L-Tryptophane is an essential amino acid that plays a crucial role in protein synthesis and serves as a precursor for serotonin, a neurotransmitter that regulates mood, sleep, and appetite.
L-Tryptophane is found naturally in many protein-rich foods, such as eggs, fish, white meat, dairy products, and dark chocolate.
L-Tryptophane is used as a precursor to niacin, indole alkaloids and serotonin.
CAS Number: 73-22-3
EC Number: 200-795-6
Molecular Formula: C11H12N2O2
Molecular Weight: 204.23 g/mol
Synonyms: L-tryptophan, tryptophan, 73-22-3, L-Tryptophane, Tryptophane, (S)-Tryptophan, trofan, tryptacin, (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid, Ardeytropin, Pacitron, Indole-3-alanine, L-Tryptofan, L-Trp, L-(-)-Tryptophan, L-beta-3-Indolylalanine, 3-Indol-3-ylalanine, triptofano, (-)-Tryptophan, 1-beta-3-Indolylalanine, Tryptophan, L-, 1H-Indole-3-alanine, Tryptophanum, 1beta-3-Indolylalanine, 2-Amino-3-indolylpropanoic acid, Tryptophanum [Latin], (L)-TRYPTOPHAN, (S)-alpha-Amino-1H-indole-3-propanoic acid, alpha'-Amino-3-indolepropionic acid, L-alpha-Aminoindole-3-propionic acid, (S)-alpha-Aminoindole-3-propionic acid, L-alpha-amino-3-indolepropionic acid, EH 121, Alanine, 3-indol-3-yl-, Trytophan-, L-Alanine, 3-(1H-indol-3-yl)-, 1H-Indole-3-alanine, (S)-, NCI-C01729, AI3-18478, Indole-3-propionic acid, alpha-amino-, Propionic acid, 2-amino-3-indol-3-yl-, (S)-alpha-amino-beta-(3-indolyl)-propionic acid, 1H-Indole-3-propanoic acid, alpha-amino-, (S)-, Tryptophan ((-),l,s), 8DUH1N11BX, NSC 13119, DTXSID5021419, CHEBI:16828, (S)-alpha-Amino-beta-indolepropionic acid, NSC-13119, DTXCID801419, alpha-Aminoindole-3-propionic acid, Tryptophanum (Latin), alpha-Amino-beta-(3-indolyl)-propionic acid, (2S)-2-amino-3-(1H-indol-3-yl)propanoate, CHEBI:27897, Levotryptophan, Naturruhe, l-tryptophanum, (2S)-2-azaniumyl-3-(1H-indol-3-yl)propanoate, l tryptophan, Optimax wv, ratio Tryptophan, ratio-Tryptophan, Gppe pdr sach, PMS Tryptophan, L-Tryptophan High, L-Tryptophan 7423, L Tryptophan ratiopharm, RefChem:6508, L-Tryptophan High 7424, N06AX02, (2S)-2-Amino-3-(indol-3-yl)propanoic acid, (S)-2-Amino-3-(1H-indol-3-yl)-propanoic acid, 200-795-6, L-TTP, h-Trp-oh, Kalma, Tryptan, L(-)-Tryptophan, Tryptophan (VAN), Tryptophan (H-3), Triptofano [Spanish], Lyphan, Tryptophane [French], Tryptophan [USAN:INN], Sedanoct, trp, 1H-Indole-3-alanine (VAN), CCRIS 617, MFCD00064340, alpha-Amino-3-indolepropionic acid, L-, HSDB 4142, (S)-2-Amino-3-(3-indolyl)propionic acid, (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid, Lopac-T-0254, CHEMBL54976, M02943, l-b-3-Indolylalanine, 3-beta-Indolylalanine, CAS-73-22-3, Propionic acid, 2-amino-3-indol-3-yl, L-Tryptophan (9CI), Tryptophan (USP/INN), (S)-a-Amino-b-indolepropionic acid, (S)-a-Aminoindole-3-propionic acid, Alanine, 3-indol-3-yl, EINECS 200-795-6, L-Tryptophan-13C11,15N2, UNII-8DUH1N11BX, trytophan, (S)-a-Amino-1H-indole-3-propanoic