES of E462 ETHYL CELLULOSE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of E462 ETHYL CELLULOSE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of E462 ETHYL CELLULOSE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of E462 ETHYL CELLULOSE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
HANDLING and STORAGE of E462 ETHYL CELLULOSE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of E462 ETHYL CELLULOSE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
