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In industry, PEG-20 Sorbitan Monooleate (Polysorbate 80) is used mainly due to its emulsifying properties.
In addition, PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as a wetting agent or formulation stabilizer.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as emulsifiers and dispersing agents in medicinal products, defoamers and emulsifiers in foods, and surfactants for pharmaceuticals.
CAS Number: 9005-65-6
EC Number： 500-019-9
Chemical formula: C64H124O26
E number: E433 (thickeners, ...)
SYNONYMS:
Coco glucosides, CG, alkyl polyglycosides, alkyl C12-C14 polyglycosides, coconut glycosides, coco glucoside, palm kernel/Coco Glucoside
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UNII-2MSF640LWM, UNII-58O7V09UCI, UNII-6OZP39ZG8H, VALUE TN 80, WITCONOL 2722, polyoxyethylene-sorbitan-20 mono-oleate, sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs, (Z)-, Montanox 80, Alkest TW 80, Tween 80, PS 80, E433, Polyoxyethylene Sorbitan Monooleate, Polyoxyethylene (20) Sorbitan Monooleate, Polyethylene Oxide Sorbitan Mono-Oleate Polysorbate 80, alkamuls PSML-80/100, crodalan AWS, emasol O-120V, glycosperse O-20, glycosperse O-20 KFG, 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl (E)-octadec-9-enoate, kaopan TW-O-120, liposorb O-20, lonzest SMO-20, monebatt - 80, mulsifan SMO-20, nikkol TO-10MV, nikkol TO-10V, norfox sorbo T-80, poe-20 sorbitan monooleate, polyoxyethylene (20) sorbitan monooleate, polysorbate 81, rheodol TW-O120V, toximul see-341, tween 80
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a surfactant which can also reduce bacterial attachment and inhibit biofilm formation.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is an amber-colored viscous liquid.
pH (5% aqueous solution) of PEG-20 Sorbitan Monooleate (Polysorbate 80) is 5-7.
PEG-20 Sorbitan Monooleate (Polysorbate 80) has faint odor and bitter taste.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is an ingredient commonly used in cosmetics as an emulsifier and surfactant.
PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as a bridge between water and oil-based ingredients, allowing them to mix and form stable emulsions.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is derived from natural sources and is commonly produced by the esterification of sorbitol with fatty acids derived from vegetable oils.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s chemical formula is C64H124O26.
PEG-20 Sorbitan Monooleate (Polysorbate 80) appears as a yellowish, viscous liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is an amber/golden-colored water-soluble viscous liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is manufactured from polyethoxylated sorbitan (derived from the dehydration of sorbitol, a sugar alcohol) and oleic acid, a fatty acid found in animal and vegetable fats.
Due to this structure, PEG-20 Sorbitan Monooleate (Polysorbate 80) forms an approximate hydrophilic-lipophilic balance of 15.
The final products are free from genetically modified organisms and of vegetable origin.
The solubility of PEG-20 Sorbitan Monooleate (Polysorbate 80) allows it to assist in dissolving ingredients that would remain solid under normal circumstances.
In foods like ice cream, PEG-20 Sorbitan Monooleate (Polysorbate 80) is added up to 0.5% (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting.
Vitamins, tablets, and supplements also contain PEG-20 Sorbitan Monooleate (Polysorbate 80) because of its preservative nature.
In order to get the same wonderful colors you use in your other bath and body products, add PEG-20 Sorbitan Monooleate (Polysorbate 80) at about 2 % (of your total batch) in your liquid stage.
This should eliminate any ring around the tub or floating mica that can occur if you don't use PEG-20 Sorbitan Monooleate (Polysorbate 80).
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a lemon to amber colored liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a yellow liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is the chemical name for a chemical known in the INCI nomenclature as Polysorbate 80.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s CAS number is 9005-65-6.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is produced by the ethoxylation of a molecule called sorbitan.
Sorbitan is the dehydrated form of sorbitol, a sugar alcohol naturally found in some fruits.
Ethoxylation is a chemical reaction that adds ethylene oxide to a substrate, in this case sorbitan.
Sorbitan reacts with 80 ethylene oxide units, which hence “80” in the ingredient’s name.
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be of plant or animal origin.
Fatty acids directly involved in PEG-20 Sorbitan Monooleate (Polysorbate 80)'s production are obtained, for example, from olive oil or are derived from animal products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as an emulsifier for pesticide formulations, mainly for EC, SL, EW, ME, WP, WG formulations.
The textile industry uses PEG-20 Sorbitan Monooleate (Polysorbate 80) to soften the fibers and improve the efficiency and productivity of the dyeing process.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as emulsifier, stabiliser in a large range of foods including chewing gum, ice cream, soft drinks.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used in a wide range of detergents, pharmaceuticals and beauty and skin products.
Textiles: PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a wetting agent and lubricant.
PEG-20 Sorbitan Monooleate (Polysorbate 80), also known as PEG 80 and Polyoxyethylene Sorbitan Monooleate, is a polyoxyethylene derivative of sorbitan and olive oil in the form of oleic acid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also regarded as a detergent.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a emulsifier with lower surface-active agent and with lowers surface tension between non mixable liquids.
The lower surface tension allows the two liquids to share a larger contact surface.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a surfactant and emulsifier molecule.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used in food (E433), cosmetics and medicines.
Atoms are represented as spheres with conventional color coding: hydrogen (white), carbon (grey), oxygen (red).
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a hydrophilic and lipophilic nonionic surfactant made by ethoxylating sorbitan and oleic acid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is an amber-colored viscous liquid with a hydrophilic-lipophilic balance value of 15.
In addition, PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in water, methanol, and ethanol, and insoluble in mineral oil.
PEG-20 Sorbitan Monooleate (Polysorbate 80) (polyoxyethylene sorbitan monooleate) is derived from olive oil.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a non-toxic, nonionic surfactant/emulsifier and a water-soluble yellowish liquid used as a dispersing agent which allows oil and water to mix without the use of alcohol.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s a fragrance solubilizer and stabilizer; it lubricates and has a soothing effect on the skin.
This skin- safe ingredient, PEG-20 Sorbitan Monooleate (Polysorbate 80), is used extensively in oil-in-water emulsions (lotions, conditioners, cream rinses, shampoos, liquid soaps, body polishes or scrubs, etc.) and also for body mists and linen sprays.
PEG-20 Sorbitan Monooleate (Polysorbate 80) will be found as an ingredient in many body toiletries, cosmetics and wipes now in the market.
PEG-20 Sorbitan Monooleate (Polysorbate 80) also known as Tween 80.It is an amber/golden-colored viscous liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is made from polyethoxylated sorbitan (chemical compounds derived from the dehydration of sugar alcohol) and oleic acid, a fatty acid found in animal and vegetable fats.
