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Mono-n-propylamine is a member of the class of alkylamines that is propane substituted by an amino group at C-1.
Mono-n-propylamine is a conjugate base of a propan-1-aminium.
A clear colorless liquid with an ammonia-like odor.
CAS: 107-10-8
MF: C3H9N
MW: 59.11
EINECS: 203-462-3
Synonyms
1-Aminopropan;1-Amino-propan;1-Propylamine;Monopropylamine;n-C3H7NH2;Propanamine;Propylamin;n-Propylaminwe
Flash point -35°F. Less dense than water and soluble in water.
Vapors are heavier than air.
Produces toxic oxides of nitrogen during combustion.
Used in chemical analysis and to make other chemicals.
Mono-n-propylamine also known as n-propylamine, is an amine with the chemical formula CH3(CH2)2NH2.
Mono-n-propylamine is a colorless volatile liquid.
Mono-n-propylamine is a weak base.
Mono-n-propylamine's Kb (base dissociation constant) is 4.7 × 10−4.
Mono-n-propylamine (MNPA) also known as Propylamine, is a clear colorless liquid with an ammonia-like odor.
Mono-n-propylamine is miscible with water, alcohol and ether.
Mono-n-propylamine Chemical Properties
Melting point: -83 °C (lit.)
Boiling point: 48 °C (lit.)
Density: 0.719 g/mL at 25 °C (lit.)
Vapor density: 2 (vs air)
Vapor pressure: 4.79 psi ( 20 °C)
Refractive index: n20/D 1.388(lit.)
FEMA: 4237 | PROPYLAMINE
Fp: −35 °F
Storage temp.: Store below +30°C.
Solubility water: soluble0.4 part(lit.)
pka: 10.6(at 20℃)
Form: Liquid
Specific Gravity: 0.7173
Color: Clear colorless to pale yellow
PH: 12.6 (100g/l, H2O, 20℃)
Odor: ammoniacal
Odor Type: ammoniacal
Biological source: human blood
Odor Threshold: 0.061ppm
Explosive limit: 2.1-13.6%(V)
Water Solubility: soluble
Sensitive: Air Sensitive
JECFA Number: 1580
Merck: 14,7843
BRN: 1098243
Exposure limits: No exposure limit has been set. Based on its similarity to ethylamine in irritation and toxicity, a TLV-TWA of 10 ppm (～24 mg/m3) should be appropriate. .
Dielectric constant: 5.9000000000000004
Dielectric constant: 3.0（Ambient）
Stability: Stable. Highly flammable. Note low flash point. Readily forms explosive mixtures with air. Incompatible with oxidising agents, strong acids. Store cool.
LogP: 0.55
CAS DataBase Reference: 107-10-8(CAS DataBase Reference)
NIST Chemistry Reference: Mono-n-propylamine(107-10-8)
EPA Substance Registry System: Mono-n-propylamine (107-10-8)
Mono-n-propylamine, also known as propylamine, is a colorless liquid with a pungent odor resembling ammonia.
Mono-n-propylamine has strong basic properties, leading to its easy formation of salts when combined with acids.
Mono-n-propylamine's reactivity is similar to that described for the other short chain aliphatic amines.
Uses
Mono-n-propylamine is used in chemical analysis and to make other chemicals, used as a solvent in organic synthesis. And it is used as finishing agent of drugs, paints, rubber, fiber, textile and resin.
Additionally, Mono-n-propylamine can be used as petroleum additive and preservative.
Mono-n-propylamine is used as an intermediate inmany organic reactions.
Mono-n-propylamine has been used in the synthesis of single crystals of siliceous ferrierite.
Industrial uses
Mono-n-propylamine is important as a chemical intermediate for rubber chemicals, dyestuffs, propyl isocyanate, textile and leather finishing resins and corrosion inhibitors.
Mono-n-propylamine is also used in the production of pharmaceuticals such as Prilocaine, pesticides including Profluralin and in petroleum additives.
In 1976, 500 tons of Mono-n-propylamine were manufactured in the U.S.
Production Methods
There are several methods employed in the manufacture of propylamine.
Typically, ammonia and propanol are reacted over a dehydration catalyst at high temperature and pressure.
Ammonia, propanol, and hydrogen can also be reacted over a dehydrogenation catalyst such as metallic silver.
Mono-n-propylamine can also be synthesized from propionaldehyde and ammonia with a Raney nickel catalyst.
Mono-n-propylamine can be prepared by reacting 1-propanol with ammonium chloride at high temperature and pressure using a Lewis acid catalyst such as ferric chloride.
Reactivity Profile
Colorless, alkaline liquid, very volatile (b. p. 48° C), moderately toxic, highly flammable. Dangerous fire hazard when exposed to heat, flame, sparks, or strong oxidizers.
When heated to decomposition Propylamine emits toxic fumes of oxides of nitrogen. Incompatible with triethylaluminum, complex may explode on sublimation.
Health Hazard
Mono-n-propylamine is a strong irritant and a mod erately toxic substance.
the toxic routes areinhalation, ingestion, and absorption throughthe skin.
Contact of the liquid on the skincan cause burns and possibly skin sensitization.
Irritation in the eyes from exposure tohigh concentrations can be severe.
Mono-n-propylamine is a respiratory tract irritant, similar to ethylamine.
Inhalation of 2300 ppm of n-propylamine for4 hours caused labored breathing, hepatitis,and hepatocellular necrosis in rats.
Mono-n-propylamine is somewhat less toxic than ethylamine by oral anddermal routes.
