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ORTHO BORIC ACID

Ortho Boric Acid is used as a flux in metal soldering.
Ortho Boric Acid is used as a preservative against wood rot.
Ortho Boric Acid is used as an alkalizing agent in pharmaceuticals.


CAS Number: 10043-35-3 
EC Number: 233-139-2
MDL number: MFCD00011337
E number: E284 (preservatives)
Chemical formula: BH3O3
Molecular Formula: BH3O3 / H3BO3 / B(OH)3

SYNONYMS:
BORATE BUFFER, Boric acid flakes, boric, TBE BUFFER, Boricacid,99.8%, Boric acid (H3BO3), TRIS-BORATE-EDTA, boric acid solution, BORIC ACID GRANULAR, Boric Acid, Powder, Reagent, Boric acid, Orthoboric acid, Boracic acid, Sassolite, Borofax, Trihydroxyborane, Boranetriol, Hydrogen borate, Acidum boricum, BORIC ACID, Orthoboric acid, 10043-35-3, Boracic acid, Borofax, Boron hydroxide, Boron trihydroxide, Boric acid (H3BO3), Basilit B, Boric acid (BH3O3), 11113-50-1, Trihydroxyborone, Orthoborsaeure, Borsaeure, Borsaure, Trihydroxyborane, Orthoboric acid (B(OH)3), Optibor, Acidum boricum, NCI-C56417, component of Aci-Jel, Boric acid (VAN), Bluboro, Boricum acidum, Caswell No. 109, trihydroxidoboron, Boric acid flakes, B(OH)3, CCRIS 855, NSC 81726, HSDB 1432, Orthoboric acid (H3BO3), EINECS 233-139-2, UNII-R57ZHV85D4, MFCD00011337, NSC-81726, Boric acid (TN), EPA Pesticide Chemical Code 011001, INS NO.284, R57ZHV85D4, CHEBI:33118, AI3-02406, INS-284, (10B)Orthoboric acid, Boric acid (h(sub 3)bo(sub 3)), H3BO3, DTXSID1020194, E-284, EC 233-139-2, [B(OH)3], NSC81726, NCGC00090745-02, BORIC ACID (II), BORIC ACID [II], Orthboric Acid, BORIC ACID (MART.), BORIC ACID [MART.], BORIC ACID (USP-RS), BORIC ACID [USP-RS], DTXCID10194, BORIC ACID (EP IMPURITY), BORIC ACID [EP IMPURITY], BORIC ACID (EP MONOGRAPH), BORIC ACID [EP MONOGRAPH], (B(OH)3), ortho-boric acid, Boric acid [USAN:JAN], hydrogen orthoborate, BO3, CAS-10043-35-3, Boric acid [JAN:NF], BORIC ACID, ACS, Canagyn, acido borico, Orthoborc acd, The Killer, Boric acid, V-Bella, HYLAFEM, Bluboro (Salt/Mix), Homeopathic Antifungal, Boric acid ACS grade, GYNOX-SOFT, Boric acid, Puratronic?, WLN: QBQQ, BORIC ACID [MI], Boric acid, ACS reagent, BORIC ACID [JAN], Heptaoxotetra-Borate(2-), bmse000941, Boric acid (JP15/NF), Boric acid (JP17/NF), BORIC ACID [INCI], Acidum boricum (Salt/Mix), BORIC ACID [VANDF], Boric acid, NF/USP grade, BORIC ACID [WHO-DD], Boric acid, biochemical grade, BIDD:ER0252, Boric Acid, BORICUM ACIDUM [HPUS], CHEMBL42403, BORIC ACID (B(OH)3), Boric acid Electrophoresis grade, Collyrium Eye Wash (Salt/Mix), HYLAFEMBORICUM ACIDUM 3X, BDBM39817, KGBXLFKZBHKPEV-UHFFFAOYSA-, Boric acid, 99.9% metals basis, BCP21018, Boric acid, 99.99% metals basis, Boric acid, BioXtra, >=99.5%, EINECS 237-478-7, Tox21_111004, Tox21_202185, Tox21_301000, 1332-77-0 (di-potassium salt), MFCD00151271, Boric acid, 99.998% metals basis, AKOS015833571, Boric acid, ACS reagent, >=99.5%, DB11326, USEPA/OPP Pesticide Code: 011001, Boric acid, 99.97% trace metals basis, Boric acid, USP, 99.5-100.5%, NCGC00090745-01, NCGC00090745-03, NCGC00090745-04, NCGC00090745-05, NCGC00254902-01, NCGC00259734-01, Boric acid, ReagentPlus(R), >=99.5%, BP-13473, SY319258, Boric acid, 99.999% trace metals basis, Boric acid, SAJ first grade, >=99.5%, Boric acid, for electrophoresis, >=99.5%, Boric acid, JIS special grade, >=99.5%, Boric acid, Vetec(TM) reagent grade, 98%, InChI=1/BH3O3/c2-1(3)4/h2-4H, NS00013411, Boric acid, tablet, 1 g boric acid per tablet, D01089, A800201, Q187045, J-000132, J-523836, Boric acid, >=99.5%, suitable for amino acid analysis, Boric acid, NIST(R) SRM(R) 951a, isotopic standard, Boric acid, NIST(R) SRM(R) 973, acidimetric standard, Boric acid, BioUltra, for molecular biology, >=99.5% (T), Boric acid, United States Pharmacopeia (USP) Reference Standard, Boric acid, cell culture tested, plant cell culture tested, >=99.5%, Boric acid, Biotechnology Performance Certified, >=99.5% (titration), Cell Culture Tested, Boric acid, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.5-100.5%, Boric acid, BioReagent, for molecular biology, suitable for cell culture, suitable for plant cell culture, >=99.5%, Boric acid, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., buffer substance, >=99.8%, Boric acid, puriss., meets analytical specification of Ph. Eur., BP, NF, 99.5-100.5%, powder, orthoboric acid, boracic acid, borofax, boron hydroxide, boron trihydroxide, basilit b, trihydroxyborone, h3bo3, flea prufe, 11113-50-1, Boric acid, Boracic acid, Orthoboric acid, H3-BO3, Boracic acid, Boric acid (BH3O3), Boric acid (H3BO3), Borofax, Boron hydroxide, Boron trihydroxide, NCI-C56417, Orthoboric acid (B(OH)3), Borsaure, B(OH)3, Basilit B, Orthoboric acid, H3-BO3, Boracic acid, Boric acid (BH3O3), Boric acid (H3BO3), Borofax, Boron hydroxide, Boron trihydroxide, NCI-C56417, Orthoboric acid (B(OH)3), Borsaure, Three elephant, Ant flip, Homberg's salt, B(OH)3, Basilit B, Dr.'s 1 Flea Terminator DF, Dr.'s 1 Flea Terminator DFPBO, Dr.'s 1 Flea Terminator DT, Dr.'s 1 Flea Terminator DTPBO, Flea Prufe, NSC 81726, Super Flea Eliminator, Trihydroxyborane, Acidum boricum (Salt/Mix), Bluboro (Salt/Mix), Collyrium Eye Wash (Salt/Mix), Collyrium Fresh-Eye Drops (Salt/Mix), component of Aci-Jel (Salt/Mix), Orthoboric Acid, Boron Hydroxide, Boron Trihydroxide, Homberg Salt, Eye Wash Chemical,

Ortho Boric Acid is a white, amorphous powder orcolorless, crystalline solid. 
Ortho Boric Acid is a weakly acidic hydrate of boric oxide with mild antiseptic, antifungal, and antiviral properties.
Ortho Boric Acid is soluble in water; solubility=4.7 g/100 mL at20℃.


