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E952 (Cyclamic acid)


CAS NO:100-88-9
EC NO:202-898-1

E952 (Cyclamic acid) is a compound with formula C6H13NO3S.

E952 (Cyclamic acid) is included in E number "E952".

E952 (Cyclamic acid) is mainly used as catalyst in the production of paints and plastics, and furthermore as a reagent for laboratory usage.

The sodium and calcium salts of E952 (Cyclamic acid) are used as artificial sweeteners under the name cyclamate.

Properties:
Chemical formula:C6H13NO3S
Molar mass:179.23 g·mol−1

Salts and esters of E952 (Cyclamic acid).
E952 (Cyclamic acid) is a member of the class of sulfamic acids that is sulfamic acid carrying an N-cyclohexyl substituent. 
E952 (Cyclamic acid) has a role as a human xenobiotic metabolite and an environmental contaminant. 
E952 (Cyclamic acid) derives from a sulfamic acid. 
E952 (Cyclamic acid) is a conjugate acid of a cyclohexylsulfamate.

Use of E952 (Cyclamic acid):
*Non-nutritive sweetener
*Acidulant
*Sodium and calcium cyclamates are used as non-nutritive sweeteners ... Calcium cyclamate is used in low-sodium and sodium-free products
*CHEM INT FOR SALTS (NONCALORIC SWEETENERS)
*The main application of cyclamates ... is in blends with saccharin in a 10:1 ratio by weight. In these blends, quantitative and qualitative synergistic effects can be used to advantage, rendering them an important sweetener system in countries approving the use of both sweeteners.

Calorie-free sweetener for food, pharmaceutical and technical use. Sweetening power about 40 times higher than sucrose. Highly stable, good shelf-life, tooth-friendly and suitable for people with diabetes. Very synergistic with other low-calorie sweeteners.

Although permitted as sweetener for food, E952 (Cyclamic acid) is mainly used in applications as production of paint, resins, polymeric coating and urethane.

E952 (Cyclamic acid) (Cyclamate) is banned in the United States but it is used in many other Western countries without safety concerns. 

E952 (Cyclamic acid) (NSC 220327) in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.
    
E952 (Cyclamic acid) in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners in food and pharmaceuticals. 
E952 (Cyclamic acid) is in use in more than 50 countries, especially in combination with other sweeteners, to eliminate aftertaste.

E952 (Cyclamic acid), also known as cyclamate or hexamic acid, belongs to the class of organic compounds known as cyclamates. 
Cyclamates are compounds containing a cyclohexylsulfamic acid moiety. 
E952 (Cyclamic acid) is a primary metabolite. Primary metabolites are metabolically or physiologically essential metabolites. They are directly involved in an organism’s growth, development or reproduction. Based on a literature review a significant number of articles have been published on E952 (Cyclamic acid).

E952 (Cyclamic acid) (Cyclohexylsulfamic acid) sodium is one of the most widely used artificial sweetenersin food and pharmaceuticals.

E952 (Cyclamic acid) is one of the most widely used artificial sweeteners.
E952 (Cyclamic acid) is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogenic activity (disputed).

E952 (Cyclamic acid) in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.

E952 (Cyclamic acid) is a useful biochemical reagent that is commonly used as catalyst in the production of paints and plastics.

E952 (Cyclamic acid) is a white crystalline solid, C6H13NSO3, the salts of which are referred to as cyclamates: used as an acidulant.

E952 (Cyclamic acid) uses and applications include: Nonnutritive sweetener, acidulant in foods

FUNCTIONS:
-Acidulant
-Acid 

About E952 (Cyclamic acid)
Helpful information
E952 (Cyclamic acid) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.

E952 (Cyclamic acid) is used in manufacturing.

Consumer Uses
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which E952 (Cyclamic acid) is most likely to be released to the environment.

Article service life
ECHA has no public registered data on the routes by which E952 (Cyclamic acid) is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using E952 (Cyclamic acid). ECHA has no public registered data on the routes by which E952 (Cyclamic acid) is most likely to be released to the environment.

Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which E952 (Cyclamic acid) is most likely to be released to the environment.

Uses at industrial sites
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using E952 (Cyclamic acid). ECHA has no public registered data on the routes by which E952 (Cyclamic acid) is most likely to be released to the environment.

Manufacture
ECHA has no public registered data on the routes by which E952 (Cyclamic acid) is most likely to be released to the environment.


Chemical Properties:    
White Solid

Uses:    
A non-nutritive sweetener.

Definition:    
ChEBI: A member of the class of sulfamic acids that is sulfamic acid carrying an N-cyclohexyl substituent.

General Description:    
The N-cyclohexylsulfamic acid salts of well known therapeutic agents were prepared.

E952 (Cyclamic acid) is a artificially prepared salt of E952 (Cyclamic acid) formerly used as a nonnutritive low-calorie sweetener but now banned because of possible carcinogenic effects of its metabolic products.

IUPAC names
cyclohexylsulfamic acid
N-Cyclohexylsulfamic Acid
N-cyclohexylsulfamic acid
N-cyclohexylsulphamic acid

SYNONYMS:
100-88-9 [RN]
202-898-1 [EINECS]
2208885
Acide cyclohexylsulfamique [French] [ACD/IUPAC Name]
E952 (Cyclamic acid) [BAN] [USAN] [Wiki]
Cyclohexanesulfamic acid
Cyclohexylaminesulfonic acid
Cyclohexylsulfamic acid [ACD/IUPAC Name]
Cyclohexylsulfamidsäure [German] [ACD/IUPAC Name]
GV6950000
HN3OFO5036
MFCD00065234 [MDL number]
N-Cyclohexylsulfamic Acid
Sulfamic acid, N-cyclohexyl- [ACD/Index Name]
[100-88-9]
1215770-73-2 [RN]
139-05-9 [RN]
295-37-4 [RN]
4-12-00-00102 [Beilstein]
4-12-00-00102 (Beilstein Handbook Reference) [Beilstein]
45951-45-9 [RN]
6282-74-2 [RN]
aminocyclohexylsulfonic acid
assugrin
assurgrin feinsuss
assurgrin vollsuss
asugryn
C6H13NO3S
Cyclam [Wiki]
E952 (Cyclamica acid)


 

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