Quick Search
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is a nonionic surfactant and emulsifier used to stabilize oil-in-water emulsions, produced from sorbitol, palmitic acid, and ethylene oxide.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) helps disperse oils, flavors, colors, fragrances, and active ingredients in water-based formulations and maintains the uniform consistency and stability of mixtures that contain ingredients that would not normally mix, such as water and fats.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434)'s high HLB value of approximately 15.6 makes it suitable for food, cosmetic, pharmaceutical, and industrial emulsion systems.
CAS Number: 9005-66-7
EC Number: 500-020-4
Molecular Formula: C62H122O26
Molecular Weight: 1284.60 g/mol
Synonyms: Polysorbate 40, E434, INS 434, Polyoxyethylene Sorbitan Monopalmitate, Polyoxyethylene(20) Sorbitan Monopalmitate, PEG-20 Sorbitan Monopalmitate, Sorbitan Monopalmitate Ethoxylated, Ethoxylated Sorbitan Monopalmitate, Sorbimacrogol Palmitate 300, Sorbitan Polyethoxy Monopalmitate, Tween 40, FDA UNII STI11B5A2X
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is an organic chemical compound that is an ester of palmitic acid and polyoxyethylene sorbitol, belonging to the polysorbate family and commonly used in food, cosmetics, pharmaceuticals, and industrial formulations.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is a fat derivative type emulsifier that prevents the separation of different ingredients in a formulation, maintains product efficacy, and as a dispersing agent helps distribute pigments and active ingredients evenly.
At room temperature, Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is in the form of a yellow to orange viscous liquid or paste.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is soluble in water, ethanol, ethyl acetate, and toluene.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is a mild and non-irritating surfactant widely used in the beauty industry for gentle yet effective cleansing of skin and hair by reducing surface tension.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) may also function as a mild conditioning and anti-static agent, particularly in hair care products.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is mainly used in ice cream, sauces and dressings, baked goods, desserts, and confectionery as a stabilizer to prevent the separation of fat and water, and also prolongs the shelf life of food and improves its appearance.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is used in cosmetics to improve the consistency and distribution of other ingredients, and in pharmaceuticals as a component of carriers for medicinal substances.
Uses of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is used as an emulsifier, solubilizer, stabilizer, wetting agent, dispersing agent, foaming agent, lubricant, and antistatic agent.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is used in food products including sauces, mayonnaise, coffee creams, ice cream, baked goods, and desserts to combine oil and water phases and support uniform ingredient distribution.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is used in facial cleansers, shampoos, moisturizers, lotions, liquid foundations, mascaras, and body sprays as a mild surfactant that aids cleansing, prevents ingredient separation, and provides a smooth, non-greasy feel.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) helps distribute pigments and active ingredients evenly in makeup formulations, and acts as an anti-static agent in conditioning hair care products.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is used in pharmaceutical formulations to disperse or solubilize oily ingredients in water-based systems and as a component of drug delivery carriers.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is used as an emulsifier, wetting agent, and chemical intermediate in various industrial applications.
Benefits or Advantages of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) has numerous applications including acting as an emulsifier, wetting agent, foaming agent, lubricant, solubilizer, antistatic agent, dispersant, and chemical intermediate across food, cosmetic, pharmaceutical, and industrial sectors.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is a nonionic surfactant with a neutral charge, making it compatible with a broad range of formulation systems including ionic, cationic, and anionic components.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) has an HLB value of approximately 15.6, providing strong oil-in-water emulsifying performance suited to food and personal care formulations.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) has stabilizing properties that prevent the separation of ingredients in foods and cosmetic formulations, extending product shelf life and maintaining visual appeal.
Features of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is a pale yellow to orange viscous oily liquid or paste with a mild characteristic odor.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) has a specific gravity of approximately 1.083 at 25 degrees C, a refractive index of approximately 1.470 at 20 degrees C, and a flash point above 110 degrees C.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is soluble or dispersible in water, and soluble in ethanol, ethyl acetate, and toluene.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) has an HLB value of approximately 15.6 and an ionic character that is nonionic.
Chemical Properties of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is produced by esterification of sorbitan with palmitic acid (C16 fatty acid) followed by ethoxylation with approximately 20 moles of ethylene oxide per molecule.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) has a molecular formula of C62H122O26 and a molecular weight of 1284.60 g/mol.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is chemically stable under recommended storage and handling conditions and does not react dangerously under normal use conditions.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) may react with strong oxidizing agents, strong acids, or strong bases, and thermal decomposition or combustion may produce carbon monoxide, carbon dioxide, and irritating organic fumes.
Production and Chemical Reactions of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is produced by first dehydrating sorbitol to form sorbitan, then esterifying with palmitic acid (C16 fatty acid) in the presence of a catalyst, and finally ethoxylating the resulting sorbitan palmitate with approximately 20 moles of ethylene oxide.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) production is carried out under controlled conditions to ensure consistent HLB value, saponification value, hydroxyl value, and acid value within specification limits.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) quality control checks parameters such as acid value, saponification value, hydroxyl value, moisture content, oxyethylene content, residue on ignition, and lead content.
