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INOSINIC ACID

Inosinic acid is used for identification in chemical databases and regulatory frameworks.
Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs.
Inosinic acid is used for laboratory and analytical use only.


CAS Number: 131-99-7 
EC Number: 205-045-1
MDL Number: MFCD00066754
E number: E630 (flavour enhancer)
IUPAC Name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate
Molecular Formula: C₁₀H₁₃N₄O₈P
Molecular Weight: ~348.21 g/mol

SYNONYMS:
Inosinic acid, IMP, inosine 5'-monophosphate, inosine monophosphate, 5'-inosinic acid, inosine-5'-monophosphate, 5'-IMP, inosine-5'-phosphate, 5'-inosine monophosphate, 5'-ribonucleotide of inosine, ribonucleotide inosine monophosphate, inosine nucleotide, Inosinic acid, IMP, inosine 5'-monophosphate, inosine monophosphate, 5'-inosinic acid, inosine-5'-monophosphate, 5'-IMP, inosine-5'-phosphate, 5'-inosine monophosphate, 5'-ribonucleotide of inosine, ribonucleotide inosine monophosphate, inosine nucleotide, inosine-5'-ribonucleotide, 5'-inosine-5'-phosphoric acid, inosine-5'-monophosphoric acid, inosine 5'-phosphate, inosine-5'-phosphoric acid, 5'-inosine phosphate, 5'-IMP disodium salt, inosine 5'-phosphoric acid sodium salt, inosine 5'-phosphate disodium salt hydrate, inosine-5'-monophosphate disodium salt, inosine monophosphoric acid, 5'-inosine monophosphoric acid, 5'-Inosinic acid, IMP, Hypoxanthine ribotide, Inosinic acid, 5'-inosinic acid, 131-99-7, 5'-inosinate, 5'-IMP, Inosine-5'-monophosphoric acid, Cytosine inosinate, TAO7US05G5, 2'-inosine-5'-monophosphate, hypoxanthosine 5'-monophosphate, INS NO.630, CHEBI:17202, DTXSID80948097, INS-630, E-630, [(2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid, Acid, Inosinic, (((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl)methoxy)phosphonic acid, ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl)methyl dihydrogen phosphate, RefChem:7619, DTXCID101376340, 205-045-1, inosine 5'-monophosphate, inosine monophosphate, IMP, inosine 5'-phosphate, 5'-inosine monophosphate, INOSINE-5'-MONOPHOSPHATE, Inosine 5'-Monophosphoric acid, BRN 0630517, Inosine 5'-(dihydrogen phosphate), CID 5280323, ribosylhypoxanthine monophosphate, [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxypurin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid, C10H13N4O8P, EINECS 205-045-1, UNII-TAO7US05G5, inosinsaure, inosine phosphate, 1yfz, 5'-aInosinic acid, 1g9s, 1qk4, 1z6d, 5'-IMP, IMP, Inosine 5'-(dihydrogen phosphate), Inosine 5' monophosphate, [3h]inosine monophosphate, Inosinic acid (Standard), bmse000175, HYPOXANTHINE RIBOSIDE-5-PHOSPHORIC ACID, INOSINIC ACID [MI], SCHEMBL19255, ((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate, INOSINIC ACID, 5'-, SCHEMBL184240, SCHEMBL184241, GTPL5124, orb1302654, orb3025447, CHEMBL1207374, SCHEMBL29358651, BDBM19254, MSK6910, 1p17, 1p19, Inosine-5'-(dihydrogen phosphate), CYTOSINE INOSINATE [WHO-DD], I-5'-P, MFCD30342155, STL564942, AKOS015896456, AKOS015918470, AKOS030494380, DB04566, HY-108213R, NI10026, AS-56817, HY-108213, CS-0027540, NS00014854, C00130, F81515, 131I997, A1-01972, Q27074273, BB128E2C-BC89-4360-B0A0-190DDF5C0B57, I-5 inverted exclamation marka-P IMP Inosinic Acid, IMP, Inosine 5'-monophosphate - from Saccharomyces Cerevisiae, IMP (Inosine 5'-monophosphate, Inosinic acid, inosine monophosphate), [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen, ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate, [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate, Inosinic acid, 5′-inosinic acid, IMP, Inosine-5′-monophosphoric acid, Inosine 5′-monophosphate, 5′-inosinate, 2'-Inosine-5'-monophosphate, 5'-IMP, 5'-Inosinate, 5'-Inosine monophosphate, 5'-Inosinic acid, Hypoxanthosine 5'-monophosphate, Inosine 5'-monophosphate, Inosine 5'-phosphate, Inosine monophosphate, Ribosylhypoxanthine monophosphate, 2'-Inosine-5'-monophosphoric acid, 5'-Inosine monophosphoric acid, Hypoxanthosine 5'-monophosphoric acid, Inosine 5'-monophosphoric acid, Inosine 5'-phosphoric acid, Inosine monophosphoric acid, Ribosylhypoxanthine monophosphoric acid, Inosinate, IMP, Inosine-5'-monophosphate, Inosinic acids, Inosinate, sodium, monoPhosphate, inosine, monoPhosphate, ribosylhypoxanthine, Sodium inosinate, Acid, inosinic, Acids, inosinic, [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, inosine-5'-monophosphoric acid, 5′-Inosinic acid, 5′-IMP, IMP, Inosine 5′-monophosphate, Inosine 5′-phosphate, Inosinic acid, Inosine-5′-monophosphoric acid, Inosine 5′-(dihydrogen phosphate), [3,4-Dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, [3,4-Dihydroxy-5-(6-hydroxypurin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate, 485-83-6, 138240-72-9, 736074-82-1, 801187-33-7, 1080065-96-8, 1294552-14-9, 5'-IMP, 5'-Inosinate, 5'-Inosine monophosphate, 5'-Inosine monophosphoric acid, 5'-Inosinic acid, IMP, Inosinate, Inosine 5'-monophosphate, Inosine 5'-monophosphoric acid, Inosine 5'-phosphate, Inosine 5'-phosphoric acid, Inosine Monophosphate, Inosine monophosphoric acid, Inosine-5'-monophosphate, Inosine-5'-monophosphoric acid, Inosine-5'-phosphate, Inosine-5'-phosphoric acid, Inosinic acid, Ribosylhypoxanthine monophosphate, Ribosylhypoxanthine monophosphoric acid

