HEXYLENE GLYCOL

Synonyms:
1,1,3-TRIMETHYLTRIMETHYLENEDIOL; 2,4-DIHYDROXY 2-METHYL PENTANE; 2,4-PENTANEDIOL, 2-METHYL-; 2-METHYL 2,4-PENTANDIOL; 2-METHYL PENTANE-2,4-DIOL; 2-METHYL-2,4-PENTANEDIOL; 4-METHYL 2,4-PENTANEDIOL; ALPHA, ALPHA, ALPHA'-TRIMETHYL TRIMETHYLENEGLYCOL; Hexylene glycol; Hexylène glycol; METHYL-2 PENTANEDIOL-2,4; METHYL-4; PENTANEDIOL-2,4; TRIMETHYL-1,1,3 TRIMETHYLENEDIOL; Hexylene glycol; HEXYLENEGLYCOL; Hexyleneglycol; 4-METHYL 2,4-PENTANEDIOL; ALPHA, ALPHA, ALPHA'-TRIMETHYL TRIMETHYLENEGLYCOL; Hexylene glycol; Hexylène glycol; METHYL-2 PENTANEDIOL-2,4; METHYL-4; PENTANEDIOL-2,4; TRIMETHYL-1,1,3 TRIMETHYLENEDIOL; Hexylene glycol; HEXYLENEGLYCOL; Hexyleneglycol; heksilen glikol; hexilen glikol; heksilen glicol; HEXYLENE GLYCOL; HEXYLENEGLYCOLE; 1,1,3-trımethyltrımethylenedıol; 2,4-dıhydroxy 2-methyl pentane; 2,4-pentanedıol, 2-methyl-; 2-methyl 2,4-pentandıol; 2-methyl pentane-2,4-dıol; 2-methyl-2,4-pentanedıol; 4-methyl 2,4-pentanedıol; alpha, alpha, alpha'-trımethyl trımethyleneglycol; hexylene glycol; hexylène glycol; methyl-2 pentanedıol-2,4; methyl-4; pentanedıol-2,4; trımethyl-1,1,3 trımethylenedıol; hexylene glycol; hexyleneglycol; hexyleneglycol; heksilen glikol; hexilen glikol; heksilen glicol; hexylene glycol; hexyleneglycole; 1,1,3-Trımethyltrımethylenedıol; 2,4-Dıhydroxy 2-Methyl Pentane; 2,4-Pentanedıol, 2-Methyl-; 2-Methyl 2,4-Pentandıol; Hexylene glycol,99%;AC1L1PQO,AC1Q2BUQ,2methyl-2,4-pentanediol;Hexylene glycol, >=99%;Hexylene glycol, 99.5%;ACMC-1BS78;SCHEMBL19379;2,4-Pentanediol,2-methyl-;2-Methyl-pentane-2,4-diol;1,3-Trimethyltrimethylenediol,4-01-00-02565 (Beilstein Handbook; Reference); KSC489M3B;CHEMBL2104293;DTXSID5021885;CTK3I9630;NSC8098;(?)-2-Methyl-2,4-pentanediol;MolPort-003-925-933;SVTBMSDMJJWYQN-UHFFFAOYSA-N;HMS3264E19;HY-B0903;NSC-8098;Hexylene glycol, analytical standard;Tox21_201975;Tox21_302818;ANW-15793;MFCD00004547;AKOS015901459;CCG-213719;MCULE-5281049691;RTR-032435;TRA0072741;WLN: QY1 & 1XQ1 & 1;NCGC00249143-01;NCGC00256494-01;NCGC00259524-01;AC-13749;AN-22478;BC206685,Hexylene glycol, BioXtra, >=99% (GC),KB-68983;OR014662;LS-101663;R-(-)-2-METHYL-2,4-PENTANEDIOL;TR-032435;FT-0613069;Hexylene glycol, puriss.,>=99.0% (GC);M0384;ST51047360;.alpha.,.alpha.'