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E576 (SODIUM GLUCONATE)

E576 (Sodium Gluconate) can also be used as a stiffening agent for concrete.
E576 (Sodium Gluconate) can be used to prevent and treat sodium deficiency in the body.
E576 (Sodium Gluconate) can also be used as an additive to improve the digestibility of feed.


CAS Number: 527-07-1 
EC Number: 208-407-7
MDL Number: MFCD00064210
IUPAC Name: Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
IUPAC Name: Sodium 2,3,4,5,6-pentahydroxyhexanoate
E number: E576 (acidity regulators, ...)
Chemical formula: C6H11NaO7
Molecular Weight: 218.14 g/mol

SYNONYMS:
D-Gluconic acid sodium salt, Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, Gluconic acid, sodium salt, Sodium D-gluconate
E 576, Gluconic Acid Sodium Salt, Monosodium Gluconate, Sodium Fluconate, Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, Sodium D-gluconate, SODIUM GLUCONATE, 527-07-1, Sodium D-gluconate, D-Gluconic acid, monosodium salt, D-Gluconic acid sodium salt, Monosodium gluconate, gluconate sodium, Gluconic acid sodium salt, Glonsen, Monosodium D-gluconate, D-Gluconic acid, sodium salt, Gluconate (sodium), D-Gluconate sodium salt, D-Gluconic acid, sodium salt (1:1), Gluconic acid, monosodium salt, D-, Bvd addicrete, Clewat gl, Helshas a, Natrum gluconicum, sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, DTXSID7027170, CHEBI:84997, Sodium gluconate [USP], EINECS 238-976-7, MFCD00064210, 14906-97-9, D-Gluconic acid, sodium salt (1:?), R6Q3791S76, SODIUM GLUCONATE [II], SODIUM GLUCONATE [FCC], DTXCID007170, INS NO.576, sodium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, FEMA NO. 4934, SODIUM GLUCONATE [VANDF], SODIUM GLUCONATE [MART.], INS-576, GLUCONATE SODIUM [WHO-DD], 2,3,4,5,6-Pentahydroxycaproic acid sodium salt, SODIUM GLUCONATE [ORANGE BOOK], GLUCONIC ACID SODIUM SALT [MI], SODIUM GLUCONATE [USP MONOGRAPH], NCGC00164076-01, Sodium gluconate (USP), E-576, Gluconic acid, sodium salt, E-576-, NSC-759599, SODIUM GLUCONATE (II), C6H11NaO7, Pasexon 100T, SODIUM GLUCONATE (MART.), D-Gluconic acid sodium salt;Sodium D-gluconate;D-Gluconate sodium salt, SODIUM GLUCONATE (USP MONOGRAPH), Gluconato di sodio, Gluconato di sodio [Italian], EINECS 208-407-7, UNII-R6Q3791S76, Sodium Dgluconate, Monosodium Dgluconate, SCHEMBL23640, Sodium salt of D-gluconic acid, DGluconic acid, monosodium salt, SODIUM GLUCONATE [INCI], CHEMBL1200919, HY-B1092A, DTXSID00894961, Gluconic acid, monosodium salt, D, Tox21_112081, DGluconic acid, sodium salt (1:1), s4174, AKOS015899031, AKOS015951225, CCG-229938, CS-4777, NSC 759599, AS-11680, CAS-527-07-1, DA-57972, MG170849, G0041, NS00074302, D05862, Q264552, 208-407-7, 238-976-7, 692-539-9

E576 (Sodium Gluconate) is a white powder that is very soluble in water.
E576 (Sodium Gluconate) is a compound with formula NaC6H11O7.
E576 (Sodium Gluconate) is the sodium salt of gluconic acid.


E576 (Sodium Gluconate) is the sodium salt of gluconic acid, produced by fermentation of glucose.
E576 (Sodium Gluconate) is a white to tan, granular to fine, crystalline powder, very soluble in water.
E576 (Sodium Gluconate) is non-corrosive, non-toxic, and readily biodegradable (98% after 2 days), and is more and more appreciated as a chelating agent.


The outstanding property of E576 (Sodium Gluconate) is its excellent chelating power, especially in alkaline and concentrated alkaline solutions.
E576 (Sodium Gluconate) forms stable chelates with calcium, iron, copper, aluminium, and other heavy metals, and in this respect, it surpasses all other chelating agents, such as EDTA, NTA, and related compounds.


Aqueous solutions of E576 (Sodium Gluconate) are resistant to oxidation and reduction, even at high temperatures.
However, E576 (Sodium Gluconate) is easily degraded biologically (98% after 2 days), and thus presents no wastewater problem.
E576 (Sodium Gluconate) is also a highly efficient set retarder and a good plasticizer/water reducer for concrete, mortar, and gypsum.


E576 (Sodium Gluconate) has the property to inhibit bitterness in foodstuffs.
E576 (Sodium Gluconate) is a compound with formula NaC6H11O7.
E576 (Sodium Gluconate) is the sodium salt of gluconic acid.


