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CAS NUMBER: 554-13-2
EC NUMBER: 209-062-5
MOLECULAR FORMULA: Li2CO3
MOLECULAR WEIGHT: 73.89
Lithium carbonate is an inorganic compound, the lithium salt of carbonate with the formula Li2CO3.
Lithium carbonate appears as a white powder.
Strong irritant when dissolved in water.
Lithium carbonate is widely used in the processing of metal oxides, and as a drug for the treatment of mood disorders.
For the treatment of bipolar disorder, Lithium carbonate is on the World Health Organization's List of Essential Medicines, Lithium Carbonate should not be combined with alcoholics health system.
Lithium Carbonate is a prescription medicine used to treat the symptoms of Bipolar Disorder.
Lithium Carbonate may be used alone or with other medications.
Lithium Carbonate belongs to a class of drugs called Bipolar Disorder Agents.
Lithium carbonate is not known if Lithium Carbonate is safe and effective in children younger than 7 years of age.
Lithium Carbonate is the carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities.
Lithium interferes with transmembrane sodium exchange in nerve cells by affecting sodium, potassium-stimulated adenosine triphosphatase (Na+, K+-ATPase); alters the release of neurotransmitters; affects cyclic adenosine monophosphate (cAMP) concentrations; and blocks inositol metabolism resulting in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. The exact mechanism through which lithium exerts its mood-stabilizing effect has not been established. In addition, lithium stimulates granulocytopoiesis and appears to increase the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines and/or directly acting on hematopoietic stem cells.
Lithium carbonate appears as a white powder.
Strong irritant when dissolved in water.
Lithium carbonate is a lithium salt and a carbonate salt.
Lithium carbonate has a role as an antimanic drug.
Lithium carbonate and some other lithium salts are used for the treatment of some psychiatric illnesses, particularly bipolar mood disorders.
Lithium carbonate is estimated that between 0.5 and 1.5% of women are affected by bipolar disorder, and typical onset is during reproductive years.
Lithium carbonates the placenta, and maternal and fetal blood and tissue levels may be similar.
Lithium carbonate has been used to treat manic episodes since the 19th century3.
Though Lithium carbonate is widely used, its mechanism of action is still unknown Label.
Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effectsLabel.
Lithium carbonate is a widely used and invaluable drug in the treatment and prevention of manic-depressive illness.
Lithium carbonate has a low therapeutic index and, therefore, many attendant side effects.
Lithium carbonate affects predominantly the central nervous system and the renal system and is potentially lethal.
We studied a case of acute lithium carbonate intoxication characterized by a prolonged comatose state, severe nephrogenic diabetes insipidus, and glucose intolerance.
Lithium carbonate (Li2CO3), a lithium salt, is a white monoclinic crystalline solid.
Lithium carbonates industrial preparation has been described.
In laboratory, Lithium carbonate can be synthesized by reacting carbon dioxide gas with a lithium hydroxide solution.
Lithium Carbonate is a water insoluble Lithium source that can easily be converted to other Lithium compounds, such as the oxide by heating (calcination).
Lithium carbonate compounds also give off carbon dioxide when treated with dilute acids.
Lithium Carbonate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
Lithium carbonate is one of the most important products in lithium industry.
Lithium carbonate can be widely used in the manufacture of most lithium-ion battery cathodes, add-in materials to ceramic or glass, pharmaceutical agent for bipolar disorder and raw materials to produce other lithium compounds.
These applications put different requirements for morphology and size distribution of lithium carbonate crystals.
For example, agglomeration effect, which can result in low purity, is undesirable in the production of battery-grade lithium carbonate; nevertheless, it can be favorable to improve the flowability and compressibility by producing lithium carbonate spherulite product.
Most attention has been paid to the study of its high-quality and well-sized single-crystal morphology under low supersaturation, (3−6) while few studies have been focused on its agglomeration phenomenon under high supersaturation. However, when it comes to industrial production, low supersaturation is not cost-effective and the production of lLithium carbonate needs to be under slightly higher supersaturation.
In this work, emphasis has been put on the crystal agglomeration of lithium carbonate under high supersaturation.
Lithium carbonate is a mood stabilizer; thought to act by reducing catecholamine neurotransmitter concentration, through an effect on the Na+/K+ ATPase pump.
Lithium carbonate is used in various industries, such as electronics, ceramics, glass, etc.
Due to Lithium carbonates high electrochemical potential and being the lightest solid element, its main use is as a cathode material in lithium ion batteries.
Lithium carbonate is found naturally as the mineral zabuyelite, first found in 1987 by the Tibetan lake Zabuye, but this is fairly rare.
Fortunately, Lithium carbonate is easy enough to make from more readily available compounds, typically from lithium chloride which is found in mineral springs and pools, particularly.
Lithium Carbonate is a primary product in the Lithium manufacturing supply chain and is used to make many downstream Lithium chemicals.
Glass and ceramic industries use Lithium carbonate to lower melting points and prevent expansion in enamels, glazes and high temperature glass.
In the construction industry Lithium carbonate is used as an accelerant in cements where particle size determines its performance.
