ETHYL ACETATE

ETHYL ACETATE = Ethyl ethanoate = Acetic acid ethyl ester = Acetic ether

CAS Number: 141-78-6
EC number: 205-500-4
MDL number: MFCD00009171
Molecular Formula: C4H8O2

Ethyl acetate is one of the simplest carboxylate esters. 
Ethyl acetate is the flammable, organic ester of ethanol and acetic acid.
Ethyl acetate appears as a clear colorless liquid with a fruity odor. 
Ethyl acetate is the acetate ester formed between acetic acid and ethanol.
Ethyl acetate is found in essentially all organisms, from bacteria to yeast, to plants to humans. 
Ethyl acetate has an ethereal, sweet or fruity odor with a sweet, grape or cherry taste. 
Ethyl acetate is present in confectionery (ethyl acetate is used in artificial fruit essences), perfumes, and fruits.
Ethyl acetate exists in all eukaryotes, ranging from yeast to humans. 
Ethyl acetate is a sweet, anise, and balsam tasting compound. 
Ethyl acetate is found, on average, in the highest concentration within a few different foods, such as milk (cow), pineapples, and sweet oranges and in a lower concentration in safflowers. 
Ethyl acetate has also been detected, but not quantified, in several different foods, such as alcoholic beverages, oxheart cabbages, agaves, chervils, ryes, and peach. 
Ethyl acetate is used in artificial fruit essences. 
In the field of entomology, ethyl acetate is an effective asphyxiant for use in insect collecting and study. 
Ethyl ethanoate is a moderately polar, clear, colorless liquid solvent with a light fruity odor. 
Ethyl Acetate, also known as ethyl ethanoate, is a widely used solvent in organic synthesis that is highly miscible with common organic solvents. 
Ethyl ethanoate is cost-effective, highly effective and is easily broken in both air and water simultaneously.
Ethyl ethanoate can be mixed with non-polar solvents and is also used for extractions. 
Ethyl acetate is an acetate ester, an ethyl ester and a volatile organic compound.
Ethyl acetate was first synthesized from ethanol and acetic acid. 
Ethyl acetates reaction was the classic acid-catalyzed Fischer esterification, which dates back to 1895.
Esters are structurally derived from carboxylic acids by replacing the acidic hydrogen by an alkyl or aryl group. 
An alternative method is the Tishchenko reaction in which acetaldehyde disproportionates in the presence of base to the alcohol and the acid that then esterify in situ. 
Ethyl acetate has a role as a polar aprotic solvent, an EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor, a metabolite and a Saccharomyces cerevisiae metabolite. 
The compound is commonly used as a solvent, in extractions and column chromatography.
Ethyl acetate, also known as 1-acetoxyethane or acetic ester, belongs to the class of organic compounds known as carboxylic acid esters.
Because Ethyl acetate is not hygroscopic, ethyl acetate also keeps the insect soft enough to allow proper mounting suitable for a collection.
In organic and in natural products chemistry ethyl acetate is often used as a solvent for reactions or extractions. 
Ethyl acetate is a potentially toxic compound.
Acetic acid-ethyl ester or ethyl acetate, also known as 1-acetoxyethane or acetic ester, belongs to the class of organic compounds known as carboxylic acid esters. 
In perfumes, Ethyl acetate evaporates quickly, leaving only the scent of the perfume on the skin.
Ethyl acetate is found in many fruits such as pineapples, and sweet oranges and in a lower concentration in safflowers. 
Ethyl acetate has also been detected, but not quantified in, several different foods, such as oxheart cabbages, agaves, chervils, peaches, cereal crops, radishes, fruit juices, beer, wine, spirits etc. 
Ethyl acetate is the most common ester in wine, being the product of acetic acid and ethanol generated during fermentation. 
The aroma of ethyl acetate is most intense in younger wines and contributes towards the general perception of 'fruitiness' in wine. 
Industrially, Ethyl acetate is used as a solvent in glues, nail polish removers, and in the decaffeination process of tea and coffee. 
Ethyl acetate is widely used as an organic solvent because of Ethyl acetates low cost, low toxicity, and agreeable odor. 
Ethyl acetate is also used in paints as an activator or hardener and for colour and inks used to mark fruit or vegetables.  
Ethyl Acetate is a compound produced by yeast that is quantitatively the major ester found in both beer and wine. 
Esters are aromatic compounds formed by the reaction between alcohols and acids. 
Esters are widely found in nature and contribute to the aromas of many varieties of fruit. 
Over 90 esters can occur in beer, and the ethyl esters predominate.
Because ethyl acetate is such an influential part of beer aromatics—for good or ill—brewers seek to control its levels in their beers.
Many factors, in addition to the yeast strain employed, have been found to influence the concentration of ethyl acetate formed during fermentation.
These include fermentation temperature, where an increase from 50°F to 77°F (10°C–25°C) has been found to increase the concentration of ethyl acetate from 12.5 to 21.5 mg/L. 
Ethyl acetate is readily soluble in alcohol, ether, chloroform, fatty oils and essential oils. 
Ethyl acetate is soluble in 12 times the amount of water, in which it slowly decomposes under the influence of light and air to alcohol and acetic acid. 
Therefore the solution slowly turns acid. 
Ethyl acetate is a good solvent for cellulose nitrate, celluloid, oils, chlorinated rubber, colophonium, gum copal, vinyl resins, ect.
Ethyl acetate is considered to be one of the least environmentally harmful of organic solvents.
Ethyl acetate is very effective while it is easily broken down in both air and water. 