Though PEG-20 Sorbitan Monooleate (Polysorbate 80)’s considered safe, some are convinced it has potentially dangerous health effects.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a colorless to yellow liquid used as an emulsifier in foods.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a nonionic surfactant and emulsifier often used in foods and cosmetics.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a viscous, water-soluble yellow liquid. Polysorbate 80 is used to enable medications to pass through the blood brain barrier.
There some that question PEG-20 Sorbitan Monooleate (Polysorbate 80)'s use as a food additive as when it is consumed in food it may allow toxic chemicals in the body to pass through the blood brain barrier.
PEG-20 Sorbitan Monooleate (Polysorbate 80) and designated as E 433 in the European Union, is a non-ionic surfactant and emulsifier derived from sorbitol, ethylene oxide, and oleic acid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a viscous, water-soluble yellow liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s amphiphilic structure, containing both hydrophilic (water-loving) and lipophilic (fat-loving) parts, allows it to reduce surface tension between immiscible substances like oil and water, facilitating the formation of stable emulsions.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a versatile compound widely used in the food and pharmaceutical industries.
PEG-20 Sorbitan Monooleate (Polysorbate 80) belongs to the family of polysorbate surfactants.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is derived from sorbitol, a sugar alcohol, and oleic acid, a fatty acid obtained from natural sources like olive oil.
The resulting compound PEG-20 Sorbitan Monooleate (Polysorbate 80), also known as Tween 80, exhibits exceptional emulsifying properties due to its unique chemical structure.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is extracted by chemical processes from the sweet-smelling fruits like apples, pears, peaches, and prunes, this surfactant is used in cosmetics, personal care, pharmaceutical, food, drug, textile, and metalworking industries.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is composed of a hydrophilic (water-attracting) polyoxyethylene chain and a lipophilic (fat-attracting) sorbitan ester chain.
The lipophilic section, derived from sorbitan and oleic acid, anchors the compound within fat-based substances.
This dual nature enables PEG-20 Sorbitan Monooleate (Polysorbate 80) to form micelles. These micelles are small structures in which the hydrophobic tails cluster together while the hydrophilic heads extend outward.
This produces a stable emulsion.
This property is particularly useful in the manufacture of smooth and consistent textures in items like ice cream, salad dressings, and baked goods.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is assigned the European food additive number E433.
The E numbers, or E additives, are codes for substances that are added to food for various purposes such as coloring, preservation, and emulsification.
In the case of PEG-20 Sorbitan Monooleate (Polysorbate 80), its E number, E433, reflects its role as an emulsifier and stabilizer in food products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a versatile compound product with numerous uses across various industries.
PEG-20 Sorbitan Monooleate (Polysorbate 80) has synthetic food additive with emulsifying and flavoring role.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used as a solvent for other food additives.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used in fine bakery products, sauces, desserts, confectioneries, fat emulsions for pastry, instant soups, ice, dietetic foods for body weight control.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is not recommended for vegetarians, because it can come from animal fats.
PEG-20 Sorbitan Monooleate (Polysorbate 80), or tween 80, is the abbreviation of “polyoxyethylene sorbitan monooleate”, is a synthetic compound derived from the esterification of sorbitan with ethylene oxide.
PEG-20 Sorbitan Monooleate (Polysorbate 80) belongs to the polysorbate family of surfactants, which are widely used as emulsifiers, solubilizers, and stabilizers in various industries, including food, pharmaceuticals, cosmetics, and personal care products.
PEG-20 Sorbitan Monooleate (Polysorbate 80)/Tween 80, or E433 is a synthetic compound with unique properties that make it valuable in various industries.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s CAS number is 9005-65-6, and its chemical formula is C64H124O26.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also known as Tween 80 and Polysorbate 80.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is obtained from animal and vegetable oils.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in water, insoluble in oil.
PEG-20 Sorbitan Monooleate (Polysorbate 80), full name polyoxyethylene sorbitan monooleate, also called polysorbate 80, is an emulsifier made from sorbitol, ethylene oxide and oleic acid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in water, ethanol, ethyl acetate and toluene.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s HLB value is 15.
PEG-20 Sorbitan Monooleate (Polysorbate 80), or Tween 80, is the abbreviation of “polyoxyethylene (20) sorbitan monooleate”, is a nonionic surfactant and emulsifier commonly used in food (with the European food additive number E433) and cosmetics mainly due to its ability to mix water-based and oil-based ingredients well (with a high approximate HLB value 15).
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a nonionic surfactant and emulsifier often used in pharmaceuticals, foods, and cosmetics.
This synthetic compound, PEG-20 Sorbitan Monooleate (Polysorbate 80), is a viscous, water-soluble yellow liquid.
USES and APPLICATIONS of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is utilized in a wide range of cosmetic products, including creams, lotions, serums, and even some makeup formulations, to create smooth textures and ensure proper dispersion of ingredients.
PEG-20 Sorbitan Monooleate (Polysorbate 80) being a nonionic surfactant is used in soaps and cosmetics (including eyedrops), or as solubilizer in mouthwashes.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a non-ionic surfactant and emulsifier find use in foods as emulsifier for salad dressings and chocolates, in cosmetics for preparing skin, facial cleansers and hair care products, and to disperse active ingredients in pharmaceuticals benefiting the pharmacological industry.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as emulsifiers and dispersing agents in medicinal products, defoamers and emulsifiers in foods, and surfactants for pharmaceuticals.
In industry, PEG-20 Sorbitan Monooleate (Polysorbate 80) is used mainly due to its emulsifying properties.
In addition, PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as a wetting agent or formulation stabilizer.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is mainly used in the cosmetics, textile industry and mining industry.
Products including PEG-20 Sorbitan Monooleate (Polysorbate 80) are shampoos, shower gels, moisturizing creams, face cleansing products, after sun creams, body lotions, foot creams, cleansing milks, liquid soaps, face creams etc.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is found in emulsion explosives as an emulsifier.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly used in various industries, including food, cosmetics, and pharmaceuticals, for its emulsifying, solubilizing, and stabilizing properties.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as emulsifier, stabiliser in a large range of foods including chewing gum, ice cream, soft drinks.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used in a wide range of detergents, pharmaceuticals and beauty and skin products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is an emulsifier derived from animal fatty acids, and natural oils and used as synthetic flavourings, surfactants, de foaming agents and dough conditioners.
PEG-20 Sorbitan Monooleate (Polysorbate 80) may increase the absorption of fat-soluble substances.