E576 (Sodium Gluconate)'s E number is E576.
E576 (Sodium Gluconate) is a white powder that is very soluble in water.
E576 (Sodium Gluconate) is an organic compound that can be found in most of the products we consume every day.


E576 (Sodium Gluconate) is produced by the fermentation of sugar and takes the form of a white to pale yellow crystalline powder with a slightly salty taste.
E576 (Sodium Gluconate) is a salt of gluconic acid, which is naturally occurring in fruits such as berries or citrus fruits.


In humans, gluconic acid is found in the intestinal microflora.
E576 (Sodium Gluconate) is polyhydroxy sodium carboxylate.
E576 (Sodium Gluconate) is also called sodium pentahydroxy caproate.


E576 (Sodium Gluconate) molecular formula is C6H11O7Na.
E576 (Sodium Gluconate) molecular weight is 218.14.
E576 (Sodium Gluconate) is white or light yellow crystalline particles or powder in appearance, easily soluble in water, slightly soluble in alcohol, and insoluble in ether.


E576 (Sodium Gluconate) is an organic sodium salt having D-gluconate as the counterion.
E576 (Sodium Gluconate) has a role as a chelator.
E576 (Sodium Gluconate) contains a D-gluconate.


E576 (Sodium Gluconate) is the sodium salt of gluconic acid with chelating property.
E576 (Sodium Gluconate) chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
E576 (Sodium Gluconate) F.C.C. is a high-quality crystalline sodium salt of gluconic acid.


E576 (Sodium Gluconate) appears as white crystals that exhibit excellent solubility.
This non-corrosive, non-toxic and highly pure gluconate, E576 (Sodium Gluconate), is an excellent choice when dry material is preferred.
Bulk density of E576 (Sodium Gluconate) is approximately 59 pounds per cubic foot (.95 g/cc).


E576 (Sodium Gluconate) is an excellent chelating agent, especially in alkaline and concentrated alkaline solutions.
Aqueous solutions of E576 (Sodium Gluconate) are resistant to oxidation and reduction, even at high temperatures while being biodegradable.
E576 (Sodium Gluconate) is also a highly efficient set retarder and a good plasticizer/water reducer for concrete, mortar, and gypsum.


E576 (Sodium Gluconate) is the sodium salt of gluconic acid, produced by fermentation of glucose.
E576 (Sodium Gluconate) is a white, granular to fine, crystalline powder, very soluble in water.
Non-corrosive, non-toxic and readily biodegradable (98% after 2 days),


E576 (Sodium Gluconate) is more and more appreciated as a chelating agent.
E576 (Sodium Gluconate) has a non-irritating, non-bitter, non-sour, slightly salty taste.
The outstanding property of E576 (Sodium Gluconate) is its excellent chelating power.


E576 (Sodium Gluconate) forms stable chelates with calcium, iron, copper, aluminium, and other heavy metals,
and surpasses all other chelating agents, such as EDTA, NTA and related compounds.
Aqueous solutions of E576 (Sodium Gluconate) are resistant to oxidation and reduction,
even at high temperatures.


And last but not least, E576 (Sodium Gluconate) has the property to inhibit bitterness in foodstuffs.
E576 (Sodium Gluconate) is a mix with gluconic acid (from GDL) forms a buffer of pH of 3.65 to 3.80.
E576 (Sodium Gluconate) is the sodium salt of gluconic acid, E574. E576 (Sodium Gluconate) is a synthetic. 


E576 (Sodium Gluconate) picks up metal traces and holds them in the product in a form of chelation.
E576 (Sodium Gluconate) is a white solid substance
E576 (Sodium Gluconate) is an organic sodium salt having D-gluconate as the counterion.


E576 (Sodium Gluconate) has a role as a chelator.
E576 (Sodium Gluconate) is a white powder that is very soluble in water.
E576 (Sodium Gluconate) is a compound with formula NaC6H11O7.


E576 (Sodium Gluconate) is the sodium salt of gluconic acid.
E576 (Sodium Gluconate) (E576), chemically known as C6H11NaO7, is a prominent food-grade additive derived from gluconic acid.
E576 (Sodium Gluconate) is extensively used in the food industry as a preservative, stabilizer, and chelating agent.


E576 (Sodium Gluconate)’s ability to bind with metals and minerals makes it an essential ingredient in various food processing applications.
This introduction will explore the fundamental aspects of E576 (Sodium Gluconate), underscoring its critical contributions to food safety and quality enhancement.


E576 (Sodium Gluconate) is a compound with the formula NaC6H11O7.
E576 (Sodium Gluconate) is the sodium salt of gluconic acid. 
E576 (Sodium Gluconate) is produced by fermentation of glucose and non-treatment of the resulting gluconic acid with sodium hydroxide.