Uses and applications of ETHYL ACETATE:
-Adhesives
-Pharmaceuticals and Synthesis industries.
-Nail polish remover
-Cigarettes
-Glue
-Base coats and other manicuring products.
-Paint (as an activator or hardener)
-Confections (as an artificial flavor)
-Paints
-Dry cleaning,
-Stains, 
-Fats and nitrocellulose
-Varnishes
-Lacquers
-Cleaning mixtures
-Perfumes
-Ethyl acetate is used as a solvent for decaffeinating coffee beans. 
-Artificial fruit essences and aroma enhancers
-Artificial flavours for confectionery
-Ice cream and cakes
-As a solvent in many applications (including decaffeinating tea and coffee) for varnishes and paints (nail varnish remover)
-For the manufacture of printing inks and perfumes.
-Ethyl acetate is present in wines.
-Ethyl acetate is released during the production of artificial silk and leather, and during the preparation of photographic films and plates. 
-Ethyl acetate is released during the manufacture of linoleum, and 'plastic' wood, dyes, pharmaceuticals, drug intermediates, acetic acid, artificial fruit flavorings and essences, and perfumes and fragrances.
-Ethyl Acrylate is used in the production of coatings, elastomers, adhesives, thickeners, superabsorbents, acrylic esters, and fiber sizing.
-Ethyl acetate is used as a component of artificial apple, pear, strawberry, raspberry and black current ether; to give aroma to sweets, fruit juices, liqueurs, lemonades, as solvent for collodium cotton, nitro cotton, celluloid, etc., and in the preparation of caffeine-free coffee.
-Ethyl acetate is a specialty chemical with dominant use as a solvent.
-Ethyl Acetate solvent is a viscosity reducer for resins used in photoresist formulations. 
-Ethyl Acetate can also be used as a primary photoresist solvent and is compatible with many resist polymers. 
-High-purity (low-trace metals) solvents are required to make acceptable semiconductor chips, and special handling and storage procedures are used to maintain high purity.
-Ethyl acetate is a solvent used in many contexts, including printing inks, varnishes and car care chemicals, and in the manufacture of plastics and rubber. 
-In the food industry, ethyl acetate is used in the manufacture of flavourings.
-In the pharmaceutical industry as an extraction solvent in the production of pharmaceuticals.
-Ethyl acetate is also a common component of cosmetics and nail polish remover.
-Ethyl Acetate has a sweet smell that is used to bring a fruity flavor to candy, baked goods, gum, etc. 
-Ethyl acetate is also used to extract tobacco from cigarettes, decaffeinate tea leaves, and decaffeinate coffee. 
The process to decaffeinate coffee can take up to ten hours, the green coffee beans are rinsed with an ethyl acetate solution to remove caffeine from them. 
Immersing the green coffee beans in water softens the beans and dissolves the caffeine. 
-Ethyl Acetate is added to the water and the caffeine binds to the chemical due to the water holding all the caffeine instead of the coffee beans holding the caffeine. 
When the water is heated, the ethyl acetate steams off, taking the caffeine with it. 
-Ethyl acetate can also be found in wine. 
Ethyl acetate is also common ester in wines, helping to give wines a fruity flavor.
-Ethyl acetate is used as an artificial flavor in ice creams and cakes.
-Ethyl Acetate is used to extract not only within the pharmaceutical industry and for industrial purposes but also in the food and beverage industry.