Battery grade Lithium Carbonate has found a new application in the cathode of Lithium-ion batteries where the impurities and particle size need to be closely controlled.
Lithium Carbonate is the best source of lithium oxide for glazes.
Lithium carbonate is slightly soluble.
Lithium carbonate is unusual to see more than 5% lithium carbonate in glaze.
Because of the low expansion of Lithium carbonate, high lithium glazes tend to shiver.
There are certain basic properties of Lithium carbonate which are of interest in ceramics.
Since Lithium carbonate has a very small ionic radius in comparison to the other alkali metals, it has a higher field strength.
Low expansion coefficients are generally imparted to ceramic compositions containing lithia.
Lithium carbonate is a very strong flux (also true of lithium fluoride).
In contrast, other lithium compounds may be quite refractory: lithium zirconate and lithium aluminum spinel are examples.
There is comparatively little published information on the use of lithia compounds in ceramics.
Laboratory investigations indicate that small additions of lithium will react with quartz during firing and eliminate the alpha-beta quartz transition in the cooling cycle.
Lithia imparts low thermal expansion coefficients to glasses and also promotes devitrification in glass systems.
Smaller amounts act to smooth the glass surface.
Lithium carbonate exhibits many properties that are similar to the more common alkali metals sodium and potassium.
In many respects is also shows similarities to the elements of the alkaline earth group, especially magnesium.
In addition to being soluble, lithium carbonate produces gases as it decomposes and these can cause pinholes or blisters in glazes.
There are insoluble lithium frits available (e.g. Fusion F-493 has 11%) and incorporating one of them to source the Lithium carbonate instead is a classic application of glaze chemistry calculations (however for glazes with very high amounts of lithium, like 10%+, it will be difficult to source the Li2O using a frit because significant amounts will be required and this will likely oversupply the other oxides the frit brings).
The resultant glaze will be more fusible and will have better clarity and fewer defects.
Lithium carbonate is a lithium-based compound that has been used for decades in various industries, including medical sector.
This inorganic carbonate is one of the most widely used intermediary chemicals in the lithium industry, together with lithium hydroxide.
USES:
Lithium carbonate is an important industrial chemical.
Lithium carbonates main use is as a precursor for compounds used in lithium-ion batteries.
Glasses derived from lithium carbonate are useful in ovenware.
Lithium carbonate is a common ingredient in both low-fire and high-fire ceramic glaze.
Lithium carbonate forms low-melting fluxes with silica and other materials.
Lithium carbonates alkaline properties are conducive to changing the state of metal oxide colorants in glaze particularly red iron oxide.
Cement sets more rapidly when prepared with lithium carbonate, and is useful for tile adhesives.
When added to aluminium trifluoride, Lithium carbonate forms LiF which gives a superior electrolyte for the processing of aluminium.
Lithium carbonate is used for lithium iron phosphate (LFP)batteries.
Lithium carbonate and other alkali metal carbonates are used to produce carbon dioxide detectors, which are potentially life-saving devices, but also widely used in the industrial world.
The lithium carbonate reacts with carbon dioxide, changing the reactions in a detection electrode, which can trigger a warning.
-Rechargeable batteries:
The main use of lithium carbonate (and lithium hydroxide) is as a precursor to lithium compounds used in lithium-ion batteries.
In practice two components of the battery are made with lithium compounds: the cathode and the electrolyte.
The electrolyte is a solution of lithium hexafluorophosphate, while the cathode uses one of several lithiated structures, the most popular of which are lithium cobalt oxide and lithium iron phosphate.
Lithium carbonate may be converted into lithium hydroxide before conversion to the compounds above.
-Medical uses:
This finding led Lithium carbonate, specifically lithium carbonate, to be used to treat mania associated with bipolar disorder.
Lithium carbonate is used as a psychiatric medication to treat mania, the elevated phase of bipolar disorder.
Lithium carbonate ions interfere with ion transport processes (see “sodium pump”) that relay and amplify messages carried to the cells of the brain.
Lithium carbonate and sodium valproate, another drug traditionally used to treat the disorder, act in the brain by inhibiting PKC's activity and help to produce other compounds that also inhibit the PKC.
Lithium carbonate's mood-controlling properties are not fully understood.
-Adverse reactions:
Extended use of lithium to treat various mental disorders has been known to lead to acquired nephrogenic diabetes insipidus.
Lithium carbonate can affect the central nervous system and renal system and can be lethal.
-Red pyrotechnic colorant:
Lithium carbonate is used to impart a red color to fireworks.
APPLICATION:
Lithium carbonate (Li2CO3) may be used in the following studies:
-As a precursor in the preparation of LiFe1-yVyPO4 solid solutions.
-As a starting reagent for the synthesis of various lithium salts (lithium chloride and lithium bromide).
PROPERTIES:
Unlike sodium carbonate, which forms at least three hydrates, lithium carbonate exists only in the anhydrous form.
Lithium carbonates solubility in water is low relative to other lithium salts.
The isolation of lithium from aqueous extracts of Lithium carbonate ores capitalizes on this poor solubility.
Lithium carbonates apparent solubility increases 10-fold under a mild pressure of carbon dioxide.
