ETHYLENEDIAMINE (EDA)

Ethylenediamine (EDA) is the lowest molecular weight ethylenediamine. 
Ethylenediamine (EDA) is a single-component product with two primary nitrogens. 
Ethylenediamine (EDA) has an ammonia-like odor and is clear and colorless.

CAS Number: 107-15-3
Molecular Formula: C2H8N2
Molecular Weight: 60.1
EINECS Number: 203-468-6

Synonyms: 391624-46-7, MONO-FMOC ETHYLENE DIAMINE HYDROCHLORIDE, 166410-32-8, (9H-fluoren-9-yl)methyl (2-aminoethyl)carbamate hydrochloride, N-Fmoc-ethylenediamine hydrochloride, Fmoc-EDA.HCl, Mono-fmoc ethylene diamine, HCl, (9H-FLUOREN-9-YL)METHYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE, MFCD00830741, 9H-fluoren-9-ylmethyl N-(2-aminoethyl)carbamate;hydrochloride, (9H-Fluoren-9-yl)methyl 2-aminoethylcarbamate hydrochloride, 9H-fluoren-9-ylmethyl N-(2-aminoethyl)carbamate Hydrochloride, N-1-Fmoc-1,2-diaminoethane . HCl, Fmoc-EDA HCl, N-Fmoc-ethylenediamine HCl, C17H18N2O2.HCl, SCHEMBL966018, Fmoc-NH-(CH2)2-NH2.HCl, DTXSID10937196, AKOS015901130, FS-5255, SY059472, DB-043650, DB-119935, CS-0128625, W12365, EN300-6759619, mono-Fmoc ethylene diamine hydrochloride, AldrichCPR, (9H-fluoren-9-yl)methyl(2-aminoethyl)carbamatehydrochloride, 9H-9-fluorenylmethyl N-(2-aminoethyl)carbamate hydrochloride, N-(9-FLUORENYLMETHYLOXYCARBONYL)-ETHYLENEDIAMINE HYDROCHLORIDE, (9H-Fluoren-9-yl)methyl hydrogen (2-aminoethyl)carbonimidate--hydrogen chloride (1/1), EthylenediaMine purified by redistillation, >=99.5%;Ethylendiaminum;EthylenediaMine, 99+%, AcroSeal;ETHYLENEDIAMINE FOR SYNTHESIS;EDA EthylenediaMine a;amerstat274;beta-Aminoethylamine;caswellno437

Ethylenediamine (EDA) is a clear and colorless product at normal temperature and pressure which has a characteristic smell of an amine. 
Ethylenediamine (EDA) is strongly alkaline and is miscible with water and alcohol. 
Ethylenediamine (EDA) is air sensitive and hygroscopic and absorbs carbon dioxide from the air. 

Ethylenediamine (EDA) is incompatible with aldehydes, phosphorus halides, organic halides, oxidising agents, strong acids, copper, its alloys, and its salts.
Ethylenediamine (EDA) is used in numerous industrial proces ses as a solvent for casein or albumin, as a stabilizer in rubber latex and as a textile lubricant. 
It can be found in epoxy-resin hardeners, cooling oils, fungicides, and waxes. Contact dermatitis from ethylenediamine is almost exclusively due to topical medicaments. 

Occupational contact dermatitis in epoxy-resin systems is rather infrequent. Ethylenediamine can cross react with triethylenetetramine and diethylenetriamine. 
Ethylenediamine (EDA) was responsible for sensitization in pharmacists handling aminophylline suppositories, in nurses preparing and administering injectable theophylline, and in a laboratory technician in the manufacture of aminophylline tab lets.
Ethylenediamine (EDA) is a linear aliphatic diamine, widely used as a building block in organic synthesis. 