Ortho Boric Acid, white powder crystal or triclinic axial surface scaly luster crystal, have greasy feel, no smell.
Ortho Boric Acid is widely used in glass (optical glass, acid-proof glass, heat-resistant glass, fiberglass for insulating materials) industry, which can improve the heat-resistant and transparent performance of glass products, improve the mechanical strength and shorten the melting time.


Ortho Boric Acid (orthoboric-acid) is a weakly acidic hydrate of boric oxide with mild antiseptic, antifungal, and antiviral properties.
Ortho Boric Acid is naturally occurring compound of Boron. 
Ortho Boric Acid occurs in minerals borax, boracite, boron atrocaicite and colemanite. 


Ortho Boric Acid is also found in seawater, plants and in fruits.
Ortho Boric Acid, H3BO3 is a white crystalline solid, with soapy touch. 
Ortho Boric Acid is sparingly soluble in water but highly soluble in hot water.


Ortho Boric Acid is soluble in water, alcohol, glycerin, ethers and essential oils, the aqueous solution is weakly acidic.
Ortho Boric Acid is an odorless white solid. 
Melting point of Ortho Boric Acid is 171 °C. 


Ortho Boric Acid sinks and mixes with water. 
Ortho Boric Acid is a member of boric acids. 
Ortho Boric Acid has a role as an astringent. 


Ortho Boric Acid  is a conjugate acid of a dihydrogenborate.
Ortho Boric Acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. 
Ortho Boric Acid is a weakly acidic hydrate of boric oxide with mild antiseptic, antifungal, and antiviral properties. 


The exact mechanism of action of Ortho Boric Acid is unknown; generally cytotoxic to all cells. 
Ortho Boric Acid is used in the treatment of yeast infections and cold sores.
Ortho Boric Acid is a small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 4 investigational indications.


Ortho Boric Acid (H3BO3) also called hydrogen borate, boracic acid, Ortho Boric Acid is a weak acid of boron often used as an antiseptic, insecticide, flame retardant, neutron absorber, or precursor to other chemical compounds. 
Ortho Boric Acid has the chemical formula H3BO3 (sometimes written B(OH)3), and exists in the form of colorless crystals or a white powder that dissolves in water. 


When occurring as a mineral, Ortho Boric Acid is called sassolite. 
Borate is a food contaminant deriving from paper and paperboard in contact with food. 
Ortho Boric Acid has limited use as an antibacterial agent in caviar.


Ortho Boric Acid, more specifically Ortho Boric Acid, is a compound of boron, oxygen, and hydrogen with formula B(OH)3. 
Ortho Boric Acid may also be called hydrogen orthoborate, trihydroxidoboron or boracic acid.
Ortho Boric Acid is usually encountered as colorless crystals or a white powder, that dissolves in water, and occurs in nature as the mineral sassolite. 


Ortho Boric Acid is a weak acid that yields various borate anions and salts, and can react with alcohols to form borate esters.
Ortho Boric Acid, more commonly known as just boric acid, is a weak, monobasic Lewis acid of boron. 
Ortho Boric Acid is an odourless and naturally occurring powder in its original form. 


Ortho Boric Acid is found mainly in its free state in some volcanic areas.
Ortho Boric Acid is also found as a constituent of many naturally occurring minerals such as boracite, borax, colemanite and ulexite (boronatrocalcite). 
Alternatively, Ortho Boric Acid and its salts are found in seawater.


Ortho Boric Acid is also present in different types of fruits.
The first synthesis of Ortho Boric Acid was performed by Wilhelm Homberg. 
He used borax, and with the action of mineral acids, he synthesised the compound. 


Interestingly, if you look at history, the use of borates and boric acid by the ancient Greeks can be seen. 
Ortho Boric Acid was used mainly for preserving food and cleaning.
Ortho Boric Acid is a weak monobasic acid, it accepts OH- ions, hence is a Lewis acid. 


In Ortho Boric Acid, B is sp2 hybridized, forming a planar triangle structure. 
The principal oxide of boron, B2O3, is obtained as a vitreous solid by dehydration of Ortho Boric Acid at red heat.
Ortho Boric Acid is a monobasic Lewis acid with the chemical formula H3BO3.


Ortho Boric Acid is an organic active ingredient that contains the naturally occurring element Boron. 
Ortho Boric Acid has been regularly used in the U.S. since 1948 as a natural pest control method to eliminate cockroaches, fleas, ants, and silverfish.


Ortho Boric Acid in its original form is an odorless and natural occurring powder which is believed to be a safer method of pest control compared to other more toxic synthetic chemical insecticides. 


To humans, Ortho Boric Acid’s regarded to be as safe as ordinary table salt. 
However, to most pests, coming into contact with Ortho Boric Acid can be lethal, especially for cockroaches, ants, termites, silverfish and other common household insects.


Ortho Boric Acid is an acid-containing compounds of boron, oxygen, and hydrogen. 
Ortho Boric Acid is also known as acidum boricum, hydrogen borate, boracic acid, and Ortho Boric Acid. 
Ortho Boric Acid is a weak acid and has antiviral, antifungal, and antiseptic properties.


Ortho Boric Acid is soluble in water and does not have any characteristic odour. 
Under standard conditions, Ortho Boric Acid exists either as a colourless crystal or in a white powdery form. 
Ortho Boric Acid can be prepared by reacting borax with hydrochloric acid. 


Ortho Boric Acid can be noted that Wilhelm Homberg was the first person to prepare Ortho Boric Acid from borax.
Ortho Boric Acid and its sodium borate salts are pesticides that we can find in nature and many products. 
Borax is one of the most common products. 


Ortho Boric Acid and its sodium salts each combine boron with other elements in a different way. 
In general, their toxicities each depend on the amount of boron they contain.

USES and APPLICATIONS of ORTHO BORIC ACID:
Some of the common uses of Ortho Boric Acid are as follows:
Ortho Boric Acid is a very important tool in pest control and has been used extensively for a long period of time.
Ortho Boric Acid is used in the manufacture of monofilament fibreglass or heat-resistant boron silicate glasses. 


Ortho Boric Acid is used in the production of glass in LCD flat panel displays.
Ortho Boric Acid is used as a preservative for milk and other food items.
Ortho Boric Acid is used in the medical field as an antiseptic.


Ortho Boric Acid is used in the manufacture of enamels and glazes in pottery.
Ortho Boric Acid is also used in some nuclear power plants as a neutron poison.
In the treatment or prevention of boron deficiencies in plants. 


Boron is commonly used in pyrotechnics for preventing amide-forming reactions between aluminium and nitrates. 
Ortho Boric Acid in small quantities is added to the mixture to neutralise alkaline amides that can react with aluminium. 
Ortho Boric Acid Ortho Boric Acidis also used as a colourant to make fire green. 


External wood can be treated with this acid to prevent fungal and insect attacks.
Ortho Boric Acid is used in electroplating as part of some proprietary formulas.


The primary industrial use of Ortho Boric Acid is in the manufacture of monofilament fiberglass usually referred to as textile fiberglass. 
Textile fiberglass, Ortho Boric Acid is used to reinforce plastics in applications that range from boats, to industrial piping to computer circuit boards.


In the jewelry industry, Ortho Boric Acid is often used in combination with denatured alcohol to reduce surface oxidation and formation of firescale on metals during annealing and soldering operations.
Ortho Boric Acid is used in the manufacture of textile fibreglass


Ortho Boric Acid is used in the production of the flat panel display
Ortho Boric Acid is used to neutralize the active hydrofluoric acid


Ortho Boric Acid is used by blacksmiths as welding flux
Ortho Boric Acid is used in electroplating
Ortho Boric Acid is used in the jewellery industry


Ortho Boric Acid is used in the manufacture of silly putty
Ortho Boric Acid is used as an Insecticidal
Ortho Boric Acid is used as an antiseptic and antibacterial


Ortho Boric Acid is used on carrom boards as a dry lubricant
Ortho Boric Acid is used as a neutron poison in some nuclear plants
Ortho Boric Acid is used to preserve grains like wheat and rice


In the list of the chemical additives that are used for hydraulic fracturing (also known as fracking), it is not uncommon for Ortho Boric Acid to be present. 
Ortho Boric Acid is also used as a cross-linking and gelling agent in combination with guar gum and is known to regulate the viscosity and rheology of the drilling fluid which is pumped at high pressure in wells. 