-Trimethyltrimethylene glycol;Hexylene glycol, BioUltra, >=99.0% (GC);D04439;41994-80-3 (unspecified titanium(4+) salt);AB01563179_01;J-640306;J-660006;W-108748;I14-13847;Hexylene glycol, United States Pharmacopeia (USP) Reference Standard;( inverted exclamation markA)-2-(1/4)x>>u-2,4-Ii paragraph signthorn (1/4);Hexylene glycol, PharmaGrade, USP/NF, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production;HG; 1,1,3-trimethyl-triethylenediol; diacetone glycol ;methylamilene glycol; 2,4-dihydroxy-2-methyl-pentane; 2,4-pentanediol, 2-methyl; 2-methylpentane-2,4-diol ;2,4-dihydroxy-2-methyl pentane;2,4-dihydroxy-2-methylpentane;1,3-dimethyl-3-hydroxybutanol;diolane;hexylen glycol;(±)-hexylene glycol;isol;2-methyl pentane-2,4-diol;2-methyl-2,4-pentandiol;4-methyl-2,4-pentane diol;2-methyl-2,4-pentanediol;2-methylpentane-2,4-diol;2,4-pentanediol, 2-methyl-;pinakon;1,1,3-trimethyl trimethylene diol;alpha,alpha,alpha'-    ;trimethyl trimethylene glycol;1,1,3-trimethyl-1,3-propanediol;1,3,3-trimethyl-1,3-propanediol;1,1,3-trimethyltrimethylenediol;2-Methyl-2,4-pentanediol ;2,4-Dihydroxy-2-methylpentane ;2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, 2-Methylpentane-2,4-diol;CAS 107-41-5 ;2-methyl pentane-2,4-diol;2,4-dihydroxy-2-methyl pentane ;2-methyl 2,4 pentanediol;4-methyl 2,4 pentanediol;2-methyl-pentane-2,4-diol;1,1,3-trimethyl trimethylene glycol ;1,1,3-trimethyl trimethylenediol;trimethyltrimethylene ;glycol Diolane ;2-Methyl-2,4-pentanediol; Diolane; Hexylene glycol;;2-Methylpentane-2,4-diol; 2-Metilpentano-2,4-diol; 2-Méthylpentane-2,4-diol; (+-)-2-Methyl-2,4-pentanediol; 1,1,3-Trimethyltrimethylenediol; 2,4-Dihydroxy-2-methylpentane; 4-Methyl-2,4-pentanediol; alpha,alpha,alpha'-Trimethyltrimethylene glycol;;4-Methyl-2,4-pentanediol; Pinakon ;2-Methylpentane-2,4-Diol; 4-Methyl-2,4-pentanediol;; 2,4-Pentanediol, 2-methyl-; 2-Methylpentane-2,4-diol;2,4-DIHYDROXY-2-METHYLPENTANE;HEXYLENE GLYCOL;2-METHYL-2,4-PENTANEDIOL;4-METHYL-2,4-PENTANEDIOL;2-METHYLPENTANE-2,4-DIOL;butyl diglycol;butyl glycol;dpm (methoxy propoxy propanol);monoethanolamine ...;pm (1-methoxy 2-propanol);HEXYLENE GLYCOL;2-METHYL-2,4-PENTANEDIOL;2-METHYLPENTANEDIOL-2,4;2,4-PENTANEDIOL, 2-METHYL-;ALPHA,ALPHA,ALPHA'-TRIMETHYLTRIMETHYLENE GLYCOL;1,1,3-TRIMETHYLTRIMETHYLENEDIOL;2,4-Pentanediol, 2-methyl-, diacetate [ACD/Index Name];216-667-8 [EINECS];2-Methyl-2,4-pentandiyl-diacetat [German] [ACD/IUPAC Name];2-Methyl-2,4-pentanediyl diacetate [ACD/IUPAC Name];2-Methylpentane-2,4-diyl diacetate;Diacétate de 2-méthyl-2,4-pentanediyle [French] [ACD/IUPAC Name];Hexylene glycol diacetate;1637-24-7 [RN];2,4-PENTANEDIOL,2-METHYL-,DIACETATE;2-Methyl-2,4-pentanediol diacetate;3-02-00-00321 [Beilstein];4-(ACETYLOXY)-2-METHYLPENTAN-2-YL ACETATE;Acetic acid, 2-methyl-2, 4-pentanediol diester;Acetic acid, 2-methyl-2,4-pentanediol diester;Acetic acid, hexylene glycol;WLN: 1VOY1&1X1&1&OV1;Hexylene Glycol; 2,4-Pentanediol, 2-methyl-; Diolane; Isol; 1,1,3-Trimethyltrimethylenediol; 2-Methyl-2,4-pentandiol; 2-Methyl-2,4-pentanediol; 2,4-Dihydroxy-2-methylpentane; 4-Methyl-2,4-pentanediol; 2-Methyl pentane-2,4-diol; 2-Methylpentan-2,4-diol; Pinakon; 4-Methyl-2,4-pentanediole;2,4-Pentanediol,2-Methyl-;2-Methyl-2,4-Pentanediol;2,4-Pentanediol, 2-methyl-;1,1,3-trimethyl-1,3-propanediol ;1,1,3-Trimethyltrimethylenediol;1,3,3-trimethyl-1,3-propanediol;1,3-dimethyl-3-hydroxybutanol;2,4-Dihydroxy-2-methylpentane;2-Methyl pentane-2,4-diol;2-Methyl-2,4-pentandiol;2-Methyl-2,4-pentanediol;4-Methyl-2,4-pentanediol;?,?,?'-trimethyltrimethylene glycol;Hexylene glycol;MPD;Hexylene Glycol;«alpha»,«alpha»,«alpha»'-Trimethyltrimethylene glycol;Diolane;Isol;1,1,3-Trimethyltrimethylenediol;2-Methyl-2,4-pentandiol;2-Methyl-2,4-pentanediol;2,4-Dihydroxy-2-methylpentane;4-Methyl-2,4-pentanediol;2-Methyl pentane-2,4-diol;2-Methylpentan-2,4-diol;Pinakon;4-Methyl-2,4-pentanediole;«alpha»,«alpha»,«alpha»-Trimethyltrimethyleneglycol; 1,2-Hexanediol;5,6- dihydroxyhexane;HEXANEDIOL-1,2; DL-Hexan-1,2-diol; HYDROLITE® 6; 2-Methyl-2,4-Pentanediol; 2,4-Pentanediol;2-Methyl-; 2,4-Pentanediol, 2-methyl-; 2-Methyl-2,4-pentanediol; (+-)-2-Methyl-2,4-pentanediol; 1,1,3-Trimethyltrimethylenediol; 2,4-Dihydroxy-2-methylpentane; 2-Methylpentane-2,4-diol; 4-Methyl-2,4-pentanediol; 1,1,3-trimethyl trimethylene glycol; 1,1,3-trimethyltrimethylenediol; trimethyltrimethylene glycol; Diolane; Isol; Pinakon; HexG);2-Methylpentane-2,4-diol ;(US EPA PC Code ) , 068601 (US EPA PC Code Text ) , 107-41-5 (CAS number) , 107415 , 107415 (CAS number without hyphens) , 1254 (CA DPR Chem Code) ) , 2-Methyl-2,4-pentanediol , Hexilenglicol , Hexylene glycol , HEXYLENE GLYCOL (CA DPR Chem Code Text ) , Hexyleneglycol;2-methyl-2,4-pentanediol;2­methyl­2,4­pentanediol? 