Beyond food applications, PEG-20 Sorbitan Monooleate (Polysorbate 80) is also utilized in various industrial settings, including:
Pharmaceuticals: PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a solubilizer and stabilizer in medications, particularly injectable formulations.
Cosmetics: PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as an emulsifier and surfactant in creams, lotions, and other personal care products.
Textiles: PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a wetting agent and lubricant.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a widely used emulsifier and surfactant in the food industry.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is created from sorbitan and ethylene oxide and is known for its ability to stabilize emulsions, improve texture, and enhance the shelf life of food products.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s versatility extends to cosmetics and pharmaceuticals, making it a staple in many industries.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly found in ice cream, salad dressings, and sauces, where it helps prevent ingredient separation and ensures a smooth consistency.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly used in food, cosmetics, pharmaceuticals, feed and industrial products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used in ice cream to make it smoother, easier to handle, and to increase its resistance to melting.
Processed Meats uses of PEG-20 Sorbitan Monooleate (Polysorbate 80): PEG-20 Sorbitan Monooleate (Polysorbate 80) can be found in certain processed meat products, such as sausages and luncheon meats, to improve their texture and moisture retention.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a solubilizer in pickles to distribute their flavors and colors.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as an antifoam in the fermentation process of some wines.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a thickener, antifoam, stabilizer and synthetic sweetener.
Pharmaceutical uses of PEG-20 Sorbitan Monooleate (Polysorbate 80): EP/USP/NF grade PEG-20 Sorbitan Monooleate (Polysorbate 80) can be used as an excipient that acts as an emulsifier, solubilizing agent or suspension stabilizer in various pharmaceutical formulations, such as in the dosage forms of solid, semi-solid and liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly used in food, cosmetics, pharmaceuticals, feed and industrial products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly used in food, cosmetic and pharmaceutical.
Others: PEG-20 Sorbitan Monooleate (Polysorbate 80) can be used as an emulsifier and stabilizer in various vaccines, as a lubricant in eye drops.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s versatility extends to cosmetics and pharmaceuticals, making it a staple in many industries.
-Other industries using PEG-20 Sorbitan Monooleate (Polysorbate 80):
In addition to cosmetic use, PEG-20 Sorbitan Monooleate (Polysorbate 80) is an excipient used to stabilize aqueous forms of medicinal products, for parenteral administration or for vaccination.
PEG-20 Sorbitan Monooleate (Polysorbate 80) helps to inhibit surface damage to a particle that is exposed to mechanical stress during transport and handling.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also one of the most common surfactants currently used in the formulation of protein-based biopharmaceuticals.
-Food uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as an emulsifier in foods, though research suggests it may "profoundly impact intestinal microbiota in a manner that promotes gut inflammation and associated disease states."
For example, in ice cream, PEG-20 Sorbitan Monooleate (Polysorbate 80) is added up to 0.5% (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting.
Adding PEG-20 Sorbitan Monooleate (Polysorbate 80) prevents milk proteins from completely coating the fat droplets.
This allows them to join in chains and nets, which hold air in the mixture, and provide a firmer texture that holds its shape as the ice cream melts.
-Dairy Products uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
*Ice cream and frozen desserts:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is often used as an emulsifier to improve the texture and prevent ice crystallization in ice cream and frozen desserts.
*Processed cheeses:
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be added to processed cheese products to enhance their meltability and texture.
-Baked Goods uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
*Bread and baked goods:
PEG-20 Sorbitan Monooleate (Polysorbate 80) can be found in certain types of bread and baked goods to improve their texture and shelf life.
*Cake mixes and frosting:
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be added to cake mixes and frosting to improve their consistency and stability.
-PEG-20 Sorbitan Monooleate (Polysorbate 80) in bread
Sauces and Dressings:
*Salad dressings:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly used as an emulsifier in salad dressings to prevent separation and achieve a smooth texture.
*Sauces and gravies:
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be added to sauces and gravies to improve their texture and stability.
-Confectionery uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
*Chocolate and candy coatings:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is sometimes used in chocolate and candy coatings to improve their flow properties and prevent blooming.
*Chewing gum:
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be added to chewing gum to enhance its texture and consistency.
-Other Processed Foods uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
*Instant noodles:
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be added to instant noodle products to prevent the noodles from sticking together and improve their texture.
*Margarine and spreads:
PEG-20 Sorbitan Monooleate (Polysorbate 80) may be used in margarine and spreads to achieve a smooth and spreadable consistency.
-Food industry uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as an emulsifier to improve the consistency and texture of products such as mayonnaise, cream, ice cream and baked goods.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used in the production of processed cheese and as a coating for fruits and vegetables.
-Cosmetics industry uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a surfactant, emollient, and viscosity-increasing agent in cosmetics and personal care products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is commonly added to lotions, creams, and makeup products to improve their texture, spreadability, and overall performance.
-Pharmaceutical industry uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a solubilizing agent to help increase the bioavailability and absorption of certain drugs.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used in the production of some vaccines and as a stabilizer for protein-based drugs.
-Health and beauty uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used as a surfactant in soaps and cosmetics (including eyedrops), or a solubilizer, such as in a mouthwash.
The cosmetic grade of PEG-20 Sorbitan Monooleate (Polysorbate 80) may have more impurities than the food grade.
-Medical uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a surfactant and solubilizer used in a variety of oral and topical pharmaceutical products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the making of the antiarrhythmic amiodarone.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used as an excipient in some European and Canadian influenza vaccines.
Influenza vaccines contain 2.5 μg of PEG-20 Sorbitan Monooleate (Polysorbate 80) per dose.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is found in many vaccines used in the United States, including the Janssen COVID-19 vaccine.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used as an emulsifier in the estrogen-regulating drug Estrasorb.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used in granulation for stabilization of drugs and excipients when IPA binding.
-Laboratory uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
Some mycobacteria contain a type of lipase (enzyme that breaks up lipid molecules); when these species are added to a mixture of PEG-20 Sorbitan Monooleate (Polysorbate 80) and phenol red, they cause the solution to change color, so this is used as a test to identify the phenotype of a strain or isolate.
On RODAC agar plates used in microbiological control, PEG-20 Sorbitan Monooleate (Polysorbate 80) counteracts disinfectants often found on sampled surfaces, thereby allowing the microbes found on these surfaces to grow
-Food use of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as an emulsifier in foods.
For example, in ice cream, PEG-20 Sorbitan Monooleate (Polysorbate 80) is added up to 0.5 % (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting.
Adding PEG-20 Sorbitan Monooleate (Polysorbate 80) prevents milk proteins from completely coating the fat droplets.
This allows them to join together in chains and nets, which hold air in the mixture, and provide a firmer texture that holds PEG-20 Sorbitan Monooleate (Polysorbate 80)'s shape as the ice cream melts.