The extraction of lithium carbonate at high pressures of CO2 and its precipitation upon depressurizing is the basis of the Quebec process.
Lithium carbonate can also be purified by exploiting its diminished solubility in hot water.
Thus, heating a saturated aqueous solution causes crystallization of Li2CO3.
Lithium carbonate, and other carbonates of group 1, do not decarboxylate readily.
Lithium carbonate decomposes at temperatures around 1300 °C.
PROPERTIES:
-Quality Level: 200
-grade: ACS reagent, reagent (for microscopy), puriss. p.a.
-assay: ≥99.0% (T)
-form: powder
-pH: 9-11 (1 g/L)
-mp: 618 °C (lit.)
SPECIFICATIONS:
-Compound Formula: CLi2O3
-Molecular Weight: 73.9
-Appearance: White powder
-Melting Point: 618-723 °C
-Boiling Point: 1310 °C (dec.)
-Density: 2.11 g/cm3
-Solubility in H2O: 1.29 g/100 mL (25 °C)
-Refractive Index: 1.428
-Specific Heat: 97.4 J/mol·K
-Exact Mass: 74.016752
-Monoisotopic Mass: 74.016754 Da
CHEMICAL IDENTIFIERS:
-Linear Formula: Li2CO3
-MDL Number: MFCD00011084
-EC No.: 209-062-5
-Beilstein/Reaxys No.: 3999191
-Pubchem CID: 11125
-IUPAC Name: dilithium carbonate
-SMILES: [Li+].[Li+].[O-]C([O-])=O
-InchI Identifier: InChI=1S/CH2O3-C.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
-nchI Key: XGZVUEUWXADBQD-UHFFFAOYSA-L
CHEMICAL PROPERTIES:
Lithium carbonate is a salt of lithium most used and it is widely commercialized to the bipolarity treatment.
Lithium carbonate is the ion most similar to sodium, by size and charge, thus it is a competitor of sodium in the transmembrane exchange in nerve cells, thus it can be affected the release of neurotransmitters.
Lithium carbonate can also be used to elevate the peripheral leukocytes.
PHYSICAL PROPERTIES:
Lithium carbonate is an odorless white powder.
Lithium carbonates density is 2.11 g mL-1.
Lithium carbonate melting point is 724 ºC and its boiling point is 1310 ºC.
Lithium carbonate is insoluble in hot water, acetone, ammonia and ethanol.
Lithium carbonate is poorly soluble in cold water (its solubility in water decrease with the increasing the temperature).
Lithium carbonate is soluble in acetic acid.
SYNONYM:
554-13-2
Dilithium carbonate
Lithonate
Lithobid
Lithane
Carbonic acid, dilithium salt
Eskalith
Lithotabs
Carbonic acid lithium salt
Liskonum
Lithizine
Micalith
Priadel
Limas
Eskalith CR
Camcolit
Neurolepsin
Candamide
Carbolith
Eutimin
Hypnorex
Lithicarb
Lithinate
Lithionate
Liticar
Manialith
Maniprex
Litard
Lithea
Plenur
Quilonum retard
Pfi-lithium
Lithium Phasal
Pfl-Lithium
Litho-Carb
NSC-16895
Carbolithium
UNII-2BMD2GNA4V
CP-15467-61
Lithium carbonate (Li2CO3)
MFCD00011084
2BMD2GNA4V
CHEBI:6504
Carbonic acid lithium salt (Li2CO3)
Lithium carbonate (2:1)
CP-15,467-61
Carbonic acid, lithium salt (1:2)
CP 15467-61
Ceglution
Phasal
Teralithe
Lithium Carbonate Nanoparticles
Lithium carbonate, 99%, pure
Teralithe
Lithium, Reference Standard Solution
Lithium carbonicum
Li2 (C O3)
Lithium carbonate, 98+%, for analysis
Lithium carbonate, 99+%, ACS reagent
Carbonic Acid Dilithium Salt
CCRIS 3153
HSDB 3351
EINECS 209-062-5
Lithium carbonate, 99.999%, (trace metal basis), extra pure
Carbolithium IFI
Lithium QD
Eskalith (TN)
Lithobid (TN)
Lithium carbonate [USAN:USP:JAN]
ACMC-209lmw
Lithium Carbonate Powder
CLi2O3
Li2CO3
dilithium trioxidocarbonate
EC 209-062-5
CHEMBL1200826
DTXSID1023784
Lithium carbonate (JP17/USP)
ANW-32310
Lithium carbonate, ACS reagent grade
AKOS015904647
ANGC-554-13-2
DB14509
I494
B7705
CP-1546761
FT-0627895
L0224
D00801
Dilithium Carbonate, Dilithium Salt, Carbonic Acid
Q410174
IUPAC NAME:
Carbonato de litio
CARBONIC ACID, DILITHIUM SALT
Dilithium carbonate
dilithium carbonate
dilithium(1+) carbonate
dilithium(1+) ion carbonate
dilithium;carbonate
Lithium Carbnate
LITHIUM CARBONATE
Lithium Carbonate
Lithium carbonate
lithium carbonate
Lithium carbonate
lithium carbonate
Lithium Carbonate
