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IMIDAZOLIDONE

CAS Number : 120-93-4
EC  Number : 204-436-4
Molecular Formula :     C3H6N2O
Molecular Weight  :  86.09

Imidazolidinones or imidazolinones are a class of 5-membered ring heterocycles structurally related to imidazole. 
Imidazolidinones feature a saturated C3N2 backbones, except for the presence of a urea or amide functional group in the 2 or 4 positions.
The Imidazolidone are cyclic ureas. 
Imidazolidone is a polar solvent and Lewis base. 

Drugs featuring this ring system include emicerfont, imidapril, and azlocillin. 
Imidazolidone is the reagent used in permanent press clothing.
Imidazolones (also called imidazolinones) are oxo derivatives of imidazoline (dihydroimidazoles). 
Examples include imidazol-4-one-5-propionic acid, a product of the catabolism of histidine, and imazaquin, a member of the imidazolinone class of herbicide.

Application of Imidazolidone
Reactant for synthesis of:
-Chiral microporous materials from achiral precursors
-Aryl and heteroaryl N-acylureas via microwave-assisted palladium-catalyzed carbonylation
-A highly water-soluble peptide based human neutrophil elastase inhibitor
-Heterocycles by cyanoacetylation for antimicrobial use

Use and Manufacturing of Imidazolidone
Used to make high polymers, plasticizers, lacquers, adhesives, and textile and leather finishing agents; Also used as an insecticide

Industry Uses of Imidazolidone
-Fragrance
-Intermediates
-Wrinkle resisting agent

Consumer Uses of Imidazolidone
-Fragrance
-Solvent
-Wrinkle resisting agent

General Manufacturing Information    
Industry Processing Sectors
-All Other Basic Organic Chemical Manufacturing
-All Other Chemical Product and Preparation Manufacturing
-Textiles, apparel, and leather manufacturing

Specifications of Imidazolidone
CAS Min %    : 95.0
CAS Max %    : 100.0
Color             : White
Melting Point     : 131.4°C to 132.4°C
Boiling Point     : 187.0°C (10.0 Torr)
Assay Percent Range    : 95% min. (HPLC)
Infrared Spectrum    : Authentic
Beilstein       :  24,2
Packaging       :  Glass bottle
Merck Index       :  15,4955

Imidazolidone  is an organic compound that is used in the synthesis of glycol ethers. 
Imidazolidone has been shown to be a potent inhibitor of renal fibrosis in vivo and its pharmacokinetic properties have been studied in a rat model. 
Imidazolidone has also been shown to inhibit the production of proinflammatory cytokines and reduce light emission. 
Imidazolidone is a structural analog of imidazolidinones, which are known to possess antiinflammatory activity. 

Imidazolidone can be synthesized by reacting trifluoroacetic acid with an aromatic hydroxyl group and two nitrogen atoms. 
The major metabolic pathways for this compound include oxidation, reduction, hydrolysis, and conjugation with glucuronic acid. 
Imidazolidone reacts with water molecules to form hydrogen peroxide and molecular oxygen gas. 
Imidazolidone is a metabolite of ethylenethiourea (ETU), a decomposition product of the ethylenebis(dithiocarbamate) (EBDC) fungicides.

Use of Imidazolidone:
Imidazolidone is mainly used in textile, pharmaceutical industry and biological field. 
Imidazolidone can adjust plant growth adjustor, bactericide, herbicide and other.
Used as formaldehyde capture agent, fine chemicals intermediates, also used in the preparation of resin and the preparation of plasticizers, paint, adhesives, etc.

use as formaldehyde capture agent to remove formaldehyde remaining in fabrics after finishing with 2D-resin, KB resin, urea-formaldehyde resin, melamine formaldehyde resin, etc. 
Imidazolidone is also used as an intermediate for fine chemicals, used to make resins, plasticizers, paints, adhesives, etc.
Imidazolidone Used as a formaldehyde capture agent, an intermediate for fine chemicals, and also used to make resins and formulate plasticizers, spray paints, adhesives, etc.
Imidazolidone Used to synthesize chiral microporous materials prepared from achiral precursors; Used to prepare aryl and heteroaryl N-acylurea through microwave-assisted palladium-catalyzed carbonylation reaction; used to synthesize a highly water-soluble peptide based on human neutrophil elastase inhibitors; formed by cyanoacetylation reaction, used to synthesize antibacterial heterocyclic rings; used for Pd-catalyzed reaction to form C- N bonds with heteroaromatic toluene sulfonate; used to activate the oxidative amidation reaction of alkenes


FIRST AID MEASURES of Imidazolidone

General Advice :
If symptoms persist, call a physician. 

Eye Contact :
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. 
Getmedical attention. 

Skin Contact :
Wash off immediately with plenty of water for at least 15 minutes. 
If skin irritation persists,call a physician.

Ingestion :
Clean mouth with water and drink afterwards plenty of water. 
Get medical attention if symptoms occur.

Inhalation :
Remove to fresh air. 
If not breathing, give artificial respiration. 
Get medical attention if symptoms occur.

Substance identity

EC / List no.: 204-436-4
CAS no.: 120-93-4
Mol. formula: C3H6N2O

Hazard classification & labelling of Imidazolidone
Warning! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation and may cause damage to organs through prolonged or repeated exposure.