2,4­pentanediol, 2­methyl­ ;2-Methyl-2,4-pentanediol;2,4-Dihydroxy-2-methylpentane;2,4-Pentanediol,2-methyl-,(±)-.(±)-2-Methyl-2,4-pentanediol [107-41-5];MPD, 2-Metylopentano-2,4-Diol, 2,4-Dihydroxy-2-Methylpentane, 1,1,3 Trimethyltrimethylenediol;Hexylene Glycol; 2,4-Pentanediol, 2-methyl-; ?,?,?'-Trimethyltrimethylene glycol; Diolane; Isol; 1,1,3-Trimethyltrimethylenediol; 2-Methyl-2,4-pentandiol; 2,4-Dihydroxy-2-methylpentane; 4-Methyl-2,4-pentanediol; 2-Methyl pentane-2,4-diol; 2-Methylpentan-2,4-diol; Pinakon; 4-Methyl-2,4-pentanediole; (.+/-.)-2-Methyl-2,4-pentanediol; NSC 8098; Isophthalic acid; Hexylene;2,4-Dihydroxy-2-methylpentan; 2-Methylpentan-2,4-diol; Hexylenglykol;MPD;Isol;4-HPD; Diolane; Pinadon; Pinakon; HEXASOL; Hexalene glycol; HEXYLENE GLYCOL;dihydroxyhexane;2-Methyl-2,4-pentanediol; HGL; 2-methyl pentane-2,4-diol, pinakon, diolane,MPD;Hexylenglycol; 2-Methylpentan-2,4-diol; Hexylenglykol; 2-Methyl-2,4-Pentandiol; 1,2-Hexanedio;2-Methylpentan-2,4-diol; Hexylenglykol; 2-Methyl-2,4-Pentandiol; 1,2-Hexanediol; 2-methylpentane-2,4-diol; heksilen glikol; heksılen glıkol; heksilenglikol; heksılenglıkol; HEKSİLEN GLİKOL; HEKSILEN GLIKOL; HEKSİLENGLİKOL; HEKSILENGLIKOL;HEXYLENE GLYCOL;HEXYLENEGLYCOL;hexylene glycol;hexyleneglycol;hegzilen glikol;hegzilenglikol;heksilenglikol; heksilen glikol; 2-methylpentane-2,4-diol; HEKZYLENE; GLYCOL; hekzylene; glycole; heksilen; gilikol; hekzilen; glikol; eksilengilikol; C6H14O2; CH3CHOHCH2C(OH)(CH3)2; 1,1,3-TRIMETHYLTRIMETHYLENEDIOL; 2,4-DIHYDROXY-2-METHYLPENTANE; 2,4-PENTANEDIOL, 2-METHYL-; 2,4PENTANEDIOL, 2METHYL; 2-METHYL- 2,4-PENTANEDIOL; 2-METHYL-2,4-PENTANDIOL; 2-ME(±)-2-Methyl-2,4-pentanediol, MPD; THYL-2,4-PENTANEDIOL; 2-METHYLPENTANE-2,4-DIOL; HEXYLENE GYCOL; MPD; 2,4-DIHYDROXY-2-METHYLPENTANE; 2,4-DIHYDROXY-2-METHYLPENTANE; HEXYLENE GLYCOL; 2-METHYL-2,4-PENTANEDIOL; 4-METHYL-2,4-PENTANEDIOL; 2-METHYLPENTANE-2,4-DIOL; Hexylene glycol (107-41-5); (2-Methyl-2,4-Pentanediol); Hexylene Glycol pure, 99%; MPD; Isol; 4-MPD; Diolane; Pinadon; Pinakon; HEXASOL; Hexalene glycol; HEXYLENE GLYCOL; dihydroxyhexane; CBNumber:CB5353705; NIST Chemistry Reference; 