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CAS Reg. No.: 544-63-8
Molar mass: 228.38 g/mol
Empirical formula: C14H28O2
EDENOR C14-99 MY (MYRISTIC ACID) (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH.
EDENOR C14-99 MY (MYRISTIC ACID)'s salts and esters are commonly referred to as myristates or tetradecanoates.
EDENOR C14-99 MY (MYRISTIC ACID) is named after the binomial name for nutmeg (Myristica fragrans), from which EDENOR C14-99 MY (MYRISTIC ACID) was first isolated in 1841 by Lyon Playfair.
A myristate is a salt or ester of EDENOR C14-99 MY (MYRISTIC ACID).
EDENOR C14-99 MY (MYRISTIC ACID) is named after the nutmeg Myristica fragrans.
Nutmeg butter is 75 % trimyristin, the triglyceride of EDENOR C14-99 MY (MYRISTIC ACID).
Besides nutmeg, EDENOR C14-99 MY (MYRISTIC ACID) is also found in palm kernel oil, coconut oil, butter fat and is a minor component of many other animal fats.
EDENOR C14-99 MY (MYRISTIC ACID) is also commonly added co-translationally to the penultimate, nitrogen-terminus, glycine in receptor-associated kinases to confer the membrane localisation of the enzyme.
The EDENOR C14-99 MY (MYRISTIC ACID) has a sufficiently high hydrophobicity to become incorporated into the fatty acyl core of the phospholipid bilayer of the plasma membrane of the eukaryotic cell.
In this way, EDENOR C14-99 MY (MYRISTIC ACID) acts as a lipid anchor in biomembranes.
The ester isopropyl myristate is used in cosmetic and topical medicinal preparations where good absorption through the skin is desired.
Reduction of EDENOR C14-99 MY (MYRISTIC ACID) yields myristyl aldehyde and myristyl alcohol.
EDENOR C14-99 MY (MYRISTIC ACID) is a 14-carbon saturated fatty acid.
EDENOR C14-99 MY (MYRISTIC ACID) is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.
Oily white crystalline solid.
Occurrence
Nutmeg butter has 75% trimyristin, the triglyceride of EDENOR C14-99 MY (MYRISTIC ACID).
Besides nutmeg, EDENOR C14-99 MY (MYRISTIC ACID) is found in palm kernel oil, coconut oil, butterfat, 8–14% of bovine milk, and 8.6% of breast milk as well as being a minor component of many other animal fats.
EDENOR C14-99 MY (MYRISTIC ACID) is also found in the rhizomes of the Iris, including Orris root.
EDENOR C14-99 MY (MYRISTIC ACID) comprises 14.49% of the fats from the fruit of the Durian species Durio graveolens.
Chemical properties
EDENOR C14-99 MY (MYRISTIC ACID) appears as white to yellowish white solid, sometimes appearing as shiny crystalline solid, or white to yellowish white powder.
EDENOR C14-99 MY (MYRISTIC ACID) has a relative density of 0.8739 (80 ℃), melting point of 54.5 ℃ and the boiling point of 326.2 ℃.
EDENOR C14-99 MY (MYRISTIC ACID)'s refractive index (nD60) is 1.4310.
EDENOR C14-99 MY (MYRISTIC ACID) is not soluble in water but soluble in ethanol, ether and chloroform.
EDENOR C14-99 MY (MYRISTIC ACID) contains about 70% to 80% while other kinds of coconut oil, palm kernel oil also contain.
Prepared from the fatty acid mixture of palm seed oil.
EDENOR C14-99 MY (MYRISTIC ACID) occurs as an oily white crystalline solid with a faint odor.
Application
EDENOR C14-99 MY (MYRISTIC ACID) can be used as a chemical agent, also for the synthesis of spices and organic matter.
EDENOR C14-99 MY (MYRISTIC ACID) can be used in the manufacture of emulsifiers, waterproofing agents, curing agents, PVC heat stabilizers and plasticizers, and also used as the raw materials of spices and pharmaceutical.