Inosinic acid, also designated as E630, is an organic chemical compound from the nucleotide group, which is the salt of inosinic acid.
Inosinic acid is a white, odorless powder, obtained by synthetic reactions.
Inosinic acid is a purine ribonucleoside 5'-monophosphate having hypoxanthine as the nucleobase.


Inosinic acid has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite.
Inosinic acid is a purine ribonucleoside 5'-monophosphate.
Inosinic acid is a conjugate acid of an IMP(2-).


Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
Inosinic acid is formed by the deamination of AMP and when hydrolysed produces inosine.


Inosinic acid is the ribonucleotide of hypoxanthine and is the first compound formed during the synthesis of purine.
Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
Inosinic acid is a nucleotide present in muscle and other tissues.


Inosinic acid is formed by the deamination of AMP and when hydrolysed produces inosine.
Inosinic acid is the ribonucleotide of hypoxanthine and is the first compound formed during the synthesis of purine.
Inosinic acid is a naturally occurring ribonucleotide, chemically classified as a nucleoside monophosphate.


Inosinic acid consists of the nucleoside inosine (a ribose sugar linked to the base hypoxanthine) esterified at the 5′-position with a phosphate group.
Inosinic acid is an intermediate in purine nucleotide metabolism and plays a role in biochemical pathways such as the biosynthesis and degradation of purines.