PROPERTIES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) IN COSMETIC PRODUCTS:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a skin care ingredient used in cosmetics and personal care products to improve their texture.
PEG-20 Sorbitan Monooleate (Polysorbate 80) gives the cosmetics an appropriate, fluffy consistency.
While the texture of PEG-20 Sorbitan Monooleate (Polysorbate 80) is primarily sensory.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also important that it spreads easily, delivering the key ingredients evenly across the skin.
PEG-20 Sorbitan Monooleate (Polysorbate 80) effectively supports the stability of creams, lotions and gels, especially those that are cold processed, stimulating oils and water to bind easily.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a surfactant, emulsifier and solvent, helping to create smooth, easy-to-apply skin and body care products.
As an emulsifier, PEG-20 Sorbitan Monooleate (Polysorbate 80) helps to mix ingredients and prevent them from separating.Its solubilizing properties are used in cosmetic preparations.
As a surfactant, PEG-20 Sorbitan Monooleate (Polysorbate 80) increases the solubility of one substance in another.
A substance which would not normally be dissolved in a given solution can be dissolved in the presence of PEG-20 Sorbitan Monooleate (Polysorbate 80).
Thanks to this, PEG-20 Sorbitan Monooleate (Polysorbate 80) becomes effective, for example, to wash off impurities from the skin surface with the use of face washing gels containing ethoxylated sorbitan monooleate.
FUNCTIONS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) IN COSMETIC PRODUCTS:
*emulsifier,
*solvent,
*dispersant,
*stabilizing factor.
GENERAL CHARACTERISTICS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a hydrophilic, nonionic surfactant.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a thick yellow liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is characterized by high viscosity.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is very soluble in water, lower aliphatic alcohols and benzene, while it is poorly soluble in fats.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is biodegradable in the natural environment.
WHAT IS PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) USED FOR?
PEG-20 Sorbitan Monooleate (Polysorbate 80) is widely used in various industries, including cosmetics, due to its versatile properties and benefits.
PEG-20 Sorbitan Monooleate (Polysorbate 80) serves as an effective emulsifier and solubilizer, allowing for the blending of water and oil-based ingredients in cosmetic formulations.
This makes PEG-20 Sorbitan Monooleate (Polysorbate 80) valuable in creating stable emulsions, such as creams, lotions, and serums, ensuring proper dispersion of active ingredients.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also utilized in haircare products to enhance the spreadability and distribution of conditioning agents.
In addition, PEG-20 Sorbitan Monooleate (Polysorbate 80) finds applications in cosmetic products like foundations, eyeshadows, and lipsticks, where it aids in the uniform dispersion of pigments, resulting in smooth and consistent application.
ORIGIN OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is produced through the ethoxylation process, where sorbitol, a sugar alcohol derived from natural sources, is reacted with ethylene oxide.
This reaction creates a polyethylene glycol chain attached to the sorbitol molecule, resulting in the formation of PEG-20 Sorbitan Monooleate (Polysorbate 80).
WHAT DOES PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) DO IN A FORMULATION?
*Emulsifying
*Surfactant
SAFETY PROFILE OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is generally considered safe for use in cosmetics.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is not considered toxic when used in recommended concentrations.
However, some individuals with sensitive skin may experience mild skin irritation, therefore, a patch test is necessary.
Further, PEG-20 Sorbitan Monooleate (Polysorbate 80) is generally considered vegan as it is derived from natural sources and does not contain animal-derived ingredients.
ALTERNATIVES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
*POLYSORBATE 20,
*CETEARETH20,
*GLYCERYL STEARATE
PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) IN COSMETICS:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a versatile ingredient widely used in cosmetic and personal care products for its emulsifying, solubilizing, and stabilizing properties.
As an emulsifier, PEG-20 Sorbitan Monooleate (Polysorbate 80) facilitates the blending of oil and water-based ingredients, ensuring stable and uniform formulations in products like creams, lotions, and serums.
Additionally, PEG-20 Sorbitan Monooleate (Polysorbate 80) serves as a solubilizing agent, enabling the incorporation of hydrophobic substances into aqueous solutions, thus enhancing the overall solubility and efficacy of cosmetic products.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s role in texture enhancement contributes to the luxurious consistency of formulations, providing consumers with a smooth and pleasant sensory experience.
Furthermore, PEG-20 Sorbitan Monooleate (Polysorbate 80) plays a crucial role in stabilizing cosmetic formulations, preventing ingredient separation and maintaining product integrity over time, thereby extending shelf life and ensuring efficacy.
Commonly found in various skin care and hair care products,
PEG-20 Sorbitan Monooleate (Polysorbate 80) enhances the performance of these formulations, contributing to their effectiveness and consumer satisfaction.
PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) IN PHARMACEUTICAL:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a key ingredient in the pharmaceutical industry due to its versatile properties.
Acting as a solubilizing agent, PEG-20 Sorbitan Monooleate (Polysorbate 80) enhances the solubility of poorly water-soluble drugs, improving their bioavailability and efficacy.
Additionally, PEG-20 Sorbitan Monooleate (Polysorbate 80) serves as an emulsifier, ensuring the uniform dispersion of oil and water-based ingredients in formulations like suspensions and ointments.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s stabilizing effects prevent particle aggregation and maintain formulation integrity, extending shelf life.
Furthermore, PEG-20 Sorbitan Monooleate (Polysorbate 80) plays a vital role in drug delivery systems, facilitating drug penetration and absorption.
Its versatility and compatibility make PEG-20 Sorbitan Monooleate (Polysorbate 80) an essential excipient in various dosage forms, from oral medications to topical creams, contributing to the effectiveness and reliability of pharmaceutical products.
FOOD USES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
According to the EFSA, PEG-20 Sorbitan Monooleate (Polysorbate 80) is an approved food additive used as an emulsifier, stabilizer, and dispersing agent.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s commonly found in a variety of food products, including:
*Baked goods:
PEG-20 Sorbitan Monooleate (Polysorbate 80) improves texture and volume.
*Ice cream and frozen desserts:
PEG-20 Sorbitan Monooleate (Polysorbate 80) prevents ice crystal formation and creates a smooth texture.
*Sauces and dressings:
PEG-20 Sorbitan Monooleate (Polysorbate 80) stabilizes emulsions and prevents separation.
*Fat-based spreads:
PEG-20 Sorbitan Monooleate (Polysorbate 80) improves spreadability.
*Flavourings:
PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as a solubilizer for oil-based flavours in water-based products.
WHAT ARE THE USES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80)?
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a super emulsifier and stabilizer that mixes two or more not compatible ingredients not separate, usually oil and water.