2,4-Pentanediol, 2-methyl-(107-41-5); 2-Methylpentane-2,4-diol >99.0%(GC); (±)-2-Methyl-2,4-pentanediol, 98%; 2,4-Pentanediol; 2-Methyl; 2-Methyl-2,4-Pentanediol; 2,4-Pentanediol; 2-methyl-; (2,4-dihydroxy-2-methylpentane; 2,4-pentanediol; 2-methyl; 2-methylpentane-2,4-diol; 4-methyl-2,4-pentanediol; alpha,alpha,alpha; trimethyltrimethylene glycol; diolane; hexylene glycol; isol; pinakon; 2-Methylpentane-2,4-Diol; 4-Methyl-2,4-pentanediol; 2,4-Pentanediol, 2-methyl-; 2-Methylpentane-2,4-diol; Hexylenglycol; 2-Methylpentan-2,4-diol; Hexylenglykol; 2-Methyl-2,4-Pentandiol; 1,2-Hexanediol; 2-methyl-2, 4-pentanediol; 4-methyl-2, 4-pentanediol; a,a,a'-trimethyltrimethyleneglycol; Hexylene Glycol;«alpha»,«alpha»,«alpha»'-Trimethyltrimethylene glycol;Diolane;Isol;1,1,3-Trimethyltrimethylenediol;2-Methyl-2,4-pentandiol;2-Methyl-2,4-pentanediol;2,4-Dihydroxy-2-methylpentane;4-Methyl-2,4-pentanediol;2-Methyl pentane-2,4-diol;2-Methylpentan-2,4-diol;Pinakon;4-Methyl-2,4-pentanediole;«alpha»,«alpha»,«alpha»-Trimethyltrimethyleneglycol; 2-Methyl-2,4-pentanediol; Diolane; Hexylene glycol; 2-Methylpentane-2,4-diol; 2-Metilpentano-2,4-diol; 2-Méthylpentane-2,4-diol; (+-)-2-Methyl-2,4-pentanediol; 1,1,3-Trimethyltrimethylenediol; 2,4-Dihydroxy-2-methylpentane; 4-Methyl-2,4-pentanediol; alpha,alpha,alpha'-Trimethyltrimethylene glycol; InChI=1S/C6H14O2/c1-5(7)4-6(2,3)8/h5,7-8H,4H2,1-3H3/t5-/m0/s1; SVTBMSDMJJWYQN-YFKPBYRVSA-N; 2,4-Pentanediol, 2-methyl-; α,α,α'-Trimethyltrimethylene glycol; Diolane; Isol; 1,1,3-Trimethyltrimethylenediol; 2-Methyl-2,4-pentandiol; 2-Methyl-2,4-pentanediol; 2,4-Dihydroxy-2-methylpentane; 4-Methyl-2,4-pentanediol; 2-Methyl pentane-2,4-diol; 2-Methylpentan-2,4-diol; Pinakon; 4-Methyl-2,4-pentanediole; (.+/-.)-2-Methyl-2,4-pentanediol; NSC 8098; Isophthalic acid; Hexylène Glycol; Methyl-2 Pentanedıol-2,4; Methyl-4; Pentanedıol-2,4; Trımethyl-1,1,3 Trımethylenedıol;  2-Methyl Pentane-2,4-Dıol; 2-Methyl-2,4-Pentanedıol; 4-Methyl 2,4-Pentanedıol; Alpha, Alpha, Alpha'-Trımethyl Trımethyleneglycol; Hexylene Glycol; Hexylène Glycol; Methyl-2 Pentanedıol-2,4; Methyl-4; Pentanedıol-2,4; Trımethyl-1,1,3 Trımethylenedıol; Hexylene Glycol; Hexyleneglycol; Hexyleneglycol; Heksilen Glikol; Hexilen Glikol; Heksilen Glicol; Hexylene Glycol; Hexyleneglycole