Furthermore, Ortho Boric Acid is of vital importance to regulate the fluid viscosity that helps to keep the grains of the propping agents suspended for long transport distances in order to keep the cracks in the shales sufficiently open. 
Ortho Boric Acid facilitates the extraction of gas after relieving the hydraulic pressure.


Ortho Boric Acid is used in the production of the glass in LCD flat panel displays.
In electroplating, Ortho Boric Acid is used as part of some proprietary formulas. 
One known formula uses about a 1 to 10 ratio of H3BO3 to NiSO4, a very small portion of sodium lauryl sulfate and a small portion of H2SO4.


The solution of Ortho Boric Acid and borax in 4:5 ratio is used as a fire retarding agent of wood by impregnation.
Ortho Boric Acid is also used in the manufacturing of ramming mass, a fine silica-containing powder used for producing induction furnace linings and ceramics.


Ortho Boric Acid is added to borax for use as welding flux by blacksmiths.
Ortho Boric Acid, in combination with polyvinyl alcohol (PVA) or silicone oil, is used to manufacture Silly Putty.
Ortho Boric Acid is also present in the list of chemical additives used for hydraulic fracturing (fracking) in the Marcellus Shale in Pennsylvania.


Ortho Boric Acid is often used in conjunction with guar gum as cross-linking and gelling agent for controlling the viscosity and the rheology of the fracking fluid injected at high pressure in the well. 
Ortho Boric Acid is important to control the fluid viscosity for keeping in suspension on long transport distances the grains of the propping agents aimed at maintaining the cracks in the shales sufficiently open to facilitate the gas extraction after the hydraulic pressure is relieved.


The rheological properties of borate cross-linked guar gum hydrogel mainly depend on the pH value.
Ortho Boric Acid is used in some expulsion-type electrical fuses as a de-ionization/extinguishing agent.
During an electrical fault in an expulsion-type fuse, a plasma arc is generated by the disintegration and rapid spring-loaded separation of the fusible element, which is typically a specialized metal rod that passes through a compressed mass of Ortho Boric Acid within the fuse assembly. 


The high-temperature plasma causes the Ortho Boric Acid to rapidly decompose into water vapor and boric anhydride, and in-turn, the vaporization products de-ionize the plasma, helping to interrupt the electrical fault
Ortho Boric Acid can be used to treat yeast infections and acne, for eyewash by treating any bacterial infection and soothing inflamed eyes, and as a cleanser, deodorizer, stain remover, disinfectant and mold killer. 


Ortho Boric Acid can be used as a pesticide to control a variety of pests, as a fungicide for citrus, and as an herbicide along rights-of-way. 
Ortho Boric Acid can be used for the manufacture of textile fiberglass, household glass products and the glass used in LCD displays, to reinforce plastics in various products (boats, computer circuit boards and pipes), as a flame retardant, and as a pH buffer agent in plating.


Ortho Boric Acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes. 
Ortho Boric Acid is known to exhibit some antibacterial activity against infections such as bacterial vaginosis and candidiasis.


Ortho Boric Acid is often used as an antiseptic, insecticide, flame retardant, neutron absorber, or precursor to other boron compounds.
The term "Ortho Boric Acid" is also used generically for any oxyacid of boron, such as metaOrtho Boric Acid HBO2 and tetraOrtho Boric Acid H2B4O7.
Ortho Boric Acid is quite popular and used widely as a safe alternative to chemical insecticides for pest control in many parts of the world. 


Ortho Boric Acid is a precursor material for other boron compounds. 
A dilute water solution of Ortho Boric Acid is usually employed as a mild antiseptic and eyewash.
Ortho Boric Acid is too employed in leather manufacture, electroplating, and cosmetics.


Ortho Boric Acid is used for weatherproofing wood and fireproofing fabrics; as a preservative; manufacture of cements, crockery, porcelain, enamels, glass, borates, leather, carpets, hats, soaps, artificial gems; in nickeling baths; cosmetics; printing and dyeing, painting; photography; for impregnating wicks; electric condensers; hardening steel. 


Ortho Boric Acid is also used as insecticide for cockroaches and black carpet beetles.
Ortho Boric Acid can be used to study molecular biology, DNA and RNA purification, biological buffers and molecular biology reagents. 
Ortho Boric Acid has been used to test the toxic effects of boron on growth and antioxidant system parameters of maize (Zea mays L.) roots. 


Ortho Boric Acid has also been used to study the effect of time period after Ortho Boric Acid injection on (10)B absorption in different regions of adult male rat′s brain.
Ortho Boric Acid can be used to treat yeast infections and acne, for eyewash by treating any bacterial infection and soothing inflamed eyes, and as a cleanser, deodorizer, stain remover, disinfectant and mold killer. 


Ortho Boric Acid can be used as a pesticide to control a variety of pests, as a fungicide for citrus, and as an herbicide along rights-of-way. 
Ortho Boric Acid can be used for the manufacture of textile fiberglass, household glass products and the glass used in LCD displays, to reinforce plastics in various products (boats, computer circuit boards and pipes), as a flame retardant, and as a pH buffer agent in plating.


Ortho Boric Acid is used as an insecticide and fungicide.
Ortho Boric Acid is used as a mild antiseptic. 
Ortho Boric Acid solutions used as an eye wash.


Ortho Boric Acid is used as a neutron absorber in nuclear power plants, to slow down the rate of fission reaction.
Ortho Boric Acid is used as a lubricant on ceramic or metal surfaces.
Ortho Boric Acid is used as a flame retardant.


Ortho Boric Acid is used in the manufacture of enamels and pottery glazes.
Ortho Boric Acid is used in medicines as an eye wash.
Ortho Boric Acid is used for making borosilicate glass.


Cleaning: Ortho Boric Acid is used as a natural cleaner and is commonly found in detergents.
Pesticide: Ortho Boric Acid can be used as an insecticide.
Glass and Ceramics: Ortho Boric Acid is used as a component in glass, enamel, and pottery glazes.


Metal Processing: Ortho Boric Acid is used as a flux in metal soldering.
Wood Preservation: Ortho Boric Acid is used as a preservative against wood rot.
Pharmaceutical: Ortho Boric Acid is used as an alkalizing agent in pharmaceuticals.


Chemical Laboratories: Ortho Boric Acid is used as a buffering agent.
Ortho Boric Acid and its sodium salts can be used to control a wide variety of pests. 


These include insects, spiders, mites, algae, molds, fungi, and weeds. 
Products that contain Ortho Boric Acid have been registered for use in the United States since 1948.


-Ortho Boric Acid has multiple uses in several industries, the pharmaceutical, glass, ceramic and cosmetics industries being some of them. 
Ortho Boric Acid, also known as hydrogen borate, is a chemical compound that can be produced through a series of chemical reactions. 
One common method for its production involves the reaction between borax (sodium borate) and sulfuric acid, resulting in Ortho Boric Acid as the desired product and sodium Sulphate (Na2SO4) as a byproduct.

Sodium Sulphate is a white, crystalline solid and has various industrial applications, including use in detergents, textiles, and paper production. 
Depending on the purity and market demand, the sodium Sulphate byproduct may be further processed or sold to industries that can use it.