PEG-20 Sorbitan Monooleate (Polysorbate 80) ia commonly used in food and cosmetics, also with a little application in medicines, vaccines and others.
*Food
Food grade PEG-20 Sorbitan Monooleate (Polysorbate 80) helps water-based liquids and oils-based ingredients mixed together easily.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s common food applications are in ice cream, pickles, vitamins and sauce.
Let’s see PEG-20 Sorbitan Monooleate (Polysorbate 80)'s various functions in food.
*Ice cream
Provide a creamy texture
Hold fat and water together (or maintain the shape) very well
Prevent ice crystals formation
Make ice cream resistant to melt
*Pickles
As a solubilizer to disperse food flavors and colors.
*Vitamin supplements
As a solubilizing and dispersing agent in fat-soluble vitamins and vitamin-mineral preparations.
*Butter sauce
PEG-20 Sorbitan Monooleate (Polysorbate 80) produces the creamy sauce; enables butter and water not separate; makes the milk solids, salts, flavors, colors and other ingredients distributed evenly in the sauce.
*Cosmetics
Cosmetic grade PEG-20 Sorbitan Monooleate (Polysorbate 80) functions as a denaturant, emulsifying, surfactant in cosmetics and personal care products to help blend oil and water.
For the strong hydrophilicity, PEG-20 Sorbitan Monooleate (Polysorbate 80) can distribute colors (e.g. incorporate mica), fragrances, oils and other ingredients evenly in bath bombs, creams and soaps.
The following products may contain PEG-20 Sorbitan Monooleate (Polysorbate 80):
*Bath bombs
*Shampoo
*Body butter
*Soap
HOW IS PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) MADE?
The synthesis of PEG-20 Sorbitan Monooleate (Polysorbate 80) is a meticulously controlled, multi-step process.
PEG-20 Sorbitan Monooleate (Polysorbate 80) begins with the esterification of sorbitol, a hexavalent sugar alcohol, using fatty acids derived mainly from natural oils such as olive oil.
Esterification, a chemical process involving the reaction between an organic acid (with a carboxyl group, -COOH) and an alcohol (with a hydroxyl group, -OH), leads to the formation of sorbitan esters in the initial chemical reaction.
The sorbitan esters go through through ethoxylation, a key step involving the introduction of ethylene oxide under catalyst influence.
The addition of ethylene oxide imparts hydrophilic (water-attracting) properties to the molecule, making it more soluble in water.
Following this, purification steps employing distillation and filtration methods are implemented to remove any residual reactants and impurities.
This is a critical step as the presence of impurities can affect the properties and performance of the final product.
The final manufacturing stage involves neutralization to attain the desired pH level.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a nonionic surfactant, and its stability and effectiveness can be influenced by pH.
Neutralization helps to stabilize the molecule and ensures that PEG-20 Sorbitan Monooleate (Polysorbate 80) remains compatible with a wide range of other ingredients commonly used in various products, including pharmaceuticals, cosmetics, and food.
BENEFITS AND USES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
You can find PEG-20 Sorbitan Monooleate (Polysorbate 80) in watery concoctions like room sprays, body sprays, and hand washes.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used to disperse oils evenly so they don’t separate in shampoos, conditioners, face washes, lipsticks, etc.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is the reason behind the creaminess of your products.
PEG-20 Sorbitan Monooleate (Polysorbate 80) boosts rinse off and adds extra strength to your other surfactants.
Seldom PEG-20 Sorbitan Monooleate (Polysorbate 80) is used as a food additive in wines and ice-creams.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is used in sauces to keep their texture smooth.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also used to improve the consistency of gel capsules and to make the pills disperse in the stomach.
HOW PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) WORKS:
PEG-20 Sorbitan Monooleate (Polysorbate 80) works by breaking the water tension of the surface to allow the lifting of dirt and oil.
PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as an emulsifier to improve the consistency of any product.
PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as a solubilizer that blends all the ingredients.
CONCENTRATION AND SOLUBILITY OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
As a food additive, PEG-20 Sorbitan Monooleate (Polysorbate 80) is added up to 0.5% concentration.
In bath and body products, the recommended concentration of PEG-20 Sorbitan Monooleate (Polysorbate 80) is up to 2%.
For other industrial purposes, the concentration of PEG-20 Sorbitan Monooleate (Polysorbate 80) can go up to 20%.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in water.
HOW TO USE PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
To the heated oil phase add PEG-20 Sorbitan Monooleate (Polysorbate 80).
Stir and dissolve PEG-20 Sorbitan Monooleate (Polysorbate 80) completely.
Once PEG-20 Sorbitan Monooleate (Polysorbate 80) cools down to room temperature add water.
Keep PEG-20 Sorbitan Monooleate (Polysorbate 80) agitating constantly until an emulsion forms.
IS PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) SAFE?
PEG-20 Sorbitan Monooleate (Polysorbate 80) is generally recognized as safe (GRAS) for use in food and pharmaceutical products by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).
However, some individuals may be sensitive or allergic to PEG-20 Sorbitan Monooleate (Polysorbate 80), and its safety in long-term or high-dose exposure scenarios continues to be evaluated.
BENEFICIAL PROPERTIES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) offers several beneficial properties in food and other applications:
*Emulsification:
Effectively blends oil and water phases, creating stable emulsions.
*Stabilization:
PEG-20 Sorbitan Monooleate (Polysorbate 80) helps prevent separation and maintain product homogeneity.
*Improved texture and mouthfeel:
PEG-20 Sorbitan Monooleate (Polysorbate 80) contributes to a smoother, more desirable texture in food products.
*Increased shelf life:
PEG-20 Sorbitan Monooleate (Polysorbate 80) enhances product stability and extends shelf life.
CLASS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
*Emulsifiers,
*Stabilisers,
*Thickeners,
*Gelling Agents,
HOW PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) IS MANUFACTURED?
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a compound of a specific fatty acid and ethylene oxide (average 20% ethylene oxide per molecule of polysorbate 80).
20 polymerized ethylene oxide ) is an ethoxylated sorbitan ester produced by the reaction between.
The fatty acid used for the production of PEG-20 Sorbitan Monooleate (Polysorbate 80) is oleic acid.
Oleic acid is a fatty acid found in animal and vegetable oils.
There are generally two steps in the production process of PEG-20 Sorbitan Monooleate (Polysorbate 80); Esterification between oleic acid and sorbitol to obtain sorbitan esters.
Condensation sorbitan esters with ethylene oxide.
PEG-20 Sorbitan Monooleate (Polysorbate 80) can also be produced by first reacting sorbitol and ethylene oxide and then esterifying with oleic acid .