About Imidazolidone
Imidazolidone is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Imidazolidone is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of Imidazolidone
Imidazolidone is used in the following products: inks and toners.
Other release to the environment of Imidazolidone is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Article service life of Imidazolidone
Other release to the environment of Imidazolidone is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Imidazolidone can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

Widespread uses by professional workers of Imidazolidone
Imidazolidone is used in the following products: inks and toners. 
Imidazolidone is used in the following areas: printing and recorded media reproduction. 
Other release to the environment of Imidazolidone is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing of Imidazolidone
Imidazolidone is used in the following products: inks and toners.
Release to the environment of Imidazolidone can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites of Imidazolidone
Imidazolidone is used in the following products: adsorbents and inks and toners.
Imidazolidone is used in the following areas: printing and recorded media reproduction.
Release to the environment of Imidazolidone can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Manufacture of Imidazolidone
Release to the environment of Imidazolidone can occur from industrial use: manufacturing of the substance.

Synonyms:
2-imidazolidone
2-imidazolidone
1,3-Ethyleneurea2-Imidazolidinone 2-Imidazolidone2-OxoimidazolidineEthylene urea
2-Imidazolidinone
2-imidazolidinone
2-Imidazolidone
2-imidazolidone
2-imidazolidone
Ethylene Urea
imidazolidin-2-one
1,3-Ethyleneurea
2-Imidazolidinone
2-IMIDAZOLIDONE
2-Imidazolidone
2-Oxoimidazolidine
CIM-70
ETHYLENE UREA
Ethyleneurea
Ethylenharnstoff
Imidazolidinone (6CI)
SD 6073
Urea, ethylene- (7CI)
Urea, N,N'-(1,2-ethanediyl)-
120-93-4
76895-63-1
2-Imidazolidone
imidazolidin-2-one
120-93-4
2-Imidazolidinone
ETHYLENEUREA
imidazolidinone
Ethylene urea
N,N'-Ethyleneurea
2-Oxoimidazolidine
1,3-Ethyleneurea
Imidazolid-2-one
Monoethyleneurea
2-Oxomidazolidine
Urea, 1,3-ethylene-
SD 6073
2-imidazolidinon
Urea, N,N'-(1,2-ethanediyl)-
NSC 21314
CHEBI:37001
Urea,3-ethylene-
NSC-21314
WLN: T5MVMTJ
2K48456N55
Urea,N'-(1,2-ethanediyl)-
HSDB 4021
EINECS 204-436-4
imidazolidone
2-imidazolinone
AI3-22151
imidazolin-2-one
UNII-2K48456N55
Imidazoliden-2-one
2-oxo-imidazolidine
MFCD00005257
2-Imidazolidone, 96%
DSSTox_CID_602
EC 204-436-4
ETHYLENEUREA [HSDB]
DSSTox_RID_75683
DSSTox_GSID_20602
CHEMBL12034
IMIDAZOLIDINONE [INCI]
2-IMIDAZOLIDINONE [MI]
DTXSID0020602
NSC3338
NSC-3338
NSC21314
ZINC1666720
Tox21_200783
AKOS000121325
7-Benzyloxy-1H-indole-3-carboxylicacid
NCGC00248832-01
NCGC00258337-01
AS-13128
BP-21148
CAS-120-93-4
DB-021217
DB-021218
AM20080146
CS-0075560
FT-0626340
FT-0668259
I0005
EN300-21266
D71145
2-Imidazolidinon 100 microg/mL in Acetonitrile
A804620
2-Imidazolidone, PESTANAL(R), analytical standard
Q-200290
Q2813813
F0001-0335
Z104494954
106252 [Beilstein]
120-93-4 [RN]
204-436-4 [EINECS]
2-Imidazolidinon [German] [ACD/IUPAC Name]
2-Imidazolidinone [ACD/Index Name] [ACD/IUPAC Name]
2-Imidazolidinone [French] [ACD/Index Name] [ACD/IUPAC Name]
2-Imidazolidone
2K48456N55
2-OXOIMIDAZOLIDINE
ethylene urea
Imidazolidin-2-on [German]
imidazolidin-2-one
Imidazolidinone
MFCD00005257 [MDL number]
N,N'-ethyleneurea
NJ0570000
oxoimidazolidine
1,3-ethyleneurea
2-​imidazolidone
2-Hydroxypropyl-β-cyclodextrin
2-Imidazolidinon [ACD/IUPAC Name]
2-Imidazolidone|N,N'-Ethyleneurea
2-oxomidazolidine
3-oxo-4H-quinoxaline-2-carboxylic acid
4,5-didehydro-1,3-dihydroimidazol-2-one
4,5-dihydroimidazolone
BR-45753
Ethyleneurea
imidazolid-2-one
Imidazoliden-2-one
imidazolidone
imidazoline-2-one
monoethyleneurea
TL8000550
UNII:2K48456N55
UNII-2K48456N55
Urea, 1,3-ethylene-
Urea, N,N'-(1,2-ethanediyl)-
WLN: T5MVMTJ
03850_FLUKA [DBID]
45731_RIEDEL [DBID]
AI3-22151 [DBID]
AIDS018853 [DBID]
AIDS-018853 [DBID]
CHEBI:37001 [DBID]
HSDB 4021 [DBID]
I601_ALDRICH [DBID]
KN-93 [DBID]
NSC 21314 [DBID]
NSC21314 [DBID]
NSC3338 [DBID]
SD 6073 [DBID]
ZINC01666720 [DBID]


 

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