Quick Search
LIGAMED MF-2-K-MB is produced in accordance with strict Kosher and Halal regulations and offer the respective certifications.
These certificates are required for OTC pharmaceutical and nutraceutical preparations in Jewish and Arab cultures.
Kosher and Halal certification has also become an important quality standard requested by European formulators.
CAS: 557-04-0
MF: C36H70MgO4
MW: 591.24
EINECS: 209-150-3
Synonyms
stearatedemagnesium;MAGNESIUM STEARATE;MAGNESIUM OCTADECANOATE;MAGENSIUM STEARATE;STEARIC ACID MAGNESIUM SALT;OCTADECONIC ACID MAGNESIUM SALT;OCTADECANOIC ACID MAGNESIUM SALT;Magnesium Stearate Bp
LIGAMED MF-2-K-MB, also called octa decanoic acid, magnesium salt, is a white substance, powder which becomes solid at room temperature.
LIGAMED MF-2-K-MB has the chemical formula Mg(C18H35O2)2.
LIGAMED MF-2-K-MB is a salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg2+).
LIGAMED MF-2-K-MB melts at about 120 °C, is not soluble in water, and is generally considered safe for human consumption at levels below 2500 mg/kg per day.
In 1979, the FDA's Subcommittee on GRAS (generally recognized as safe) Substances (SCOGS) reported, "There is no evidence in the available information on ... magnesium stearate ... that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current and in the manner now practiced, or which might reasonably be expected in the future.".
LIGAMED MF-2-K-MB Chemical Properties
Melting point: 200 °C (lit.)
density: 1.028g/cm3
storage temp.: Inert atmosphere,Room Temperature
solubility alcohol: insoluble
form: Fine Powder
color: White
PH: 7 (H2O) (slurry)
Odor: wh. soft oily powd., tasteless, odorless
Water Solubility: Insoluble
Merck: 14,5690
BRN: 3919702
Exposure limits ACGIH: TWA 10 mg/m3; TWA 3 mg/m3
Stability: Stable. Incompatible with strong oxidizing agents.
Major Application: pharmaceutical (small molecule)
Cosmetics Ingredients Functions: MOISTURISING
ANTICAKING
BULKING
COLORANT
Cosmetic Ingredient Review (CIR): Magnesium stearate (557-04-0)
InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InChIKey: DRJIJXNWSSRTTE-UHFFFAOYSA-M
LogP: 8.216 (est)
CAS DataBase Reference: 557-04-0(CAS DataBase Reference)
EPA Substance Registry System: LIGAMED MF-2-K-MB (557-04-0)
LIGAMED MF-2-K-MB is a kind of fatty acid salt type anionic surfactant with its appearance being white powder with slight special smell and creamy feeling.
LIGAMED MF-2-K-MB can be soluble in hot aliphatic hydrocarbons, hot arene and hot grease but insoluble in alcohol and water with being decomposed into stearic acid and corresponding magnesium salts in case of
LIGAMED MF-2-K-MB has an excellent adhesion property to the skin with excellent lubrication property.
LIGAMED MF-2-K-MB can be applied to powder products in cosmetics and can improve adhesion and lubrication.
LIGAMED MF-2-K-MB can be used as PVC heating stabilizers with the stability performance being similar to calcium stearate and can be combined with zinc or calcium soaps for being applied to food packaging material but without very wide application.
LIGAMED MF-2-K-MB can be used as a mold releasing agent of plastic products, face powder of cosmetics, the raw material of skin ointment, the powder molding tablet of pharmaceutical tablets and translucent flatting agent of paint.
Laboratory, through the replacement reaction of sodium stearate and magnesium sulfate, is able to get finished product of LIGAMED MF-2-K-MB and can also apply the combination reaction between edible solid organic acids (stearic acid, palmitic acid) mixture and magnesium oxide compounds and further refinement to make it.
Uses
LIGAMED MF-2-K-MB has been widely used for many decades in the food industry as an emulsifier, binder and thickener, as well as an anticaking, lubricant, release, and antifoaming agent.
LIGAMED MF-2-K-MB is present in many food supplements, confectionery, chewing gum, herbs and spices, and baking ingredients.
LIGAMED MF-2-K-MB is also commonly used as an inactive ingredient in the production of pharmaceutical tablets, capsules and powders.
The main reason for its good lubricating properties is its hydrophobic nature and an ability to reduce friction between tablets and die wall during the ejection process.
LIGAMED MF-2-K-MB can be regarded as being non-toxic, the United States, Germany and Japan allow it to be applied to products being contact with food.
However, LIGAMED MF-2-K-MB doesn’t have wide application to be applied as PVC heat stabilizers.
In China and some other countries Pharmacopoeia, there are always records of this specie. The pharmacopeia has also made provisions on the magnesium content, moisture, heavy metals, iron, sulfate and chloride content.
Production method
LIGAMED MF-2-K-MB is produced by the reaction of sodium stearate with magnesium salts or by treating magnesium oxide with stearic acid (Nora 2005).
LIGAMED MF-2-K-MB can be produced through the following procedure: first get the sodium stearate through the saponification between stearic acid and sodium; then the sodium stearate has double decomposition reaction with magnesium sulfate to get the finished product.
Stearic acid and water was added to the reaction pot and heated to 85 ℃, stirring to dissolve, slowly add them to the sodium hydroxide solution preheated to 75 ℃.
After the saponification reaction was completed, the temperature was controlled at 72 ℃ and slowly added to the magnesium sulfate solution preheated to 55 ℃ upon stirring.
After metathesis, apply centrifuge to remove the water.
The filtering cake was washed with water until sulfate ion requirement is met, then dry, apply air drying, sifting to obtain the finished products with the yield of stearic acid being 100%.
LIGAMED MF-2-K-MB is produced through the combination reaction between magnesium oxide and food grade solid mixed fatty acids (mainly stearic acid) and further refinement.