E576 (Sodium Gluconate) is non-toxic, non-corrosive, highly water soluble and rapidly biodegradable (98% in 2 days).
E576 (Sodium Gluconate) is soluble in water.
Sodium gluconate or E576 (Sodium Gluconate), the sodium salt of gluconic acid with the European food additive number E576 (Sodium Gluconate), is different from other gluconates that can be used as a nutrient.


E576 (Sodium Gluconate) is a compound with formula NaC6H11O7.
E576 (Sodium Gluconate) is the sodium salt of gluconic acid.
Its E number is E576 (Sodium Gluconate).


This white, water-soluble powder, E576 (Sodium Gluconate), has a wide range of applications across industries.
Sodium gluconate, designated as E576 (Sodium Gluconate), is the sodium salt of gluconic acid, with the chemical formula C₆H₁₁NaO₇.
E576 (Sodium Gluconate) is a white, crystalline powder known for its excellent chelating properties, making E576 (Sodium Gluconate) valuable across various industries.


E576 (Sodium Gluconate) is a white to tan, granular to fine, practically odorless crystalline powder that is highly soluble in water.
E576 (Sodium Gluconate) is the sodium salt of gluconic acid, produced by fermentation of glucose.
E576 (Sodium Gluconate) is a white to tan, granular to fine, crystalline powder, very soluble in water.


Non-corrosive, non-toxic and readily biodegradable (98 % after 2 days), E576 (Sodium Gluconate) is more and more appreciated as a chelating agent.
The outstanding property of E576 (Sodium Gluconate) is its excellent chelating power, especially in alkaline and concentrated alkaline solutions.


E576 (Sodium Gluconate) forms stable chelates with calcium, iron, copper, aluminium, and other heavy metals, and in this respect, E576 (Sodium Gluconate) surpasses all other chelating agents, such as EDTA, NTA, and related compounds.
Aqueous solutions of E576 (Sodium Gluconate) are resistant to oxidation and reduction, even at high temperatures.


However, E576 (Sodium Gluconate) is easily degraded biologically (98 % after 2 days), and thus presents no wastewater problem.
E576 (Sodium Gluconate) is also a highly efficient set retarder and a good plasticiser/water reducer for concrete, mortar, and gypsum.
And last but not least, E576 (Sodium Gluconate) has the property to inhibit bitterness in foodstuffs.

USES and APPLICATIONS of E576 (SODIUM GLUCONATE):
E576 (Sodium Gluconate)'s early uses were primarily in medicine due to its mild and non-toxic properties.
Over time, E576 (Sodium Gluconate)'s applications expanded to various industries, including food, pharmaceuticals, construction, textiles, and more, as its versatile properties and safety profile became more widely recognized.


Food Industry: E576 (Sodium Gluconate) is used as a food additive for various purposes, including as a sequestrant to prevent metal ions from affecting the color, flavor, or stability of food products.
Textiles: In textile dyeing and printing, E576 (Sodium Gluconate) is utilized as a chelating agent to improve color fastness.


Metallurgy: E576 (Sodium Gluconate) is employed for metal surface treatment and cleaning, particularly for steel surfaces.
Cleaning Products: E576 (Sodium Gluconate) can be found in cleaning agents for glass bottles and as a chelating agent in various cleaning formulations.


Applications of E576 (Sodium Gluconate): Food, Baby food | Infant formula, Cereals | Snacks, Confectionery, Dairy alternatives, Flavours, and Fruits | Vegetables.
E576 (Sodium Gluconate) is used Meat | Seafood, Meat alternatives, Ready meals | Instant food, Sauces | Dressings | Seasonings, Table top products, A bowl filled with salad containing chicken, and More about Food.


E576 (Sodium Gluconate) is used Beverages, Carbonated soft drinks, Plant-based, Sports drinks | Energy drinks, Tea | Coffee | RTD, and Waters.
E576 (Sodium Gluconate) is a multi-functional ingredient that can be used in a lot of fields, commonly used for its outstanding chelating property in food and industrial uses.


E576 (Sodium Gluconate) is also used for its PH buffering and taste improvement in food.
In construction, E576 (Sodium Gluconate) is used as a water reducer and inhibitor in the construction industry.
E576 (Sodium Gluconate) is an effective inhibitor and a good plasticizer and water reducer for concrete, cement, mortar and gypsum.


E576 (Sodium Gluconate) can also be used as a stiffening agent for concrete.
E576 (Sodium Gluconate) can significantly delay the onset of curing and the end of setting of concrete, which is an important advantage in difficult conditions such as long transport times, hot summer days or tropical weather.


In addition to its widespread use as a very effective bond retarder, E576 (Sodium Gluconate) also acts as a water reducer and provides better workability of concrete mixes.
In heating systems, E576 (Sodium Gluconate) is used as a water quality stabilizer as it is an excellent inhibitor of sedimentation, a water softener and an anti-corrosive additive to prevent metal decomposition in the heating system.