Synonyms:
-Acetic ester
-Ethyl ester of acetic acid
-Acetidin
-Acetoxyethane 
-Ethyl acetic ester 
-Vinegar naphtha
-Aethylacetat
-Essigester
-Ethylacetaat
-Ethylester kyseliny octove
-Ethyl ester of acetic acid
-1-Acetoxyethane

Physical and chemical properties of ETHYL ACETATE:
Appearance Form: clear, liquid 
Color: colorless
Physical Form: Liquid
Purity: > 99.0 %wt 
Flash point: 24°F. 
Flash point: -4 °C - closed cup
Non Volatile Matter: < 0.005 g/100ml 
Water Content: < 0.10 %wt
Acid Value: < 0.02 mg KOH/g
Color, APHA: < 10
Specific Gravity: 0.902
Product Type: Solvents > Esters
Odor: No data available 
Odor Threshold: No data available 
pH: No data available 
Melting point/freezing point:
Melting point/range: -84 °C 
Freezing Point: -117°C
Initial boiling point and boiling range: 76,5 - 77,5 °C
Evaporation rate: No data available 
Flammability (solid, gas): No data available 
Upper/lower flammability or explosive limits:
Lower explosion limit: 2,2 %(V)
Vapor pressure: No data available 
Vapor density: No data available
Relative density: No data available 
Partition coefficient n-octanol/water: No data available 
Autoignition temperature: No data available 
Decomposition temperature: No data available 
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available 
Explosion limits: 2.1 % - 11.5%
Oxidizing properties: No data available
Molecular Weight : 88.11 g/mol
Solubility in water 85.3 g/l (20 ºC)
Ignition temperature: 460 ºC

First aid measures of Ethyl ethanoate:
-Description of first-aid measures:
General advice: 
Show this material safety data sheet to the doctor in attendance.
If inhaled: 
After inhalation: fresh air. 
Call in physician.
In case of skin contact: 
In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with water/ shower.
In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most). 
Consult a physician.

Exposure controls/personal protection of Ethyl ethanoate:
-Ingredients with workplace control parameters:
Derived No Effect Level (DNEL)
-Exposure controls:
Personal protective equipment:
Eye/face protection:
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). 
Safety glasses.
Skin protection:
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use.
Splash contact Material: butyl-rubber 
Minimum layer thickness: 0,7 mm 
Break through time: 120 min
Body Protection: Flame retardant antistatic protective clothing. 
Respiratory protection:
Recommended Filter type: 
Filter A (acc. to DIN 3181) for vapours of organic compounds.
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. 
These measures have to be properly documented.
-Control of environmental exposure:
Do not let product enter drains. 
Risk of explosion.

Accidental release measures of Ethyl ethanoate:
-Personal precaution:
Protective equipment and emergency procedures:
Advice for non-emergency personnel: 
Do not breathe vapors 
Aerosols.
Avoid substance contact. 
Ensure adequate ventilation.
Keep away from heat and sources of ignition. 
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains. 
Risk of explosion.
-Methods and materials for containment and cleaning up: 
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly. 
Clean up affected area.

Handling and storage of Acetic acid ethyl ester:
-Precautions for safe handling:
Advice on safe handling:
Work under hood. 
Do not inhale substance/mixture. 
Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion:
Keep away from open flames, hot surfaces and sources of ignition.
Take precautionary measures against static discharge.
Hygiene measures:
Change contaminated clothing. 
Preventive skin protection recommended. 
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep away from heat and sources of ignition.
-Packing: 
In polyethylene drums (net weight 180kg) or iso-tank.
Acetic acid ethyl ester should be kept in a dry, cool and well-ventilated place.
Acetic acid ethyl ester is a corrosive material and Acetic acid ethyl ester should be stored in a separated and approved area.
Keep away from sources of ignition.