To separate Sodium Sulphate from the liquid solution resulting from the reaction to produce Ortho Boric Acid, you can use a variety of techniques: (cooling) crystallization, evaporation, addition of precipitating agent, electrolysis, ion exchange. 

The choice of method depends on the specific requirements and constraints of the separation process. 
Factors such as energy consumption, equipment availability, the concentration of Sodium Sulphate and the desired purity of the separated Sodium Sulphate will influence the selection of the most appropriate technique.


-Agriculture uses of Ortho Boric Acid:
Ortho Boric Acid is used to treat or prevent boron deficiencies in plants. 
Ortho Boric Acid is also used in preservation of grains such as rice and wheat.


-Pharmaceutical Applications of Ortho Boric Acid:
Ortho Boric Acid is used as an antimicrobial preservative in eye drops, cosmetic products, ointments, and topical creams. 

Ortho Boric Acid is also used as an antimicrobial preservative in foods.
Ortho Boric Acid and borate have good buffering capacity and are used to control pH; they have been used for this purpose in external preparations such as eye drops.

Ortho Boric Acid has also been used therapeutically in the form of suppositories to treat yeast infections. 
In dilute concentrations Ortho Boric Acid is used as a mild antiseptic, with weak bacteriostatic and fungistatic properties, although it has generally been superseded by more effective and less toxic disinfectants.


-Ortho Boric Acid as a Medicine:
Ortho Boric Acid is widely used as an antiseptic for the treatment of minor cuts and burns. 
Furthermore, Ortho Boric Acid  is also used in medical dressings and salves. 

Very dilute solutions of Ortho Boric Acid can be used as an eyewash. 
Owing to its antibacterial properties, Ortho Boric Acid can also be used for the treatment of acne in humans. 
In its powdered form, Ortho Boric Acid can also be sprinkled into socks and shoes to prevent the athlete’s foot (tinea pedis).

It is important to note that Ortho Boric Acid can prove poisonous if consumed or inhaled in relatively large quantities. 
Furthermore, continued exposure to Ortho Boric Acid over long durations of time can severely damage the kidney.


-Medical uses of Ortho Boric Acid:
Ortho Boric Acid can be used as an antiseptic for minor burns or cuts and is sometimes used in salves and dressings, such as boracic lint. 
Ortho Boric Acid is applied in a very dilute solution as an eye wash. 

Ortho Boric Acid vaginal suppositories can be used for recurrent candidiasis due to non-albicans candida as a second line treatment when conventional treatment has failed.
Ortho Boric Acid is less effective than conventional treatment overall.

Ortho Boric Acid largely spares lactobacilli within the vagina.
Ortho Boric Acid is under development as an intravaginal medication for the treatment for vulvovaginal candidiasis.

As an antibacterial compound, Ortho Boric Acid can also be used as an acne treatment. 
Ortho Boric Acid is also used as prevention of athlete's foot, by inserting powder in the socks or stockings. 

Various preparations of Ortho Boric Acid can be used to treat some kinds of otitis externa (ear infection) in both humans and animals.
The preservative in urine sample bottles in the UK is Ortho Boric Acid.

Ortho Boric Acid solutions used as an eye wash or on abraded skin are known to be toxic, particularly to infants, especially after repeated use; this is because of its slow elimination rate.

Ortho Boric Acid is one of the most commonly used substances that can counteract the harmful effects of reactive hydrofluoric acid (HF) after an accidental contact with the skin. 

Ortho Boric Acid works by forcing the free F− anions into the inert tetrafluoroborate anion. 
This process defeats the extreme toxicity of hydrofluoric acid, particularly its ability to sequester ionic calcium from blood serum which can lead to cardiac arrest and bone decomposition; such an event can occur from just minor skin contact with HF.


-Insecticidal uses of Ortho Boric Acid:
Ortho Boric Acid was first registered in the US as an insecticide in 1948 for control of cockroaches, termites, fire ants, fleas, silverfish, and many other insects. 

Ortho Boric Acid is generally considered to be safe to use in household kitchens to control cockroaches and ants. 
Ortho Boric Acid acts as a stomach poison affecting the insects' metabolism, and the dry powder is abrasive to the insects' exoskeletons.

Ortho Boric Acid is in non-specific IRAC group 8D. 
Ortho Boric Acid also has the reputation as "the gift that keeps on killing" in that cockroaches that cross over lightly dusted areas do not die immediately, but that the effect is like shards of glass cutting them apart. 

This often allows a roach to go back to the nest where it soon dies. 
Cockroaches, being cannibalistic, eat others killed by contact or consumption of Ortho Boric Acid, consuming the powder trapped in the dead roach and killing them, too.

Ortho Boric Acid has also been widely used in the treatment of wood for protection against termites. 
The full complexity of its mechanism is not fully understood, but aside from causing dose-dependent mortality, Ortho Boric Acid causes dysbiosis in the Eastern Subterranean termite, leading to the opportunistic rise of insect pathogens that could be contributing to mortality.


-Preservation uses of Ortho Boric Acid:
In combination with its use as an insecticide, Ortho Boric Acid also prevents and destroys existing wet and dry rot in timbers. 

Ortho Boric Acid can be used in combination with an ethylene glycol carrier to treat external wood against fungal and insect attack. 
It is possible to buy borate-impregnated rods for insertion into wood via drill holes where dampness and moisture is known to collect and sit. 

Ortho Boric Acid is available in a gel form and injectable paste form for treating rot affected wood without the need to replace the timber. 
Concentrates of borate-based treatments can be used to prevent slime, mycelium, and algae growth, even in marine environments.

Ortho Boric Acid is added to salt in the curing of cattle hides, calfskins, and sheepskins. 
This helps to control bacterial development, and helps to control insects.


-pH buffer uses of Ortho Boric Acid:
Ortho Boric Acid in equilibrium with its conjugate base the borate ion is widely used (in the concentration range 50–100 ppm boron equivalents) as a primary or adjunct pH buffer system in swimming pools. 

Ortho Boric Acid is a weak acid, with pKa (the pH at which buffering is strongest because the free acid and borate ion are in equal concentrations) of 9.24 in pure water at 25 °C. 

But apparent pKa is substantially lower in swimming pool or ocean waters because of interactions with various other molecules in solution. 
It will be around 9.0 in a salt-water pool. 

No matter which form of soluble boron is added, within the acceptable range of pH and boron concentration for swimming pools, Ortho Boric Acid is the predominant form in aqueous solution, as shown in the accompanying figure. 

The Ortho Boric Acid – borate system can be useful as a primary buffer system (substituting for the bicarbonate system with pKa1 = 6.0 and pKa2 = 9.4 under typical salt-water pool conditions) in pools with salt-water chlorine generators that tend to show upward drift in pH from a working range of pH 7.5–8.2. 
Buffer capacity is greater against rising pH (towards the pKa around 9.0). 

The use of Ortho Boric Acid in this concentration range does not allow any reduction in free HOCl concentration needed for pool sanitation, but it may add marginally to the photo-protective effects of cyanuric acid and confer other benefits through anti-corrosive activity or perceived water softness, depending on overall pool solute composition


-Lubrication uses of Ortho Boric Acid:
Colloidal suspensions of nanoparticles of Ortho Boric Acid dissolved in petroleum or vegetable oil can form a remarkable lubricant on ceramic or metal surfaces[ with a coefficient of sliding friction that decreases with increasing pressure to a value ranging from 0.10 to 0.02.

Self-lubricating B(OH)3 films result from a spontaneous chemical reaction between water molecules and B2O3 coatings in a humid environment. 
In bulk-scale, an inverse relationship exists between friction coefficient and Hertzian contact pressure induced by applied load.
Ortho Boric Acid is used to lubricate carrom and novuss boards, allowing for faster play.