In medicine, E576 (Sodium Gluconate) can maintain the acid-base balance in the human body and restore normal nerve function.
It can be used to prevent and treat sodium deficiency in the body.
In animal husbandry, E576 (Sodium Gluconate) can be used to improve the uptake of iron, calcium, magnesium, aluminum and other metals from feed.


E576 (Sodium Gluconate) can also maintain the acid-base balance in the animal's body and restore normal nerve function.
E576 (Sodium Gluconate) can be used to prevent and treat sodium deficiency in the body.
E576 (Sodium Gluconate) can also be used as an additive to improve the digestibility of feed.


In the food industry, E576 (Sodium Gluconate) acts as a stabilizer, sequestrant and thickener when used as a food additive (E576).
Compared to the intense taste of standard acids and their salts, such as citric, malic and lactic acid, gluconic acid has a slightly sweet, mildly acidic taste and a persistent tongue action.


E576 (Sodium Gluconate) reduces the bitterness of high-intensity sweeteners (HIS) such as stevia, minerals and caffeine.
E576 (Sodium Gluconate) masks the side notes or aftertastes of vegetable proteins and artificial high-intensity sweeteners such as saccharin and aspartame, making them suitable for widespread use in low- to medium-calorie non-alcoholic, sports or energy drinks.


The unique properties of E576 (Sodium Gluconate) make it an excellent choice for healthier and better tasting drinks.
E576 (Sodium Gluconate) is also approved by FEMA as a flavor ingredient with modifying properties and can be labelled as a natural flavoring if the conditions for declaration are met.


E576 (Sodium Gluconate) has FEMA No 4934.
E576 (Sodium Gluconate) also acts as a stabilizer in meat products, in particular in emulsion-type sausages such as frankfurters.
E576 (Sodium Gluconate) increases the ionic strength and causes the muscle proteins to swell and unfold.


This increases the water-binding capacity, which has a positive effect on the firmness and cutting properties of the meat.
In cosmetics, E576 (Sodium Gluconate) is used as a product stabilizer to prevent discoloration and the degradation of fats (which, when degraded, give off an unpleasant odor due to the release of saturated acids).


E576 (Sodium Gluconate) is commonly used in cosmetic oils and butter-type products.
E576 (Sodium Gluconate) also acts as a humectant and pH regulator.
E576 (Sodium Gluconate) is used as a natural alternative to synthetic chelates (metal ion binders) such as EDTA, NTA, etc.


E576 (Sodium Gluconate) is commonly used in concentrations of 0.1-1.0%.
E576 (Sodium Gluconate) is used for external use only.
E576 (Sodium Gluconate) can be used in all types of products: creams, lotions, shampoos, conditioners, make-up or tanning products.


E576 (Sodium Gluconate) is used as a chelating agent, forming complexes with metal ions which may affect the stability and appearance of cosmetic products.
Gluconates are added to cleansers and shampoos to increase foaming by breaking down hard water ions.


Gluconates are also used in oral and dental care products such as toothpaste, where E576 (Sodium Gluconate) is used to sequester calcium and help prevent gingivitis.
Healthcare uses of E576 (Sodium Gluconate): OTC | Food supplements.


E576 (Sodium Gluconate) is used Personal Care, Colour cosmetics, Hair care, Oral care, Skin care, Soap | Bath products, Cleaners & Detergents, Dish washing, Industrial cleaners, Laundry care, and Surface care.
Industrial Applications of E576 (Sodium Gluconate): Agrochemicals | Fertilisers, Construction, Fine chemicals, Inks | Paints | Coatings, Metal surface treatment, Paper, Textile | Leather, Three paint tubes with green, yellow and red paint.


E576 (Sodium Gluconate) is used Feed & Pet Food, Feed, and Pet Food.
E576 (Sodium Gluconate) is used Pharma, Bitterness masking agent, Buffering agent, and Chelating agent.
E576 (Sodium Gluconate) is used Chelating agent in foods, cleaning applications, electroplating, concrete admixtures


Recommended Use of E576 (Sodium Gluconate): Acid Cleaners, Aluminum Deoxidizer, Aluminum Etchant, Bar Soap, Body Wash, Bottle Washing, Chelating Agent, Concrete Admixtures, Concrete Set Time Retarder, Conditioners, Deicer, Detergents, Dishwash Detergents, Dyes, Electroplating, Facial Cleaner, Food Processing Cleaners, Hair Care, Hair Conditioner, and Hair Removal.


E576 (Sodium Gluconate) is used Creams & Lotions, Hand Soap, Liquid Hand Soap, Lithography, Metal Cleaners, Moisturizing Cream Formulations, Mordant - Dyes, Oil Well Cementing, Oil Well Cementing Set Time Retarder, Paint Strippers, Pharmaceuticals, Printing, Pulp & Paper, Rust Removers, Sequesterant, Shampoo, Shower Gels, Skin Care Products, Textile, and Toothpaste.