This production step is as follows: Sorbitol is partially dehydrated to obtain a mixture of sorbitol and sorbitan, Ethylene oxide is added to the mixture to obtain sorbitan polyethylene ether, Reacted with oleic acid .
PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) PHYSICAL AND CHEMICAL PROPERTIES:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in water, and is soluble in most solvents such as ethanol, methanol, ethyl acetate and toluene.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a golden viscous liquid.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a nonionic surfactant, meaning it has a neutral charge.
PRODUCTION PROCESS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is produced by the ethoxylation of sorbitan monooleate.
This involves reacting sorbitol with oleic acid to form sorbitan monooleate.
Subsequently, ethylene oxide is added to the sorbitan monooleate, resulting in the formation of polyoxyethylene chains attached to the sorbitan molecule.
The length of these chains and the degree of ethoxylation influence the final properties of the PEG-20 Sorbitan Monooleate (Polysorbate 80).
FUNCTIONS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) IN FOOD:
*As emulsifier
In the emulsification process, PEG-20 Sorbitan Monooleate (Polysorbate 80) aligns at the interface between water and oil phases.
The hydrophilic heads extend into the water, while the lipophilic tails immerse into the oil, creating micelles—tiny structures that encapsulate and disperse oil droplets within the water.
This arrangement prevents the oil droplets from coalescing and separating, resulting in a stable and homogenous emulsion.
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a common ingredient in baked goods, salad dressings, and ice cream.
For example, PEG-20 Sorbitan Monooleate (Polysorbate 80) contributes to the smooth and creamy texture of ice cream, which enhances the desired mouthfeel.
A complex blend of water, fat, sugar, and other substances makes up ice cream.
These ingredients may have a tendency to separate in the absence of an emulsifier, giving the finished product an undesirable texture.
Particularly the fat and water components naturally oppose one another, which leads to the production of ice crystals and an unsatisfactory consistency.
PEG-20 Sorbitan Monooleate (Polysorbate 80) facilitates the coexistence of fat and water molecules by acting as a bridge.
As a result, the ice cream keeps its uniform composition.
*As anti-foaming agent
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s anti-foaming properties is helpful in the production of carbonated drinks and beer
One of PEG-20 Sorbitan Monooleate (Polysorbate 80)’s important properties is its capacity to lower surface tension, which aids in the destabilization of foam bubbles.
Surface tension is a liquid attribute caused by the cohesive interactions between molecules at the liquid’s surface.
Foam is a mixture of gas bubbles scattered throughout a liquid or solid.
Excessive foam can make industrial processes less effective.
For example, uncontrolled foam formation in the food and beverage industry can result in uneven mixing, erroneous measurements, and variations in the quality of the finished product.
This is particularly true during mixing, blending, and cooking.
For example, during the manufacture of candies and aerated treats, foaming may lead to the formation of undesirable air pockets in the final product.
With the addition of PEG-20 Sorbitan Monooleate (Polysorbate 80), foaming is kept to a minimum during cooking, ensuring that confections set correctly.
PEG-20 Sorbitan Monooleate (Polysorbate 80)’s anti-foaming properties also find application in the beverage industry, particularly in the production of carbonated drinks and beer.
Excessive foam in these products can lead to inefficiencies in filling and packaging, as well as affect the sensory characteristics of the final beverage.
*As wetting agent
PEG-20 Sorbitan Monooleate (Polysorbate 80) is not only as an effective anti-foaming agent, and emulsifier, but also as a wetting agent (or surfactant).
Wetting agents help overcome issues related to poor dispersion and solubility of certain components in food formulations.
With its capacity to enhance the wetting properties of specific ingredients, PEG-20 Sorbitan Monooleate (Polysorbate 80) facilitates their seamless incorporation into food products.
This property proves particularly beneficial in various applications, ranging from baked goods to sauces and dressings.
Flour, a fundamental ingredient in baking, tends to form clumps and resist hydration.
Incorporating PEG-20 Sorbitan Monooleate (Polysorbate 80) combats this issue by reducing the surface tension between flour particles and liquid components.
This results in improved dispersion, allowing for a smoother, lump-free batter or dough.
The even wetting of flour helps achieve a consistent texture and uniformity in the final baked product.
The versatility of PEG-20 Sorbitan Monooleate (Polysorbate 80) as a food additive makes it a preferred choice for manufacturers seeking multifunctional ingredients to streamline their processes.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s nonionic nature allows it to interact effectively with a diverse array of ingredients without compromising the sensory attributes of the final product.
PROPERTIES OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
*Appearance
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a viscous, lemon to amber-colored oily liquid at 25°C.
*Hydrophilic – Lipophilic Balance (HLB)
15, gives oil-in-water emulsions, O/W
*Viscosity
PEG-20 Sorbitan Monooleate (Polysorbate 80) is also a viscosity agent with the viscosity 300–500 centistokes (@25°C).
*Solubility
In Water
PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in water due to the long polyoxyethylene chains.
*In Organic Solvents
PEG-20 Sorbitan Monooleate (Polysorbate 80) is soluble in most solvents, such as ethanol, methanol, ethyl acetate and toluene.
HOW IS PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) MADE?
PEG-20 Sorbitan Monooleate (Polysorbate 80) is synthesized through a chemical reaction involving sorbitan monostearate and ethylene oxide.
Here's an overview of the process:
1. Starting Materials
The primary starting material for the synthesis of PEG-20 Sorbitan Monooleate (Polysorbate 80) is sorbitan monostearate, which is derived from sorbitol, a sugar alcohol.
Sorbitan monostearate is a fatty acid ester with a hydrophilic (water-attracting) sorbitan head and a lipophilic (oil-attracting) stearate tail.
2. Ethoxylation
Sorbitan monostearate undergoes a process called ethoxylation, which involves the addition of ethylene oxide molecules to the molecule.
Ethylene oxide is a reactive compound that reacts readily with the hydroxyl groups present in sorbitan monostearate.
3. Polymerization
As ethylene oxide molecules react with sorbitan monostearate, they form chains of repeating ethylene oxide units, leading to the formation of a polyethylene glycol (PEG) chain.
This polymerization process results in the formation of PEG-20 Sorbitan Monooleate (Polysorbate 80), which is a mixture of sorbitan monoester ethoxylates with varying degrees of ethoxylation.
4. Purification
After the synthesis, the crude PEG-20 Sorbitan Monooleate (Polysorbate 80) product undergoes purification steps to remove impurities and by-products.
This may involve processes such as filtration, distillation, or chromatography to ensure the final product meets quality standards and regulatory requirements.
5. Packaging and Distribution
Once purified, the PEG-20 Sorbitan Monooleate (Polysorbate 80) is typically packaged into containers suitable for transportation and distribution to manufacturers in various industries, including food, pharmaceuticals, cosmetics, and personal care products.