-Nuclear power uses of Ortho Boric Acid:
Ortho Boric Acid is used in some nuclear power plants as a neutron poison. 
The boron in Ortho Boric Acid reduces the probability of thermal fission by absorbing some thermal neutrons. 

Fission chain reactions are generally driven by the probability that free neutrons will result in fission and is determined by the material and geometric properties of the reactor. 
Natural boron consists of approximately 20% boron-10 and 80% boron-11 isotopes. 

Boron-10 has a high cross-section for absorption of low energy (thermal) neutrons. 
By increasing Ortho Boric Acid concentration in the reactor coolant, the probability that a neutron will cause fission is reduced. 
Changes in Ortho Boric Acid concentration can effectively regulate the rate of fission taking place in the reactor. 

During normal at power operation, Ortho Boric Acid is used only in pressurized water reactors (PWRs), whereas boiling water reactors (BWRs) employ control rod pattern and coolant flow for power control, although BWRs can use an aqueous solution of Ortho Boric Acid and borax or sodium pentaborate for an emergency shutdown system if the control rods fail to insert. 

Ortho Boric Acid may be dissolved in spent fuel pools used to store spent fuel elements. 
The concentration is high enough to keep neutron multiplication at a minimum. 
Ortho Boric Acid was dumped over Reactor 4 of the Chernobyl nuclear power plant after its meltdown to prevent another reaction from occurring.


-Pyrotechnics uses of Ortho Boric Acid:
Boron is used in pyrotechnics to prevent the amide-forming reaction between aluminium and nitrates.
A small amount of Ortho Boric Acid is added to the composition to neutralize alkaline amides that can react with the aluminium.

Ortho Boric Acid can be used as a colorant to make fire green. 
For example, when dissolved in methanol Ortho Boric Acid is popularly used by fire jugglers and fire spinners to create a deep green flame much stronger than copper sulfate.

MODE OF ACTION OF ORTHO BORIC ACID:
The mode of action of Ortho Boric Acid and what makes it so effective in the pest control industry is its ability to kill insects without the use of highly toxic chemicals. 

When applied, Ortho Boric Acid acts as a stomach poison to the insects which come into contact with the Ortho Boric Acid or consume it. 
Ortho Boric Acid is very abrasive and can cut through the outer shell of numerous insects.

For instance, if roaches were to pass over an area treated with Ortho Boric Acid, the slow killing chemical behaves like shards of glass cutting them apart. 
The slow-killing effect gives roaches a chance to return to the nest where Ortho Boric Acid soon dies. 

Other cockroaches will then eat the dead carcass of a roach who consumed Ortho Boric Acid, which eventually kills them too.
The cycle continues until the Ortho Boric Acid has more-or-less been exhausted or the queen herself has consumed some, killing her, which destroys the colony.

BENEFITS OF ORTHO BORIC ACID:
What gives Ortho Boric Acid an advantage over other pesticide options is its residual effect. 
Ortho Boric Acid can still continue to kill long after it has been applied, up to a year. 
Ortho Boric Acid also has no repellent properties so target pests won’t know to stay away from treated areas.

While Ortho Boric Acid alone will not be potent enough to address heavy infestations (aside from fleas living in the carpet), it can be very effective when applied in cracks and crevices or between walls to keep insects from residing and surviving in those areas.

Ortho Boric Acid can also be scattered outside structures in lawn and fields in the form of a granular bait. 
Ortho Boric Acid is a key ingredient not only in pest control products but also can be used as an antiseptic to address medical problems, a preservative for skins, a lubricant and even for pyrotechnics.

PREPARATION OF ORTHO BORIC ACID:
Ortho Boric Acid is produced from borax, colemanite, or other inorganic borates by reaction with sulfuric acid or hydrochloric acid, and cooling the solution to proper temperature:
Na2B4O7 ? 10Η2Ο + H2SO4 → 4H3BO3 + Na2SO4 + 5H2O

Ortho Boric Acid also may be prepared by extraction of weak borax brine with a kerosene solution of an aromatic diol, such as 2-ethyl-1,3-hexanediol or 3-chloro- 2-hydroxy-5-(1,1,3,3-tetramethylbutyl)benzyl alcohol. 

The diol-borate chelate formed separates into a kerosene phase. Treatment with sulfuric acid yields Ortho Boric Acid which partitions into aqueous phase and is purified by recrystallization.

PRODUCTION METHODS OF ORTHO BORIC ACID:
Ortho Boric Acid occurs naturally as the mineral sassolite. 
However, the majority of Ortho Boric Acid is produced by reacting inorganic borates with sulfuric acid in an aqueous medium. 

Sodium borate and partially refined calcium borate (colemanite) are the principal raw materials. 
When Ortho Boric Acid is made from colemanite, the fineground ore is vigorously stirred with mother liquor and sulfuric acid at about 908℃. 
The by-product calcium sulfate is removed by filtration, and the Ortho Boric Acid is crystallized by cooling the filtrate.

CHEMICAL PROPERTIES OF ORTHO BORIC ACID:
Ortho Boric Acid is a white powder or granules and odorless. 
Ortho Boric Acid is incompatible with potassium, acetic anhydride, alkalis, carbonates, and hydroxides. 

Ortho Boric Acid has uses in the production of textile fiberglass, flat panel displays, and eye drops. 
Ortho Boric Acid is recognized for its application as a pH buffer and as a moderate antiseptic agent and emulsifier.

Ortho Boric Acid is a white, amorphous powder or colorless, crystalline solid.
Ortho Boric Acid occurs as a hygroscopic, white crystalline powder, colorless shiny plates, or white crystals.

PHYSICAL PROPERTIES OF ORTHO BORIC ACID:
Ortho Boric Acid is a colorless, transparent triclinic crystal or white granule or powder; 
density 1.435 g/cm3; 
melts at 171°C under normal heating; 
however, slow heating causes loss of water; 
sparingly soluble in cold water (4.7% at 20°C); 
pH of 0.1M solution 5.1; 
readily dissolves in hot water (19.1% at 80°C and 27.5% at 100°C); 
also soluble in lower alcohols and moderately soluble in pyridine.

PROPETIES OF ORTHO BORIC ACID:
Ortho Boric Acid is a white crystalline solid usually found in powder form.
Ortho Boric Acid has a feeling of soft soapy touch.

Ortho Boric Acid is sparingly soluble in cold water but highly soluble in hot water.
Ortho Boric Acid tends to behave as a very weak acid.
Ortho Boric Acid dehydrates when heated above 170 °C and goes on to form metaboric acid.

STRUCTURE OF ORTHO BORIC ACID:
Ortho Boric Acid has a trigonal structure. 
If we look at the chemical formula of Ortho Boric Acid, it is BH3O3. Here, the three oxygen atoms form a trigonal planar geometry around the boron. 

The B-O bond length is 136 pm, and the O-H is 97 pm. 
The molecular point group is C3h.

Crystalline boric acid is made up of layers of B(OH)3 molecules that are held together by hydrogen bonds of length 272 pm. 
The distance between two adjacent layers is 318 pm.

HISTORY OF ORTHO BORIC ACID:
Ortho Boric Acid was first prepared by Wilhelm Homberg (1652–1715) from borax, by the action of mineral acids, and was given the name sal sedativum Hombergi ("sedative salt of Homberg"). 
However Ortho Boric Acid and borates have been used since the time of the ancient Greeks for cleaning, preserving food, and other activities.

Molecular and crystal structure
The three oxygen atoms form a trigonal planar geometry around the boron. 

The B-O bond length is 136 pm and the O-H is 97 pm. 
The molecular point group is C3h.

Two crystalline forms of Ortho Boric Acid are known: triclinic with space group P1, and trigonal with space group P32. 
The former is the most common; the second, which is a bit more stable thermodynamically, can be obtained with a special preparation method.