In metalworking, E576 (Sodium Gluconate) is used as a particularly effective remover of iron deposits (both iron oxides and iron sulfides, etc. salts).
E576 (Sodium Gluconate) itself is not aggressive and therefore does not corrode metals, but due to its highly effective chelating effect it quickly binds metal ions, thus gently cleaning the metal surface.


E576 (Sodium Gluconate) is stable both at high temperatures and in alkaline and highly concentrated alkaline solutions, forming stable chelates, making it more effective than EDTA, NTA and other similar chelates.
E576 (Sodium Gluconate) is often used in the food industry as a preservative and stabilizer.


E576 (Sodium Gluconate) is added to foods as a salt to improve taste and extend shelf life.
E576 (Sodium Gluconate) is also used in the cosmetics industry as a humectant, i.e. a substance that prevents cosmetic products from drying out.
E576 (Sodium Gluconate) is also an active ingredient in various cleaning products.


E576 (Sodium Gluconate) is a safe substance that has been assessed by the European Food Safety Authority (EFSA) as harmless to human health.
Nevertheless, care must be taken to consume E576 (Sodium Gluconate) in reasonable quantities, as is the case with all other additives.
E576 (Sodium Gluconate) is widely used in textile dyeing, printing, and metal surface water treatment.


E576 (Sodium Gluconate) is also used as a chelating agent, a steel surface cleaning agent, a cleaning agent for glass bottles, and as a chelating agent for cement, plating, and alumina dyeing industries.
E576 (Sodium Gluconate) is widely used in textile dyeing, printing, and metal surface water treatment.


Application of E576 (Sodium Gluconate): As steel surface cleaning agent, As cement admixture, Used in electroplating, film industry, Widely used in the construction industry (as water reducing agent or cement setting retarder), As special cleaning agent for glass bottles, As water quality stabilizer and softener, and Food additive.


Other Uses of E576 (Sodium Gluconate): Metal cleaner, paint stripper, metal plating, rust remover.
E576 (Sodium Gluconate) is also used as a chelating agent, a steel surface cleaning agent, a cleaning agent for glass bottles, and as a chelating agent for cement, plating, and alumina dyeing industries.


E576 (Sodium Gluconate) is used as a Raw material for the metallurgical industry, Raw material for the food industry, Raw material for construction chemicals, Raw material for household chemicals production, Raw material for adhesives, oils, and lubricants production,
Raw material for fertilizer production, and Raw material for plastics production.


Usage of E576 (Sodium Gluconate): Water Treatment Chemicals, Plastic Auxiliary Agents, Coating Auxiliary Agents, Paper Chemicals, Leather Auxiliary Agents, Electronics Chemicals
Uses: E576 (Sodium Gluconate) is found in baked goods, confectionary, soft, sports and fizzy drinks, processed meats, nutritional supplements, desserts.


E576 (Sodium Gluconate) is widely used in textile dyeing, printing and metal surface water treatment.
Originally derived from gluconic acid in the 19th century, E576 (Sodium Gluconate) is known for its chelating properties and is utilized as a chelating agent in various processes.


E576 (Sodium Gluconate) finds applications in textile, metal surface treatment, cement, and more.
Moreover, E576 (Sodium Gluconate)'s non-toxic nature and biodegradability contribute to its use in environmentally conscious practices.
E576 (Sodium Gluconate) is mainly used as a chelating agent and cleaner in food and industrial uses.


Cosmetics: E576 (Sodium Gluconate) functions as a chelating and skin conditioning in cosmetic and personal care products. 
And usually we can find it in skin care products like face cream, soap, and toothpaste.
E576 (Sodium Gluconate) is used industrial uses and Chelating agent


E576 (Sodium Gluconate) is with good sequestering power (over EDTA, NTA, and some other related compounds) to combine with di- and trivalent metal ions, such as calcium, iron, copper, aluminium to form stable chelates and take them out of water or the solution at an alkaline pH, and with little effect on temperature.


Due to this property, E576 (Sodium Gluconate) is widely used in: Water treatment, Bottle washing, Corrosion inhibition, Metal surface treatment, Industrial cleaning, and Concrete retarder.
In addition, E576 (Sodium Gluconate) can be used in the construction industry, as a retarding cement enhancing additive.


E576 (Sodium Gluconate) is classified into “Group I” with the maximum use levels “quantum satis”, which means there is no specific limit in its uses.
Chelating Agent: E576 (Sodium Gluconate) is effectively binds metal ions, preventing unwanted reactions in industrial processes.


The following food may contain E576 (Sodium Gluconate): Dairy products, Fats and oils and fat and oil emulsions, Fruit and vegetables, Confectionery, Cereals and cereal products, Bakery wares, Meat, Fish and fisheries products, Eggs and egg products, Table-top sweeteners, Salts, spices, soups, sauces, salads, and protein products, and Beverages.


