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A polymer composed of Polyoxyethylene sorbitan monopalmitate; Polysorbate 40, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a palmitoyl group.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is a potent surfactant used in cosmetics to aid the mixing of oil- and water-based ingredients.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 also prevents the separation of different ingredients in a formulation and thus maintains product efficacy.
CAS: 9005-66-7
MF: C12H18O11
MW: 338.26472
Synonyms
POLYSORBATE 40;POLYOXYETHYLENE SORBITAN MONOPALMITATE;POLYOXYETHYLENE GLYCOL SORBITAN MONOPALMITATE;POLYOXYETHYLENE (20) SORBITAN MONOPALMITATE;POLYSORBATE40,NF;Sorbitanmonopalmitat, ethoxiliert, EO 20 mol;TWEEN NO 40;TWEEN(R) 40
As a dispersing agent, Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 widely used ingredient helps distribute pigments and active ingredients evenly.
While having little direct impact on skin and hair health, Polysorbate 40 works miraculously in the background to hold everything together in a product.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 may sometimes function as a mild conditioning and anti-static agent as well.
Also called polyoxyethylene sorbitan monopalmitate, Polysorbate 40 appears as a yellow to orange viscous liquid in its raw form.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 has the molecular formula C62H122O26.
Polyoxyethylenesorbitan monopalmitate, or Polyoxyethylene sorbitan monopalmitate; Polysorbate 40, is a non-ionic detergent.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 also known as Tween 40, the full name polyoxyethylene (20) sorbitan monopalmitate, 40 means monopalmitate.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is an emulsifier and stabiliser in food with the European food additive number E434.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is a mixture of the partial esters of sorbitol and its mono-and dianhydrides with edible palmitic acid and condensed with approximately 20 moles of ethylene oxide per mole of sorbitol and its anhydrides.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is a surfactant which is used as an emulsifier, solubilizer and stabilizer in many pharmaceuticals, foods, and cosmetic products.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 can be derived from sorbitol which is a plant-derived sugar alcohol, or bovine tallow which is a fat derived from cattle.
In the past few decades, there has been a move towards plant-derived fatty acids due to safety and sustainability concerns, however, Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is still important to confirm with manufacturers regarding product formulations.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is an amber oily liquid.
Relative density: 1.05-1.10. HLB value is 15.6.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is soluble in water, diluted acid, diluted alkalis, and most organic solvents, insoluble in vegetable oil.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is also called Polysorbate-40.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 Chemical Properties
Melting point: 0.1 °C
Boiling point: 797.89°C (rough estimate)
density: 1.083 g/mL at 25 °C(lit.)
refractive index: n20/D 1.47(lit.)
Fp: >230 °F
storage temp.: Store below +30°C.
solubility: Miscible with water, with anhydrous ethanol, with ethyl acetate and with methanol, practically insoluble in fatty oils and in liquid paraffin.
form: viscous liquid
Specific Gravity: 1.090 (25/4℃)
color: Light yellow to Yellow to Orange
Water Solubility: 100 g/L
Hydrophilic-Lipophilic Balance (HLB): 15.6
Cosmetics Ingredients Functions SURFACTANT - CLEANSING
SURFACTANT - EMULSIFYING
InChI: InChI=1/C12H18O11/c13-1-3(15)9-8(19)10(11(20)22-9)23-12-7(18)6(17)5(16)4(2-14)21-12/h3-7,9,12-19H,1-2H2/t3-,4+,5+,6-,7+,9+,12/s3
InChIKey: MLSJBGYKDYSOAE-YRYTZYTINA-NN&1:6,9,11,13,18,19,r|
EPA Substance Registry System: Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 (9005-66-7)
Uses
Pharmaceutic aid (surfactant)Note—Graphic formula same as for Polysorbate 20, except that R is (C15H31)COO.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is an emulsifier and stabilizer of essential oils in water.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is also a detergent and employed in a variety of cleansing and moisturizing preparations.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is a non-ionic surfactant used as an inner antistatic agent.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 is an ingredient that helps keep products like food, medicine, and cosmetics smooth and well-mixed.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 works by helping things that usually don’t blend—like oil and water—stay together in a uniform mixture.
Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 also helps retain moisture to prevent staleness in foods and other products and enhances drug delivery by improving solubility and absorption, making it particularly important for liquid medications, injections, and vaccines.
Additionally, Polyoxyethylene sorbitan monopalmitate; Polysorbate 40 contributes to product stability, appearance, texture, and overall effectiveness.