Inosinic acid is also a key flavor-enhancing compound in food science, contributing to umami taste when used in combination with other nucleotides or glutamates.
Inosinic acid, also known as inosine monophosphate, IMP, 5'-inosinate or 5'-Inosinic acid, belongs to the class of organic compounds known as purine ribonucleoside monophosphates.


These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached.
Inosinic acid is also classified as a nucleotide (a nucleoside monophosphate).
Inosinic acid exists in all living species, ranging from bacteria to plants to humans.


Inosinic acid or IMP is important in metabolism.
Inosinic acid is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides.
Inosinic acid can also be formed by the deamination of adenosine monophosphate by AMP deaminase.


GMP is formed by the inosinate oxidation to xanthylate (XMP).
Within humans, inosinic acid participates in a number of enzymatic reactions.
In particular, inosinic acid can be converted into phosphoribosyl formamidocarboxamide; which is catalyzed by the bifunctional purine biosynthesis protein.


In addition, inosinic acid can be converted into xanthylic acid; which is catalyzed by the enzyme inosine-5'-monophosphate dehydrogenase 1.
Inosinic acid belongs to the class of organic compounds known as purine ribonucleoside monophosphates.
These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached.


Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
Inosinic acid is a nucleotide present in muscle and other tissues.
Inosinic acid is formed by the deamination of AMP and when hydrolysed produces inosine.


Inosinic acid is the ribonucleotide of hypoxanthine and is the first compound formed during the synthesis of purine.
Inosinic acid is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).
Inosinic acid, also known as inosine monophosphate (IMP), is a nucleotide that plays a crucial role in cellular metabolism and energy transfer.


Inosinic acid is a key intermediate in the synthesis of purine nucleotides and is involved in various biochemical pathways, including the synthesis of RNA and DNA.
Inosinic acid is characterized by its molecular formula, which includes a ribose sugar, a phosphate group, and a purine base (hypoxanthine).


Inosinic acid is soluble in water and exhibits a slightly acidic nature due to the presence of the phosphate group.
Inosinic acid is often found in muscle tissue and is associated with the umami flavor in food, making it an important compound in the food industry, particularly in flavor enhancers.


Additionally, Inosinic acid has potential applications in biochemistry and medicine, as it can influence cellular signaling and energy metabolism.
Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.


Inosinic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Inosinic acid has been reported in Drosophila melanogaster, Arabidopsis thaliana, and other organisms with data available.
Inosinic Acid is a purine ribonucleotide with hypoxanthine as the base and one phosphate group attached to the sugar moiety.


Inosinic acid and its salt forms are used as flavor enhancers in industrial food production.
In vivo, Inosinic acid is involved in purine metabolism and acts as an intermediate in the synthesis of adenine and guanine, which are precursors for the second messenger signaling molecules adenosine monophosphate (AMP) and guanosine monophosphate (GMP), respectively.


Inosinic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
Inosinic acid or inosine monophosphate (IMP) is a nucleotide (that is, a nucleoside monophosphate).
Inosinic acid is widely used as a flavor enhancer, it is typically obtained from chicken byproducts or other meat industry waste.


Inosinic acid is important in metabolism.
Inosinic acid is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides.
Inosinic acid can also be formed by the deamination of adenosine monophosphate by AMP deaminase.


Inosinic acid can be hydrolysed to inosine.
The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in Saccharomyces cerevisiae and containing (d)ITPase and (d)XTPase activities, hydrolyzes inosine triphosphate (ITP) releasing pyrophosphate and IMP.


Important derivatives of Inosinic acid include the purine nucleotides found in nucleic acids and adenosine triphosphate, which is used to store chemical energy in muscle and other tissues.
Inosinic acid is a purine ribonucleoside 5'-monophosphate having hypoxanthine as the nucleobase.


Inosinic acid is a purine ribonucleoside 5'-monophosphate and an inosine phosphate.
Inosinic acid is a conjugate acid of an IMP(2-).
Inosinic acid, also known as 5'-inosinate or 5'-IMP, belongs to the class of organic compounds known as purine ribonucleoside monophosphates.