Ethylenediamine (EDA) readily forms heterocyclic imidazolidine derivatives, because of its bifunctional nature, having two amines. 
Ethylenediamine (EDA) is also utilized as a raw material for the synthesis of chelating agents, polymers, agrochemicals and pharmaceutical intermediates.
Ethylenediamine (EDA) is an organic chemical compound with the molecular formula C₂H₈N₂, characterized by its two amine (-NH₂) groups attached to a two-carbon ethylene (-CH₂CH₂-) chain. 

This compound is a colorless liquid at room temperature and possesses a strong ammonia-like odor, which can be quite pungent. 
As a diamine, Ethylenediamine (EDA) is a member of the aliphatic amine family and is highly reactive due to its two primary amine groups, making it a versatile compound in a wide range of chemical reactions and industrial applications.
Ethylenediamine (EDA) is highly soluble in water and many organic solvents, forming hydrogen bonds readily due to its amine groups. 

Its chemical structure allows it to act as both a nucleophile and a ligand, enabling it to participate in complexation with metal ions and in various substitution reactions. 
In industrial processes, Ethylenediamine (EDA) is often utilized as a building block for synthesizing other compounds, particularly in the production of polymers, resins, and specialty chemicals.
Ethylenediamine (EDA) is also known for its role in the synthesis of chelating agents like ethylenediaminetetraacetic acid (EDTA), a widely used agent for binding metal ions in various applications, including water treatment and analytical chemistry. 

Additionally, Ethylenediamine (EDA) serves as a critical intermediate in manufacturing emulsifiers, detergents, and pharmaceutical products, showcasing its broad applicability across diverse sectors.
Ethylenediamine (EDA) can be synthesized from ethanolamine (EA) with ammonia over acidic types of zeolite catalyst.
It is produced industrially by the reaction of 1,2-dichloroethane with ammonia in a liquid base under high temperature and high presseure.

The synthesis of ethylenediamine from 1,2-dichloroethane is ClCH2CH2Cl + 2NH3 → NH2CH2CH2NH2*2HCl
ClCH2CH2Cl + NH2CH2CH2NH2*2HCl + 2NH3 → NH2CH2C H2NHCH2CH2NH3*3HCl + NH4HCl
Nevertheless, there are too many byproducts during the reaction. 

The key of this synthesis is to improve the selectivity of reaction product and the application of advanced separation methods to obtain high product purity.
Ethylenediamine (EDA) is used as a building block for the synthesis of bleach activators, chelates and crop protection products. 
Furthermore, it is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.   

Chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from Ethylenediamine (EDA) are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.
Polyamide resins find wide use as binders in printing inks for flexogravure application on certain paper, film, and foil webs and in hot-melt, pressure-sensitive, and heat-seal adhesives for leather, paper, plastic, and metal. 

The main polyamide resin type, in addition to the liquid resins used as epoxy hardeners, is prepared generally by the condensation reaction of diamines with di- and polybasic fatty acids. 
Thermoplastic polyamides are similarly used in formulating glossy, abrasion-resistant, overprint varnishes.
Ethylenediamine (EDA) is a strongly basic amine with an ammonia-like odour. 

The most prominent derivative of ethylenediamine is Ethylenediamine (EDA), a chelating agent. 
Ethylenediamine (EDA) is used in the production of the bleaching activator tetraacetylethylenediamine (TEAD), in electroplating baths, in the production of polyurethane fibres, and polyols and rubber chemicals.
Ethylenediamine (EDA) is used mainly as a building block for crop protection products, in the synthesis of chelating agents and for low-temperature-active bleaching agents.

The other applications of EDA include polyamides, lubricants, fuel additives and textiles.
Ethylenediamine (EDA) is the organic compound with the formula C2H4(NH2)2. 
This colorless liquid with an ammonia-like odor is a basic amine. 

It is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine (EDA) is the first member of the so-called polyethylene amines.
Ethylenediamine (EDA) is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.

In this reaction hydrogen chloride is generated, which forms a salt with the amine. 
The amine is liberated by addition of sodium hydroxide and can then be recovered by fractional distillation.
Ethylenediamine (EDA) and triethylenetetramine (TETA) are formed as by-products.