Construction Industry: E576 (Sodium Gluconate) serves as a concrete admixture to enhance workability and retard setting time.
Textile Industry: E576 (Sodium Gluconate) is utilized in dyeing and printing to improve color consistency and prevent metal ion interference.
Food Industry: Employed as a food additive (E576 (Sodium Gluconate)) to control acidity and improve the stability of food products.


Personal Care Products: E576 (Sodium Gluconate) acts as a chelating agent in cosmetics and personal care items to enhance product stability.
Food Industry: Utilized as a food additive (E576 (Sodium Gluconate)) functioning as a sequestrant to prevent metal ions from affecting the color, flavor, or stability of food products.


Construction: E576 (Sodium Gluconate) is employed as a concrete admixture to act as a water reducer and retarder, enhancing the workability and performance of concrete.
Textile Industry: E576 (Sodium Gluconate) is used as a chelating agent in textile dyeing and printing to improve color fastness.


Personal Care Products: E576 (Sodium Gluconate) serves as a chelating agent and skin-conditioning agent in products like soaps, shampoos, and cosmetics.
Cleaning Agents: E576 (Sodium Gluconate) functions as a chelating agent in various cleaning formulations, including glass and bottle cleaning.


Medicine: E576 (Sodium Gluconate) acts as a biologically neutral carrier of minerals such as calcium, iron, and potassium in pharmaceutical applications.
Chelating Agent: E576 (Sodium Gluconate) is effectively binds metal ions, preventing unwanted reactions in industrial processes.


-Food uses of E576 (Sodium Gluconate):
Food grade E576 (Sodium Gluconate) can be used as:
*A sequestrant agent by chelating undesirable metal ions.
*A PH buffer in drink.
*A taste improver for beverage by masking off-notes or reducing the bitterness/aftertaste from artificial sweeteners, soybean protein, minerals or caffeine.
*A stabilizer in meat products by increasing meat water-binding capacity and improving its firmness and sliceability.
Meanwhile, E576 (Sodium Gluconate) is a replacement of phosphates. 


-Pharma & Nutraceutical uses of E576 (Sodium Gluconate):
E576 (Sodium Gluconate) can be used as an excipient as a buffer and pH adjuster in the following products:
*Syrups
*Suspension
*Swallowable/orally dispersible tablets
*Hard capsules


-Construction uses of E576 (Sodium Gluconate):
E576 (Sodium Gluconate) is employed in the construction industry as a concrete admixture.
E576 (Sodium Gluconate) acts as a water reducer and retarder, enhancing the workability and performance of concrete.


-Applications in the Food Industry
E576 (Sodium Gluconate) is a versatile additive in the food industry, utilized for its excellent chelating and stabilizing properties.
This section discusses its broad range of applications, detailing how E576 (Sodium Gluconate) enhances food products’ safety, shelf-life, and quality.


-As a Food Additive: Purposes and Benefits
E576 (Sodium Gluconate) is primarily used as a sequestrant, a substance that binds and removes metal ions, which can catalyze oxidative spoilage in food products.

E576 (Sodium Gluconate) helps to improve the texture and stability of foods, prevents discoloration, and extends shelf life, making it invaluable in packaged and canned foods.


-Specific Uses in Different Food Products
In dairy products, E576 (Sodium Gluconate) prevents milk proteins from precipitating and keeps essential minerals soluble, enhancing the smoothness of dairy desserts and creams.

In baked goods, E576 (Sodium Gluconate) regulates the pH level and acts as a leavening agent.
In meat processing, E576 (Sodium Gluconate) helps in curing and seasoning by stabilizing color and flavor.


-Regulatory Status and Typical Concentrations Used
Major health authorities, such as the FDA and EFSA, deem E576 (Sodium Gluconate) as safe for use.
E576 (Sodium Gluconate) is used in concentrations typically ranging from 0.1% to 0.3% by weight of the final product, depending on the specific application and local regulatory guidelines.

E576 (Sodium Gluconate) or sodium d-gluconate, the sodium salt of gluconic acid with the European food additive number E576, is different from other gluconates that can be used as a nutrient.
E576 (Sodium Gluconate) is mainly used as a chelating agent and cleaner in food and industrial uses.

APPLICATIONS AND MAIN FUNCTIONS OF E576 (SODIUM GLUCONATE):
Applications & Main functions
*Excellent chelating agent
*Efficient plasticiser / water reducer
*Efficient set retarder
*Bitterness inhibitor

CHEMICAL PROPERTIES OF E576 (SODIUM GLUCONATE):
E576 (Sodium Gluconate), with its chemical formula C6H11NaO7, exhibits unique characteristics that make it valuable in the food industry.
This section outlines E576 (Sodium Gluconate)'s fundamental physical and chemical attributes, stability, and reactivity, which are crucial for its applications.