In short, the synthesis of PEG-20 Sorbitan Monooleate (Polysorbate 80) involves the ethoxylation of sorbitan monostearate, resulting in the formation of a polyethylene glycol chain attached to the sorbitan molecule.
This process yields a versatile emulsifier with a wide range of applications across different sectors.
KEY PROPERTIES AND STRUCTURAL CHARACTERISTICS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
Here are some of its key properties and structural characteristics:
*Hydrophilic-Lipophilic Balance (HLB) :
PEG-20 Sorbitan Monooleate (Polysorbate 80) has a moderate HLB value, typically ranging from 15 to 16.
This balance of hydrophilicity and lipophilicity allows PEG-20 Sorbitan Monooleate (Polysorbate 80) to act as an effective emulsifier, facilitating the formation of stable oil-in-water emulsions.
*Emulsifying Properties:
As an emulsifier, PEG-20 Sorbitan Monooleate (Polysorbate 80) lowers the interfacial tension between oil and water phases, allowing them to mix more easily and form stable emulsions.
PEG-20 Sorbitan Monooleate (Polysorbate 80) accomplishes this by adsorbing to the interface between the two phases, with its hydrophilic head facing the water phase and its lipophilic tail facing the oil phase.
*Solubilizing Ability:
PEG-20 Sorbitan Monooleate (Polysorbate 80) exhibits solubilizing properties, enabling it to dissolve hydrophobic (water-insoluble) substances in aqueous solutions.
This makes PEG-20 Sorbitan Monooleate (Polysorbate 80) useful in pharmaceutical formulations for improving the solubility and bioavailability of poorly water-soluble drugs.
*Stabilizing Effect:
In addition to its emulsifying and solubilizing properties, PEG-20 Sorbitan Monooleate (Polysorbate 80) acts as a stabilizer in formulations, preventing the aggregation or precipitation of particles and enhancing the stability of suspensions and emulsions over time.
*Compatibility:
PEG-20 Sorbitan Monooleate (Polysorbate 80) is compatible with a wide range of other ingredients, including oils, surfactants, and hydrophilic and hydrophobic substances.
This compatibility makes PEG-20 Sorbitan Monooleate (Polysorbate 80) versatile and allows for its incorporation into diverse formulations across multiple industries.
CHEMISTRY OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80) is derived from polyethoxylated sorbitan and oleic acid.
The hydrophilic groups in PEG-20 Sorbitan Monooleate (Polysorbate 80) are polyethers also known as polyoxyethylene groups, which are polymers of ethylene oxide.
In the nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case, the oleic acid (see polysorbate for more detail).
The full chemical names for PEG-20 Sorbitan Monooleate (Polysorbate 80) are:
Polyoxyethylene (80) sorbitan monooleate
(x)-sorbitan mono-9-octadecenoate poly(oxy-1,2-ethanediyl)
The critical micelle concentration of PEG-20 Sorbitan Monooleate (Polysorbate 80) in pure water is reported as 0.012 mM.
IS PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) SAFE TO EAT?
Yes, PEG-20 Sorbitan Monooleate (Polysorbate 80) has been approved as a safe ingredient by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).
FDA
PEG-20 Sorbitan Monooleate (Polysorbate 80) is a multifunctional ingredient that may be safely used in food as an emulsifier, defoamer, solubilizing and dispersing agent, surfactant, wetting agent and adjuvant.
The following food may contain it and with the maximum use levels:
*Ice cream 0.1%
*Yeast defoamer 4ppm
*Pickles and pickled products 500 ppm
*Vitamin preparations, the maximum intake of polysorbate 80 per day 175-475 milligrams
*Shortenings and edible oils 1% (with polysorbate 60 or not) cottage cheese 0.008%
*Whipped edible oil topping 0.4% with/not sorbitan monostearate/polysorbate 60/polysorbate 65
*Gelatin desserts and mixes 0.082%
*Barbecue sauce 0.005%
EFSA
PEG-20 Sorbitan Monooleate (Polysorbate 80) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “Additives other than colours and sweeteners”.
Approved uses of PEG-20 Sorbitan Monooleate (Polysorbate 80):
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s application is listed together with other polysorbates: polysorbate 20 (E432), 40(E434), 60(E435), 65(E436), with the maximum usages 500-1000mg/kg.
PEG-20 Sorbitan Monooleate (Polysorbate 80)'s usage is “quantum satis” in power or liquid food supplements (not for infants and young children).
The following food may contain PEG-20 Sorbitan Monooleate (Polysorbate 80):
*Flavoured fermented milk products
*Milk and cream analogues
*Fat emulsions for baking
*Sugar confectionery
*Chewing gum
*Decorations, coatings and fillings
*Fine bakery wares
*Soups, sauces
*Desserts
HOW IS PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) MADE?
Polysorbates (20,40, 60, 65, 80) are the ethoxylated sorbitan esters which are manufactured by the reaction among sorbitol, a specific fatty acid, and ethylene oxide (an average of 20 polymerized ethylene oxide per molecule of PEG-20 Sorbitan Monooleate (Polysorbate 80)).
The fatty acid used for the production of PEG-20 Sorbitan Monooleate (Polysorbate 80) is oleic acid.
Let’s see its two raw materials.
**Sorbitol
It is a sugar alcohol produced by the reduction reaction (or hydrogenation) of glucose which is obtained from maize or tapioca starch. Know more Sorbitol here.
**Oleic Acid
Oleic acid is a monounsaturated fatty acid naturally found in animal fats & oils and vegetable oils.
Commercial food grade oleic acid is not pure and is a mixture of several fatty acids.
Like other fatty acids, oleic acid also present in nature commonly in the form of triglycerides.
The following are the vegetable oils high with oleic acid:
*Olive oil
*Pecan oil
*Canola oil
*Peanut oil
*Macadamia oil
*Sunflower oil
*Grape seed oil
*Sea buckthorn oil
*Sesame oil
*Poppyseed oil
MANUFACTURING PROCESS OF PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
According to the FDA, there are generally two steps in the manufacturing process of PEG-20 Sorbitan Monooleate (Polysorbate 80):
Esterification between oleic acid and sorbitol to obtain sorbitan esters.
Condensation sorbitan esters with ethylene oxide.
PEG-20 Sorbitan Monooleate (Polysorbate 80) can also be produced by reacting sorbitol and ethylene oxide first then esterified with oleic acid, the following are the brief flow chart:
*Obtaining the mixture of sorbitol and sorbitan by partially dehydrating sorbitol.
*Adding ethylene oxide to the mixture to obtain sorbitan polyethylene ether.