Ethylenediamine (EDA), because it contains two amine groups, is a widely used precursor to various polymers. Condensates derived from formaldehyde are plasticizers. 
Ethylenediamine (EDA) is widely used in the production of polyurethane fibers. 
The PAMAM class of dendrimers are derived from Ethylenediamine (EDA).

Ethylenediamine (EDA) is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand. 
Ethylenediamine (EDA) is often abbreviated "en" in inorganic chemistry. 
The complex [Co(en)3]3+ is a well studied example. 

Schiff base ligands easily form from ethylenediamine. For example, the diamine condenses with 4-Trifluoromethylbenzaldehyde to give to the diimine.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.
Ethylenediamine (EDA) is the lowest molecular weight ethyleneamine. 

Ethylenediamine (EDA) contains two primary nitrogens. 
Ethylenediamine (EDA) is a single-component product that is clear and colorless, with an ammonia-like odor.
However, Ethylenediamine (EDA) is a highly reactive and volatile substance, requiring careful handling and storage to mitigate potential hazards. 

Its reactivity and strong alkaline nature make it corrosive to skin and eyes, and it can also irritate the respiratory system when inhaled. 
Moreover, Ethylenediamine (EDA) can form explosive mixtures with air under certain conditions, necessitating strict safety measures to prevent accidents during its use and transportation.
One of the defining properties of Ethylenediamine (EDA) is its ability to participate in hydrogen bonding, which contributes to its exceptional solubility in water and many organic solvents. 

This high solubility and reactivity make Ethylenediamine (EDA) a critical reagent in a variety of chemical transformations, especially those involving condensation, alkylation, and polymerization reactions. 
The presence of two amine groups also allows it to act as a bidentate ligand, enabling its use in forming stable coordination complexes with metal ions. 
This property underpins its use in applications ranging from catalysis to water purification.

Ethylenediamine (EDA) is prominently used in the production of ethylenediaminetetraacetic acid (EDTA), a powerful chelating agent that binds to metal ions with high affinity. 
Ethylenediamine (EDA) plays an essential role in various fields, including medicine, where it is used to treat heavy metal poisoning, and in industrial water treatment, where it prevents the buildup of scale and corrosion in pipes. 
Beyond chelation, Ethylenediamine (EDA) is a precursor in manufacturing polyamides, epoxy curing agents, and textile additives, all of which rely on its bifunctional amine groups for crosslinking and structural modifications.

In the pharmaceutical industry, Ethylenediamine (EDA) serves as a raw material for synthesizing active pharmaceutical ingredients (APIs), where its reactive amine groups facilitate the introduction of functional groups into complex molecules. 
Similarly, in the agrochemical sector, EDA is used to produce fungicides, herbicides, and other crop protection chemicals. 
Its versatility extends to the personal care and cosmetics industry, where derivatives of Ethylenediamine (EDA) are employed in hair conditioners and other formulations to enhance product performance.

Despite its wide-ranging uses, Ethylenediamine (EDA) is classified as a hazardous substance due to its potential risks to human health and safety. 
Ethylenediamine (EDA) is highly corrosive and can cause severe skin burns and eye damage upon direct contact. 

Inhalation of Ethylenediamine (EDA) vapors can irritate the respiratory tract, leading to coughing, throat discomfort, and, in severe cases, respiratory distress. 
Prolonged or repeated exposure can result in sensitization, causing allergic reactions in susceptible individuals even at low concentrations.