CHEMICAL FORMULA AND STRUCTURE OF E576 (SODIUM GLUCONATE):
E576 (Sodium Gluconate) is the sodium salt derivative of gluconic acid.
E576 (Sodium Gluconate) usually appears as a granular to fine crystalline powder, ranging in color from white to tan.
E576 (Sodium Gluconate) dissolves easily in water, creating a clear and colorless solution.

KEY PHYSICAL AND CHEMICAL CHARACTERISTICS OF E576 (SODIUM GLUCONATE):
E576 (Sodium Gluconate) is non-toxic, biodegradable, and has excellent chelating properties, making it effective at binding calcium, iron, and other metals which can be beneficial in preventing oxidation and spoilage in food products.

STABILITY AND REACTIVITY OF E576 (SODIUM GLUCONATE) UNDER VARIOUS CONDITIONS:
E576 (Sodium Gluconate) is stable under ordinary conditions of use and storage.
E576 (Sodium Gluconate) does not decompose under high temperatures used in food processing and is non-reactive with other food ingredients.
E576 (Sodium Gluconate) stability in acidic and alkaline environments also contributes to its versatility as a food additive.

MAIN INCI FUNCTIONS OF E576 (SODIUM GLUCONATE):
*Chelate: 
E576 (Sodium Gluconate) reacts and forms complexes with metal ions which can affect the stability and/or appearance of cosmetic products.

*Skin conditioning: 
E576 (Sodium Gluconate) maintains good skin condition

KEY RAW MATERIALS USED IN THE PRODUCTION OF E576 (SODIUM GLUCONATE):
The primary raw material for producing E576 (Sodium Gluconate) is glucose, which can be derived from various starch-rich sources like corn, rice, or wheat.
The process also requires sodium hydroxide for neutralization and specific microbes for the fermentation stage.

INNOVATIONS IN PRODUCTION TECHNOLOGY OF E576 (SODIUM GLUCONATE):
Recent innovations in the production of E576 (Sodium Gluconate) focus on improving the fermentation yields and reducing energy consumption.
Techniques such as continuous fermentation, the use of genetically modified organisms for higher efficiency, and optimization of the microbial environment are significant advancements that have improved the sustainability and cost-effectiveness of production.

PRODUCTION PROCESS OF E576 (SODIUM GLUCONATE):
The industrial production of E576 (Sodium Gluconate) involves several key steps, utilizing specific raw materials and incorporating modern technological advancements to enhance efficiency and output.
This segment outlines the production process, highlighting how E576 (Sodium Gluconate) is manufactured.

HOW E576 (SODIUM GLUCONATE) IS PRODUCED INDUSTRIALLY:
E576 (Sodium Gluconate) is typically produced via the fermentation of glucose.
In this process, a particular strain of bacteria is employed to transform glucose into gluconic acid.

This acid is subsequently neutralized using sodium hydroxide to create E576 (Sodium Gluconate).
This technique is favored for E576 (Sodium Gluconate)'s high efficiency and the exceptional quality of the product it yields.

BENEFITS OF E576 (SODIUM GLUCONATE):
*Non-Toxic and Biodegradable: 
Environmentally friendly profile allows for safe use in various applications.

*Effective at Alkaline pH: 
E576 (Sodium Gluconate) maintains chelating efficacy in high pH environments, outperforming some other chelating agents.

*Enhances Product Stability: 
E576 (Sodium Gluconate) prevents degradation caused by metal ions in formulations.

PROPEERTIES OF E576 (SODIUM GLUCONATE):
*Non-toxic
*Easily biodegradable (98% after 2 days)

MAIN FUNCTIONS OF E576 (SODIUM GLUCONATE):
*Excellent chelating agent
*Highly efficient set retarder
*Efficient plasticiser/water reducer
*Bitterness inhibitor

BENEFITS AND CHARACTERISTICS OF E576 (SODIUM GLUCONATE):
Chelating Properties: 
Effectively forms stable complexes with various metal ions, preventing undesirable reactions.

Biodegradability: 
Readily biodegradable, making it environmentally friendly.

Non-Toxicity: 
Considered non-toxic and safe for use in food and pharmaceutical applications.

Stability: 
E576 (Sodium Gluconate) exhibits stability under standard conditions, with a melting point of 205–209 °C.

PRODUCTION OF E576 (SODIUM GLUCONATE):
E576 (Sodium Gluconate) can be produced through the fermentation process or chemical synthesis.
In the fermentation process, glucose is fermented by certain microorganisms, typically strains of Aspergillus niger or Pseudomonas.
Gluconic acid is the primary product of this fermentation, and E576 (Sodium Gluconate) is derived by neutralizing gluconic acid with sodium hydroxide.

SOURCE OF E576 (SODIUM GLUCONATE):
The production of E576 (Sodium Gluconate) commences with its precursor, gluconic acid.
This organic acid, E576 (Sodium Gluconate), is often obtained through a fermentation process.
Glucose, or other sugar sources, serves as the substrate for microorganisms, typically bacteria or fungi, to produce gluconic acid.