EDENOR C14-99 MY (MYRISTIC ACID) is mainly used as raw materials for the production of surfactants for the production of sorbitan fatty acid esters, glycerol fatty acid esters, ethylene glycol or propylene glycol fatty acid esters.
EDENOR C14-99 MY (MYRISTIC ACID) can also be used for the production of isopropyl myristate and so on.
EDENOR C14-99 MY (MYRISTIC ACID) can also be used for defoamers and flavoring agent.
According to the provision of China GB2760-89, EDENOR C14-99 MY (MYRISTIC ACID) can be used to prepare a variety of food spices.
EDENOR C14-99 MY (MYRISTIC ACID) is a surfactant and cleansing agent.
When combined with potassium, EDENOR C14-99 MY (MYRISTIC ACID) soap provides very good, abundant lather.
EDENOR C14-99 MY (MYRISTIC ACID) a solid organic acid naturally occurring in butter acids such as nutmeg, oil of lovage, coconut oil, mace oil, and most animal and vegetable fats.
Although some sources cite EDENOR C14-99 MY (MYRISTIC ACID) as having no irritation potential, they do indicate comedogenicity potential.
EDENOR C14-99 MY (MYRISTIC ACID) is a fatty acid obtained from coconut oil and other fats.
EDENOR C14-99 MY (MYRISTIC ACID) has poor water solubility but is soluble in alcohol, chloro- form, and ether.
EDENOR C14-99 MY (MYRISTIC ACID) is used as a lubricant, binder, and defoaming agent.
EDENOR C14-99 MY (MYRISTIC ACID) is a common saturated fatty acid found in nutmeg, palm kernel oil, coconut oil and butter fat.
EDENOR C14-99 MY (MYRISTIC ACID) is a 14-carbon saturated (14:0) fatty acid.
In vivo, EDENOR C14-99 MY (MYRISTIC ACID) is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.
In addition, there are examples where N-myristoylation occurs post-translationally, when a hidden myristoylation pattern is exposed.
EDENOR C14-99 MY (MYRISTIC ACID) Chemical Properties
Melting point : 52-54 °C(lit.)
Boiling point : 250 °C100 mm Hg(lit.)
Density : 0.862
Vapor pressure : <0.01 hPa (20 °C)
FEMA : 2764 | MYRISTIC ACID
Refractive index : nD60 1.4305; nD70 1.4273
Fp : >230 °F
Storage temp.: room temp
Solubility : 1.07mg/l
Form : Flakes, Powder, Chunks or Crystalline Mass
Pka: 4.78±0.10(Predicted)
Color: White
Water Solubility: <0.1 g/100 mL at 18 ºC
Merck: 14,6333
JECFA Number: 113
BRN : 508624
Stability: Stable. Incompatible with strong oxidizing agents, bases.
CAS DataBase Reference: 544-63-8(CAS DataBase Reference)
NIST Chemistry Reference: Tetradecanoic acid(544-63-8)
EPA Substance Registry System: Myristic acid (544-63-8)
Preparation
To prepare theEDENOR C14-99 MY (MYRISTIC ACID), the methyl ester of the mixed fatty acids or mixed fatty acid methyl ester obtained from the coconut oil or palm kernel oil is subject to vacuum fractionation, obtaining EDENOR C14-99 MY (MYRISTIC ACID).
For laboratory preparation, glycerol tris (tetradecanoate) is subject to saponification with 10% sodium hydroxide solution, further being acidified with hydrochloric acid to obtain the free EDENOR C14-99 MY (MYRISTIC ACID).
EDENOR C14-99 MY (MYRISTIC ACID) can also be made from tetradecanol.
Production Methods
EDENOR C14-99 MY (MYRISTIC ACID) occurs naturally in nutmeg butter and in most animal and vegetables fats.
Synthetically, EDENOR C14-99 MY (MYRISTIC ACID) may be prepared by electrolysis of methyl hydrogen adipate and decanoic acid or by Maurer oxidation of myristyl alcohol.
Reactivity Profile
EDENOR C14-99 MY (MYRISTIC ACID) is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.
Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.
Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions.
The pH of solutions of carboxylic acids is therefore less than 7.0.
Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.
Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in EDENOR C14-99 MY (MYRISTIC ACID) to corrode or dissolve iron, steel, and aluminum parts and containers.
Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.
Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.
Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.
A wide variety of products is possible.
Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.
Synonyms
Tetradecanoic acid
MYRISTIC ACID
544-63-8
n-Tetradecanoic acid
Crodacid
n-Tetradecoic acid
n-Tetradecan-1-oic acid
1-Tridecanecarboxylic acid
tetradecoic acid
Hydrofol acid 1495
Univol U 316S
Emery 655
Myristinsaeure
Myristate
Hystrene 9014
Neo-fat 14
C14 fatty acid
Myristic acid, pure
n-Myristic acid
Myristic acid (natural)
FEMA No. 2764
Tetradecanoate
acide tetradecanoique
NSC 5028
CCRIS 4724
CH3-[CH2]12-COOH
HSDB 5686
C14:0
UNII-0I3V7S25AW
Philacid 1400
CHEBI:28875
AI3-15381
Prifac 2942
1-tetradecanecarboxylic acid
0I3V7S25AW
CHEMBL111077
NSC5028
NSC-5028
MFCD00002744
DSSTox_CID_1666
n-tetradecan-1-oate
DSSTox_RID_76274
DSSTox_GSID_21666
CAS-544-63-8
Myristic acid [NF]
32112-52-0
EINECS 208-875-2
BRN 0508624
myristoate
myristoic acid
Lead dimyristate
n-Tetradecanoate
Tetradecanoicacid
3usx
Myristic acid pure
Myristic Acid Flake
Hystrene 9514
Kortacid 1499
Edenor C 14
Myristic Acid 655
1-Tridecanecarboxylate
Prifrac 2942
MAGNESIUMARSENATE
Myristic acid, 95%
Myristic acid, natural
tridecanecarboxylic acid
Myristic acid (8CI)
Myristic Acid, Reagent
3v2n
3w9k
Myristic acid, puriss.
Tetradecanoic acid (9CI)
bmse000737
Epitope ID:176772
SCHEMBL6374
PHILACID-1400
Myristic acid-[14-13C]
PRIFRAC-2942
4-02-00-01126 (Beilstein Handbook Reference)
MLS002152942
WLN: QV13
Tetradecanoic (Myristic) acid
GTPL2806
DTXSID6021666
s161
HMS3039E15
HMS3648O20
Myristic acid, analytical standard
HY-N2041
ZINC1530417
EINECS 250-924-5
Myristic acid, >=98.0% (GC)
Tox21_201852
Tox21_302781
BDBM50147581
LMFA01010014
s5617
STL185697
Myristic acid, >=95%, FCC, FG
Myristic acid, Sigma Grade, >=99%
AKOS009156714
CCG-266785
DB08231
DS-3833
MCULE-9671122893
NSC 122834
NCGC00091068-01
NCGC00091068-02
NCGC00091068-03
NCGC00256547-01
NCGC00259401-01
AC-34674
BP-27915
SMR001224536
CS-0018531
FT-0602832
FT-0770860
M0476
EN300-78099
C06424
Myristic acid, Vetec(TM) reagent grade, 98%
Q422658
SR-01000854525
SR-01000854525-3
W-109088
F8889-5016
EDAE4876-C383-4AD4-A419-10C0550931DB
UNII-13FB83DEYU component TUNFSRHWOTWDNC-UHFFFAOYSA-N
UNII-5U9XZ261ER component TUNFSRHWOTWDNC-UHFFFAOYSA-N
UNII-96GS7P39SN component TUNFSRHWOTWDNC-UHFFFAOYSA-N
UNII-Q8Y7S3B85M component TUNFSRHWOTWDNC-UHFFFAOYSA-N
UNII-79P21R4317 component TUNFSRHWOTWDNC-UHFFFAOYSA-N
Myristic acid, United States Pharmacopeia (USP) Reference Standard
Tetradecanoic acid; 1-Tridecanecarboxylic acid; n-Tetradecanoic acid
Myristic acid, Pharmaceutical Secondary Standard; Certified Reference Material