Melting point: 8.5 °C (lit.)
Boiling point: 118 °C (lit.)
Density: 0.899 g/mL at 25 °C (lit.)
vapor density: 2.07 (vs air)
vapor pressure: 10 mm Hg ( 20 °C)
refractive index: n20/D 1.4565(lit.)
Flash point: 93 °F
storage temp.: Flammables area
solubility: ethanol: soluble(lit.)
pka: 10.712(at 0℃)
form : Liquid, Fuming In Air
Specific Gravity: 0.899
color: colorless to pale yellow
PH: 12.2 (100g/l, H2O, 20℃)
Odor: Strong ammoniacal odor; ammonia-like mild and ammoniacal odor.
explosive limit    2-17%(V)
Water Solubility: miscible
Sensitive: Air Sensitive
Merck: 14,3795
BRN: 605263
Henry's Law Constant: 1.69(x 10-9 atm?m3/mol) at 25 °C (Westheimer and Ingraham, 1956)
Exposure limits    TLV-TWA 10 ppm (～25 mg/m3) (ACGIH, MSHA, and OSHA); IDLH 2000 ppm (NIOSH).
Dielectric constant: 16.0（18℃）
InChIKey: PIICEJLVQHRZGT-UHFFFAOYSA-N
LogP: -1.6 at 20℃

Ethylenediamine (EDA) is a small organic compound that serves as a fundamental building block in the chemical industry, with the molecular structure H₂N-CH₂-CH₂-NH₂, reflecting its two primary amine groups attached to an ethylene backbone. 
Ethylenediamine (EDA) is a clear, colorless liquid at ambient conditions, although it emits a strong, distinctive ammonia-like odor that can be irritating. 
This pungent smell is a characteristic of amines, particularly those with a low molecular weight like Ethylenediamine (EDA). 

Due to its highly reactive nature and versatile amine functionality, EDA is extensively utilized in both industrial and scientific contexts.
Ethylenediamine (EDA) is important in inorganic chemistry because it may function as a bidentantate ligand, coordinating to a metal ion by the lone pairs on the two nitrogen atoms. 
In the names of complexes it is given the abbreviation en.

Ethylenediamine (EDA) highly reactive with many compounds. 
Can react violently with acetic acid, acetic anhydride, acrolein, acrylic acid, acrylonitrile, allyl chloride, carbon disulfide, chlorosulfonic acid, epichlorohydrin, ethylene chlorohydrin, hydrogen chloride, mesityl oxide, nitric acid, oleum, AgClO4, sulfuric acid, beta-propiolactone and vinyl acetate. 
Incompatible with strong acids, strong oxidizers (perchlorate salts), and chlorinated organic compounds. 

Ethylenediamine (EDA) is also incompatible with halogenated organic compounds and metal halides. 
May react with nitromethane and diisopropyl peroxydicarbonate. 
May ignite on contact with cellulose nitrate. 

Readily absorbs carbon dioxide from the air to give crusty solid deposits.
Ethylenediamine (EDA) reacts violently with ethylene chlorohydrin. 
Ethylenediamine (EDA) is used as an intermediate; as a urine acidifier; as a solvent; an emulsifier for casein and shellac solutions; a stabilizer in rubber late. 

A chemical intermediate in the manufacture of dyes; corrosion inhibitors; synthetic waxes; fungicides, resins, insecticides, asphalt wetting agents; and pharmaceuticals. 
Ethylenediamine (EDA) is a degradation product of the agricultural fungicide Maneb.
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. 

If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water.
If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. 
Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. 

Do not induce vomiting. Medical observation is recommended for 2448 h after breathing overexposure, as pulmonary edema may be delayed. 
As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a corticosteroid spray.
Vapor may form explosive mixture with air. 

Ethylenediamine (EDA) is a medium strong base. 
Violent reaction with strong acids; strong oxidizers; chlorinated organic compounds; acetic acid; acetic anhydride; acrolein, acrylic acid; acrylonitrile, allyl chloride; carbon disulfide; chlorosulfonic acid; epichlorohydrin, ethylene chlorohydrin, oleum, methyl oxide; vinyl acetate. 
Also incompatible with silver perchlorate, 3-propiolactone, mesityl oxide; ethylene dichloride; organic anhydrides; isocyanates, acrylates, substituted allyls; alkylene oxides; ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. 

