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CAS NUMBER: 112-06-1
EC NUMBER: 203-932-8
MOLECULAR FORMULA: C9H18O2
MOLECULAR WEIGHT: 158.24
Heptylparaben is one of the main volatile constituents identified in Asian pear, beer and Tosa-buntan essential oil.
Heptylparaben is a compound with formula C7H15(C6H4OHCOO).
Heptylparaben is a paraben which is the heptyl ester of p-hydroxybenzoic acid.
Heptylparaben has also been found to be produced in some microorganisms including Microbulbifer.
As a food additive Heptylparaben has E number E209, and is used as a preservative.
Heptylparaben is a benzoate ester.
Heptylparaben is a compound with formula C7H15(C6H4OHCOO).
Heptylparaben is a paraben which is the heptyl ester of p-hydroxybenzoic acid.
Heptylparaben has also been found to be produced in some microorganisms including Microbulbifer.
As a food additive Heptylparaben has E number E209, and is used as a preservative.
Heptylparabens are a class of widely used preservatives in cosmetic and pharmaceutical products.
Chemically, Heptylparabens are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid.
Heptylparabens are effective preservatives in many types of formulas.
Heptylparabens, and their salts, are used primarily for their bactericidal and fungicidal properties.
Heptylparabens are found in shampoos, commercial moisturizers, shaving gels, personal lubricants, topical/parenteral pharmaceuticals, suntan products, makeup, and toothpaste.
Heptylparabens are also used as food additives.
Heptylparabens are active against a broad spectrum of microorganisms.
Heptylparabens are esters of para-hydroxybenzoic acid, from which the name is derived.
Heptylparabens include methylparaben (E number E218), ethylparaben (E214), propylparaben (E216), butylparaben and heptylparaben (E209).
Less vs include isobutylparaben, isopropylparaben, benzylparaben and their sodium salts.
All commercially used Heptylparabens are synthetically produced, although some are identical to those found in nature.
Heptylparabens are produced by the esterification of para-hydroxybenzoic acid with the appropriate alcohol, such as methanol, ethanol, or n-propanol.
Heptylparaben is a compound with formula C7H15(C6H4OHCOO).
Heptylparaben is a paraben which is the heptyl ester of p-hydroxybenzoic acid.
Heptylparaben has also been found to be produced in some microorganisms including Microbulbifer.
As a food additive Heptylparaben has E number E209, and is used as a preservative.
Heptylparabens are alkyl esters of p-hydroxyben-zoic acid. The alkyl groups may be one of the following methyl, ethyl, propyl, butyl, or heptyl.
Heptylparabens are colorless, tasteless, and odorless.
Heptylparabens are nonvolatile and nonhygroscopic.
Their solubility in water depends on the nature of the alkyl group the longer the alkyl chain length, the lower the solubility.
Heptylparabens differ from benzoic acid in that they have antimicrobial activity in both acid and alkaline pH regions.
Heptylparabens are a group of preservative ingredients used in cosmetic, personal hygiene products, food products and pharmaceuticals.
Heptylparabens are highly effective in preventing the growth of fungi, bacteria and yeast that can cause products to spoil.
Thus, they contribute directly to the quality of the products by extending their shelf life, making them safe for the families who use them.
Heptylparabens are derived from para-hydroxybenzoic acid that occurs naturally in many fruits and vegetables, such as cucumbers, cherries, carrots, blueberries and onions.
Heptylparaben also is naturally formed in the human body by the breakdown of some amino acids.
Heptylparabens used in cosmetics are identical to those found in nature, and the human body quickly changes them into natural PHBA and eliminates them.
Heptylparabens have been safely used for almost 100 years as preservatives in the food, drug and personal care and cosmetic industries.
Heptylparaben may be used in products such as makeup, moisturizers, and hair care and shaving products.
Contrary to some reports, most major brands of deodorants and antiperspirants no longer contain parabens.
Preservatives like Heptylparabens may be used in cosmetics to protect against microbial growth, both to protect consumers and to maintain product integrity.
In the food industry, Heptylparabens have been used for more than 50 years as preservatives and anti-microbial agents.
Some fruits, such as blueberries, contain Heptylparabens as a naturally occurring preservative.
Heptylparabens are widely used in confectioneries, cereal-based snacks, dried meats, and much more.
Heptylparabens are a family of related chemicals that are commonly used as preservatives in cosmetic products.