acid, TRP-01, L-Trytophan, Tryptophan CRS, 1qaw, 80206-30-0, 202406-50-6, L-Trp-OH, Tryptophan [WHO-DD], 2a4m, TRYPTOPHAN [II], TRYPTOPHAN [MI], L-Tryptophan (JP18), L-Tryptophan (standard), TRYPTOPHAN [INN], S(-)-1-alpha-Aminoindole-3-propionic acid, TRYPTOPHAN [HSDB], TRYPTOPHAN [USAN], Tryptophan (L-Tryptophan), TRYPTOPHAN [VANDF], Tryptophan, L- (8CI), bmse000050, bmse000868, bmse001017, Epitope ID:136043, EC 200-795-6, T 0254, L-TRYPTOPHAN [FCC], L-TRYPTOPHAN [JAN], SCHEMBL7328, TRYPTOPHAN [MART.], 2-Amino-3-indolylpropanoate, (S)-(-)-2-Amino-3-(3-indolyl)propionic Acid, (S)-1H-Indole-3-alanine, Lopac0_001183, GTPL717, L-TRYPTOPHAN [VANDF], MLS001056750, DivK1c_000457, Tryptophan EP Impurity C-D4, L-TRYPTOPHAN [USP-RS], (s)-a-amino-b-indolepropionate, orb1297181, orb1310615, orb3139585, orb3139805, SCHEMBL1119669, 151A3008-4CFE-40C9-AC0B-467EF0CB50EA, SCHEMBL23141133, SCHEMBL28341856, (S)-a-Aminoindole-3-propionate, BDBM21974, HMS501G19, HY-N0623R, KBio1_000457, MSK1418, TRYPTOPHAN [EP MONOGRAPH], 3-(1H-indol-3-yl)-L-Alanine, L-a-Amino-3-indolepropionic acid, NINDS_000457, HMS3263N07, Pharmakon1600-01500600, TRYPTOPHAN [USP MONOGRAPH], HY-N0623, STR02722, (S)-alpha-Aminoindole-3-propionate, Tox21_201246, Tox21_300359, Tox21_501183, EBC-01051, NSC757373, s3987, (s)-alpha-amino-beta-indolepropionate, L-Tryptophan, Vetec(TM), 98.5%, (S)-a-Amino-1H-indole-3-propanoate, AKOS015854052, Indoe-3-propionic acid, alpha-amino-, CCG-205257, CS-W020011, DB00150, ET06029, LP01183, NSC-757373, SDCCGSBI-0051150.P002, IDI1_000457, L-2-Amino-3-(3-indolyl)propionic acid, NCGC00015994-01, NCGC00094437-01, NCGC00094437-02, NCGC00094437-03, NCGC00094437-04, NCGC00094437-08, NCGC00254424-01, NCGC00258798-01, NCGC00261868-01, (S)-alpha-Amino-1H-indole-3-propanoate, AC-17050, BP-13286, IS_TRYPTOPHAN-2,4,5,6,7-D5, SMR000326686, TS-04426, propanoic acid, 2-amino-3-(3-indolyl)-, DB-029986, L-Tryptophan, BioUltra, >=99.5% (NT), EU-0101183, NS00003513, (S)-Tryptophan 1H-Indole-3-alanine, (S)-, EN300-52634, C00078, D00020, L-.ALPHA.-AMINO-3-INDOLEPROPIONIC ACID, L-Tryptophan, reagent grade, >=98% (HPLC), P16427, T-8320, AB00373874_05, L-Tryptophan, Vetec(TM) reagent grade, >=98%, (S)-2-amino-3-(1H-Indol-3-yl)-propionic acid, L-Tryptophan, Cell Culture Reagent (H-L-Trp-OH), Q181003, SR-01000075590, N-ACETYLTRYPTOPHAN IMPURITY A [EP IMPURITY], SR-01000075590-1, BRD-K83776863-001-05-5, BRD-K83776863-001-08-9, F0001-2364, Z756440056, 1H-INDOLE-3-PROPANOIC ACID, .ALPHA.-AMINO-, (S)-, L-Tryptophan, certified reference material, TraceCERT(R), Tryptophan, European Pharmacopoeia (EP) Reference Standard, L-Tryptophan, United States Pharmacopeia (USP) Reference Standard, Tadalafil Impurity O; Tryptophan; N-Acetyltryptophan EP Impurity A, L-Tryptophan, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
L-Tryptophane is an essential aromatic amino acid that the human body cannot synthesize and must obtain from dietary sources.
