GYMNEMA SYLVESTRE EXTRACT

Gymnema Sylvestre extract is a plant native to India and Africa with a history of use in Ayurvedic medicine. 
Gymnema Sylvestre extract has little evidence of health benefits.
Gymnema Sylvestre extract contains chemicals that reduce how much sugar the stomach absorbs. 

CAS Number: 90045-47-9

Synonyms: Gymnema sylvestre extract, 90045-47-9, Gymnema silvestre, ext.

Gymnema Sylvestre extract might also increase the amount of insulin in the body and increase the growth of cells in the pancreas, which is where the body makes insulin.
People use Gymnema Sylvestre extract for diabetes, obesity, and many other conditions, but there is no good scientific evidence to support these uses.
Gymnema Sylvestre extract is a woody climbing shrub native to tropical forests in India, Africa, and Australia. 

The plant's name "Gymnema" comes from the Sanskrit word "Gymnema," which means "sugar destroyer," reflecting its traditional use for managing sugar levels.
Gymnema Sylvestre extract is a perennial woody vine native to Asia (including the Arabian Peninsula), Africa and Australia. 
It has been used in Ayurvedic medicine. 

Common names include Gymnema Sylvestre extract, Australian cowplant, and Periploca of the woods, and the Hindi term gurmar, which means "sugar destroyer".
The leaves and extracts contain Gymnema Sylvestre extract, the major bioactive constituents that interact with taste receptors on the tongue to temporarily suppress the taste of sweetness.
The plant is a climber with leaves having soft hairs on the upper surface. 

The leaves are elongated-oval in shape. 
Gymnema Sylvestre extract has a small, yellow, umbelliferous inflorescence that is produced throughout the year.
Its leaves contain triterpenoid saponins, flavonols, and gurmarin.

The major biologically active plant molecules are gymnemic acids, a class of triterpenoid saponins, which have the effect of suppressing the taste of sweetness on the tongue from sucrose (sugar), stevia, xylitol, and artificial sweeteners such as aspartame.
The sweet-blocking effect of G. sylvestre lasts from 15 to 50 minutes and may even persist for several hours.

Gymnema Sylvestre extract apparently have no long-term effects on taste and they do not influence bitter, salty, or sour taste perception.
Effects on sugar absorption and insulin secretion
Gymnema Sylvestre extracts in Gymnema sylvestre can also attach to receptors on the intestinal walls, helping to reduce absorption of sugar molecules in the gut.

This process can lower blood sugar and promote insulin secretion and release.
However, its antidiabetic properties were not confirmed in rats.
Gymnema Sylvestre extract is a woody plant that grows in Southeast Asia and India, where the roots, leaves, and stems have all been used for many years in the ayurvedic system of medicine. 

In Ayurvedic medicine, GS is used for an array of conditions, including asthma, gastrointestinal complaints, urinary infections, snake bites, and as an antibiotic.
Gymnema Sylvestre extract is a woody climbing shrub native to India and Africa. 
The leaves are used to make medicine. 

Gymnema Sylvestre extract has a long history of use in India's Ayurvedic medicine. 
The Hindi name, gurmar, means "destroyer of sugar."
Some people use Gymnema Sylvestre extract supplements as part of their diabetes treatment plan. Some early research suggests it could help.

Combined with diabetes drugs and insulin, Gymnema Sylvestre extract supplements may help lower blood sugar levels in people with types 1 and 2 diabetes. 
However, we need more research to know for sure.
Gymnema Sylvestre extract is a plant used in traditional medicine, particularly in India. 

Its extract is derived from the leaves of the Gymnema Sylvestre extract plant and is commonly used in various supplements and remedies. 
The primary active compounds in Gymnema Sylvestre extract are gymnemic acids, which are believed to block sugar absorption in the intestines and reduce the sweetness of sugar, thereby supporting blood sugar control.
Other constituents include saponins and steroids, which contribute to its various health benefits.

Gymnema Sylvestre extract is often used to support the management of diabetes by helping to lower blood sugar levels and improve insulin function.
Gymnema Sylvestre extract may help reduce sugar cravings and decrease the absorption of sugar in the digestive tract.
Some studies suggest that Gymnema Sylvestre extract can aid in weight management by reducing appetite and sugar cravings.

Gymnema Sylvestre extract may help in regulating digestive processes and supporting overall digestive health.
Preliminary research indicates that Gymnema Sylvestre extract might have a positive effect on cholesterol levels, helping to reduce LDL (bad) cholesterol.
Gymnema Sylvestre extract has anti-inflammatory properties that might support immune function and overall health.