These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached.
Inosinic acid is an extremely weak basic (essentially neutral) compound (based on its pKa).
Inosinic acid exists in all living species, ranging from bacteria to humans.


Within humans, inosinic acid participates in a number of enzymatic reactions.
In particular, inosinic acid can be converted into phosphoribosyl formamidocarboxamide through the action of the enzyme bifunctional purine biosynthesis protein purh.


In addition, inosinic acid can be converted into xanthylic acid through its interaction with the enzyme inosine-5'-monophosphate dehydrogenase 1.
Inosinic acid is an odorless-tasting compound.


Outside of the human body, Inosinic acid has been detected, but not quantified in, several different foods, such as hickory nuts, turnips, pepper (spice), mountain yams, and muskmelons.
This could make inosinic acid a potential biomarker for the consumption of these foods.


A purine ribonucleoside 5'-monophosphate having hypoxanthine as the nucleobase.
Inosinic acid, also known as inosine monophosphate (IMP), is a nucleotide found naturally in animal tissues and certain plants.
Historically, inosinic acid and its derivatives have played a notable role in traditional and modern medicinal practices.


In ancient times, extracts from meat and fish—rich in inosinic acid—were commonly used as restorative broths to aid convalescence, improve stamina, and enhance overall vitality.
These nutrient-dense preparations were valued for their ability to promote recovery from illness and fatigue, particularly in Eastern and Western herbal traditions.


With the advancement of nutritional science, inosinic acid gained recognition for its contribution to cellular energy metabolism, acting as a precursor to adenosine monophosphate (AMP) and adenosine triphosphate (ATP), molecules essential for energy transfer in the body.
This attribute led to Inosinic acid's inclusion in remedies aimed at boosting physical endurance, supporting immune function, and accelerating healing.


In Japan, inosine-containing supplements have been utilized to support cardiovascular health and enhance physical performance, reflecting a deep-rooted appreciation for Inosinic acid's restorative properties.
Herbal combinations featuring inosinic acid are particularly prevalent in Asian cuisine and medicine, where it is paired with botanicals such as ginseng, goji berries, and medicinal mushrooms.


These synergistic blends are designed to harness the energy-providing benefits of inosinic acid alongside the adaptogenic and immune-boosting properties of herbs.
Not only does inosinic acid improve the palatability of these formulations through its umami taste, but it also amplifies their nutritional value, making it a cherished component in both culinary and healing traditions.


Overall, inosinic acid’s historical and ongoing contributions to wellness highlight its importance as a natural and effective health-promoting ingredient.
Inosinic acid (Standard) is the analytical standard of Inosinic acid.


Inosinic acid is intended for research and analytical applications.
Inosinic acid is an endogenous metabolite.

USES and APPLICATIONS of INOSINIC ACID:
Inosinic acid (E630) is widely used in the food industry as an additive that improves the flavor and aroma of food products.
Inosinic acid is often used as a flavor enhancer, especially in meat products, soups, broths, snacks and instant condiments.
Its ability to improve flavor makes Inosinic acid a popular ingredient in many prepared foods.


Inosinic acid is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).
Inosinic acid is widely used as a flavor enhancer.
In the food industry, Inosinic acid is known as E number reference E630.


Inosinic acid can be converted into various salts including disodium inosinate (E631), dipotassium inosinate (E632), and calcium inosinate (E633).
These three inosinate compounds are used as flavor enhancers for the basic taste umami.


These inosinate salts are mostly used in soups, sauces, and seasonings for the intensification and balance of the flavor of meat.
Inosinic acid is typically obtained from chicken byproducts or other meat industry waste.
Inosinic acid is used for identification in chemical databases and regulatory frameworks.


Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs.
Inosinic acid is used for laboratory and analytical use only.


-Inosinic acid can be converted into various salts including disodium inosinate (E631), dipotassium inosinate (E632), and calcium inosinate (E633).
These three compounds are used as flavor enhancers for the basic taste umami or savoriness with a comparatively high effectiveness.
They are mostly used in soups, sauces, and seasonings for the intensification and balance of the flavor of meat.