Attacks aluminum, copper, lead, tin, zinc, and alloys; some plastics, rubber, and coatings.
Ethylenediamine (EDA) is the lowest molecular weight ethyleneamine. 
It contains two primary nitrogens. 

Ethylenediamine (EDA) is a single-component product that is clear and colorless, with an ammonia-like odor.
A most prominent derivative of ethylenediamine is the chelating agent EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde. 
Ethylenediamine (EDA) is another commercially significant chelating agent.

Numerous bio-active compounds and drugs contain the N–CH2–CH2–N linkage, including some antihistamines.
Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brand names Maneb, Mancozeb, Zineb, and Metiram. 
Some imidazoline-containing fungicides are derived from ethylenediamine.

Ethylenediamine (EDA) is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ingredient theophylline. 
Ethylenediamine (EDA) has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.
When used as a pharmaceutical excipient, after oral administration its bioavailability is about 0.34, due to a substantial first-pass effect. 

Ethylenediamine (EDA)-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline. 
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family).

Furthermore, Ethylenediamine (EDA) is volatile and flammable, capable of forming explosive mixtures with air, especially in confined spaces or at elevated temperatures. 
This property necessitates stringent storage and handling protocols, including the use of flame-resistant containers and properly ventilated environments. 
The reactivity of Ethylenediamine (EDA) with acids, oxidizing agents, and certain metals adds another layer of complexity to its safe usage, as such interactions can result in violent reactions or the release of toxic gases.

In environmental contexts, Ethylenediamine (EDA) poses potential risks due to its aquatic toxicity and persistence. While not readily biodegradable, its amine groups can react with environmental components, leading to the formation of derivatives that may have adverse ecological impacts. 
For this reason, proper disposal methods and containment strategies are critical to minimize its environmental footprint.

Uses:
Ethylenediamine (EDA) is used as a stabilizerfor rubber latex, as an emulsifier, as aninhibitor in antifreeze solutions, and intextile lubricants. 
It is also used as a solvent for albumin, shellac, sulfur, and othersubstances.
With the two nitrogen atoms, which can donate their lone pairs of electrons, Ethylenediamine (EDA) is widely used as a chelating ligand for coordination chemistry to form bonds to a transition-metal ion such as nickel (II).

The bonds form between the metal ion and the nitrogen atoms of ethylenediamine. 
Ethylenediamine (EDA) is a derivate of ethylenediamine and it is a versatile chelating agent, which could form chelates with both transition-metal ions and main-group ions. 
Ethylenediamine (EDA) is mainly used to synthesize ethylenediaminetetraacetic acid. 

Ethylenediamine (EDA) is frequently used in soaps and detergents to form complexes with calcium and magnesium ions in hard water to improve the cleaning efficiency. 
Furthermore, Ethylenediamine (EDA) is used extensively as a stabilizing agent in the food industry to promote color retention, to improve flavor retention, and to inhibit rancidity.
Ethylenediamine (EDA) is used to facilitate the dissolution of theophylline. 

This combination is known as aminophylline and used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g. asthma, emphysema, chronic bronchitis).
Ethylenediamine (EDA) is evidenced that there is no molecular association between theophylline and ethylenediamine in biological media. 
The bioavailability of ethylenediamine is approximately 34% and of theophylline is about 88%.5

Ethylenediamine (EDA) is used as an intermediate in the manufacture of tetraacetyl ethylenediamine (TAED), a bleaching activator, which is used in detergents and additives for laundry washing and dishwashing.
The amount of TAED used in household cleaning products in Europe was estimated to be 61,000 t in 2001.
Ethylenediamine (EDA) is in the manufacture of organic flocculants, urea resins, and fatty bisamides. 

It is used in the production of formulations for use in the printed circuit board and metal finishing industries. 
Ethylenediamine (EDA) is used as intermediate in the production of crop protection agents, hardeners for epoxy resins, leather industry, paint industry, fungicides in crop protection area, and textile industry.
Ethylenediamine (EDA) is also used as solvent and for the analytical chemistry. 

