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POLYOXYETHYLENE SORBITAN TRISTEARATE; POLYSORBATE 65

Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a polyoxyethylene sorbitan monooleate (polysorbate) surfactant that is used as a film-forming polymer and dispersing agent in solid preparations. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 has been shown to inhibit the proliferation of prostate cancer cells, which may be due to its ability to bind to anti-prostate specific antigen (anti-pcsk9) antibody causing the antibody to aggregate and form a particle. 
This process inhibits the interaction between the antibody and its target, preventing Polyoxyethylene sorbitan tristearate; Polysorbate 65 from binding with PCSK9 protein. 

CAS:    9005-71-4
EINECS:    500-019-9

Synonyms
Polysprbate65;Tween 65 Polysorbate 65;POE20;POLYETHYLENEGLYCOLSORBITANTRISTEARATE;POLYOXYETHYLENE-1,4-SORBITAN-TRISTEARATE;Sorbitantristearat, EO 20 mol;POLYOXYETHYLENE(20) SORBITAN TRISTEARATE(TWEEN (R) 65);Ahco 7166T

The addition of propranolol hydrochloride has been shown to increase the effectiveness of Polyoxyethylene sorbitan tristearate; Polysorbate 65.
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a 100% bio-based ethoxylated sorbitan ester derived from a natural fatty acid (palmitic acid). 
This ethoxylate excels in creating oil-in-water (O/W) emulsions and is suitable for various applications such as hard surface cleaning, industrial and institutional cleaning, and waxes and polishes.
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a high-quality, food-grade emulsifier known for its exceptional ability to stabilize and blend ingredients in various formulations. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is derived from sorbitol and oleic acid, making it an ideal choice for applications requiring a reliable emulsifying agent. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is widely used in the food industry to improve texture and consistency in products such as baked goods, ice creams, and salad dressings. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65's kosher certification ensures it meets strict dietary standards, making it suitable for a wide range of consumers. 

Additionally, this emulsifier is utilized in the cosmetic and pharmaceutical industries to enhance the stability and performance of creams, lotions, and other topical formulations. 
With its excellent solubilizing properties, Polyoxyethylene sorbitan tristearate; Polysorbate 65is an essential ingredient for manufacturers seeking to achieve uniformity and quality in their products.
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is the abbreviation of “polyoxyethylene (20) sorbitan”. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a surfactant type polysorbate whose stability and relative non-toxicity allow it to be used as a detergent and emulsifier in the food, industrial, cosmetic, and pharmaceutical industries. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a substance that helps mix ingredients together smoothly in food, medicine, and beauty products. 
Sometimes Polyoxyethylene sorbitan tristearate; Polysorbate 65's called Tween 65. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 helps things look and feel stable and nice. 

Polyoxyethylene sorbitan tristearate; Polysorbate 65 Chemical Properties
Fp: 149 °C
storage temp.: Store at RT.
form: solid
color: Colorless to light yellow
Hydrophilic-Lipophilic Balance (HLB): 10.5
Cosmetics Ingredients Functions: SURFACTANT - EMULSIFYING SURFACTANT - CLEANSING
EPA Substance Registry System: Polyoxyethylene sorbitan tristearate; Polysorbate 65 (9005-71-4)

Tan, waxy solid; faint odor, bitter taste. 
Sol in mineral oil, vegetable oil, mineral spirits, acetone, ether, dioxane, alc, methanol; dispersible in water, carbon tetrachloride.

Uses    
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is an emulsifier manufactured by reacting stearic acid with sorbitol to yield a product which is then reacted with ethylene oxide. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a nonionic surfaceactive agent which is dispersible in fat, oil, and water. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is also termed polysorbate 65. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is used in frozen desserts, cakes, and coffee whiteners. 
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is frequently used with sorbitan monostearates or monoand diglycerides. 
Typical usage range is 0.10–0.40%.
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is a mid-range HLB, nonionic surfactant suggested for use in textile chemicals (lubricant, emulsifier), household products (o/w emulsifier) and cosmetic formulations (o/w emulsifier).
Polyoxyethylene sorbitan tristearate; Polysorbate 65 is used as an emulsifier. 
Suggested applications: ice cream, cakes and cake icings.

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