-Applications of Inosinic acid: 
Analytical method development and validation,
Routine quality control (HPLC, LC-MS, GC, etc.),
Research and formulation studies,
Stability testing and impurity profiling.


-In the food industry, Inosinic acid and its salts such as disodium inosinate are used as flavor enhancers.
Inosinic acid is known as E number reference E630.
The inosinate synthesis is complex, beginning with a 5-phosphoribosyl-1-pyrophosphate (PRPP).
Enzymes taking part in IMP synthesis constitute a multienzyme complex in the cell.

Evidence demonstrates that there are multifunctional enzymes, and some of them catalyze non-sequential steps in the pathway.
Within a few steps inosinate becomes AMP or GMP.

Both compounds are RNA nucleotides.
AMP differs from inosinate by the replacement of Inosinic acid's carbon-6 carbonyl with an amino group.

The interconversion of AMP and Inosinic acid occurs as part of the purine nucleotide cycle.
GMP is formed by the inosinate oxidation to xanthylate (XMP), and afterwards adds an amino group on carbon 2.

Hydrogen acceptor on inosinate oxidation is NAD+.
Finally, carbon 2 gains the amino group by spending an ATP molecule (which becomes AMP+2Pi).
While AMP synthesis requires GTP, GMP synthesis uses ATP.

That difference offers an important regulation possibility.
Inosinate and many other molecules inhibit the synthesis of 5-phosphoribosylamine from 5-phosphoribosyl-1-pyrophosphate (PRPP), disabling the enzyme that catalyzes the reaction: glutamine-5-phosphoribosyl-1-pyrophosphate-amidotransferase.

In other words, when levels of inosinate are high, glutamine-5-phosphoribosyl-1-pyrophosphate-amidotransferase is inhibited, and, as a consequence, inosinate levels decrease.
Also, as a result, adenylate and guanylate are not produced, which means that RNA synthesis cannot be completed because of the lack of these two important RNA nucleotides.

PROPERTIES of INOSINIC ACID:
Inosinic acid is soluble in water and has a distinctive taste, which is often used in the food industry as a flavor enhancer.
Inosinic acid is stable over a wide pH range, making it suitable for use in a variety of foods.

WHERE TO BUY INOSINIC ACID?
Inosinic acid (E630) is available in convenience stores and online stores specializing in food chemicals.
Inosinic acid can also be found in wholesalers for the food industry.

INOSINIC ACID AND ITS FUNCTIONS IN FOOD
Inosinic acid (E630) acts as a flavor enhancer in food, making foods more intense and fuller in flavor.
Inosinic acid is particularly useful in products where natural flavors are weak or need to be enhanced.
However, like any additive, Inosinic acid should be used in moderation and in accordance with safety guidelines and recommended dosage.

KEY FEATURES of INOSINIC ACID:
*High-Purity Reference Standard : 
Manufactured under controlled conditions to deliver consistent and reliable purity.

*Pharmacopeia Traceable : 
Reference material aligned with major international pharmacopeial specifications.

*Regulatory-Compliant Quality : 
Produced under robust quality management systems meeting global compliance norms.

*Reliable Analytical Performance : 
Trusted standard for method validation, calibration, and QC testing.

*Batch-Specific CoA Available : 
Detailed Certificate of Analysis provided upon request.