The triclinic form of Ortho Boric Acid consists of layers of B(OH)3 molecules held together by hydrogen bonds with an O...O separation of 272 pm. 
The distance between two adjacent layers is 318 pm.

While the layers of the triclinic phase are nearly trigonal with γ = 119.76°, a = 701.87 pm, and b = 703.5 pm (compared to a = 704.53(4) pm for the trigonal form), the stacking of the layers is somewhat offset in the triclinic phase, with α = 92.49° and β = 101.46°. 
The triclinic phase has c = 634.72 pm and the trigonal one has a = 956.08(7) pm

PREPARATION OF ORTHO BORIC ACID:
There are two common methods for the preparation of Ortho Boric Acid.

*Using borax: 
Ortho Boric Acid can be obtained by treating a hot concentrated solution of borax with either sulphuric acid or hydrochloric acid. 

As a result of the solution on concentration, crystals of Ortho Boric Acid are formed.
Na2B4O7•10H2O + 2 HCl → 4 B(OH)3 [or H3BO3] + 2 NaCl + 5 H2O


*Hydrolysis of boron compounds: 
Another method that can be used is hydrolysis. 

Ortho Boric Acid can be performed on boron compounds such as hydrides, halides and nitrides.
B2H6 + 6 H2O → 2 B(OH)3 + 6 H2
BX3 + 3 H2O → B(OH)3 + 3 HX (X = Cl, Br, I)

BIOCHEM/PHYSIOL ACTIONS OF ORTHO BORIC ACID:
Ortho Boric Acid has antibacterial and fungicidal properties. 
Ortho Boric Acid is used in the periodontal therapy as an irrigation solution as it elicits bactericidal effects in microbial biofilms in root canal. 

Ortho Boric Acid may favor osteoblastic activity and inhibit bone loss. 
Ortho Boric Acid inhibits Candida albicans fungal infection and has potential to treat vaginal infection.

PURIFICATION METHODS OF ORTHO BORIC ACID:
Crystallise the acid three times from H2O (3mL/g) between 100o and 0o, after filtering through sintered glass.
Dry it to constant weight over metaOrtho Boric Acid in a desiccator. 

Ortho Boric Acid is steam volatile. 
After two recrystallisations of ACS grade. it had Ag at 0.2 ppm.

Ortho Boric Acid's solubility (%) in H2O is 2.66 at 0o, 4.0 at 12o and 24 at 80o. 
At 100o it loses H2O to form metaOrtho Boric Acid (HBO2). 

When it is heated to redness or slowly to 200o, or over P2O5 in vacuo, it dehydrates to boric anhydride (B2O3) [1303-82-6] to give a white hard glass or crystals with m ~294o.

The glass softens on heating and liquefies at red heat. 
Ortho Boric Acid is an astringent, a fungicide and an antibacterial. 

PREPARATION OF ORTHO BORIC ACID:
One of the simplest methods of preparing Ortho Boric Acid is by reacting borax with any mineral acid (hydrochloric acid, for instance). 
The chemical equation for this reaction can be written as:

Na2B4O7.10H2O + 2HCl → 4H3BO3 + 5H2O + 2NaCl
Ortho Boric Acid can also be prepared from the hydrolysis of diborane and trihalides of boron (such as boron trichloride or boron trifluoride).

PROPERTIES OF ORTHO BORIC ACID:
Under standard conditions for temperature and pressure (STP), Ortho Boric Acid exists as a white, crystalline solid that is fairly soluble in water. 
The solubility of Ortho Boric Acid in water is temperature-dependent. 
At a temperature of 25 °C, the solubility of Ortho Boric Acid in water is 57 g/L. 

However, when the water is heated to 100 °C, the solubility of Ortho Boric Acid increases to approximately 275 g/L. 
It can also be noted that Ortho Boric Acid is sparingly soluble in pyridine and slightly soluble in acetone. 
The conjugate base of Ortho Boric Acid is the borate anion. 

The acidity of solutions of Ortho Boric Acid is known to increase with polyols containing cis-vicinal diols (like mannitol and glycerol). 
The value of pK of B(OH)3 is known to extend to five orders of magnitude (from 9 to 4), under different concentrations of mannitol. 
It can be noted that in the presence of mannitol, the solution of Ortho Boric Acid with increased acidity can be referred to as mannitoOrtho Boric Acid.

STRUCTURE OF ORTHO BORIC ACID:
Each Ortho Boric Acid molecule features boron-oxygen single bonds. 
The boron atom occupies the central position and is linked to three hydroxide groups. 

The overall molecular geometry of Ortho Boric Acid is trigonal planar. 
The structure of Ortho Boric Acid molecules is illustrated below. 

ORTHO BORIC ACID FOULING:
Crystallization, is one of the most common methods for separating salts like Sodium Sulphate from a liquid solution. 
The solution is heated to evaporate the water, leaving behind solid Sodium Sulphate crystals. 

The crystals can then be separated from the remaining liquid by filtration. 
This process can be repeated if higher purity sodium Sulphate is required.

Fouling is a common issue in industrial separation processes using evaporators or crystallizers, including the separation of Sodium Sulphate from liquid solutions. 

Fouling refers to the accumulation of unwanted deposits or impurities on the surfaces of equipment and can lead to reduced process efficiency, increased maintenance and energy consumption, and even equipment damage. 

When separating Sodium Sulphate from a liquid solution, fouling issues can arise due to various factors, such as scaling1, Impurities2, and chemical reactions3.

Regular cleaning and use of chemicals (scale inhibitors) are common approaches to improve operations, but they often do not yield the desired results. 

1 One of the primary fouling issues in sodium Sulphate separation is the formation of scale. 
As the solution is concentrated or cooled to crystallize sodium Sulphate, the salt may precipitate and adhere to the surfaces of equipment, such as heat exchangers, pipes, and crystallization vessels.

2 The presence of impurities in the liquid solution can contribute to fouling. 
These impurities may include other salts, organic compounds, or particulate matter, which can deposit on equipment surfaces during the separation process.

3 Chemical reactions between components in the solution and the equipment surfaces can result in fouling. 
For example, if the equipment is not made from materials that are resistant to the chemicals in the solution, corrosion and fouling can occur.

WHAT IS THE STRUCTURE OF ORTHO BORIC ACID?
Ortho Boric Acid contains triangular BO33- units. 
In the solid, the B(OH)3 units are hydrogen bonded together into two−dimensional sheets with almost hexagonal symmetry. 
The layers are quite a large distance apart and thus the crystal breaks quite easily into very fine particles

PREPARATION OF ORTHO BORIC ACID:
Ortho Boric Acid may be prepared by reacting borax (sodium tetraborate decahydrate) with a mineral acid, such as hydrochloric acid:
Na2B4O7•10H2O + 2 HCl → 4 B(OH)3 + 2 NaCl + 5 H2O
Ortho Boric Acid is also formed as a by product of hydrolysis of boron trihalides and diborane:

B2H6 + 6 H2O → 2 B(OH)3 + 6 H2
BX3 + 3 H2O → B(OH)3 + 3 HX (X = Cl, Br, I)

REACTIONS OF ORTHO BORIC ACID:
Pyrolysis
When heated, Ortho Boric Acid undergoes a three step dehydration. The reported transition temperatures vary substantially from source to source.
When heated above 140 °C, Ortho Boric Acid yields metaboric acid (HBO2) with loss of one water molecule:

B(OH)3 → HBO2 + H2O
Heating metaboric acid above about 180 °C eliminates another water molecule forming tetraboric acid, also called pyroboric acid (H2B4O7):

4 HBO2 → H2B4O7 + H2O
Further heating (to about 530 °C) leads to boron trioxide:
H2B4O7 → 2 B2O3 + H2O


Aqueous solution
When Ortho Boric Acid is dissolved in water, it partially dissociates to give metaboric acid:
B(OH)3 ⇌ HBO2 + H2O
The solution is mildly acidic due to ionization of the acids:

B(OH)3 + H2O ⇌ [BO(OH)2]− + H3O+
HBO2 + H2O ⇌ [BO2]− + H3O+
However, Raman spectroscopy of strongly alkaline solutions has shown the presence of [B(OH)4]− ions, leading some to conclude that the acidity is exclusively due to the abstraction of OH− from water:

B(OH)3 + HO− ⇌ B(OH)−4
Equivalently,

B(OH)3 + H2O ⇌ B(OH)−4 +  H+ (Ka = 7.3×10−10; pKa = 9.14)
Or, more properly,

B(OH)3 + 2 H2O ⇌ B(OH)−4 + H3O+
This reaction occurs in two steps, with the neutral complex aquatrihydroxyboron B(OH)3(OH2) as an intermediate:

B(OH)3 + H2O → B(OH)3(OH2)
B(OH)3(OH2) + H2O → [B(OH)4]− + H3O+

This reaction may be characterized as Lewis acidity of boron toward HO−, rather than as Brønsted acidity.
However, some of its behaviour towards some chemical reactions suggest it to be a tribasic acid in the Brønsted-Lowry sense as well.

Boric acid, mixed with borax Na2B4O7•10H2O (more properly Na2B4O5(OH)4•8H2O) in the weight ratio of 4:5, is highly soluble in water, though they are not so soluble separately


Sulfuric acid solution
Boric acid also dissolves in anhydrous sulfuric acid according to the equation:

B(OH)3 + 6 H2SO4 → [B(SO4H)4]− + 2 [HSO4]− + 3 H3O+
The product is an extremely strong acid, even stronger than the original sulfuric acid.


Esterification
Boric acid reacts with alcohols to form borate esters, B(OR)3 where R is alkyl or aryl. 
The reaction is typically driven by a dehydrating agent, such as concentrated sulfuric acid:
B(OH)3 + 3 ROH → B(OR)3 + 3 H2O


With vicinal diols
The acidity of boric acid solutions is greatly increased in the presence of cis-vicinal diols (organic compounds containing similarly oriented hydroxyl groups in adjacent carbon atoms, (R1,R2)=C(OH)−C(OH)=(R3,R4)) such as glycerol and mannitol.


The tetrahydroxyborate anion formed in the dissolution spontaneously reacts with these diols to form relatively stable anion esters containing one or two five-member −B−O−C−C−O− rings. 
For example, the reaction with mannitol H(HCOH)6H, whose two middle hydroxyls are in cis orientation, can be written as

B(OH)3 + H2O ⇌ [B(OH)4]− + H+[B(OH)4]− + H(HCOH)6H ⇌ [B(OH)2(H(HCOH)2(HCO−)2(HCOH)2H)]− + 2 H2O
[B(OH)2(H(HCOH)2(HCO−)2(HCOH)2H)]− + H(HCOH)6H ⇌ [B(H(HCOH)2(HCO−)2(HCOH)2H)2]− + 2 H2O


Giving the overall reaction
B(OH)3 + 2 H(HCOH)6H ⇌ [B(H(HCOH)2(HCO−)2(HCOH)2H)2]− + 3 H2O + H+

The stability of these mannitoborate ester anions shifts the equilibrium of the right and thus increases the acidity of the solution by 5 orders of magnitude compared to that of pure boric oxide, lowering the pKa from 9 to below 4 for sufficient concentration of mannitol.

The resulting solution has been called mannitoboric acid.
The addition of mannitol to an initially neutral solution containing boric acid or simple borates lowers its pH enough for it to be titrated by a strong base as NaOH, including with an automated a potentiometric titrator. 

This property is used in analytical chemistry to determine the borate content of aqueous solutions, for example to monitor the depletion of boric acid by neutrons in the water of the primary circuit of light-water reactor when the compound is added as a neutron poison during refueling operations.

PREPARATION METHODS OF ORTHO BORIC ACID:
Ortho Boric Acid can be prepared by acidifyng an aqueous solution of borax.

Ortho Boric Acid is also formed by the hydrolysis (reaction with water or dilute acid) of boron compounds (halides, hydrides, etc.).
BX3 + 3 H2O → B(OH)3 + 3 HX (X = Cl, Br, I)
B2H6 + 6 H2O → 2 B(OH)3 + 6 H2

PROPERTIES OF ORTHO BORIC ACID:
Ortho Boric Acid has a layer structure in which planar BO3 units are joined by hydrogen bonds.
Ortho Boric Acid is a weak monobasic acid. It is not a protonic acid but acts as a Lewis acid by accepting electrons from a hydroxyl ion.
On heating, Ortho Boric Acid above 370K forms meta Ortho Boric Acid, HBO2 which on further heating yields boric oxide, B2O3

WHAT ARE SOME PRODUCTS THAT CONTAIN ORTHO BORIC ACID?
What are some products that contain Ortho Boric Acid?
Products containing Ortho Boric Acid can be liquids, granules, pellets, tablets, wettable powders, dusts, rods, or baits. 

They are used indoors in places like homes, hospitals and commercial buildings. 
They are also used in outdoor residential areas, sewage systems, and on food and non-food crops. 

There are over five hundred products with Ortho Boric Acid sold in the United States. 
Several non-pesticide products containing Ortho Boric Acid include soil amendments, fertilizers, household cleaners, laundry detergents, and personal care products.

HOW DOES ORTHO BORIC ACID WORK?
Ortho Boric Acid can kill insects if they eat it. 
Ortho Boric Acid disrupts their stomach and can affect their nervous system. 

Ortho Boric Acid can also scratch and damage the exterior of insects. 
Ortho Boric Acid and borax, a sodium borate salt, can kill plants by causing them to dry out. 

Sodium metaborate, another sodium borate salt, stops plants from producing the energy they need from light. 
Ortho Boric Acid can also stop the growth of fungi, such as mold. 
Ortho Boric Acid prevents them from reproducing.

PHYSICAL and CHEMICAL PROPERTIES of ORTHO BORIC ACID:
Chemical formula: BH3O3
Molar mass: 61.83 g/mol
Appearance: White crystalline solid
Density: 1.435 g/cm³
Melting point: 170.9 °C (339.6 °F; 444.0 K)
Boiling point: 300 °C (572 °F; 573 K)
Solubility in water:
2.52 g/100 mL (0 °C)
4.72 g/100 mL (20 °C)
5.7 g/100 mL (25 °C)
19.10 g/100 mL (80 °C)
27.53 g/100 mL (100 °C)

Solubility in other solvents:
Soluble in lower alcohols
Moderately soluble in pyridine
Very slightly soluble in acetone
log P: -0.29
Acidity (pKa): 9.24 (first proton), 12.4 (second), 13.3 (complete)
Conjugate base: Borate
Magnetic susceptibility (χ): -34.1·10^(-6) cm³/mol
Molecular Weight: 61.84 g/mol
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0

Exact Mass: 62.0175241 g/mol
Monoisotopic Mass: 62.0175241 g/mol
Topological Polar Surface Area: 60.7 Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular Weight/ Molar Mass: 61.83 g/mol
Density: 1.435 g/cm³ (standard)
1.48 g/cm³ (at 23 °C)
Boiling Point: 158 °C
Melting Point:
300 °C (standard)
1000 °C (decomposition)
CAS Number: 10043-35-3

EC Index Number: 005-007-00-2
EC Number: 233-139-2
Hill Formula: BH₃O₃
Chemical Formula: H₃BO₃
HS Code: 2810 00 90
Quality Level: MQ200
Additional Properties:
pH Value: 5.1 (1.8 g/l, H₂O, 25 °C)
Vapor Pressure: <0.1 hPa (25 °C)
Bulk Density: 400 - 600 kg/m³

