GLYCINE

Glycine is the simplest amino acid used in food, pharmaceutical, cosmetic, feed, and industrial applications, and Glycine is valued for its mild taste, buffering behavior, nutritional role, and compatibility with many formulation systems.
Glycine is commonly used as a food additive, dietary supplement ingredient, pharmaceutical excipient, buffer component, and intermediate in chemical synthesis, and Glycine performance depends on purity, particle size, solubility, pH behavior, and regulatory grade.
Glycine is typically supplied as a white crystalline powder, and Glycine should be handled with basic dust control practices to maintain product quality and reduce airborne particulate exposure.

CAS Number: 56-40-6
EC Number: 200-272-2
Molecular Formula: C2H5NO2
Molecular Weight: 75.07 g/mol

Synonyms: Glycine, Aminoacetic Acid, Aminoethanoic Acid, Glycocoll, 2-Aminoacetic Acid, 2-Aminoethanoic Acid, Glycine Powder, Glycine USP, Glycine Food Grade, Glycine Pharmaceutical Grade, Glycine Feed Grade, Glycine Technical Grade, Glycine, Aminoacetic Acid, Aminoethanoic Acid, 2-Aminoacetic Acid, 2-Aminoethanoic Acid, Glycocoll, Glycocine, Glycin, Glycocolle, Glycine Free Base, Glycine USP, Glycine EP, Glycine BP, Glycine FCC, Glycine Food Grade, Glycine Pharmaceutical Grade, Glycine Technical Grade, Glycine Industrial Grade, Glycine Reagent Grade, Glycine Laboratory Grade, Glycine Analytical Grade, Glycine Buffer Grade, Glycine Crystalline, Crystalline Glycine, Glycine Powder, Glycine Granules, Glycine Amino Acid, Non-Essential Amino Acid Glycine, Proteinogenic Amino Acid Glycine, Neutral Amino Acid Glycine, Alpha-Aminoacetic Acid, α-Aminoacetic Acid, 2-Aminoethanoic Acid Glycine, Aminoacetic Acid Glycine, Glycine Base, Glycine Supplement Grade, Glycine Nutritional Grade, Glycine Feed Grade, Glycine Pharma Grade, Glycine Food Additive, Glycine Buffering Agent

APPLICATIONS

Glycine is used in food and beverage products as a flavor modifier, sweetness enhancer, and acidity-balancing ingredient.
Glycine is incorporated into seasonings, sauces, soups, and savory products to provide mild sweetness and improve taste balance.
Glycine is used in processed foods in selected applications to reduce harsh acidic or salty notes.

Glycine is used in dietary supplements as an amino acid ingredient supporting nutritional formulations.
Glycine is incorporated into collagen, sleep-support, sports nutrition, and wellness products in compatible dosage forms.
Glycine is used in powder blends, capsules, tablets, and drink mixes where good water solubility and mild taste are useful.

Glycine is used in pharmaceutical formulations as an excipient, stabilizer, and buffering agent.
Glycine is incorporated into injectable, oral, and topical pharmaceutical systems in selected applications where regulatory grade and purity requirements are met.
Glycine is used in antacid and buffering formulations to support pH control and formulation stability.

Glycine is used in cosmetics and personal care products as a skin-conditioning agent, buffering component, and mild humectant-related ingredient.
Glycine is incorporated into creams, lotions, cleansers, and hair care products to support mildness and amino-acid-based positioning.
Glycine is used in skincare formulations where amino acid compatibility and gentle formulation behavior are desired.

Glycine is used in animal nutrition as a feed additive and amino acid source in selected feed formulations.
Glycine is incorporated into premixes and feed supplements where nutritional balance and palatability are important.
Glycine is valued because Glycine provides versatile amino acid functionality, buffering behavior, mild taste, and broad compatibility across food, pharmaceutical, cosmetic, feed, and technical applications.

Glycine is used as a nutritional supplement in food and beverage products. Glycine is used as an amino acid source in dietary formulations. Glycine is applied in sports nutrition products. Glycine supports protein and amino acid enrichment in functional foods.

Glycine is used in pharmaceutical formulations. Glycine acts as an excipient in tablets and capsules. Glycine is used as a buffering agent in medicinal preparations. Glycine helps improve stability in selected pharmaceutical systems.

Glycine is used in injectable and infusion formulations under controlled conditions. Glycine is applied in antacid preparations. Glycine is used in liver-support and metabolic formulations. Glycine is used in wound-healing and clinical nutrition products.

Glycine is used in cosmetic and personal care products. Glycine acts as a skin-conditioning ingredient. Glycine is applied in moisturizing formulations. Glycine helps improve skin feel in creams and lotions.

Glycine is used in hair-care formulations. Glycine is applied in shampoos and conditioners. Glycine is used in cleansing products. Glycine supports mildness in selected surfactant systems.

Glycine is used in amino acid-based surfactant production. Glycine serves as a raw material for glycinates. Glycine is used in the production of metal glycinate complexes. Glycine is applied in mineral supplementation products.

Glycine is used in animal feed formulations. Glycine supports amino acid balance in feed premixes. Glycine is applied in pet food products. Glycine improves palatability in selected animal nutrition systems.