CONVERSION TO E576 (SODIUM GLUCONATE):
Once gluconic acid is harvested, it undergoes a transformation into E576 (Sodium Gluconate).
The conversion primarily involves a chemical reaction where gluconic acid is neutralized with sodium hydroxide (NaOH).
This reaction results in the formation of E576 (Sodium Gluconate), where the sodium ions (Na+) replace the hydrogen ions (H+) in gluconic acid.

PURIFICATION AND CRYSTALLIZATION OF E576 (SODIUM GLUCONATE):
Purification often includes filtration and chemical treatments to achieve the desired level of purity.
Following purification, the solution is subjected to crystallization.

DRYING AND PACKAGING OF E576 (SODIUM GLUCONATE):
After crystallization, the E576 (Sodium Gluconate) crystals still contain residual moisture.
Drying may involve processes like air drying or spray drying.

STRUCTURE OF E576 (SODIUM GLUCONATE):
E576 (Sodium Gluconate) chemical structure;
There are five hydroxyl groups and a carboxylic acid group in the chemical structure.

PROPERTIES OF E576 (SODIUM GLUCONATE):
Appearance
E576 (Sodium Gluconate) is a white to tan powder or granular.

Solubility
E576 (Sodium Gluconate) is very soluble in water, sparingly soluble in ethanol.

PH
Between 6.5 and 7.5 (10 % solution) 

IS E576 (SODIUM GLUCONATE) SAFE TO EAT?
Yes, E576 (Sodium Gluconate) has been approved safe by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

FDA
E576 (Sodium Gluconate) is generally recognized as safe (GRAS) when used as a sequestrant in food. 

EFSA
E576 (Sodium Gluconate) (E576) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “additives other than colours and sweeteners”.

PHYSICAL and CHEMICAL PROPERTIES of E576 (SODIUM GLUCONATE):
IUPAC Name: Sodium 2,3,4,5,6-pentahydroxyhexanoate
Common Name: Sodium Gluconate
CAS Number: 527-07-1
EC Number: 208-407-7
E Number: E576
MDL Number: MFCD00064210
HS Code: 2918 16 00
Molecular Formula: C₆H₁₁NaO₇
Empirical Formula (Hill Notation): C6H11NaO7
Molecular Weight: 218.14 g/mol

Appearance: White to light beige crystalline powder 
/ White or almost white, fine crystalline powder
Odor: Practically odorless
Odorless
Physical State: Solid, powder
Density: 1.79 g/cm³ at 20 °C
Melting Point: 205–209 °C
Boiling Point: Decomposes at 196–198 °C
Initial boiling point (calculated): 613.1 °C
Flash Point: Not applicable

Autoignition Temperature: >200 °C
Decomposition Temperature: 196–198 °C
Solubility in Water: Very soluble (590 g/L at 25 °C or 58 g/100 mL)
Solubility in Ethanol: Sparingly/slightly soluble
Solubility in Diethyl Ether: Practically insoluble
pH (100 g/L in water at 20 °C): 6.5–7.5 / 7.0–8.0
Partition Coefficient (log Pow): −5.99 → Very low bioaccumulation potential
Vapor Pressure: <0.1 hPa at 25 °C
Viscosity: No data available
[α]D²⁰: +11° to +13° (c = 10, H₂O)

Explosive Properties: Not classified as explosive
Oxidizing Properties: None
Ignition Temperature: >200 °C
Flash Point: Not applicable
Residual Solvents: Excluded by manufacturing process (per ICH Q3C)
Chloride (Cl): ≤ 0.04%
Sulfate (SO₄): ≤ 0.02%
Lead (Pb): ≤ 1 ppm
Reducing Substances: ≤ 0.5%
Assay (Perchloric Acid Titration): 99.0–102.0%
Identity (Wet Chemistry & TLC): Passing test

Molecular Weight: 218.14 g/mol
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 5
Exact Mass: 218.04024697 Da
Monoisotopic Mass: 218.04024697 Da
Topological Polar Surface Area: 141 Ų
Heavy Atom Count: 14
Formal Charge: 0

Complexity: 176
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 4
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
CAS number: 527-07-1
EC number: 208-407-7
Grade: And 576

Hill Formula: C₆H₁₁NaO₇
Molar Mass: 218.14 g/mol
HS Code: 2918 16 90
Density: 1.79 g/cm3 (20 °C)
Ignition temperature: >200 °C
Melting Point: 205 - 209 °C
pH value: 6.5 - 7.5 (H₂O)
Vapor pressure: <0.1 hPa (25 °C)
Solubility: 590 g/l

FIRST AID MEASURES of E576 (SODIUM GLUCONATE):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of E576 (SODIUM GLUCONATE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of E576 (SODIUM GLUCONATE):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of E576 (SODIUM GLUCONATE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of E576 (SODIUM GLUCONATE):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of E576 (SODIUM GLUCONATE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
 

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