ALTERNATIVE PARENTS of INOSINIC ACID:
*Pentose phosphates 
*Glycosylamines 
*6-oxopurines 
*Hypoxanthines 
*Monosaccharide phosphates 
*Pyrimidones 
*Monoalkyl phosphates 
*N-substituted imidazoles 
*Heteroaromatic compounds 
*Tetrahydrofurans 
*Vinylogous amides 
*1,2-diols 
*Lactams 
*Secondary alcohols 
*Oxacyclic compounds 
*Azacyclic compounds 
*Organic oxides 
*Organopnictogen compounds 
*Hydrocarbon derivatives 
*Organonitrogen compounds 

SUBSTITUENTS of INOSINIC ACID:
*Purine ribonucleoside monophosphate
*Pentose phosphate
*Pentose-5-phosphate
*Glycosyl compound
*N-glycosyl compound
*6-oxopurine
*Hypoxanthine
*Monosaccharide phosphate
*Pentose monosaccharide
*Imidazopyrimidine
*Purine
*Pyrimidone
*Monoalkyl phosphate
*Alkyl phosphate
*Pyrimidine
*Phosphoric acid ester
*Organic phosphoric acid derivative
*N-substituted imidazole
*Monosaccharide
*Tetrahydrofuran
*Vinylogous amide
*Azole
*Imidazole
*Heteroaromatic compound
*Secondary alcohol
*1,2-diol
*Lactam
*Organoheterocyclic compound
*Azacycle
*Oxacycle
*Alcohol
*Organic oxide
*Organopnictogen compound
*Organic oxygen compound
*Organic nitrogen compound
*Organooxygen compound
*Organonitrogen compound
*Hydrocarbon derivative
*Aromatic heteropolycyclic compound

TRADITIONAL AND SCIENTIFIC VALIDATION of INOSINIC ACID:
Inosinic acid, also known as inosine monophosphate (IMP), is a naturally occurring nucleotide found in various animal and plant tissues.
Historically, Inosinic acid has been recognized as a key flavor enhancer, particularly in meats and broths, due to its umami properties.
Inosinic acid's use in nutritional products is rooted in its role as a precursor for nucleotides and nucleosides, which are essential for numerous cellular processes, including energy transfer and the synthesis of RNA and DNA.

Scientific validation for inosinic acid’s inclusion in nutritional supplements primarily comes from its metabolic significance.
Inosinic acid participates in the purine nucleotide cycle and has been studied for its potential to support cellular energy metabolism.
Some studies have investigated inosine supplementation (a related compound) for Inosinic acid's neuroprotective effects and potential benefits in conditions such as multiple sclerosis and stroke, though results are mixed and often focus on inosine rather than IMP itself.

While direct clinical evidence regarding the specific benefits of inosinic acid in humans remains limited, its established role in basic biochemistry, along with positive findings in preclinical studies, supports its continued use as a functional ingredient in nutrition.
More research is needed to fully elucidate its health effects, but current data suggest Inosinic acid may contribute to overall cellular health and metabolic balance.

PHYSICAL and CHEMICAL PROPERTIES of INOSINIC ACID:
CAS Number: 131-99-7
EC Number: Not available
IUPAC Name: {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid
Traditional Name: inosine-5'-monophosphate
Chemical Formula: C10H13N4O8P
Molecular Weight: 348.21 g/mol
Exact Mass: 348.04710038 Da
Monoisotopic Mass: 348.04710038 Da
XLogP3: -3
Hydrogen Bond Donor Count: 5

Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 4
Topological Polar Surface Area: 176 Ų
Heavy Atom Count: 23
Formal Charge: 0
Complexity: 555
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 4
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
SMILES: O[C@@H]1C@@HOC@HN1C=NC2=C1N=CNC2=O
InChI: InChI=1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI Key: GRSZFWQUAKGDAV-KQYNXXCUSA-N
Appearance: White crystalline powder (estimated)
Assay: 97.00 to 100.00%

Boiling Point: 851.37 °C at 760 mm Hg (estimated)
Flash Point: 876 °F TCC (468.7 °C) (estimated)
LogP (o/w): -3.707 (estimated)
Solubility: Water 5921 mg/L @ 25 °C (estimated), slightly soluble in alcohol
Physical State: Solid
Color: No data available
Odor: No data available
Melting Point: No data available
Boiling Point Range: No data available
Flash Point: Not applicable

Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: No data available
Viscosity: No data available
Water Solubility: No data available
Partition Coefficient: No data available
Vapor Pressure: No data available
Density: No data available
Explosive Properties: Not classified as explosive
Oxidizing Properties: None
Other Safety Information: No data available

Chemical formula: C10H13N4O8P
Molar mass: 348.208 g·mol−1
Molecular Weight: 348.21 g/mol
XLogP3: -3
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 4
Exact Mass: 348.04710038 Da
Monoisotopic Mass: 348.04710038 Da
Topological Polar Surface Area: 176 Ų
Heavy Atom Count: 23

Formal Charge: 0
Complexity: 555
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 4
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Preferred Name: Inosinic acid

Other Names (Synonyms): Inosinic acid, 5′-inosinic acid, IMP, Inosine-5′-monophosphoric acid, Inosine 5′-monophosphate, 5′-inosinate
Molecular Formula: C10H13N4O8P
Molecular Weight: 348.21 g/mol
CAS Number: 131-99-7
PubChem CID: 135398640
IUPAC Name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate
Structure: A purine base (hypoxanthine) attached to a ribose sugar with a phosphate group at the 5′-carbon
Water Solubility: Soluble in water; forms aqueous solutions
Solubility in Organic Solvents: Generally poorly soluble in ethanol; its salts (e.g., disodium IMP) show similar behavior

Stability: Stable under normal storage and handling; may decompose at very high temperatures
Physical State: Solid at room temperature
Density: 2.3 g/cm³
Boiling Point: Very high, not typically relevant owing to decomposition before boiling
LogP: Negative (indicative of water solubility)
Chemical Formula: C10H13N4O8P
Average Molecular Weight: 348.206
Monoisotopic Molecular Weight: 348.047099924
IUPAC Name: {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid
Traditional Name: inosine-5'-monophosphate

CAS Registry Number: 131-99-7
SMILES: O[C@@H]1C@@H
OC@H
N1C=NC2=C1N=CNC2=O
InChI Identifier: InChI=1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI Key: GRSZFWQUAKGDAV-KQYNXXCUSA-N
Beilstein Number: 0630517
MDL: MFCD00066754
XlogP3: -3.70 (est)
Molecular Weight: 348.20897200
Formula: C10 H13 N4 O8 P

Appearance: white crystalline powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 851.37 °C. @ 760.00 mm Hg (est)
Flash Point: 876.00 °F. TCC (468.70 °C.) (est)
logP (o/w): -3.707 (est)
Soluble in:
water, 5921 mg/L @ 25 °C (est)
alcohol, slightly

Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapour density: No data available
Particle characteristics: No data available

Explosive properties: Not classified as explosive
Oxidizing properties: none
Molecular Weight: 348.21
Exact Mass: 348.21
EC Number: 205-045-1
UNII: TAO7US05G5
DSSTox ID: DTXSID4044294
HScode: 29389090
Chemical Formula: C10H13N4O8P

Weight: Average: 348.206
Monoisotopic: 348.047099924
InChI Key: GRSZFWQUAKGDAV-KQYNXXCUSA-N
InChI: InChI=1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
CAS number: 131-99-7
IUPAC Name: {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic acid
Traditional IUPAC Name: inosine-5'-monophosphate
SMILES: O[C@@H]1C@@HOC@H
N1C=NC2=C1N=CNC2=O

Water Solubility: 3.05 g/L
logP: -2
logP: -2.9
logS: -2.1
pKa (Strongest Acidic): 1.31
pKa (Strongest Basic): 0.49
Physiological Charge: -2
Hydrogen Acceptor Count: 9
Hydrogen Donor Count: 5
Polar Surface Area: 175.73 Ų

Rotatable Bond Count: 4
Refractivity: 72.2 m³•mol⁻¹
Polarizability: 29.14 ų
Number of Rings: 3
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes

FIRST AID MEASURES of INOSINIC ACID:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of INOSINIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

 

FIRE FIGHTING MEASURES of INOSINIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of INOSINIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of INOSINIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of INOSINIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available

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