HEXYLENE GLYCOL
Hexylene Glycol

Hexylene Glycol
Hexylene Glycol.png
Names
Preferred IUPAC name
2-Methylpentane-2,4-diol
Other names
Hexylene Glycol
Hexylene glycol
Diolane
1,1,3-Trimethyltrimethylenediol
2,4-Dihydroxy-2-methylpentane
Isol
Identifiers
CAS Number    
107-41-5 ☑
99210-90-9 (R) ☒
99210-91-0 (S) ☒
3D model (JSmol)    
Interactive image
Abbreviations    MPD
ChEBI    
CHEBI:62995 ☒
ChEMBL    
ChEMBL2104293 ☒
ChemSpider    
7582 ☑
ECHA InfoCard    100.003.173
PubChem CID    
7870
UNII    
KEH0A3F75J ☑
CompTox Dashboard (EPA)    
DTXSID5021885 
InChI[show]
SMILES[show]
Properties
Chemical formula    C6H14O2
Molar mass    118.176 g·mol−1
Appearance    colourless liquid
Odor    mild, sweetish[1]
Density    0.92 g/mL
Melting point    −40 °C (−40 °F; 233 K)
Boiling point    197 °C (387 °F; 470 K)
Solubility in water    miscible[1]
Vapor pressure    0.05 mmHg (20°C)[1]
Hazards
Flash point    98.3 °C (208.9 °F; 371.4 K) [2]
Explosive limits    1.3%-7.4%[1]
NIOSH (US health exposure limits):
PEL (Permissible)    none[1]
REL (Recommended)    C 25 ppm (125 mg/m3)[1]
IDLH (Immediate danger)    N.D.[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Hexylene Glycol (MPD) is an organic compound with the formula (CH3)2C(OH)CH2CH(OH)CH3. This colourless liquid is a chiral diol. It is produced industrially from diacetone alcohol by hydrogenation.[3] Total European and USA production was 15000 tonnes in 2000.[4]

Hexylene Glycol exists as two enantiomers, (4R)-(-) and (4S)-(+). In the Protein Data Bank, the 3-letter code "MPD" refers to the (S)-(-) enantiomer, while "MRD" is used to refer to the (R)-(+) version. Commercial products labeled "MPD" are usually the racemate,[5] also sold as and referred to as "hexylene glycol".[6][7]

Uses
Hexylene Glycol exhibits both surfactant and emulsion-stabilizing properties. Its relatively high viscosity and low volatility are advantageous in coatings, cleansers, cosmetics, solvents, and hydraulic fluids.[8] Although it is an irritant at higher concentrations, it is sometimes used in skin care, hair care, soap, and eye cosmetic products at concentrations ranging from 0.1% - 25%.[9][10]

It's is biodegradable and unlikely to accumulate in the environment.[11]

Laboratory uses
In the laboratory it is a common precipitant and cryoprotectant in protein crystallography.[12] Since hexylene glycol is compatible with polar and nonpolar molecules, it competes with the solvent in a crystallography experiment causing the protein to precipitate.[13] Hexylene glycol is so effective in protein crystallography because its amphiphilic nature and small, flexible structure allows it to bind to many different locations on a protein secondary structure including alpha helices and beta sheets.[14] When hexylene glycol binds to these different locations, water is removed and the protein crystals anneal, which prevents ice formation during cryocrystallography techniques.[15] Incorporation of hexylene glycol into solution has been known to improve the resolution of X-ray diffraction making protein structures easily identifiable.[16] Additionally hexylene glycol is not a strong denaturing agent and thus does not significantly alter the structure of a protein during the crystallography procedure.[14]

Like related diols, it forms borate esters.

HEXYLENE GLYCOL
HEXYLENE GLYCOL is classified as :
Emulsifying
Skin conditioning
Solvent
Surfactant
Perfuming
CAS Number    107-41-5
EINECS/ELINCS No:    203-489-0
COSING REF No:    34283
INN Name:    hexylene glycol
Chem/IUPAC Name:    2-Methylpentane-2,4-diol

Product overview
Hexylene Glycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions. It has a low evaporation rate and it is completely miscible with water.

It is mainly used as a solvent or coupling agent. It is a potential substitute for glycol ethers. It is also an effective shrinkage reduction admixture or SRA for concrete and mortar. Hexylene glycol can also be used as a building block in chemical synthesis.