Ethylenediamine (EDA) is used to produce photographic fixer additive
Intermediate in the manufacture of Ethylenediamine (EDA); catalytic agent in epoxy resins; dyes, solvent stabilizer; neutralizer in rubber products Ethylenediamine (EDA) functions as a reactive intermediate in the synthesis of carbamate fungicides and in the preparation of dyes, synthetic waxes, resins, insecticides and asphalt wetting agents. 

Ethylenediamine (EDA) is a solvent for casein, albumin, shellac, and sulfur; an emulsifier; a stabilizer for rubber latex; an inhibitor in antifreeze solutions; and a pharmaceutic aid (aminophylline injection stabilizer). 
Ethylenediamine (EDA) is also an important ingredient in hair-settings, cold wave lotions, and nail polish.
Ethylenediamine (EDA) is used in numerous industrial processes as a solvent for casein or albumin, as a stabilizer in rubber latex, and as a textile lubricant. 

Ethylenediamine (EDA) can be found in epoxy resin hardeners, cooling oils, fungicides, and waxes. 
Contact dermatitis from ethylenediamine is almost exclusively due to topical medicaments. 
Occupational contact dermatitis in epoxy resin systems is rather infrequent. 

Ethylenediamine (EDA) can crossreact with triethylenetetramine and diethylenetriamine. 
Ethylenediamine (EDA) was found to be responsible for sensitization in pharmacists handling aminophylline suppositories, in nurses preparing and administering injectable theophylline, and in a laboratory technician in the manufacture of aminophylline tablets
Ethylenediamine (EDA) is used in large quantities for production of many industrial chemicals. 

Ethylenediamine (EDA) forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones. Because of its bifunctional nature, having two amino groups, it readily forms heterocycles such as imidazolidines.
Release to the environment of Ethylenediamine (EDA) can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.
Ethylenediamine (EDA) can be found in products with material based on: wood (e.g. floors, furniture, toys).

Ethylenediamine (EDA) is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.
Ethylenediamine (EDA) is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.

Other release to the environment of Ethylenediamine (EDA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Ethylenediamine (EDA) is used in the following products: fuels.

Ethylenediamine (EDA) has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediamine (EDA) can occur from industrial use: formulation of mixtures.
Ethylenediamine (EDA) is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.

Ethylenediamine (EDA) has an industrial use resulting in manufacture of another substance (use of intermediates).
Ethylenediamine (EDA) is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine (EDA) is used for the manufacture of: chemicals.

Release to the environment of Ethylenediamine (EDA) can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.
Ethylenediamine (EDA) is a highly versatile chemical with a wide range of applications across various industries due to its dual amine groups, which make it an essential building block for numerous products. 

One of its most prominent uses is in the production of ethylenediaminetetraacetic acid (EDTA), a powerful chelating agent that binds to metal ions. 
Ethylenediamine (EDA) has extensive applications in water treatment systems to prevent scale formation and corrosion in pipes, in the medical field for chelation therapy to treat heavy metal poisoning, and in food preservation to maintain product quality by binding trace metals.
Ethylenediamine (EDA) is also a critical component in the manufacture of epoxy curing agents, which are vital for producing high-performance coatings, adhesives, and composites. 

These materials are used in industries ranging from aerospace and automotive to construction, where durability and strength are paramount. 
The reactivity of Ethylenediamine (EDA) allows it to crosslink with epoxy resins, creating a robust and chemically resistant network that enhances the performance of these materials in demanding environments.
In the polymer industry, Ethylenediamine (EDA) serves as a precursor for synthesizing polyamides, including nylon and other specialty plastics. 