Some studies are exploring Gymnema Sylvestre extract's potential in cancer prevention and treatment, though more research is needed in this area.
Commonly available as dietary supplements in capsule or tablet form.
The dried leaves can be consumed in powdered form or used to make tea.

Gymnema Sylvestre extract available in liquid extracts or tinctures.
Some individuals may experience gastrointestinal discomfort, including nausea or an upset stomach.
Rare allergic reactions can occur, including skin rashes or itching.

In combination with diabetes medications, Gymnema Sylvestre extract may enhance blood sugar-lowering effects, potentially leading to hypoglycemia.
There is limited information on the safety of Gymnema Sylvestre extract during pregnancy and breastfeeding. 

It is best to consult a healthcare provider before use.
Gymnema Sylvestre extract may interact with medications for diabetes or other conditions, so it’s important to consult a healthcare provider before starting Gymnema sylvestre supplements.

Uses Of Gymnema Sylvestre extract:
Gymnema Sylvestre extract taken in the form of lozenges, mouthwash, or tea diminishes the consumption of sweet foods and overall caloric intake. 
Gymnema Sylvestre extract (formulated as a mint lozenge) reduced the desire for high-sugar foods and the pleasant taste of candy.
Research also suggests that Gymnema Sylvestre extract reduce cravings for sugar. 

In a double-blind study, participants who received a gymnemic acid lozenge declined candy (before tasting it) more often than the placebo group.
Weight loss: In Japan, 50 tons of Gymnema Sylvestre extract leaves are consumed annually for the purpose of weight loss.
Early research suggests that taking a specific combination of Gymnema Sylvestre extract, hydroxycitric acid, and niacin-bound chromium by mouth for 8 weeks might reduce body weight in people who are overweight or obese.

In Eastern and Ayurvedic medicine, Gymnema Sylvestre extract leaves and extracts have been used to treat eye diseases, allergies, constipation, cough, dental caries, obesity, stomach ailments, and viral infections. 
Gymnema Sylvestre extract has also been used as an antioxidant, antimicrobial, and aphrodisiac.
The plant has been used in traditional medicine, most notably to control blood glucose, which seems to have the strongest evidence of its historical uses. 

Use as a lipid-lowering agent, for weight loss, and for the inhibition of caries have also been investigated, primarily in rodent studies. 
However, limited clinical information is available to support the use of gymnema for any indication.
Gymnema Sylvestre extract is commonly used to support diabetes management. 

It helps lower blood sugar levels by increasing insulin production and enhancing insulin sensitivity.
Gymnema Sylvestre extract can reduce the absorption of sugar in the intestines and block sugar receptors on the tongue, which helps reduce sugar cravings and consumption.
Gymnema Sylvestre extract may aid in weight management by decreasing appetite, particularly for sugary foods, and reducing overall calorie intake.

Gymnema Sylvestre extract may support healthy digestion and help regulate glycemic control, which is beneficial for managing blood sugar levels.
Some research suggests that Gymnema Sylvestre extract may help lower LDL (bad) cholesterol and improve overall lipid profiles, contributing to cardiovascular health.
The extract has anti-inflammatory properties that may support immune function and help manage inflammatory conditions.

Preliminary studies indicate that Gymnema Sylvestre extract might have anti-cancer properties. 
It may help inhibit the growth of cancer cells, though more research is needed in this area.

Gymnema Sylvestre extract is sometimes used to enhance general well-being, increase energy levels, and improve overall vitality.
Gymnema Sylvestre extract may help with oral health by reducing the growth of bacteria in the mouth and supporting gum health.

Safety Profile Of Gymnema Sylvestre extract:
Some individuals may experience gastrointestinal discomfort, including nausea, stomach upset, or diarrhea.
Gymnema Sylvestre extract may enhance the blood sugar-lowering effects of diabetes medications, potentially leading to hypoglycemia (low blood sugar). 
This can cause symptoms like dizziness, confusion, or fainting.

Rare allergic reactions can occur, including skin rashes, itching, or swelling. Severe reactions are uncommon but can happen.
Gymnema Sylvestre extract may interact with other medications, especially those for diabetes, which could affect blood sugar levels. 
Gymnema Sylvestre extract is important to consult with a healthcare provider to avoid adverse interactions.

There is limited information on the safety of Gymnema Sylvestre extract during pregnancy and breastfeeding. 
Its use is not well-studied in these populations, so it is best to consult a healthcare provider before use.
Some studies suggest that Gymnema Sylvestre extract may affect iron absorption, which could be a concern for individuals with iron deficiency or anemia.