L-Tryptophane serves as a precursor for important biomolecules such as serotonin, melatonin, and niacin (vitamin B3), playing a key role in mood regulation, sleep cycles, and overall neurological function.
L-Tryptophane is widely used in nutraceutical, pharmaceutical, and food applications due to its physiological importance.
L-Tryptophane is an essential amino acid that plays a crucial role in protein synthesis and serves as a precursor for serotonin, a neurotransmitter that regulates mood, sleep, and appetite.
L-Tryptophane is widely recognized for its applications in the pharmaceutical and nutraceutical industries, particularly in the formulation of dietary supplements aimed at improving mental health and sleep quality.
Researchers and industry professionals utilize L-Tryptophane for its potential benefits in managing conditions such as depression, anxiety, and insomnia, making it a valuable ingredient in wellness products.
In addition to its mental health applications, L-Tryptophane is also employed in animal nutrition to enhance growth and feed efficiency in livestock.
L-Tryptophane's unique ability to promote serotonin production not only supports animal welfare but also improves overall productivity in agricultural settings.
With its versatile applications and significant health benefits, L-Tryptophane stands out as a key compound for both human health and animal nutrition, making it an essential addition to any formulation focused on enhancing well-being.
L-Tryptophane is used along with other medications to treat mental depression.
Also, L-Tryptophane is used along with lithium to treat bipolar disorder.
L-Tryptophane is an essential amino acid for the human body, but it cannot be synthesized.
L-Tryptophane must be obtained through diet or supplementation, particularly with dietary supplements.
L-Tryptophane is found naturally in many protein-rich foods, such as eggs, fish, white meat, dairy products, and dark chocolate.
In the brain, L-Tryptophane is converted into 5-HTP and then into serotonin, a neurotransmitter involved in regulating mood and sleep, and promoting emotional well-being thanks to its calming effect.
Once converted into serotonin, L-Tryptophane is itself a precursor to melatonin, the hormone that regulates the sleep-wake cycle.
L-Tryptophane is an essential amino acid which is necessary for normal growth in infants and for nitrogen balance in adults.
L-Tryptophane acts as a natural dietary supplement and used as an antidepressant, anxiolytic and sleep aid.
L-Tryptophane is used as a precursor to niacin, indole alkaloids and serotonin.
L-Tryptophane acts as an important intrinsic fluorescent probe, which finds to estimate the nature of microenvironment of the Tryptophane.
Uses of L-Tryptophane:
L-Tryptophane is used in biochemical research.
L-Tryptophane is used as a nutritional supplement for foods.
L-Tryptophane is used as a dietary supplement, for research, cereal enrichment, and as a medication.
L-Tryptophane is permitted for use as an inert ingredient in non-food pesticide products.
L-Tryptophane is an essential amino acid which is necessary for normal growth in infants and for nitrogen balance in adults.
L-Tryptophane acts as a natural dietary supplement and used as an antidepressant, anxiolytic and sleep aid.
L-Tryptophane is used as a precursor to niacin, indole alkaloids and serotonin.
L-Tryptophane acts as an important intrinsic fluorescent probe, which finds to estimate the nature of microenvironment of the tryptophan.
Solubility of L-Tryptophane:
L-Tryptophane is soluble in water, ammonia, hot alcohol, alkali hydroxides and dilute acids.