Hexylene glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.

Hexylene Glycol

What Is It?
Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are clear, practically colorless, liquids. In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.

Why is it used in cosmetics and personal care products?
Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are used as solvents and viscosity decreasing agents in cosmtics and personal care products.

Scientific Facts: 
Butylene Glycol, or 1,3-Butanediol, dissolves most essential oils and synthetic flavoring substances. Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are glycols or glycol ethers. Glycols are a class of alcohols that contain two hydroxyl groups which are also called a diols.

Physical Description

HEXYLENE GLYCOL is an oily colorless liquid with a mild sweet odor. Floats and mixes slowly with water.Boiling Point of Hexylene Glycol 387° F at 760 mm Hg, Flash Point of Hexylene Glycol, 200° F. Density of Hexylene Glycol, 0.923 at 68° F. Hexylene glycol is a small molecular weight surfactant. Fragrance Function(s) of Hexylene glycol:Ingredient; Solvent; Viscosity Decreasing Agent; EMULSIFYING; PERFUMING; SKIN CONDITIONING; SURFACTANT. Hexylene Glycol is a solvent and viscosity agent used in many skin care products. Hexylene Glycol is used to thin out heavy compositions and create a thinner, more spreadable product.Hexylene glycol is a water-white, moderately hygroscopic glycol. Hexylene Glycol hasexceptional solvency for a variety of materials and is miscible with aliphatic andaromatic hydrocarbons as well as with polar substances such as water, fattyacids, and alcohols. Hexylene Glycol (MPD) is an organic compound with the formula (CH3)2C(OH)CH2CH(OH)CH3. Hexylene Glycol is a chiral diol. Hexylene Glycol is produced industrially from diacetone alcohol by hydrogenation. Total European and USA production was 15000 tonnes in 2000. 2-Methyl-2,4-pentanediol exists as two enantiomers, (4R)-(-) and (4S)-(+). In the Protein Data Bank, the 3-letter code "MPD" refers to the (S)-(-) enantiomer, while "MRD" is used to refer to the (R)-(+) version. Commercial products labeled "MPD" are usually the racemate, also sold as and referred to as "hexylene glycol".

Applications of Hexylene Glycol
Hexylene glycol is mainly used in the coating industry but also in washing and cleaning products, lubricants, metal working fluids, road and construction applications and in agrochemicals. Hexylene glycol's using areas ;hydraulic fluid, printing ink solvent, fuel & lubricant additive? defoamer.Crystallization grade (+/-)-2-Methyl-2,4-pentanediol for formulating screens or for optimization.

General Statement of Hexylene Glycol
Hexylene glycol is a colourless liquid organic compound with a characteristic sweet odour. It is viscous and miscible with the most common organic solvents, fatty acids and water.Hexylene glycol occurs as a component in a large number of products for industrial, professional and consumer use. There is a potential for occupational and consumer exposure through inhalation and skin contact.The pure substance is an eye and skin irritant. It is only professionally or industrially used and must be handled under stringent safety conditions in accordance with the risk management measures to keep the exposure as minimum as possible to preserve human health and environment.Hexylene glycol is formulated in suitable concentrations for consumer applications, according to appropriate regulations, to ensure safe use of the final product in the conditions of use written on the product packaging. Hexylene Glycol is a clear, colourless liquid with a characteristic odour. It is fully miscible in water and has the chemical formula C6H14O2. Hexylene glycol is a compound that appears in a large number of products that are used commercially and industrial. The single largest user of hexylene glycol is the industrial coatings industry which uses approximately 45% of the HGL produced world-wide. It is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings. It is also a component in both oil and water- based paints, and in paint strippers.