Material Safety Data Sheet (MSDS) of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Handling of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) should be handled in accordance with good industrial hygiene and safety practices.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) handling requires avoiding contact with eyes, skin, and clothing, and avoiding breathing mist or aerosols.
SDS of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Stability and Reactivity of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Chemical stability:
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) is stable under recommended storage and handling conditions.
Reactivity:
No dangerous reaction is expected under normal conditions of use.
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) may react with strong oxidizing agents, strong acids, or strong bases.
Conditions to avoid:
Excessive heat.
Open flames.
Direct sunlight.
Freezing.
Contamination.
Incompatible materials:
Strong oxidizing agents.
Strong acids.
Strong bases.
Reactive chemicals.
Hazardous decomposition products:
Carbon monoxide (CO).
Carbon dioxide (CO2).
Irritating organic fumes.
Handling and Storage of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Handling:
Handle in accordance with good industrial hygiene and safety practices.
Avoid contact with eyes, skin, and clothing.
Avoid breathing mist or aerosols.
Storage:
Store in a cool, dry, and well-ventilated area.
Keep container tightly closed when not in use.
Protect from heat, direct sunlight, freezing, and contamination.
Keep in original sealed containers or suitable HDPE/plastic packaging.
First Aid Measures of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Inhalation:
Move person to fresh air.
If breathing difficulty or irritation occurs, seek medical attention.
Skin contact:
Wash affected area with plenty of water and soap.
Remove contaminated clothing.
Seek medical advice if irritation persists.
Eye contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth with water.
Do not induce vomiting unless instructed by medical personnel.
Seek medical advice if symptoms occur.
Firefighting Measures of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Suitable extinguishing media:
Water spray.
Foam.
Dry chemical powder.
Carbon dioxide (CO2).
Specific hazards:
Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434) may burn under fire conditions.
Combustion may produce carbon monoxide, carbon dioxide, and irritating organic fumes.
Protective equipment for firefighters:
Wear self-contained breathing apparatus (SCBA).
Wear full protective clothing during firefighting operations.
Accidental Release Measures of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Personal precautions:
Avoid contact with skin and eyes.
Use suitable protective equipment.
Surfaces may become slippery after spillage.
Environmental precautions:
Prevent large spills from entering drains, waterways, or soil.
Cleanup methods:
Absorb with inert material such as sand, earth, or absorbent granules.
Collect into suitable labeled containers for disposal.
Wash spill area with water after collection.
Exposure Controls / Personal Protective Equipment of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Engineering controls:
Use adequate ventilation, especially where mist or aerosols may be generated.
Eye protection:
Wear safety goggles or face shield.
Skin protection:
Wear chemical-resistant gloves and protective clothing.
Respiratory protection:
Not normally required under good ventilation.
Use suitable respiratory protection if mist or aerosols are generated.
Hygiene measures:
Wash hands after handling.
Do not eat, drink, or smoke while using the product.
Identifiers of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
E Number: E434
INS Number: 434
CAS No.: 9005-66-7
EC No.: 500-020-4
FDA UNII: STI11B5A2X
COSING REF No.: 79320
HLB value: Approximately 15.6
Chemical class: Nonionic surfactant / Polysorbate / Sorbitan ester
Function: Emulsifier, solubilizer, wetting agent, stabilizer, dispersant, antistatic agent
Properties of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Physical state: Liquid or paste
Appearance: Pale yellow to orange viscous oily liquid or paste
Odor: Mild characteristic odor
Specific gravity: Approximately 1.083 at 25 degrees C
Refractive index: Approximately 1.470 at 20 degrees C
Flash point: Above 110 degrees C
Solubility: Soluble or dispersible in water; soluble in ethanol, ethyl acetate, and toluene
Ionic character: Nonionic
Emulsion type: Oil-in-water (O/W)
HLB value: Approximately 15.6
Specifications of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Chemical name: Polyoxyethylene(20) Sorbitan Monopalmitate (Polysorbate 40)
Acid value (mg KOH/g): ≤2.0
Saponification value (mg KOH/g): 41-52
Hydroxyl value (mg KOH/g): 90-107
Moisture (w/%): ≤3.0
Residue on ignition (w/%): ≤0.25
Lead (Pb) (mg/kg): ≤2
Oxyethylene (w/%): 66.0-70.5
Storage conditions: Store in a cool, dry, well-ventilated area in original sealed containers
Names of Polyoxyethylene Sorbitan Monopalmitate (Polysorbate 40) (E434):
Polyoxyethylene Sorbitan Monopalmitate
Polysorbate 40
E434
INS 434
Polyoxyethylene(20) Sorbitan Monopalmitate
PEG-20 Sorbitan Monopalmitate
Sorbitan Monopalmitate Ethoxylated
Ethoxylated Sorbitan Monopalmitate
Sorbimacrogol Palmitate 300
Tween 40