L-Tryptophane is slightly soluble in acetic acid and ethanol.
L-Tryptophane is insoluble in chloroform and ethyl ether.
Stability and Reactivity of L-Tryptophane:
Chemical stability:
Stable under recommended conditions.
Reactivity:
No hazardous reactions expected.
Conditions to avoid:
Light exposure.
Excessive heat.
Moisture.
Incompatible materials:
Strong oxidizing agents.
Hazardous decomposition products:
Nitrogen oxides (NOₓ) may form.
Carbon oxides (CO, CO₂) may be released.
Handling and Storage of L-Tryptophane:
Handling:
Avoid dust formation.
Avoid inhalation of dust.
Storage:
Store in a cool, dry place.
Storage conditions:
Keep container tightly closed.
Protect from light.
Packaging materials:
Use sealed, light-resistant containers.
Shelf life:
Approximately 24 months.
First Aid Measures of L-Tryptophane:
Inhalation:
Move to fresh air.
Skin contact:
Wash with water.
Eye contact:
Rinse with water.
Ingestion:
Seek medical advice if necessary.
Firefighting Measures of L-Tryptophane:
Suitable extinguishing media:
Water spray.
Foam.
Carbon dioxide (CO₂).
Dry chemical.
Hazards:
May produce toxic fumes when burned.
Protective equipment:
Use standard protective gear.
Accidental Release Measures of L-Tryptophane:
Personal precautions:
Avoid dust inhalation.
Spill response:
Sweep and collect material.
Environmental precautions:
Avoid release into the environment.
Cleanup methods:
Dispose according to regulations.
Exposure Controls / Personal Protection of L-Tryptophane:
Respiratory protection:
Use dust mask if needed.
Eye protection:
Use safety goggles.
Skin protection:
Wear protective gloves.
Hygiene measures:
Wash after handling.
Engineering controls:
Ensure adequate ventilation.
Identifiers of L-Tryptophane:
CAS Number: 73-22-3
Purity: 98.5 - 101.5% (Assay by titration)
Grade: Meets USP Specification
Molecular Formula: C11H12N2O2
Molecular Weight: 204.2
MDL Number: MFCD00064340
PubChem ID: 1148
Appearance: White to slightly yellowish crystals or crystalline powder
Optical Rotation: [a]20D = -29.4 to -32.8 º(C=10 mg/mL in water)
Molecular formula: C₁₁H₁₂N₂O₂
Molecular weight: 204.23 g/mol
CAS number: 73-22-3
EC number: 200-795-6
Chemical family: Amino acid
Origin: Fermentation-derived or synthetic
CAS: 73-22-3
IUPAC Name: (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
Molecular Formula: C11H12N2O2
InChI Key: QIVBCDIJIAJPQS-VIFPVBQESA-N
SMILES: N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
Molecular Weight (g/mol): 204.23
MDL Number: MFCD00064340
Properties of L-Tryptophane:
Categories: Amino acids,Tryptophane
Assay: 99%+
Appearance (Form): Powder
Appearance (Colour): White to off white
Melting point: 280-285 °C
Loss on drying (105° C): 0.5% max
Appearance: White to slightly yellow crystalline powder
Odor: Odorless
Taste: Slightly bitter
Physical state: Solid
Solubility: Slightly soluble in water
Melting point: ~280–290°C (decomposes)
pH: Slightly acidic in solution
Stability: Stable under normal conditions, sensitive to light
Molecular Weight: 204.22 g/mol
XLogP3: -1.1
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 3
Exact Mass: 204.089877630 Da
Topological Polar Surface Area: 79.1 Ų
Heavy Atom Count: 15
Complexity: 245
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Specifications of L-Tryptophane:
Appearance (Color): White to pale cream
Form: Crystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration): ≥98.5% to ≤101.5%
Assay from Suppliers CofA: ≥98.5%
Identification (FTIR): Conforms
Optical Rotation: -29.0° to -33.0° (c= 1 in Water)