Uses and applications of Hexylene Glycol

Hexylene glycol is a low-evaporating solvent with complete water solubility. It is mainly used as a surfactant or emulsifying agent.Hexylene glycol is widely used in the coating industry as a component for lacquers, varnishes, printing inks and both oil and water-based paints.It is also used as an inert ingredient in pesticide formulations, as a solvent in dyes preparations, as a coupling agent for hydraulic fluids in the automotive industry, as a wetting agent, as an anti-caking agent for cement and siliceous derived industries, as a setting agent in the manufacture of textiles, and as a component in cosmetics, industrial and household cleaners, and antifreeze solutions.Hexylene glycol is also used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. Hexylene Glycol is a humectant or humidifying and delivery ingredient used in cosmetics. When used in small amounts to keep products from melting in high heat or freezing when it is cold. It also helps active ingredients penetrate the skin. It is supplied as a water white liquid and is readily water-soluble. It is used in cosmetic formulations such as creams and lotions at typical use levels of 1-5%.Hexylene glycol is used as a coupling agent in the manufacture of hydraulic fluids, industrial cleaning compounds, soluble oils and dry cleaning soaps. In latex paints, hexylene glycol is a valuable and versatile additive; it aids coalescence, promotes levelling and smoothness of films, enhances film integrity and preserves freeze-thaw resistance. Solvent uses for hexylene glycol include the preparation of dyes, and synthetic resin-base- flash-dry and steamset inks. It also functions as a moistening and softening agent for composition cork, casein, leather, paper and textile fibres, and as a wetting or dispersing agent in polishes and cleaners. Other applications for hexylene glycol include its use as an ingredient in grinding and extrusion aids and as a solvent palsticiser in surface coatings.

This clear, colorless liquid is widely used as an industrial coating solvent.HG exposure is possible in both industrial and consumer applications. Occupational exposure limits have been established to control the allowable amount of exposure in workplace settings.Consumer exposure, generally infrequent and short in duration, is also highly dependent upon the conditions under which hexylene glycol is used. See Health Information.Hexylene glycol does not cause adverse health or environmental effects at levels typically found in the workplace or in the environment. Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are clear, practically colorless, liquids. In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.

GENERAL DESCRIPTION

The chemical structure of polymethylated hydrocarbon chain have limited water solubility, while alcohol groups introduce the improved hydrophilic solubility performance. Hexylene glycol can provide the proper balance of target properties when solvent-based solvents are formulated for desired viscosity, flowing and leveling, and curing rate and can be used as coupling agents in waterborne coatings. Hexylene Glycol is used as a coupling agent in the manufacture of hydraulic fluids, cleaner compounds. The hydroxyl group will undergo reaction with aldehydes (or ketones) to produce hemiacetals (or acetals), with epoxides to produce polyether alcohols, with halogenating agents to produce alkoxy alkyl halides, with carboxylic acid compounds or inorganic acids to produce a number of esters. Hexylene Glycol is used as Diol or solvent in urethane manufacturing, As an effective insect repellent, Emollient agent for cosmetic creams and lotions, Coupling agent for shampoos, and liquid cleansing creams, Lubricant for textile spinning and Solvency component for printing inks.

Hexylene Glycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions. It has a low evaporation rate and it is completely miscible with water. Hexylene Glycol is mainly used as a solvent or coupling agent. Hexylene Glycol is a potential substitute for glycol ethers. Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar. Hexylene glycol can also be used as a building block in chemical synthesis. Hexylene glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather. Hexylene glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour. It is fully miscible in water and has the chemical formula C6H14O2. Hexylene glycol is a compound that appears in a large number of products that are used commercially and industrially.

Applications of Hexylene Glycol

The biggest user of hexylene glycol is the industrial coatings industry which uses approximately 45% of the world-wide production . It is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings. It is also a component in both oil and water- based paints, and in paint strippers. Hexylene glycol is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where it is both a down hole lubricant, and a grinding and extraction aid. Hexylene glycol is also employed as an antifreeze, and as a coupling agent for hydraulic fluids. It is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations. It also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes. Hexylene glycol is as used moisture creams, Aftershave products, Hair colors, Hair conditioners and Shampoos.