*Reacting it with oleic acid.
WHAT ARE PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80) (AFTER PPOLYSORBATE) AND 20 (FOLLOWING POLYOXYETHYLENE) STANDS FOR?
80 refers to the type of fatty acid attached to the polyoxyethylene sorbitan part of the molecule, here it is monooleate or oleic acid.
20 means the total number of oxyethylene –(CH2CH2O)–groups in the molecule.
PHYSICAL and CHEMICAL PROPERTIES of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
pH: 11.0
Solubility: Soluble in water
Viscosity: High
INCI: Coco-Glucoside
CAS Number: 141464-42-8
Potential Applications: Shampoo, hand wash, body wash, face wash, bubble bath, solid bars
Usage: Up to 25%
Solubility: Water Soluble
Palm Free: Yes
Vegan: Yes
IUPAC Name: D-Glucopyranose, oligomeric, C10-16-alkyl glycosides
INCI Name: Coco Glucoside
CAS Numbers: 110615-47-9, 68515-73-1
Molar Mass: Not specified (a mixture)
Density: 1.15 g/mL at 20°C
Solubility: Miscible with water and most polar solvents
Texture: Slippery, detergenty
Scent: Characteristically detergenty
Active Surfactant Matter: 55%
pH: 11.5–12.5
Charge: Non-ionic
Solubility: Water
Molecular Weight: 604.81300
Exact Mass: 604.41900
EC Number: 500-019-9
DSSTox ID: DTXSID0021175
Color/Form: Yellow to orange colored, oily liquid
Lemon- to amber-colored, oily liquid
HScode: 2932999099
PSA: 133.14000
XLogP3: 4.46260
Appearance: Polysorbate 80 is an amber-colored viscous liquid.
pH (5% aqueous solution) 5-7.
Faint odor and bitter taste.
Density: 1.06-1.10 g/cm3
Melting Point: -21ºC
Boiling Point: > 100ºC
Flash Point: >110ºC
Refractive Index: 1.471-1.473
Water Solubility: H2O: 5-10 g/100 mL at 23 ºC
Storage Conditions: Store at RT.
Vapor Pressure: <1 mm Hg (20 °C)
Toxicity: LD50 in mice, rats (ml/kg): 7.5, 6.3 i.p. (Varma)
PH: pH of 5% aqueous solution between 6 and 8
Experimental Properties: Hydroxyl radical reaction rate constant = 3.35X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions: Water soluble.
Reactive Group: Ethers
Reactivity Profile: POLYSORBATE 80 is incompatible with strong alkalis and oxidizers.
Vapor Pressure： <1 mm Hg ( 20 °C)
PH： pH of 5% aqueous solution between 6 and 8
Appearance Form: liquid
Color: yellow
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: > 113 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 1,33 hPa at 20 °C
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties No data available
Oxidizing properties: No data available
Other safety information: No data available
Acid value: ≤2.0(mg KOH/g)
Saponification value: 45-55(mg KOH/g)
Hydroxyl value: 65~80(mg KOH/g)
Moisture: ≤3.0(w/%)
Residue on ignition: ≤0.25(w/%)
Oxyethylen: 65~69.5(w/%)
Color: Yellow to Amber
Content And Storage: Indoors +20°C
Density: 1.0800 g/mL
Molecular Formula: (C2H4O)x(C2H4O)z(C2H4O)y(C2H4O)wC24H44O6
MDL Number: MFCD00082107
InChI Key: HDTIFOGXOGLRCB-KTKRTIGZNA-N
SMILES: CCCCCCCCC=C/CCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO
IUPAC Name: 2-{2-[3,5-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl (9E)-octadec-9-enoate
Molecular Weight (g/mol): 604.82
Solubility: Solubility in water: 100g/L.
Other solubilities: 100g/L isopropyl alcohol, 10g/L xylene,
insoluble in propylene glycol and mineral oil
Form: Viscous Liquid
Molecular Weight: 604.8
Molecular Formula: C32H60O10
Melting Point: -21°C
Flash Point: >110°C
Purity: 99%+
Density: 1.064
Appearance: Clear Colourless Oil
Storage: Room Temperature
Assay: 0.99
Refractive Index: 1.471-1.473
Stability: Stable under normal temperatures and pressures.
Viscosity: 300–500 centistokes (@25°C)
Formula: C64H124O26
Molar Mass: 1310 g/mol
Appearance: Powder
Monoglyceride Content: Minimum 40%
Water Content: Maximum 1.0%
Acid Value (mg KOH/g): Maximum 10.0
Saponification Value (mg/g): Range of 130-160
Molar mass: 1310 g/mol
Appearance: Amber colored liquid, Amber viscous grease
Density: 1.102 g/mL, oily liquid
Boiling point: > 100°C
Solubility in water: 100 mL/L
Solubility in other solvents:
soluble in ethanol
cottonseed oi, corn oil
ethyl acetate, methanol, toluene
Viscosity: 300–500 centistokes (@25°C)
Hydroxyl value: 65~82
Saponification number: 43~55
Acid value: ≤2
PSA： 133.14000
XLogP3： 4.46260
Appearance：: Polysorbate 80 is an amber-colored viscous liquid.
pH: (5% aqueous solution) 5-7.
Faint odor and bitter taste. (NTP, 1992)
Density： 1.06-1.10 g/cm3
Melting Point： -21ºC
Boiling Point： > 100ºC
Flash Point： >110ºC
Refractive Index： 1.471-1.473
Water Solubility： H2O: 5-10 g/100 mL at 23 ºC
Storage Conditions： Store at RT.
Chemical Formula: C64H124O26
Molar Mass: 1310 g/mol
Appearance: Amber-colored oil
Density: 1.102 g/mL
Boiling Point: > 100°C
Solubility in Water: 100 mL/L
Solubility in Other Solvents: It is soluble in ethanol,
cottonseed oil, corn oil, ethyl acetate, methanol, and toluene.
Appearance: pale yellow to orange oily liquid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 1.06400 @ 25.00 °C.
Refractive Index: 1.47200 @ 20.00 °C.
Boiling Point: 695.00 to 696.00 °C. @ 760.00 mm Hg (est)
Acid Value: 80.00 max. KOH/g
Flash Point: 235.00 °F. TCC (112.78 °C.)
logP (o/w): 4.392 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in: alcohol, oils, water, ethyl acetate, methanol, toluene, water, 0.01999 mg/L @ 25 °C (est)
Insoluble in: mineral oil, petroleum ether
FIRST AID MEASURES of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.
FIRE FIGHTING MEASURES of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available
EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
STABILITY and REACTIVITY of PEG-20 SORBITAN MONOOLEATE (POLYSORBATE 80):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available