These polymers are used in the production of textiles, packaging materials, and engineering plastics due to their excellent mechanical properties and resistance to wear and chemicals. 
Furthermore, Ethylenediamine (EDA) is used to create synthetic lubricants and fuel additives that improve engine performance by reducing friction and preventing the buildup of deposits.
The pharmaceutical industry leverages Ethylenediamine (EDA) in the synthesis of active pharmaceutical ingredients (APIs) and as an intermediate in the production of antihistamines, sedatives, and other therapeutic agents. 

Its amine groups facilitate the introduction of functional groups into complex organic molecules, enabling the development of drugs with specific biological activities. 
Additionally, Ethylenediamine (EDA) derivatives are used in agrochemical formulations, such as fungicides, herbicides, and pesticides, which enhance crop yield and protect against pests and diseases.
In personal care products, Ethylenediamine (EDA) derivatives are utilized in formulations like hair conditioners and skin care products to improve texture, enhance stability, and optimize performance. 

In textile processing, Ethylenediamine (EDA) is used as a textile finishing agent to impart wrinkle resistance and improve dye fixation, ensuring vibrant and durable fabrics. 
Moreover, its role as a dispersant and emulsifier in detergents and cleaning agents ensures effective removal of dirt and grease in household and industrial cleaning applications.
Ethylenediamine (EDA) is also an essential raw material in the chemical synthesis of surfactants and corrosion inhibitors. 

These substances are critical in oilfield applications, such as drilling and pipeline maintenance, where they prevent equipment damage and enhance efficiency. 
In addition, Ethylenediamine (EDA) is employed in producing chemical intermediates for rubber processing, adhesives, and sealants, demonstrating its versatility and indispensability in industrial processes.

Health Hazard:
Ethylenediamine (EDA) is a severe skin irritant, producing sensitization, an allergic reaction andblistering on the skin. 
Pure liquid on contact with the eyes can damage vision. 
A25% aqueous solution can be injurious to theeyes. 

Inhalation of its vapors can producea strong irritation to the nose and respiratory tract leading to chemical pneumonitis and pulmonary edema. 
Such irritation inhumans with symptoms of cough and dis tressed breathing may be noted at concentrations of >400 ppm. 
Repeated exposure tohigh concentrations of this substance in airmay cause lung, liver, and kidney damage.

The toxicity of this compound, however, is much less than that of ethylenimine.
The acute oral toxicity value in animalswas low to moderate. An oral LD50 value inrats is 500 mg/kg.
Human subjects found 100 p.p.m. Ethylenediamine (EDA) for a few seconds to be inoffensive but higher concentrations of 200 and 400 p.p.m. produced noticeable irritation of the nasal mucosa. 

Acute Ethylenediamine (EDA) ingestion will cause burns of the mouth, esophagus and possibly stomach. 
Eye contact would be expected to produce a serious burn due to the corrosiveness of the compound. 
Acute exposure to the skin is likely to produce a skin burn, while chronic exposure will cause a serious burn.

Safety Profile:
A human poison by inhalation. 
Experimental poison by inhalation, intraperitoneal, subcutaneous, and intravenous routes. 
Moderately toxic by ingestion and skin contact, Experimental reproductive effects.  

Flammable liquid when exposed to heat, flame, or oxidizers. 
Can react violently with acetic acid, acetic anhydride, acrolein, acrylic acid, acrylonitrile, allyl chloride, CS2, chlorosulfonic acid, epichlorohydrin, ethylene chlorohydrin, HCl, mesityl oxide, HNO3, oleum, AgClO4, H2SO4, Ppropiolactone, or vinyl acetate. 
To fight fwe, use CO2, dry chemical, alcohol foam. When heated to decomposition it emits toxic fumes of NOx and NH3. 

Ethylenediamine (EDA), like ammonia and other low-molecular weight amines, is a skin and respiratory irritant. 
Unless tightly contained, liquid Ethylenediamine (EDA) will release toxic and irritating vapors into its surroundings, especially on heating.

The vapors absorb moisture from humid air to form a characteristic white mist, which is extremely irritating to skin, eyes, lungs and mucous membranes.