Solubility: 49.2 g/l
Physical Properties:
Physical State: Crystalline
Color: White
Odor: Odorless
Melting Point/Freezing Point: 160 °C
Initial Boiling Point and Boiling Range: No data available
Flammability (Solid, Gas): Not flammable (solid)
Upper/Lower Flammability or Explosive Limits: 
No data available

Flash Point: Not applicable
Autoignition Temperature: No data available
Decomposition Temperature: No data available
Chemical Properties:
pH: 5.1 at 1.8 g/l at 25 °C
Solubility:
Water Solubility: 49.2 g/l at 20 °C, completely soluble
Partition Coefficient (n-Octanol/Water):
log Pow: -1.09 at 22 °C
Vapor Pressure: < 0.1 hPa at 25 °C
Density: 1.48 g/cm³ at 23 °C

Relative Density: 1.49 at 23 °C
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: None
Safety Information:
Dissociation Constant: 8.94 at 20 °C
Chemical Properties (Recap):
IUPAC Names: Boric acid, Trihydroxidoboron
Chemical Formula: BH₃O₃
Molar Mass: 61.83 g/mol

Appearance: White crystalline solid
Density: 1.435 g/cm³
Melting Point: 170.9 °C
Boiling Point: 300 °C
Solubility in Water:
2.52 g/100 mL at 0 °C
4.72 g/100 mL at 20 °C
5.7 g/100 mL at 25 °C
19.10 g/100 mL at 80 °C
27.53 g/100 mL at 100 °C

Solubility in Other Solvents:
Soluble in lower alcohols
Moderately soluble in pyridine
CBNumber:CB6128144
Molecular Formula:BH3O3 Lewis structure
Molecular Weight:61.83
MDL Number:MFCD00236358
MOL File:10043-35-3.mol
Solubility: Slightly soluble in acetone and pyridine.
Molecular Shape: Trigonal planar

Dipole Moment: Zero
Appearance: White granular
Color: White
Melting Point: Approximately 185°C (decomposition)
Density: 1.435 g/cm³
Odor: Odorless
Flash Point: None
Assay Percent Range: 99.8%
Physical Form: Granular

Beilstein Number: 1697939
Formula Weight: 61.83 g/mol
Chemical Name or Material: Boric acid
Melting point: 160 °C (dec.) (lit.)
Boiling point: 219-220 °C (9.7513 mmHg)
Density: 1.440 g/cm³
Vapor pressure: 2.6 mm Hg (20 °C)
Storage temperature: Store at +5°C to +30°C.
Solubility: H2O: soluble
Form: working solution
pKa: 8.91±0.43 (Predicted)

Specific Gravity: 1.435
Color: ≤10 (APHA)
pH: 3.6-4.4 (25℃, saturated solution in H2O)
Odor: Odorless
pH Range: 3.8 - 4.8
Water Solubility: 49.5 g/L (20 ºC)
Sensitivity: Hygroscopic
λmax (Maximum Absorption Wavelength): λ: 260 nm Amax: 0.05, 
λ: 280 nm Amax: 0.05
Merck Index: 14,1336

BRN (Beilstein Registry Number): 1697939
Exposure limits: ACGIH: TWA 2 mg/m3; STEL 6 mg/m3
InChIKey: KGBXLFKZBHKPEV-UHFFFAOYSA-N
LogP: -1.09 at 22℃
Substances Added to Food (formerly EAFUS): BORIC ACID
CAS DataBase Reference: 10043-35-3(CAS DataBase Reference)
FDA UNII: R57ZHV85D4
NIST Chemistry Reference: B(OH)3(10043-35-3)
EPA Substance Registry System: Orthoboric acid (10043-35-3)

IUPAC names: Boric acid, Trihydroxidoboron
Chemical formula: BH3O3
Molar mass: 61.83 g·mol−1
Appearance: White crystalline solid
Density: 1.435 g/cm3
Melting point: 170.9 °C (339.6 °F; 444.0 K)
Boiling point: 300 °C (572 °F; 573 K)
Solubility in water: 2.52 g/100 mL (0 °C), 
4.72 g/100 mL (20 °C), 
5.7 g/100 mL (25 °C), 
19.10 g/100 mL (80 °C), 27.53 g/100 mL (100 °C)

Solubility in other solvents: Soluble in lower alcohols, 
Moderately soluble in pyridine, 
Slightly soluble in acetone
Molecular shape: Trigonal planar
Dipole moment: Zero
CBNumber: CB6128144
Molecular Formula: BH3O3
Molecular Weight: 61.83
MDL Number: MFCD00236358
MOL File: 10043-35-3.mol
Melting point: 160 °C (dec.) (lit.)
Boiling point: 219-220 °C (9.7513 mmHg)

Density: 1.440 g/cm3
Bulk density: 400-600kg/m3
Vapor pressure: 2.6 mm Hg (20 °C)
Refractive index: n20/D 1.330-1.340
Storage temp.: Store at +5°C to +30°C
Solubility: H2O: soluble
Form: Working solution
pKa: 8.91±0.43 (Predicted)
Specific Gravity: 1.435
Color: ≤10 (APHA)
pH: 3.6-4.4 (25°C, saturated solution in H2O)

Odor: Odorless
pH Range: 3.8 - 4.8
Water Solubility: 49.5 g/L (20 ºC)
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.05, λ: 280 nm Amax: 0.05
Merck: 14,1336
BRN: 1697939
Exposure limits: ACGIH: TWA 2 mg/m3; STEL 6 mg/m3
InChIKey: KGBXLFKZBHKPEV-UHFFFAOYSA-N
LogP: -1.09 at 22°C
Substances Added to Food (formerly EAFUS): BORIC ACID

CAS DataBase Reference: 10043-35-3 (CAS DataBase Reference)
FDA UNII: R57ZHV85D4
NIST Chemistry Reference: B(OH)3 (10043-35-3)
EPA Substance Registry System: Orthoboric acid (10043-35-3)
Absorption: ≤0.05 at 260 in H2O at 1M, ≤0.05 at 280 in H2O at 1M
UNSPSC Code: 41116116
NACRES: NB.21
Physical state: Crystalline
Color: White
Odor: Odorless
Melting point/freezing point: Melting point/range: 160 °C - dec.

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 5.1 at 1.8 g/l at 25°C
Viscosity: 
Viscosity, kinematic: No data available, 
Viscosity, dynamic: No data available
Water solubility: 49.2 g/l at 20 °C, completely soluble
Partition coefficient: n-octanol/water, log Pow: -1.09 at 22 °C

Vapor pressure: < 0.1 hPa at 25 °C
Density: 1.48 g/cm3 at 23 °C
Relative density: 1.49 at 23 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: None
Other safety information: Dissociation constant 8.94 at 20 °C
Chemical Formula: H₃BO₃
Molecular Weight: 61.83 g/mol
CAS Number: 10043-35-3
Appearance: White crystalline powder
Solubility: Soluble in water

FIRST AID MEASURES of ORTHO BORIC ACID:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air. 
Call in physician.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with water/ shower. 
Consult a physician.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of ORTHO BORIC ACID:
-Environmental precautions:
Do not let product enter drains
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills. 
Take up carefully. 
Dispose of properly. 

FIRE FIGHTING MEASURES of ORTHO BORIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of ORTHO BORIC ACID:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ORTHO BORIC ACID:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing. 
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry. 
Keep in a well-ventilated place. 
Keep locked up or in an area accessible only to qualified or authorized persons.
Recommended storage temperature see product label.
*Storage class:
Storage class (TRGS 510): 6.1D: 
Non-combustible.

STABILITY and REACTIVITY of ORTHO BORIC ACID:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available


 

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