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ISOBUTYL AMINE

ISOBUTYL AMINE


Isobutyl amine appears as a clear colorless liquid with a fishlike odor. 
Flash point: 15 °F. 
Isobutyl amine is less dense (6.1 lb / gal) than water. 
Isobutyl amine's vapors heavier than air. 


CAS: 78-81-9
European Community (EC) Number: 201-145-4

IUPAC Name: 2-methylpropan-1-amine

Molecular Formula: C4H11N
Molecular Weight: 73.14 g/mol

ISOBUTYLAMINE, 78-81-9, 2-methylpropan-1-amine, 1-Amino-2-methylpropane, 2-Methylpropylamine, Monoisobutylamine, Valamine, iso-Butylamine, 1-Propanamine, 2-methyl-, 2-Methylpropanamine, I-Butylamine, 2-Methyl-1-propanamine, 3-Methyl-2-propylamine, 2-Methyl-1-Aminopropane, isobutyl amine, NSC 8028, iso-C4H9NH2, 2-methyl-1-propylamine, MFCD00008146, 1H60H4LOHZ, NSC-8028, Isobutylamine, 99%, CCRIS 6250, HSDB 612, EINECS 201-145-4, UN1214, UNII-1H60H4LOHZ, isobutyl-amine, iso-butyl amine, AI3-24039, Valamine, N-iso-butylamine, iBuNH2, Isobutylamine, 8CI, 2-methylpropyl amine, (2-methylpropyl)amine, i-BuNH2, 2-methylpropane-1-amine, 1-amino-2-methyl-propane, ISOBUTYLAMINE [MI], ISOBUTYLAMINE [FHFI], ISOBUTYLAMINE [HSDB], 2-Methyl-1-propanamine, 9CI, DTXSID9025459, FEMA NO. 4239, CHEBI:15997, WLN: Z1Y1&1, NSC8028, Isobutylamine, analytical standard, STR01259, AMINO-2-METHYL PROPANE, 1-, AKOS000119607, UN 1214, Isobutylamine, purum, >=98.0% (GC), I0095, NS00021357, EN300-20218, Isobutylamine [UN1214] [Flammable liqid], C02787, Q416655, J-510080, F2190-0360, InChI=1/C4H11N/c1-4(2)3-5/h4H,3,5H2,1-2H


Isobutyl amine is used as pharmaceutical intermediate.

Isobutyl amine is an alkylamine having isobutyl as the alkyl group. 
Isobutyl amine has been isolated from Sambucus nigra (Elderberry). 
Isobutyl amine has a role as a plant metabolite. 
Isobutyl amine is a conjugate base of a 2-methylpropanaminium.

Isobutyl amine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).

Isobutyl amine is an organic chemical compound (specifically, an amine) with the formula (CH3)2CHCH2NH2, and occurs as a colorless liquid.
Isobutyl amine is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and tert-butylamine. 
Isobutyl amine is the decarboxylated form of the amino acid valine, and the product of the metabolism thereof by the enzyme valine decarboxylase.

Isobutyl amine is a flammable liquid, miscible with water, alcohol, and ether.
Butyl amines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:


Experimental Properties: 

Color / Form: Colorless liquid
Odor: Amine odor
Boiling Point: 154 to 156 °F at 760 mmHg
Melting Point: -121 °F
Flash Point: 15 °F 
Solubility: Very soluble
1000 mg/mL at 25 °C
Density: 0.739 at 68 °F
Vapor Density: 2.5 
Vapor Pressure: 100 mmHg at 65.8 °F
LogP: log Kow = 0.73
Autoignition Temperature: 712 °F
Corrosivity: Strongly caustic
Heat of Combustion: -3013.5 kJ/mol at 25 °C (liquid); -3047.4 kJ/mol at 25 °C (gas)
Heat of Vaporization: 33.85 kJ/mol at 25 °C
Surface Tension: 21.75 mN/m at 25 °C; 19.02 mN/m at 50 °C
Index of refraction: 1.3988 at 17 °C/D
Dissociation Constants: pKa = 10.68 at 25 °C (conjugate acid)


Isobutyl amine is used as pharmaceutical intermediate.

Isobutyl amine may be used in the synthesis of N-i-butyl-9(Z),12(Z),15(Z)-octadecatrienamide by reacting with trilinolenin. 
Isobutyl amine can also react with tropolone to form a hydrogen-bonded complex, iso-butyl-ammonium 7-oxo-cyclo-hepta-1,3,5-trien-1-olate. 
Fullerene (C60) can undergo oxyamination with isobutylamine to form polyamines.


Isobutyl amine is a chemical compound that is used as a solvent and a reagent in organic synthesis. 
Isobutyl amine undergoes a reaction with trifluoroacetic acid to generate an amide or nitro group. 
The reaction mechanism of this process involves the formation of an intermediate carbocation, which reacts with the nucleophile trifluoroacetic acid to form the product. The product then undergoes hydrolysis to regenerate the initial starting material. 
This process can be followed by titration calorimetry, kinetic data, and analytical methods such as gas chromatography-mass spectrometry (GC-MS). 
Isobutylamine has been shown to have promising applications in autoimmune diseases by activating cb2 receptors, which are involved in inflammatory responses and pain perception.


Isobutyl amine is a member of the chemical class known as Alkylamines. 
These are organic compounds containing an alkylamine group.


Isobutyl amine occurs as a colorless to yellow, clear liquid having a characteristic odor.

Isobutyl amine is used as pharmaceutical intermediate.

Isobutyl amine is an alkylamine having isobutyl as the alkyl group. 
Isobutyl amine has been isolated from Sambucus nigra (Elderberry). 
Isobutyl amine has a role as a plant metabolite. 
Isobutyl amine is a conjugate base of a 2-methylpropanaminium.


Identification:
Determine the infrared absorption spectrum of Isobutylamine as directed in the Liquid Film Method under Infrared Spectrophotometry, and compare it with the Reference Spectrum. 
Both spectra exhibit similar intensities of absorption at the same wavenumbers.


Isobutyl amine produces toxic oxides of nitrogen during combustion.


 

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