Glycine is used in agriculture as a component of chelated micronutrients. Glycine helps improve nutrient availability in fertilizer formulations. Glycine is applied in foliar nutrient products. Glycine supports plant nutrition through amino acid-based formulations.

Glycine is used in chemical synthesis. Glycine serves as an intermediate for organic compounds. Glycine is used in peptide synthesis. Glycine is applied in the preparation of biochemical reagents.

Glycine is used in laboratory research. Glycine is applied in buffer systems for biochemical analysis. Glycine is used in electrophoresis buffers. Glycine helps maintain ionic strength in protein separation methods.

Glycine is used in cell culture media. Glycine supports amino acid requirements in biological research. Glycine is used in fermentation processes. Glycine serves as a nitrogen source in selected microbial systems.

Glycine is used in metal finishing applications. Glycine acts as a complexing agent in electroplating baths. Glycine helps control metal ion behavior in solution. Glycine is applied in polishing and surface-treatment formulations.

Glycine is used in flavor formulations. Glycine contributes a mild sweet taste in food systems.

DESCRIPTION

Glycine is the simplest naturally occurring amino acid, and Glycine contains both an amino group and a carboxyl group in a small, highly water-compatible molecule.
Glycine is non-chiral because its alpha carbon has two hydrogen atoms, and this distinguishes Glycine from most other amino acids.
Glycine participates in protein structure, collagen composition, bile acid conjugation, glutathione formation, and many biochemical pathways.

Glycine has a mild sweet taste, and this sensory profile supports its use in food and supplement products where taste masking or flavor smoothing is desired.
Glycine can act as a buffering agent in certain pH ranges, and this makes Glycine useful in biochemical, pharmaceutical, and technical formulations.
Glycine should be used according to applicable food, pharmaceutical, cosmetic, feed, or industrial regulations for the target market and application.

Glycine is generally stable under normal dry storage conditions, but Glycine should be protected from moisture and contamination to maintain free-flowing behavior and assay.
Glycine should be stored in tightly closed containers in a cool, dry area.
Glycine should be handled with clean equipment, especially in food, pharmaceutical, and cosmetic applications, to avoid contamination.

Glycine is the simplest amino acid. Glycine is a white crystalline powder. Glycine has a mildly sweet taste. Glycine is odorless under normal conditions.

Glycine is soluble in water. Glycine has limited solubility in many organic solvents. Glycine contains both amino and carboxyl functional groups. Glycine can exist as a zwitterion in aqueous solution.

Glycine is classified as a nonessential amino acid. Glycine is naturally present in proteins and living organisms. Glycine is important in collagen structure. Glycine contributes to metabolic pathways in the body.

Glycine is chemically stable under normal storage conditions. Glycine should be stored in tightly closed containers. Glycine should be protected from moisture and contamination. Glycine is generally handled as a low-hazard solid with normal precautions.

Glycine has amphoteric chemical behavior. Glycine can react with acids and bases. Glycine can form salts and coordination complexes. Glycine is useful because of its buffering and chelating properties.

Glycine is compatible with many food, pharmaceutical, and cosmetic ingredients. Glycine is valued for its high purity and predictable performance. Glycine is widely used in regulated applications when suitable grades are selected. Glycine is an important building block in biochemical and industrial chemistry.

Glycine is a versatile amino acid used across nutrition, research, and manufacturing.

PROPERTIES

Chemical Formula: C2H5NO2
Molecular Weight: 75.07 g/mol
Common Name: Glycine
Chemical Type: Amino acid; nutritional ingredient; buffering agent; pharmaceutical excipient
Appearance: White crystalline powder
Odor: Odorless or nearly odorless
Taste: Mildly sweet
Solubility: Soluble in water; practically insoluble in many nonpolar solvents
Melting/Decomposition Point: Decomposes at high temperature, typically above 230°C
pH Behavior: Amphoteric amino acid; buffering behavior depends on formulation pH
Stability: Stable under normal dry storage conditions
Storage Temperature: 15–30°C, tightly closed, dry
Shelf Life: Typically 24–60 months in original sealed packaging, supplier dependent

FIRST AID

Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during powder handling.

Skin Contact:
Wash skin with soap and water after contact.
Remove contaminated clothing if necessary and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a large amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care as needed.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses for bulk handling.
Avoid generating dust during transfer, weighing, and blending operations.
Use clean, dry equipment to maintain product purity and prevent contamination.

Ventilation:
Use general ventilation for normal handling.
Use local exhaust ventilation where dust may be generated.
Minimize airborne particulate accumulation in enclosed processing areas.

Storage:
Store in tightly closed containers in a cool, dry, well-ventilated area.
Protect from moisture to prevent caking and maintain free-flowing powder quality.
Keep away from strong oxidizers and sources of contamination.

Spill and Leak Procedures:
Sweep or vacuum spilled powder while avoiding dust generation.
Collect into suitable containers for reuse or disposal according to local regulations and facility procedures.
Clean residue with water if needed and dry the area to prevent slip hazards.

Handling Precautions:
Control dust because fine Glycine powder can irritate the respiratory tract during bulk handling.
Select the appropriate regulatory grade because food, pharmaceutical, cosmetic, feed, and technical applications require different quality specifications.
Rotate stock using FIFO practices to maintain consistent quality, assay, and formulation performance.