Stability and reactivity of Acetic acid ethyl ester:
-Reactivity: 
Vapors may form explosive mixture with air
Reactivity Profile:
ETHYL ACETATE is also sensitive to heat. 
On prolonged storage, materials containing similar functional groups have formed explosive peroxides. 
This chemical may ignite or explode with lithium aluminum hydride. 
ETHYL ACETATE may also ignite with potassium tert-butoxide. 
ETHYL ACETATE is incompatible with nitrates, strong alkalis and strong acids. 
ETHYL ACETATE will attack some forms of plastics, rubber and coatings. 
ETHYL ACETATE is incompatible with oxidizers such as hydrogen peroxide, nitric acid, perchloric acid and chromium trioxide. 
Violent reactions occur with chlorosulfonic acid. 
SOCl2 reacts with esters, such as ethyl acetate, forming toxic SO2 gas and water soluble/toxic acyl chlorides, catalyzed by Fe or Zn.
-Chemical stability: The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
Risk of ignition or formation of inflammable gases or vapours with: 
Exothermic reaction with: 
Fluorine 
Chlorosulfonic acid 
Strong oxidizing agents 
Fuming sulfuric acid
Risk of explosion with: 
Lithium aluminium hydride
Alkali metals 
Hydrides 
Alkaline earth metals 
Violent reactions possible with: 
Strong acids and strong bases
-Conditions to avoid: Warming. 
-Incompatible materials: various plastics

Firefighting measures of Acetic acid ethyl ester:
-Extinguishing media:
Suitable extinguishing media: 
Carbon dioxide (CO2) Foam Dry powder 
Unsuitable extinguishing media: 
For this substance/mixture no limitations of extinguishing agents are given.
-Special hazards arising from the substance or mixture:
Carbon oxides Combustible. 
Pay attention to flashback. 
Vapors are heavier than air and may spread along floors. 
Risk of dust explosion. 
Development of hazardous combustion gases or vapours possible in the event of fire. 
Forms explosive mixtures with air at ambient temperatures.
-Advice for firefighters: 
In the event of fire, wear self-contained breathing apparatus
-Further information: 
Remove container from danger zone and cool with water. 
Prevent fire extinguishing water from contaminating surface water or the ground water system.
FIRE & EXPLOSION of Acetic acid ethyl ester:
-ACUTE HAZARDS:
HIGHLY FLAMMABLE:
Will be easily ignited by heat, sparks or flames. 
Vapors may form explosive mixtures with air. 
Vapors may travel to source of ignition and flash back. 
Most vapors are heavier than air.
They will spread along ground and collect in low or confined areas (sewers, basements, tanks).
Vapor explosion hazard indoors, outdoors or in sewers. 
Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. 
Runoff to sewer may create fire or explosion hazard. 
Containers may explode when heated. 
Heating will cause rise in pressure with risk of bursting. 
-PREVENTION:
NO open flames
NO sparks and NO smoking.  
Closed system, ventilation, explosion-proof electrical equipment and lighting. 
Use non-sparking handtools. 
Do NOT use compressed air for filling, discharging, or handling. 
-FIRE FIGHTING:
Use alcohol-resistant foam, foam, powder, carbon dioxide, fine water spray.  
In case of fire: 
Keep drums, etc.
Cool by spraying with water. 

Disposal considerations of Acetic acid ethyl ester:
-SPILLAGE DISPOSAL:
Remove all ignition sources. 
Evacuate danger area! 
Consult an expert! 
Personal protection: 
Filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. 
Do NOT wash away into sewer. 
Collect leaking and spilled liquid in sealable containers as far as possible. 
Absorb remaining liquid in sand or inert absorbent. 
Then store and dispose of according to local regulations. 

Substituents of
-Carboxylic acid ester
-Monocarboxylic acid or derivatives
-Organic oxygen compound
-Organic oxide
-Hydrocarbon derivative
-Organooxygen compound
-Carbonyl group
-Aliphatic acyclic compound

SPECIFICATION:
Item: Standard 
Appearance: Clear, colorless liquid with a pungent odor 
Purity % : 99.5 Min.
Water,% : 0.05 Max.
Color (APHA): 10 Max. 
Acidity(AS AA),%  : 0.005 Max. 
Inhibitor (MEHQ),ppm:  15+5