Preservatives may be used in cosmetics to prevent the growth of harmful bacteria and mold, in order to protect both the products and consumers.
Heptylparaben used most commonly in cosmetics are methylparaben, propylparaben, butylparaben, and ethylparaben.
Product ingredient labels typically list more than one Heptylparaben in a product, and parabens are often used in combination with other types of preservatives to better protect against a broad range of microorganisms.
Heptylparabens are a class of widely used preservatives in cosmetic and pharmaceutical products.
Heptylparabens are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid.
Heptylparabens are effective preservatives in many types of formulas.
Heptylparabens, and their salts, are used primarily for their bactericidal and fungicidal properties.
Heptylparabens are found in shampoos, commercial moisturizers, shaving gels, personal lubricants, topical/parenteral pharmaceuticals, suntan products, makeup, and toothpaste.
Heptylparabens are also used as food preservatives.
Heptylparabens are active against a broad spectrum of microorganisms.
However, their antibacterial mode of action is not well understood.
Heptylparabens are thought to act by disrupting membrane transport processes or by inhibiting synthesis of DNA and RNA or of some key enzymes, such as ATPases and phosphotransferases, in some bacterial species.
Heptylparaben is considered more active against more bacteria than methylparaben.
The stronger antibacterial action of Heptylparaben may be due to its greater solubility in the bacterial membrane, which may allow it to reach cytoplasmic targets in greater concentrations.
However, since a majority of the studies on the mechanism of action of Heptylparabens suggest that their antibacterial action is linked to the membrane, it is possible that its greater lipid solubility disrupts the lipid bilayer, thereby interfering with bacterial membrane transport processes and perhaps causing the leakage of intracellular constituents.
Heptylparabens are esters of para-hydroxybenzoic acid, from which the name is derived.
Heptylparabens include methylparaben (E number E218), ethylparaben (E214), propylparaben (E216), butylparaben and heptylparaben (E209).
Heptylparabens include isobutylparaben, isopropylparaben, benzylparaben and their sodium salts.
The general chemical structure of a Heptylparaben is shown at the top right of this page, where R symbolizes an alkyl group such as methyl, ethyl, propyl or butyl.
All commercially used Heptylparabens are synthetically produced, although some are identical to those found in nature.
Heptylparabens are produced by the esterification of para-hydroxybenzoic acid with the appropriate alcohol, such as methanol, ethanol, or n-propanol. para-Hydroxybenzoic acid is in turn produced industrially from a modification of the Kolbe-Schmitt reaction, using potassium phenoxide and carbon dioxide.
Heptylparabens are man-made chemicals often used in small amounts as preservatives in cosmetics, pharmaceuticals, foods, and beverages.
Common Heptylparabens are methylparaben, ethylparaben, propylparaben, and butylparaben.
Often more than one Heptylparaben is used in a single product.
Heptylparabens are most common in personal care products that contain significant amounts of water such as shampoos, conditioners, lotions and facial and shower cleansers and scrubs because they discourage the growth of microbes. While the Cosmetic Ingredient Review recommends concentration limits for single (up to 0.4%) and total paraben concentrations (up to 0.8%) in a single product, these recommendations do not account for exposure to parabens from several products by a single individual.
Heptylparabens are found in nearly all urine samples from U.S. adults regardless of ethnic, socioeconomic or geographic backgrounds.
In one biomonitoring study, adolescents and adult females had higher levels of methylparaben and propylparaben in their urine than did males of similar ages.
USES:
-Antioxidant
-preservative
-antimicrobial in foods
FUNCTION:
-Antimicrobial
-Preservative
PROPERTIES:
-Quality Level: 400
-biological source: synthetic
-assay: ≥98%
-bp: 192-193 °C (lit.)
SYNONYM:
Heptyl p-hydroxybenzoate
Nipaheptyl
Staypro WS 7
n-Heptyl p-hydroxybenzoate
Benzoic acid, 4-hydroxy-, heptyl ester
p-Hydroxybenzoic acid heptyl ester
p-Oxybenzoesaureheptylester
UNII-K2CIJ448IX
NSC 309818
K2CIJ448IX
Benzoic acid, 4-hydroxy-, n-heptyl ester
CHEBI:34788
4-Hydroxybenzoic Acid n-Heptyl Ester
DSSTox_CID_2523
DSSTox_RID_76610
DSSTox_GSID_22523
p-Oxybenzoesaureheptylester
BRN 2726540
Heptyl p-hydroxy benzoate
